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Pergamon or Pergamum ( / ˈ p ɜːr ɡ ə m ə n / or / ˈ p ɜːr ɡ ə m ɒ n / ; Ancient Greek : Πέργαμον ), also referred to by its modern Greek form Pergamos ( Πέργαμος ), was a rich and powerful ancient Greek city in Aeolis . It is located 26 kilometres (16 mi) from the modern coastline of the Aegean Sea on a promontory on the north side of the river Caicus (modern-day Bakırçay ) and northwest of the modern city of Bergama , Turkey .

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200-560: Aelius Galenus or Claudius Galenus ( Greek : Κλαύδιος Γαληνός ; September 129 – c.  216 AD), often anglicized as Galen ( / ˈ ɡ eɪ l ən / ) or Galen of Pergamon , was a Roman and Greek physician , surgeon , and philosopher . Considered to be one of the most accomplished of all medical researchers of antiquity , Galen influenced the development of various scientific disciplines, including anatomy , physiology , pathology , pharmacology , and neurology , as well as philosophy and logic . The son of Aelius Nicon ,

400-498: A cella divided into two rooms. The foundations, measuring around 12.70 x 21.80 metres, are still visible today. The columns were around 5.25 metres high, 0.75 metres in diameter, and the distance between the columns was 1.62 metres, so the colonnade was very light for a temple of this period. This is matched by the shape of the triglyphs , which usually consist of a sequence of two triglyphs and two metopes , but are instead composed of three of triglyphs and three metopes. The columns of

600-570: A basis for coinages: anthropology , photography , telephony , isomer , biomechanics , cinematography , etc. Together with Latin words , they form the foundation of international scientific and technical vocabulary ; for example, all words ending in -logy ('discourse'). There are many English words of Greek origin . Greek is an independent branch of the Indo-European language family. The ancient language most closely related to it may be ancient Macedonian , which, by most accounts,

800-661: A detailed depiction in high relief of the Gigantomachy , the battle between the Olympian gods and the Giants. The frieze is 2.30 metres high and has a total length of 113 metres, making it the second longest frieze surviving from antiquity, after the Parthenon Frieze in Athens. A 20-metre-wide (66 ft) staircase cut into the base on the western side leads up to the upper structure, which

1000-442: A dream in which the god Asclepius appeared and commanded Nicon to send his son to study medicine. Following his earlier liberal education, Galen at age 16 began his studies at the prestigious local healing temple or asclepeion as a θεραπευτής ( therapeutes , or attendant) for four years. There he came under the influence of men like Aeschrion of Pergamon , Stratonicus and Satyrus. Asclepiea functioned as spas or sanitoria to which

1200-552: A fairly stable set of consonantal contrasts . The main phonological changes occurred during the Hellenistic and Roman period (see Koine Greek phonology for details): In all its stages, the morphology of Greek shows an extensive set of productive derivational affixes , a limited but productive system of compounding and a rich inflectional system. Although its morphological categories have been fairly stable over time, morphological changes are present throughout, particularly in

1400-556: A faster, more convenient cursive writing style with the use of ink and quill . The Greek alphabet consists of 24 letters, each with an uppercase ( majuscule ) and lowercase ( minuscule ) form. The letter sigma has an additional lowercase form (ς) used in the final position of a word: In addition to the letters, the Greek alphabet features a number of diacritical signs : three different accent marks ( acute , grave , and circumflex ), originally denoting different shapes of pitch accent on

1600-399: A few traces of the Hellenistic structure survive. The majority of the surviving structure derives from a reconstruction of the temple which probably took place under Caracalla , or perhaps under Hadrian . Pergamon's oldest temple is a sanctuary of Athena from the 4th century BC. It was a north-facing Doric peripteros temple with six columns on the short side and ten on the long side and

1800-531: A foreign language. It is also often stated that the historical changes have been relatively slight compared with some other languages. According to one estimation, " Homeric Greek is probably closer to Demotic than 12-century Middle English is to modern spoken English ". Greek is spoken today by at least 13 million people, principally in Greece and Cyprus along with a sizable Greek-speaking minority in Albania near

2000-467: A free city. Henceforth the city was required to pay tribute and accommodate and supply Roman troops, and the property of many of the inhabitants was confiscated. Imported Pergamene goods were among the luxuries enjoyed by Lucullus . The members of the Pergamene aristocracy, especially Diodorus Pasparus in the 70s BC, used their own possessions to maintain good relationships with Rome, by acting as donors for

2200-521: A high retaining wall and was framed on the long side by a stoa . Coming from the Upper market, one could enter this from a tower-building at the south end. This terrace had no space for the circular orchestra , which was normal in a Greek theatre, so only a wooden stage building was built which could be taken down when there was no performance taking place. Thus, the view along the terrace to the Temple of Dionysos at

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2400-541: A library might indicate, however, that the building was located in that area. Other notable structures still in existence on the upper part of the Acropolis include: The site is today easily accessible by the Bergama Acropolis Gondola from the base station in northeastern Bergama. A large gymnasium area was built in the 2nd century BC on the south side of the Acropolis. It consisted of three terraces, with

2600-402: A male, preferably of an older, wiser, age, as well as free from the control of the passions. These passions, according to Galen, caused the psychological problems that people experienced. Galen may have produced more work than any author in antiquity, rivaling the quantity of work issued from Augustine of Hippo . So profuse was Galen's output that the surviving texts represent nearly half of all

2800-727: A materialist reading of Galen's philosophy of mind. According to this materialist reading, Galen identifies the soul with the mixtures of the body. Another one of Galen's major works, On the Diagnosis and Cure of the Soul's Passion , discussed how to approach and treat psychological problems. This was Galen's early attempt at what would later be called psychotherapy . His book contained directions on how to provide counsel to those with psychological issues to prompt them to reveal their deepest passions and secrets, and eventually cure them of their mental deficiency. The leading individual, or therapist, had to be

3000-723: A medical text both in the Latin Middle Ages and Medieval Islam . The 11th-century Suda lexicon states that Galen died at the age of 70, which would place his death in about the year 199. However, there is a reference in Galen's treatise "On Theriac to Piso" (which may, however, be spurious) to events of 204. There are also statements in Arabic sources that he died in Sicily at age 87, after 17 years studying medicine and 70 practicing it, which would mean he died about 216. According to these sources,

3200-421: A more complete understanding of the circulatory system, nervous system , respiratory system , and other structures, his work contained scientific errors. Galen believed the circulatory system to consist of two separate one-way systems of distribution, rather than a single unified system of circulation. He believed venous blood to be generated in the liver, from where it was distributed and consumed by all organs of

3400-552: A number of works attributed to Galen. As a consequence, research on Galen's work is fraught with hazard. Various attempts have been made to classify Galen's vast output. For instance Coxe (1846) lists a Prolegomena, or introductory books, followed by 7 classes of treatise embracing Physiology (28 vols.), Hygiene (12), Aetiology (19), Semeiotics (14), Pharmacy (10), Blood letting (4), and Therapeutics (17), in addition to 4 of aphorisms, and spurious works. The most complete compendium of Galen's writings, surpassing even modern projects like

3600-515: A pestilence occurred which at its height killed 2,000 people a day in Rome. This was most likely the same plague (the so-called "Antonine Plague" and most likely smallpox) that struck Rome during Marcus Aurelius' reign. Galen was also physician to Septimius Severus during his reign in Rome. He complimented Severus and Caracalla on keeping a supply of drugs for their friends and mentioned three cases in which they had been of use in 198. The Antonine Plague

3800-484: A physician and a philosopher, as he wrote in his treatise titled That the Best Physician Is Also a Philosopher . Galen was very interested in the debate between the rationalist and empiricist medical sects, and his use of direct observation, dissection, and vivisection represents a complex middle ground between the extremes of those two viewpoints. Many of his works have been preserved and/or translated from

4000-472: A pig, and while it was squealing he would tie off the recurrent laryngeal nerve, or vocal cords, showing they controlled the making of sound. He used the same method to tie off the ureters to prove his theories of kidney and bladder function. Galen believed the human body had three interconnected systems that allowed it to work. The first system that he theorized consisted of the brain and the nerves, responsible for thought and sensation. The second theorized system

4200-460: A practicing physician. His public demonstrations and impatience with alternative views on medicine brought him into conflict with other doctors practicing in the city. When the Peripatetic philosopher Eudemus became ill with quartan fever , Galen felt obliged to treat him "since he was my teacher and I happened to live nearby". He wrote: "I return to the case of Eudemus. He was thoroughly attacked by

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4400-444: A second neocorate, from Trajan in AD 113/4. Hadrian raised the city to the rank of metropolis in 123 and thereby elevated it above its local rivals, Ephesus and Smyrna . An ambitious building programme was carried out: massive temples, a stadium, a theatre , a huge forum and an amphitheatre were constructed. In addition, at the city limits the shrine to Asclepius (the god of healing)

4600-399: A staircase of eleven steps around 7.5 metres wide, descending from the front of the temple. The temple was about 7 metres wide by 12 metres long, and sat on a three-stepped foundation. It was a Doric tetrastyle prostyle temple, with three triglyphs and metopes for each span in the entablature. All the other buildings in the sanctuary were made out of trachyte , but the visible part of

4800-476: A wealthy Greek architect with scholarly interests, Galen received a comprehensive education that prepared him for a successful career as a physician and philosopher. Born in the ancient city of Pergamon (present-day Bergama , Turkey), Galen traveled extensively, exposing himself to a wide variety of medical theories and discoveries before settling in Rome , where he served prominent members of Roman society and eventually

5000-517: A young man had come to the city and had given, like me practical demonstrations of the resources of our art; this young man was put to death by poison, together with two servants who accompanied him." When Galen's animosity with the Roman medical practitioners became serious, he feared he might be exiled or poisoned, so he left the city. Rome was engaged in foreign wars in 161; Marcus Aurelius and his then co-Emperor and adoptive brother Lucius Verus were in

5200-408: Is a mixture of nutritious blood from the liver and the vital spirit (the soul) which was attained from the lungs. The vital spirit within this medium was necessary for the body to function and eventually completely absorbed. This process was then repeated indefinitely, according to Galen, so that the body could be replenished with the soul, or the vital spirit. Several schools of thought existed within

5400-766: Is also found in Bulgaria near the Greek-Bulgarian border. Greek is also spoken worldwide by the sizable Greek diaspora which has notable communities in the United States , Australia , Canada , South Africa , Chile , Brazil , Argentina , Russia , Ukraine , the United Kingdom , and throughout the European Union , especially in Germany . Historically, significant Greek-speaking communities and regions were found throughout

5600-742: Is an Indo-European language, constituting an independent Hellenic branch within the Indo-European language family. It is native to Greece , Cyprus , Italy (in Calabria and Salento ), southern Albania , and other regions of the Balkans , Caucasus , the Black Sea coast, Asia Minor , and the Eastern Mediterranean . It has the longest documented history of any Indo-European language, spanning at least 3,400 years of written records. Its writing system

5800-474: Is an Indo-European language, but also includes a number of borrowings from the languages of the populations that inhabited Greece before the arrival of Proto-Greeks, some documented in Mycenaean texts ; they include a large number of Greek toponyms . The form and meaning of many words have changed. Loanwords (words of foreign origin) have entered the language, mainly from Latin, Venetian , and Turkish . During

6000-514: Is centered on a 335-metre-high (1,100 ft) mesa of andesite , which formed its acropolis . This mesa falls away sharply on the north, west, and east sides, but three natural terraces on the south side provide a route up to the top. To the west of the acropolis, the Selinus River (modern Bergamaçay) flows through the city, while the Cetius river (modern Kestelçay) passes by to the east. Pergamon

6200-555: Is mostly composed of volcanic rock, particularly andesite, and the Pergamon massif is also an intrusive stock of andesite. The massif is about one kilometre wide and around 5.5 km long from north to south. It consists of a broad, elongated base and a relatively small peak - the upper city. The side facing the Cetius river is a sharp cliff, while the side facing the Selinus is a little rough. On

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6400-594: Is not mentioned in Greek myth or epic of the archaic or classical periods. However, in the Epic Cycle the Telephus myth is already connected with the area of Mysia. Searching for his mother, Telephus visits Mysia on the advice of an oracle. There he becomes Teuthras ' son-in-law or foster-son and inherits his kingdom of Teuthrania , encompassing the area between Pergamon and the mouth of the Caicus. Telephus refuses to participate in

6600-467: Is only 26 km from the sea, but the Caicus plain is not open to the sea, since the way is blocked by the Karadağ massif. As a result, the area has a strongly inland character. In Hellenistic times, the town of Elaia at the mouth of the Caicus served as the port of Pergamon. The climate is Mediterranean with a dry period from May to August, as is common along the west coast of Asia Minor. The Caicus valley

6800-510: Is protected and promoted officially as a regional and minority language in Armenia, Hungary , Romania, and Ukraine. It is recognized as a minority language and protected in Turkey by the 1923 Treaty of Lausanne . The phonology , morphology , syntax , and vocabulary of the language show both conservative and innovative tendencies across the entire attestation of the language from the ancient to

7000-710: Is sometimes called aljamiado , as when Romance languages are written in the Arabic alphabet. Article 1 of the Universal Declaration of Human Rights in Greek: Transcription of the example text into Latin alphabet : Article 1 of the Universal Declaration of Human Rights in English: Proto-Greek Mycenaean Ancient Koine Medieval Modern Pergamon During

7200-518: Is spoken by at least 13.5 million people today in Greece, Cyprus, Italy, Albania, Turkey , and the many other countries of the Greek diaspora . Greek roots have been widely used for centuries and continue to be widely used to coin new words in other languages; Greek and Latin are the predominant sources of international scientific vocabulary . Greek has been spoken in the Balkan peninsula since around

7400-758: Is still used internationally for the writing of Ancient Greek . In Greek, the question mark is written as the English semicolon, while the functions of the colon and semicolon are performed by a raised point (•), known as the ano teleia ( άνω τελεία ). In Greek the comma also functions as a silent letter in a handful of Greek words, principally distinguishing ό,τι ( ó,ti , 'whatever') from ότι ( óti , 'that'). Ancient Greek texts often used scriptio continua ('continuous writing'), which means that ancient authors and scribes would write word after word with no spaces or punctuation between words to differentiate or mark boundaries. Boustrophedon , or bi-directional text,

7600-460: Is surrounded by a colonnade, and consists of a colonnaded courtyard, separated from the staircase by a colonnade. The interior walls of this colonnade had a further frieze, depicting the life of Telephus , the son of Heracles and mythical founder of Pergamon. This frieze is around 1.60 metres high and thus is clearly smaller than the outer frieze. In the New Testament Book of Revelation ,

7800-630: Is the Greek alphabet , which has been used for approximately 2,800 years; previously, Greek was recorded in writing systems such as Linear B and the Cypriot syllabary . The alphabet arose from the Phoenician script and was in turn the basis of the Latin , Cyrillic , Coptic , Gothic , and many other writing systems. The Greek language holds a very important place in the history of the Western world. Beginning with

8000-399: Is the steepest of all ancient theatres. The seating area ( koilon ) is divided horizontally by two walkways, called diazomata , and vertically by 0.75-metre-wide (2.5 ft) stairways into seven sections in the lowest part of the theatre and six in the middle and upper sections. Below the theatre is a 247-metre-long (810 ft) and up to 17.4-metre-wide (57 ft) terrace, which rested on

8200-501: The Corpus Medicorum Graecorum/Latinorum  [ de ] , is the one compiled and translated by Karl Gottlob Kühn of Leipzig between 1821 and 1833. This collection consists of 122 of Galen's treatises, translated from the original Greek into Latin (the text is presented in both languages). Over 20,000 pages in length, it is divided into 22 volumes, with 676 index pages. Many of Galen's works are included in

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8400-702: The Thesaurus Linguae Graecae , a digital library of Greek literature started in 1972. Another useful modern source is the French Bibliothèque interuniversitaire de médecine Archived 2014-04-21 at the Wayback Machine (BIUM). In his time, Galen's reputation as both physician and philosopher was legendary, the emperor Marcus Aurelius describing him as "Primum sane medicorum esse, philosophorum autem solum" (first among doctors and unique among philosophers Praen 14: 660 ). Other contemporary authors in

8600-545: The Bronze Age cannot be demonstrated, although Bronze Age stone tools are found in the surrounding area. The earliest mention of Pergamon in literary sources comes from Xenophon 's Anabasis , since the march of the Ten Thousand under Xenophon's command ended at Pergamon in 400/399 BC. Xenophon, who calls the city Pergamos, handed over the rest of his Greek troops (some 5,000 men according to Diodorus ) to Thibron , who

8800-538: The Corinthian order . A roofed stadium , known as the Basement Stadium is located between the middle terrace and the upper terrace. The upper terrace measured 150 x 70 metres square, making it the largest of the three terraces. It consisted of a courtyard surrounded by stoas and other structures, measuring roughly 36 x 74 metres. This complex is identified as a palaestra and had a theatre-shaped lecture hall beyond

9000-486: The Eastern Mediterranean , in what are today Southern Italy , Turkey , Cyprus , Syria , Lebanon , Israel , Palestine , Egypt , and Libya ; in the area of the Black Sea , in what are today Turkey, Bulgaria , Romania , Ukraine , Russia , Georgia , Armenia , and Azerbaijan ; and, to a lesser extent, in the Western Mediterranean in and around colonies such as Massalia , Monoikos , and Mainake . It

9200-602: The First World War and were only resumed in 1927 under the leadership of Theodor Wiegand , who remained in this post until 1939. He concentrated on further excavation of the upper city, the Asklepieion, and the Red Basilica . The Second World War also caused a break in work at Pergamon, which lasted until 1957. From 1957 to 1968, Erich Boehringer worked on the Asklepieion in particular, but also carried out important work on

9400-652: The Fourth Crusade , Pergamon became part of the Empire of Nicaea . When Emperor Theodore II Laskaris ( r.  1254–1285 ) visited Pergamon in 1250, he was shown the house of Galen, but he saw that the theatre had been destroyed and, except for the walls which he paid some attention to, only the vaults over the Selinus seemed noteworthy to him. The monuments of the Attalids and the Romans were only plundered ruins by this time. With

9600-638: The Hellenistic period , it became the capital of the Kingdom of Pergamon in 281–133 BC under the Attalid dynasty, who transformed it into one of the major cultural centres of the Greek world. Many remains of its monuments can still be seen and especially the masterpiece of the Pergamon Altar . Pergamon was the northernmost of the seven churches of Asia cited in the New Testament Book of Revelation . The city

9800-510: The Indo-Iranian languages (see Graeco-Aryan ), but little definitive evidence has been found. In addition, Albanian has also been considered somewhat related to Greek and Armenian, and it has been proposed that they all form a higher-order subgroup along with other extinct languages of the ancient Balkans; this higher-order subgroup is usually termed Palaeo-Balkan , and Greek has a central position in it. Linear B , attested as early as

10000-632: The Muslim conquests ; this community produced the emperor Philippicus ( r.  711–713 ). In 716, Pergamon was sacked again by the armies of Maslama ibn Abd al-Malik . It was again rebuilt and refortified after the Arabs abandoned their Siege of Constantinople in 717–718. Pergamon suffered from the Seljuk invasion of western Anatolia after the Battle of Manzikert in 1071. Attacks in 1109 and 1113 largely destroyed

10200-627: The Ptolemies derived themselves directly from Heracles, the Antigonids inserted Heracles into their family tree in the reign of Philip V at the end of the 3rd century BC at the latest, and the Seleucids claimed descent from Apollo . All of these claims derive their significance from Alexander the Great , who claimed descent from Heracles, through his father Philip II . In their constructive adaptation of

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10400-574: The Pyrrhonists . Galen was concerned to combine philosophical thought with medical practice, as in his brief work That the Best Physician is also a Philosopher he took aspects from each group and combined them with his original thought. He regarded medicine as an interdisciplinary field that was best practiced by utilizing theory, observation, and experimentation in conjunction. Galen combined his observations of his dissections with Plato's theory about

10600-467: The Renaissance . Some of Galen's treatises have appeared under many different titles over the years. Sources are often in obscure and difficult-to-access journals or repositories. Although written in Greek, by convention the works are referred to by Latin titles, and often by merely abbreviations of those. No single authoritative collection of his work exists, and controversy remains as to the authenticity of

10800-463: The Third Macedonian War , but the Romans heard rumours of his conducting secret negotiations with their opponent Perseus of Macedon . On this basis, Rome denied any reward to Pergamon and attempted to replace Eumenes with the future Attalus II, who refused to cooperate. These incidents cost Pergamon its privileged status with the Romans, who granted it no further territory. Nevertheless, under

11000-508: The Trojan War , but his son Eurypylus fights on the side of the Trojans . This material was dealt with in a number of tragedies, such as Aeschylus ' Mysi , Sophocles ' Aleadae , and Euripides ' Telephus and Auge , but Pergamon does not seem to have played any role in any of them. The adaptation of the myth is not entirely smooth. Thus, on the one hand, Eurypylus who must have been part of

11200-538: The dissection of Barbary apes . However, when he discovered that their facial expressions were too much like those of humans, he switched to other animals, such as pigs . While dissections and vivisections on humans were practised in Alexandria at this time, Galen did not have Imperial permission to perform his own, and had to use animals instead. Galen would encourage his students to go look at dead gladiators or bodies that washed up in order to get better acquainted with

11400-583: The extant literature from ancient Greece. It has been reported that Galen employed twenty scribes to write down his words. Galen may have written as many as 500 treatises, amounting to some 10 million words. Although his surviving works amount to some 3 million words, this is thought to represent less than a third of his complete writings. In 191, or more likely in 192, a fire in the Temple of Peace destroyed many of his works, in particular treatises on philosophy. Because Galen's works were not translated into Latin in

11600-492: The nominal and verbal systems. The major change in the nominal morphology since the classical stage was the disuse of the dative case (its functions being largely taken over by the genitive ). The verbal system has lost the infinitive , the synthetically -formed future, and perfect tenses and the optative mood . Many have been replaced by periphrastic ( analytical ) forms. Pronouns show distinctions in person (1st, 2nd, and 3rd), number (singular, dual , and plural in

11800-462: The pulmonary circulation contradicted the Galenic theory on the heart. The influence of Galen's writings, including humorism, remains strong in modern Unani medicine , now closely identified with Islamic culture, and widely practiced from India (where it is officially recognized) to Morocco. Maimonides was influenced by Galen, whom he cited most often in his medical works, and whom he considered to be

12000-568: The "medical refrigerators of antiquity". In late antiquity, medical writing veered increasingly in the direction of the theoretical at the expense of the practical, with many authors merely debating Galenism. Magnus of Nisibis was a pure theorist, as were John of Alexandria and Agnellus of Ravenna with their lectures on Galen's De Sectis . So strong was Galenism that other authors such as Hippocrates began to be seen through Galen's eyes, while his opponents became marginalised and other medical sects such as Asclepiadism slowly disappeared. Greek medicine

12200-423: The 13th century. Beginning with Ciriaco de' Pizzicolli in the 15th century, ever more travellers visited the place and published their accounts of it. The key description is that of Thomas Smith, who visited the Levant in 1668 and transmitted a detailed description of Pergamon, to which the great 17th century travellers Jacob Spon and George Wheler were able to add nothing significant in their own accounts. In

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12400-432: The 13th century. However, Galen's influence was so great that when dissections discovered anomalies compared with Galen's anatomy, the physicians often tried to fit these into the Galenic system. An example of this is Mondino de Liuzzi , who describes rudimentary blood circulation in his writings but still asserts that the left ventricle should contain air. Some cited these changes as proof that human anatomy had changed since

12600-437: The 3rd century BC, when the Attalids made him the chief god of their dynasty. In the 2nd century BC, Eumenes II (probably) built a temple for Dionysus at the northern end of the theatre terrace. The marble temple sits on a podium, 4.5 metres above the level of the theatre terrace and was an Ionic prostyle temple. The pronaos was four columns wide and two columns deep and was accessed by a staircase of twenty-five steps. Only

12800-415: The 3rd millennium BC, or possibly earlier. The earliest written evidence is a Linear B clay tablet found in Messenia that dates to between 1450 and 1350 BC, making Greek the world's oldest recorded living language . Among the Indo-European languages, its date of earliest written attestation is matched only by the now-extinct Anatolian languages . The Greek language is conventionally divided into

13000-426: The Arabic. In some cases scholars have even attempted to translate from the Latin or Arabic back into Greek where the original is lost. For some of the ancient sources, such as Herophilus , Galen's account of their work is all that survives. Even in his own time, forgeries and unscrupulous editions of his work were a problem, prompting him to write On His Own Books . Forgeries in Latin, Arabic or Greek continued until

13200-461: The Byzantine Empire. All of the extant Greek manuscripts of Galen were copied by Byzantine scholars. In the Abbasid period (after 750) Arab Muslims began to be interested in Greek scientific and medical texts for the first time, and had some of Galen's texts translated into Arabic, often by Syrian Christian scholars (see below). As a result, some texts of Galen exist only in Arabic translation, while others exist only in medieval Latin translations of

13400-434: The Caicus, mistook it for Troy and began to ravage the land. On the other hand, the story was linked to the foundation of the city with another myth – that of Pergamus , the eponymous hero of the city. He also belonged to the broader cycle of myths related to the Trojan War as the grandson of Achilles through his father Neoptolemus and of Eetion of Thebe through his mother Andromache (concubine to Neoptolemus after

13600-486: The Greek alphabet since approximately the 9th century BC. It was created by modifying the Phoenician alphabet , with the innovation of adopting certain letters to represent the vowels. The variant of the alphabet in use today is essentially the late Ionic variant, introduced for writing classical Attic in 403 BC. In classical Greek, as in classical Latin, only upper-case letters existed. The lower-case Greek letters were developed much later by medieval scribes to permit

13800-425: The Greek language are often emphasized. Although Greek has undergone morphological and phonological changes comparable to those seen in other languages, never since classical antiquity has its cultural, literary, and orthographic tradition been interrupted to the extent that one can speak of a new language emerging. Greek speakers today still tend to regard literary works of ancient Greek as part of their own rather than

14000-442: The Greek language was the Cypriot syllabary (also a descendant of Linear A via the intermediate Cypro-Minoan syllabary ), which is closely related to Linear B but uses somewhat different syllabic conventions to represent phoneme sequences. The Cypriot syllabary is attested in Cyprus from the 11th century BC until its gradual abandonment in the late Classical period, in favor of the standard Greek alphabet. Greek has been written in

14200-629: The Greek verb have likewise remained largely the same over the course of the language's history but with significant changes in the number of distinctions within each category and their morphological expression. Greek verbs have synthetic inflectional forms for: Many aspects of the syntax of Greek have remained constant: verbs agree with their subject only, the use of the surviving cases is largely intact (nominative for subjects and predicates, accusative for objects of most verbs and many prepositions, genitive for possessors), articles precede nouns, adpositions are largely prepositional, relative clauses follow

14400-654: The Greek world confirm this including Theodotus the Shoemaker , Athenaeus and Alexander of Aphrodisias . The 7th-century poet George of Pisida went so far as to refer to Christ as a second and neglected Galen. Galen continued to exert an important influence over the theory and practice of medicine until the mid-17th century in the Byzantine and Arabic worlds and Europe. A few centuries after Galen, Palladius Iatrosophista stated in his commentary on Hippocrates that Hippocrates sowed and Galen reaped. Galen summarized and synthesized

14600-456: The Greek, such as Burgundio of Pisa 's translation of De complexionibus . Galen's works on anatomy and medicine became the mainstay of the medieval physician's university curriculum, alongside Ibn Sina's The Canon of Medicine , which elaborated on Galen's works. Unlike pagan Rome, Christian Europe did not exercise a universal prohibition of the dissection and autopsy of the human body and such examinations were carried out regularly from at least

14800-661: The Greek-Albanian border. A significant percentage of Albania's population has knowledge of the Greek language due in part to the Albanian wave of immigration to Greece in the 1980s and '90s and the Greek community in the country. Prior to the Greco-Turkish War and the resulting population exchange in 1923 a very large population of Greek-speakers also existed in Turkey , though very few remain today. A small Greek-speaking community

15000-449: The Pergamon museum in Berlin, where the parts of the frieze taken to Germany have been installed in a partial reconstruction. For the altar's construction, the required flat area was skillfully created through terracing, in order to allow it to be oriented in relation to the neighbouring Temple of Athena. The base of the altar measured around 36 x 33 metres and was decorated on the outside with

15200-460: The Persian Empire. Only with Alexander the Great were Pergamon and the surrounding area removed from Persian control. There are few traces of the pre-Hellenistic city, since in the following period the terrain was profoundly changed and the construction of broad terraces involved the removal of almost all earlier structures. Parts of the temple of Athena , as well as the walls and foundations of

15400-529: The Rationalist sect and from the Empiricist sect. Galen was well known for his advancements in medicine and the circulatory system, but he was also concerned with philosophy. He developed his own tripartite soul model following the examples of Plato; some scholars refer to him as a Platonist. Galen developed a theory of personality based on his understanding of fluid circulation in humans, and he believed that there

15600-434: The Roman period, his image appears on civic coinage and he is said to have had a heroon in the city. Even so, he provided a further, deliberately crafted link to the world of Homeric epic. Mithridates VI was celebrated in the city as a new Pergamus. However, for the Attalids, it was apparently the genealogical connection to Heracles that was crucial, since all the other Hellenistic dynasties had long established such links:

15800-517: The Stoics' lack of scientific justification discredited their claims of the separateness of mind and body, which is why he spoke so strongly against them. There is an intense scholarly debate about soul–body relations in Galen's psychological writings. In his brief treatise Quod animi mores , Galen says both that the soul "follows" the mixtures of the body, and that the soul is a bodily mixture. Scholars have offered ways of reconciling these claims, arguing for

16000-414: The Temple, the former sharing it with the latter. The temple sits on a 2.9-metre-high (9.5 ft) podium on top of a vaulted terrace. The temple itself was a Corinthian peripteros temple, about 18 metres wide with six columns on the short sides and nine columns on the long sides, and two rows of columns in antis . To the north, the area was closed off by a high stoa, while on the west and east sides it

16200-404: The acute during the late 20th century, and it has only been retained in typography . After the writing reform of 1982, most diacritics are no longer used. Since then, Greek has been written mostly in the simplified monotonic orthography (or monotonic system), which employs only the acute accent and the diaeresis. The traditional system, now called the polytonic orthography (or polytonic system),

16400-522: The advice he found in Hippocrates' teaching and traveled and studied widely including such destinations as Smyrna (now İzmir ), Corinth , Crete , Cilicia (now Çukurova ), Cyprus , and finally the great medical school of Alexandria , exposing himself to the various schools of thought in medicine. In 157, aged 28, he returned to Pergamon as physician to the gladiators of the High Priest of Asia, one of

16600-558: The affections of the mind . He was born in September 129 AD. His father, Aelius Nicon , was a wealthy patrician , an architect and builder, with eclectic interests including philosophy, mathematics, logic, astronomy, agriculture and literature. Galen describes his father as a "highly amiable, just, good and benevolent man". At that time Pergamon (modern-day Bergama , Turkey) was a major cultural and intellectual centre, noted for its library , second only to that in Alexandria, as well as being

16800-609: The alimentary tract via a patient's diarrhea and stools. If the stool was very black, the patient died. He says that the amount of black stools varied. It depended on the severity of the intestinal lesions. He observes that in cases where the stool was not black, the black exanthema appeared. Galen describes the symptoms of fever, vomiting, fetid breath, catarrh , cough, and ulceration of the larynx and trachea. Galen continued to work and write in his final years, finishing treatises on drugs and remedies as well as his compendium of diagnostics and therapeutics, which would have much influence as

17000-616: The altar in the sanctuary of Demeter , go back to the fourth century. Lysimachus , King of Thrace , took possession in 301 BC, and the town was enlarged by his lieutenant Philetaerus . In 281 BC the kingdom of Thrace collapsed and Philetaerus became an independent ruler, founding the Attalid dynasty . His family ruled Pergamon from 281 until 133 BC: Philetaerus 281–263; Eumenes I 263–241; Attalus I 241–197; Eumenes II 197–159; Attalus II 159–138; and Attalus III 138–133. Philetaerus controlled only Pergamon and its immediate environs, but

17200-402: The ancient language; singular and plural alone in later stages), and gender (masculine, feminine, and neuter), and decline for case (from six cases in the earliest forms attested to four in the modern language). Nouns, articles, and adjectives show all the distinctions except for a person. Both attributive and predicative adjectives agree with the noun. The inflectional categories of

17400-701: The ancient period, and because of the collapse of the Roman Empire in the West, the study of Galen, along with the Greek medical tradition as a whole, went into decline in Western Europe during the Early Middle Ages , when very few Latin scholars could read Greek. However, in general, Galen and the ancient Greek medical tradition continued to be studied and followed in the Eastern Roman Empire , commonly known as

17600-515: The archaeologist Alexander Conze took over direction of the department of ancient sculpture at the Royal Museums of Berlin , he quickly initiated a programme for the excavation and protection of the monuments connected to the sculpture, which were widely suspected to include the Great Altar. As a result of these efforts, Carl Humann, who had been carrying out low-level excavations at Pergamon for

17800-532: The beginning of the 3rd century Caracalla granted the city a third neocorate, but a decline had already set in. The economic strength of Pergamon collapsed during the crisis of the Third Century , as the city was badly damaged in an earthquake in 262 and was sacked by the Goths shortly thereafter. In late antiquity , it experienced a limited economic recovery. In AD 663/4, Pergamon was captured by raiding Arabs for

18000-456: The blood back into the lungs to be exhaled. In order to receive air from the lungs in the left ventricle, the new blood needed to get there from the right ventricle. Thus, Galen asserted that there are small holes in the septum dividing the left and right sides of the heart; these holes allowed the blood to pass through easily to receive air and exchange the aforementioned waste products. Although his anatomical experiments on animal models led him to

18200-476: The body and that the soul, as a whole, contributed to the health of the body, strengthening the "natural functioning capacity of the organ or organs in question". The rational soul controlled higher level cognitive functioning in an organism, for example, making choices or perceiving the world and sending those signals to the brain. He also listed "imagination, memory, recollection, knowledge, thought, consideration, voluntary motion, and sensation" as being found within

18400-452: The body to its function indicated the role of an intelligent creator. His creationism was anticipated by the anatomical examples of Socrates and Empedocles . Although the main focus of his work was on medicine, anatomy, and physiology, Galen also wrote about logic and philosophy. His writings were influenced by earlier Greek and Roman thinkers, including Plato , Aristotle , the Stoics , and

18600-501: The body. He posited that arterial blood originated in the heart, from where it was distributed and consumed by all organs of the body. The blood was then regenerated in either the liver or the heart, completing the cycle. Galen also believed in the existence of a group of blood vessels he called the rete mirabile in the carotid sinus. Both of these theories of the circulation of blood were later (beginning with works of Ibn al-Nafis published c.  1242 ) shown to be incorrect. Galen

18800-453: The body. More important is that it includes details of more than 150 single and compound formulations of both herbal and animal origin. The book provides an insight into understanding the traditions and methods of treatment in the Greek and Roman eras. In addition, this book provides a direct source for the study of more than 150 single and compound drugs used during the Greco-Roman period. As

19000-433: The brain. He conducted many anatomical studies on animals, most famously an ox, to study the transition from vital to psychic pneuma . Although highly criticized for comparing animal anatomy to human anatomy, Galen was convinced that his knowledge was abundant enough in both anatomies to base one on the other. In his treatise On the usefulness of the parts of the body , Galen argued that the perfect suitability of each part of

19200-406: The brothers Eumenes II and Attalus II, Pergamon reached its apex and was rebuilt on a monumental scale. It had retained the same dimensions for a long interval after its founding by Philetaerus, covering c. 21 hectares (52 acres). After 188 BC a massive new city wall was constructed, 4 kilometres (2.5 mi) long and enclosing an area of approximately 90 hectares (220 acres). The Attalids' goal

19400-472: The circulatory system. The blood created in the liver would eventually flow unidirectionally into the right ventricle of the heart via the great vein. Galen also proposed a theory on how blood receives air from the lungs to be distributed throughout the body. He declared that the venous artery carried air from the lungs into the left ventricle of the heart to mix with created blood from the liver. This same venous artery allowed for an exchange of waste products from

19600-611: The city acquired much new territory under Eumenes I. In particular, after the Battle of Sardis in 261 BC against Antiochus I , Eumenes was able to appropriate the area down to the coast and some way inland. Despite this increase of his domain, Eumenes did not take a royal title. In 238 his successor Attalus I defeated the Galatians , to whom Pergamon had paid tribute under Eumenes I. Attalus thereafter declared himself leader of an entirely independent Pergamene kingdom. The Attalids became some of

19800-453: The city and its ruins was first produced by Charles Texier when he published the second volume of his Description de l'Asie mineure . In 1864–5, the German engineer Carl Humann visited Pergamon for the first time. For the construction of the road from Pergamon to Dikili for which he had undertaken planning work and topographical studies, he returned in 1869 and began to focus intensively on

20000-531: The city, which was only rebuilt, by Emperor Manuel I Komnenos ( r.  1143–1180 ), around 1170. It likely became the capital of the new theme of Neokastra , established by Manuel. Under Isaac II Angelos ( r.  1185–1195 ), the local see was promoted to a metropolitan bishopric , having previously been a suffragan diocese of the Metropolis of Ephesus . After the Sack of Constantinople in 1204 during

20200-510: The crystalline lens is located in the anterior aspect of the human eye. At first reluctantly but then with increasing vigor, Galen promoted Hippocratic teaching, including venesection and bloodletting , then unknown in Rome. This was sharply criticized by the Erasistrateans , who predicted dire outcomes, believing that it was not blood but pneuma that flowed in the veins. Galen, however, staunchly defended venesection in his three books on

20400-542: The curriculum at the universities of Naples and Montpellier . From that time, Galenism took on a new, unquestioned authority, Galen even being referred to as the "Medical Pope of the Middle Ages". Constantine the African was amongst those who translated both Hippocrates and Galen from Arabic. In addition to the more numerous translations of Arabic texts in this period, there were a few translations of Galenic works directly from

20600-503: The death of Hector of Troy ). With his mother, he was said to have fled to Mysia where he killed the ruler of Teuthrania and gave the city his own name. There he built a heroon for his mother after her death. In a less heroic version, Grynos the son of Eurypylus named a city after him in gratitude for a favour. These mythic connections seem to be late and are not attested before the 3rd century BC. Pergamus' role remained subordinate, although he did receive some cult worship. Beginning in

20800-464: The development of the city. Numerous honorific inscriptions indicate Pasparus' work and his exceptional position in Pergamon at this time. Pergamon still remained a famous city, and was the seat of a conventus (regional assembly). Its neocorate , granted by Augustus , was the first manifestation of the imperial cult in the province of Asia. Pliny the Elder refers to the city as the most important in

21000-425: The difference between motor and sensory nerves , discussed the concept of muscle tone , and explained the difference between agonists and antagonists . Galen's work on animals led to some inaccuracies, most notably his anatomy of the uterus which largely resembled a dog's. Though incorrect in his studies of human reproduction and reproductive anatomy, he came very close to identifying the ovaries as analogous to

21200-456: The discovery of a 1,800-year-old well-preserved geometric patterned floor mosaic around the Red Basilica. The most famous structure from the city is the monumental altar, sometimes called the Great Altar, which was probably dedicated to Zeus and Athena. The foundations are still located in the Upper city, but the remains of the Pergamon frieze, which originally decorated it, are displayed in

21400-400: The dissection of human cadavers since roughly 150 BC. Because of this restriction, Galen performed anatomical dissections on living ( vivisection ) and dead animals, mostly focusing on primates . Galen believed that the anatomical structures of these animals closely mirrored those of humans. Galen clarified the anatomy of the trachea and was the first to demonstrate that the larynx generates

21600-636: The dynastic line as a result of the appropriation of the myth, was not mentioned in the hymn sung in honour of Telephus in the Asclepieion. Otherwise he does not seem to have been paid any heed. But the Pergamenes made offerings to Telephus and the grave of his mother Auge was located in Pergamon near the Caicus. Pergamon thus entered the Trojan epic cycle, with its ruler said to have been an Arcadian who had fought with Telephus against Agamemnon when he landed at

21800-404: The early 19th century that was used for literary and official purposes in the newly formed Greek state. In 1976, Dimotiki was declared the official language of Greece, after having incorporated features of Katharevousa and thus giving birth to Standard Modern Greek , used today for all official purposes and in education . The historical unity and continuing identity between the various stages of

22000-602: The epics of Homer , ancient Greek literature includes many works of lasting importance in the European canon . Greek is also the language in which many of the foundational texts in science and philosophy were originally composed. The New Testament of the Christian Bible was also originally written in Greek. Together with the Latin texts and traditions of the Roman world , the Greek texts and Greek societies of antiquity constitute

22200-411: The epidemic, referring to it as very long lasting, and described its symptoms and his treatment of it. His references to the plague are scattered and brief. Galen was not trying to present a description of the disease so that it could be recognized in future generations; he was more interested in the treatment and physical effects of the disease. For example, in his writings about a young man afflicted with

22400-620: The expansion of the Anatolian beyliks , Pergamon was absorbed into the beylik of Karasids shortly after 1300, and then conquered by the Ottoman beylik . The Ottoman Sultan Murad III had two large alabaster urns transported from the ruins of Pergamon and placed on two sides of the nave in the Hagia Sophia in Istanbul . Pergamon, which traced its founding back to Telephus , the son of Heracles ,

22600-478: The faith of the Pergamon believers, who "dwell where Satan's throne is" is commended by the author . Many scholars believe that the " seat of Satan " refers to the Pergamon Altar, due to its resemblance to a gigantic throne . The well-preserved Theatre of Pergamon  [ de ] dates from the Hellenistic period and had space for around 10,000 people, in 78 rows of seats. At a height of 36 metres, it

22800-718: The first time. As a result of the ongoing Arab threat, the area of settlement retracted to the acropolis , which the Emperor Constans II ( r.  641–668 ) fortified with a 6-meter-thick (20 ft) wall built of spolia . During the middle Byzantine period, the city was part of the Thracesian Theme , and from the time of Leo VI the Wise ( r.  886–912 ) of the Theme of Samos . 7th-century sources attest an Armenian community in Pergamon, probably formed of refugees from

23000-452: The following periods: In the modern era, the Greek language entered a state of diglossia : the coexistence of vernacular and archaizing written forms of the language. What came to be known as the Greek language question was a polarization between two competing varieties of Modern Greek: Dimotiki , the vernacular form of Modern Greek proper, and Katharevousa , meaning 'purified', a compromise between Dimotiki and Ancient Greek developed in

23200-492: The greatest physician of all time. In India many Hindu physicians studied Persian and Urdu languages and learnt Galenic medicine. This trend of studies among Hindu physicians began in the 17th century and lasted until the early 20th century (Speziale 2018). From the 11th century onwards, Latin translations of Islamic medical texts began to appear in the West, alongside the Salerno school of thought, and were soon incorporated into

23400-680: The human body. His anatomical reports remained uncontested until 1543, when printed descriptions and illustrations of human dissections were published in the seminal work De humani corporis fabrica by Andreas Vesalius , where Galen's physiological theory was accommodated to these new observations. Galen's theory of the physiology of the circulatory system remained unchallenged until c.  1242 , when Ibn al-Nafis published his book Sharh tashrih al-qanun li' Ibn Sina ( Commentary on Anatomy in Avicenna's Canon ), in which he reported his discovery of pulmonary circulation . Galen saw himself as both

23600-439: The infinitive entirely (employing a raft of new periphrastic constructions instead) and uses participles more restrictively. The loss of the dative led to a rise of prepositional indirect objects (and the use of the genitive to directly mark these as well). Ancient Greek tended to be verb-final, but neutral word order in the modern language is VSO or SVO. Modern Greek inherits most of its vocabulary from Ancient Greek, which in turn

23800-463: The late 15th century BC, was the first script used to write Greek. It is basically a syllabary , which was finally deciphered by Michael Ventris and John Chadwick in the 1950s (its precursor, Linear A , has not been deciphered and most likely encodes a non-Greek language). The language of the Linear B texts, Mycenaean Greek , is the earliest known form of Greek. Another similar system used to write

24000-622: The late 18th century, these visits were reinforced by a scholarly (especially ancient historical) desire for research, epitomised by Marie-Gabriel-Florent-Auguste de Choiseul-Gouffier , a traveller in Asia Minor and French ambassador to the Sublime Porte in Istanbul from 1784 to 1791. At the beginning of the 19th century, Charles Robert Cockerell produced a detailed account and Otto Magnus von Stackelberg made important sketches. A proper, multi-page description with plans, elevations, and views of

24200-441: The legacy of the city. In 1871, he organised a small expedition there under the leadership of Ernst Curtius . As a result of this short but intensive investigation, two fragments of a great frieze were discovered and transported to Berlin for detailed analysis, where they received some interest, but not a lot. It is not clear who connected these fragments with the Great Altar in Pergamon mentioned by Lucius Ampelius . However, when

24400-500: The lower city as a whole and performed survey work, which increased knowledge of the countryside surrounding the city. In 1971, after a short pause, Wolfgang Radt succeeded him as leader of excavations and directed the focus of research on the residential buildings of Pergamon, but also on technical issues, like the water management system of the city which supported a population of 200,000 at its height. He also carried out conservation projects which were of vital importance for maintaining

24600-478: The main entrance at the southeast corner of the lowest terrace. The lowest and southernmost terrace is small and almost free of buildings. It is known as the Lower Gymnasium and has been identified as the boys' gymnasium. The middle terrace was around 250 metres long and 70 metres wide at the centre. On its north side there was a two-story hall. In the east part of the terrace there was a small prostyle temple in

24800-401: The male testes. Reproduction was a controversial topic in Galen's lifetime, as there was much debate over if the male was solely responsible for the seed, or if the woman was also responsible. Through his vivisection practices, Galen also proved that the voice was controlled by the brain. One of the most famous experiments that he recreated in public was the squealing pig: Galen would cut open

25000-477: The massif falls gradually to the east and south, widening to around 350 metres (1,150 ft) and then descends to the plain towards the southwest. Settlement of Pergamon can be detected as far back as the Archaic period , thanks to modest archaeological finds, especially fragments of pottery imported from the west, particularly eastern Greece and Corinth , which date to the late 8th century BC. Earlier habitation in

25200-638: The material remains of Pergamon. Since 2006, the excavations have been led by Felix Pirson . Most of the finds from the Pergamon excavations before the First World War were taken to the Pergamon Museum in Berlin, with a smaller portion going to the İstanbul Archaeological Museum after it was opened in 1891. After the First World War the Bergama Museum was opened, which has received all finds discovered since then. In May 2022, archaeologists announced

25400-673: The medical field during Galen's lifetime, the main two being the Empiricists and Rationalists (also called Dogmatists or Philosophers), with the Methodists being a smaller group. The Empiricists emphasized the importance of physical practice and experimentation or "active learning" in the medical discipline. In direct opposition to the Empiricists were the Rationalists, who valued the study of established teachings in order to create new theories in

25600-646: The medieval and early modern Islamic Middle East. Job of Edessa is said to have translated 36 of Galen's works into Syriac, some of which were later translated into Arabic by Hunain ibn Ishaq . Galen's approach to medicine became and remains influential in the Islamic world. The first major translator of Galen into Arabic was the Arab Christian Hunayn ibn Ishaq . He translated ( c.  830–870 ) 129 works of "Jalinos" into Arabic . Arabic sources, such as Muhammad ibn Zakarīya al-Rāzi (AD 865–925), continue to be

25800-621: The membership of Greece and Cyprus in the European Union, Greek is one of the organization's 24 official languages . Greek is recognized as a minority language in Albania, and used co-officially in some of its municipalities, in the districts of Gjirokastër and Sarandë . It is also an official minority language in the regions of Apulia and Calabria in Italy. In the framework of the European Charter for Regional or Minority Languages , Greek

26000-415: The mental and the physical. This was a controversial argument at the time, and Galen agreed with some Greek philosophical schools in believing that the mind and body were not separate faculties. He believed that this could be scientifically shown. This was where his opposition to the Stoics became most prevalent. Galen proposed organs within the body to be responsible for specific functions. According to Galen,

26200-441: The modern period. The division into conventional periods is, as with all such periodizations, relatively arbitrary, especially because, in all periods, Ancient Greek has enjoyed high prestige, and the literate borrowed heavily from it. Across its history, the syllabic structure of Greek has varied little: Greek shows a mixed syllable structure, permitting complex syllabic onsets but very restricted codas. It has only oral vowels and

26400-617: The most complete possible exposure and investigation of the historic city and citadel that was possible. He was followed by the architectural historian Wilhelm Dörpfeld from 1900 to 1911, who was responsible for the most important discoveries. Under his leadership the Lower Agora, the House of Attalos, the Gymnasion, and the Sanctuary of Demeter were brought to light. The excavations were interrupted by

26600-451: The most distinctive trait of the Attalids: a pronounced sense of family without rivalry or intrigue - rare amongst the Hellenistic dynasties. Attalus II bore the epithet 'Philadelphos', 'he who loves his brother', and his relations with Eumenes II were compared to the harmony between the mythical brothers Cleobis and Biton . When Attalus III died without an heir in 133 BC, he bequeathed

26800-491: The most influential and wealthy men in Asia. Galen claims that the High Priest chose him over other physicians after he eviscerated an ape and challenged other physicians to repair the damage. When they refused, Galen performed the surgery himself and in so doing won the favor of the High Priest of Asia. Over his four years there, he learned the importance of diet, fitness, hygiene, and preventive measures, as well as living anatomy, and

27000-633: The most loyal supporters of Rome in the Hellenistic world. Attalus I allied with Rome against Philip V of Macedon , during the first and second Macedonian Wars . In the Roman–Seleucid War , Pergamon joined the Romans' coalition against Antiochus III , and was rewarded with almost all the former Seleucid domains in Asia Minor at the Peace of Apamea in 188 BC. The kingdom's territories thus reached their greatest extent. Eumenes II supported Rome again in

27200-490: The myth, the Attalids stood within the tradition of the other, older Hellenistic dynasties, who legitimized themselves through divine descent, and sought to increase their own prestige. The inhabitants of Pergamon enthusiastically followed their lead and took to calling themselves Telephidai ( Τηλεφίδαι ) and referring to Pergamon itself in poetic registers as the 'Telephian city' ( Τήλεφις πόλις ). The first mention of Pergamon in written records after ancient times comes from

27400-483: The name of medical advancements. The Methodists formed somewhat of a middle ground, as they were not as experimental as the Empiricists, nor as theoretical as the Rationalists. The Methodists mainly utilized pure observation, showing greater interest in studying the natural course of ailments than making efforts to find remedies. Galen's education had exposed him to the five major schools of thought (Platonists, Peripatetics, Stoics, Epicureans, Pyrrhonists), with teachers from

27600-405: The nervous system. Galen went on to be the first physician to study what happens when the spinal cord is transected on multiple different levels. He worked with pigs and studied their neuroanatomy by severing different nerves either totally or partially to see how it affected the body. He even dealt with diseases affecting the spinal cord and nerves. In his work De motu musculorum , Galen explained

27800-579: The north fighting the Marcomanni . During the autumn of 169 when Roman troops were returning to Aquileia , a great plague, most likely one of the first appearances of smallpox (then referred to as the Antonine Plague ) in the Mediterranean world, broke out, and the emperor summoned Galen back to Rome. He was ordered to accompany Marcus and Verus to Germany as the court physician. The following spring Marcus

28000-454: The north side, the rock forms a 70 metres (230 ft) wide spur of rock. To the southeast of this spur, which is known as the 'Garden of the Queen', the massif reaches its greatest height and breaks off suddenly immediately to the east. The upper city extends for another 250 metres (820 ft) to the south, but it remains very narrow, with a width of only 150 metres (490 ft). At its south en d

28200-461: The northern end was unimpeded. A marble stage building was only built in the 1st century BC. Additional theatres were built in the Roman period, one in the Roman new city and the other in the sanctuary of Asclepius. On the highest point of the citadel is the Temple of Trajan , the Traianeum or Trajaneum. The Temple is also called the Temple of Zeus Philios , as both Zeus and Trajan were worshiped in

28400-500: The northern stoa, which is probably of Roman date and a large banquet hall in the centre. Further rooms of uncertain function were accessible from the stoas. In the west was a south-facing Ionic antae temple , the central sanctuary of the gymnasium. The eastern area was replaced with a bath complex in Roman times. Further Roman baths were constructed to the west of the Ionic temple. The sanctuary of Hera Basileia ('the Queen') lay north of

28600-399: The noun they modify and relative pronouns are clause-initial. However, the morphological changes also have their counterparts in the syntax, and there are also significant differences between the syntax of the ancient and that of the modern form of the language . Ancient Greek made great use of participial constructions and of constructions involving the infinitive, and the modern variety lacks

28800-521: The objects of study of the discipline of Classics . During antiquity , Greek was by far the most widely spoken lingua franca in the Mediterranean world . It eventually became the official language of the Byzantine Empire and developed into Medieval Greek . In its modern form , Greek is the official language of Greece and Cyprus and one of the 24 official languages of the European Union . It

29000-706: The older periods of Greek, loanwords into Greek acquired Greek inflections, thus leaving only a foreign root word. Modern borrowings (from the 20th century on), especially from French and English, are typically not inflected; other modern borrowings are derived from Albanian , South Slavic ( Macedonian / Bulgarian ) and Eastern Romance languages ( Aromanian and Megleno-Romanian ). Greek words have been widely borrowed into other languages, including English. Example words include: mathematics , physics , astronomy , democracy , philosophy , athletics , theatre, rhetoric , baptism , evangelist , etc. Moreover, Greek words and word elements continue to be productive as

29200-465: The original Greek, although many were destroyed and some credited to him are believed to be spurious. Although there is some debate over the date of his death, he was no younger than seventy when he died. Galen's Greek name Γαληνός ( Galēnós ) comes from the adjective γαληνός ( galēnós ) 'calm'. Galen's Latin name (Aelius or Claudius) implies he had Roman citizenship . Galen describes his early life in On

29400-490: The plague, he concentrated on the treatment of internal and external ulcerations. According to Niebuhr, "this pestilence must have raged with incredible fury; it carried off innumerable victims. The ancient world never recovered from the blow inflicted upon it by the plague that visited it in the reign of M. Aurelius." The mortality rate of the plague was 7–10 percent; the outbreak in 165–168 would have caused approximately 3.5 to 5 million deaths. Otto Seeck believes that over half

29600-478: The pleasures of the body and was moved by feelings of enjoyment. This third part of the soul is the animalistic, or more natural, side of the soul; it deals with the natural urges of the body and survival instincts. Galen proposed that when the soul is moved by too much enjoyment, it reaches states of "incontinence" and "licentiousness", the inability to willfully cease enjoyment, which was a negative consequence of too much pleasure. In order to unite his theories about

29800-509: The population of the empire perished. J. F. Gilliam believes that the Antonine plague probably caused more deaths than any other epidemic during the empire before the mid-3rd century. Although Galen's description is incomplete, it is sufficient to enable a firm identification of the disease as related to smallpox . Galen notes that the exanthema covered the victim's entire body and was usually black. The exanthem became rough and scabby where there

30000-546: The previous few years and had discovered for example the architrave inscription of the Temple of Demeter in 1875, was entrusted with carry out work in the area of the altar of Zeus in 1878, where he continued to work until 1886. With the approval of the Ottoman Empire , the reliefs discovered there were transported to Berlin, where the Pergamon Museum was opened for them in 1907. The work was continued by Conze, who aimed for

30200-406: The province and the local aristocracy continued to reach the highest circles of power in the 1st century AD, like Aulus Julius Quadratus who was consul in 94 and 105. Yet it was only under Trajan and his successors that a comprehensive redesign and remodelling took place, with the construction of a Roman 'new city' at the base of the Acropolis. The city was the first in the province to receive

30400-422: The rational soul. The functions of "growing or being alive" resided in the spirited soul. The spirited soul also contained our passions, such as anger. These passions were considered to be even stronger than regular emotions, and, as a consequence, more dangerous. The third part of the soul, or the appetitive spirit, controlled the living forces in our body, most importantly blood. The appetitive spirit also regulated

30600-497: The rise of the city; the story that it was invented by the Pergamenes, to circumvent the Ptolemies ' monopoly on papyrus production, is not true. Surviving epigraphic documents show how the Attalids supported the growth of towns by sending in skilled artisans and by remitting taxes. They allowed the Greek cities in their domains to maintain nominal independence, and sent gifts to Greek cultural sites like Delphi , Delos , and Athens. The two brothers Eumenes II and Attalus II displayed

30800-426: The sick would come to seek the ministrations of the priesthood. Romans frequented the temple at Pergamon in search of medical relief from illness and disease. It was also the haunt of notable people such as the historian Claudius Charax, the orator Aelius Aristides , the sophist Polemo , and the consul Cuspius Rufinus . Galen's father died in 148, leaving Galen independently wealthy at the age of 19. He then followed

31000-488: The site of a large temple to the healing god Asclepius . The city attracted both Stoic and Platonic philosophers, to whom Galen was exposed at age 14. His studies also took in each of the principal philosophical systems of the time, including Aristotelian and Epicurean . His father had planned a traditional career for Galen in philosophy or politics and took care to expose him to literary and philosophical influences. However, Galen states that in around 145 his father had

31200-439: The soul and how it operated within the body, he adapted the theory of the pneuma , which he used to explain how the soul operated within its assigned organs, and how those organs, in turn, interacted together. Galen then distinguished the vital pneuma , in the arterial system, from the psychic pneuma , in the brain and nervous system. Galen placed the vital pneuma in the heart and the psychic pneuma ( spiritus animalis ) within

31400-478: The soul as having one part, which was the rational soul and they claimed it would be found in the heart. Galen, following Plato's idea, came up with two more parts to the soul. Galen also rejected Stoic propositional logic and instead embraced a hypothetical syllogistic which was strongly influenced by the Peripatetics and based on elements of Aristotelian logic. Galen believed there is no sharp distinction between

31600-438: The soul. Plato believed that the body and the soul were separate entities, rivaling the Stoics. Plato proclaimed that the soul is immortal, so it must exist before one is born, beyond the human body. This influenced Galen's thinking that the soul had to be acquired because the soul does not always reside within the human body. Plato's influence in Galen's model showed itself most prominently in what Galen dubbed arterial blood, which

31800-610: The source of discovery of new or relatively inaccessible Galenic writings. One of Hunayn's Arabic translations, Kitab ila Aglooqan fi Shifa al Amrad , which is extant in the Library of Ibn Sina Academy of Medieval Medicine & Sciences , is regarded as a masterpiece of Galen's literary works. A part of the Alexandrian compendium of Galen's work, this 10th-century manuscript comprises two parts that include details regarding various types of fevers (Humyat) and different inflammatory conditions of

32000-437: The stressed vowel; the so-called breathing marks ( rough and smooth breathing ), originally used to signal presence or absence of word-initial /h/; and the diaeresis , used to mark the full syllabic value of a vowel that would otherwise be read as part of a diphthong. These marks were introduced during the course of the Hellenistic period. Actual usage of the grave in handwriting saw a rapid decline in favor of uniform usage of

32200-479: The study of Galen and other Greek works almost disappeared in the Latin West. In contrast, in the predominantly Greek-speaking eastern half of the Roman empire (Byzantium), many commentators of the subsequent centuries, such as Oribasius , physician to the emperor Julian who compiled a Synopsis in the 4th century, preserved and disseminated Galen's works, making them more accessible. Nutton refers to these authors as

32400-546: The subject and in his demonstrations and public disputations. Galen's work on anatomy remained largely unsurpassed and unchallenged up until the 16th century in Europe. In the middle of the 16th century, the anatomist Andreas Vesalius challenged the anatomical knowledge of Galen by conducting dissections on human cadavers. These investigations allowed Vesalius to refute aspects of Galen's theories regarding anatomy. Galen's interest in human anatomy ran afoul of Roman law that prohibited

32600-405: The temple are unfluted and retained bossage , but it is not clear whether this was a result of carelessness or incompleteness. A two-story stoa surrounding the temple on three sides was added under Eumenes II, along with the propylon in the southeast corner, which is now found, largely reconstructed, in the Pergamon Museum in Berlin. The balustrade of the upper level of the north and east stoas

32800-478: The three attacks of quartan ague, and the doctors had given him up, as it was now mid-winter." Some Roman physicians criticized Galen for his use of the prognosis in his treatment of Eudemus. This practice conflicted with the then-current standard of care , which relied upon divination and mysticism . Galen retaliated against his detractors by defending his own methods. Garcia-Ballester quotes Galen as saying: "In order to diagnose, one must observe and reason." This

33000-595: The time of Galen. The most important translator of Galen's works into Latin was Niccolò di Deoprepio da Reggio, who spent several years working on Galen. Niccolò worked at the Angevin Court during the reign of king Robert of Naples . Among Niccolò's translations is a piece from a medical treatise by Galen, of which the original text is lost. Greek language Greek ( Modern Greek : Ελληνικά , romanized :  Elliniká , [eliniˈka] ; Ancient Greek : Ἑλληνική , romanized :  Hellēnikḗ )

33200-558: The title of Doubts on Galen by al-Rāzi implies, as well as the writings of physicians such as Ibn Zuhr and Ibn al-Nafis , the works of Galen were not accepted unquestioningly, but as a challengeable basis for further inquiry . A strong emphasis on experimentation and empiricism led to new results and new observations, which were contrasted and combined with those of Galen by writers such as al-Rāzi, Ali ibn Abbas al-Majusi , Abu al-Qasim al-Zahrawi , Ibn Sina (Avicenna), Ibn Zuhr, and Ibn al-Nafis. For example, Ibn al-Nafis' discovery of

33400-511: The tomb of Galenus in Palermo was still well preserved in the tenth century. Nutton believes that "On Theriac to Piso" is genuine, that the Arabic sources are correct, and that the Suda has erroneously interpreted the 70 years of Galen's career in the Arabic tradition as referring to his whole lifespan. Boudon-Millot more or less concurs and favors a date of 216. Galen contributed a substantial amount to

33600-423: The treatment of fractures and severe trauma, referring to their wounds as "windows into the body". Only five deaths among the gladiators occurred while he held the post, compared to sixty in his predecessor's time, a result that is in general ascribed to the attention he paid to their wounds. At the same time he pursued studies in theoretical medicine and philosophy. Galen went to Rome in 162 and made his mark as

33800-864: The understanding of pathology. Under the Hippocratic bodily humors theory, differences in human moods come as a consequence of imbalances in one of the four bodily fluids : blood, yellow bile, black bile, and phlegm. Galen promoted this theory and the typology of human temperaments . In Galen's view, an imbalance of each humor corresponded with a particular human temperament (blood – sanguine, black bile – melancholic, yellow bile – choleric, and phlegm – phlegmatic). Thus, individuals with sanguine temperaments are extroverted and social; choleric people have energy, passion, and charisma; melancholics are creative, kind, and considerate; and phlegmatic temperaments are characterised by dependability, kindness, and affection. Galen

34000-412: The unity of the two subjects and their views. Using their theories, combined with Aristotle's, Galen developed a tripartite soul consisting of similar aspects. He used the same terms as Plato , referring to the three parts as rational, spiritual, and appetitive. Each corresponded to a localized area of the body. The rational soul was in the brain, the spiritual soul was in the heart, and the appetitive soul

34200-408: The upper terrace of the gymnasium. Its structure sits on two parallel terraces, the south one about 107.4 metres above sea level and the north one about 109.8 metres above sea level. The Temple of Hera sat in the middle of the upper terrace, facing to the south, with a 6-metre-wide (20 ft) exedra to the west and a building whose function is very unclear to the east. The two terraces were linked by

34400-466: The voice. In one experiment, Galen used bellows to inflate the lungs of a dead animal. Galen's research on physiology was largely influenced by previous works of philosophers Plato and Aristotle, as well as from the physician Hippocrates. He was one of the first people to use experiments as a method of research for his medical findings. Doing so allowed him to explore various parts of the body and its functions. Among Galen's major contributions to medicine

34600-401: The whole of Pergamon to Rome. This was challenged by Aristonicus , who claimed to be Attalus III's brother and led an armed uprising against the Romans with the help of Blossius , a famous Stoic philosopher . For a period he enjoyed success, defeating and killing the Roman consul P. Licinius Crassus and his army, but he was defeated in 129 BC by the consul M. Perperna . The Attalid kingdom

34800-419: The work of his predecessors, and it is in Galen's words (Galenism) that Greek medicine was handed down to subsequent generations, such that Galenism became the means by which Greek medicine was known to the world. Often, this was in the form of restating and reinterpreting, such as in Magnus of Nisibis' 4th-century work on urine, which was in turn translated into Arabic. Yet the full importance of his contributions

35000-515: Was a distinct dialect of Greek itself. Aside from the Macedonian question, current consensus regards Phrygian as the closest relative of Greek, since they share a number of phonological, morphological and lexical isoglosses , with some being exclusive between them. Scholars have proposed a Graeco-Phrygian subgroup out of which Greek and Phrygian originated. Among living languages, some Indo-Europeanists suggest that Greek may be most closely related to Armenian (see Graeco-Armenian ) or

35200-421: Was a physiological basis for mental disorders. Galen connected many of his theories to the pneuma and he opposed the Stoics ' definition of and use of the pneuma . The Stoics, according to Galen, failed to give a credible answer for the localization of functions of the psyche, or the mind. Through his use of medicine, he was convinced that he came up with a better answer, the brain. The Stoics only recognized

35400-478: Was added to the UNESCO World Heritage List in 2014. Pergamon lies on the north edge of the Caicus plain in the historic region of Mysia in the northwest of Turkey. The Caicus river breaks through the surrounding mountains and hills at this point and flows in a wide arc to the southwest. At the foot of the mountain range to the north, between the rivers Selinus and Cetius, there is the massif of Pergamon which rises 335 metres (1,099 ft) above sea level. The site

35600-404: Was also a pioneer in research about the human spine. His dissections and vivisections of animals led to key observations that helped him accurately describe the human spine, spinal cord , and vertebral column . Galen also played a major role in the discoveries of the central nervous system . He was also able to describe the nerves that emerge from the spine, which is integral to his research about

35800-413: Was also a skilled surgeon, operating on human patients. Many of his procedures and techniques would not be used again for centuries, such as the procedures he performed on brains and eyes. His surgical experiments included ligating the arteries of living animals. Although many 20th-century historians have claimed that Galen believed the lens to be in the exact center of the eye, Galen actually understood that

36000-423: Was also used as the official language of government and religion in the Christian Nubian kingdoms , for most of their history. Greek, in its modern form, is the official language of Greece, where it is spoken by almost the entire population. It is also the official language of Cyprus (nominally alongside Turkish ) and the British Overseas Territory of Akrotiri and Dhekelia (alongside English ). Because of

36200-442: Was also used in Ancient Greek. Greek has occasionally been written in the Latin script , especially in areas under Venetian rule or by Greek Catholics . The term Frankolevantinika / Φραγκολεβαντίνικα applies when the Latin script is used to write Greek in the cultural ambit of Catholicism (because Frankos / Φράγκος is an older Greek term for West-European dating to when most of (Roman Catholic Christian) West Europe

36400-422: Was decorated with reliefs depicting weapons which commemorated Eumenes II's military victory. The construction mixed Ionic columns and Doric triglyphs (of which five triglyphs and metopes survive). In the area of the sanctuary, Attalos I and Eumenes II constructed victory monuments, most notably the Gallic dedications. The northern stoa seems to have been the site of the Library of Pergamon. The Library of Pergamon

36600-472: Was divided between Rome, Pontus , and Cappadocia , with the bulk of its territory becoming the new Roman province of Asia . The city itself was declared free and served briefly as capital of the province, before this distinction was transferred to Ephesus . In 88 BC, Mithridates VI Eupator made Pergamon his headquarters in his first war against Rome, in which he was defeated. The victorious Romans deprived Pergamon of all its benefits and of its status as

36800-414: Was expanded into a lavish spa. This sanctuary grew in fame and was considered one of the most famous healing centers of the Roman world. In the middle of the 2nd century Pergamon was one of the largest cities in the province, and had around 200,000 inhabitants. Galen , the most famous physician of antiquity aside from Hippocrates , was born at Pergamon and received his early training at the Asclepieion. At

37000-460: Was given the position of personal physician to several emperors . Galen's understanding of anatomy and medicine was principally influenced by the then-current theory of the four humors : black bile, yellow bile, blood, and phlegm, as first advanced by the author of On the Nature of Man in the Hippocratic corpus . Galen's views dominated and influenced Western medical science for more than 1,300 years. His anatomical reports were based mainly on

37200-444: Was his work on the circulatory system . He was the first to recognize that there are distinct differences between venous (dark) and arterial (bright) blood. In addition to these discoveries, Galen postulated much more about the nature of the circulatory system . He believed that blood originated in the liver, which follows the teachings of Hippocrates. The liver converted nutrients gathered from ingested food into blood to be used in

37400-438: Was in the liver. Galen was the first scientist and philosopher to assign specific parts of the soul to locations in the body because of his extensive background in medicine. This idea is now referred to as localization of function. Galen's assignments were revolutionary for the time period, which set the precedent for future localization theories. Galen believed each part of this tripartite soul controlled specific functions within

37600-407: Was named after Marcus Aurelius' family name of Antoninus. It was also known as the Plague of Galen and held an important place in medicinal history because of its association with Galen. He had first-hand knowledge of the disease, and was present in Rome when it first struck in 166, and was also present in the winter of 168–69 during an outbreak among troops stationed at Aquileia. He had experience with

37800-426: Was no ulceration. He states that those who were going to survive developed a black exanthem. According to Galen, it was black because of a remnant of blood putrefied in a fever blister that was pustular. His writings state that raised blisters were present in the Antonine plague, usually in the form of a blistery rash. Galen states that the skin rash was close to the one Thucydides described. Galen describes symptoms of

38000-407: Was not appreciated until long after his death. Galen's rhetoric and prolificity were so powerful as to convey the impression that there was little left to learn. The term Galenism has subsequently taken on both a positive and pejorative meaning as one that transformed medicine in late antiquity yet so dominated subsequent thinking as to stifle further progress. After the collapse of the Western Empire

38200-404: Was part of Greek culture, and Syrian Christians came in contact with it while the Eastern Roman Empire (Byzantium) ruled Syria and western Mesopotamia, regions that were conquered in the 7th century by the Arabs . After 750, these Syrian Christians made the first translations of Galen into Syriac and Arabic . From then on, Galen and the Greek medical tradition in general became assimilated into

38400-523: Was persuaded to release Galen after receiving a report that Asclepius was against the project. He was left behind to act as physician to the imperial heir Commodus . It was here in court that Galen wrote extensively on medical subjects. Ironically, Lucius Verus died in 169, and Marcus Aurelius himself died in 180, both victims of the plague. Galen was the physician to Commodus for much of the emperor's life and treated his common illnesses. According to Dio Cassius 72.14.3–4, in about 189, under Commodus' reign,

38600-497: Was planning an expedition against the Persian satraps Tissaphernes and Pharnabazus , at this location in March 399 BC. At this time Pergamon was in the possession of the family of Gongylos from Eretria , a Greek favourable to the Achaemenid Empire who had taken refuge in Asia Minor and obtained the territory of Pergamon from Xerxes I , and Xenophon was hosted by his widow Hellas. In 362 BC, Orontes , satrap of Mysia, used Pergamon as his base for an unsuccessful revolt against

38800-408: Was surrounded by simple ashlar walls, until further stoas were inserted in Hadrian's reign. During the excavations fragments of statues of Trajan and Hadrian were found in the rubble of the cella , including their portrait heads , as well as fragments of the cult statue of Zeus Philios. At Pergamon, Dionysus had the epithet Kathegemon , 'the guide', and was already worshiped in the last third of

39000-418: Was the basis of his criticism of the doctors who proceeded alogos and askeptos." However, Eudemus warned Galen that engaging in conflict with these physicians could lead to his assassination. "Eudemus said this, and more to the same effect; he added that if they were not able to harm me by unscrupulous conduct they would proceed to attempts at poisoning. Among other things he told me that, some ten years before,

39200-401: Was the heart and the arteries, which Galen believed to be responsible for providing life-giving energy. The last theorized system was the liver and veins, which Galen theorized were responsible for nutrition and growth. Galen also theorized that blood was made in the liver and sent out around the body. One of Galen's major works, On the Doctrines of Hippocrates and Plato , sought to demonstrate

39400-403: Was the second largest in the ancient Greek world after the Library of Alexandria , containing at least 200,000 scrolls. The location of the library building is not certain. Since the 19th century excavations, it has generally been identified with an annex of the northern stoa of the sanctuary of Athena in the Upper Citadel, which was built by Eumenes II. Inscriptions in the gymnasium which mention

39600-451: Was to create a second Athens , a cultural and artistic hub of the Greek world. They remodeled their Acropolis after the Acropolis in Athens, and the Library of Pergamon was renowned as second only to the Library of Alexandria . Pergamon was also a flourishing center for the production of parchment , whose name is a corruption of pergamenos , meaning "from Pergamon". Despite this etymology, parchment had been used in Asia Minor long before

39800-453: Was under the control of the Frankish Empire ). Frankochiotika / Φραγκοχιώτικα (meaning 'Catholic Chiot') alludes to the significant presence of Catholic missionaries based on the island of Chios . Additionally, the term Greeklish is often used when the Greek language is written in a Latin script in online communications. The Latin script is nowadays used by the Greek-speaking communities of Southern Italy . The Yevanic dialect

40000-450: Was written by Romaniote and Constantinopolitan Karaite Jews using the Hebrew Alphabet . In a tradition, that in modern time, has come to be known as Greek Aljamiado , some Greek Muslims from Crete wrote their Cretan Greek in the Arabic alphabet . The same happened among Epirote Muslims in Ioannina . This also happened among Arabic-speaking Byzantine rite Christians in the Levant ( Lebanon , Palestine, and Syria ). This usage

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