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50-424: Located to the southeast of Leiden and north of Zoetermeer , the municipality of Zoeterwoude consists of Gelderswoude , Weipoort , Westeinde , Zoeterwoude-Dorp , Zoeterwoude-Rijndijk and Zuidbuurt . [REDACTED] Dutch topographic map of Zoeterwoude, Sept. 2014. Click to enlarge. The name Zoeterwoude is first mentioned in a document from 1205, which references a certain "Florentius van Sotrewold". It

100-407: A catastrophe struck the city when a boat loaded with 17,400 kg (38,360 lb) of gunpowder blew up in the middle of Leiden. 151 people were killed, over 2,000 were injured and some 220 homes were destroyed. King Louis Bonaparte personally visited the city to provide assistance to the victims. Although located in the centre of the city, the area destroyed remained empty for many years. In 1886

150-563: A L st god den heer V erdroot gaf h I V ns W eder broot zo V ee L WI CV nsten W ens C hen. (Dutch: "When the Black Famine had brought to the death nearly six thousand persons, then God the Lord repented, and gave bread again as much as we could wish".) Zorg en Zekerheid Leiden is the basketball club of Leiden. In 2011, 2013 and 2021 they won the National Title, in 2010 and 2012

200-625: A business continued by his descendants through 1712. In 1572, the city sided with the Dutch Revolt against Spanish rule and played an important role in the Eighty Years' War . It was besieged from May to October 1574 by the Spanish but was relieved by the cutting of the dikes, thus enabling ships to carry provisions to the inhabitants. William I of Orange founded the University of Leiden in 1575 as

250-553: A reward for their heroic defense. The end of the siege is still celebrated in Leiden on October 3 each year. According to tradition, the citizens of Leiden were offered the choice between a university and a certain exemption from taxes and chose the university. The siege is notable also for being the first instance in Europe of the issuance of paper money, with paper taken from prayer books being stamped using coin dies when silver ran out. Leiden

300-521: A separate museum called the SieboldHuis . The Bibliotheca Thysiana occupies an old Renaissance building of the year 1655. It is especially rich in legal works and vernacular chronicles. Noteworthy are also the many special collections at Leiden University Library among which those of the Society of Dutch Literature (1766) and the collection of casts and engravings. In recent years the university has built

350-593: A signatory to the Berne Convention for the Protection of Literary and Artistic Works . He felt that international copyright restrictions would stifle the Dutch publishing industry. Leiden began to expand beyond its 17th-century moats around 1896 and the number of citizens surpassed 50,000 in 1900. After 1920, new industries were established in the city, such as the canning and metal industries. During World War II , Leiden

400-399: Is a city and municipality in the province of South Holland , Netherlands . The municipality of Leiden has a population of 127,046 (31 January 2023), but the city forms one densely connected agglomeration with its suburbs Oegstgeest , Leiderdorp , Voorschoten and Zoeterwoude with 215,602 inhabitants. The Netherlands Central Bureau of Statistics (CBS) further includes Katwijk in

450-530: Is known as the place where the Pilgrims and some of the settlers of New Amsterdam lived, operating a printing press for a time in the early 17th century before their departure to Massachusetts and New Amsterdam in the New World . Leiden prospered in the 17th century, in part because of the impetus to the textile industry by refugees from Flanders . The city had lost about a third of its 15,000 citizens during

500-438: Is located in Leiden, Netherlands. LUMC is a modern university medical center for research, education and patient care. Its research practice ranges from pure fundamental medical research to applied clinical research. The hospital has clinical departments of all medical specialties, and acts as a tertiary referral centre for the northern part of the province of South Holland . Special units include: The LUMC aims at identifying

550-514: Is named after the mayor Pieter Adriaansz. van der Werff  [ nl ] , who defended the city against the Spaniards in 1574. The city was beleaguered for months and many died from famine. The open space for the park was formed by the accidental explosion of a ship loaded with gunpowder in 1807, which destroyed hundreds of houses, including that of the Elsevier family of printers . Because of

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600-636: Is part of the PREVENT-nCoV consortium comprising ExpreS2ion Biotechnologies , AdaptVac (a joint-venture between ExpreS2ion Biotechnologies and the University of Copenhagen spin-out NextGen Vaccines), the Institute for Tropical Medicine Tübingen , The Department of Immunology and Microbiology (ISIM) at the University of Copenhagen, and the Laboratory of Virology at Wageningen University and Research . In March 2020

650-461: Is seen as a joint responsibility of students and professors and a critical scientific attitude and curiosity are valued highly. Enjoying studies and student life is also considered to be important. LUMC offers the following university courses: LUMC also offers continuing education and training for doctors, scientists and other healthcare professionals. Continuing education is organized by the departments Boerhaave Nascholing and Educatie Zorgsector. In

700-499: Is uncertain if this is a reference to the village. The first confirmed existence is from 1276 when Dirk van Santhorst received the "Soetrewold" fiefdom from Floris V, Count of Holland . Its municipal boundaries were set circa 1300. At that time it was one of the largest municipalities in the Netherlands, but later much land was annexed by surrounding cities, notably Leiden . In 1450, the first bridge between Leiderdorp and Zoeterwoude

750-697: The Stedelijk Museum De Lakenhal (the municipal museum of fine arts), and the Bibliotheca Thysiana . The growing city needed another church and the Marekerk was the first Protestant church to be built in Leiden (and in Holland) after the Reformation . It is an example of Dutch Classicism . In the drawings by Van 's Gravesande the pulpit is the centrepiece of the church. The pulpit is modelled after

800-526: The Leiden Bio Science Park at the city's outskirts to accommodate the Science departments. Bus transport in Leiden is provided by Arriva . Railway stations within the municipality of Leiden are: The following is a selection of important Leidenaren throughout history: Leiden is twinned with: Nae z W arte H V nger-noot Gebra C ht had tot de doot b I naest zes-d VI zent M ens C hen;

850-633: The Morspoort , both dating from the end of the 17th century. Apart from one small watch tower on the Singel nothing is left of the town's city walls . Another former fortification is the Gravensteen . Built as a fortress in the 13th century it has since served as house, library and prison. Presently it is one of the university's buildings. The chief of Leiden's numerous churches are the Hooglandse Kerk (or

900-526: The Oude Rijn , which enter Leiden on the east, unite in the centre of the city. The city is further intersected by numerous small canals with tree-bordered quays . On the west side of the city, the Hortus Botanicus and other gardens extend along the old Singel , or outer canal. The Leidse Hout park, which contains a small deer park, lies on the northwest border with Oegstgeest . The Van der Werf Park

950-515: The Dutch Constitution in April 1848 in his house at Garenmarkt 9 in Leiden. Leiden's reputation as the "city of books" continued through the 19th century with the establishment of publishing dynasties by Evert Jan Brill and Albertus Willem Sijthoff . Sijthoff, who rose to prominence in the trade of translated books, wrote a letter in 1899 to Queen Wilhelmina regarding his opposition to becoming

1000-567: The Kaag Lakes ( Kagerplassen ) lies just to the northeast of Leiden. A university city since 1575, Leiden has been one of Europe 's most prominent scientific centres for more than four centuries. University buildings are scattered throughout the city and the many students from all over the world give the city a bustling, vivid and international atmosphere. Many important scientific discoveries have been made here, giving rise to Leiden's motto: 'City of Discoveries'. The city houses Leiden University ,

1050-637: The National Cup and in 2011 and 2012 the National Super Cup. The club also played in the FIBA EuroChallenge and reached the Second Round (Best 16) in 2011/2012. Leiden University Medical Center Leiden University Medical Center (Dutch: Leids Universitair Medisch Centrum ) or LUMC is the university hospital affiliated with Leiden University , of which it forms the medical faculty . It

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1100-432: The agglomeration which makes the total population of the Leiden urban agglomeration 282,207 and in the larger Leiden urban area also Teylingen , Noordwijk , and Noordwijkerhout are included with in total 365,913 inhabitants. Leiden is located on the Oude Rijn , at a distance of some 20 km (12 mi) from The Hague to its south and some 40 km (25 mi) from Amsterdam to its north. The recreational area of

1150-405: The castles of Poelgeest, Ter Does, Hoichmade, de Zijl, ter Waerd, Warmond and de Paddenpoel. On 24 June the army appeared before the walls of Leiden. On 17 August 1420, after a two-month siege, the city surrendered to John of Bavaria. The burgrave Filips of Wassenaar was stripped of his offices and rights and lived out his last years in captivity. Leiden flourished in the 16th and 17th century. At

1200-525: The causes of disease, improving diagnosis, prevention, and ultimately developing effective treatments. Within LUMC different specialists work together around research themes. Combining cross-border expertise may solve biomedical problems and bring answers not found when working in a stand-alone fashion. The themes are: LUMC offers a large range of education and hosts the Faculty of Medicine of Leiden University. Education

1250-432: The centuries. After World War II, fundamental research became an increasingly important task of Leiden University's Faculty of Medicine. The Biomedical Science study programme is an expression of this. In patient care, high technology treatments have come in the place of admissions lasting weeks or months. The many years of collaboration between the university and the teaching hospital acquired greater permanence in 1996 when

1300-460: The church of St Pancras , built in the 15th century and containing a monument to Pieter Adriaansz. van der Werff) and the Pieterskerk (church of St Peter (1315)) with monuments to Scaliger , Boerhaave and other famous scholars. From a historical perspective the Marekerk is interesting too. Arent van 's Gravesande designed that church in 1639. Other fine examples of his work in Leiden are in

1350-420: The close of the 15th century, the weaving establishments of Leiden (mainly broadcloth ) were very important. In the same period, Leiden developed an important printing and publishing industry. Printers Lucas van Leyden and Otto van Veen lived here, and so did Christoffel Plantijn . One of Christoffel's pupils was Lodewijk Elzevir (1547–1617), who established the largest bookshop and printing works in Leiden,

1400-457: The course of two to three days and includes parades, a hutspot feast, historical reenactments, a funfair and other events. Since 2006, the city has also hosted the annual Leiden International Film Festival . Leiden has important functions as a shopping and trade centre for communities around the city. The city also houses the Eurotransplant , the international organization responsible for

1450-496: The decline of the textile industries. The baize manufacture was given up at the beginning of the 19th century, although industry remained central to Leiden economy. This decline can be seen in the fall in population, which had sunk to 30,000 between 1796 and 1811, and in 1904 was 56,044. Leiden was the publishing place from the 17th to the early 19th century of the important journal Nouvelles Extraordinaires de Divers Endroits , known also as Gazette de Leyde . On 12 January 1807,

1500-461: The early 18th century in Leiden with Boerhaave. Leiden is a city with a rich cultural heritage, not only in science, but also in the arts. One of the world's most famous painters, Rembrandt , was born and educated in Leiden. Other Leiden painters include Lucas van Leyden , Jan van Goyen and Jan Steen . Leiden was formed on an artificial hill (today called the Burcht van Leiden ) at the confluence of

1550-413: The economic decline from the end of the 17th until the middle of the 19th century, much of the 16th- and 17th-century city centre is still intact. It is the second largest 17th-century town centre in the Netherlands, the largest being Amsterdam's city centre. A hundred buildings in the centre are decorated with large murals of poetry, part of a wall poem project active from 1992, and still ongoing. At

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1600-426: The first time (1908) and later managed to reach a temperature of less than one degree above the absolute minimum . Albert Einstein also spent some time at Leiden University during his early to middle career. The city's biggest and most popular annual festival is celebrated on 3 October and is called simply 3 Oktober . The people of Leiden celebrate the end of the Spanish siege of 1574. It typically takes place over

1650-407: The hospital and medical faculty merged to form Leiden University Medical Center, with patient care, instruction, study programmes, continuing education and research as its five core tasks. The opening of two new buildings on 1 December 2006 was the fulfilment of a wish of long standing: all the core tasks are now under one roof. The various buildings are linked by skyways and tunnels, thus symbolising

1700-467: The interrelationship of the core tasks. In 2016 Leiden University Medical Centre founded a branch at Campus The Hague , with research, teaching and a training programme for GPs . In 2023 the LUMC was formally accused of fraud by the European Union in seven studies. Dean Pancras Hogendoorn stepped down because of the investigation which is currently in progress. Leiden University Medical Center

1750-462: The mediation and allocation of organ donation procedures in Austria, Belgium, Croatia, Germany, Luxembourg, the Netherlands and Slovenia. Leiden also houses the headquarters of Airbus , a global pan-European aerospace and defence corporation and a leading defence and military contractor worldwide. The group includes Airbus , the leading manufacturer of commercial aircraft worldwide. The two branches of

1800-670: The oldest university of the Netherlands, and Leiden University Medical Center . Leiden University is one of Europe's top universities, with thirteen Nobel Prize winners. It is a member of the League of European Research Universities and positioned highly in all international academic rankings. It is twinned with Oxford , the location of the United Kingdom's oldest university . Leiden University and Leiden University of Applied Sciences ( Leidse Hogeschool ) together have around 35,000 students. Modern scientific medical research and teaching started in

1850-581: The one in the Nieuwe Kerk at Haarlem (designed by Jacob van Campen ). The building was first used in 1650, and is still in use. The Heilige Lodewijkkerk is first catholic church in Leiden that was built after the Reformation. This church was given to the Catholics after the gunpowder explosion in 1807, which killed 150 inhabitants and destroyed a large part of the city centre. The 'Waalse Kerk' (Breestraat 63)

1900-465: The other local noblemen of the Hook faction assumed that the duke would besiege Leiden first and send small units out to conquer the surrounding citadels. But John of Bavaria chose to attack the citadels first. He rolled the cannons along with his army but one which was too heavy went by ship. By firing at the walls and gates with iron balls the citadels fell one by one. Within a week John of Bavaria conquered

1950-547: The rivers Oude and Nieuwe Rijn (Old and New Rhine). The settlement was called Leithon . The name is from Germanic * leitha (canal). Leiden has erroneously been associated with the Roman outpost Lugdunum Batavorum . This was thought to be located at the Burcht of Leiden, and the city's name was thought to be derived from the Latin name Lugdunum. However, the castellum was in fact closer to

2000-459: The siege of 1574, but it quickly recovered to 45,000 in 1622 and may have come near to 70,000 c.  1670 . During the Dutch Golden Era, Leiden was the second largest city of Holland after Amsterdam. It played a crucial role in the establishment of modern chemistry and medicine due to the work by Herman Boerhaave (1668–1738). Leiden slumped from the late 17th century on, mainly due to

2050-511: The space was turned into a public park, the Van der Werff park. In 1842, the railroad from Leiden to Haarlem was inaugurated and one year later the railway to The Hague (Den Haag) was completed, resulting in some social and economic improvement. Perhaps the most important piece of Dutch history contributed by Leiden was the Constitution of the Netherlands . Johan Rudolf Thorbecke (1798–1872) wrote

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2100-503: The strategically important junction of the two arms of the Oude Rijn stands the old castle de Burcht , a circular tower built on an earthen mound. The mound probably was a refuge against high water before a small wooden fortress was built on top of it in the 11th century. The citadel is a so-called motte-and-bailey castle. Of Leiden's old city gates only two are left, the Zijlpoort and

2150-467: The time, the building did justice to nursing practices and operation techniques, but after a few decades it was already obsolete. More laboratory space was needed, and safer and more comfortable conditions for patients and staff alike. The new hospital on Rijnsburgerweg, built in the early 1920s on the basis of the pavilion system, made way in the 1980s and 1990s for the present Building 1 of the LUMC. Medicine has changed and developed beyond recognition over

2200-482: The town of Katwijk , whereas the Roman settlement near Leiden was called Matilo . In 1420, during the Hook and Cod wars , Duke John III of Bavaria along with his army marched from Gouda in the direction of Leiden in order to conquer the city since Leiden did not pay the new Count of Holland Jacqueline, Countess of Hainaut , his niece and only daughter of Count William VI of Holland . Burgrave Filips of Wassenaar and

2250-399: The university are the national institution for East Indian languages, ethnology and geography ; the botanical gardens, founded in 1587; the observatory (1860); the museum of antiquities ( Rijksmuseum van Oudheden ); and the ethnographical museum, of which P.   F. von Siebold's Japanese collection was the nucleus ( Rijksmuseum voor Volkenkunde ). This collection is now housed in

2300-594: The very first teaching hospital in the Caeciliagasthuis in Leiden (now the Boerhaave Museum ) professors gave bedside lectures – for example, Herman Boerhaave , in the 18th century. Several times, patients and professors moved to larger and better furnished premises and in 1873 the first university hospital to be built as such opened its doors on Steenstraat (it now houses the National Museum for Ethnology). At

2350-507: Was built and since 1966 it has been the municipal boundary between Leiden and Zoeterwoude. A datacenter from SWIFT is located in Zoeterwoude. The main brewery of Heineken International is located in Zoeterwoude. Leiden Leiden ( / ˈ l aɪ d ən / LY -dən , Dutch pronunciation: [ˈlɛidə(n)] ; in English and archaic Dutch also Leyden )

2400-454: Was built. In 1574, Zoeterwoude was burnt to the ground and its polders inundated by Leideners in order to increase the range of the city's cannons. Almost no inhabitants remained in Zoeterwoude. Around 1650, Zoeterwoude had been almost rebuilt and 50 years later it was prospering. After 1800, Leiden started a long series of annexations, reducing the land area of Zoeterwoude. In 1960, the A4 motorway

2450-488: Was hit hard by Allied bombardments. The areas surrounding the railway station and Marewijk were almost completely destroyed. The University of Leiden is famous for its many discoveries including Snell's law (by Willebrord Snellius ) and the famous Leyden jar , a capacitor made from a glass jar, invented in Leiden by Pieter van Musschenbroek in 1746. Another development was in cryogenics : Heike Kamerlingh Onnes (1913 Nobel prize winner in physics ) liquefied helium for

2500-595: Was originally part of the Katharina Hospital. In 1584 it became the church of Protestant refugees from the Southern Netherlands (Brugge) and France. Later churches in the centre include the St. Joseph in expressionistic style. The city centre contains many buildings that are in use by the University of Leiden . The Academy Building is housed in a former 16th-century convent . Among the institutions connected with

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