181-656: Howard Phillips Lovecraft ( US : / ˈ l ʌ v k r æ f t / , UK : / ˈ l ʌ v k r ɑː f t / ; August 20, 1890 – March 15, 1937) was an American writer of weird , science , fantasy , and horror fiction . He is best known for his creation of the Cthulhu Mythos . Born in Providence, Rhode Island , Lovecraft spent most of his life in New England . After his father's institutionalization in 1893, he lived affluently until his family's wealth dissipated after
362-698: A cot–caught merger , which is rapidly spreading throughout the whole country. However, the South, Inland North, and a Northeastern coastal corridor passing through Rhode Island, New York City, Philadelphia, and Baltimore typically preserve an older cot–caught distinction. For that Northeastern corridor, the realization of the THOUGHT vowel is particularly marked , as depicted in humorous spellings, like in tawk and cawfee ( talk and coffee ), which intend to represent it being tense and diphthongal : [oə] . A split of TRAP into two separate phonemes , using different
543-410: A Weird Tales story that hinted at necrophilia , although after Lovecraft's death, Wright accepted many of the stories he had originally rejected. Sonia also became ill and immediately after recovering, relocated to Cincinnati , and then to Cleveland; her employment required constant travel. Added to his feelings of failure in a city with a large immigrant population, Lovecraft's single-room apartment
724-405: A fast heart rate . It is caused by cytokines released by the immune system in response to lipoproteins released from rupturing syphilis bacteria. Penicillin is an effective treatment for syphilis in pregnancy but there is no agreement on which dose or route of delivery is most effective. In 2012, about 0.5% of adults were infected with syphilis, with 6 million new cases. In 1999, it
905-520: A pronunciations for example in gap [æ] versus gas [eə] , further defines New York City as well as Philadelphia–Baltimore accents. Most Americans preserve all historical /r/ sounds, using what is known as a rhotic accent . The only traditional r -dropping (or non-rhoticity) in regional U.S. accents variably appears today in eastern New England , New York City , and some of the former plantation South primarily among older speakers (and, relatedly, some African-American Vernacular English across
1086-760: A suffumigation . It was also treated by ingestion of mercury compounds. Once the disease had gained a strong foothold, however, the amounts and forms of mercury necessary to control its development exceeded the human body's ability to tolerate it, and the treatment became worse and more lethal than the disease. Nevertheless, medically directed mercury poisoning became widespread through the 17th, 18th, and 19th centuries in Europe, North America, and India. Mercury salts such as mercury (II) chloride were still in prominent medical use as late as 1916, and considered effective and worthwhile treatments. The first-line treatment for uncomplicated syphilis (primary or secondary stages) remains
1267-503: A "nervous collapse" and "a sort of breakdown", in one letter blaming it on the stress of high school despite his enjoying it. In another letter concerning the events of 1908, he notes, "I was and am prey to intense headaches, insomnia, and general nervous weakness which prevents my continuous application to any thing". Although Lovecraft maintained that he was going to attend Brown University after high school, he never graduated and never attended school again. Whether Lovecraft suffered from
1448-489: A French invasion ( Italian War of 1494–98 ). Since it was claimed to have been spread by French troops, it was initially called the "French disease" by the people of Naples. The disease reached London in 1497 and was recorded at St Bartholomew's Hospital as infecting 10 out of the 20 patients. In 1530, the pastoral name "syphilis" (the name of a character) was first used by the Italian physician and poet Girolamo Fracastoro as
1629-516: A calm indifference to the reception of his works, Lovecraft was in reality extremely sensitive to criticism and easily precipitated into withdrawal. He was known to give up trying to sell a story after it was rejected once. Sometimes, as with The Shadow over Innsmouth , he wrote a story that might have been commercially viable but did not try to sell it. Lovecraft even ignored interested publishers. He failed to reply when one inquired about any novel Lovecraft might have ready: although he had completed such
1810-484: A child. Brobst further ventured that Lovecraft's 1908 breakdown was attributed to a "hysteroid seizure", a term that has become synonymous with atypical depression . In another letter concerning the events of 1908, Lovecraft stated that he "could hardly bear to see or speak to anyone, & liked to shut out the world by pulling down dark shades & using artificial light". Few of Lovecraft and Susie's activities between late 1908 and 1913 were recorded. Lovecraft described
1991-616: A complex phenomenon of "both convergence and divergence": some accents are homogenizing and leveling , while others are diversifying and deviating further away from one another. Having been settled longer than the American West Coast, the East Coast has had more time to develop unique accents, and it currently comprises three or four linguistically significant regions, each of which possesses English varieties both different from each other as well as quite internally diverse: New England ,
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#17328445728262172-447: A consonant, such as in pearl , car and fort . Non-rhotic American accents, those that do not pronounce ⟨r⟩ except before a vowel, such as some accents of Eastern New England , New York City , and African-Americans , and a specific few (often older ones) spoken by Southerners , are often quickly noticed by General American listeners and perceived as sounding especially ethnic, regional, or antiquated. Rhoticity
2353-662: A desire that his life might end. Lovecraft's later response was relief, as he became able to live independently from his mother. His physical health also began to improve, although he was unaware of the exact cause. Despite Lovecraft's reaction, he continued to attend amateur journalist conventions. Lovecraft met his future wife, Sonia Greene , at one such convention in July. Lovecraft's aunts disapproved of his relationship with Sonia. Lovecraft and Greene married on March 3, 1924, and relocated to her Brooklyn apartment at 259 Parkside Avenue; she thought he needed to leave Providence to flourish and
2534-775: A diary of his illness until he was physically incapable of holding a pen. After a small funeral, Lovecraft was buried in Swan Point Cemetery and was listed alongside his parents on the Phillips family monument. In 1977, fans erected a headstone in the same cemetery, on which they inscribed his name, the dates of his birth and death, and the phrase "I AM PROVIDENCE"—a line from one of his personal letters. Defunct Newspapers Journals TV channels Websites Other Economics Gun rights Identity politics Nativist American English American English , sometimes called United States English or U.S. English ,
2715-438: A diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet. There may also be sores in the mouth or vagina. Latent syphilis has no symptoms and can last years. In tertiary syphilis, there are gummas (soft, non-cancerous growths), neurological problems, or heart symptoms. Syphilis has been known as " the great imitator " because it may cause symptoms similar to many other diseases. Syphilis
2896-427: A downturn, which resulted in the slow erosion of his family's wealth. He was forced to let his family's hired servants go, leaving Lovecraft, Whipple, and Susie, being the only unmarried sister, alone in the family home. In the spring of 1904, Whipple's largest business venture suffered a catastrophic failure. Within months, he died at age 70 due to a stroke . After Whipple's death, Susie was unable to financially support
3077-400: A form of chemotherapy , elemental mercury had been used to treat skin diseases in Europe as early as 1363. As syphilis spread, preparations of mercury were among the first medicines used to combat it. Mercury is in fact highly anti-microbial: by the 16th century it was sometimes found to be sufficient to halt development of the disease when applied to ulcers as an inunction or when inhaled as
3258-595: A guiding influence on his worldview. He began publishing the periodical Rhode Island Journal of Astronomy , using the hectograph printing method. Lovecraft went in and out of elementary school repeatedly, oftentimes with home tutors making up for the lost years, missing time due to health concerns that have not been determined. In their written recollections, his peers described him as withdrawn but welcoming to those who shared his then-current fascination with astronomy, inviting them to look through his prized telescope. By 1900, Whipple's various business concerns were suffering
3439-499: A letter to Weird Tales praising a then-recent reprint of Lovecraft's " The Rats in the Walls " and discussing some of the Gaelic references used within. Its editor, Farnsworth Wright, forwarded the letter to Lovecraft, who responded positively to Howard, and soon the two writers were engaged in a vigorous correspondence that lasted for the rest of Howard's life. Howard quickly became a member of
3620-586: A merger with the THOUGHT ( caught ) set. Having taken place prior to the unrounding of the cot vowel, it results in lengthening and perhaps raising, merging the more recently separated vowel into the THOUGHT vowel in the following environments: before many instances of /f/ , /θ/ , and particularly /s/ (as in Austria, cloth, cost, loss, off, often, etc.), a few instances before /ŋ/ (as in strong, long, wrong ), and variably by region or speaker in gone , on , and certain other words. Unlike American accents,
3801-504: A mortal sin in medieval times. It remains mysterious why the authors of medieval medical treatises so uniformly refrained from describing syphilis or commenting on its existence in the population. Many may have confused it with other diseases such as leprosy ( Hansen's disease ) or elephantiasis . The great variety of symptoms of treponematosis, the different ages at which the various diseases appear, and its widely divergent outcomes depending on climate and culture, would have added greatly to
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#17328445728263982-399: A mortality rate of 8% to 58%, with a greater death rate among males. The symptoms of syphilis have become less severe over the 19th and 20th centuries, in part due to widespread availability of effective treatment, and partly due to virulence of the bacteria. With early treatment, few complications result. Syphilis increases the risk of HIV transmission by two to five times, and coinfection
4163-425: A myth?" At the age of eight, he took a keen interest in the sciences, particularly astronomy and chemistry. He also examined the anatomical books that were held in the family library, which taught him the specifics of human reproduction that were not yet explained to him. As a result, he found that it "virtually killed my interest in the subject". In 1902, according to Lovecraft's later correspondence, astronomy became
4344-636: A nice day , for sure); many are now distinctly old-fashioned (swell, groovy). Some English words now in general use, such as hijacking, disc jockey , boost, bulldoze and jazz , originated as American slang. American English has always shown a marked tendency to use words in different parts of speech and nouns are often used as verbs . Examples of nouns that are now also verbs are interview, advocate, vacuum, lobby, pressure, rear-end, transition, feature, profile, hashtag, head, divorce, loan, estimate, X-ray, spearhead, skyrocket, showcase, bad-mouth, vacation , major, and many others. Compounds coined in
4525-566: A physical ailment, a mental one, or some combination thereof has never been determined. An account from a high school classmate described Lovecraft as exhibiting "terrible tics" and that at times "he'd be sitting in his seat and he'd suddenly up and jump". Harry K. Brobst, a psychology professor, examined the account and claimed that chorea minor was the probable cause of Lovecraft's childhood symptoms, while noting that instances of chorea minor after adolescence are very rare. In his letters, Lovecraft acknowledged that he suffered from bouts of chorea as
4706-475: A process of extensive dialect mixture and leveling in which English varieties across the colonies became more homogeneous compared with the varieties in Britain. English thus predominated in the colonies even by the end of the 17th century's first immigration of non-English speakers from Western Europe and Africa. Additionally, firsthand descriptions of a fairly uniform American English (particularly in contrast to
4887-657: A series of other vowel shifts in the same region, known by linguists as the " Inland North ". The Inland North shares with the Eastern New England dialect (including Boston accents ) a backer tongue positioning of the GOOSE /u/ vowel (to [u] ) and the MOUTH /aʊ/ vowel (to [ɑʊ~äʊ] ) in comparison to the rest of the country. Ranging from northern New England across the Great Lakes to Minnesota, another Northern regional marker
5068-449: A single dose of intramuscular benzathine benzylpenicillin . The bacterium is highly vulnerable to penicillin when treated early, and a treated individual is typically rendered non-infective in about 24 hours. Doxycycline and tetracycline are alternative choices for those allergic to penicillin; due to the risk of birth defects , these are not recommended for pregnant women. Resistance to macrolides , rifampicin , and clindamycin
5249-527: A slow doubling time of greater than 30 hours. The bacterium is known for its ability to evade the immune system and its invasiveness. Syphilis is transmitted primarily by sexual contact or during pregnancy from a mother to her baby; the bacterium is able to pass through intact mucous membranes or compromised skin. It is thus transmissible by kissing near a lesion, as well as manual , oral , vaginal , and anal sex . Approximately 30% to 60% of those exposed to primary or secondary syphilis will get
5430-514: A survey, completed in 2003, polling English speakers across the United States about their specific everyday word choices, hoping to identify regionalisms. The study found that most Americans prefer the term sub for a long sandwich, soda (but pop in the Great Lakes region and generic coke in the South) for a sweet and bubbly soft drink , you or you guys for the plural of you (but y'all in
5611-496: A taboo. The magnitude of its morbidity and mortality in those centuries reflected that, unlike today, there was no adequate understanding of its pathogenesis and no truly effective treatments. Its damage was caused not so much by great sickness or death early in the course of the disease but rather by its gruesome effects decades after infection as it progressed to neurosyphilis with tabes dorsalis . Mercury compounds and isolation were commonly used, with treatments often worse than
H. P. Lovecraft - Misplaced Pages Continue
5792-400: A term coined by later authors, encompasses Lovecraft's stories that share a commonality in the revelation of cosmic insignificance, initially realistic settings, and recurring entities and texts. The prose poem " Nyarlathotep " and the short story " The Crawling Chaos ", in collaboration with Winifred Virginia Jackson, were written in late 1920. Following in early 1921 came " The Nameless City ",
5973-419: A third of infected people develop tertiary disease. People with tertiary syphilis are not infectious. Gummatous syphilis or late benign syphilis usually occurs 1 to 46 years after the initial infection, with an average of 15 years. This stage is characterized by the formation of chronic gummas , which are soft, tumor-like balls of inflammation which may vary considerably in size. They typically affect
6154-724: A tiny apartment. He lost approximately 40 pounds (18 kg) of body weight by 1926, when he left for Providence. Back in Providence, Lovecraft lived with his aunts in a "spacious brown Victorian wooden house" at 10 Barnes Street until 1933. He then moved to 66 Prospect Street, which became his final home. The period beginning after his return to Providence contains some of his most prominent works, including The Dream-Quest of Unknown Kadath , The Case of Charles Dexter Ward , "The Call of Cthulhu", and The Shadow over Innsmouth . The former two stories are partially autobiographical, as scholars have argued that The Dream-Quest of Unknown Kadath
6335-453: A variation of American English in these islands. In 2021, about 245 million Americans, aged 5 or above, spoke English at home: a majority of the United States total population of roughly 330 million people. The United States has never had an official language at the federal level, but English is commonly used at the federal level and in states without an official language. 32 of the 50 states, in some cases as part of what has been called
6516-553: A work, The Case of Charles Dexter Ward , it was never typed up. A few years after Lovecraft moved to Providence, he and his wife Sonia Greene, having lived separately for so long, agreed to an amicable divorce. Greene moved to California in 1933 and remarried in 1936, unaware that Lovecraft, despite his assurances to the contrary, never officially signed the final decree. As a result of the Great Depression , he shifted towards socialism , decrying both his prior political beliefs and
6697-411: A writer for 11 years until his death from intestinal cancer at the age of 46. Lovecraft's literary corpus is rooted in cosmicism , which was simultaneously his personal philosophy and the main theme of his fiction. Cosmicism posits that humanity is an insignificant part of the cosmos and could be swept away at any moment. He incorporated fantasy and science fiction elements into his stories, representing
6878-583: Is benzathine benzylpenicillin injected into a muscle . In those who have a severe penicillin allergy , doxycycline or tetracycline may be used. In those with neurosyphilis , intravenous benzylpenicillin or ceftriaxone is recommended. During treatment people may develop fever, headache, and muscle pains , a reaction known as Jarisch–Herxheimer . In 2015, about 45.4 million people had syphilis infections, of which six million were new cases. During 2015, it caused about 107,000 deaths, down from 202,000 in 1990. After decreasing dramatically with
7059-555: Is a notifiable disease in many countries, including Canada, the European Union , and the United States. This means health care providers are required to notify public health authorities, which will then ideally provide partner notification to the person's partners. Physicians may also encourage patients to send their partners to seek care. Several strategies have been found to improve follow-up for STI testing, including email and text messaging of reminders for appointments. As
7240-458: Is about Lovecraft's return to Providence and The Case of Charles Dexter Ward is, in part, about the city itself. The former story also represents a partial repudiation of Dunsany's influence, as Lovecraft decided that his style did not come to him naturally. At this time, he frequently revised work for other authors and did a large amount of ghostwriting, including The Mound , "Winged Death", and "The Diary of Alonzo Typer". Client Harry Houdini
7421-599: Is also associated with miscarriage . The main dental defects seen in congenital syphilis are the peg-shaped, notched incisors known as Hutchinson's teeth and so-called mulberry molars (also known as Moon or Fournier molars), defective permanent molars with rounded, deformed crowns resembling a mulberry . Treponema pallidum subspecies pallidum is a spiral-shaped, Gram-negative , highly mobile bacterium. Two other human diseases are caused by related Treponema pallidum subspecies, yaws (subspecies pertenue ) and bejel (subspecies endemicum ), and one further caused by
H. P. Lovecraft - Misplaced Pages Continue
7602-642: Is also associated with the United States, perhaps mostly in the Midwest and the South. American accents that have not undergone the cot–caught merger (the lexical sets LOT and THOUGHT ) have instead retained a LOT – CLOTH split : a 17th-century distinction in which certain words (labeled as the CLOTH lexical set ) separated away from the LOT set. The split, which has now reversed in most British English, simultaneously shifts this relatively recent CLOTH set into
7783-637: Is also home to a creole language known commonly as Hawaiian Pidgin , and some Hawaii residents speak English with a Pidgin-influenced accent. American English also gave rise to some dialects outside the country, for example, Philippine English , beginning during the American occupation of the Philippines and subsequently the Insular Government of the Philippine Islands ; Thomasites first established
7964-570: Is believed to have infected 12 million additional people, with greater than 90% of cases in the developing world . It affects between 700,000 and 1.6 million pregnancies a year, resulting in spontaneous abortions , stillbirths , and congenital syphilis. During 2015, it caused about 107,000 deaths, down from 202,000 in 1990. In sub-Saharan Africa , syphilis contributes to approximately 20% of perinatal deaths . Rates are proportionally higher among intravenous drug users , those who are infected with HIV , and men who have sex with men. In
8145-518: Is common (30–60% in some urban centers). In 2015, Cuba became the first country to eliminate mother-to-child transmission of syphilis. Paleopathologists have known for decades that syphilis was present in the Americas before European contact. The situation in Europe and Afro-Eurasia has been murkier and caused considerable debate. According to the Columbian theory, syphilis was brought to Spain by
8326-526: Is common in most American accents despite being now rare in England because, during the 17th-century British colonization, nearly all dialects of English were rhotic, and most North American English simply remained that way. The preservation of rhoticity in North America was also supported by continuing waves of rhotic-accented Scotch-Irish immigrants, most intensely during the 18th century (and moderately during
8507-495: Is divided into early latent and late latent stages. Early latent syphilis is defined by the World Health Organization as less than 2 years after original infection. Early latent syphilis is infectious as up to 25% of people can develop a recurrent secondary infection (during which bacteria are actively replicating and are infectious). Two years after the original infection the person will enter late latent syphilis and
8688-589: Is effective at reducing the transmission of syphilis. The CDC states, "The surest way to avoid transmission of sexually transmitted diseases, including syphilis, is to abstain from sexual contact or to be in a long-term mutually monogamous relationship with a partner who has been tested and is known to be uninfected." Congenital syphilis in the newborn can be prevented by screening mothers during early pregnancy and treating those who are infected. The United States Preventive Services Task Force (USPSTF) strongly recommends universal screening of all pregnant women, while
8869-447: Is most commonly spread through sexual activity . It may also be transmitted from mother to baby during pregnancy or at birth, resulting in congenital syphilis . Other diseases caused by Treponema bacteria include yaws ( T. pallidum subspecies pertenue ), pinta ( T. carateum ), and nonvenereal endemic syphilis ( T. pallidum subspecies endemicum ). These three diseases are not typically sexually transmitted. Diagnosis
9050-430: Is not as infectious as the early phase. The latent phase of syphilis can last many years after which, without treatment, approximately 15-40% of people can develop tertiary syphilis. Tertiary syphilis may occur approximately 3 to 15 years after the initial infection and may be divided into three different forms: gummatous syphilis (15%), late neurosyphilis (6.5%), and cardiovascular syphilis (10%). Without treatment,
9231-559: Is not generally possible to contract syphilis through toilet seats, daily activities, hot tubs, or sharing eating utensils or clothing. This is mainly because the bacteria die very quickly outside of the body, making transmission by objects extremely difficult. Syphilis is difficult to diagnose clinically during early infection. Confirmation is either via blood tests or direct visual inspection using dark field microscopy . Blood tests are more commonly used, as they are easier to perform. Diagnostic tests are unable to distinguish between
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#17328445728269412-501: Is not known whether Lovecraft was simply kept ignorant of his father's illness or whether his later statements were intentionally misleading. After his father's institutionalization, Lovecraft resided in the family home with his mother, his maternal aunts Lillian and Annie, and his maternal grandparents Whipple and Robie. According to family friends, Susie doted on the young Lovecraft excessively, pampering him and never letting him out of her sight. Lovecraft later recollected that his mother
9593-420: Is often identified by Americans as a "country" accent, and is defined by the /aɪ/ vowel losing its gliding quality : [aː] , the initiation event for a complicated Southern vowel shift, including a " Southern drawl " that makes short front vowels into distinct-sounding gliding vowels . The fronting of the vowels of GOOSE , GOAT , MOUTH , and STRUT tends to also define Southern accents as well as
9774-399: Is often present. Ceftriaxone , a third-generation cephalosporin antibiotic , may be as effective as penicillin-based treatment. It is recommended that a treated person avoid sex until the sores are healed. In comparison to azithromycin for treatment in early infection, there is lack of strong evidence for superiority of azithromycin to benzathine penicillin G. For neurosyphilis, due to
9955-561: Is the common language at home, in public, and in government. Syphilis Syphilis ( / ˈ s ɪ f ə l ɪ s / ) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum . The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary. The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration usually between 1 cm and 2 cm in diameter) though there may be multiple sores. In secondary syphilis,
10136-635: Is the set of varieties of the English language native to the United States. English is the most widely spoken language in the United States ; the de facto common language used in government, education, and commerce; and an official language in 32 of the 50 U.S. states . Since the late 20th century, American English has become the most influential form of English worldwide. Varieties of American English include many patterns of pronunciation, vocabulary, grammar and particularly spelling that are unified nationwide but distinct from other English dialects around
10317-463: Is the variable fronting of /ɑ/ before /r/ , for example, appearing four times in the stereotypical Boston shibboleth Park the car in Harvard Yard . Several other phenomena serve to distinguish regional U.S. accents. Boston , Pittsburgh , Upper Midwestern , and Western U.S. accents have fully completed a merger of the LOT vowel with the THOUGHT vowel ( /ɑ/ and /ɔ/ , respectively):
10498-416: Is usually made by using blood tests ; the bacteria can also be detected using dark field microscopy . The Centers for Disease Control and Prevention (U.S.) recommends for all pregnant women to be tested. The risk of sexual transmission of syphilis can be reduced by using a latex or polyurethane condom . Syphilis can be effectively treated with antibiotics . The preferred antibiotic for most cases
10679-562: The Anglophilic opinions he maintained throughout his life, he openly criticized other UAPA contributors for their "Americanisms" and "slang". Often, these criticisms were embedded in xenophobic and racist statements that the "national language" was being negatively changed by immigrants. In mid-1915, Lovecraft was elected vice-president of the UAPA. Two years later, he was elected president and appointed other board members who mostly shared his belief in
10860-476: The English-only movement , have adopted legislation granting official or co-official status to English. Typically only "English" is specified, not a particular variety like American English. (From 1923 to 1969, the state of Illinois recognized its official language as "American", meaning American English.) Puerto Rico is the largest example of a United States territory in which another language – Spanish –
11041-404: The Great Depression , Lovecraft's political views became more socialist while still remaining elitist and aristocratic. Throughout his adult life, Lovecraft was never able to support himself from his earnings as an author and editor. He was virtually unknown during his lifetime and was almost exclusively published in pulp magazines before his death. A scholarly revival of Lovecraft's work began in
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#173284457282611222-608: The Mid-Atlantic states (including a New York accent as well as a unique Philadelphia–Baltimore accent ), and the South . As of the 20th century, the middle and eastern Great Lakes area , Chicago being the largest city with these speakers, also ushered in certain unique features, including the fronting of the LOT /ɑ/ vowel in the mouth toward [a] and tensing of the TRAP /æ/ vowel wholesale to [eə] . These sound changes have triggered
11403-544: The Native American languages . Examples of such names are opossum , raccoon , squash , moose (from Algonquian ), wigwam , and moccasin . American English speakers have integrated traditionally non-English terms and expressions into the mainstream cultural lexicon; for instance, en masse , from French ; cookie , from Dutch ; kindergarten from German , and rodeo from Spanish . Landscape features are often loanwords from French or Spanish, and
11584-702: The Scientific Gazette , which dealt mostly with chemistry. It was also during this period that Lovecraft produced the first of the fictional works that he was later known for, namely " The Beast in the Cave " and " The Alchemist ". It was in 1908, prior to what would have been his high school graduation, that Lovecraft suffered another unidentified health crisis, though this instance was more severe than his prior illnesses. The exact circumstances and causes remain unknown. The only direct records are Lovecraft's own correspondence wherein he retrospectively described it variously as
11765-592: The United States Army . Though he passed the physical exam, he told Kleiner that his mother threatened to do anything, legal or otherwise, to prove that he was unfit for service. After his failed attempt to serve in World War I, he attempted to enroll in the Rhode Island Army National Guard , but his mother used her family connections to prevent it. During the winter of 1918–1919, Susie, exhibiting
11946-425: The World Health Organization (WHO) recommends all women be tested at their first antenatal visit and again in the third trimester . If they are positive, it is recommended their partners also be treated. Congenital syphilis is still common in the developing world, as many women do not receive antenatal care at all, and the antenatal care others receive does not include screening. It still occasionally occurs in
12127-596: The cerebrospinal fluid in the setting of a known syphilis infection. Dark field microscopy of serous fluid from a chancre may be used to make an immediate diagnosis. Hospitals do not always have equipment or experienced staff members, and testing must be done within 10 minutes of acquiring the sample. Two other tests can be carried out on a sample from the chancre: direct fluorescent antibody (DFA) and polymerase chain reaction (PCR) tests. DFA uses antibodies tagged with fluorescein , which attach to specific syphilis proteins, while PCR uses techniques to detect
12308-714: The francophile tastes of the 19th century Victorian era Britain (for example they preferred programme for program , manoeuvre for maneuver , cheque for check , etc.). AmE almost always uses -ize in words like realize . BrE prefers -ise , but also uses -ize on occasion (see: Oxford spelling ). There are a few differences in punctuation rules. British English is more tolerant of run-on sentences , called " comma splices " in American English, and American English prefers that periods and commas be placed inside closing quotation marks even in cases in which British rules would place them outside. American English also favors
12489-417: The "delicate passions and emotions proper to negroes and anthropoid apes." This sparked a nearly year-long feud in the magazine's letters section between the two writers and their respective supporters. Lovecraft's most prominent opponent was John Russell, who often replied in verse, and to whom Lovecraft felt compelled to reply because he respected Russell's writing skills. The most immediate effect of this feud
12670-759: The 18th century; apartment , shanty in the 19th century; project, condominium , townhouse , mobile home in the 20th century; and parts thereof ( driveway , breezeway, backyard ) . Industry and material innovations from the 19th century onwards provide distinctive new words, phrases, and idioms through railroading (see further at rail terminology ) and transportation terminology, ranging from types of roads ( dirt roads , freeways ) to infrastructure ( parking lot , overpass , rest area ), to automotive terminology often now standard in English internationally. Already existing English words—such as store , shop , lumber —underwent shifts in meaning; others remained in
12851-595: The 1960s, examples of probable treponematosis —the parent disease of syphilis, bejel , and yaws —in skeletal remains shifted the opinion of some towards a "pre-Columbian" origin. When living conditions changed with urbanization, elite social groups began to practice basic hygiene and started to separate themselves from other social tiers. Consequently, treponematosis was driven out of the age group in which it had become endemic. It then began to appear in adults as syphilis. Because they had never been exposed as children, they were not able to fend off serious illness. Spreading
13032-494: The 1970s, and he is now regarded as one of the most significant 20th-century authors of supernatural horror fiction. Many direct adaptations and spiritual successors followed. Works inspired by Lovecraft, adaptations or original works, began to form the basis of the Cthulhu Mythos, which utilizes Lovecraft's characters, setting, and themes. Lovecraft was born in his family home on August 20, 1890, in Providence, Rhode Island . He
13213-483: The 20th century. The use of English in the United States is a result of British colonization of the Americas . The first wave of English-speaking settlers arrived in North America during the early 17th century, followed by further migrations in the 18th and 19th centuries. During the 17th and 18th centuries, dialects from many different regions of England and the British Isles existed in every American colony, allowing
13394-622: The British form is a back-formation , such as AmE burglarize and BrE burgle (from burglar ). However, while individuals usually use one or the other, both forms will be widely understood and mostly used alongside each other within the two systems. While written American English is largely standardized across the country and spoken American English dialects are highly mutually intelligible, there are still several recognizable regional and ethnic accents and lexical distinctions. The regional sounds of present-day American English are reportedly engaged in
13575-622: The Creation of Niggers", but there is no indication that either were published during his lifetime. In 1911, Lovecraft's letters to editors began appearing in pulp and weird-fiction magazines, most notably Argosy . A 1913 letter critical of Fred Jackson , one of Argosy' s more prominent writers, started Lovecraft down a path that defined the remainder of his career as a writer. In the following letters, Lovecraft described Jackson's stories as being "trivial, effeminate, and, in places, coarse". Continuing, Lovecraft argued that Jackson's characters exhibit
13756-413: The East Coast (perhaps in imitation of 19th-century London speech), even the East Coast has gradually begun to restore rhoticity, due to it becoming nationally prestigious in the 20th century. The pronunciation of ⟨r⟩ is a postalveolar approximant [ ɹ̠ ] or retroflex approximant [ ɻ ] , but a unique "bunched tongue" variant of the approximant r sound
13937-565: The Inland North. Rather than one particular accent, General American is best defined as an umbrella covering an American accent that does not incorporate features associated with some particular region, ethnicity, or socioeconomic group. Typical General American features include rhoticity , the father–bother merger , Mary–marry–merry merger , pre-nasal "short a " tensing , and other particular vowel sounds . General American features are embraced most by Americans who are highly educated or in
14118-473: The Lovecraft Circle, a group of writers and friends all linked through Lovecraft's voluminous correspondence, as he introduced his many like-minded friends to one another and encouraged them to share their stories, utilize each other's fictional creations, and help each other succeed in the field of pulp fiction. Meanwhile, Lovecraft was increasingly producing work that brought him no remuneration. Affecting
14299-560: The South), sneakers for athletic shoes (but often tennis shoes outside the Northeast), and shopping cart for a cart used for carrying supermarket goods. American English and British English (BrE) often differ at the levels of phonology, phonetics, vocabulary, and, to a much lesser extent, grammar and orthography. The first large American dictionary, An American Dictionary of the English Language , known as Webster's Dictionary ,
14480-528: The U.S. Several verbs ending in -ize are of U.S. origin; for example, fetishize, prioritize, burglarize, accessorize, weatherize , etc.; and so are some back-formations (locate, fine-tune, curate, donate, emote, upholster and enthuse). Among syntactic constructions that arose are outside of, headed for, meet up with, back of, etc. Americanisms formed by alteration of some existing words include notably pesky, phony, rambunctious, buddy, sundae , skeeter, sashay and kitty-corner. Adjectives that arose in
14661-563: The U.S. are for instance foothill , landslide (in all senses), backdrop , teenager , brainstorm , bandwagon , hitchhike , smalltime, and a huge number of others. Other compound words have been founded based on industrialization and the wave of the automobile: five-passenger car, four-door sedan, two-door sedan, and station-wagon (called an estate car in British English). Some are euphemistic ( human resources , affirmative action , correctional facility ). Many compound nouns have
14842-662: The U.S. are, for example, lengthy, bossy, cute and cutesy, punk (in all senses), sticky (of the weather), through (as in "finished"), and many colloquial forms such as peppy or wacky . A number of words and meanings that originated in Middle English or Early Modern English and that have been in everyday use in the United States have since disappeared in most varieties of British English; some of these have cognates in Lowland Scots . Terms such as fall ("autumn"), faucet ("tap"), diaper ("nappy"; itself unused in
15023-530: The U.S. while changing in Britain. Science, urbanization, and democracy have been important factors in bringing about changes in the written and spoken language of the United States. From the world of business and finance came new terms ( merger , downsize , bottom line ), from sports and gambling terminology came, specific jargon aside, common everyday American idioms, including many idioms related to baseball . The names of some American inventions remained largely confined to North America ( elevator [except in
15204-427: The U.S.), candy ("sweets"), skillet , eyeglasses , and obligate are often regarded as Americanisms. Fall for example came to denote the season in 16th century England, a contraction of Middle English expressions like "fall of the leaf" and "fall of the year." Gotten ( past participle of get ) is often considered to be largely an Americanism. Other words and meanings were brought back to Britain from
15385-592: The U.S., especially in the second half of the 20th century; these include hire ("to employ"), I guess (famously criticized by H. W. Fowler ), baggage , hit (a place), and the adverbs overly and presently ("currently"). Some of these, for example, monkey wrench and wastebasket , originated in 19th century Britain. The adjectives mad meaning "angry", smart meaning "intelligent", and sick meaning "ill" are also more frequent in American (and Irish) English than British English. Linguist Bert Vaux created
15566-633: The US, Canada, the UK, Australia and Europe, primarily among men who have sex with men. Rates of syphilis among US women have remained stable during this time, while rates among UK women have increased, but at a rate less than that of men. Increased rates among heterosexuals have occurred in China and Russia since the 1990s. This has been attributed to unsafe sexual practices, such as sexual promiscuity, prostitution, and decreasing use of barrier protection. Left untreated, it has
15747-498: The United States about 55,400 people are newly infected each year as of 2014 . African Americans accounted for almost half of all cases in 2010. As of 2014, syphilis infections continue to increase in the United States. In the United States as of 2020, rates of syphilis have increased by more than threefold; in 2018 approximately 86% of all cases of syphilis in the United States were in men. In 2021, preliminary CDC data illustrated that 2,677 cases of congenital syphilis were found in
15928-531: The United States and the United Kingdom suggest that, while spoken American English deviated away from period British English in many ways, it is conservative in a few other ways, preserving certain features 21st-century British English has since lost. Full rhoticity (or "R-fulness") is typical of American accents, pronouncing the phoneme /r/ (corresponding to the letter ⟨r⟩ ) in all environments, including in syllable-final position or before
16109-596: The West and Midwest, and New York Latino English , spoken in the New York metropolitan area . Additionally, ethnic varieties such as Yeshiva English and " Yinglish " are spoken by some American Orthodox Jews , Cajun Vernacular English by some Cajuns in southern Louisiana , and Pennsylvania Dutch English by some Pennsylvania Dutch people. American Indian Englishes have been documented among diverse Indian tribes. The island state of Hawaii , though primarily English-speaking,
16290-561: The absolute number of cases is not large, new ones are continually discovered, most recently in 2015. At least fifteen cases of acquired treponematosis based on evidence from bones, and six examples of congenital treponematosis based on evidence from teeth, are now widely accepted. In several of the twenty-one cases the evidence may also indicate syphilis. In 2020, a group of leading paleopathologists concluded that enough evidence had been collected to prove that treponemal disease, almost certainly including syphilis, had existed in Europe prior to
16471-547: The accents spoken in the " Midland ": a vast band of the country that constitutes an intermediate dialect region between the traditional North and South. Western U.S. accents mostly fall under the General American spectrum. Below, ten major American English accents are defined by their particular combinations of certain vowel sounds: In 2010, William Labov noted that Great Lakes, Philadelphia, Pittsburgh, and West Coast accents have undergone "vigorous new sound changes" since
16652-505: The aeronautical sense ], gasoline ) as did certain automotive terms ( truck , trunk ). New foreign loanwords came with 19th and early 20th century European immigration to the U.S.; notably, from Yiddish ( chutzpah , schmooze, bupkis, glitch ) and German ( hamburger , wiener ). A large number of English colloquialisms from various periods are American in origin; some have lost their American flavor (from OK and cool to nerd and 24/7 ), while others have not ( have
16833-514: The age of seven, and were poems restyling the Odyssey and other Greco-Roman mythological stories. Lovecraft later wrote that during his childhood he was fixated on the Greco-Roman pantheon, and briefly accepted them as genuine expressions of divinity, foregoing his Christian upbringing. He recalled, at five years old, being told Santa Claus did not exist and retorted by asking why "God is not equally
17014-480: The availability of penicillin in the 1940s, rates of infection have increased since the turn of the millennium in many countries, often in combination with human immunodeficiency virus (HIV). This is believed to be partly due to unsafe drug use, increased prostitution , and decreased use of condoms . Syphilis can present in one of four different stages: primary, secondary, latent, and tertiary, and may also occur congenitally . There may be no symptoms . It
17195-555: The bacterium responsible for treponematosis is rare in skeletal remains and fragile, making it notoriously difficult to recover and analyze. Precise dating to the medieval period is not yet possible but work by Kettu Majander et al. uncovering the presence of several different kinds of treponematosis at the beginning of the early modern period argues against its recent introduction from elsewhere. Therefore, they argue, treponematosis—possibly including syphilis—almost certainly existed in medieval Europe. Despite significant progress in tracing
17376-576: The center of a wider group of authors known as the "Lovecraft Circle". They introduced him to Weird Tales , which became his most prominent publisher. Lovecraft's time in New York took a toll on his mental state and financial conditions. He returned to Providence in 1926 and produced some of his most popular works, including The Call of Cthulhu , At the Mountains of Madness , The Shadow over Innsmouth , and The Shadow Out of Time . He remained active as
17557-523: The concepts and themes that his writings later became known for. Lovecraft published another short story, " Beyond the Wall of Sleep " in 1919, which was his first science fiction story. Lovecraft's term as president of the UAPA ended in 1918, and he returned to his former post as chairman of the Department of Public Criticism. In 1917, as Lovecraft related to Kleiner, Lovecraft made an aborted attempt to enlist in
17738-575: The confusion of medical practitioners, as indeed they did right down to the middle of the 20th century. In addition, evidence indicates that some writers on disease feared the political implications of discussing a condition more fatal to elites than to commoners. Historian Jon Arrizabalaga has investigated this question for Castile with startling results revealing an effort to hide its association with elites. The first written records of an outbreak of syphilis in Europe occurred in 1495 in Naples, Italy , during
17919-489: The contrary, Susie maintained this stance. For his part, Lovecraft said he found his mother to be "a positive marvel of consideration". A next-door neighbor later pointed out that what others in the neighborhood often assumed were loud, nocturnal quarrels between mother and son, were actually recitations of William Shakespeare , an activity that seemed to delight them both. During this period, Lovecraft revived his earlier scientific periodicals. He endeavored to commit himself to
18100-406: The country), though the vowel-consonant cluster found in "bird", "work", "hurt", "learn", etc. usually retains its r pronunciation, even in these non-rhotic American accents. Non-rhoticity among such speakers is presumed to have arisen from their upper classes' close historical contact with England, imitating London's r -dropping, a feature that has continued to gain prestige throughout England from
18281-576: The death of his grandfather. Lovecraft then lived with his mother, in reduced financial security, until her institutionalization in 1919. He began to write essays for the United Amateur Press Association and in 1913 wrote a critical letter to a pulp magazine that ultimately led to his involvement in pulp fiction. He became active in the speculative fiction community and was published in several pulp magazines. Lovecraft moved to New York City , marrying Sonia Greene in 1924, and later became
18462-607: The developed world, as those most likely to acquire syphilis are least likely to receive care during pregnancy. Several measures to increase access to testing appear effective at reducing rates of congenital syphilis in low- to middle-income countries. Point-of-care testing to detect syphilis appeared to be reliable, although more research is needed to assess its effectiveness and into improving outcomes in mothers and babies. The CDC recommends that sexually active men who have sex with men be tested at least yearly. The USPSTF also recommends screening among those at high risk. Syphilis
18643-499: The disease and has a limited effect on damage which has already occurred. Serologic cure can be measured when the non-treponemal titers decline by a factor of 4 or more in 6–12 months in early syphilis or 12–24 months in late syphilis. One of the potential side effects of treatment is the Jarisch–Herxheimer reaction . It frequently starts within one hour and lasts for 24 hours, with symptoms of fever, muscle pains, headache, and
18824-399: The disease via sexual contact also led to victims being infected with a massive bacterial load from open sores on the genitalia. Adults in higher socioeconomic groups then became very sick with painful and debilitating symptoms lasting for decades. Often, they died of the disease, as did their children who were infected with congenital syphilis. The difference between rural and urban populations
19005-463: The disease. The causative organism, Treponema pallidum , was first identified by Fritz Schaudinn and Erich Hoffmann , in 1905. The first effective treatment for syphilis was arsphenamine , discovered by Sahachiro Hata in 1909, during a survey of hundreds of newly synthesized organic arsenical compounds led by Paul Ehrlich . It was manufactured and marketed from 1910 under the trade name Salvarsan by Hoechst AG . This organoarsenic compound
19186-505: The disease. Its infectivity is exemplified by the fact that an individual inoculated with only 57 organisms has a 50% chance of being infected. Most new cases in the United States (60%) occur in men who have sex with men; and in this population 20% of syphilis cases were due to oral sex alone. Syphilis can be transmitted by blood products , but the risk is low due to screening of donated blood in many countries. The risk of transmission from sharing needles appears to be limited. It
19367-614: The diverse regional dialects of British English) became common after the mid-18th century, while at the same time speakers' identification with this new variety increased. Since the 18th century, American English has developed into some new varieties, including regional dialects that retain minor influences from waves of immigrant speakers of diverse languages, primarily European languages. Some racial and regional variation in American English reflects these groups' geographic settlement, their de jure or de facto segregation, and patterns in their resettlement. This can be seen, for example, in
19548-742: The double quotation mark ("like this") over the single ('as here'). Vocabulary differences vary by region. For example, autumn is used more commonly in the United Kingdom, whereas fall is more common in American English. Some other differences include: aerial (United Kingdom) vs. antenna, biscuit (United Kingdom) vs. cookie/cracker, car park (United Kingdom) vs. parking lot, caravan (United Kingdom) vs. trailer, city centre (United Kingdom) vs. downtown, flat (United Kingdom) vs. apartment, fringe (United Kingdom) vs. bangs, and holiday (United Kingdom) vs. vacation. AmE sometimes favors words that are morphologically more complex, whereas BrE uses clipped forms, such as AmE transportation and BrE transport or where
19729-485: The fearsome and sordid status of sexually transmitted infections in those centuries. According to a 2020 study, more than 20% of individuals in the age range 15–34 years in late 18th-century London were treated for syphilis. At the time the causative agent was unknown but it was well known that it was spread sexually and also often from mother to child. Its association with sex, especially sexual promiscuity and prostitution , made it an object of fear and revulsion and
19910-462: The first story that falls definitively within the Cthulhu Mythos. In it is one of Lovecraft's most enduring phrases, a couplet recited by Abdul Alhazred; "That is not dead which can eternal lie; And with strange aeons even death may die." In the same year, he also wrote " The Outsider ", which has become one of Lovecraft's most heavily analyzed, and differently interpreted, stories. It has been variously interpreted as being autobiographical, an allegory of
20091-436: The first time I could imagine that my clumsy gropings after art were a little more than faint cries lost in the unlistening void. —Lovecraft in 1921. Lovecraft immersed himself in the world of amateur journalism for most of the following decade. During this period, he advocated for amateurism's superiority to commercialism. Lovecraft defined commercialism as writing for what he considered low-brow publications for pay. This
20272-510: The following two centuries) when this ethnic group eventually made up one-seventh of the colonial population. Scotch-Irish settlers spread from Delaware and Pennsylvania throughout the larger Mid-Atlantic region, the inland regions of both the South and North, and throughout the West: American dialect areas that were all uninfluenced by upper-class non-rhoticity and that consequently have remained consistently rhotic. While non-rhoticity spread on
20453-456: The genitals (2–7%). The most common location in women is the cervix (44%), the penis in heterosexual men (99%), and anally and rectally in men who have sex with men (34%). Lymph node enlargement frequently (80%) occurs around the area of infection, occurring seven to 10 days after chancre formation. The lesion may persist for three to six weeks if left untreated. Secondary syphilis occurs approximately four to ten weeks after
20634-939: The hospital , BrE to hospital ; contrast, however, AmE actress Elizabeth Taylor , BrE the actress Elizabeth Taylor ). Often, these differences are a matter of relative preferences rather than absolute rules; and most are not stable since the two varieties are constantly influencing each other, and American English is not a standardized set of dialects. Differences in orthography are also minor. The main differences are that American English usually uses spellings such as flavor for British flavour , fiber for fibre , defense for defence , analyze for analyse , license for licence , catalog for catalogue and traveling for travelling . Noah Webster popularized such spellings in America, but he did not invent most of them. Rather, "he chose already existing options on such grounds as simplicity, analogy or etymology." Other differences are due to
20815-537: The infection. It may occur early, being either asymptomatic or in the form of syphilitic meningitis ; or late as meningovascular syphilis, manifesting as general paresis or tabes dorsalis . Meningovascular syphilis involves inflammation of the small and medium arteries of the central nervous system. It can present between 1–10 years after the initial infection. Meningovascular syphilis is characterized by stroke, cranial nerve palsies and spinal cord inflammation . Late symptomatic neurosyphilis can develop decades after
20996-656: The influence of 18th-century Protestant Ulster Scots immigrants (known in the U.S. as the Scotch-Irish ) in Appalachia developing Appalachian English and the 20th-century Great Migration bringing African-American Vernacular English to the Great Lakes urban centers. Any phonologically unmarked North American accent falls under an umbrella known as General American. This section mostly refers to such General American features. Studies on historical usage of English in both
21177-475: The large grounds with her. Late 1919 saw Lovecraft become more outgoing. After a period of isolation, he began joining friends in trips to writer gatherings; the first being a talk in Boston presented by Lord Dunsany , whom Lovecraft had recently discovered and idolized. In early 1920, at an amateur writer convention, he met Frank Belknap Long , who ended up being Lovecraft's most influential and closest confidant for
21358-438: The late 18th century onwards, but which has conversely lost prestige in the U.S. since at least the early 20th century. Non-rhoticity makes a word like car sound like cah or source like sauce . New York City and Southern accents are the most prominent regional accents of the country, as well as the most stigmatized and socially disfavored. Southern speech, strongest in southern Appalachia and certain areas of Texas,
21539-584: The lawyer and anarchist writer James Ferdinand Morton Jr. , and the poet Reinhardt Kleiner. On January 1, 1925, Sonia moved from Parkside to Cleveland in response to a job opportunity, and Lovecraft left for a small first-floor apartment on 169 Clinton Street "at the edge of Red Hook "—a location which came to discomfort him greatly. Later that year, the Kalem Club's four regular attendees were joined by Lovecraft along with his protégé Frank Belknap Long , bookseller George Willard Kirk, and Samuel Loveman . Loveman
21720-408: The men who sailed with Christopher Columbus in 1492 and spread from there, with a serious epidemic in Naples beginning as early as 1495. Contemporaries believed the disease sprang from American roots, and in the 16th century physicians wrote extensively about the new disease inflicted on them by the returning explorers. Most evidence supports the Columbian origin hypothesis. However, beginning in
21901-427: The mid-nineteenth century onwards, so they "are now more different from each other than they were 50 or 100 years ago", while other accents, like of New York City and Boston, have remained stable in that same time-frame. However, a General American sound system also has some debated degree of influence nationwide, for example, gradually beginning to oust the regional accent in urban areas of the South and at least some in
22082-617: The most formal contexts, and regional accents with the most General American native features include North Midland, Western New England, and Western accents. Although no longer region-specific, African-American Vernacular English , which remains the native variety of most working- and middle-class African Americans , has a close relationship to Southern dialects and has greatly influenced everyday speech of many Americans, including hip hop culture . Hispanic and Latino Americans have also developed native-speaker varieties of English. The best-studied Latino Englishes are Chicano English , spoken in
22263-464: The most typical deformities, for example, is a collapsed nasal bridge called saddle nose . Salmon discovered that it appeared often in medieval illuminations , especially among the men tormenting Christ in scenes of the crucifixion. The association of saddle nose with men perceived to be so evil they would kill the son of God indicates the artists were thinking of syphilis, which is typically transmitted through sexual intercourse with promiscuous partners,
22444-499: The optic nerve , uveitis , and interstitial keratitis . The acute symptoms usually resolve after three to six weeks; about 25% of people may present with a recurrence of secondary symptoms. Many people who present with secondary syphilis (40–85% of women, 20–65% of men) do not report previously having had the classical chancre of primary syphilis. Latent syphilis is defined as having serologic proof of infection without symptoms of disease. It develops after secondary syphilis and
22625-488: The original infection and includes 2 types; general paresis and tabes dorsalis. General paresis presents with dementia, personality changes, delusions, seizures, psychosis and depression. Tabes dorsalis is characterized by gait instability, sharp pains in the trunk and limbs, impaired positional sensation of the limbs as well as having a positive Romberg's sign . Both tabes dorsalis and general paresis may present with Argyll Robertson pupil which are pupils that constrict when
22806-402: The past forms of a few verbs (for example, AmE/BrE: learned / learnt , burned / burnt , snuck/sneaked , dove/dived ) although the purportedly "British" forms can occasionally be seen in American English writing as well; different prepositions and adverbs in certain contexts (for example, AmE in school, BrE at school ); and whether or not a definite article is used, in very few cases (AmE to
22987-451: The perceived fragility of anthropocentrism . This was tied to his ambivalent views on knowledge. His works were largely set in a fictionalized version of New England. Civilizational decline also plays a major role in his works, as he believed that the West was in decline during his lifetime. Lovecraft's early political views were conservative and traditionalist; additionally, he held a number of racist views for much of his adult life. Following
23168-673: The person focuses on near objects ( accommodation reflex ) but do not constrict when exposed to bright light ( pupillary reflex ). Congenital syphilis is that which is transmitted during pregnancy or during birth. Two-thirds of syphilitic infants are born without symptoms. Common symptoms that develop over the first couple of years of life include enlargement of the liver and spleen (70%), rash (70%), fever (40%), neurosyphilis (20%), and lung inflammation (20%). If untreated, late congenital syphilis may occur in 40%, including saddle nose deformation, Higouménakis' sign , saber shin , or Clutton's joints among others. Infection during pregnancy
23349-456: The poor penetration of benzathine penicillin into the central nervous system , those affected are given large doses of intravenous penicillin G for a minimum of 10 days. If a person is allergic to penicillin, ceftriaxone may be used or penicillin desensitization attempted. Other late presentations may be treated with once-weekly intramuscular benzathine penicillin for three weeks. Treatment at this stage solely limits further progression of
23530-404: The population of 332 million in the United States. Syphilis was very common in Europe during the 18th and 19th centuries. Flaubert found it universal among 19th-century Egyptian prostitutes. In the developed world during the early 20th century, infections declined rapidly with the widespread use of antibiotics , until the 1980s and 1990s. Since 2000, rates of syphilis have been increasing in
23711-499: The possibility of false positives with nontreponemal tests, confirmation is required with a treponemal test, such as Treponema pallidum particle agglutination assay (TPHA) or fluorescent treponemal antibody absorption test (FTA-Abs). Treponemal antibody tests usually become positive two to five weeks after the initial infection and remain positive for many years. Neurosyphilis is diagnosed by finding high numbers of leukocytes (predominately lymphocytes ) and high protein levels in
23892-417: The presence of specific syphilis genes . These tests are not as time-sensitive, as they do not require living bacteria to make the diagnosis. As of 2018 , there is no vaccine effective for prevention. Several vaccines based on treponemal proteins reduce lesion development in an animal model but research continues. Condom use reduces the likelihood of transmission during sex, but does not eliminate
24073-415: The presence of syphilis in past historic periods, definitive findings from paleopathology and aDNA studies are still lacking for the medieval period. Evidence from art is therefore helpful in settling the issue. Research by Marylynn Salmon has demonstrated that deformities in medieval subjects can be identified by comparing them to those of modern victims of syphilis in medical drawings and photographs. One of
24254-747: The primary infection. While secondary disease is known for the many different ways it can manifest, symptoms most commonly involve the skin , mucous membranes , and lymph nodes . There may be a symmetrical, reddish-pink, non-itchy rash on the trunk and extremities, including the palms and soles. The rash may become maculopapular or pustular . It may form flat, broad, whitish, wart-like lesions on mucous membranes, known as condyloma latum . All of these lesions harbor bacteria and are infectious. Other symptoms may include fever , sore throat , malaise , weight loss , hair loss , and headache . Rare manifestations include liver inflammation , kidney disease, joint inflammation , periostitis , inflammation of
24435-487: The psyche, a parody of the afterlife, a commentary on humanity's place in the universe, and a critique of progress. On May 24, 1921, Susie died in Butler Hospital, due to complications from an operation on her gallbladder five days earlier. Lovecraft's initial reaction, expressed in a letter written nine days after Susie's death, was a deep state of sadness that crippled him physically and emotionally. He again expressed
24616-527: The publisher went out of business seven years later. By this point, Lovecraft's literary career was reaching its end. Shortly after having written his last original short story, " The Haunter of the Dark ", he stated that the hostile reception of At the Mountains of Madness had done "more than anything to end my effective fictional career". His declining psychological and physical states made it impossible for him to continue writing fiction. On June 11, Robert E. Howard
24797-445: The remainder of his life. The influence of Dunsany is apparent in his 1919 output, which is part of what was later called Lovecraft's Dream Cycle , including " The White Ship " and " The Doom That Came to Sarnath ". In early 1920, he wrote " The Cats of Ulthar " and " Celephaïs ", which were also strongly influenced by Dunsany. It was later in 1920 that Lovecraft began publishing the earliest Cthulhu Mythos stories. The Cthulhu Mythos,
24978-533: The rising tide of fascism . He thought that socialism was a workable middle ground between what he saw as the destructive impulses of both the capitalists and the Marxists of his day. This was based in a general opposition to cultural upheaval, as well as support for an ordered society. Electorally, he supported Franklin D. Roosevelt , but he thought that the New Deal was not sufficiently leftist. Lovecraft's support for it
25159-453: The risk. The Centers for Disease Control and Prevention (CDC) states, "Correct and consistent use of latex condoms can reduce the risk of syphilis only when the infected area or site of potential exposure is protected. However, a syphilis sore outside of the area covered by a latex condom can still allow transmission, so caution should be exercised even when using a condom." Abstinence from intimate physical contact with an infected person
25340-452: The same account, Hess described a time when they crossed paths in downtown Providence and Susie was unaware of where she was. In March 1919, she was committed to Butler Hospital, like her husband before her. Lovecraft's immediate reaction to Susie's commitment was visceral, writing to Kleiner that "existence seems of little value", and that he wished "it might terminate". During Susie's time at Butler, Lovecraft periodically visited her and walked
25521-442: The skin, bone, and liver, but can occur anywhere. Cardiovascular syphilis usually occurs 10–30 years after the initial infection. The most common complication is syphilitic aortitis , which may result in aortic aneurysm formation. Neurosyphilis refers to an infection involving the central nervous system . Involvement of the central nervous system in syphilis (either asymptomatic or symptomatic) can occur at any stage of
25702-517: The stages of the disease. Blood tests are divided into nontreponemal and treponemal tests. Nontreponemal tests are used initially and include venereal disease research laboratory (VDRL) and rapid plasma reagin (RPR) tests. False positives on the nontreponemal tests can occur with some viral infections, such as varicella (chickenpox) and measles . False positives can also occur with lymphoma , tuberculosis , malaria , endocarditis , connective tissue disease , and pregnancy . Because of
25883-413: The steady continuation of their financial decline highlighted by his uncle's failed business that cost Susie a large portion of their already dwindling wealth. One of Susie's friends, Clara Hess, recalled a visit during which Susie spoke continuously about Lovecraft being "so hideous that he hid from everyone and did not like to walk upon the streets where people could gaze on him." Despite Hess's protests to
26064-589: The study of organic chemistry , Susie buying the expensive glass chemistry assemblage he wanted. Lovecraft found his studies were stymied by the mathematics involved, which he found boring and caused headaches that incapacitated him for the remainder of the day. Lovecraft's first non-self-published poem appeared in a local newspaper in 1912. Called Providence in 2000 A.D. , it envisioned a future where Americans of English descent were displaced by Irish, Italian, Portuguese, and Jewish immigrants. In this period he also wrote racist poetry, including "New-England Fallen" and "On
26245-416: The supremacy of British English over modern American English. Another significant event of this time was the beginning of World War I . Lovecraft published multiple criticisms of the American government and public's reluctance to join the war to protect England, which he viewed as America's ancestral homeland. In 1916, Lovecraft published his first short story, "The Alchemist", in the main UAPA journal, which
26426-522: The symptoms of a nervous breakdown, went to live with her elder sister, Lillian. The nature of Susie's illness is unclear, as her medical papers were later destroyed in a fire at Butler Hospital. Winfield Townley Scott, who was able to read the papers before the fire, described Susie as having suffered a psychological collapse. Neighbour and friend Clara Hess, interviewed in 1948, recalled instances of Susie describing "weird and fantastic creatures that rushed out from behind buildings and from corners at dark." In
26607-485: The time) a single, firm, painless, non-itchy skin ulceration with a clean base and sharp borders approximately 0.3–3.0 cm in size. The lesion may take on almost any form. In the classic form, it evolves from a macule to a papule and finally to an erosion or ulcer . Occasionally, multiple lesions may be present (~40%), with multiple lesions being more common when coinfected with HIV. Lesions may be painful or tender (30%), and they may occur in places other than
26788-488: The title of his Latin poem in dactylic hexameter Syphilis sive morbus gallicus ( Syphilis or The French Disease ) describing the ravages of the disease in Italy. In Great Britain it was also called the "Great Pox". In the 16th through 19th centuries, syphilis was one of the largest public health burdens in prevalence , symptoms, and disability, although records of its true prevalence were generally not kept because of
26969-570: The traditional standard accent of (southern) England, Received Pronunciation (RP), has evolved a trap–bath split . Moreover, American accents preserve /h/ at the start of syllables, while perhaps a majority of the regional dialects of England participate in /h/ dropping , particularly in informal contexts. However, General American is also innovative in a number of its own ways: The process of coining new lexical items started as soon as English-speaking British-American colonists began borrowing names for unfamiliar flora, fauna, and topography from
27150-471: The treponemal diseases is pinta , a skin disease and therefore unrecoverable through paleopathology.) Ancient DNA (aDNA) holds the answer, because just as only aDNA suffices to distinguish between syphilis and other diseases that produce similar symptoms in the body, it alone can differentiate spirochetes that are 99.8 percent identical with absolute accuracy. Progress on uncovering the historical extent of syndromes through aDNA remains slow, however, because
27331-513: The upkeep of the expansive family home on what remained of the Phillips estate. Later that year, she was forced to move to a small duplex with her son. Lovecraft called this time one of the darkest of his life, remarking in a 1934 letter that he saw no point in living anymore; he considered the possibility of committing suicide. His scientific curiosity and desire to know more about the world prevented him from doing so. In fall 1904, he entered high school. Much like his earlier school years, Lovecraft
27512-417: The verb-and-preposition combination: stopover, lineup, tryout, spin-off, shootout , holdup, hideout, comeback, makeover , and many more. Some prepositional and phrasal verbs are in fact of American origin ( win out, hold up, back up/off/down/out, face up to and many others). Noun endings such as -ee (retiree), -ery (bakery), -ster (gangster) and -cian (beautician) are also particularly productive in
27693-406: The very closely related Treponema carateum , pinta . Unlike subspecies pallidum , they do not cause neurological disease. Humans are the only known natural reservoir for subspecies pallidum . It is unable to survive more than a few days without a host . This is due to its small genome (1.14 Mbp ) failing to encode the metabolic pathways necessary to make most of its macronutrients. It has
27874-504: The voyages of Columbus. There is an outstanding issue, however. Damaged teeth and bones may seem to hold proof of pre-Columbian syphilis, but there is a possibility that they point to an endemic form of treponemal disease instead. As syphilis, bejel, and yaws vary considerably in mortality rates and the level of human disease they elicit, it is important to know which one is under discussion in any given case, but it remains difficult for paleopathologists to distinguish among them. (The fourth of
28055-772: The word corn , used in England to refer to wheat (or any cereal), came to denote the maize plant, the most important crop in the U.S. Most Mexican Spanish contributions came after the War of 1812 , with the opening of the West, like ranch (now a common house style ). Due to Mexican culinary influence, many Spanish words are incorporated in general use when talking about certain popular dishes: cilantro (instead of coriander), queso, tacos, quesadillas, enchiladas, tostadas, fajitas, burritos, and guacamole. These words usually lack an English equivalent and are found in popular restaurants. New forms of dwelling created new terms ( lot , waterfront) and types of homes like log cabin , adobe in
28236-609: The world. Any American or Canadian accent perceived as lacking noticeably local, ethnic, or cultural markers is known in linguistics as General American ; it covers a fairly uniform accent continuum native to certain regions of the U.S. but especially associated with broadcast mass media and highly educated speech. However, historical and present linguistic evidence does not support the notion of there being one single mainstream American accent . The sound of American English continues to evolve, with some local accents disappearing, but several larger regional accents having emerged in
28417-550: The young Lovecraft to have an appreciation of literature, especially classical literature and English poetry. In his old age, he helped raise the young H. P. Lovecraft and educated him not only in the classics, but also in original weird tales of "winged horrors" and "deep, low, moaning sounds" which he created for his grandchild's entertainment. The original sources of Phillips's weird tales are unidentified. Lovecraft himself guessed that they originated from Gothic novelists like Ann Radcliffe , Matthew Lewis , and Charles Maturin . It
28598-513: Was "doing and saying strange things at times" for a year before his commitment. The person who reported these symptoms is unknown. Winfield spent five years in Butler before dying in 1898. His death certificate listed the cause of death as general paresis , a term synonymous with late-stage syphilis . Throughout his life, Lovecraft maintained that his father fell into a paralytic state, due to insomnia and overwork, and remained that way until his death. It
28779-416: Was "permanently stricken with grief" after his father's illness. Whipple became a father figure to Lovecraft in this time, Lovecraft later noted that his grandfather became the "centre of my entire universe". Whipple, who often traveled to manage his business, maintained correspondence by letter with the young Lovecraft who, by the age of three, was already proficient at reading and writing. Whipple encouraged
28960-500: Was Jewish, but he and Lovecraft became close friends in spite of the latter's antisemitic attitudes. By the 1930s, writer and publisher Herman Charles Koenig was one of the last to become involved with the Kalem Club. Not long after the marriage, Greene lost her business and her assets disappeared in a bank failure. Lovecraft made efforts to support his wife through regular jobs, but his lack of previous work experience meant he lacked proven marketable skills. The publisher of Weird Tales
29141-434: Was a departure from his usual verse. Due to the encouragement of W. Paul Cook , another UAPA member and future lifelong friend, Lovecraft began writing and publishing more prose fiction. Soon afterwards, he wrote " The Tomb " and " Dagon ". "The Tomb", by Lovecraft's own admission, was greatly influenced by the style and structure of Edgar Allan Poe 's works. Meanwhile, "Dagon" is considered Lovecraft's first work that displays
29322-630: Was also the time when Lovecraft, approximately five-and-a-half years old, started having nightmares that later informed his fictional writings. Specifically, he began to have recurring nightmares of beings he referred to as "night-gaunts". He credited their appearance to the influence of Doré's illustrations, which would "whirl me through space at a sickening rate of speed, the while fretting & impelling me with their detestable tridents ". Thirty years later, night-gaunts appeared in Lovecraft's fiction. Lovecraft's earliest known literary works were written at
29503-473: Was at around this time he wrote the outline for " The Call of Cthulhu ", with its theme of the insignificance of all humanity. During this time, Lovecraft wrote " Supernatural Horror in Literature " on the eponymous subject. It later became one of the most influential essays on supernatural horror. With a weekly allowance Greene sent, Lovecraft moved to a working-class area of Brooklyn Heights , where he resided in
29684-404: Was attempting to make the loss-making magazine profitable and offered the job of editor to Lovecraft, who declined, citing his reluctance to relocate to Chicago on aesthetic grounds. Baird was succeeded by Farnsworth Wright , whose writing Lovecraft criticized. Lovecraft's submissions were often rejected by Wright. This may have been partially due to censorship guidelines imposed in the aftermath of
29865-537: Was based in his view that no other set of reforms were possible at that time. In late 1936, he witnessed the publication of The Shadow over Innsmouth as a paperback book. 400 copies were printed, and the work was advertised in Weird Tales and several fan magazines. However, Lovecraft was displeased, as this book was riddled with errors that required extensive editing. It sold slowly and only approximately 200 copies were bound. The remaining 200 copies were destroyed after
30046-448: Was burgled, leaving him with only the clothes he was wearing. In August 1925, he wrote " The Horror at Red Hook " and " He ". In the latter, the narrator says "My coming to New York had been a mistake; for whereas I had looked for poignant wonder and inspiration [...] I had found instead only a sense of horror and oppression which threatened to master, paralyze, and annihilate me." This was an expression of his despair at being in New York. It
30227-475: Was confirmed in trials in 1943, at which time it became the main treatment. Many famous historical figures, including Franz Schubert , Arthur Schopenhauer , Édouard Manet , Charles Baudelaire , and Guy de Maupassant are believed to have had the disease. Friedrich Nietzsche was long believed to have gone mad as a result of tertiary syphilis , but that diagnosis has recently come into question. The earliest known depiction of an individual with syphilis
30408-452: Was contrasted with his view of "professional publication", which was what he called writing for what he considered respectable journals and publishers. He thought of amateur journalism as serving as practice for a professional career. Lovecraft was appointed chairman of the Department of Public Criticism of the UAPA in late 1914. He used this position to advocate for what he saw as the superiority of archaic English language usage. Emblematic of
30589-506: Was deteriorating. He was suffering from an affliction that he referred to as "grippe". Due to his fear of doctors, Lovecraft was not examined until a month before his death and was diagnosed with terminal cancer of the small intestine . He was hospitalized in the Jane Brown Memorial Hospital and lived in constant pain until his death on March 15, 1937, in Providence. In accordance with his lifelong scientific curiosity, he kept
30770-642: Was during this period that Lovecraft was introduced to some of his earliest literary influences, such as The Rime of the Ancient Mariner illustrated by Gustave Doré , One Thousand and One Nights , Thomas Bulfinch 's Age of Fable , and Ovid 's Metamorphoses . While there is no indication that Lovecraft was particularly close to his grandmother, Robie, her death in 1896 had a profound effect on him. According to him, it sent his family into "a gloom from which it never fully recovered". His mother and aunts wore black mourning dresses that "terrified" him. This
30951-503: Was first noted by Ellis Herndon Hudson, a clinician who published extensively about the prevalence of treponematosis, including syphilis, in times past. The importance of bacterial load was first noted by the physician Ernest Grin in 1952 in his study of syphilis in Bosnia. The most compelling evidence for the validity of the pre-Columbian hypothesis is the presence of syphilitic-like damage to bones and teeth in medieval skeletal remains. While
31132-579: Was informally dubbed the Kalem Club, he acquired a group of encouraging intellectual and literary friends who urged him to submit stories to Weird Tales . Its editor, Edwin Baird , accepted many of Lovecraft's stories for the ailing publication, including " Under the Pyramids ", which was ghostwritten for Harry Houdini . Established informally some years before Lovecraft arrived in New York, the core Kalem Club members were boys' adventure novelist Henry Everett McNeil ,
31313-543: Was informed that his chronically ill mother would not awaken from her coma. He walked out to his car and died by suicide with a pistol that he had stored there. His mother died shortly thereafter. This deeply affected Lovecraft, who consoled Howard's father through correspondence. Almost immediately after hearing about Howard's death, Lovecraft wrote a brief memoir titled "In Memoriam: Robert Ervin Howard", which he distributed to his correspondents. Meanwhile, Lovecraft's physical health
31494-621: Was laudatory, and attempted to help Lovecraft by introducing him to the head of a newspaper syndicate. Plans for a further project, a book titled The Cancer of Superstition , were ended by Houdini's death in 1926. After returning, he also began to engage in antiquarian travels across the eastern seaboard during the summer months. During the spring–summer of 1930, Lovecraft visited, among other locations, New York City, Brattleboro, Vermont , Wilbraham, Massachusetts , Charleston, South Carolina , and Quebec City . Later, in August, Robert E. Howard wrote
31675-501: Was periodically removed from school for long periods for what he termed "near breakdowns". He did say, though, that while having some conflicts with teachers, he enjoyed high school, becoming close with a small circle of friends. Lovecraft also performed well academically, excelling in particular at chemistry and physics. Aside from a pause in 1904, he also resumed publishing the Rhode Island Journal of Astronomy as well as starting
31856-403: Was referred to as "the great imitator" by Sir William Osler due to its varied presentations. Primary syphilis is typically acquired by direct sexual contact with the infectious lesions of another person. Approximately 2–6 weeks after contact (with a range of 10–90 days) a skin lesion, called a chancre , appears at the site and this contains infectious bacteria. This is classically (40% of
32037-449: Was the first modern chemotherapeutic agent . During the 20th century, as both microbiology and pharmacology advanced greatly, syphilis, like many other infectious diseases, became more of a manageable burden than a scary and disfiguring mystery, at least in developed countries among those people who could afford to pay for timely diagnosis and treatment. Penicillin was discovered in 1928, and effectiveness of treatment with penicillin
32218-436: Was the only child of Winfield Scott Lovecraft and Sarah Susan ("Susie"; née Phillips) Lovecraft, who were both of English descent. Susie's family was of substantial means at the time of their marriage, as her father, Whipple Van Buren Phillips, was involved in business ventures. In April 1893, after a psychotic episode in a Chicago hotel, Winfield was committed to Butler Hospital in Providence. His medical records state that he
32399-483: Was the recognition garnered from Edward F. Daas , then head editor of the United Amateur Press Association (UAPA). Daas invited Russell and Lovecraft to join the organization and both accepted, Lovecraft in April 1914. With the advent of United I obtained a renewed will to live; a renewed sense of existence as other than a superfluous weight; and found a sphere in which I could feel that my efforts were not wholly futile. For
32580-423: Was willing to support him financially. Greene, who was married before, later said Lovecraft performed satisfactorily as a lover, but she had to take the initiative in all aspects of the relationship. She attributed Lovecraft's passive nature to a stultifying upbringing by his mother. Lovecraft's weight increased to 200 lb (91 kg) on his wife's home cooking. He was enthralled by New York City , and, in what
32761-469: Was written by Noah Webster in 1828, codifying several of these spellings. Differences in grammar are relatively minor, and do not normally affect mutual intelligibility; these include: typically a lack of differentiation between adjectives and adverbs, employing the equivalent adjectives as adverbs he ran quick / he ran quickly ; different use of some auxiliary verbs ; formal (rather than notional) agreement with collective nouns ; different preferences for
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