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Animal rights is the philosophy according to which many or all sentient animals have moral worth independent of their utility to humans, and that their most basic interests—such as avoiding suffering —should be afforded the same consideration as similar interests of human beings. Broadly speaking, and particularly in popular discourse, the term "animal rights" is often used synonymously with "animal protection" or "animal liberation". More narrowly, "animal rights" refers to the idea that many animals have fundamental rights to be treated with respect as individuals— rights to life , liberty , and freedom from torture that may not be overridden by considerations of aggregate welfare.

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141-462: The Lobster Liberation Front ( LLF ) is an animal rights campaign which first appeared on the coast of Dorset , England in 2004, later spreading to Wales and Scotland . Their methods include releasing lobsters in live storage and sabotaging lobster pots or fishing boats. The LLF consider boiling lobsters alive (the traditional method for cooking them) unacceptable and use direct action to prevent it. Their claim that lobsters, which possess

282-450: A Soviet dog , Laika , became the first of many animals to orbit the Earth . In the 1970s, antibiotic treatments and vaccines for leprosy were developed using armadillos, then given to humans. The ability of humans to change the genetics of animals took an enormous step forward in 1974 when Rudolf Jaenisch could produce the first transgenic mammal , by integrating DNA from simians into

423-590: A 'mild' procedure would be something like a blood test or an MRI scan. The Three Rs (3Rs) are guiding principles for more ethical use of animals in testing. These were first described by W.M.S. Russell and R.L. Burch in 1959. The 3Rs state: The 3Rs have a broader scope than simply encouraging alternatives to animal testing, but aim to improve animal welfare and scientific quality where the use of animals can not be avoided. These 3Rs are now implemented in many testing establishments worldwide and have been adopted by various pieces of legislation and regulations. Despite

564-469: A brain-damaged human could not make moral judgments, moral judgments cannot be used as the distinguishing characteristic for determining who is awarded rights. Cohen writes that the test for moral judgment "is not a test to be administered to humans one by one", but should be applied to the capacity of members of the species in general. Judge Richard Posner of the United States Court of Appeals for

705-489: A broad number of 120 inspectors, the United States Department of Agriculture (USDA) oversees more than 12,000 facilities involved in research, exhibition, breeding, or dealing of animals. Others have criticized the composition of IACUCs, asserting that the committees are predominantly made up of animal researchers and university representatives who may be biased against animal welfare concerns. Larry Carbone,

846-638: A central role in animal advocacy since the 19th century. The anti-vivisection movement in the 19th and early 20th century in England and the United States was largely run by women, including Frances Power Cobbe , Anna Kingsford , Lizzy Lind af Hageby and Caroline Earle White (1833–1916). Garner writes that 70 per cent of the membership of the Victoria Street Society (one of the anti-vivisection groups founded by Cobbe) were women, as were 70 per cent of

987-584: A cure for a disease. Examples of applied research include testing disease treatments, breeding, defense research, and toxicology , including cosmetics testing . In education, animal testing is sometimes a component of biology or psychology courses. Research using animal models has been central to most of the achievements of modern medicine. It has contributed to most of the basic knowledge in fields such as human physiology and biochemistry , and has played significant roles in fields such as neuroscience and infectious disease . The results have included

1128-583: A dozen stolen pets during a raid on a Class B dealer in Arkansas in 2003. Four states in the U.S.— Minnesota , Utah , Oklahoma , and Iowa —require their shelters to provide animals to research facilities. Fourteen states explicitly prohibit the practice, while the remainder either allow it or have no relevant legislation. In the European Union, animal sources are governed by Council Directive 86/609/EEC , which requires lab animals to be specially bred, unless

1269-661: A drug after they had prosecuted a company for selling products that harmed customers. However, in response to the Elixir Sulfanilamide disaster of 1937 in which the eponymous drug killed over 100 users, the US Congress passed laws that required safety testing of drugs on animals before they could be marketed. Other countries enacted similar legislation. In the 1960s, in reaction to the Thalidomide tragedy, further laws were passed requiring safety testing on pregnant animals before

1410-412: A drug can be sold. Although many more invertebrates than vertebrates are used in animal testing, these studies are largely unregulated by law. The most frequently used invertebrate species are Drosophila melanogaster , a fruit fly, and Caenorhabditis elegans , a nematode worm. In the case of C. elegans , the worm's body is completely transparent and the precise lineage of all the organism's cells

1551-502: A fantasy, a world of escape. Scruton singled out Peter Singer , a prominent Australian philosopher and animal-rights activist, for criticism. He wrote that Singer's works, including Animal Liberation , "contain little or no philosophical argument. They derive their radical moral conclusions from a vacuous utilitarianism that counts the pain and pleasure of all living things as equally significant and that ignores just about everything that has been said in our philosophical tradition about

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1692-465: A few main stock centers. For vertebrates, sources include breeders and dealers including Fortrea and Charles River Laboratories , which supply purpose-bred and wild-caught animals; businesses that trade in wild animals such as Nafovanny ; and dealers who supply animals sourced from pounds, auctions, and newspaper ads. Animal shelters also supply the laboratories directly. Large centers also exist to distribute strains of genetically modified animals ;

1833-406: A gradation or spectrum with other types of sentient rights, including human rights and the rights of conscious artificial intelligences (posthuman rights). According to sociologist David Nibert of Wittenberg University , the struggle for animal liberation must happen in tandem with a more generalized struggle against human oppression and exploitation under global capitalism . He says that under

1974-572: A laboratory animal veterinarian, writes that, in his experience, IACUCs take their work very seriously regardless of the species involved, though the use of non-human primates always raises what he calls a "red flag of special concern". A study published in Science magazine in July 2001 confirmed the low reliability of IACUC reviews of animal experiments. Funded by the National Science Foundation,

2115-811: A legitimate sacrifice of interests can vary considerably. Certain forms of animal-rights activism, such as the destruction of fur farms and of animal laboratories by the Animal Liberation Front , have attracted criticism, including from within the animal-rights movement itself, and prompted the U.S. Congress to enact laws, including the Animal Enterprise Terrorism Act , allowing the prosecution of this sort of activity as terrorism . The concept of moral rights for animals dates to Ancient India , with roots in early Jain and Hindu history, while Eastern, African, and Indigenous peoples also have rich traditions of animal protection. In

2256-459: A lower degree of biological similarity with mammals for significant gains in experimental throughput. In the U.S., the numbers of rats and mice used is estimated to be from 11 million to between 20 and 100 million a year. Other rodents commonly used are guinea pigs, hamsters, and gerbils. Mice are the most commonly used vertebrate species because of their size, low cost, ease of handling, and fast reproduction rate. Mice are widely considered to be

2397-510: A means to an end, a view that places him firmly in the abolitionist camp. His theory does not extend to all animals, but only to those that can be regarded as subjects-of-a-life. He argues that all normal mammals of at least one year of age would qualify: ... individuals are subjects-of-a-life if they have beliefs and desires; perception, memory, and a sense of the future, including their own future; an emotional life together with feelings of pleasure and pain; preference- and welfare-interests;

2538-483: A mistake to portray animal rights activists as homogeneous." Even though around 90% of US adults regularly consume meat, almost half of them appear to support a ban on slaughterhouses: in Sentience Institute 's 2017 survey of 1,094 U.S. adults' attitudes toward animal farming, 49% "support a ban on factory farming, 47% support a ban on slaughterhouses, and 33% support a ban on animal farming". The 2017 survey

2679-440: A more egalitarian democratic socialist system, one that would "allow a more just and peaceful order to emerge" and be "characterized by economic democracy and a democratically controlled state and mass media", there would be "much greater potential to inform the public about vital global issues—and the potential for "campaigns to improve the lives of other animals" to be "more abolitionist in nature." Philosopher Steven Best of

2820-415: A negative connotation, implying torture, suffering, and death. The word "vivisection" is preferred by those opposed to this research, whereas scientists typically use the term "animal experimentation". The following text excludes as much as possible practices related to in vivo veterinary surgery , which is left to the discussion of vivisection . The earliest references to animal testing are found in

2961-421: A particular situation". The idea that nonhuman animals are worthy of prima facie rights is to say that, in a sense, animals have rights that can be overridden by many other considerations, especially those conflicting a human's right to life, liberty, property, and the pursuit of happiness. Garry supports his view arguing: ... if a nonhuman animal were to kill a human being in the U.S., it would have broken

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3102-532: A patriarchal society: both are "the used"; the dominated, submissive " Other ". When the British feminist Mary Wollstonecraft (1759–1797) published A Vindication of the Rights of Woman (1792), Thomas Taylor (1758–1835), a Cambridge philosopher, responded with an anonymous parody, A Vindication of the Rights of Brutes (1792), saying that Wollstonecraft's arguments for women's rights could be applied equally to animals,

3243-429: A philosophical context, a prima facie (Latin for "on the face of it" or "at first glance") right is one that appears to be applicable at first glance, but upon closer examination may be outweighed by other considerations. In his book Ethics: A Pluralistic Approach to Moral Theory , Lawrence Hinman characterizes such rights as "the right is real but leaves open the question of whether it is applicable and overriding in

3384-479: A position he intended as reductio ad absurdum . In her works The Sexual Politics of Meat: A Feminist-Vegetarian Critical Theory (1990) and The Pornography of Meat (2004), Carol J. Adams focuses in particular on what she argues are the links between the oppression of women and that of non-human animals. Some transhumanists argue for animal rights, liberation, and "uplift" of animal consciousness into machines. Transhumanism also understands animal rights on

3525-494: A positive view of universal healthcare, favor reducing discrimination against African Americans, the LGBT community and undocumented immigrants, and expanding welfare to aid the poor. Two surveys found that attitudes towards animal rights tactics, such as direct action , are very diverse within the animal rights communities. Near half (50% and 39% in two surveys) of activists do not support direct action. One survey concluded "it would be

3666-614: A practice known as bunching . It was in part out of public concern over the sale of pets to research facilities that the 1966 Laboratory Animal Welfare Act was ushered in—the Senate Committee on Commerce reported in 1966 that stolen pets had been retrieved from Veterans Administration facilities, the Mayo Institute, the University of Pennsylvania, Stanford University, and Harvard and Yale Medical Schools. The USDA recovered at least

3807-609: A prejudice as irrational as any other. They maintain that animals should not be viewed as property or used as food, clothing, entertainment, or beasts of burden merely because they are not human. Multiple cultural traditions around the world such as Jainism , Taoism , Hinduism , Buddhism , Shinto and Animism also espouse forms of animal rights. In parallel to the debate about moral rights, law schools in North America now often teach animal law , and several legal scholars, such as Steven M. Wise and Gary L. Francione , support

3948-555: A reduction from a high of 50 million used in 1970. In 1986, the U.S. Congress Office of Technology Assessment reported that estimates of the animals used in the U.S. range from 10 million to upwards of 100 million each year, and that their own best estimate was at least 17 million to 22 million. In 2016, the Department of Agriculture listed 60,979 dogs, 18,898 cats, 71,188 non-human primates, 183,237 guinea pigs, 102,633 hamsters, 139,391 rabbits, 83,059 farm animals, and 161,467 other mammals,

4089-423: A result, animals are not always receiving basic humane care and treatment and, in some cases, pain and distress are not minimized during and after experimental procedures". According to the report, within a three-year period, nearly half of all American laboratories with regulated species were cited for AWA violations relating to improper IACUC oversight. The USDA OIG made similar findings in a 2005 report. With only

4230-411: A right to life, some control over their environment, company, play, and physical health. Stephen R. L. Clark , Mary Midgley , and Bernard Rollin also discuss animal rights in terms of animals being permitted to lead a life appropriate for their kind. Egalitarianism favors an equal distribution of happiness among all individuals, which makes the interests of the worse off more important than those of

4371-579: A rudimentary nervous system , can feel pain, is the subject of ongoing scientific debate. In March, the village of Worth Matravers , Dorset was targeted when the individuals twice wrecked a fisherman's boat and set lobsters free. The actions were reported to the Southern Animal Rights Coalition, sent anonymously by the LLF. Shortly following this action, £1,000 worth of damage was made in June when it

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4512-618: A total of 820,812, a figure that includes all mammals except purpose-bred mice and rats. The use of dogs and cats in research in the U.S. decreased from 1973 to 2016 from 195,157 to 60,979, and from 66,165 to 18,898, respectively. In the UK, Home Office figures show that 3.79 million procedures were carried out in 2017. 2,960 procedures used non-human primates, down over 50% since 1988. A "procedure" refers here to an experiment that might last minutes, several months, or years. Most animals are used in only one procedure: animals are frequently euthanized after

4653-512: A view summarised by the philosopher Roger Scruton , who writes that only humans have duties, and therefore only humans have rights. Another argument, associated with the utilitarian tradition, maintains that animals may be used as resources so long as there is no unnecessary suffering; animals may have some moral standing, but any interests they have may be overridden in cases of comparatively greater gains to aggregate welfare made possible by their use, though what counts as "necessary" suffering or

4794-429: A worse outcome. There are a number of positions that can be defended from a consequentalist or deontologist perspective, including the capabilities approach , represented by Martha Nussbaum , and the egalitarian approach , which has been examined by Ingmar Persson and Peter Vallentyne . The capabilities approach focuses on what individuals require to fulfill their capabilities: Nussbaum (2006) argues that animals need

4935-497: Is a moral intuition of many, probably most, Americans. We realize that animals feel pain, and we think that to inflict pain without a reason is bad. Nothing of practical value is added by dressing up this intuition in the language of philosophy; much is lost when the intuition is made a stage in a logical argument. When kindness toward animals is levered into a duty of weighting the pains of animals and of people equally, bizarre vistas of social engineering are opened up. Roger Scruton ,

5076-480: Is an accepted version of this page Animal testing , also known as animal experimentation , animal research , and in vivo testing , is the use of non-human animals , such as model organisms , in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in their natural environments or habitats. Experimental research with animals

5217-492: Is exemplified by Peter Singer , and the latter by Tom Regan and Gary Francione . Their differences reflect a distinction philosophers draw between ethical theories that judge the rightness of an act by its consequences (consequentialism/teleological ethics, or utilitarianism), and those that focus on the principle behind the act, almost regardless of consequences (deontological ethics). Deontologists argue that there are acts we should never perform, even if failing to do so entails

5358-456: Is known, while studies in the fly D. melanogaster can use an amazing array of genetic tools. These invertebrates offer some advantages over vertebrates in animal testing, including their short life cycle and the ease with which large numbers may be housed and studied. However, the lack of an adaptive immune system and their simple organs prevent worms from being used in several aspects of medical research such as vaccine development. Similarly,

5499-528: Is less clear, however, legislation in several countries (e.g. U.K., New Zealand , Norway ) protects some invertebrate species if they are being used in animal testing. In the U.S., the defining text on animal welfare regulation in animal testing is the Guide for the Care and Use of Laboratory Animals . This defines the parameters that govern animal testing in the U.S. It states "The ability to experience and respond to pain

5640-457: Is no useful in vitro model system available. The annual use of vertebrate animals—from zebrafish to non-human primates —was estimated at 192 million as of 2015. In the European Union , vertebrate species represent 93% of animals used in research, and 11.5 million animals were used there in 2011. The mouse ( Mus musculus ) is associated with many important biological discoveries of

5781-891: Is regulated to varying degrees in different countries. Animal testing is regulated differently in different countries: in some cases it is strictly controlled while others have more relaxed regulations. There are ongoing debates about the ethics and necessity of animal testing. Proponents argue that it has led to significant advancements in medicine and other fields while opponents raise concerns about cruelty towards animals and question its effectiveness and reliability. There are efforts underway to find alternatives to animal testing such as computer simulation models , organs-on-chips technology that mimics human organs for lab tests, microdosing techniques which involve administering small doses of test compounds to human volunteers instead of non-human animals for safety tests or drug screenings; positron emission tomography (PET) scans which allow scanning of

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5922-418: Is right. "The holders of rights must have the capacity to comprehend rules of duty governing all, including themselves. In applying such rules, [they] ... must recognize possible conflicts between what is in their own interest and what is just. Only in a community of beings capable of self-restricting moral judgments can the concept of a right be correctly invoked." Cohen rejects Singer's argument that, since

6063-435: Is scientifically justified. Researchers are required to consult with the institution's veterinarian and its Institutional Animal Care and Use Committee (IACUC), which every research facility is obliged to maintain. The IACUC must ensure that alternatives, including non-animal alternatives, have been considered, that the experiments are not unnecessarily duplicative, and that pain relief is given unless it would interfere with

6204-594: Is the current research. Zebrafish and humans share similar gastric cancer cells in the gastric cancer xenotransplantation model. This allowed researchers to find that Triphala could inhibit the growth and metastasis of gastric cancer cells. Since zebrafish liver cancer genes are related with humans they have become widely used in liver cancer search, as will as many other cancers. Non-human primates (NHPs) are used in toxicology tests, studies of AIDS and hepatitis, studies of neurology , behavior and cognition, reproduction, genetics , and xenotransplantation . They are caught in

6345-453: Is used with the aim of solving medical problems such as Alzheimer's disease, AIDS, multiple sclerosis, spinal cord injury, many headaches, and other conditions in which there is no useful in vitro model system available. Toxicology testing became important in the 20th century. In the 19th century, laws regulating drugs were more relaxed. For example, in the US, the government could only ban

6486-430: Is usually conducted in universities, medical schools, pharmaceutical companies, defense establishments, and commercial facilities that provide animal-testing services to the industry. The focus of animal testing varies on a continuum from pure research , focusing on developing fundamental knowledge of an organism, to applied research, which may focus on answering some questions of great practical importance, such as finding

6627-445: Is widespread in the animal kingdom...Pain is a stressor and, if not relieved, can lead to unacceptable levels of stress and distress in animals." The Guide states that the ability to recognize the symptoms of pain in different species is vital in efficiently applying pain relief and that it is essential for the people caring for and using animals to be entirely familiar with these symptoms. On the subject of analgesics used to relieve pain,

6768-808: The British Union for the Abolition of Vivisection by Cobbe in London in 1898; the Animal Welfare Board of India by Rukmini Devi Arundale in 1962; and People for the Ethical Treatment of Animals , co-founded by Ingrid Newkirk in 1980. In the Netherlands, Marianne Thieme and Esther Ouwehand were elected to parliament in 2006 representing the Parliamentary group for Animals. The preponderance of women in

6909-557: The Humane Society of the United States . The most common use of dogs is in the safety assessment of new medicines for human or veterinary use as a second species following testing in rodents, in accordance with the regulations set out in the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use . One of the most significant advancements in medical science involves

7050-551: The International Knockout Mouse Consortium , for example, aims to provide knockout mice for every gene in the mouse genome. In the U.S., Class A breeders are licensed by the U.S. Department of Agriculture (USDA) to sell animals for research purposes, while Class B dealers are licensed to buy animals from "random sources" such as auctions, pound seizure, and newspaper ads. Some Class B dealers have been accused of kidnapping pets and illegally trapping strays,

7191-587: The Sharia . This recognition is based on both the Qur'an and the Hadith . The Qur'an contains many references to animals, detailing that they have souls, form communities, communicate with God, and worship Him in their own way. Muhammad forbade his followers to harm any animal and asked them to respect animals' rights. Nevertheless, Islam does allow eating of certain species of animals. According to Christianity , all animals, from

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7332-540: The University Grants Commission to ban the use of live animals in universities and laboratories. Accurate global figures for animal testing are difficult to obtain; it has been estimated that 100 million vertebrates are experimented on around the world every year, 10–11 million of them in the EU. The Nuffield Council on Bioethics reports that global annual estimates range from 50 to 100 million animals. None of

7473-492: The University of Texas at El Paso states that the animal liberation movement, as characterized by the Animal Liberation Front and its various offshoots, "is a significant threat to global capital." ... Animal liberation challenges large sectors of the capitalist economy by assailing corporate agriculture and pharmaceutical companies and their suppliers. Far from being irrelevant to social movements, animal rights can form

7614-521: The dissection of live animals. The term is occasionally used to refer pejoratively to any experiment using living animals; for example, the Encyclopædia Britannica defines "vivisection" as: "Operation on a living animal for experimental rather than healing purposes; more broadly, all experimentation on live animals", although dictionaries point out that the broader definition is "used only by people who are opposed to such work". The word has

7755-728: The genome of mice. This genetic research progressed rapidly and, in 1996, Dolly the sheep was born, the first mammal to be cloned from an adult cell. Other 20th-century medical advances and treatments that relied on research performed in animals include organ transplant techniques, the heart-lung machine, antibiotics , and the whooping cough vaccine. Treatments for animal diseases have also been developed, including for rabies , anthrax , glanders , feline immunodeficiency virus (FIV), tuberculosis , Texas cattle fever, classical swine fever (hog cholera), heartworm , and other parasitic infections . Animal experimentation continues to be required for biomedical research, and

7896-412: The 17th-century French philosopher, René Descartes , who argued that animals do not experience pain and suffering because they lack consciousness . Bernard Rollin of Colorado State University , the principal author of two U.S. federal laws regulating pain relief for animals, writes that researchers remained unsure into the 1980s as to whether animals experience pain, and that veterinarians trained in

8037-529: The 18th and 19th centuries included Antoine Lavoisier 's use of a guinea pig in a calorimeter to prove that respiration was a form of combustion, and Louis Pasteur 's demonstration of the germ theory of disease in the 1880s using anthrax in sheep. Robert Koch used animal testing of mice and guinea pigs to discover the bacteria that cause anthrax and tuberculosis . In the 1890s, Ivan Pavlov famously used dogs to describe classical conditioning . Research using animal models has been central to most of

8178-408: The 1940s, Jonas Salk used rhesus monkey studies to isolate the most virulent forms of the polio virus, which led to his creation of a polio vaccine . The vaccine, which was made publicly available in 1955, reduced the incidence of polio 15-fold in the United States over the following five years. Albert Sabin improved the vaccine by passing the polio virus through animal hosts, including monkeys;

8319-460: The 20th and 21st centuries, and by one estimate, the number of mice and rats used in the United States alone in 2001 was 80 million. In 2013, it was reported that mammals (mice and rats), fish, amphibians, and reptiles together accounted for over 85% of research animals. In 2022, a law was passed in the United States that eliminated the FDA requirement that all drugs be tested on animals. Animal testing

8460-411: The British philosopher, argued that rights imply obligations. Every legal privilege, he wrote, imposes a burden on the one who does not possess that privilege: that is, "your right may be my duty." Scruton therefore regarded the emergence of the animal rights movement as "the strangest cultural shift within the liberal worldview", because the idea of rights and responsibilities is, he argued, distinctive to

8601-524: The Cartesian view of animals. Darwin noted the mental and emotional continuity between humans and animals, suggesting the possibility of animal suffering. The anti-vivisection movement emerged in the late 19th and early 20th centuries, driven significantly by women. From the 1970s onward, growing scholarly and activist interest in animal treatment has aimed to raise awareness and reform laws to improve animal rights and human–animal relationships. For some

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8742-629: The Law (1995) was the first extensive jurisprudential treatment of animal rights. In it, Francione compares the situation of animals to the treatment of slaves in the United States , where legislation existed that appeared to protect them while the courts ignored that the institution of slavery itself rendered the protection unenforceable. He offers as an example the United States Animal Welfare Act , which he describes as an example of symbolic legislation, intended to assuage public concern about

8883-591: The Sabin vaccine was produced for mass consumption in 1963, and had virtually eradicated polio in the United States by 1965. It has been estimated that developing and producing the vaccines required the use of 100,000 rhesus monkeys, with 65 doses of vaccine produced from each monkey. Sabin wrote in 1992, "Without the use of animals and human beings, it would have been impossible to acquire the important knowledge needed to prevent much suffering and premature death not only among humans, but also among animals." On 3 November 1957,

9024-560: The Seventh Circuit debated the issue of animal rights in 2001 with Peter Singer. Posner posits that his moral intuition tells him "that human beings prefer their own. If a dog threatens a human infant, even if it requires causing more pain to the dog to stop it, than the dog would have caused to the infant, then we favour the child. It would be monstrous to spare the dog." Singer challenges this by arguing that formerly unequal rights for gays, women, and certain races were justified using

9165-433: The U.S. before 1989 were simply taught to ignore animal pain. In his interactions with scientists and other veterinarians, he was regularly asked to "prove" that animals are conscious, and to provide "scientifically acceptable" grounds for claiming that they feel pain. Carbone writes that the view that animals feel pain differently is now a minority view. Academic reviews of the topic are more equivocal, noting that although

9306-597: The U.S. in 2014 including 929 who were caught in the wild. Most of the NHPs used in experiments are macaques ; but marmosets , spider monkeys , and squirrel monkeys are also used, and baboons and chimpanzees are used in the US. As of 2015 , there are approximately 730 chimpanzees in U.S. laboratories. In a survey in 2003, it was found that 89% of singly-housed primates exhibited self-injurious or abnormal stereotypyical behaviors including pacing, rocking, hair pulling, and biting among others. The first transgenic primate

9447-414: The UK in 2004. Albino rabbits are used in eye irritancy tests ( Draize test ) because rabbits have less tear flow than other animals, and the lack of eye pigment in albinos make the effects easier to visualize. The numbers of rabbits used for this purpose has fallen substantially over the past two decades. In 1996, there were 3,693 procedures on rabbits for eye irritation in the UK, and in 2017 this number

9588-568: The UK, just 198 procedures were carried out on cats in 2017. The number has been around 200 for most of the last decade. The regulations that apply to animals in laboratories vary across species. In the U.S., under the Animal Welfare Act and the Guide for the Care and Use of Laboratory Animals (the Guide ), published by the National Academy of Sciences, any procedure can be performed on an animal if it can be successfully argued that it

9729-413: The US before 1989 were taught to ignore pain, he writes, and at least one major veterinary hospital in the 1960s did not stock narcotic analgesics for animal pain control. In his interactions with scientists, he was often asked to "prove" that animals are conscious, and to provide "scientifically acceptable" evidence that they could feel pain. Scientific publications have made it clear since the 1980s that

9870-552: The US in 2016. A 2015 article published in the Journal of Medical Ethics , argued that the use of animals in the US has dramatically increased in recent years. Researchers found this increase is largely the result of an increased reliance on genetically modified mice in animal studies. In 1995, researchers at Tufts University Center for Animals and Public Policy estimated that 14–21 million animals were used in American laboratories in 1992,

10011-506: The USDA, in 2016 501,560 animals (61%) (not including rats, mice, birds, or invertebrates) were used in procedures that did not include more than momentary pain or distress. 247,882 (31%) animals were used in procedures in which pain or distress was relieved by anesthesia, while 71,370 (9%) were used in studies that would cause pain or distress that would not be relieved. The idea that animals might not feel pain as human beings feel it traces back to

10152-496: The USDA, whereas Public Health Service regulations are enforced by OLAW and in many cases by AAALAC. According to the 2014 U.S. Department of Agriculture Office of the Inspector General (OIG) report—which looked at the oversight of animal use during a three-year period—"some Institutional Animal Care and Use Committees ...did not adequately approve, monitor, or report on experimental procedures on animals". The OIG found that "as

10293-539: The Western world, Aristotle viewed animals as lacking reason and existing for human use, though other ancient philosophers believed animals deserved gentle treatment. Major religious traditions, chiefly Indian or Dharmic religions , opposed animal cruelty. While scholars like Descartes saw animals as unconscious automata and Kant denied direct duties to animals, Jeremy Bentham emphasized their capacity to suffer. The publications of Charles Darwin eventually eroded

10434-628: The ability to initiate action in pursuit of their desires and goals; a psychophysical identity over time; and an individual welfare in the sense that their experiential life fares well or ill for them, logically independently of their utility for others and logically independently of their being the object of anyone else's interests. Whereas Singer is primarily concerned with improving the treatment of animals and accepts that, in some hypothetical scenarios, individual animals might be used legitimately to further human or nonhuman ends, Regan believes we ought to treat nonhuman animals as we would humans. He applies

10575-544: The ability to suffer, nothing more, and once it is established that a being has interests, those interests must be given equal consideration. Singer quotes the English philosopher Henry Sidgwick (1838–1900): "The good of any one individual is of no more importance, from the point of view ... of the Universe, than the good of any other." Singer argues that equality of consideration is a prescription, not an assertion of fact: if

10716-454: The achievements of modern medicine. It has contributed most of the basic knowledge in fields such as human physiology and biochemistry , and has played significant roles in fields such as neuroscience and infectious disease . For example, the results have included the near- eradication of polio and the development of organ transplantation , and have benefited both humans and animals. From 1910 to 1927, Thomas Hunt Morgan 's work with

10857-500: The animal has been lawfully imported and is not a wild animal or a stray. The latter requirement may also be exempted by special arrangement. In 2010 the Directive was revised with EU Directive 2010/63/EU . In the UK, most animals used in experiments are bred for the purpose under the 1988 Animal Protection Act, but wild-caught primates may be used if exceptional and specific justification can be established. The United States also allows

10998-565: The animal rights movement; indeed, the terms "animal protection" and "protectionism" are increasingly favored. His position in 1996 was that there is no animal rights movement in the United States. Mark Rowlands , professor of philosophy at the University of Florida, has proposed a contractarian approach, based on the original position and the veil of ignorance —a "state of nature" thought experiment that tests intuitions about justice and fairness—in John Rawls 's A Theory of Justice (1971). In

11139-503: The argument that animals have at least simple conscious thoughts and feelings has strong support, some critics continue to question how reliably animal mental states can be determined. However, some canine experts are stating that, while intelligence does differ animal to animal, dogs have the intelligence of a two to two-and-a-half-year old. This does support the idea that dogs, at the very least, have some form of consciousness. The ability of invertebrates to experience pain and suffering

11280-531: The attitude of individuals regarding the treatment of animals and animal rights. These include gender, age, occupation, religion, and level of education. There has also been evidence to suggest that prior experience with pets may be a factor in people's attitudes. According to some studies, women are more likely to empathize with the cause of animal rights than men. A 1996 study suggested that factors that may partially explain this discrepancy include attitudes towards feminism and science, scientific literacy, and

11421-530: The basis for a broad coalition of progressive social groups and drive changes that strike at the heart of capitalist exploitation of animals, people and the earth. R. G. Frey , professor of philosophy at Bowling Green State University, is a preference utilitarian. In his early work, Interests and Rights (1980), Frey disagreed with Singer—who wrote in Animal Liberation (1975) that the interests of nonhuman animals must be given equal consideration when judging

11562-483: The basis of animal rights is in religion or animal worship (or in general nature worship ), with some religions banning killing any animal. In other religions animals are considered unclean . Hindu and Buddhist societies abandoned animal sacrifice and embraced vegetarianism from the 3rd century BCE. One of the most important sanctions of the Jain , Hindu, and Buddhist faiths is the concept of ahimsa , or refraining from

11703-845: The best model of inherited human disease and share 95% of their genes with humans. With the advent of genetic engineering technology, genetically modified mice can be generated to order and can provide models for a range of human diseases. Rats are also widely used for physiology, toxicology and cancer research, but genetic manipulation is much harder in rats than in mice, which limits the use of these rodents in basic science. Dogs are widely used in biomedical research, testing, and education—particularly beagles , because they are gentle and easy to handle, and to allow for comparisons with historical data from beagles (a Reduction technique). They are used as models for human and veterinary diseases in cardiology, endocrinology , and bone and joint studies, research that tends to be highly invasive, according to

11844-452: The better off. Another approach, virtue ethics , holds that in considering how to act we should consider the character of the actor, and what kind of moral agents we should be. Rosalind Hursthouse has suggested an approach to animal rights based on virtue ethics. Mark Rowlands has proposed a contractarian approach. Nussbaum (2004) writes that utilitarianism, starting with Jeremy Bentham and John Stuart Mill , has contributed more to

11985-399: The consequences of an act—on the grounds that animals have no interests. Frey argues that interests are dependent on desire, and that no desire can exist without a corresponding belief. Animals have no beliefs, because a belief state requires the ability to hold a second-order belief—a belief about the belief—which he argues requires language: "If someone were to say, e.g. 'The cat believes that

12126-401: The delivery of antitoxin in the 1925 serum run to Nome . The success of animal studies in producing the diphtheria antitoxin has also been attributed as a cause for the decline of the early 20th-century opposition to animal research in the United States. Subsequent research in model organisms led to further medical advances, such as Frederick Banting 's research in dogs, which determined that

12267-516: The destruction of life. According to Buddhism, humans do not deserve preferential treatment over other living beings. The Dharmic interpretation of this doctrine prohibits the killing of any living being. These Indian religions' dharmic beliefs are reflected in the ancient Indian works of the Tolkāppiyam and Tirukkural , which contain passages that extend the idea of nonviolence to all living beings. In Islam, animal rights were recognized early by

12408-462: The disease process without the added risk of harming an actual human. The species of the model organism is usually chosen so that it reacts to disease or its treatment in a way that resembles human physiology as needed. Biological activity in a model organism does not ensure an effect in humans, and care must be taken when generalizing from one organism to another. However, many drugs, treatments and cures for human diseases are developed in part with

12549-469: The door is locked,' then that person is holding, as I see it, that the cat holds the declarative sentence 'The door is locked' to be true; and I can see no reason whatever for crediting the cat or any other creature which lacks language, including human infants, with entertaining declarative sentences." Carl Cohen , professor of philosophy at the University of Michigan, argues that rights holders must be able to distinguish between their own interests and what

12690-410: The equality of the sexes were based only on the idea that men and women were equally intelligent, we would have to abandon the practice of equal consideration if this were later found to be false. But the moral idea of equality does not depend on matters of fact such as intelligence, physical strength, or moral capacity. Equality therefore cannot be grounded on the outcome of scientific investigations into

12831-411: The experiment; however death is the endpoint of some procedures. The procedures conducted on animals in the UK in 2017 were categorised as: 43% (1.61 million) sub-threshold, 4% (0.14 million) non-recovery, 36% (1.35 million) mild, 15% (0.55 million) moderate, and 4% (0.14 million) severe. A 'severe' procedure would be, for instance, any test where death is the end-point or fatalities are expected, whereas

12972-582: The extension of basic legal rights and personhood to non-human animals. The animals most often considered in arguments for personhood are hominids . Some animal-rights academics support this because it would break the species barrier, but others oppose it because it predicates moral value on mental complexity rather than on sentience alone. As of November 2019 , 29 countries had enacted bans on hominoid experimentation ; Argentina has granted captive orangutans basic human rights since 2014. Outside of primates , animal-rights discussions most often address

13113-449: The extent to which it satisfies the preferences (interests) of those affected. His position is that there is no reason not to give equal consideration to the interests of human and nonhumans, though his principle of equality does not require identical treatment. A mouse and a man both have an interest in not being kicked, and there are no moral or logical grounds for failing to accord those interests equal weight. Interests are predicated on

13254-629: The figures include invertebrates such as shrimp and fruit flies. The USDA/APHIS has published the 2016 animal research statistics. Overall, the number of animals (covered by the Animal Welfare Act) used in research in the US ;rose 6.9% from 767,622 (2015) to 820,812 (2016). This includes both public and private institutions. By comparing with EU data, where all vertebrate species are counted, Speaking of Research estimated that around 12 million vertebrates were used in research in

13395-401: The fruit fly Drosophila melanogaster identified chromosomes as the vector of inheritance for genes. Drosophila became one of the first, and for some time the most widely used, model organisms, and Eric Kandel wrote that Morgan's discoveries "helped transform biology into an experimental science". D. melanogaster remains one of the most widely used eukaryotic model organisms. During

13536-430: The fruit fly immune system differs greatly from that of humans, and diseases in insects can be different from diseases in vertebrates; however, fruit flies and waxworms can be useful in studies to identify novel virulence factors or pharmacologically active compounds. Several invertebrate systems are considered acceptable alternatives to vertebrates in early-stage discovery screens. Because of similarities between

13677-563: The guidance of animal models. Treatments for animal diseases have also been developed, including for rabies , anthrax , glanders , feline immunodeficiency virus (FIV), tuberculosis , Texas cattle fever, classical swine fever (hog cholera), heartworm , and other parasitic infections . Animal experimentation continues to be required for biomedical research, and is used with the aim of solving medical problems such as Alzheimer's disease, AIDS, multiple sclerosis, spinal cord injury, many headaches, and other conditions in which there

13818-488: The heart-lung machine, antibiotics , and the whooping cough vaccine. Animal testing is widely used to aid in research of human disease when human experimentation would be unfeasible or unethical . This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution . Performing experiments in model organisms allows for better understanding

13959-463: The human brain without harming humans; comparative epidemiological studies among human populations; simulators and computer programs for teaching purposes; among others. The terms animal testing, animal experimentation, animal research , in vivo testing, and vivisection have similar denotations but different connotations . Literally, "vivisection" means "live sectioning" of an animal, and historically referred only to experiments that involved

14100-558: The human condition, and it makes no sense to spread them beyond our own species. He accused animal rights advocates of "pre-scientific" anthropomorphism , attributing traits to animals that are, he says, Beatrix Potter -like, where "only man is vile." It is within this fiction that the appeal of animal rights lies, he argued. The world of animals is non-judgmental, filled with dogs who return our affection almost no matter what we do to them, and cats who pretend to be affectionate when, in fact, they care only about themselves. It is, he argued,

14241-508: The innate immune system of insects and mammals, insects can replace mammals in some types of studies. Drosophila melanogaster and the Galleria mellonella waxworm have been particularly important for analysis of virulent traits of mammalian pathogens. Waxworms and other insects have also proven valuable for the identification of pharmaceutical compounds with favorable bioavailability. The decision to adopt such models generally involves accepting

14382-406: The intelligence of nonhumans. All that matters is whether they can suffer. Commentators on all sides of the debate now accept that animals suffer and feel pain, although it was not always so. Bernard Rollin , professor of philosophy, animal sciences, and biomedical sciences at Colorado State University, writes that Descartes's influence continued to be felt until the 1980s. Veterinarians trained in

14523-644: The isolates of pancreatic secretion could be used to treat dogs with diabetes . This led to the 1922 discovery of insulin (with John Macleod ) and its use in treating diabetes, which had previously meant death. John Cade 's research in guinea pigs discovered the anticonvulsant properties of lithium salts, which revolutionized the treatment of bipolar disorder , replacing the previous treatments of lobotomy or electroconvulsive therapy. Modern general anaesthetics, such as halothane and related compounds, were also developed through studies on model organisms, and are necessary for modern, complex surgical operations. In

14664-458: The late 19th century, Emil von Behring isolated the diphtheria toxin and demonstrated its effects in guinea pigs. He went on to develop an antitoxin against diphtheria in animals and then in humans, which resulted in the modern methods of immunization and largely ended diphtheria as a threatening disease. The diphtheria antitoxin is famously commemorated in the Iditarod race, which is modeled after

14805-591: The laws of the land and would probably get rougher sanctions than if it were a human. My point is that like laws govern all who interact within a society, rights are to be applied to all beings who interact within that society. This is not to say these rights endowed by humans are equivalent to those held by nonhuman animals, but rather that if humans possess rights then so must all those who interact with humans. In sum, Garry suggests that humans have obligations to nonhuman animals; animals do not, and ought not to, have uninfringible rights against humans. Women have played

14946-473: The majority of researchers do believe animals suffer and feel pain, though it continues to be argued that their suffering may be reduced by an inability to experience the same dread of anticipation as humans or to remember the suffering as vividly. The ability of animals to suffer, even it may vary in severity, is the basis for Singer's application of equal consideration. The problem of animal suffering, and animal consciousness in general, arose primarily because it

15087-701: The membership of the British RSPCA in 1900. The modern animal advocacy movement has a similar representation of women. They are not invariably in leadership positions: during the March for Animals in Washington, D.C., in 1990—the largest animal rights demonstration held until then in the United States—most of the participants were women, but most of the platform speakers were men. Nevertheless, several influential animal advocacy groups have been founded by women, including

15228-434: The mistreatment of animals, and in many countries there are laws that seem to reflect those concerns, "in practice the legal system allows any use of animals, however abhorrent." The law only requires that any suffering not be "unnecessary". In deciding what counts as "unnecessary", an animal's interests are weighed against the interests of human beings, and the latter almost always prevail. Francione's Animals, Property, and

15369-457: The monkey AIDS model, SIV . In 2008, a proposal to ban all primates experiments in the EU has sparked a vigorous debate. Over 500,000 fish and 9,000 amphibians were used in the UK in 2016. The main species used is the zebrafish, Danio rerio , which are translucent during their embryonic stage, and the African clawed frog, Xenopus laevis . Over 20,000 rabbits were used for animal testing in

15510-690: The moral rights of humans are based on their possession of certain cognitive abilities, and because these abilities are also possessed by at least some nonhuman animals, such animals must have the same moral rights as humans. Although only humans act as moral agents, both marginal-case humans, such as infants, and at least some nonhumans must have the status of "moral patients". Moral patients are unable to formulate moral principles, and as such are unable to do right or wrong, even though what they do may be beneficial or harmful. Only moral agents are able to engage in moral action. Animals for Regan have " intrinsic value " as subjects-of-a-life, and cannot be regarded as

15651-408: The movement has led to a body of academic literature exploring feminism and animal rights, such as feminism and vegetarianism or veganism , the oppression of women and animals, and the male association of women and animals with nature and emotion, rather than reason—an association that several feminist writers have embraced. Lori Gruen writes that women and animals serve the same symbolic function in

15792-463: The near- eradication of polio and the development of organ transplantation , and have benefited both humans and animals. From 1910 to 1927, Thomas Hunt Morgan 's work with the fruit fly Drosophila melanogaster identified chromosomes as the vector of inheritance for genes, and Eric Kandel wrote that Morgan's discoveries "helped transform biology into an experimental science". Research in model organisms led to further medical advances, such as

15933-415: The original position, individuals choose principles of justice (what kind of society to form, and how primary social goods will be distributed), unaware of their individual characteristics—their race, sex, class, or intelligence, whether they are able-bodied or disabled, rich or poor—and therefore unaware of which role they will assume in the society they are about to form. The idea is that, operating behind

16074-453: The presence of a greater emphasis on "nurturance or compassion" among women. A common misconception on the concept of animal rights is that its proponents want to grant non-human animals the exact same legal rights as humans, such as the right to vote . This is not the case, as the concept is that animals should have rights with equal consideration to their interests (for example, cats do not have any interest in voting, so they should not have

16215-451: The production of the diphtheria antitoxin and the 1922 discovery of insulin and its use in treating diabetes, which had previously meant death. Modern general anaesthetics such as halothane were also developed through studies on model organisms, and are necessary for modern, complex surgical operations. Other 20th-century medical advances and treatments that relied on research performed in animals include organ transplant techniques,

16356-415: The real distinction between persons and animals." Tom Regan countered this view of rights by distinguishing moral agents and moral patients. According to a paper published in 2000 by Harold Herzog and Lorna Dorr, previous academic surveys of attitudes towards animal rights have tended to suffer from small sample sizes and non-representative groups. However, a number of factors appear to correlate with

16497-407: The recognition of the moral status of animals than any other ethical theory. The utilitarian philosopher most associated with animal rights is Peter Singer, professor of bioethics at Princeton University . Singer is not a rights theorist, but uses the language of rights to discuss how we ought to treat individuals. He is a preference utilitarian , meaning that he judges the rightness of an act by

16638-522: The respondents who were strong Christian fundamentalists and believers in creationism were less likely to advocate for animal rights than those who were less fundamentalist in their beliefs. The findings extended previous research, such as a 1992 study which found that 48% of animal rights activists were atheists or agnostic . A 2019 study in The Washington Post found that those who have positive attitudes toward animal rights also tend to have

16779-406: The right to vote). A 2016 study found that support for animal testing may not be based on cogent philosophical rationales, and more open debate is warranted. A 2007 survey to examine whether or not people who believed in evolution were more likely to support animal rights than creationists and believers in intelligent design found that this was largely the case—according to the researchers,

16920-635: The same set of intuitions. Posner replies that equality in civil rights did not occur because of ethical arguments, but because facts mounted that there were no morally significant differences between humans based on race, sex, or sexual orientation that would support inequality. If and when similar facts emerge about humans and animals, the differences in rights will erode too. But facts will drive equality, not ethical arguments that run contrary to instinct, he argues. Posner calls his approach "soft utilitarianism", in contrast to Singer's "hard utilitarianism". He argues: The "soft" utilitarian position on animal rights

17061-476: The same time period, studies on mouse genetics in the laboratory of William Ernest Castle in collaboration with Abbie Lathrop led to generation of the DBA ("dilute, brown and non-agouti") inbred mouse strain and the systematic generation of other inbred strains. The mouse has since been used extensively as a model organism and is associated with many important biological discoveries of the 20th and 21st centuries. In

17202-537: The smallest to the largest, are cared for and loved. According to the Bible, "All these animals waited for the Lord, that the Lord might give them food at the hour. The Lord gives them, they receive; The Lord opens his hand, and they are filled with good things." It further says God "gave food to the animals, and made the crows cry." The two main philosophical approaches to animal ethics are utilitarian and rights-based. The former

17343-410: The status of mammals (compare charismatic megafauna ). Other animals (considered less sentient) have gained less attention— insects relatively little (outside Jainism ) and animal-like bacteria hardly any. The vast majority of animals have no legally recognised rights. Critics of animal rights argue that nonhuman animals are unable to enter into a social contract , and thus cannot have rights,

17484-520: The strict Kantian ideal (which Kant himself applied only to humans) that they ought never to be sacrificed as a means to an end, and must be treated as ends in themselves. Gary Francione, professor of law and philosophy at Rutgers Law School in Newark, is a leading abolitionist writer, arguing that animals need only one right, the right not to be owned. Everything else would follow from that paradigm shift . He writes that, although most people would condemn

17625-913: The study. The IACUCs regulate all vertebrates in testing at institutions receiving federal funds in the USA. Although the Animal Welfare Act does not include purpose-bred rodents and birds, these species are equally regulated under Public Health Service policies that govern the IACUCs. The Public Health Service policy oversees the Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). The CDC conducts infectious disease research on nonhuman primates, rabbits, mice, and other animals, while FDA requirements cover use of animals in pharmaceutical research. Animal Welfare Act (AWA) regulations are enforced by

17766-453: The three-year study found that animal-use committees that do not know the specifics of the university and personnel do not make the same approval decisions as those made by animal-use committees that do know the university and personnel. Specifically, blinded committees more often ask for more information rather than approving studies. Scientists in India are protesting a recent guideline issued by

17907-478: The total number of procedures conducted on animals in the respective countries. Zebrafish are commonly used for the basic study and development of various cancers . Used to explore the immune system and genetic strains. They are low in cost, small size, fast reproduction rate, and able to observe cancer cells in real time. Humans and zebrafish share neoplasm similarities which is why they are used for research. The National Library of Medicine shows many examples of

18048-492: The treatment of animals, but difficult to implement. He argues that a focus on animal welfare, rather than animal rights, may worsen the position of animals by making the public feel comfortable about using them and entrenching the view of them as property. He calls animal rights groups who pursue animal welfare issues, such as People for the Ethical Treatment of Animals , the " new welfarists ", arguing that they have more in common with 19th-century animal protectionists than with

18189-437: The types of cancer zebrafish are used in. The use of zebrafish have allowed them to find differences between MYC-driven pre-B vs T-ALL and be exploited to discover novel pre-B ALL therapies on acute lymphocytic leukemia . The National Library of Medicine also explains how a neoplasm is difficult to diagnose at an early stage. Understanding the molecular mechanism of digestive tract tumorigenesis and searching for new treatments

18330-627: The use of dogs has resulted in a definite improvement in the quality of life for both humans and animals. The U.S. Department of Agriculture's Animal Welfare Report shows that 60,979 dogs were used in USDA-registered facilities in 2016. In the UK, according to the UK Home Office, there were 3,847 procedures on dogs in 2017. Of the other large EU users of dogs, Germany conducted 3,976 procedures on dogs in 2016 and France conducted 4,204 procedures in 2016. In both cases this represents under 0.2% of

18471-456: The use of dogs in developing the answers to insulin production in the body for diabetics and the role of the pancreas in this process. They found that the pancreas was responsible for producing insulin in the body and that removal of the pancreas, resulted in the development of diabetes in the dog. After re-injecting the pancreatic extract (insulin), the blood glucose levels were significantly lowered. The advancements made in this research involving

18612-433: The use of wild-caught primates; between 1995 and 1999, 1,580 wild baboons were imported into the U.S. Most of the primates imported are handled by Charles River Laboratories or by Fortrea , which are very active in the international primate trade . The extent to which animal testing causes pain and suffering , and the capacity of animals to experience and comprehend them, is the subject of much debate. According to

18753-578: The veil of ignorance, they will choose a social contract in which there is basic fairness and justice for them no matter the position they occupy. Rawls did not include species membership as one of the attributes hidden from the decision-makers in the original position. Rowlands proposes extending the veil of ignorance to include rationality, which he argues is an undeserved property similar to characteristics including race, sex and intelligence. American philosopher Timothy Garry has proposed an approach that deems nonhuman animals worthy of prima facie rights. In

18894-694: The widespread acceptance of the 3Rs, many countries—including Canada, Australia, Israel, South Korea, and Germany—have reported rising experimental use of animals in recent years with increased use of mice and, in some cases, fish while reporting declines in the use of cats, dogs, primates, rabbits, guinea pigs, and hamsters. Along with other countries, China has also escalated its use of GM animals , resulting in an increase in overall animal use. Animals used by laboratories are largely supplied by specialist dealers. Sources differ for vertebrate and invertebrate animals. Most laboratories breed and raise flies and worms themselves, using strains and mutants supplied from

19035-514: The wild or purpose-bred. In the United States and China, most primates are domestically purpose-bred, whereas in Europe the majority are imported purpose-bred. The European Commission reported that in 2011, 6,012 monkeys were experimented on in European laboratories. According to the U.S. Department of Agriculture , there were 71,188 monkeys in U.S. laboratories in 2016. 23,465 monkeys were imported into

19176-545: The writings of the Greeks in the 2nd and 4th centuries BCE. Aristotle and Erasistratus were among the first to perform experiments on living animals. Galen , a 2nd-century Roman physician, performed post-mortem dissections of pigs and goats. Avenzoar , a 12th-century Arabic physician in Moorish Spain introduced an experimental method of testing surgical procedures before applying them to human patients. Discoveries in

19317-694: Was argued that animals have no language . Singer writes that, if language were needed to communicate pain, it would often be impossible to know when humans are in pain, though we can observe pain behavior and make a calculated guess based on it. He argues that there is no reason to suppose that the pain behavior of nonhumans would have a different meaning from the pain behavior of humans. Tom Regan, professor emeritus of philosophy at North Carolina State University, argues in The Case for Animal Rights (1983) that nonhuman animals are what he calls "subjects-of-a-life", and as such are bearers of rights. He writes that, because

19458-427: Was just 63. Rabbits are also frequently used for the production of polyclonal antibodies. Cats are most commonly used in neurological research. In 2016, 18,898 cats were used in the United States alone, around a third of which were used in experiments which have the potential to cause "pain and/or distress" though only 0.1% of cat experiments involved potential pain which was not relieved by anesthetics/analgesics. In

19599-624: Was presumed activists targeted a fisherman's potts in Cardigan and in Crymych , Wales . A large number of lobster fishermen's pots were damaged in Stranraer , Scotland , with graffiti left at the scene indicating the group had carried out the attacks. Animal rights Many advocates of animal rights oppose the assignment of moral value and fundamental protections on the basis of species membership alone. They consider this idea, known as speciesism ,

19740-486: Was produced in 2001, with the development of a method that could introduce new genes into a rhesus macaque . This transgenic technology is now being applied in the search for a treatment for the genetic disorder Huntington's disease . Notable studies on non-human primates have been part of the polio vaccine development, and development of Deep Brain Stimulation , and their current heaviest non-toxicological use occurs in

19881-851: Was replicated by researchers at the Oklahoma State University , who found similar results: 73% of respondents answered "yes" to the question "Were you aware that slaughterhouses are where livestock are killed and processed into meat, such that, without them, you would not be able to consume meat?" In the U.S., many public protest slaughters were held in the late 1960s and early 1970s by the National Farmers Organization . Protesting low prices for meat, farmers killed their animals in front of media representatives. The carcasses were wasted and not eaten. This effort backfired because it angered television audiences to see animals needlessly and wastefully killed. Animal testing This

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