1941
104-463: 1942 Second Sino-Japanese War Taishō period Shōwa period Asia-Pacific Mediterranean and Middle East Other campaigns Coups The Zhejiang-Jiangxi campaign or the Chekiang–Kiangsi campaign ( Japanese : 浙贛作戦, simplified Chinese : 浙赣战役 ; traditional Chinese : 浙赣戰役 ; pinyin : Zhè-Gàn Zhànyì ), also known as Operation Sei-go ( Japanese : せ号作戦),
208-705: A full-scale battle in which Beijing and its port city of Tianjin fell to invading Japanese forces (July–August 1937). , On 11 July, in accordance with the Goso conference, the Imperial Japanese Army General Staff authorized the deployment of an infantry division from the Chōsen Army , two combined brigades from the Kwantung Army and an air regiment composed of 18 squadrons as reinforcements to Northern China. By 20 July, total Japanese military strength in
312-561: A show trial for "crimes against humanity". Imperial General Headquarters was aware of possible air attacks from Chinese territory on Japan. Two days before the Doolittle Raid, Headquarters set up an operational plan with the goal of defeating Chinese forces and destroying air bases. The operation started on May 15, 1942, with 40 infantry battalions and 15–16 artillery battalions of the Imperial Japanese Army. The main force of
416-709: A campaign of sabotage and guerrilla warfare . In November 1939, Chinese nationalist forces launched a large scale winter offensive , and in August 1940, communist forces launched the Hundred Regiments Offensive in central China. In December 1941, Japan launched a surprise attack on Pearl Harbor and declared war on the United States. The US increased its aid to China under the Lend-Lease Act , becoming its main financial and military supporter. With Burma cut off,
520-530: A communist victory and the Proclamation of the People's Republic of China in 1949. In China, the war is most commonly known as the "War of Resistance against Japanese Aggression" ( simplified Chinese : 抗日战争 ; traditional Chinese : 抗日戰爭 ), and shortened to "Resistance against Japanese Aggression" ( Chinese : 抗日 ) or the "War of Resistance" (simplified Chinese: 抗战 ; traditional Chinese: 抗戰 ). It
624-427: A cough, pain in the chest, and haemoptysis. When a flea bites a human and contaminates the wound with regurgitated blood, the plague-causing bacteria are passed into the tissue. Y. pestis can reproduce inside cells, so even if phagocytosed , they can still survive. Once in the body, the bacteria can enter the lymphatic system , which drains interstitial fluid . Plague bacteria secrete several toxins , one of which
728-684: A demilitarized zone between the Great Wall and Beijing-Tianjin region. Japan aimed to create another buffer zone between Manchukuo and the Chinese Nationalist government in Nanjing. Japan increasingly exploited China's internal conflicts to reduce the strength of its fractious opponents. Even years after the Northern Expedition, the political power of the Nationalist government was limited to just
832-436: A patient with pneumonic plague and were not wearing adequate personal protective equipment. Antimicrobial postexposure prophylaxis also can be considered for laboratory workers accidentally exposed to infectious materials and people who had close (<6 feet) or direct contact with infected animals, such as veterinary staff, pet owners, and hunters. Specific recommendations on pre- and post-exposure prophylaxis are available in
936-405: A person receives antibiotics before a sample is collected for laboratory testing, they may have a false negative culture and a positive PCR result. Blood tests to detect antibodies against Y. pestis can also be used to diagnose plague, however, this requires taking blood samples at different periods to detect differences between the acute and convalescent phases of F1 antibody titres. In 2020,
1040-752: A result of Depression -era tariffs ), and a protective buffer state against the Soviet Union in Siberia . As a result, the Japanese Army was widely prevalent in Manchuria immediately following the Japanese victory in the Russo-Japanese War in 1905, where Japan gained significant territory in Manchuria. As a result of their strengthened position, by 1915 Japan had negotiated a significant amount of economic privilege in
1144-528: A result of its victory at the end of the war. Japan had also attempted to annex the Liaodong Peninsula following the war, though was forced to return it to China following an intervention by France , Germany , and Russia . The Qing dynasty was on the brink of collapse due to internal revolts and the imposition of the unequal treaties , while Japan had emerged as a great power through its modernization measures. In 1905, Japan successfully defeated
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#17328442564941248-549: A rise in the rodent population. A 21st-century study of a 1665 outbreak of plague in the village of Eyam in England's Derbyshire Dales – which isolated itself during the outbreak, facilitating modern study – found that three-quarters of cases are likely to have been due to human-to-human transmission, especially within families, a much larger proportion than previously thought. Symptoms of plague are usually non-specific and to definitively diagnose plague, laboratory testing
1352-460: A study about rapid diagnostic tests that detect the F1 capsule antigen (F1RDT) by sampling sputum or bubo aspirate was released. Results show rapid diagnostic F1RDT test can be used for people who have suspected pneumonic and bubonic plague but cannot be used in asymptomatic people. F1RDT may be useful in providing a fast result for prompt treatment and fast public health response as studies suggest that F1RDT
1456-744: A term used mainly in foreign and Chinese narratives. The origins of the Second Sino-Japanese War can be traced back to the First Sino-Japanese War of 1894–1895, in which China, then under the rule of the Qing dynasty, was defeated by Japan and forced to cede Taiwan and recognize the full and complete independence of Korea in the Treaty of Shimonoseki . Japan also annexed the Senkaku Islands , which Japan claims were uninhabited, in early 1895 as
1560-640: A testing zone for advanced biplane and new-generation monoplane combat-aircraft designs. The introduction of the advanced A5M "Claude" fighters into the Shanghai-Nanjing theater of operations, beginning on 18 September 1937, helped the Japanese achieve a certain level of air superiority . However the few experienced Chinese veteran pilots, as well as several Chinese-American volunteer fighter pilots, including Maj. Art Chin , Maj. John Wong Pan-yang , and Capt. Chan Kee-Wong, even in their older and slower biplanes, proved more than able to hold their own against
1664-511: Is a period of "total" war. This view of a fourteen-year war has political significance because it provides more recognition for the role of northeast China in the War of Resistance. On the night of 7 July 1937, Chinese and Japanese troops exchanged fire in the vicinity of the Marco Polo (or Lugou) Bridge , a crucial access-route to Beijing. What began as confused, sporadic skirmishing soon escalated into
1768-528: Is about 10% while without it is about 70%. Globally, about 600 cases are reported a year. In 2017, the countries with the most cases include the Democratic Republic of the Congo , Madagascar and Peru . In the United States, infections occasionally occur in rural areas, where the bacteria are believed to circulate among rodents . It has historically occurred in large outbreaks , with the best known being
1872-523: Is highly sensitive for both pneumonic and bubonic plague. However, when using the rapid test, both positive and negative results need to be confirmed to establish or reject the diagnosis of a confirmed case of plague and the test result needs to be interpreted within the epidemiological context as study findings indicate that although 40 out of 40 people who had the plague in a population of 1000 were correctly diagnosed, 317 people were diagnosed falsely as positive. Bacteriologist Waldemar Haffkine developed
1976-872: Is known in China as the War of Resistance against Japanese Aggression ( simplified Chinese : 抗日战争 ; traditional Chinese : 抗日戰爭 ). On 18 September 1931, the Japanese staged the Mukden incident , a false flag event fabricated to justify their invasion of Manchuria and establishment of the puppet state of Manchukuo . This is sometimes marked as the beginning of the war. From 1931 to 1937, China and Japan engaged in skirmishes, including in Shanghai and in Northern China. Chinese Nationalist and Communist forces, respectively led by Chiang Kai-shek and Mao Zedong , had fought each other in
2080-410: Is known to cause beta-adrenergic blockade . Y. pestis spreads through the lymphatic vessels of the infected human until it reaches a lymph node , where it causes acute lymphadenitis . The swollen lymph nodes form the characteristic buboes associated with the disease, and autopsies of these buboes have revealed them to be mostly hemorrhagic or necrotic . If the lymph node is overwhelmed,
2184-613: Is most commonly used because of its perceived objectivity. When the invasion of China proper began in earnest in July 1937 near Beijing , the government of Japan used "The North China Incident" (Japanese: 北支事變/華北事變 , romanized: Hokushi Jihen/Kahoku Jihen ), and with the outbreak of the Battle of Shanghai the following month, it was changed to "The China Incident" (Japanese: 支那事變 , romanized: Shina Jihen ). The word "incident" (Japanese: 事變 , romanized: jihen )
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#17328442564942288-414: Is not considered necessary as long as standard and droplet precautions can be maintained. In cases of surgical mask shortages, patient overcrowding, poor ventilation in hospital wards, or other crises, pre-exposure prophylaxis might be warranted if sufficient supplies of antimicrobials are available. Postexposure prophylaxis should be considered for people who had close (<6 feet), sustained contact with
2392-469: Is not possible (such as some disaster areas). A systematic review by the Cochrane Collaboration found no studies of sufficient quality to make any statement on the efficacy of the vaccine. Diagnosing plague early leads to a decrease in transmission or spread of the disease. Pre-exposure prophylaxis for first responders and health care providers who will care for patients with pneumonic plague
2496-457: Is possible by any of the following means: Yersinia pestis circulates in animal reservoirs, particularly in rodents, in the natural foci of infection found on all continents except Australia. The natural foci of plague are situated in a broad belt in the tropical and sub-tropical latitudes and the warmer parts of the temperate latitudes around the globe, between the parallels 55° N and 40° S. Contrary to popular belief, rats did not directly start
2600-630: Is recorded to have died of such contamination while engaging in warfare against the Xiongnu. Plague victims were also reported to have been tossed by catapult into cities under siege. In 1347, the Genoese possession of Caffa , a great trade emporium on the Crimean peninsula , came under siege by an army of Mongol warriors of the Golden Horde under the command of Jani Beg . After a protracted siege during which
2704-410: Is required. Y. pestis can be identified through both a microscope and by culturing a sample and this is used as a reference standard to confirm that a person has a case of plague. The sample can be obtained from the blood, mucus ( sputum ), or aspirate extracted from inflamed lymph nodes ( buboes ). If a person is administered antibiotics before a sample is taken or if there is a delay in transporting
2808-468: Is short, usually two to four days, but sometimes just a few hours. The initial signs are indistinguishable from several other respiratory illnesses; they include headache, weakness, and spitting or vomiting of blood. The course of the disease is rapid; unless diagnosed and treated soon enough, typically within a few hours, death may follow in one to six days; in untreated cases, mortality is nearly 100%. Transmission of Y. pestis to an uninfected individual
2912-404: Is typically by finding the bacterium in fluid from a lymph node, blood or sputum . Those at high risk may be vaccinated . Those exposed to a case of pneumonic plague may be treated with preventive medication. If infected, treatment is with antibiotics and supportive care . Typically antibiotics include a combination of gentamicin and a fluoroquinolone . The risk of death with treatment
3016-671: The Black Death in the 14th century, which resulted in more than 50 million deaths in Europe. There are several different clinical manifestations of plague. The most common form is bubonic plague, followed by septicemic and pneumonic plague. Other clinical manifestations include plague meningitis, plague pharyngitis, and ocular plague. General symptoms of plague include fever, chills, headaches, and nausea. Many people experience swelling in their lymph nodes if they have bubonic plague. For those with pneumonic plague, symptoms may (or may not) include
3120-638: The Central Plains War broke out across China, involving regional commanders who had fought in alliance with the Kuomintang during the Northern Expedition, and the Nanjing government under Chiang. The Chinese Communist Party (CCP) previously fought openly against the Nanjing government after the Shanghai massacre of 1927 , and they continued to expand during this protracted civil war. The Kuomintang government in Nanjing decided to focus their efforts on suppressing
3224-639: The Chinese Civil War since 1927. In late 1933, Chiang Kai-shek encircled the Chinese Communists in an attempt to finally destroy them, forcing the Communists into the Long March , resulting in the Communists losing around 90% of their men. As a Japanese invasion became imminent, Chiang still refused to form a united front before he was placed under house arrest by his subordinates who forced him to form
Zhejiang-Jiangxi campaign - Misplaced Pages Continue
3328-464: The Democratic Republic of the Congo , Madagascar and Peru . It has historically occurred in large outbreaks , with the best known being the Black Death in the 14th century which resulted in more than 50 million dead. In recent years, cases have been distributed between small seasonal outbreaks which occur primarily in Madagascar, and sporadic outbreaks or isolated cases in endemic areas. In 2022
3432-778: The German Empire 's sphere of influence in Shandong province, leading to nationwide anti-Japanese protests and mass demonstrations in China. The country remained fragmented under the Beiyang Government and was unable to resist foreign incursions. For the purpose of unifying China and defeating the regional warlords, the Kuomintang (KMT) in Guangzhou launched the Northern Expedition from 1926 to 1928 with limited assistance from
3536-830: The Mukden incident in September 1931. Japanese soldiers set off a bomb on the Southern Manchurian Railroad in order to provoke an opportunity to act in "self defense" and invade outright. Japan charged that its rights in Manchuria, which had been established as a result of its victory in 1905 at the end of the Russo-Japanese War , had been systematically violated and there were "more than 120 cases of infringement of rights and interests, interference with business, boycott of Japanese goods, unreasonable taxation, detention of individuals, confiscation of properties, eviction, demand for cessation of business, assault and battery, and
3640-571: The Neutrality Acts of the 1930s . In addition, due to China's fractured political status, Japan often claimed that China was no longer a recognizable political entity on which war could be declared. In Japanese propaganda , the invasion of China became a crusade (Japanese: 聖戦 , romanized: seisen ), the first step of the "eight corners of the world under one roof" slogan (Japanese: 八紘一宇 , romanized: Hakkō ichiu ). In 1940, Japanese Prime Minister Fumimaro Konoe launched
3744-519: The Russian Empire in the Russo-Japanese War , gaining Tailen and southern Sakhalin and establishing a protectorate over Korea. In 1911, factions of the Qing Army uprose against the government, staging a revolution that swept across China's southern provinces. The Qing responded by appointing Yuan Shikai , commander of the loyalist Beiyang Army , as temporary prime minister in order to subdue
3848-622: The Second United Front in late 1936 in order to resist the Japanese invasion together. The full-scale war began on 7 July 1937 with the Marco Polo Bridge incident near Beijing , which prompted a full-scale Japanese invasion of the rest of China. The Japanese captured the capital of Nanjing in 1937 and perpetrated the Nanjing Massacre . After failing to stop the Japanese capture of Wuhan in 1938, then China's de facto capital at
3952-644: The Shanghai French Concession , areas which were outside of China's control due to the treaty port system. Japan moved into these areas after its 1941 declaration of war against the United States and the United Kingdom. Building on the hard-won victory in Shanghai, the IJA advanced on and captured the KMT capital city of Nanjing (December 1937) and Northern Shanxi (September – November 1937). Upon
4056-588: The Soviet Union . The National Revolutionary Army (NRA) formed by the Kuomintang swept through southern and central China until it was checked in Shandong, where confrontations with the Japanese garrison escalated into armed conflict. The conflicts were collectively known as the Jinan incident of 1928, during which time the Japanese military killed several Chinese officials and fired artillery shells into Jinan. According to
4160-714: The Taisei Yokusankai . When both sides formally declared war in December 1941, the name was replaced by " Greater East Asia War " (Japanese: 大東亞戰爭 , romanized: Daitōa Sensō ). Although the Japanese government still uses the term "China Incident" in formal documents, the word Shina is considered derogatory by China and therefore the media in Japan often paraphrase with other expressions like "The Japan–China Incident" (Japanese: 日華事變/日支事變 , romanized: Nikka Jiken/Nisshi Jiken ), which were used by media as early as
4264-517: The Tokyo tribunal by Douglas MacArthur but 12 of them were prosecuted in the Khabarovsk War Crime Trials in 1949 during which some admitted having spread bubonic plague within a 36-kilometre (22 mi) radius around the city of Changde . Ishii innovated bombs containing live mice and fleas, with very small explosive loads, to deliver the weaponized microbes, overcoming the problem of
Zhejiang-Jiangxi campaign - Misplaced Pages Continue
4368-861: The United States Army Air Forces airlifted material over the Himalayas . In 1944, Japan launched Operation Ichi-Go , the invasion of Henan and Changsha . In 1945, the Chinese Expeditionary Force resumed its advance in Burma and completed the Ledo Road linking India to China. China launched large counteroffensives in South China and repulsed a failed Japanese invasion of West Hunan and recaptured Japanese occupied regions of Guangxi . Japan formally surrendered on 2 September 1945, following
4472-572: The atomic bombings of Hiroshima and Nagasaki , Soviet declaration of war and subsequent invasions of Manchukuo and Korea . The war resulted in the deaths of around 20 million people, mostly Chinese civilians. China was recognized as one of the Big Four Allies , regained all territories lost, and became one of the five permanent members of the United Nations Security Council . The Chinese Civil War resumed in 1946, ending with
4576-480: The 18 September 1931 Japanese invasion of Manchuria marks the start of the War of Resistance. Although not the conventional Western view, British historian Rana Mitter describes this Chinese trend of historical analysis as "perfectly reasonable". In 2017, the Chinese government officially announced that it would adopt this view. Under this interpretation, the 1931–1937 period is viewed as the "partial" war, while 1937–1945
4680-578: The 1921 and 1927 Imperial Eastern Region Conferences reconfirmed Japan's commitment to be the dominant power in the Northeast. The 1929 Red Army victory shook that policy to the core and reopened the Manchurian problem. By 1930, the Kwantung Army realized they faced a Red Army that was only growing stronger. The time to act was drawing near and Japanese plans to conquer the Northeast were accelerated. In 1930,
4784-572: The 1930s. The name "Second Sino-Japanese War" is not commonly used in Japan as the China it fought a war against in 1894 to 1895 was led by the Qing dynasty , and thus is called the Qing-Japanese War (Japanese: 日清戦争 , romanized: Nisshin–Sensō ), rather than the First Sino-Japanese War . Another term for the second war between Japan and China is the "Japanese invasion of China",
4888-454: The 1931 Japanese invasion of Manchuria . According to historian Rana Mitter , historians in China are unhappy with the blanket revision, and (despite sustained tensions) the Republic of China did not consider itself to be in an ongoing war with Japan over these six years. It is also referred to as part of the "Global Anti-Fascist War". In Japan, nowadays, the name "Japan–China War" ( Japanese : 日中戦争 , romanized : Nitchū Sensō )
4992-399: The 1937 " Sword March ", which—with slightly reworked lyrics—became the National Revolutionary Army's standard marching cadence and popularized the racial epithet guizi to describe the Japanese invaders. The Imperial General Headquarters (GHQ) in Tokyo, content with the gains acquired in northern China following the Marco Polo Bridge Incident, initially showed reluctance to escalate
5096-422: The Beijing-Tianjin area exceeded 180,000 personnel. The Japanese gave Sung and his troops "free passage" before moving in to pacify resistance in areas surrounding Beijing (then Beiping) and Tianjin. After 24 days of combat, the Chinese 29th Army was forced to withdraw. The Japanese captured Beijing and the Taku Forts at Tianjin on 29 and 30 July respectively, thus concluding the Beijing-Tianjin campaign. However,
5200-421: The Centers for Disease Control and Prevention in 2021. The plague bacterium could develop drug resistance and again become a major health threat. One case of a drug-resistant form of the bacterium was found in Madagascar in 1995. Further outbreaks in Madagascar were reported in November 2014 and October 2017. Globally about 600 cases are reported a year. In 2017, the countries with the most cases include
5304-400: The Chinese Communists through the Encirclement Campaigns , following the policy of "first internal pacification, then external resistance" (Chinese: 攘外必先安內 ). The internecine warfare in China provided excellent opportunities for Japan, which saw Manchuria as a limitless supply of raw materials, a market for its manufactured goods (now excluded from the markets of many Western countries as
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#17328442564945408-469: The Chinese to deploy troops in their own city. In Manchukuo there was an ongoing campaign to pacify the Anti-Japanese Volunteer Armies that arose from widespread outrage over the policy of non-resistance to Japan. On 15 April 1932, the Chinese Soviet Republic led by the Communists declared war on Japan. In 1933, the Japanese attacked the Great Wall region. The Tanggu Truce established in its aftermath, gave Japan control of Rehe Province , as well as
5512-489: The Japanese Army had been given orders not to advance further than the Yongding River. In a sudden volte-face , the Konoe government's foreign minister opened negotiations with Chiang Kai-shek's government in Nanjing and stated: "Japan wants Chinese cooperation, not Chinese land." Nevertheless, negotiations failed to move further. The Ōyama Incident on 9 August escalated the skirmishes and battles into full scale warfare. The 29th Army's resistance (and poor equipment) inspired
5616-472: The Japanese army was ordered to retreat, and the Chinese army followed and pursued them. By the end of September, except for Jinhua, Wuyi and the northeastern region, all along the Zhejiang-Jiangxi Railway had been recovered. Japanese troops conducted a massive search for American airmen and in the process whole towns and villages that were suspected of harboring the Americans were burned to the ground and many civilians executed. The Japanese also wanted to occupy
5720-465: The Japanese intercepted most of the attack with A2N and A4N fighters from the aircraft carriers Hosho and Ryujo , shooting down several of the Chinese planes while losing a single A4N in the dogfight with Lt. Huang Xinrui in his P-26/281; the Japanese Army reinforcements succeeded in landing in northern Shanghai. The Imperial Japanese Army (IJA) ultimately committed over 300,000 troops, along with numerous naval vessels and aircraft, to capture
5824-468: The Japanese strongholds in Shanghai, leading to bitter street fighting. In an attack on the Japanese cruiser Izumo , Kuomintang planes accidentally bombed the Shanghai International Settlement , which led to more than 3,000 civilian deaths. In the three days from 14 August through 16, 1937, the Imperial Japanese Navy (IJN) sent many sorties of the then-advanced long-ranged G3M medium-heavy land-based bombers and assorted carrier-based aircraft with
5928-415: The Japanese-backed East Hebei Autonomous Council and the Hebei–Chahar Political Council were established. There in the empty space of Chahar the Mongol military government was formed on 12 May 1936. Japan provided all the necessary military and economic aid. Afterwards Chinese volunteer forces continued to resist Japanese aggression in Manchuria, and Chahar and Suiyuan . Some Chinese historians believe
6032-406: The League of Nations. No country took action against Japan beyond tepid censure. From 1931 until summer 1937, the Nationalist Army under Chiang Kai-shek did little to oppose Japanese encroachment into China. Incessant fighting followed the Mukden Incident. In 1932, Chinese and Japanese troops fought the January 28 Incident battle. This resulted in the demilitarization of Shanghai , which forbade
6136-428: The Mongol army was reportedly withering from the disease, they decided to use the infected corpses as a biological weapon. The corpses were catapulted over the city walls, infecting the inhabitants. This event might have led to the transfer of the Black Death via their ships into the south of Europe , possibly explaining its rapid spread. During World War II , the Japanese Army developed weaponized plague, based on
6240-502: The area of the Yangtze River Delta . Other sections of China were essentially in the hands of local Chinese warlords. Japan sought various Chinese collaborators and helped them establish governments friendly to Japan. This policy was called the Specialization of North China ( 華北特殊化 ; huáběitèshūhùa ), more commonly known as the North China Autonomous Movement. The northern provinces affected by this policy were Chahar , Suiyuan , Hebei , Shanxi , and Shandong. This Japanese policy
6344-607: The area to prevent American air force from ever using airfields in China that could put the Japanese mainland within reach. When Japanese troops moved out of the Zhejiang and Jiangxi areas in mid-August, they left behind a trail of devastation. The Japanese executed 250,000 civilians for helping the American fliers escape. The Imperial Japanese Army had also spread cholera , typhoid , plague -infected fleas and dysentery pathogens. The Japanese biological warfare Unit 731 brought almost 300 pounds of paratyphoid and anthrax to be left in contaminated food and contaminated wells with
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#17328442564946448-431: The bacterium, developing strains resistant to antibiotics, combining the bacterium with other diseases (such as diphtheria ), and genetic engineering. Scientists who worked in USSR bio-weapons programs have stated that the Soviet effort was formidable and that large stocks of weaponised plague bacteria were produced. Information on many of the Soviet and US projects is largely unavailable. Aerosolized pneumonic plague remains
6552-412: The body and possibly ischemic necrosis (tissue death due to lack of circulation/perfusion to that tissue) from the clots. DIC results in depletion of the body's clotting resources so that it can no longer control bleeding. Consequently, there is bleeding into the skin and other organs, which can cause red and/or black patchy rash and hemoptysis/hematemesis (coughing up/ vomiting of blood). There are bumps on
6656-414: The breeding and release of large numbers of fleas. During the Japanese occupation of Manchuria , Unit 731 deliberately infected Chinese , Korean and Manchurian civilians and prisoners of war with the plague bacterium. These subjects, termed "maruta" or "logs", were then studied by dissection , others by vivisection while still conscious. Members of the unit such as Shiro Ishii were exonerated from
6760-422: The buildings. Plague (disease) This is an accepted version of this page Plague is an infectious disease caused by the bacterium Yersinia pestis . Symptoms include fever , weakness and headache . Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms. Pneumonic plague infects
6864-404: The capture of Nanjing, Japanese committed massive war atrocities including mass murder and rape of Chinese civilians after 13 December 1937, which has been referred to as the Nanjing Massacre . Over the next several weeks, Japanese troops perpetrated numerous mass executions and tens of thousands of rapes. The army looted and burned the surrounding towns and the city, destroying more than a third of
6968-411: The city's large foreign community and increase China's foreign support. On 13 August 1937, Kuomintang soldiers attacked Japanese Marine positions in Shanghai, with Japanese army troops and marines in turn crossing into the city with naval gunfire support at Zhabei , leading to the Battle of Shanghai. On 14 August, Chinese forces under the command of Zhang Zhizhong were ordered to capture or destroy
7072-402: The city. After more than three months of intense fighting, their casualties far exceeded initial expectations. On 26 October, the IJA captured Dachang, a key strong-point within Shanghai, and on 5 November, additional reinforcements from Japan landed in Hangzhou Bay. Finally, on 9 November, the NRA began a general retreat. Japan did not immediately occupy the Shanghai International Settlement or
7176-484: The clinical guidelines on treatment and prophylaxis of plague published in 2021. If diagnosed in time, the various forms of plague are usually highly responsive to antibiotic therapy. The antibiotics often used are streptomycin , chloramphenicol and tetracycline . Amongst the newer generation of antibiotics, gentamicin and doxycycline have proven effective in monotherapeutic treatment of plague. Guidelines on treatment and prophylaxis of plague were published by
7280-466: The commander of Japanese forces involved in the massacre of the 250,000 Chinese civilians, was sentenced in 1948 in part due to his "failure to prevent atrocities". He was given a life sentence but was paroled in 1954 after only serving six years. On April 18, 1942, the United States launched the Doolittle Raid , an attack by 16 B-25 Mitchell bombers from the aircraft carrier USS Hornet on Tokyo , Nagoya , and Yokohama . The original plan
7384-452: The conflict into a full-scale war. Following the shooting of two Japanese officers who were attempting to enter the Hongqiao military airport on 9 August 1937, the Japanese demanded that all Chinese forces withdraw from Shanghai; the Chinese outright refused to meet this demand. In response, both the Chinese and the Japanese marched reinforcements into the Shanghai area. Chiang concentrated his best troops north of Shanghai in an effort to impress
7488-508: The country. China was reduced to a fractured state. As a result, China's prosperity began to wither and its economy declined. This instability presented an opportunity for nationalistic politicians in Japan to press for territorial expansion. In 1915, Japan issued the Twenty-One Demands to extort further political and commercial privilege from China, which was accepted by the regime of Yuan Shikai. Following World War I , Japan acquired
7592-598: The country. Yuan's attempts at restoring the monarchy triggered the National Protection War , and Yuan Shikai was overthrown after only a few months. In the aftermath of Shikai's death in June 1916, control of China fell into the hands of the Beiyang Army leadership. The Beiyang government was a civilian government in name, but in practice it was a military dictatorship with a different warlord controlling each province of
7696-527: The expectation of destroying the Chinese Air Force . However, the Imperial Japanese Navy encountered unexpected resistance from the defending Chinese Curtiss Hawk II / Hawk III and P-26/281 Peashooter fighter squadrons; suffering heavy (50%) losses from the defending Chinese pilots (14 August was subsequently commemorated by the KMT as China's Air Force Day ). The skies of China had become
7800-454: The explosive killing the infected animal and insect by the use of a ceramic, rather than metal, casing for the warhead. While no records survive of the actual usage of the ceramic shells, prototypes exist and are believed to have been used in experiments during WWII. After World War II, both the United States and the Soviet Union developed means of weaponising pneumonic plague. Experiments included various delivery methods, vacuum drying, sizing
7904-631: The first plague vaccine in 1897. He conducted a massive inoculation program in British India , and it is estimated that 26 million doses of Haffkine's anti-plague vaccine were sent out from Bombay between 1897 and 1925, reducing the plague mortality by 50–85%. Since human plague is rare in most parts of the world as of 2023, routine vaccination is not needed other than for those at particularly high risk of exposure, nor for people living in areas with enzootic plague, meaning it occurs at regular, predictable rates in populations and specific areas, such as
8008-463: The flea, sticking together to form a plug that blocks its stomach and causes it to starve. The flea then bites a host and continues to feed, even though it cannot quell its hunger, and consequently, the flea vomits blood tainted with the bacteria back into the bite wound. The bubonic plague bacterium then infects a new person and the flea eventually dies from starvation. Serious outbreaks of plague are usually started by other disease outbreaks in rodents or
8112-422: The infection can pass into the bloodstream, causing secondary septicemic plague and if the lungs are seeded, it can cause secondary pneumonic plague . Lymphatics ultimately drain into the bloodstream, so the plague bacteria may enter the blood and travel to almost any part of the body. In septicemic plague, bacterial endotoxins cause disseminated intravascular coagulation (DIC), causing tiny clots throughout
8216-630: The investigation results of the Association of the Families of the Victims of the Jinan massacre, it showed that 6,123 Chinese civilians were killed and 1,701 injured. Relations between the Chinese Nationalist government and Japan severely worsened as a result of the Jinan incident. As the National Revolutionary Army approached Beijing, Zhang Zuolin decided to retreat back to Manchuria, before he
8320-437: The lungs, causing shortness of breath, coughing and chest pain; bubonic plague affects the lymph nodes , making them swell; and septicemic plague infects the blood and can cause tissues to turn black and die . The bubonic and septicemic forms are generally spread by flea bites or handling an infected animal, whereas pneumonic plague is generally spread between people through the air via infectious droplets. Diagnosis
8424-559: The oppression of Korean residents". After five months of fighting, Japan established the puppet state of Manchukuo in 1932, and installed the last Emperor of China, Puyi , as its puppet ruler. Militarily too weak to challenge Japan directly, China appealed to the League of Nations for help. The League's investigation led to the publication of the Lytton Report , condemning Japan for its incursion into Manchuria, causing Japan to withdraw from
8528-436: The person's sample to a laboratory and/or a poorly stored sample, there is a possibility for false negative results. Polymerase chain reaction (PCR) may also be used to diagnose plague, by detecting the presence of bacterial genes such as the pla gene (plasmogen activator) and caf1 gene, (F1 capsule antigen). PCR testing requires a very small sample and is effective for both alive and dead bacteria. For this reason, if
8632-616: The possible origin of all modern strands of Yersinia pestis DNA was found in human remains in three graves located in Kyrgyzstan , dated to 1338 and 1339. The siege of Caffa in Crimea in 1346, is known to have been the first plague outbreak with following strands, later to spread over Europe. Sequencing DNA compared to other ancient and modern strands paints a family tree of the bacteria. Bacteria today affecting marmots in Kyrgyzstan, are closest to
8736-524: The regiment, Commander Anan Weiji of the 11th Army, commanded two divisions and four detachments, advancing from east to west from Hangzhou and Nanchang to attack in the direction of Shangrao, Jiangxi. On May 15, the main force of the Japanese 13th Army invaded westward along the Zhejiang-Jiangxi Railway and both sides from Fenghua, Shangyu, Shaoxing, Xiaoshan and other towns in Zhejiang. On August 15,
8840-472: The region by pressuring Yuan Shikai , the president of the Republic of China at the time. With a widened range of economic privileges in Manchuria, Japan began focusing on developing and protecting matters of economic interests. This included railroads, businesses, natural resources, and a general control of the territory. With its influence growing, the Japanese Army began to justify its presence by stating that it
8944-454: The revolution. Yuan, wanting to remain in power, compromised with the revolutionaries, and agreed to abolish the monarchy and establish a new republican government, under the condition he be appointed president of China. The new Beiyang government of China was proclaimed in March 1912, after which Yuan Shikai began to amass power for himself. In 1913, the parliamentary political leader Song Jiaoren
9048-506: The skin that look somewhat like insect bites; these are usually red, and sometimes white in the centre. Untreated, the septicemic plague is usually fatal. Early treatment with antibiotics reduces the mortality rate to between 4 and 15 per cent. The pneumonic form of plague arises from infection of the lungs . It causes coughing and thereby produces airborne droplets that contain bacterial cells and are likely to infect anyone inhaling them. The incubation period for pneumonic plague
9152-557: The sleek A5Ms in dogfights , and it also proved to be a battle of attrition against the Chinese Air Force. At the start of the battle, the local strength of the NRA was around five divisions, or about 70,000 troops, while local Japanese forces comprised about 6,300 marines. On 23 August, the Chinese Air Force attacked Japanese troop landings at Wusongkou in northern Shanghai with Hawk III fighter-attack planes and P-26/281 fighter escorts, and
9256-400: The spread of the bubonic plague. It is mainly a disease in the fleas ( Xenopsylla cheopis ) that infested the rats, making the rats themselves the first victims of the plague. Rodent-borne infection in a human occurs when a person is bitten by a flea that has been infected by biting a rodent that itself has been infected by the bite of a flea carrying the disease. The bacteria multiply inside
9360-512: The strand found in the graves, suggesting this is also the location where plague transferred from animals to humans. The plague has a long history as a biological weapon . Historical accounts from ancient China and medieval Europe details the use of infected animal carcasses, such as cows or horses, and human carcasses, by the Xiongnu / Huns , Mongols , Turks and other groups, to contaminate enemy water supplies. Han dynasty general Huo Qubing
9464-541: The tensions in the Northeast that led to the Mukden Incident and eventually the Second Sino-Japanese War. The Soviet Red Army victory over Xueliang's forces not only reasserted Soviet control over the CER in Manchuria but revealed Chinese military weaknesses that Japanese Kwantung Army officers were quick to note. The Soviet Red Army performance also stunned the Japanese. Manchuria was central to Japan's East Asia policy. Both
9568-692: The time, the Nationalist government relocated to Chongqing in the Chinese interior. After the Sino-Soviet Non-Aggression Pact , Soviet aid bolstered the National Revolutionary Army and Air Force . By 1939, after Chinese victories at Changsha and with Japan's lines of communications stretched deep into the interior, the war reached a stalemate. The Japanese were unable to defeat Chinese Communist Party forces in Shaanxi , who waged
9672-524: The western United States. It is not even indicated for most travellers to countries with known recent reported cases, particularly if their travel is limited to urban areas with modern hotels. The United States CDC thus only recommends vaccination for (1) all laboratory and field personnel who are working with Y. pestis organisms resistant to antimicrobials: (2) people engaged in aerosol experiments with Y. pestis ; and (3) people engaged in field operations in areas with enzootic plague where preventing exposure
9776-402: The withdrawal of the army from areas around Yushan, Kinhwa and Futsin. This attack took place at Jinhua in Zhejiang and the Japanese soldiers inadvertently advanced in the area they spread with biological weapons and got themselves infected, leading to over 1,700 dying and 10,000 getting sick. Shunroku Hata , the commander of Japanese forces involved of the massacre of 250,000 Chinese civilians,
9880-539: Was assassinated by the Kwantung Army in 1928. His son, Zhang Xueliang , took over as the leader of the Fengtian clique in Manchuria. Later in the same year, Zhang declared his allegiance to the Nationalist government in Nanjing under Chiang Kai-shek , and consequently, China was nominally reunified under one government. The July–November 1929 conflict over the Chinese Eastern Railroad (CER) further increased
9984-589: Was a campaign by the China Expeditionary Army of the Imperial Japanese Army under Shunroku Hata and Chinese 3rd War Area forces under Gu Zhutong in Chinese provinces of Zhejiang and Jiangxi from mid May to early September 1942. Japanese troops used biological weapons against Chinese soldiers and civilians alike. Japanese soldiers also committed massacres throughout the battle, resulting in over 300,000 Chinese deaths. Shunroku Hata ,
10088-472: Was also called the "Eight Years' War of Resistance" (simplified Chinese: 八年抗战 ; traditional Chinese: 八年抗戰 ), but in 2017 the Chinese Ministry of Education issued a directive stating that textbooks were to refer to the war as the "Fourteen Years' War of Resistance" (simplified Chinese: 十四年抗战 ; traditional Chinese: 十四年抗戰 ), reflecting a focus on the broader conflict with Japan going back to
10192-406: Was assassinated ; it is generally believed Yuan Shikai ordered the assassination. Yuan Shikai then forced the parliament to pass a bill to strengthen the power of the president and sought to restore the imperial system , becoming the new emperor of China. However, there was little support for an imperial restoration among the general population, and protests and demonstrations soon broke out across
10296-579: Was for the aircraft to bomb Japan and land at airfields in unoccupied portion of China. Because the raid had to be launched earlier than planned, all but one of the aircraft (which against orders diverted to the Soviet Union) ran out of fuel and crashed in the Chinese provinces of Zhejiang and Jiangxi or their offshore islands. Sixty-four American airmen parachuted into the area around Zhejiang. Most were given shelter by Chinese civilians but eight Americans were captured by Japanese troops; three were shot after
10400-656: Was fought between the Republic of China and the Empire of Japan between 1937 and 1945, following a period of war localized to Manchuria that started in 1931. It is considered part of World War II , and often regarded as the beginning of World War II in Asia. It was the largest Asian war in the 20th century and has been described as "the Asian Holocaust ", in reference to the scale of Japanese war crimes against Chinese civilians. It
10504-571: Was most effective in the area of what is now Inner Mongolia and Hebei. In 1935, under Japanese pressure, China signed the He–Umezu Agreement , which forbade the KMT to conduct party operations in Hebei. In the same year, the Chin–Doihara Agreement was signed expelling the KMT from Chahar. Thus, by the end of 1935 the Chinese government had essentially abandoned northern China. In its place,
10608-490: Was sentenced 1948 in part due to his "failure to prevent atrocities". He was given a life sentence but was paroled in 1954. Second Sino-Japanese War [REDACTED] China [REDACTED] Japan [REDACTED] 14,000,000 total [REDACTED] 4,100,000 total Second Sino-Japanese War Taishō period Shōwa period Asia-Pacific Mediterranean and Middle East Other campaigns Coups The Second Sino-Japanese War
10712-453: Was simply protecting its own economic interests. However militarists in the Japanese Army began pushing for an expansion of influence, leading to the Japanese Army assassinating the warlord of Manchuria, Zhang Zuolin . This was done with hopes that it would start a crisis that would allow Japan to expand their power and influence in the region. When this was not as successful as they desired, Japan then decided to invade Manchuria outright after
10816-425: Was used by Japan, as neither country had made a formal declaration of war . From the Japanese perspective, localizing these conflicts was beneficial in preventing intervention from other countries, particularly the United Kingdom and the United States, which were its primary source of petroleum and steel respectively. A formal expression of these conflicts would potentially lead to an American embargo in accordance with
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