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William Harvey

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123-539: William Harvey (1 April 1578 – 3 June 1657) was an English physician who made influential contributions to anatomy and physiology . He was the first known physician to describe completely, and in detail, pulmonary and systemic circulation as well as the specific process of blood being pumped to the brain and the rest of the body by the heart (though earlier writers, such as Realdo Colombo , Michael Servetus , and Jacques Dubois , had provided precursors to some of his theories). William's father, Thomas Harvey,

246-663: A Roman garrison at Aballava , now Burgh-by-Sands , in Cumbria: a 4th-century inscription says that the Roman military unit "Numerus Maurorum Aurelianorum" ("unit of Aurelian Moors") from Mauretania (Morocco) was stationed there. Although the Roman Empire incorporated peoples from far and wide, genetic studies suggest the Romans did not significantly mix into the British population. The exact nature of

369-627: A geographic area brings protests, especially from the Scotch . However, although Taylor believed this blurring effect was dying out, in his book The Isles: A History (1999), Norman Davies lists numerous examples in history books of "British" still being used to mean "English" and vice versa. In December 2010, Matthew Parris in The Spectator , analysing the use of "English" over "British", argued that English identity, rather than growing, had existed all along but has recently been unmasked from behind

492-574: A great philosopher. He said of him "He writes philosophy like a Lord Chancellor." In 1628 he published in Frankfurt his completed treatise on the circulation of the blood, the De Motu Cordis . As a result of negative comments by other physicians Harvey "fell mightily in his practice", but continued advancing his career. He was re-elected 'Censor' of the College of Physicians in 1629, having been elected for

615-697: A greater extent than their white counterparts; however, groups such as the Campaign for an English Parliament (CEP) suggest the emergence of a broader civic and multi-ethnic English nationhood. Scholars and journalists have noted a rise in English self-consciousness, with increased use of the English flag , particularly at football matches where the Union flag was previously more commonly flown by fans. This perceived rise in English self-consciousness has generally been attributed to

738-444: A half an hour. All of these estimates were purposefully low, so that people could see the vast amount of blood Galen's theory required the liver to produce. He estimated that the capacity of the heart was 1.5 imperial fluid ounces (43  ml ), and that every time the heart pumps, 1 ⁄ 8 of that blood is expelled. This led to Harvey's estimate that about 1 ⁄ 6 imperial fluid ounce (4.7 ml) of blood went through

861-556: A large number of dissections ... of diseased bodies, with his observations on the development on insects, and a series of notes on comparative anatomy." During this period, Harvey maintained his position, helped the wounded on several occasions and protected the King's children during the Battle of Edgehill . The conflicts of the Civil War soon led King Charles to Oxford , with Harvey attending, where

984-450: A large statistical spread in all cases. However, the authors noted that the similarity observed between the various sample groups was likely to be due to more recent internal migration. Another 2016 study conducted using evidence from burials found in northern England, found that a significant genetic difference was present in bodies from the Iron Age and the Roman period on the one hand, and

1107-452: A lengthy pass through the lungs, during which it becomes red, and gets rid of the sooty fumes by the act of exhalation'. Ideas on circulation of blood were also proposed by the Spanish veterinarian-farrier Francisco de la Reyna in 1546. Pulmonary circulation was described by Renaldus Columbus , Andrea Cesalpino and Vesalius , before Harvey would provide a refined and complete description of

1230-457: A majority of respondents thought that being English was not dependent on race. 77% of white respondents in England agreed that "Being English is open to people of different ethnic backgrounds who identify as English", whereas 14% were of the view that "Only people who are white count as truly English". Amongst ethnic minority respondents, the equivalent figures were 68% and 19%. Research has found that

1353-781: A man called Foster who at one time was lodged in the debtor's prison over the gate. He eventually became Sir Stephen Foster , Lord Mayor of London . His widow, Agnes , renovated and extended Ludgate and the debtor's prison; the practice of making the debtors pay for their own food and lodging was also abolished. Her gift was commemorated by a brass wall plaque, which read: Devout souls that pass this way, For Stephen Foster, late mayor, heartily pray; And Dame Agnes , his spouse, to God consecrate, That of pity this house made, for Londoners in Ludgate; So that for lodging and water prisoners here nought pay, As their keepers shall answer at dreadful doomsday! In February 1554, Ludgate

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1476-597: A native British "North Atlantic" population and a Danish-like population. While much of the latter signature was attributed to the earlier settlement of the Anglo-Saxons, it was calculated that up to 6% of it could have come from Danish Vikings, with a further 4% contribution from a Norwegian-like source representing the Norwegian Vikings. The study also found an average 18% admixture from a source further south in Europe, which

1599-459: A notebook. At this time, at the age of thirty-seven, he was described as "a man of lowest stature, round faced; his eyes small, round, very black and full of spirit; his hair as black as a raven and curling". The notes which he used at the time are preserved in the British Museum . At the beginning of his lectures, Harvey laid down the canons for his guidance: Harvey continued to participate in

1722-402: A parliament being established. Krishan Kumar notes that support for measures to ensure that only English MPs can vote on legislation that applies only to England is generally higher than that for the establishment of an English parliament, although support for both varies depending on the timing of the opinion poll and the wording of the question. Electoral support for English nationalist parties

1845-417: A popular misconception, Harvey did not predict the existence of capillaries . His observations convinced him that direct connection between veins and arteries are unnecessary; he wrote "blood permeates the pores" in the flesh and it is "absorbed and imbibed from every part" by the veins. Harvey's discovery of the circulation of the blood was based on inference, not direct observation, and was incompatible with

1968-525: A relationship with Fabricius and read Fabricius's De Venarum Ostiolis . Harvey graduated as a Doctor of Medicine at the age of 24 from the University of Padua on 25 April 1602. Harvey had conducted himself so wonderfully well in the examination and had shown such skill, memory and learning that he had far surpassed even the great hopes which his examiners had formed of him. After graduating from Padua, Harvey immediately returned to England, where he obtained

2091-463: A rise in English self-awareness. This is linked to the expressions of national self-awareness of the other British nations of Wales, Scotland and, to some extent, Northern Ireland which take their most solid form in the new devolved political arrangements within the United Kingdom ;– and the waning of a shared British national identity with the growing distance between the end of

2214-627: A separate ethnic identity, others have assimilated and intermarried with the English. Since Oliver Cromwell 's resettlement of the Jews in 1656, there have been waves of Jewish immigration from Russia in the 19th century and from Germany in the 20th. After the French king Louis XIV declared Protestantism illegal in 1685 in the Edict of Fontainebleau , an estimated 50,000 Protestant Huguenots fled to England. Due to sustained and sometimes mass emigration of

2337-651: A separate people from the English. This separation was enshrined when Alfred the Great signed the Treaty of Alfred and Guthrum to establish the Danelaw, a division of England between English and Danish rule, with the Danes occupying northern and eastern England. However, Alfred's successors subsequently won military victories against the Danes, incorporating much of the Danelaw into the nascent kingdom of England. Danish invasions continued into

2460-509: A time be, as we have seen. I interpret it well that it will be a great motive for all here to have and procure assurance of settled peace . It is time to leave fighting when there is nothing to eat, nothing to be kept, and nothing to be gotten. Having returned to England in 1632. Harvey accompanied King Charles I wherever he went as ' Physician in Ordinary '. In particular, Charles's hunting expeditions gave Harvey access to many deer carcasses; it

2583-542: A veneer of Britishness. English people, like most Europeans, largely descend from three distinct lineages: Mesolithic hunter-gatherers , descended from a Cro-Magnon population that arrived in Europe about 45,000 years ago; Neolithic farmers who migrated from Anatolia during the Neolithic Revolution 9,000 years ago; and Yamnaya Steppe pastoralists who expanded into Europe from the Pontic–Caspian steppe in

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2706-458: A woman accused of being a witch. Initially, he told her that he was a wizard and had come to discuss the Craft with her, and asked whether she had a familiar . She put down a saucer of milk and called to a toad which came out and drank the milk. He then sent her out to fetch some ale, killed the toad and dissected it, concluding that it was a perfectly ordinary animal and not supernatural in any way. When

2829-495: Is a research facility focussing on biochemical pharmacology, orthopaedic diseases, endocrinology, genomics, clinical pharmacology and translational medicine and therapeutics. William Harvey Hospital in Ashford, Kent is named after him. Harvey's hometown of Folkestone, Kent also has a statue of him. English people Modern ethnicities The English people are an ethnic group and nation native to England , who speak

2952-464: Is also low, even though there is public support for many of the policies they espouse. The English Democrats gained just 64,826 votes in the 2010 UK general election , accounting for 0.3 per cent of all votes cast in England. Kumar argued in 2010 that "despite devolution and occasional bursts of English nationalism – more an expression of exasperation with the Scots or Northern Irish – the English remain on

3075-612: Is usually termed "elite dominance". The second process is explained through incentives, such as the Wergild outlined in the law code of Ine of Wessex which produced an incentive to become Anglo-Saxon or at least English speaking. Historian Malcolm Todd writes, "It is much more likely that a large proportion of the British population remained in place and was progressively dominated by a Germanic aristocracy, in some cases marrying into it and leaving Celtic names in the, admittedly very dubious, early lists of Anglo-Saxon dynasties. But how we identify

3198-590: The Anglo-Saxons , a group of closely related Germanic tribes that began migrating to eastern and southern Britain, from southern Denmark and northern Germany, in the 5th century AD, after the Romans had withdrawn from Britain . The Anglo-Saxons gave their name to England ("Engla land", meaning "Land of the Angles") and to the English. The Anglo-Saxons arrived in a land that was already populated by people commonly referred to as

3321-544: The British Empire and the present. Many recent immigrants to England have assumed a solely British identity, while others have developed dual or mixed identities. Use of the word "English" to describe Britons from ethnic minorities in England is complicated by most non-white people in England identifying as British rather than English. In their 2004 Annual Population Survey , the Office for National Statistics compared

3444-584: The English language , a West Germanic language, and share a common ancestry, history, and culture. The English identity began with the Anglo-Saxons , when they were known as the Angelcynn , meaning race or tribe of the Angles . Their ethnonym is derived from the Angles, one of the Germanic peoples who invaded Britain around the 5th century AD. The English largely descend from two main historical population groups:

3567-626: The Irish , current estimates indicate that around 6 million people in the UK have at least one grandparent born in the Republic of Ireland. There has been a small black presence in England since the 16th century due to the slave trade , and a small Indian presence since at least the 17th century because of the East India Company and British Raj . Black and Asian populations have only grown throughout

3690-582: The Old English term "hlid-geat" a common Old English compound meaning "postern" or "swing gate". Ludgate is believed to have been one of four original gates in the Roman London Wall , work on which started in 190 AD. Anti-royalist forces rebuilt the gate during the First Barons' War (1215–17) using materials recovered from the destroyed houses of Jews . The gate was rebuilt about 1450 by

3813-641: The Royal College of Physicians . He used it to point to objects during his lectures. Several medical buildings and institutions are named after or otherwise commemorate Harvey. The Harveian Society of Edinburgh was founded in 1782 by Dr Andrew Duncan . The Society holds an annual Festival in honour of Harvey where the President of the Society delivers the Harveian Oration, followed by a formal dinner. The venue for

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3936-606: The Treaty of Union . The Parliament of Scotland had previously passed its own Act of Union, so the Kingdom of Great Britain was born on 1 May 1707. In 1801, another Act of Union formed a union between the Kingdom of Great Britain and the Kingdom of Ireland , creating the United Kingdom of Great Britain and Ireland . In 1922, about two-thirds of the Irish population (those who lived in 26 of

4059-706: The devolution in the late 1990s of some powers to the Scottish Parliament and National Assembly for Wales . In policy areas for which the devolved administrations in Scotland, Wales and Northern Ireland have responsibility, the UK Parliament votes on laws that consequently only apply to England. Because the Westminster Parliament is composed of MPs from throughout the United Kingdom, this has given rise to

4182-426: The pulmonary artery . Whilst doing this, the physician reiterates the fact that these two ventricles move together almost simultaneously and not independently as had been thought previously by his predecessors. This discovery was made while observing the heart of such animals as the eel and several other types of fish; indeed, the general study of countless animals was of utmost importance to Harvey's research: among

4305-464: The " Romano-British "—the descendants of the native Brittonic-speaking population that lived in the area of Britain under Roman rule during the 1st–5th centuries AD. The multi-ethnic nature of the Roman Empire meant that small numbers of other peoples may have also been present in England before the Anglo-Saxons arrived. There is archaeological evidence, for example, of an early North African presence in

4428-462: The " West Lothian question ", a reference to the situation in which MPs representing constituencies outside England can vote on matters affecting only England, but MPs cannot vote on the same matters in relation to the other parts of the UK. Consequently, groups such as the CEP have called for the creation of a devolved English Parliament , claiming that there is now a discriminatory democratic deficit against

4551-478: The 'working world' were made, however; here is an excerpt of one of Harvey's answers: Would you be the man who should recommend me to quit the peaceful haven where I now pass my life and launch again upon the faithless sea? You know full well what a storm my former lucubrations raised. Much better is it oftentimes to grow wise at home and in private, than by publishing what you have amassed with infinite labour, to stir up tempests that may rob you of peace and quiet for

4674-552: The 11th century, and there were both English and Danish kings in the period following the unification of England (for example, Æthelred II (978–1013 and 1014–1016) was English but Cnut (1016–1035) was Danish). Gradually, the Danes in England came to be seen as 'English'. They had a noticeable impact on the English language: many English words, such as anger , ball , egg , got , knife , take , and they , are of Old Norse origin , and place names that end in -thwaite and -by are Scandinavian in origin. The English population

4797-463: The 17th century, William Harvey had already discerned the existence of the Ductus arteriosus and explained its relative function. Here he says, "...in embryos , whilst the lungs are in a state of inaction, performing no function, subject to no movement any more than if they had not been present, Nature uses the two ventricles of the heart as if they formed but one for the transmission of the blood." However,

4920-507: The 17th century, two separate systems were thought to be involved in blood circulation: the natural system, containing venous blood which had its origin in the liver, and the vital system, containing arterial blood and the 'spirits' which flowed from the heart, distributing heat and life to all parts. Like bellows , it was thought the lungs fanned and cooled this vital blood. Independently of Ibn Al-Nafis, Michael Servetus identified pulmonary circulation, but this discovery did not reach

5043-540: The 32 counties of Ireland), left the United Kingdom to form the Irish Free State . The remainder became the United Kingdom of Great Britain and Northern Ireland, although this name was not introduced until 1927, after some years in which the term "United Kingdom" had been little used. Throughout the history of the UK, the English have been dominant in population and in political weight. As a consequence, notions of 'Englishness' and 'Britishness' are often very similar. At

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5166-456: The 72-page Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus contains the mature account of the circulation of the blood . Opening with a dedication to King Charles I, the quarto has 17 chapters which give a clear and connected account of the action of the heart and the consequent movement of the blood around the body in a circuit. Having only a tiny lens at his disposal, Harvey

5289-522: The Anglo-Saxon period on the other. Samples from modern-day Wales were found to be similar to those from the Iron Age and Roman burials, while samples from much of modern England, East Anglia in particular, were closer to the Anglo-Saxon-era burial. This was found to demonstrate a "profound impact" from the Anglo-Saxon migrations on the modern English gene pool, though no specific percentages were given in

5412-466: The English language became more important even in the court, and the Normans were gradually assimilated, until, by the 14th century, both rulers and subjects regarded themselves as English and spoke the English language. Despite the assimilation of the Normans, the distinction between 'English' and 'French' people survived in some official documents long after it had fallen out of common use, in particular in

5535-578: The English. The establishment of an English parliament has also been backed by a number of Scottish and Welsh nationalists. Writer Paul Johnson has suggested that like most dominant groups, the English have only demonstrated interest in their ethnic self-definition when they were feeling oppressed. John Curtice argues that "In the early years of devolution...there was little sign" of an English backlash against devolution for Scotland and Wales, but that more recently survey data shows tentative signs of "a form of English nationalism...beginning to emerge among

5658-670: The Festival alternates between the Royal College of Physicians of Edinburgh and the Royal College of Surgeons of Edinburgh . The Harveian Society of London is a medical society founded in 1831 based in The Medical Society of London, Chandos Street, in Cavendish Square. The Royal College of Physicians of London holds an annual lecture established by William Harvey in 1656 called the Harveian Oration . The Harvey Club of London

5781-804: The Iberian Bell Beakers, but appeared to be an offshoot of the Corded Ware single grave people, as developed in Western Europe. It is currently unknown whether these Beaker peoples went on to develop Celtic languages in the British Isles , or whether later Celtic migrations introduced Celtic languages to Britain. The close genetic affinity of these Beaker people to Continental North Europeans means that British and Irish populations cluster genetically very closely with other Northwest European populations, regardless of how much Anglo-Saxon and Viking ancestry

5904-500: The Lumleian lectures while also taking care of his patients at St Bartholomew's Hospital ; he thus soon attained an important and fairly lucrative practice, which climaxed with his appointment as 'Physician Extraordinary' to King James I on 3 February 1618. He seems to have similarly served various aristocrats , including Lord Chancellor Bacon . Bacon entirely failed to impress the more practical-minded Harvey, who refused to regard him as

6027-519: The Norman-Welsh cleric Geoffrey of Monmouth , Ludgate was named after the ancient British king Lud . Lud was said to be the brother of King Cassivelaunus but some folklorists think he is a manifestation of the god Nodens . There are other suggestions for the origins of the name, although none has been universally accepted. Later writers said it was derived from "flood gate" or "Fleet gate", from "ludgeat", meaning "back gate" or " postern ", or from

6150-608: The UK generally, as immigration from the British Empire and the subsequent Commonwealth of Nations was encouraged due to labour shortages during post World War II rebuilding. However, these groups are often still considered to be ethnic minorities and research has shown that black and Asian people in the UK are more likely to identify as British rather than with one of the state's four constituent nations, including England. A nationally representative survey published in June 2021 found that

6273-511: The UK, it is also "problematic for the English [...] when it comes to conceiving of their national identity. It tells of the difficulty that most English people have of distinguishing themselves, in a collective way, from the other inhabitants of the British Isles". In 1965, the historian A. J. P. Taylor wrote, When the Oxford History of England was launched a generation ago, "England"

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6396-415: The UK. In his study of English identity, Krishan Kumar describes a common slip of the tongue in which people say "English, I mean British". He notes that this slip is normally made only by the English themselves and by foreigners: "Non-English members of the United Kingdom rarely say 'British' when they mean 'English ' ". Kumar suggests that although this blurring is a sign of England's dominant position with

6519-539: The United Kingdom . The majority of people living in England are British citizens. In the Acts of Union 1707 , the Kingdom of England and the Kingdom of Scotland merged to become the Kingdom of Great Britain . Over the years, English customs and identity have become fairly closely aligned with British customs and identity in general. The demonyms for men and women from England are Englishman and Englishwoman. England itself has no devolved government. The 1990s witnessed

6642-575: The United Kingdom. Wales was annexed by England by the Laws in Wales Acts 1535–1542 , which incorporated Wales into the English state. A new British identity was subsequently developed when James VI of Scotland became James I of England as well, and expressed the desire to be known as the monarch of Britain. In 1707, England formed a union with Scotland by passing an Act of Union in March 1707 that ratified

6765-583: The United States, Canada, Australia, South Africa and New Zealand. In the 2020 United States census , English Americans were the largest group in the United States with 46.5 million Americans self-identifying as having some English origins (many combined with another heritage) representing (19.8%) of the White American population. This includes 25.5 million (12.5%) who were "English alone" - one origin. However, demographers regard this as an undercount, as

6888-556: The West Germanic tribes, including the Angles, Saxons , and Jutes who settled in Southern Britain following the withdrawal of the Romans , and the partially Romanised Celtic Britons who already lived there. Collectively known as the Anglo-Saxons , they founded what was to become the Kingdom of England by the 10th century, in response to the invasion and extensive settlement of Danes and other Norsemen that began in

7011-413: The apex of Harvey's work is probably the eighth chapter, in which he deals with the actual quantity of blood passing through the heart from the veins to the arteries. Coming into conflict with Galen 's accepted view of the liver as the origin of venous blood, Harvey estimated the capacity of the heart, how much blood is expelled through each pump of the heart, and the number of times the heart beats in

7134-552: The apothecary. And you shall take no gift or reward... for your counsel... This you will promise to do as you shall answer before God... " Harvey earned around thirty-three pounds a year and lived in a small house in Ludgate , although two houses in West Smithfield were attached as fringe benefits to the post of Physician. At this point, the physician's function consisted of a simple but thorough analysis of patients who were brought to

7257-417: The arrival of the Anglo-Saxons and their relationship with the Romano-British is a matter of debate. The traditional view is that a mass invasion by various Anglo-Saxon tribes largely displaced the indigenous British population in southern and eastern Britain (modern-day England with the exception of Cornwall ). This is supported by the writings of Gildas , who gives the only contemporary historical account of

7380-430: The arteries to come into the arm, since arteries are deeper in the flesh than the veins. When this was done, the opposite effect was seen in the lower arm. It was now warm and swollen. The veins were also more visible since now they were full of blood. Harvey then noticed little bumps in the veins, which he realised were the valves of the veins discovered by his teacher, Hieronymus Fabricius . Harvey tried to push blood in

7503-410: The best of your knowledge in the profession of physic to the poor then present, or any other of the poor at any time of the week which shall be sent home unto you by the Hospitaller... You shall not, for favor, lucre or gain, appoint or write anything for the poor but such good and wholesome things as you shall think with your best advice will do the poor good, without any affection or respect to be had to

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7626-416: The cases of eastern regions such as East Anglia and Lincolnshire, while in parts of Northumbria, much of the native population likely remained in place as the incomers took over as elites. In a study of place names in northeastern England and southern Scotland, Bethany Fox found that the migrants settled in large numbers in river valleys, such as those of the Tyne and the Tweed, with the Britons moving to

7749-464: The central panel of a wall of the dining room at Rolls Park, Chigwell , in Essex . William was the eldest of nine children, seven sons and two daughters, of Thomas and his wife Joan Halke. Notable family connections include Heneage Finch, 1st Earl of Nottingham , who married William's niece Elizabeth Harvey, and the diplomat Sir Daniel Harvey . His great nephew was the naval hero Eliab Harvey , captain of HMS Temeraire . Harvey's initial education

7872-415: The circulatory system. Harvey's other major work was Exercitationes de generatione animalium ( On Animal Generation ), published in 1651. He had been working on it for many years but might never have finished it without the encouragement of his friend George Ent . The book starts with a description of the development of the hen's egg. The major part is theoretical, dealing with Aristotle 's theories and

7995-472: The complex nature of national identities, with many people considering themselves both English and British. A 2017 survey by YouGov found that 38% of English voters considered themselves both English and British, alongside 19% who felt English but not British. Recent surveys of public opinion on the establishment of an English parliament have given widely varying conclusions. In the first five years of devolution for Scotland and Wales, support in England for

8118-420: The context of Indo-European migrations 5,000 years ago. Recent genetic studies have suggested that Britain's Neolithic population was largely replaced by a population from North Continental Europe characterised by the Bell Beaker culture around 2400 BC, associated with the Yamnaya people from the Pontic-Caspian Steppe . This population lacked genetic affinity to some other Bell Beaker populations, such as

8241-522: The countries of France and Spain during the Mantuan War and Plague . During this journey he wrote to Viscount Dorchester : I can complain that by the way we could scarce see a dog, crow, kite, raven or any other bird, or anything to anatomize, only some few miserable people, the relics of the war and the plague where famine had made anatomies before I came. It is scarce credible in so rich, populous, and plentiful countries as these were that so much misery and desolation, poverty and famine should in so short

8364-409: The dead palsy in his tongue; then he saw what was to become of him. He knew there were then no hopes of his recovery, so presently he sends for his young nephews to come up to him. He then made signs (for seized with the dead palsy in his tongue he could not speak) to let him blood his tongue, which did him little or no good, and so ended his days, dying in the evening of the day on which he was stricken,

8487-443: The death of King Stephen in 1154, when the succession passed to Henry II , House of Plantagenet (based in France), and England became part of the Angevin Empire until its collapse in 1214. Anglo-Norman and Latin continued to be the two languages used officially by the Plantagenet kings until Edward I came to the throne, when Middle English became used in official documents, but alongside Anglo-Norman and Latin. Over time

8610-424: The degree of Doctor of Medicine from the University of Cambridge that same year, and became a fellow of Gonville and Caius College, Cambridge . Following this, Harvey established himself in London, joining the Royal College of Physicians on 5 October 1604. A few weeks after his admission, Harvey married Elizabeth Browne, "daughter of Lancelot Browne Dr. Physic" (a medical doctor). They had no children. Harvey

8733-468: The die is cast, and my trust is in my love of truth, and the candour that inheres in cultivated minds. Harvey's premonitions that his discovery would be met with scepticism, derision, and abuse, were entirely justified. It took twenty years for his theory of the circulation of the blood to be generally accepted. At the time of Harvey's publication, Galen had been an influential medical authority for several centuries. Galen believed that blood passed between

8856-595: The establishment of an English parliament was low at between 16 and 19%, according to successive British Social Attitudes Surveys . A report, also based on the British Social Attitudes Survey, published in December 2010 suggests that only 29% of people in England support the establishment of an English parliament, though this figure had risen from 17% in 2007. One 2007 poll carried out for BBC Newsnight , however, found that 61 per cent would support such

8979-416: The ethnic identities of British people with their perceived national identity . They found that while 58% of white people in England described their nationality as "English", non-white people were more likely to describe themselves as "British". It is unclear how many British people consider themselves English. The words "English" and "British" are often incorrectly used interchangeably, especially outside

9102-433: The first time in 1613 and the second time in 1625. Eventually, Harvey was also elected Treasurer of the College. Harvey was a prominent sceptic regarding allegations of witchcraft. He was one of the examiners of four women from Lancashire accused of witchcraft in 1634, and as a consequence of his report, all of them were acquitted. Earlier, in 1632, while travelling with the King to Newmarket , he had been sent to investigate

9225-449: The general public". Michael Kenny, Richard English and Richard Hayton, meanwhile, argue that the resurgence in English nationalism predates devolution, being observable in the early 1990s, but that this resurgence does not necessarily have negative implications for the perception of the UK as a political union. Others question whether devolution has led to a rise in English national identity at all, arguing that survey data fails to portray

9348-435: The heart every time it pumped. The next estimate he used was that the heart beats 1,000 times every half an hour, which gave 10 pounds 6 ounces of blood in a half an hour, and when this number was multiplied by 48 half hours in a day he realised that the liver would have to produce 498 pounds of blood in a day, more than the weight of the whole body. Having this simple but essential mathematical proportion at hand – which proved

9471-401: The heart to the lungs, where it mixed with air, and then back to the heart, from which it spread to the rest of the body. Harvey's discoveries inevitably and historically came into conflict with Galen's teachings and the publication of his treatise De Motu Cordis incited considerable controversy within the medical community. Some doctors affirmed they would "rather err with Galen than proclaim

9594-412: The heart when it was active in order to truly comprehend its true movement; a task which even he found of great difficulty, as he says: ...I found the task so truly arduous... that I was almost tempted to think... that the movement of the heart was only to be comprehended by God. For I could neither rightly perceive at first when the systole and when the diastole took place by reason of the rapidity of

9717-578: The hospital once a week and the subsequent writing of prescriptions. The next important phase of Harvey's life began with his appointment to the office of Lumleian lecturer on 4 August 1615. The Lumleian lectureship, founded by Lord Lumley and Dr. Richard Caldwell in 1582, consisted in giving lectures for a period of seven years, with the purpose of "spreading light" and increasing the general knowledge of anatomy throughout England. Harvey began his lectures in April 1616, and also compiled his lecture notes in

9840-515: The index of inconsistency is high, and many, if not most, people from English stock have a tendency (since the introduction of a new 'American' category and ignoring the ancestry question in the 2000 census) to identify as simply Americans or if of mixed European ancestry, identify with a more recent and differentiated ethnic group. Prior to this, in the 2000 census , 24,509,692 Americans described their ancestry as wholly or partly English. In addition, 1,035,133 recorded British ancestry. This

9963-472: The late 9th century. This was followed by the Norman Conquest and limited settlement of Normans in England in the late 11th century and a sizeable number of French Protestants who emigrated between the 16th and 18th centuries. Some definitions of English people include, while others exclude, people descended from later migration into England. England is the largest and most populous country of

10086-400: The legal process Presentment of Englishry (a rule by which a hundred had to prove an unidentified murdered body found on their soil to be that of an Englishman, rather than a Norman, if they wanted to avoid a fine). This law was abolished in 1340. Since the 18th century, England has been one part of a wider political entity covering all or part of the British Isles, which today is called

10209-477: The less fertile hill country and becoming acculturated over a longer period. Fox describes the process by which English came to dominate this region as "a synthesis of mass-migration and elite-takeover models." From about 800 AD, waves of Danish Viking assaults on the coastlines of the British Isles were gradually followed by a succession of Danish settlers in England. At first, the Vikings were very much considered

10332-402: The movement... This initial thought led Harvey's ambition and assiduousness to a detailed analysis of the overall structure of the heart (studied with fewer hindrances in cold-blooded animals). After this, Harvey analyses the arteries , showing how their pulsation depends upon the contraction of the left ventricle , while the contraction of the right ventricle propels its charge of blood into

10455-553: The new French-speaking Norman elite almost universally replaced the Anglo-Saxon aristocracy and church leaders. After the conquest, "English" normally included all natives of England, whether they were of Anglo-Saxon, Scandinavian or Celtic ancestry, to distinguish them from the Norman invaders, who were regarded as "Norman" even if born in England, for a generation or two after the Conquest. The Norman dynasty ruled England for 87 years until

10578-443: The ones already cited, one can add the study of the snail , the invisible shrimp , the chick before its hatching and even the pigeon. A digression to an experiment can be made to this note: using the inactive heart of a dead pigeon and placing upon it a finger wet with saliva , Harvey was able to witness a transitory and yet incontrovertible pulsation. He had just witnessed the heart's ability to recover from fatigue . As early as

10701-417: The organ would swell up. This process was later performed on the human body (in the image on the right): the physician tied a tight ligature onto the upper arm of a person. This would cut off blood flow from the arteries and the veins. When this was done, the arm below the ligature was cool and pale, while above the ligature it was warm and swollen. The ligature was loosened slightly, which allowed blood from

10824-402: The overall impossible aforementioned role of the liver – Harvey went on to prove how the blood circulated in a circle by means of countless experiments initially done on serpents and fish: tying their veins and arteries in separate periods of time, Harvey noticed the modifications which occurred; indeed, as he tied the veins, the heart would become empty, while as he did the same to the arteries,

10947-554: The palsy giving him an easy passport. His will distributed his material goods and wealth throughout his extended family and also left a substantial amount of money to the Royal College of Physicians . Harvey was buried in St. Andrew's Church in Hempstead in northern Essex . The funeral procession started on 26 June 1657, leading Harvey to be placed in the 'Harvey Chapel' built by Eliab. The conditions of Harvey's burial are also known: "Harvey

11070-413: The period, and describes the slaughter and starvation of native Britons by invading tribes ( aduentus Saxonum ). Furthermore, the English language contains no more than a handful of words borrowed from Brittonic sources. This view was later re-evaluated by some archaeologists and historians, with a more small-scale migration being posited, possibly based around an elite of male warriors that took over

11193-849: The physician was made "Doctor of Physic" in 1642 and later Warden of Merton College in 1645. "In Oxford he (Harvey) very soon settled down to his accustomed pursuits, unmindful of the clatter of arms and of the constant marching and countermarching around him, for the city remained the base of operations until its surrender... " The surrender of Oxford in 1645 marks the beginning of Harvey's gradual retirement from public life and duties. Now sixty-eight years old and childless, Harvey had lost three brothers and his wife by this time. He thus decided to return to London, and lived with his brothers Eliab and Daniel at different periods. Having retired from St Bartholomew's Hospital and his various other aforementioned positions, he passed most of this time reading general literature. Several attempts to bring Harvey back into

11316-714: The population of Northern Ireland and 20% of the Welsh population were born in England. Similarly, the census of the Republic of Ireland does not collect information on ethnicity, but it does record that there are over 200,000 people living in Ireland who were born in England and Wales . English ethnic descent and emigrant communities are found primarily in the Western world , and settled in significant numbers in some areas. Substantial populations descended from English colonists and immigrants exist in

11439-619: The prevailing paradigm at the time. That paradigm held, among other things, that the blood could flow from one side of the heart to the other. Harvey knew that he was facing an uphill battle: But what remains to be said about the quantity and source of the blood which thus passes, is of so novel and unheard-of character that I not only fear injury to myself from the envy of a few, but I tremble lest I have mankind at large for my enemies, so much doth want and custom, that become as another nature, and doctrine once sown and that hath struck deep root, and respect for antiquity, influence all men : still

11562-459: The proportion of people who consider being white to be a necessary component of Englishness has declined over time. The 1990s witnessed a resurgence of English national identity. Survey data shows a rise in the number of people in England describing their national identity as English and a fall in the number describing themselves as British. Today, black and minority ethnic people of England still generally identify as British rather than English to

11685-524: The public because it was written down for the first time in the Manuscript of Paris in 1546. It was later published in the theological work which caused his execution in 1553, almost all copies of which were destroyed. In: Christianismi Restitutio , Book V, the Aragonese Miguel Servet (Michel de Villeneuve, 1509?–1553) wrote: 'The blood is passed through the pulmonary artery to the pulmonary vein for

11808-707: The reign of King Edward VI . The gateway was finally demolished in 1760 at the request of the local citizens. It was still in use as a debtor's prison, so the inmates were transferred to the City workhouse in Bishopsgate . The statues from the facade were preserved at the Church of St Dunstan-in-the-West in Fleet Street . When the church was rebuilt in 1831, they were sold and taken to Hertford Villa in Regent's Park , but were returned to

11931-498: The rest of your days. Harvey died at Roehampton in the house of his brother Eliab on 3 June 1657. Descriptions of the event seem to show that he died of a cerebral haemorrhage from vessels long injured by gout : it is highly probable that the left middle cerebral artery malfunctioned, leading to a gradual accumulation of blood in the brain which eventually overwhelmed it. There exists a fairly detailed account of what happened on that day. Harvey went to speak and found that he had

12054-500: The rule of the country and gradually acculturated the people living there. Within this theory, two processes leading to Anglo-Saxonisation have been proposed. One is similar to culture changes observed in Russia, North Africa and parts of the Islamic world, where a politically and socially powerful minority culture becomes, over a rather short period, adopted by a settled majority. This process

12177-485: The same time, after the Union of 1707, the English, along with the other peoples of the British Isles, have been encouraged to think of themselves as British rather than to identify themselves with the constituent nations. England has been the destination of varied numbers of migrants at different periods from the 17th century onwards. While some members of these groups seek to practise a form of pluralism, attempting to maintain

12300-567: The study. A third study combined the ancient data from both of the preceding studies and compared it to a large number of modern samples from across Britain and Ireland. This study found that modern southern, central and eastern English populations were of "a predominantly Anglo-Saxon-like ancestry" while those from northern and southwestern England had a greater degree of indigenous origin. A major 2020 study, which used DNA from Viking-era burials in various regions across Europe, found that modern English samples showed nearly equal contributions from

12423-598: The surviving Britons in areas of predominantly Anglo-Saxon settlement, either archaeologically or linguistically, is still one of the deepest problems of early English history." An emerging view is that the degree of population replacement by the Anglo-Saxons, and thus the degree of survival of the Romano-Britons, varied across England, and that as such the overall settlement of Britain by the Anglo-Saxons cannot be described by any one process in particular. Large-scale migration and population shift seems to be most applicable in

12546-423: The truth with Harvey." Galen incompletely perceived the function of the heart, believing it a "productor of heat", while the function of its affluents, the arteries , was that of cooling the blood as the lungs "...fanned and cooled the heart itself". Galen thought that during dilation the arteries sucked in air, while during their contraction they discharged vapours through pores in the flesh and skin. Until

12669-415: The vein down the arm, but to no avail. When he tried to push it up the arm, it moved quite easily. The same effect was seen in other veins of the body, except the veins in the neck. Those veins were different from the others – they did not allow blood to flow up, but only down. This led Harvey to believe that the veins allowed blood to flow to the heart, and the valves maintained the one-way flow. Contrary to

12792-481: The ventricles by means of invisible pores. According to Galen's views, the venous system was quite separate from the arterial system, except when they came in contact through the unseen pores. Arabic scholar Ibn al-Nafis had disputed aspects of Galen's views, providing a model that seems to imply a form of pulmonary circulation in his Commentary on Anatomy in Avicenna 's Canon (1242). Al-Nafis stated that blood moved from

12915-433: The whole satisfied with current constitutional arrangements". From the earliest times, English people have left England to settle in other parts of Great Britain and Northern Ireland. It is impossible to identify their numbers, as British censuses have historically not invited respondents to identify themselves as English. However, the census does record place of birth, revealing that 8.1% of Scotland's population, 3.7% of

13038-495: The woman returned she was naturally very angry and upset, but Harvey eventually silenced her by stating that he was the King's Physician, sent to discover whether she was a witch, and if she were, to have her apprehended. At the age of fifty-two, Harvey received commands from the king to accompany the Duke of Lennox during his trip abroad. This voyage – the first after Harvey's return from Padua – lasted three years, taking Harvey through

13161-409: The work of the physicians following Galen and up to Fabricius. Finally, he deals with embryogenesis in viviparous animals, especially hinds and does. The treatment is generally Aristotelian and limited by use of a simple magnifying lens. Needham claims the following achievements for this work. Harvey's whalebone demonstration rod, tipped with silver, resides in the silver room of the museum of

13284-440: Was a jurat of Folkestone where he served as mayor in 1600. Records and personal descriptions delineate him as an overall calm, diligent, and intelligent man whose sons “... revered, consulted and implicitly trusted in him...” (they) made their father the treasurer of their wealth when they acquired great estates...(He) kept, employed, and improved their gainings to their great advantage." Thomas Harvey's portrait can still be seen in

13407-558: Was a munificent Benefactor did in the years 1882–1883, by permission of the Representatives of the Harvey family, undertake this duty. In accordance with this determination the leaden mortuary chest containing the remains of Harvey was repaired, and was, as far as possible, restored to its original state... Published in 1628 in the city of Frankfurt (host to an annual book fair that Harvey knew would allow immediate dispersion of his work),

13530-605: Was a numerical decrease from the census in 1990 where 32,651,788 people or 13.1% of the population self-identified with English ancestry. Ludgate Ludgate was the westernmost gate in London Wall . Of Roman origin, it was rebuilt several times and finally demolished on 30th July 1760. The name survives in Ludgate Hill , an eastward continuation of Fleet Street , Ludgate Circus and Ludgate Square. The gates' materials were sold for 148£. According to legend, recorded by

13653-614: Was carried out in Folkestone, where he learned Latin . He then entered the King's School ( Canterbury ). Harvey stayed at the King's School for five years, after which he matriculated at Gonville and Caius College, Cambridge in 1593. Harvey graduated as a Bachelor of Arts from Caius in 1597. He then travelled through France and Germany to Italy, where he entered the University of Padua , in 1599. During Harvey's years of study there, he developed

13776-636: Was elected a Fellow of the Royal College of Physicians on 5 June 1607, which earned him the Post-nominal letters FRCP. He then accepted a position at St Bartholomew's Hospital that he was to occupy for almost all the rest of his life. Succeeding Dr Wilkinson on 14 October 1609, he became the Physician in charge at St Bartholomew's Hospital , which enjoined him, "in God's most holy name" to "endeavor yourself to do

13899-590: Was for the most part a politically unified entity, and remained permanently so after 954. The nation of England was formed in 12 July 927 by Æthelstan of Wessex after the Treaty of Eamont Bridge , as Wessex grew from a relatively small kingdom in the South West to become the founder of the Kingdom of the English, incorporating all Anglo-Saxon kingdoms and the Danelaw. The Norman conquest of England during 1066 brought Anglo-Saxon and Danish rule of England to an end, as

14022-624: Was founded in Canada in 1919 and is based in the University of Western Ontario . The Harvey Society , found in 1905, is based in New York City and hosts an annual lecture series on recent advances in biomedical sciences. The main lecture theatre of the School of Clinical Medicine, University of Cambridge is named after William Harvey, who was an alumnus of the institute. William Harvey Research Institute at Barts and The London School of Medicine and Dentistry

14145-433: Was interpreted as reflecting the legacy of French migration under the Normans. A landmark 2022 study titled "The Anglo-Saxon migration and the formation of the early English gene pool", found the English to be of plurality Anglo-Saxon-like ancestry, with heavy native Celtic Briton , and newly confirmed medieval French admixture. Significant regional variation was also observed. The first people to be called "English" were

14268-738: Was introduced during the 1st millennium. The influence of later invasions and migrations on the English population has been debated, as studies that sampled only modern DNA have produced uncertain results and have thus been subject to a large variety of interpretations. More recently, however, ancient DNA has been used to provide a clearer picture of the genetic effects of these movements of people. One 2016 study, using Iron Age and Anglo-Saxon era DNA found at grave sites in Cambridgeshire, calculated that ten modern day eastern English samples had 38% Anglo-Saxon ancestry on average, while ten Welsh and Scottish samples each had 30% Anglo-Saxon ancestry, with

14391-450: Was laid in the chapel between the bodies of his two nieces, and like them he was lapt in lead, coffin less". On St. Luke's Day , 18 October 1883, Harvey's remains were reinterred, the leaden case carried from the vault by eight Fellows of the College of Physicians , and deposited in a sarcophagus containing his works and an inscription: The body of William Harvey lapt in lead, simply soldered,

14514-510: Was laid without shell or enclosure of any kind in the Harvey vault of this Church of Hempstead , Essex, in June 1657. In the course of time the lead enclosing the remains was, from expose and natural decay, so seriously damaged as to endanger its preservation, rendering some repair of it the duty of those interested in the memory of the illustrious discoverer of the circulation of the Blood. The Royal College of Physicians , of which corporate body Harvey

14637-420: Was not able to reach the adequate pictures that were attained through such microscopes used by Antonie van Leeuwenhoek ; thus he had to resort to theory – and not practical evidence – in certain parts of his book. After the first chapter, which simply outlines past ideas and accepted rules regarding the heart and lungs, Harvey moves on to a fundamental premise to his treatise, stating that it was important to study

14760-405: Was not politically unified until the 10th century. Before then, there were a number of petty kingdoms which gradually coalesced into a heptarchy of seven states, the most powerful of which were Mercia and Wessex . The English nation state began to form when the Anglo-Saxon kingdoms united against Danish Viking invasions, which began around 800 AD. Over the following century and a half England

14883-407: Was still an all-embracing word. It meant indiscriminately England and Wales; Great Britain; the United Kingdom; and even the British Empire. Foreigners used it as the name of a Great Power and indeed continue to do so. Bonar Law , by origin a Scotch Canadian , was not ashamed to describe himself as "Prime Minister of England" [...] Now terms have become more rigorous. The use of "England" except for

15006-624: Was the final setting of Wyatt's rebellion , when Sir Thomas Wyatt the Younger arrived at the gate with part of his army numbering three or four hundred men. The gate was defended by Lord William Howard with the local militia , who refused entry to the rebels, causing them to retreat and later surrender. Ludgate was rebuilt in 1586 to the design of William Kerwin; niches in the facade were furnished with statues of Queen Elizabeth I and King Lud with his two sons; these statues replaced medieval ones that had been defaced by Protestant iconoclasts during

15129-697: Was upon them that Harvey made many observations and developed his theories. Harvey returned to Italy in October 1636, dining at the English College, Rome, as a guest of the Jesuits there. It is possible he met Galileo in Florence en route. During the English Civil War a mob of citizen-soldiers opposed to the King entered Harvey's lodgings, stole his goods, and scattered his papers. The papers consisted of "the records of

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