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National TB Elimination Program (India)

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147-667: The National Tuberculosis Elimination Programme (NTEP), earlier known as the Revised National Tuberculosis Control Programme (RNTCP) , is the Public Health initiative of the Government of India that organizes its anti-Tuberculosis efforts. It functions as a flagship component of the National Health Mission (NHM) and provides technical and managerial leadership to anti-tuberculosis activities in

294-460: A basic level of medical care and disease prevention. A major public health concern in developing countries is poor maternal and child health , exacerbated by malnutrition and poverty coupled with governments' reluctance in implementing public health policies. Developed nations are at greater risk of certain public health crises, including childhood obesity, although overweight populations in low- and middle-income countries are catching up. From

441-613: A basic level of medical care and disease prevention. As a result, a large majority of disease and mortality in developing countries results from and contributes to extreme poverty . For example, many African governments spend less than $ 100 USD per person per year on health care, while, in the United States, the federal government spent approximately $ 10,600 USD per capita in 2019. However, expenditures on health care should not be confused with spending on public health. Public health measures may not generally be considered "health care" in

588-410: A component of preventive medicine and public health. It is implemented as part of primary care rather than a specialty in its own right. Valles argues that the term social medicine has a narrower and more biomedical focus than the term population health. The purpose of a public health intervention is to prevent and mitigate diseases, injuries , and other health conditions. The overall goal

735-441: A country's overall health care system. Many interventions of public health interest are delivered outside of health facilities , such as food safety surveillance, distribution of condoms and needle-exchange programs for the prevention of transmissible diseases. Public health requires Geographic Information Systems (GIS) because risk, vulnerability and exposure involve geographic aspects. A dilemma in public health ethics

882-628: A defense against drugs used to treat them, or certain strains of microbes that have a natural resistance to antimicrobials becoming much more prevalent than the ones that are easily defeated with medication. While antimicrobial resistance does occur naturally over time, the use of antimicrobial agents in a variety of settings both within the healthcare industry and outside of has led to antimicrobial resistance becoming increasingly more prevalent. Although many microbes develop resistance to antibiotics over time though natural mutation, overprescribing and inappropriate prescription of antibiotics have accelerated

1029-663: A form of "health fascism" by a number of scholars, objectifying the individual with no considerations of emotional or social factors. When public health initiatives began to emerge in England in modern times (18th century onwards) there were three core strands of public health which were all related to statecraft: Supply of clean water and sanitation (for example London sewerage system ); control of infectious diseases (including vaccination and quarantine ); an evolving infrastructure of various sciences, e.g. statistics, microbiology, epidemiology, sciences of engineering. Great Britain

1176-488: A handful of people or as large as a village or an entire city. The concept of health takes into account physical, psychological , and social well-being . As such, according to the World Health Organization , "health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity". Public health is related to global health which is the health of populations in

1323-503: A higher yield of crops has resulted in many of these microbes evolving a tolerance against these antimicrobial agents. Currently there are over 4000 antimicrobial pesticides registered with the US Environmental Protection Agency (EPA) and sold to market, showing the widespread use of these agents. It is estimated that for every single meal a person consumes, 0.3 g of pesticides is used, as 90% of all pesticide use

1470-408: A limited amount of time or money to see a doctor. This increased access makes it extremely easy to obtain antimicrobials. An example is India, where in the state of Punjab 73% of the population resorted to treating their minor health issues and chronic illnesses through self-medication. Self-medication is higher outside the hospital environment, and this is linked to higher use of antibiotics, with

1617-611: A major threat to public health." Each year, nearly 5 million deaths are associated with AMR globally. In 2019, global deaths attributable to AMR numbered 1.27 million in 2019. That same year, AMR may have contributed to 5 million deaths and one in five people who died due to AMR were children under five years old. In 2018, WHO considered antibiotic resistance to be one of the biggest threats to global health, food security and development. Deaths attributable to AMR vary by area: The European Centre for Disease Prevention and Control calculated that in 2015 there were 671,689 infections in

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1764-442: A microbe. All types of microbes can develop drug resistance. Thus, there are antibiotic, antifungal, antiviral and antiparasitic resistance. Antibiotic resistance is a subset of antimicrobial resistance. This more specific resistance is linked to bacteria and thus broken down into two further subsets, microbiological and clinical. Microbiological resistance is the most common and occurs from genes, mutated or inherited, that allow

1911-487: A microbial community, it can then spread to other microbes in the community, potentially moving from a non-disease causing microbe to a disease-causing microbe. This process is heavily driven by the natural selection processes that happen during antibiotic use or misuse. Over time, most of the strains of bacteria and infections present will be the type resistant to the antimicrobial agent being used to treat them, making this agent now ineffective to defeat most microbes. With

2058-463: A million avoidable child deaths each year. Intermittent preventive therapy aimed at treating and preventing malaria episodes among pregnant women and young children is one public health measure in endemic countries. Since the 1980s, the growing field of population health has broadened the focus of public health from individual behaviors and risk factors to population-level issues such as inequality , poverty, and education. Modern public health

2205-466: A pattern which may have worsened during the COVID-19 pandemic. Studies have shown that common misconceptions about the effectiveness and necessity of antibiotics to treat common mild illnesses contribute to their overuse. Important to the conversation of antibiotic use is the veterinary medical system . Veterinary oversight is required by law for all medically important antibiotics. Veterinarians use

2352-650: A reduction of the prevalence of antimicrobial resistance in humans. In the United States the Veterinary Feed Directive went into practice in 2017 dictating that All medically important antibiotics to be used in feed or water for food animal species require a veterinary feed directive (VFD) or a prescription. Most pesticides protect crops against insects and plants, but in some cases antimicrobial pesticides are used to protect against various microorganisms such as bacteria, viruses, fungi, algae, and protozoa. The overuse of many pesticides in an effort to have

2499-407: A review of research on what local authorities can do to tackle obesity. The review covers interventions in the food environment (what people buy and eat), the built and natural environments , schools, and the community, as well as those focussing on active travel , leisure services and public sports, weight management programmes , and system-wide approaches . Health inequalities, driven by

2646-457: A screening of 3,537 articles published in Europe, Asia, and North America was done. Of the 55,225 total people surveyed in the articles, 70% had heard of antibiotic resistance previously, but 88% of those people thought it referred to some type of physical change in the human body. Clinical misuse by healthcare professionals is another contributor to increased antimicrobial resistance. Studies done in

2793-502: A series of publications on this topic in the late 1980s and early 1990s criticizing the UK's the Health of The Nation campaign. These publications exposed abuse of epidemiology and statistics by the public health movement to support lifestyle interventions and screening programs. A combination of inculcating a fear of ill-health and a strong notion of individual responsibility has been criticized as

2940-713: A significant AMR subset, enables bacteria to survive antibiotic treatment, complicating infection management and treatment options. Resistance arises through spontaneous mutation, horizontal gene transfer , and increased selective pressure from antibiotic overuse, both in medicine and agriculture, which accelerates resistance development. The burden of AMR is immense, with nearly 5 million annual deaths associated with resistant infections. Infections from AMR microbes are more challenging to treat and often require costly alternative therapies that may have more severe side effects. Preventive measures, such as using narrow-spectrum antibiotics and improving hygiene practices, aim to reduce

3087-491: A significant increase after World War II as concerns over the spread of disease as a result of globalization increased and the HIV/AIDS epidemic in sub-Saharan Africa surfaced. From 1990 to 2010, total health aid from developed countries increased from 5.5 billion to 26.87 billion with wealthy countries continuously donating billions of dollars every year with the goal of improving population health. Some efforts, however, receive

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3234-465: A significantly larger proportion of funds such as HIV which received an increase in funds of over $ 6 billion between 2000 and 2010 which was more than twice the increase seen in any other sector during those years. Health aid has seen an expansion through multiple channels including private philanthropy, non-governmental organizations , private foundations such as the Rockefeller Foundation or

3381-556: A virus for example. Excessive antimicrobial use has become one of the top contributors to the evolution of antimicrobial resistance. Since the beginning of the antimicrobial era, antimicrobials have been used to treat a wide range of infectious diseases. Overuse of antimicrobials has become the primary cause of rising levels of antimicrobial resistance. The main problem is that doctors are willing to prescribe antimicrobials to ill-informed individuals who believe that antimicrobials can cure nearly all illnesses, including viral infections like

3528-531: Is a fundamental part of population health. Scholars such as Coggon and Pielke express concerns about bringing general issues of wealth distribution into population health. Pielke worries about "stealth issue advocacy" in population health. Jung, Boris and Lushniak consider population health to be a concept that is the goal of an activity called public health practiced through the specialty preventive medicine. Lifestyle medicine uses individual lifestyle modification to prevent or revert disease and can be considered

3675-411: Is a major weakness, as livestock accounts for around 73% of global sales of antimicrobial agents, including antibiotics , antivirals , and antiparasitics . Considering the complex interactions between humans, animals and the environment, it is also important to consider the environmental aspects and contributors to antimicrobial resistance. Although there are still some knowledge gaps in understanding

3822-426: Is a naturally occurring process. Antimicrobial resistance can evolve naturally due to continued exposure to antimicrobials. Natural selection means that organisms that are able to adapt to their environment, survive, and continue to produce offspring. As a result, the types of microorganisms that are able to survive over time with continued attack by certain antimicrobial agents will naturally become more prevalent in

3969-431: Is a potential metric for the rate of AMR in the environment. This surveillance also allows for further investigation into the transmission routs between different ecosystems and human populations (including domesticated animals and livestock).   Such information gathered from wild bird biomes, can help identify patterns of diseased transmission and better target interventions.  These targeted interventions can inform

4116-545: Is an interdisciplinary field. For example, epidemiology , biostatistics , social sciences and management of health services are all relevant. Other important sub-fields include environmental health , community health , behavioral health , health economics , public policy , mental health , health education , health politics , occupational safety , disability , oral health , gender issues in health, and sexual and reproductive health . Public health, together with primary care , secondary care, and tertiary care ,

4263-503: Is an online global map of antimicrobial resistance developed by HealthMap which displays aggregated data on antimicrobial resistance from publicly available and user submitted data. The website can display data for a 25 miles (40 km) radius from a location. Users may submit data from antibiograms for individual hospitals or laboratories. European data is from the EARS-Net (European Antimicrobial Resistance Surveillance Network), part of

4410-409: Is dealing with the conflict between individual rights and maximizing right to health . Public health is justified by consequentialist utilitarian ideas, but is constrained and critiqued by liberal , deontological , principlist and libertarian philosophies Stephen Holland argues that it can be easy to find a particular framework to justify any viewpoint on public health issues, but that

4557-451: Is due to the activation of an evolved reward system for substances such as drugs, tobacco, alcohol , refined salt , fat , and carbohydrates . New technologies such as modern transportation also cause reduced physical activity . Research has found that behavior is more effectively changed by taking evolutionary motivations into consideration instead of only presenting information about health effects. The marketing industry has long known

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4704-543: Is illogical as antibiotics are used to treat infections and not prevent infections. 80% of antibiotic use in the U.S. is for agricultural purposes and about 70% of these are medically important. Overusing antibiotics gives the bacteria time to adapt leaving higher doses or even stronger antibiotics needed to combat the infection. Though antibiotics for growth promotion were banned throughout the EU in 2006, 40 countries worldwide still use antibiotics to promote growth. This can result in

4851-724: Is in agriculture. A majority of these products are used to help defend against the spread of infectious diseases, and hopefully protect public health. But out of the large amount of pesticides used, it is also estimated that less than 0.1% of those antimicrobial agents, actually reach their targets. That leaves over 99% of all pesticides used available to contaminate other resources. In soil, air, and water these antimicrobial agents are able to spread, coming in contact with more microorganisms and leading to these microbes evolving mechanisms to tolerate and further resist pesticides. The use of antifungal azole pesticides that drive environmental azole resistance have been linked to azole resistance cases in

4998-583: Is limited, the World Health Organization Advisory Group on Integrated Surveillance of Antimicrobial Resistance strongly recommended the reduction of use of medically important antimicrobials in livestock. Additionally, the Advisory Group stated that such antimicrobials should be expressly prohibited for both growth promotion and disease prevention in food producing animals. By mapping antimicrobial consumption in livestock globally, it

5145-465: Is limited. Public health programs providing vaccinations have made major progress in promoting health, including substantially reducing the occurrence of cholera and polio and eradicating smallpox , diseases that have plagued humanity for thousands of years. The World Health Organization (WHO) identifies core functions of public health programs including: In particular, public health surveillance programs can: The "Truth" campaign, launched by

5292-600: Is managed through a four level hierarchy from the national level down to the sub-district (Tuberculosis Unit) level. At the country level the program is led by the Central TB Division under the Ministry of Health and Family Welfare . The State TB Cell and the District TB Office govern the activities of the program at the state and district level respectively. At the sub-district/ Block level activities are organized under

5439-434: Is often concerned with addressing determinants of health across a population. There is a recognition that health is affected by many factors including class, race, income, educational status, region of residence, and social relationships ; these are known as " social determinants of health ". The upstream drivers such as environment, education, employment, income, food security, housing, social inclusion and many others effect

5586-519: Is one of Europe's most labor-intensive industries. In late 2020, it accounted for more than 21 million employment in the European Union when combined with social work. According to the WHO , several countries began the COVID-19 pandemic with insufficient health and care professionals, inappropriate skill mixtures, and unequal geographical distributions. These issues were worsened by the pandemic, reiterating

5733-530: Is part of a country's overall healthcare system. Public health is implemented through the surveillance of cases and health indicators , and through the promotion of healthy behaviors . Common public health initiatives include promotion of hand-washing and breastfeeding , delivery of vaccinations , promoting ventilation and improved air quality both indoors and outdoors , suicide prevention , smoking cessation , obesity education , increasing healthcare accessibility and distribution of condoms to control

5880-487: Is poor maternal and child health, exacerbated by malnutrition and poverty. The WHO reports that a lack of exclusive breastfeeding during the first six months of life contributes to over a million avoidable child deaths each year. Public health surveillance has led to the identification and prioritization of many public health issues facing the world today, including HIV/AIDS , diabetes , waterborne diseases , zoonotic diseases , and antibiotic resistance leading to

6027-514: Is related to public health. The American Board of Preventive Medicine separates three categories of preventive medicine: aerospace health, occupational health , and public health and general preventative medicine. Jung, Boris and Lushniak argue that preventive medicine should be considered the medical specialty for public health but note that the American College of Preventive Medicine and American Board of Preventive Medicine do not prominently use

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6174-435: Is scarce, but needed to support antibiotic stewardship in veterinary medicine. By comparison there is a lack of national and international monitoring programs for antifungal resistance. Antimicrobial stewardship programmes appear useful in reducing rates of antimicrobial resistance. The antimicrobial stewardship program will also provide pharmacists with the knowledge to educate patients that antibiotics will not work for

6321-540: Is the control of tobacco smoking . Many nations have implemented major initiatives to cut smoking, such as increased taxation and bans on smoking in some or all public places. Supporters argue by presenting evidence that smoking is one of the major killers, and that therefore governments have a duty to reduce the death rate, both through limiting passive (second-hand) smoking and by providing fewer opportunities for people to smoke. Opponents say that this undermines individual freedom and personal responsibility, and worry that

6468-516: Is through increased contact with densely populated areas, human waste, domestic animals, and domestic animal/livestock waste. Wild migrating birds interact with sedentary birds in different environments along their migration route.  This increases the rate and diversity of AMR across varying ecosystems. Neglect of wildlife in the global discussions surrounding health security and AMR, creates large barriers to true AMR surveillance. The surveillance of anti-microbial resistant organisms in wild birds

6615-1515: Is to improve the health of individuals and populations, and to increase life expectancy . Public health is a complex term, composed of many elements and different practices. It is a multi-faceted, interdisciplinary field. For example, epidemiology , biostatistics , social sciences and management of health services are all relevant. Other important sub-fields include environmental health , community health , behavioral health , health economics , public policy , mental health , health education , health politics , occupational safety , disability , gender issues in health, and sexual and reproductive health . Modern public health practice requires multidisciplinary teams of public health workers and professionals. Teams might include epidemiologists , biostatisticians , physician assistants , public health nurses , midwives , medical microbiologists , pharmacists , economists , sociologists , geneticists , data managers , environmental health officers ( public health inspectors ), bioethicists , gender experts, sexual and reproductive health specialists, physicians , and veterinarians . The elements and priorities of public health have evolved over time, and are continuing to evolve. Common public health initiatives include promotion of hand-washing and breastfeeding , delivery of vaccinations , suicide prevention , smoking cessation , obesity education , increasing healthcare accessibility and distribution of condoms to control

6762-504: The Bill & Melinda Gates Foundation , bilateral donors, and multilateral donors such as the World Bank or UNICEF . The result has been a sharp rise in uncoordinated and fragmented funding of an ever-increasing number of initiatives and projects. To promote better strategic cooperation and coordination between partners, particularly among bilateral development agencies and funding organizations,

6909-415: The COVID-19 pandemic redirected resources and scientific attention away from AMR, intensifying the challenge. The WHO defines antimicrobial resistance as a microorganism's resistance to an antimicrobial drug that was once able to treat an infection by that microorganism. A person cannot become resistant to antibiotics. Resistance is a property of the microbe, not a person or other organism infected by

7056-523: The ECDC . ResistanceMap is a website by the Center for Disease Dynamics, Economics & Policy and provides data on antimicrobial resistance on a global level. The WHO's AMR global action plan also recommends antimicrobial resistance surveillance in animals. Initial steps in the EU for establishing the veterinary counterpart EARS-Vet (EARS-Net for veterinary medicine) have been made. AMR data from pets in particular

7203-525: The Institute for Health Metrics and Evaluation and the World Health Organization has shown a link between international health aid in developing countries and a reduction in adult mortality rates. However, a 2014–2016 study suggests that a potential confounding variable for this outcome is the possibility that aid was directed at countries once they were already on track for improvement. That same study, however, also suggests that 1 billion dollars in health aid

7350-675: The Pharmacokinetic /pharmacodynamic model (PK/PD) approach to ensuring that the correct dose of the drug is delivered to the correct place at the correct timing. Increased antibiotic use during the early waves of the COVID-19 pandemic may exacerbate this global health challenge . Moreover, pandemic burdens on some healthcare systems may contribute to antibiotic-resistant infections. On the other hand, "increased hand hygiene, decreased international travel, and decreased elective hospital procedures may have reduced AMR pathogen selection and spread in

7497-686: The Swedish International Development Cooperation Agency (Sida) spearheaded the establishment of ESSENCE, an initiative to facilitate dialogue between donors/funders, allowing them to identify synergies. ESSENCE brings together a wide range of funding agencies to coordinate funding efforts. In 2009 health aid from the OECD amounted to $ 12.47 billion which amounted to 11.4% of its total bilateral aid. In 2009, Multilateral donors were found to spend 15.3% of their total aid on bettering public healthcare. Debates exist questioning

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7644-627: The United Nations hosting its first General Assembly Special Summit on the issue of non-communicable diseases in September 2011. There is a significant disparity in access to health care and public health initiatives between developed countries and developing countries , as well as within developing countries. In developing countries, public health infrastructures are still forming. There may not be enough trained health workers , monetary resources or, in some cases, sufficient knowledge to provide even

7791-530: The Ziehl–Neelsen staining technique, is conducted at the DMCs. This is the most widely available test with over 20,000 quality controlled laboratories across India. For diagnosis, two sputum samples are collected over two days (as spot-morning/morning-spot) from chest symptomatic (patients with presenting with a history of cough for two weeks or more) to arrive at a diagnosis. In addition to the test's high specificity ,

7938-516: The 30 most common infections in adults and children to reduce inappropriate prescribing in primary care and hospitals. Narrow-spectrum antibiotics are preferred due to their lower resistance potential, and broad-spectrum antibiotics are only recommended for people with more severe symptoms. Some antibiotics are more likely to confer resistance, so are kept as reserve antibiotics in the AWaRe book. Various diagnostic strategies have been employed to prevent

8085-445: The AMR umbrella, posing significant challenges to healthcare worldwide. Misuse and improper management of antimicrobials are primary drivers of this resistance, though it can also occur naturally through genetic mutations and the spread of resistant genes. Microbes resistant to multiple drugs are termed multidrug-resistant (MDR) and are sometimes called superbugs . Antibiotic resistance,

8232-588: The American Legacy Foundation in 2000. This campaign aimed to educate and discourage young people from smoking by exposing the tobacco industry's deceptive practices. Through a combination of powerful visuals, persuasive storytelling, and relatable messaging, the "Truth" campaign successfully reduced smoking rates among teenagers and young adults. Many health problems are due to maladaptive personal behaviors. From an evolutionary psychology perspective, over consumption of novel substances that are harmful

8379-622: The END TB targets 5 years earlier, RNTCP was renamed as the National TB Elimination Program. The change came into effect from 1 January 2020. This decision was declared by Special Secretary, Sanjeeva Kumar, Ministry of Health and Family Welfare, in a letter to all the State Chief Secretaries. Public health Public health is "the science and art of preventing disease, prolonging life and promoting health through

8526-409: The EU and European Economic Area caused by antibiotic-resistant bacteria, resulting in 33,110 deaths. Most were acquired in healthcare settings. In 2019 there were 133,000 deaths caused by AMR. AMR is driven largely by the misuse and overuse of antimicrobials. Yet, at the same time, many people around the world do not have access to essential antimicrobials. This leads to microbes either evolving

8673-494: The NTP, with assistance from international agencies, in 1993. Given TB's high curability rate 6–12 months after diagnosis, moving toward a clinical and treatment-based strategy was a sensible progression from the NTP. The Revised National TB Control Programme (RNTCP) thus formulated, adopted the internationally recommended Directly Observed Treatment Short-course (DOTS) strategy, as the most systematic and cost-effective approach to revitalise

8820-521: The RNTCP II remained almost the same as that of RNTCP I but additional requirements of quality assured diagnosis and treatment were built in through schemes to increase the participation of private sector providers and also inclusion of DOTS+ for MDR TB and XDR TB. Systematic research and evidence building to inform the programme for better design was also included as an important component. The Advocacy, Communication and Social Mobilization were also addressed in

8967-454: The RNTCP protocol is quite variable amongst private providers, and less than 1% of private providers comply with all RNTCP recommendations. There is need for regularizing the varied anti-tubercular treatment regimens used by general practitioners and other private sector players. The treatment carried out by the private practitioners vary from that of the RNTCP treatment. Once treatment is started in

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9114-705: The Revised National Tuberculosis Control Program (RNTCP) in 1997 and then into the National Tuberculosis Elimination program in 2020. TB control efforts got organized with the National TB program (NTP) primarily focusing on BCG vaccinations as a preventive measure. At that time, the Indian government lacked the financial backing to meet its public health goals. Therefore, external sources of funding and administration, often from

9261-597: The State level, a State TB Officer and at District level a District TB Officer manages the program. Diagnostic services under the program are provided through a network of various types of laboratories operating in a three tier fashion. At the service/ facility level there are microscopy and rapid molecular tests, constituting the first tier. The second tier is constituted by Intermediate Reference Laboratories(IRL) and Culture and Drug Susceptibility Testing (C&DST) Labs, which provide advanced DST facilities and supervisory support to

9408-498: The TB control programme in India. DOTS was adopted as a strategy for provision of treatment to increase the treatment completion rates. Political and administrative commitment were some of its core strategies, to ensure the provision of organized and comprehensive TB control services was obtained. Adoption of smear microscopy for reliable and early diagnosis was introduced in a decentralized manner in

9555-699: The Tuberculosis Unit (TB Unit). The Central TB Division is headed by a Deputy Director General - TB (DDG-TB) and is the National Program Manager. The administrative command falls to the Additional Secretary and Director General (NTEP and NACO ) and the Joint Secretary-TB. Under the Central TB Division, a number of National Level Expert Committees and National Institutes for Tuberculosis, advise and assist in various programmatic functions. At

9702-800: The UK," highlights the urgency of reevaluating antibiotic treatment durations amidst the global challenge of antimicrobial resistance (AMR). It investigates the effectiveness of shorter versus longer antibiotic regimens for respiratory tract infections (RTIs) in a UK secondary care setting, emphasizing the need for evidence-based prescribing practices to optimize patient outcomes and combat AMR. There are multiple national and international monitoring programs for drug-resistant threats, including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant S. aureus (VRSA), extended spectrum beta-lactamase (ESBL) producing Enterobacterales , vancomycin-resistant Enterococcus (VRE), and multidrug-resistant Acinetobacter baumannii (MRAB). ResistanceOpen

9849-583: The US show that the indication for treatment of antibiotics, choice of the agent used, and the duration of therapy was incorrect in up to 50% of the cases studied. In 2010 and 2011 about a third of antibiotic prescriptions in outpatient settings in the United States were not necessary. Another study in an intensive care unit in a major hospital in France has shown that 30% to 60% of prescribed antibiotics were unnecessary. These inappropriate uses of antimicrobial agents promote

9996-580: The WHO and UN, became common in the realm of public health. In 1992, the WHO and Swedish International Development Agency evaluated the NTCP, finding that it lacked funding, information on health outcomes, consistency across management and treatment regimens, and efficient diagnostic techniques. In order to overcome the deficiencies of the NTP, the Government decided to give a new thrust to TB control activities by revitalising

10143-452: The age of five were overweight in 2014. Once considered a problem in high-income countries, it is now on the rise in low-income countries, especially in urban settings. Many public health programs are increasingly dedicating attention and resources to the issue of obesity, with objectives to address the underlying causes including healthy diet and physical exercise . The National Institute for Health and Care Research (NIHR) has published

10290-503: The aggressive prescription of antibiotics as necessary to avoid failing to provide adequate care. This demonstrates how a majority of doctors underestimate the impact that their own prescribing habits have on antimicrobial resistance as a whole. It also confirms that some physicians may be overly cautious and prescribe antibiotics for both medical or legal reasons, even when clinical indications for use of these medications are not always confirmed. This can lead to unnecessary antimicrobial use,

10437-515: The amount of anti-microbial resistance (AMR) to the bird population.  The introduction of AMR to wild birds positively correlates with human pollution and increased human contact.  Additionally, wild birds can participate in horizontal gene transfer with bacteria, leading to the transmission of antibiotic-resistant genes (ARG). For simplicity, wild bird populations can be divided into two major categories, wild sedentary birds and wild migrating birds.  Wild sedentary bird exposure to AMR

10584-405: The authors opined that "The fact that type 2 diabetes, a largely preventable disorder, has reached epidemic proportion is a public health humiliation." The risk of type 2 diabetes is closely linked with the growing problem of obesity . The WHO's latest estimates as of June 2016 highlighted that globally approximately 1.9 billion adults were overweight in 2014, and 41 million children under

10731-492: The bacteria to resist the mechanism to kill the microbe associated with certain antibiotics. Clinical resistance is shown through the failure of many therapeutic techniques where the bacteria that are normally susceptible to a treatment become resistant after surviving the outcome of the treatment. In both cases of acquired resistance, the bacteria can pass the genetic catalyst for resistance through horizontal gene transfer: conjugation, transduction , or transformation . This allows

10878-422: The beginnings of human civilization , communities promoted health and fought disease at the population level. In complex , pre-industrialized societies , interventions designed to reduce health risks could be the initiative of different stakeholders, such as army generals, the clergy or rulers. Great Britain became a leader in the development of public health initiatives, beginning in the 19th century, due to

11025-669: The burden of disease and inequality faced by developing countries and lead to a healthier future. The links between the various sustainable development goals and public health are numerous and well established. Antimicrobial resistance Antimicrobial resistance ( AMR or AR ) occurs when microbes evolve mechanisms that protect them from antimicrobials , which are drugs used to treat infections. This resistance affects all classes of microbes, including bacteria ( antibiotic resistance), viruses ( antiviral resistance), protozoa ( antiprotozoal resistance), and fungi ( antifungal resistance). Together, these adaptations fall under

11172-443: The chances of members of the population acquiring a mutation that increases resistance. Many individuals stop taking antibiotics when they begin to feel better. When this occurs, it is possible that the microbes that are less susceptible to treatment still remain in the body. If these microbes are able to continue to reproduce, this can lead to an infection by bacteria that are less susceptible or even resistant to an antibiotic. AMR

11319-518: The clinical setting. The same issues confront the novel antifungal classes (e.g. orotomides ) which are again being used in both the clinic and agriculture. Wildlife, including wild and migratory birds , serve as a reservoir for zoonotic disease and antimicrobial-resistant organisms.  Birds are a key link between the transmission of zoonotic diseases to human populations.  By the same token, increased contact between wild birds and human populations (including domesticated animals), has increased

11466-401: The common cold. In an analysis of drug prescriptions, 36% of individuals with a cold or an upper respiratory infection (both usually viral in origin) were given prescriptions for antibiotics. These prescriptions accomplished nothing other than increasing the risk of further evolution of antibiotic resistant bacteria. Using antimicrobials without prescription is another driving force leading to

11613-427: The contemporary bacteria from the active layer of thawed ground above them, which may mean that this risk is "no greater" than from any other soil. There have been increasing public calls for global collective action to address the threat, including a proposal for an international treaty on antimicrobial resistance. Further detail and attention is still needed in order to recognize and measure trends in resistance on

11760-458: The correct approach is to find a framework that best describes a situation and see what it implies about public health policy. The definition of health is vague and there are many conceptualizations. Public health practitioners definition of health can different markedly from members of the public or clinicians . This can mean that members of the public view the values behind public health interventions as alien which can cause resentment amongst

11907-629: The country, at the district and in some cases at a sub-district level. Advanced tests such as the Line Probe Assay, Liquid and Solid Culture, and Drug Susceptibility Testing are available at C&DST(Culture and Drug Sensitivity Testing) Labs are located at a few select places in the state, often within the IRL; these provide additional drug resistance/ susceptibility testing services for a number of Anti-TB drugs. Standardized treatment regimen composed of multiple anti-Tuberculosis drugs are provided through

12054-479: The country. As per the National Strategic Plan 2017–25, the program has a vision of achieving a "TB free India",with a strategies under the broad themes of "Prevent, Detect,Treat and Build pillars for universal coverage and social protection". The program provides, various free of cost, quality tuberculosis diagnosis and treatment services across the country through the government health system. The program

12201-461: The design. The challenges imposed by the structures under NRHM were also taken into account. NIKSHAY, the web based reporting for TB programme has been another notable achievement initiated in 2012 and has enabled capture and transfer of individual patient data from the remotest health institutions of the country. Consolidating a series of rapid and progressive advancements in RNTCP from 2016 onward, and with Government of India's commitment to achieve

12348-419: The distribution of health between and within populations and are often shaped by policy. A social gradient in health runs through society. The poorest generally have the worst health, but even the middle classes will generally have worse health outcomes than those of a higher social level. The new public health advocates for population-based policies that improve health in an equitable manner. The health sector

12495-404: The effects of chronic diseases as life expectancy increases, the poorer communities being heavily affected by both chronic and infectious diseases. Another major public health concern in the developing world is poor maternal and child health, exacerbated by malnutrition and poverty. The WHO reports that a lack of exclusive breastfeeding during the first six months of life contributes to over

12642-422: The efficacy of international health aid. Supporters of aid claim that health aid from wealthy countries is necessary in order for developing countries to escape the poverty trap . Opponents of health aid claim that international health aid actually disrupts developing countries' course of development, causes dependence on aid, and in many cases the aid fails to reach its recipients. For example, recently, health aid

12789-494: The environment, and those without this resistance will become obsolete. Some contemporary antimicrobial resistances have also evolved naturally before the use of antimicrobials of human clinical uses. For instance, methicillin -resistance evolved as a pathogen of hedgehogs , possibly as a co-evolutionary adaptation of the pathogen to hedgehogs that are infected by a dermatophyte that naturally produces antibiotics. Also, many soil fungi and bacteria are natural competitors and

12936-399: The evolution of antimicrobial resistance by supporting the bacteria in developing genetic alterations that lead to resistance. According to research conducted in the US that aimed to evaluate physicians' attitudes and knowledge on antimicrobial resistance in ambulatory settings, only 63% of those surveyed reported antibiotic resistance as a problem in their local practices, while 23% reported

13083-755: The fact that it was the first modern urban nation worldwide. The public health initiatives that began to emerge initially focused on sanitation (for example, the Liverpool and London sewerage systems ), control of infectious diseases (including vaccination and quarantine ) and an evolving infrastructure of various sciences, e.g. statistics, microbiology, epidemiology, sciences of engineering. Public health has been defined as "the science and art of preventing disease ", prolonging life and improving quality of life through organized efforts and informed choices of society , organizations (public and private), communities and individuals . The public can be as small as

13230-445: The first tier. The National Reference Laboratories constitute the third tier, and provide quality assurance and certification services for C&DST labs and co-ordinate with WHO Supra National Reference Laboratory Network. In addition to the above, Chest Radiography, available at tertiary and secondary healthcare levels, also play an important role in screening for Tuberculosis signs and clinical diagnosis. Sputum smear microscopy, using

13377-487: The food industry, specifically with food producing animals. With an ever-increasing human population, there is constant pressure to intensify productivity in many agricultural sectors, including the production of meat as a source of protein. Antibiotics are fed to livestock to act as growth supplements, and a preventive measure to decrease the likelihood of infections. Farmers typically use antibiotics in animal feed to improve growth rates and prevent infections. However, this

13524-515: The general health services. Supply of drugs was also strengthened to provide assured supply of drugs to meet the requirements of the system. The RNTCP was built on the infrastructure and systems built through the NTP. Major additions to the RNTCP, over and above the structures established under the NTP, was the establishment of a sub-district supervisory unit, known as a TB Unit, with dedicated RNTCP supervisors posted, and decentralization of both diagnostic and treatment services, with treatment given under

13671-448: The harmful and undesirable effects of tobacco smoking on other persons and imposing smoking bans in public places have been particularly effective in reducing tobacco smoking. Public libraries can also be beneficial tools for public health changes. They provide access to healthcare information, link people to healthcare services, and even can provide direct care in certain situations. As well as seeking to improve population health through

13818-796: The highest possible level of health". The WHO's broad mandate includes advocating for universal healthcare, monitoring public health risks, coordinating responses to health emergencies, and promoting human health and well-being. The WHO has played a leading role in several public health achievements, most notably the eradication of smallpox , the near- eradication of polio , and the development of an Ebola vaccine . Its current priorities include communicable diseases , particularly HIV/AIDS , Ebola , COVID-19 , malaria and tuberculosis ; non-communicable diseases such as heart disease and cancer; healthy diet , nutrition, and food security ; occupational health ; and substance abuse . Most countries have their own governmental public health agency, often called

13965-446: The implementation of specific population-level interventions, public health contributes to medical care by identifying and assessing population needs for health care services, including: Some programs and policies associated with public health promotion and prevention can be controversial. One such example is programs focusing on the prevention of HIV transmission through safe sex campaigns and needle-exchange programs . Another

14112-487: The importance of associating products with high status and attractiveness to others. Films are increasingly being recognized as a public health tool, with the Harvard University 's T.H. Chan School of Public Health categorizing such films as "impact filmmaking." In fact, film festivals and competitions have been established to specifically promote films about health. Conversely, it has been argued that emphasizing

14259-441: The importance of public health programs in reducing the incidence of disease, disability, and the effects of aging and other physical and mental health conditions. However, public health generally receives significantly less government funding compared with medicine. Although the collaboration of local health and government agencies is considered best practice to improve public health, the pieces of evidence available to support this

14406-477: The importance of public health. In the United States, a history of underinvestment in public health undermined the public health workforce and support for population health, long before the pandemic added to stress, mental distress, job dissatisfaction, and accelerated departures among public health workers. Health aid to developing countries is an important source of public health funding for many developing countries. Health aid to developing countries has shown

14553-718: The inability of known causative agents of contagious diseases to survive being frozen and thawed makes this threat unlikely. Instead, there have been suggestions that when modern pathogenic bacteria interact with the ancient ones, they may, through horizontal gene transfer , pick up genetic sequences which are associated with antimicrobial resistance, exacerbating an already difficult issue. Antibiotics to which permafrost bacteria have displayed at least some resistance include chloramphenicol , streptomycin , kanamycin , gentamicin , tetracycline , spectinomycin and neomycin . However, other studies show that resistance levels in ancient bacteria to modern antibiotics remain lower than in

14700-416: The increased use of antimicrobial agents, there is a speeding up of this natural process. In the vast majority of countries, antibiotics can only be prescribed by a doctor and supplied by a pharmacy. Self-medication by consumers is defined as "the taking of medicines on one's own initiative or on another person's suggestion, who is not a certified medical professional", and it has been identified as one of

14847-454: The infection and other health problems a person may have. For many infections once a person has improved there is little evidence that stopping treatment causes more resistance. Some, therefore, feel that stopping early may be reasonable in some cases. Other infections, however, do require long courses regardless of whether a person feels better. Delaying antibiotics for ailments such as a sore throat and otitis media may have not different in

14994-402: The intensive phase of two months and HRE for the continuation phase of four months. For drug resistant cases, depending upon the pattern of drug resistance a number of regimen are available composed of a combination of 13 drugs. In India a sizable proportion of the people with symptoms suggestive of pulmonary tuberculosis approach the private sector for their immediate health care needs. However,

15141-501: The international level; the idea of a global tracking system has been suggested but implementation has yet to occur. A system of this nature would provide insight to areas of high resistance as well as information necessary for evaluating programs, introducing interventions and other changes made to fight or reverse antibiotic resistance. Delaying or minimizing the use of antibiotics for certain conditions may help safely reduce their use. Antimicrobial treatment duration should be based on

15288-401: The lack of knowledge of the public on, firstly, the dangerous effects of certain antimicrobials (for example ciprofloxacin which can cause tendonitis , tendon rupture and aortic dissection ) and, secondly, broad microbial resistance and when to seek medical care if the infection is not clearing. In order to determine the public's knowledge and preconceived notions on antibiotic resistance,

15435-419: The majority of antibiotics being used in the community rather than hospitals. The prevalence of self-medication in low- and middle-income countries (LMICs) ranges from 8.1% to 93%. Accessibility, affordability, and conditions of health facilities, as well as the health-seeking behavior, are factors that influence self-medication in low- and middle-income countries. Two significant issues with self-medication are

15582-400: The mechanisms and transmission pathways, environmental pollution is considered a significant contributor to antimicrobial resistance. Important contributing factors are through "antibiotic residues", "industrial effluents", " agricultural runoffs ", "heavy metals", " biocides and pesticides " and "sewage and wastewater" that create reservoirs for resistant genes and bacteria that facilitates

15729-892: The ministry of health, with responsibility for domestic health issues. For example, in the United States , state and local health departments are on the front line of public health initiatives. In addition to their national duties, the United States Public Health Service (PHS), led by the Surgeon General of the United States Public Health Service , and the Centers for Disease Control and Prevention , headquartered in Atlanta , are also involved with international health activities. Most governments recognize

15876-532: The needs of the normative group. Identifying bias within public health research and practice is essential to ensuring public health efforts mitigate and don't aggravate health inequities. The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution, which establishes the agency's governing structure and principles, states its main objective as "the attainment by all peoples of

16023-400: The next six years. In their first major declaration on the issue since 2016, global leaders also committed to raising $ 100 million to update and implement AMR action plans. However, the final draft of the declaration omitted an earlier target to reduce antibiotic use in animals by 30% by 2030, due to opposition from meat-producing countries and the farming industry. Critics argue this omission

16170-530: The organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the determinants of health of a population and the threats it faces is the basis for public health. The public can be as small as a handful of people or as large as a village or an entire city; in the case of a pandemic it may encompass several continents. The concept of health takes into account physical, psychological , and social well-being , among other factors. Public health

16317-444: The original antibiotic penicillin discovered by Alexander Fleming rapidly lost clinical effectiveness in treating humans and, furthermore, none of the other natural penicillins (F, K, N, X, O, U1 or U6) are currently in clinical use. Antimicrobial resistance can be acquired from other microbes through swapping genes in a process termed horizontal gene transfer . This means that once a gene for resistance to an antibiotic appears in

16464-506: The overuse of antibiotics to self-treat diseases like the common cold, cough, fever, and dysentery resulting in an epidemic of antibiotic resistance in countries like Bangladesh, risking its spread around the globe. Introducing strict antibiotic stewardship in the outpatient setting to reduce inappropriate prescribing of antibiotics may reduce the emerging bacterial resistance. The WHO AWaRe (Access, Watch, Reserve) guidance and antibiotic book has been introduced to guide antibiotic choice for

16611-426: The overuse of antifungal therapy in the clinic, proving a safe alternative to empirical antifungal therapy, and thus underpinning antifungal stewardship schemes. Antimicrobial stewardship teams in hospitals are encouraging optimal use of antimicrobials. The goals of antimicrobial stewardship are to help practitioners pick the right drug at the right dose and duration of therapy while preventing misuse and minimizing

16758-450: The permafrost, and it is possible for microorganisms to resume their life functions once it thaws. While some common pathogens such as influenza , smallpox or the bacteria associated with pneumonia have failed to survive intentional attempts to revive them, more cold-adapted microorganisms such as anthrax , or several ancient plant and amoeba viruses, have successfully survived prolonged thaw. Some scientists have argued that

16905-452: The prevalence of infectious diseases decreased through the 20th century , public health began to put more focus on chronic diseases such as cancer and heart disease . Previous efforts in many developed countries had already led to dramatic reductions in the infant mortality rate using preventive methods. In Britain, the infant mortality rate fell from over 15% in 1870 to 7% by 1930. A major public health concern in developing countries

17052-406: The primary reasons for the evolution of antimicrobial resistance. Self-medication with antibiotics is an unsuitable way of using them but a common practice in resource-constrained countries. The practice exposes individuals to the risk of bacteria that have developed antimicrobial resistance. Many people resort to this out of necessity, when access to a physician is unavailable, or when patients have

17199-402: The private sector is overburdened, and lacks the capacity to treat such high volumes of patients. RNTCP-recommended Private-Provider Interface Agencies (PPIAs) help treat and track high volumes of patients through offering treatment vouchers, electronic case notification, and information systems for patient tracking. Due to lacking training and coordination amongst private providers, adherence to

17346-488: The problem. It is possible that as many as 1 in 3 prescriptions written for antibiotics are unnecessary. Every year, approximately 154 million prescriptions for antibiotics are written. Of these, up to 46 million are unnecessary or inappropriate for the condition that the patient has. Microbes may naturally develop resistance through genetic mutations that occur during cell division, and although random mutations are rare, many microbes reproduce frequently and rapidly, increasing

17493-588: The program. Typically, drug regimen consist of an intensive phase of about two to six months and a longer continuation phase of four to one and half years. Based on the nature of anti-microbial resistance to the disease different treatment regimen are offered through the program. New Cases and those which exhibit no resistance are offered a six-month, short course of the four first line drugs; Isoniazid -H: Rifampicin -R, Pyrazinamide -Z, and Ethambutol -E. The drugs are administered through daily weight band based doses of Fixed Dose Combinations , consisting of HRZE for

17640-575: The programme over the previous 12-year period, from 2006 onwards. During this period the programme aimed to widen services both in terms of activities and access, and to sustain the achievements. The second phase aimed to maintain at least a 70% case detection rate of new smear positive cases as well as maintain a cure rate of at least 85%, in order to achieve the TB-related targets set by the Millennium Development Goals for 2015. The design of

17787-484: The public towards certain interventions. Such vagueness can be a problem for health promotion . Critics have argued that public health tends to place more focus on individual factors associated with health at the expense of factors operating at the population level. Historically, public health campaigns have been criticized as a form of " healthism ", as moralistic in nature rather than being focused on health. Medical doctors, Petr Shkrabanek and James McCormick wrote

17934-410: The rate of complications compared with immediate antibiotics, for example. When treating respiratory tract infections , clinical judgement is required as to the appropriate treatment (delayed or immediate antibiotic use). The study, "Shorter and Longer Antibiotic Durations for Respiratory Infections: To Fight Antimicrobial Resistance—A Retrospective Cross-Sectional Study in a Secondary Care Setting in

18081-427: The reemergence of infectious diseases such as tuberculosis . Antibiotic resistance , also known as drug resistance, was the theme of World Health Day 2011 . For example, the WHO reports that at least 220 million people worldwide have diabetes. Its incidence is increasing rapidly, and it is projected that the number of diabetes deaths will double by 2030. In a June 2010 editorial in the medical journal The Lancet ,

18228-449: The resistance to spread across the same species of pathogen or even similar bacterial pathogens. WHO report released April 2014 stated, "this serious threat is no longer a prediction for the future, it is happening right now in every region of the world and has the potential to affect anyone, of any age, in any country. Antibiotic resistance—when bacteria change so antibiotics no longer work in people who need them to treat infections—is now

18375-447: The resources deployed were developed and thus the formation of the State and District TB Control Societies was under- taken. The systems were further strengthened and the programme was scaled up for national coverage in 2005. India achieved country wide coverage under RNTCP in March 2006. This was followed up with RNTCP Phase II, developed based on the lessons learnt from the implementation of

18522-419: The short term" during the COVID-19 pandemic. The use of disinfectants such as alcohol-based hand sanitizers, and antiseptic hand wash may also have the potential to increase antimicrobial resistance. Extensive use of disinfectants can lead to mutations that induce antimicrobial resistance. A 2024 United Nations High-Level Meeting on AMR has pledged to reduce deaths associated with bacterial AMR by 10% over

18669-409: The simple act of handwashing with soap can prevent the spread of many contagious diseases . In other cases, treating a disease or controlling a pathogen can be vital to preventing its spread to others, either during an outbreak of infectious disease or through contamination of food or water supplies. Public health, together with primary care , secondary care, and tertiary care , is part of

18816-591: The social determinants of health, are also a growing area of concern in public health. A central challenge to securing health equity is that the same social structures that contribute to health inequities also operate and are reproduced by public health organizations. In other words, public health organizations have evolved to better meet the needs of some groups more than others. The result is often that those most in need of preventative interventions are least likely to receive them and interventions can actually aggravate inequities as they are often inadvertently tailored to

18963-409: The spread of sexually transmitted diseases . Public health aims are achieved through surveillance of cases and the promotion of healthy behaviors , communities and environments . Analyzing the determinants of health of a population and the threats it faces is the basis for public health. Many diseases are preventable through simple, nonmedical methods. For example, research has shown that

19110-438: The spread of sexually transmitted diseases . There is a significant disparity in access to health care and public health initiatives between developed countries and developing countries , as well as within developing countries. In developing countries, public health infrastructures are still forming. There may not be enough trained healthcare workers , monetary resources, or, in some cases, sufficient knowledge to provide even

19257-605: The spread of resistance. The WHO claims that AMR is one of the top global public health and development threats, estimating that bacterial AMR was directly responsible for 1.27 million global deaths in 2019 and contributed to 4.95 million deaths . Moreover, the WHO and other international bodies warn that AMR could lead to up to 10 million deaths annually by 2050 unless actions are taken. Global initiatives, such as calls for international AMR treaties, emphasize coordinated efforts to limit misuse, fund research, and provide access to necessary antimicrobials in developing nations. However,

19404-418: The state may be encouraged to remove more and more choice in the name of better population health overall. Psychological research confirms this tension between concerns about public health and concerns about personal liberty: (i) the best predictor of complying with public health recommendations such as hand-washing, mask-wearing, and staying at home (except for essential activity) during the COVID-19 pandemic

19551-511: The strictest sense. For example, mandating the use of seat belts in cars can save countless lives and contribute to the health of a population, but typically money spent enforcing this rule would not count as money spent on health care. Large parts of the world remained plagued by largely preventable or treatable infectious diseases. In addition to this however, many developing countries are also experiencing an epidemiological shift and polarization in which populations are now experiencing more of

19698-426: The support of DOT (directly observed treatment) providers. Large-scale implementation of the RNTCP began in late 1998. Expansion of the programme was undertaken in a phased manner with rigid appraisals of the districts prior to starting service delivery. In the first phase of RNTCP (1998–2005), the programme's focus was on ensuring expansion of quality DOTS services to the entire country. The initial 5-year project plan

19845-502: The term "public health". Preventive medicine specialists are trained as clinicians and address complex health needs of a population such as by assessing the need for disease prevention programs, using the best methods to implement them, and assessing their effectiveness. Since the 1990s many scholars in public health have been using the term population health . There are no medical specialties directly related to population health. Valles argues that consideration of health equity

19992-814: The transfer of human pathogens. Unused or expired antibiotics, if not disposed of properly, can enter water systems and soil. Discharge from pharmaceutical manufacturing and other industrial companies can also introduce antibiotics and other chemicals into the environment. These factors allow for creating selective pressure for resistant bacteria. Antibiotics used in livestock and aquaculture can contaminate soil and water, which promotes resistance in environmental microbes. Heavy metals such as zinc , copper and mercury , and also biocides and pesticides, can co- select for antibiotic resistance, enhancing their speed. Inadequate treatment of sewage and wastewater allows resistant bacteria and genes to spread through water systems. The antimicrobial resistance crisis also extends to

20139-413: The transfer of resistant bacterial strains into the food that humans eat, causing potentially fatal transfer of disease. While the practice of using antibiotics as growth promoters does result in better yields and meat products, it is a major issue and needs to be decreased in order to prevent antimicrobial resistance. Though the evidence linking antimicrobial usage in livestock to antimicrobial resistance

20286-404: The use of antimicrobial agents and reduce the persistence of multi-drug resistant organisms. Permafrost is a term used to refer to any ground that remained frozen for two years or more, with the oldest known examples continuously frozen for around 700,000 years. In the recent decades, permafrost has been rapidly thawing due to climate change . The cold preserves any organic matter inside

20433-588: The use of two samples ensures that the diagnostic procedure has a high (>99%) test sensitivity as well. Cartridge Based Nucleic Acid Amplification Test (CBNAAT) using the GeneXpert Platform, and TruNat are rapid molecular tests for TB diagnosis and Rifampicin resistance detection . This test is the first choice of diagnostic test for high risk population, children, contacts of drug resistant cases and PLHA(Patient Living With HIV AIDS) . Currently there are about 1200 CBNAAT and 200 TruNat laboratories in

20580-459: The usual way for the private sector, it is difficult for the patient to change to the RNTCP panel. Studies have shown that faulty anti-TB prescriptions in the private sector in India ranges from 50% to 100% and this is a matter of concern for the healthcare services in TB currently being provided by the largely unregulated private sector in India. India has had a TB Control Program since 1962. Since then it has re-organized itself two times; first into

20727-462: The worldwide context. It has been defined as "the area of study, research and practice that places a priority on improving health and achieving equity in " Health for all " people worldwide". International health is a field of health care, usually with a public health emphasis, dealing with health across regional or national boundaries. Public health is not the same as public healthcare ( publicly funded health care ). The term preventive medicine

20874-418: Was a leader in the development of public health during that time period out of necessity: Great Britain was the first modern urban nation (by 1851 more than half of the population lived in settlements of more than 2000 people). This led to a certain type of distress which then led to public health initiatives. Later that particular concern faded away. With the onset of the epidemiological transition and as

21021-882: Was associated with 364,000 fewer deaths occurring between ages 0 and 5 in 2011. To address current and future challenges in addressing health issues in the world, the United Nations have developed the Sustainable Development Goals to be completed by 2030. These goals in their entirety encompass the entire spectrum of development across nations, however Goals 1–6 directly address health disparities , primarily in developing countries. These six goals address key issues in global public health , poverty , hunger and food security , health, education, gender equality and women's empowerment , and water and sanitation . Public health officials can use these goals to set their own agenda and plan for smaller scale initiatives for their organizations. These goals are designed to lessen

21168-408: Was funneled towards initiatives such as financing new technologies like antiretroviral medication , insecticide-treated mosquito nets , and new vaccines. The positive impacts of these initiatives can be seen in the eradication of smallpox and polio ; however, critics claim that misuse or misplacement of funds may cause many of these efforts to never come into achievement. Economic modeling based on

21315-420: Was people's perceived duties to prevent harm but (ii) the best predictor of flouting such public health recommendations was valuing liberty more than equality. Simultaneously, while communicable diseases have historically ranged uppermost as a global health priority, non-communicable diseases and the underlying behavior-related risk factors have been at the bottom. This is changing, however, as illustrated by

21462-409: Was predicted that in 228 countries there would be a total 67% increase in consumption of antibiotics by livestock by 2030. In some countries such as Brazil, Russia, India, China, and South Africa it is predicted that a 99% increase will occur. Several countries have restricted the use of antibiotics in livestock, including Canada, China, Japan, and the US. These restrictions are sometimes associated with

21609-492: Was to implement the RNTCP in 102 districts of the country and strengthen another 203 Short Course Chemotherapy (SCC) districts for introduction of the revised strategy at a later stage. The Government of India took up the massive challenge of nationwide expansion of the RNTCP and covering the whole country under RNTCP by the year 2005, and to reach the global targets for TB control on case detection and treatment success. The structural arrangements for funds transfer and to account for

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