82-520: NZ Truth was a tabloid newspaper published weekly in New Zealand from 1905 to 2013. NZ Truth was founded in 1905 by Australian John Norton in Wellington , as a New Zealand edition of his Sydney Truth , aiming a sensational blend of sex, crime and radical politics at mainly working class readers. According to newspaper historian (and former NZ Truth journalist) Redmer Yska, English-born Norton
164-456: A 10% stake in German biotech company CureVac . In March 2018, GSK announced that it has reached an agreement with Novartis to acquire Novartis's 36.5% stake in their Consumer Healthcare Joint Venture for US$ 13 billion (£9.2 billion). In December 2018, GSK announced that it, along with Pfizer , had reached an agreement to merge and combine their consumer healthcare divisions into
246-570: A German biotech company, for US$ 98 million, and in June, worldwide rights to alitretinoin (Toctino), an eczema drug, for US$ 302 million. In 2013, GSK acquired Human Genome Sciences (HGS) for US$ 3 billion; the companies had collaborated on developing the lupus drug Belimumab (Benlysta), albiglutide for type 2 diabetes , and darapladib for atherosclerosis , and in September, sold its beverage division to Suntory . This included
328-473: A Labour government passed a law restricting coverage to the bare bones of proceedings, removing a vital part of Truth's editorial 'bread and butter'. In 1963, as revelations of a seamy British political scandal unfolded, audited circulation reached a peak of 240,000, and the weekly claimed a readership of a million Kiwis. But the advent of television in 1960, the decriminalisation of Sunday newspapers in 1963 and changing attitudes to sexual morality associated with
410-507: A Medicines Research Centre in Stevenage , Hertfordshire . Also that year, Glaxo Wellcome acquired the California -based Affymax, a leader in the field of combinatorial chemistry . By 1999, Glaxo Wellcome had become the world's third-largest pharmaceutical company by revenues (behind Novartis and Merck), with a global market share of around 4 per cent. Its products included Imigran (for
492-856: A New Zealand consortium led by the paper's legal representative James Dunn and his former Scots College schoolmate Cliff Plimmer. Over the next few decades, the New Zealand owners would refashion NZ Truth into what Yska calls 'a shrill megaphone for a conservative establishment holding back political, social and cultural ties that increasingly threatened to sweep it away.' Over the decades, NZ Truth variously employed well-known New Zealand authors, including Robin Hyde in 1928. As in Australia, NZ Truth capitalised on unrestricted press coverage of divorce cases during its first half century, with court evidence of adultery cases given lengthy, invariably saucy treatment. In 1958,
574-678: A Swiss pharmaceutical company, for US$ 190 million, and in June that year that it would sell two meningitis drugs to Pfizer , Nimenrix and Mencevax for around US$ 130 million. Philip Hampton , at that time chair of the Royal Bank of Scotland , became GSK chairman in September 2015. On 31 March 2017, Emma Walmsley became CEO . She is the first female CEO of the company. In December 2017, Reuters reported that Glaxo had increased its stake in its Saudi Arabian unit to 75% (from 49%) taking over control from its Saudi partner Banaja KSA Holding Company. With respect to rare diseases ,
656-505: A US$ 660-million deal, Prestige Brands Holdings took over 17 GSK brands with sales of US$ 210 million, including BC Powder , Beano , Ecotrin , Fiber Choice, Goody's Powder , Sominex and Tagamet . In 2012, the company announced that it would invest £500 million in manufacturing facilities in Ulverston , northern England, designating it as the site for a previously announced biotech plant. In May that year it acquired CellZome,
738-464: A broadsheet. Its sister publication, Meia Hora has always been a tabloid, but in slightly smaller format than O Dia and Lance! . The more recent usage of the term 'tabloid' refers to weekly or semi-weekly newspapers in tabloid format. Many of these are essentially straightforward newspapers, publishing in tabloid format, because subway and bus commuters prefer to read smaller-size newspapers due to lack of space. These newspapers are distinguished from
820-755: A business doing research into animal health, and Recherche et Industrie Thérapeutiques in Belgium in 1963, to focus on vaccines. The company began to expand globally, buying seven laboratories in Canada and the United States in 1969. In 1982, it bought Allergan , a manufacturer of eye and skincare products. Smith Kline & French merged with Beckman Inc. in 1982, and changed its name to SmithKline Beckman . In 1988, it bought International Clinical Laboratories. In 1989, SmithKline Beckman merged with Beecham Group to form SmithKline Beecham P.L.C. . The headquarters moved from
902-452: A crowded commuter bus or train . The term compact was coined in the 1970s by the Daily Mail , one of the earlier newspapers to make the change, although it now once again calls itself a tabloid. The purpose behind this was to avoid the association of the word tabloid with the flamboyant, salacious editorial style of the red top newspaper. The early converts from broadsheet format made
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#1732854822730984-818: A dedicated Mumbai tabloid newspaper, Mumbai Mirror , which gives prominence to Mumbai-related stories and issues. Tehelka started as a news portal in 2000. It broke the story about match-fixing in Indian and International Cricket and the sting operation on defence deals in the Indian Army. In 2007, it closed shop and reappeared in tabloid form, and has been appreciated for its brand of investigative journalism. Other popular tabloid newspapers in English media are Mid-Day , an afternoon newspaper published out of and dedicated to Mumbai and business newspapers like MINT . There are numerous tabloids in most of India's official languages. There
1066-425: A demerger and subsequent listing of the joint venture. This will create two publicly traded companies, one focusing on pharmaceuticals and research & development, the other on consumer healthcare. On 22 February 2022, GSK announced that the spin-off consumer healthcare company will be called Haleon . In January 2022, the company announced that they had received three unsolicited offers from Unilever to acquire
1148-470: A former editor of Norton's Queensland and West Australia editions of Truth took over. He would remain in the job until 1920. Norton meanwhile died of alcoholism, in 1916. The leader writer (and, briefly, editor) from 1913 to 1922 was Robert Hogg , a Scottish-born journalist and socialist. According to Yska. Hogg 'turned NZ Truth into a fiery and enthusiastic mouthpiece for revolutionary socialism'. That would change in 1922 when John Norton's son Ezra became
1230-530: A newspaper for the British Columbia market. The Canadian publisher Black Press publishes newspapers in the provinces of British Columbia and Alberta in both tabloid ( 10 + 1 ⁄ 4 in (260 mm) wide by 14 + 1 ⁄ 2 in (368 mm) deep) and what it calls "tall tab" format, where the latter is 10 + 1 ⁄ 4 in (260 mm) wide by 16 + 1 ⁄ 4 in (413 mm) deep, larger than tabloid but smaller than
1312-511: A number of tranches. The same day, the company also announced it would acquire oncology specialist, Tesaro , for US$ 5.1 billion. The deal will give GSK control of ovarian cancer treatment, Zejula - a member of the class of poly ADP ribose polymerase (PARP) inhibitors. In October 2019, GSK agreed to sell its rabies vaccine, RabAvert , and its tick-borne encephalitis vaccine, Encepur , to Bavarian Nordic for US$ 1.06 billion (€955 million). In July 2020, GSK acquired
1394-586: A primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index . As of February 2024, it had a market capitalisation of £69 billion, the eighth largest on the London Stock Exchange. The company developed the first malaria vaccine , RTS,S , which it said in 2014, it would make available for five per cent above cost. Legacy products developed at GSK include several listed in
1476-643: A single entity. The combined entity would have sales of around £9.8 billion ($ 12.7 billion), with GSK maintaining a 68% controlling stake in the joint venture. Pfizer would own the remaining 32% shareholding. The deal builds on an earlier 2018 deal where GSK bought out Novartis' stake in the GSK-Novartis consumer healthcare joint business. The culmination of the Consumer Healthcare string of deals will result in GSK splitting into two separate companies, via
1558-553: Is Bulgar , but some are written in English, like the People's Journal and Tempo . Like their common journalistic connotations, Philippine tabloids usually report sensationalist crime stories and celebrity gossip, and some tabloids feature topless photos of girls. Several tabloids are vernacular counterparts of English broadsheet newspapers by the same publisher, like Pilipino Star Ngayon ( The Philippine Star ), Bandera ( Philippine Daily Inquirer ), and Balita ( Manila Bulletin ). In
1640-696: Is a British multinational pharmaceutical and biotechnology company with headquarters in London . It was established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham, which was itself a merger of a number of pharmaceutical companies around the Smith, Kline & French firm. GSK is the tenth largest pharmaceutical company and No. 294 on the 2022 Fortune Global 500 , ranked behind other pharmaceutical companies China Resources , Sinopharm , Johnson & Johnson , Pfizer , Roche , AbbVie , Novartis , Bayer , and Merck Sharp & Dohme . The company has
1722-520: Is an all youth tabloid by the name of TILT – The ILIKE Times. In Indonesia, tabloids include Bola, GO (Gema Olahraga, defunct), Soccer (defunct), Fantasy (defunct), Buletin Sinetron (defunct), Pro TV (defunct), Citra (defunct), Genie , Bintang Indonesia (Indonesian Stars) , Nyata , Wanita Indonesia (Women of Indonesia), Cek and Ricek , and Nova . In Oman, TheWeek is a free, 48-page, all-colour, independent weekly published from Muscat in
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#17328548227301804-519: Is circulated mostly among blue-collar labourers . Compact tabloids, just like broadsheet - and Berliner -format newspapers, span the political spectrum from progressive to conservative and from capitalist to socialist . In Morocco , Maroc Soir , launched in November 2005, is published in tabloid format. In South Africa , the Bloemfontein-based daily newspaper Volksblad became
1886-472: Is largely of editorial style; both red top and compact tabloids span the width of the political spectrum from socialism to capitalist conservatism , although red-top tabloids, on account of their historically working-class target market, generally embrace populism to some degree. Red top tabloids are so named due to their tendency, in British and Commonwealth usage, to have their mastheads printed in red ink;
1968-663: Is the United States. Its US headquarters are in Philadelphia, Pennsylvania and Durham, North Carolina; its consumer-products division is in Moon Township, Pennsylvania . In July 2020, the UK government signed up for 60 million doses of a COVID-19 vaccine developed by GSK and Sanofi . It uses a recombinant protein –based technology from Sanofi and GSK's pandemic technology. The companies claimed to be able to produce one billion doses, subject to successful trials and regulatory approval, during
2050-626: The Boston Herald . US tabloids that ceased publication include Denver's Rocky Mountain News . In Australia , tabloids include The Advertiser , the Herald Sun , The Sun-Herald , The Daily Telegraph , The Courier Mail , The West Australian , The Mercury , the Hamilton Spectator , The Portland Observer , The Casterton News and The Melbourne Observer . In Argentina , one of
2132-520: The Daily Star and the Daily Mirror . Although not using red mastheads, the Daily Mail and Daily Express also use the 'tabloid journalism' model. In contrast to red-top tabloids, compacts use an editorial style more closely associated with broadsheet newspapers. In fact, most compact tabloids formerly used the broadsheet paper size, but changed to accommodate reading in tight spaces, such as on
2214-873: The New York Post , the Daily News and Newsday in New York, the San Francisco Examiner , The Bakersfield Californian and La Opinión in California , The Jersey Journal and The Trentonian in New Jersey, the Philadelphia Daily News , the Delaware County Daily Times and The Citizens' Voice , The Burlington Free Press , The Oregonian , the Chicago Sun-Times , and
2296-729: The Beecham Group . In 1859, Beecham opened its first factory in St Helens , Lancashire . By the 1960s, Beecham was extensively involved in pharmaceuticals and consumer products such as Macleans toothpaste , Lucozade and synthetic penicillin research. John K. Smith opened his first pharmacy in Philadelphia in 1830. In 1865, Mahlon Kline joined the business, which 10 years later became Smith, Kline & Co. In 1891, it merged with French, Richard and Company, and in 1929, changed its name to Smith Kline & French Laboratories as it focused more on research. Years later it bought Norden Laboratories,
2378-594: The Berliner format (2008–2013) and now adopts a compact format with 32 pages during the week and 48 pages on Saturday. In Bangladesh , the Daily Manab Zamin became the first and is now the largest circulated Bengali language tabloid in the world. In Georgia , the weekly English-language newspaper The Financial switched to a compact format in 2005 and doubled the number of pages in each issue. Other Georgian-language newspapers have tested compact formats in
2460-734: The Lucozade and Ribena brands of soft drinks, but they were sold in 2013, to Suntory for £1.35bn. Other products include Abreva to treat cold sores; Night Nurse, a cold remedy; Breathe Right nasal strips ; and Nicoderm and Nicorette nicotine replacements. In March 2014, it recalled Alli , an over-the-counter weight-loss drug, in the United States and Puerto Rico because of possible tampering, following customer complaints. As of 2013 , GSK had offices in over 115 countries and employed over 99,000 people, 12,500 in R&;D . The company's single largest market
2542-646: The Netherlands , several newspapers have started publishing tabloid versions of their newspapers, including one of the major 'quality' newspapers, NRC Handelsblad , with nrc•next (ceased 2021) in 2006. Two free tabloid newspapers were also introduced in the early 2000s, ' Metro and Sp!ts (ceased 2014), mostly for distribution in public transportation. In 2007, a third and fourth free tabloid appeared, ' De Pers ' (ceased 2012) and ' DAG ' (ceased 2008). De Telegraaf , came in broadsheet but changed to tabloid in 2014. In Norway , close to all newspapers have switched from
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2624-526: The Nice Matin (or Le Dauphiné ), a popular Southern France newspaper changed from Broadsheet to Tabloid on 8 April 2006. They changed the printing format in one day after test results showed that 74% liked the Tabloid format compared to Broadsheet. But the most famous tabloid dealing with crime stories is Le Nouveau Détective , created in the early 20th century. This weekly tabloid has a national circulation. In
2706-475: The Southern Philippines , a new weekly tabloid, The Mindanao Examiner , now includes media services, such as photography and video production, into its line as a source to finance the high cost of printing and other expenses. It is also into independent film making. The Berliner format, used by many prominent European newspapers, is sized between the tabloid and the broadsheet. In a newspaper context,
2788-727: The World Health Organization's List of Essential Medicines , such as amoxicillin , mercaptopurine , pyrimethamine and zidovudine . In 2012, under prosecution by the United States Department of Justice (DoJ) based on combined investigations of the Department of Health and Human Services (HHS-OIG), FDA and FBI , primarily concerning sales and marketing of the drugs Avandia , Paxil and Wellbutrin , GSK pleaded guilty to promotion of drugs for unapproved uses, failure to report safety data and kickbacks to physicians in
2870-442: The ' Swinging Sixties ' were already shaking apart NZ Truth's world. By 1980, circulation stood at 150,000, but a move to Auckland headquarters in 1982 and a 'brighter' Truth and TV Extra failed. By the mid 1990s, circulation fell to 50,000, and in 2005, as the once proud and powerful weekly approached its centenary, plummeted to a once unthinkable 12,000. At the end of October 2012, controversial right-wing blogger Cameron Slater
2952-485: The 1918 reference to smaller sheet newspapers that contained the condensed stories. Tabloid newspapers, especially in the United Kingdom , vary widely in their target market, political alignment, editorial style, and circulation. Thus, various terms have been coined to describe the subtypes of this versatile paper format. There are, broadly, two main types of tabloid newspaper: red top and compact . The distinction
3034-724: The Consumer Healthcare business unit, with the final proposal valuing the business unit at £50 billion (£41.7 billion in cash, plus £8.3 billion in Unilever shares). Subsequently, GSK declined all outside offers/attempts to acquire its consumer healthcare business and moved forward with its plan to complete the demerger from the main biopharmaceutical business. In April 2022, the business announced it would acquire Sierra Oncology Inc for $ 1.9 billion ($ 55 per share). In May 2022, GSK announced it would acquire Affinivax and its phase II 24-valent pneumococcal vaccine candidate for up to $ 3.3 billion, strengthening its vaccine business. On 16 May 2022,
3116-622: The FDA approved GSK's vaccine for 2009 H1N1 influenza protection, manufactured by the company's ID Biomedical Corp in Canada. Also in November 2009, GSK formed a joint venture with Pfizer to create ViiV Healthcare , which specializes in HIV research. In 2010, the company acquired Laboratorios Phoenix, an Argentine pharmaceutical company, for US$ 253m, and the UK-based sports nutrition company Maxinutrition for £162 million (US$ 256 million). In 2011, in
3198-570: The Sultanate of Oman. Oman's first free newspaper was launched in March 2003 and has now gone on to gather what is believed to be the largest readership for any publication in Oman. Ms Mohana Prabhakar is the managing editor of the publication. TheWeek is audited by BPA Worldwide, which has certified its circulation as being a weekly average of 50,300. In Pakistan, Khabrain is a tabloid newspaper popular within
3280-463: The Sydney-based owner and proprietor, appointing a string of New Zealand-based editors. Under the populist Norton, the 'worker's paper' became the streamlined family-friendly 'national paper'. Norton's most successful editor was Australian Brian Connolly and over 16 years (1935 to 1951), he would return the paper to its working-class roots, albeit with a conservative streak. In 1951, Norton sold out to
3362-617: The US headquarters until the company moved to Research Triangle Park in North Carolina in 1971. The Nobel Prize winning scientists Gertrude B. Elion and George H. Hitchings worked there and invented drugs still used many years later, such as mercaptopurine . In 1959, the Wellcome Foundation bought Cooper, McDougall & Robertson Inc to become more active in animal health. When Burroughs Wellcome decided to move its headquarters,
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3444-696: The US market. In 1983, the American arm, Glaxo Inc., moved to Research Triangle Park (US headquarters/research) and Zebulon (US manufacturing) in North Carolina . Burroughs Wellcome & Company was founded in 1880, in London by the American pharmacists Henry Wellcome and Silas Burroughs . The Wellcome Tropical Research Laboratories opened in 1902. In the 1920s, Burroughs Wellcome established research and manufacturing facilities in Tuckahoe, New York , which served as
3526-480: The United States and agreed to pay a US$ 3 billion (£1.9bn) settlement. It was the largest health-care fraud case to date in the US and the largest settlement in the pharmaceutical industry . Joseph Nathan and Co. was founded in 1873, as a general trading company in Wellington , New Zealand, by a Londoner, Joseph Edward Nathan . In 1904, it began producing a dried-milk baby food from excess milk produced on dairy farms near Bunnythorpe . The resulting product
3608-625: The United States to England. To expand R&D in the United States, the company bought a new research center in 1995; another opened in 1997, in England at New Frontiers Science Park , Harlow . Glaxo Wellcome and SmithKline Beecham announced their intention to merge in January 2000. The merger was completed on 27 December that year, forming GlaxoSmithKline (GSK). The company's global headquarters were at GSK House, Brentford , London, officially opened in 2002, by then-Prime Minister Tony Blair . The building
3690-570: The black working class. It sells over 500,000 copies per day, reaching approximately 3,000,000 readers. Besides offering a sometimes satirical view of the seriousness of mainstream news, the Daily Sun also covers fringe theories and paranormal claims such as tikoloshes , ancestral visions and all things supernatural. It is also published as the Sunday Sun . In Mauritius , the popular afternoon newspaper Le Mauricien shifted from tabloid (1908–2008) to
3772-518: The brands Lucozade and Ribena ; however, the deal did not include Horlicks . In March 2014, GSK paid US$ 1 billion to raise its stake in its Indian pharmaceutical unit, GlaxoSmithKline Pharmaceuticals , to 75 per cent as part of a move to focus on emerging markets. In April 2014, Novartis and Glaxo agreed on more than US$ 20 billion in deals, with Novartis selling its vaccine business to GSK and buying GSK's cancer business. In February 2015, GSK announced that it would acquire GlycoVaxyn,
3854-576: The broadsheet to the tabloid format, which measures 280 x 400 mm. The three biggest newspapers are Dagbladet , VG , and Aftenposten . In Poland , the newspaper Fakt , sometimes Super Express is considered as tabloid. In the United Kingdom, three previously broadsheet daily newspapers— The Times , The Scotsman and The Guardian —have switched to tabloid size in recent years, and two— Daily Express and Daily Mail —in former years, although The Times and The Scotsman call
3936-729: The broadsheets it also publishes. In the United States , daily tabloids date back to the founding of the New York Daily News in 1919, followed by the New York Daily Mirror , and the New York Evening Graphic in the 1920s. Competition among those three for crime, sex and celebrity news was considered a scandal to the mainstream press of the day. The tabloid format is used by a number of respected and indeed prize-winning American papers. Prominent U.S. tabloids include
4018-635: The business unit as they look to strengthen their presence in India. On 3 December 2018, GSK announced that Unilever would acquire the Indian-listed GlaxoSmithKline Consumer Healthcare business for US$ 3.8 billion (£2.98 billion). Unilever will pay the majority of the deal in cash, with the remaining being paid in shares in its Indian operation, Hindustan Unilever Limited . Upon completion, GSK will then own around 5.7% of Hindustan Unilever Limited, selling those shares in
4100-590: The change in the 1970s; two British papers that took this step at the time were the Daily Mail and the Daily Express . In 2003, The Independent also made the change for the same reasons, quickly followed by The Scotsman and The Times . On the other hand, The Morning Star had always used the tabloid size, but stands in contrast to both the red top papers and the former broadsheets; although The Morning Star emphasizes hard news , it embraces socialism and
4182-636: The company aligned with GSK's business. In September 2019, Avalon Ventures announced that it entered into a definitive agreement with GlaxoSmithKline (GSK) for the acquisition of Sitari Pharmaceuticals by GSK. This includes its transglutaminase 2 (TG2) small molecule program for the treatment of celiac disease . Four GlaxoSmithKline scientists have been recognized by the Nobel Committee for their contributions to basic medical science and/or therapeutics development. Since 2010, GlaxoSmithKline has several times ranked first among pharmaceutical companies on
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#17328548227304264-1308: The company changed its name from GlaxoSmithKline to GSK. In April 2023, GSK announced it would acquire Bellus Health Inc. for $ 2 billion. In February 2024, the company acquired Aiolos Bio for over $ 1 billion, adding to its existing asthma business through AIO-001 a long-acting monoclonal antibody that targets the thymic stromal lymphopoietin cytokine. In May 2024, GSK sold off its 4.2% shares in Haleon for $ 1.58 billion. In July 2024, GSK moved its headquarters from Brentford to New Oxford Street in central London. GSK manufactures products for major disease areas such as asthma, cancer, infections, diabetes, and mental health. Medicines historically discovered or developed at GSK and its legacy companies and now sold as generics include amoxicillin and amoxicillin-clavulanate , ticarcillin-clavulanate , mupirocin , and ceftazidime for bacterial infections, zidovudine for HIV infection , valacyclovir for herpes virus infections, albendazole for parasitic infections, sumatriptan for migraine , lamotrigine for epilepsy, bupropion and paroxetine for major depressive disorder , cimetidine and ranitidine for gastroesophageal reflux disorder , mercaptopurine and thioguanine for
4346-452: The company divested its portfolio of gene therapy drugs to Orchard Therapeutics in April 2018. In November 2018, Reuters reported that Unilever was in prime position to acquire GSK's interest in its Indian unit, GlaxoSmithKline Consumer Healthcare Ltd, in a sale that could generate around US$ 4 billion for the company. Nestlé and Coca-Cola have also been reported to be interested in
4428-512: The company selected Paul Rudolph to design its new building. The Elion-Hitchings Building "was celebrated worldwide when it was built," according to Paul Rudolph Heritage Foundation president Kelvin Dickinson. Alex Sayf Cummings of Georgia State University wrote in 2016, that the "iconic building helped define the image of RTP," saying, "Love it or hate it, Rudolph's design remains an impressively audacious creative gesture and an important part of
4510-444: The compressed tablets they marketed as "Tabloid" pills in the late 1880s. The connotation of tabloid was soon applied to other small compressed items. A 1902 item in London's Westminster Gazette noted, "The proprietor intends to give in tabloid form all the news printed by other journals." Thus tabloid journalism in 1901, originally meant a paper that condensed stories into a simplified, easily absorbed format. The term preceded
4592-517: The country's two main newspapers, Clarín , is a tabloid. In Brazil , many newspapers are tabloids, including sports daily Lance! (which circulates in cities such as Rio de Janeiro and São Paulo ), most publications currently and formerly owned by Grupo RBS (especially the Porto Alegre daily Zero Hora ), and, in March 2009, Rio de Janeiro-based O Dia switched to tabloid from broadsheet, though, several years later, it reverted to being
4674-496: The early 1990s. Tabloid journalism is still an evolving concept in India's print media. The first tabloid, Blitz was started by Russi Karanjia on February 1, 1941 with the words "Our Blitz, India's Blitz against Hitler !". Blitz was first published in English and then branched out with Hindi , Marathi and Urdu versions. In 1974, Russi's daughter Rita founded the Cine Blitz magazine. In 2005, Times of India brought out
4756-589: The first malaria vaccine . Malaria is responsible for over 650,000 deaths annually, mainly in Africa. Known as RTS,S , the vaccine was developed as a joint project with the PATH vaccines initiative and the Bill and Melinda Gates Foundation . The company has committed to making the vaccine available in developing countries for five per cent above the cost of production. As of 2013 , RTS,S, which uses GSK's proprietary AS01 adjuvant,
4838-496: The first half of 2021. The company also agreed to a $ 2.1 billion deal with the United States to produce 100 million doses of the vaccine. SR One was established in 1985, by SmithKline Beecham to invest in new biotechnology companies and continued operating after GSK was formed; by 2003, GSK had formed another subsidiary, GSK Ventures, to out-license or start new companies around drug candidates that it did not intend to develop further. As of 2003 , SR One tended to invest only if
4920-410: The first serious broadsheet newspaper to switch to tabloid, but only on Saturdays. Despite the format being popular with its readers, the newspaper remains broadsheet on weekdays. This is also true of Pietermaritzburg's daily, The Witness in the province of KwaZulu-Natal . The Daily Sun , published by Naspers , has since become South Africa's biggest-selling daily newspaper and is aimed primarily at
5002-582: The format " compact " to avoid the down-market connotation of the word tabloid . Similarly, when referring to the down-market tabloid newspapers the alternative term " red-top " (referring to their traditionally red-coloured mastheads) is increasingly used, to distinguish them from the up- and middle-market compact newspapers. The Morning Star also comes in tabloid format; however, it avoids celebrity stories, and instead favours issues relating to labour unions . In Canada many newspapers of Postmedia 's Sun brand are in tabloid format including The Province ,
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#17328548227305084-457: The group's structure in 1947, making Glaxo the parent and obtained a listing on the London Stock Exchange . Glaxo acquired Allen & Hanburys in 1958. The Scottish pharmacologist David Jack was hired as a researcher for Allen & Hanburys a few years after Glaxo took it over; he went on to lead the company's research and development (R&D) until 1987. After Glaxo bought Meyer Laboratories in 1978, it began to play an important role in
5166-458: The history of both architecture and Research Triangle Park ." United Therapeutics , which bought the building in 2012, announced plans in 2020, to tear it down. Glaxo and Wellcome merged in 1995, to form Glaxo Wellcome plc. The merger was then considered the biggest in the UK corporate history. Glaxo Wellcome restructured its R&D operation that year, cutting 10,000 jobs worldwide, closing its R&D facility in Beckenham, Kent, and opening
5248-425: The lower middle class. This news group introduced a new paper, Naya Akhbar which is comparably more sensational. At the local level, many sensational tabloids can be seen but, unlike Khabrain or other big national newspapers, they are distributed only on local levels in districts. Tabloids in the Philippines are usually written in local languages, like Tagalog or Bisaya , one of the listed top Tagalog tabloids
5330-400: The major daily newspapers, in that they purport to offer an "alternative" viewpoint, either in the sense that the paper's editors are more locally oriented, or that the paper is editorially independent from major media conglomerates. Other factors that distinguish "alternative" weekly tabloids from the major daily newspapers are their less-frequent publication, and that they are usually free to
5412-477: The newspapers will draw their advertising revenue from different types of businesses or services. An upmarket weekly's advertisers are often organic grocers, boutiques, and theatre companies while a downmarket's may have those of trade schools, supermarkets, and the sex industry. Both usually contain ads from local bars, auto dealers, movie theaters, and a classified ads section. GlaxoSmithKline GSK plc (an acronym from its former name GlaxoSmithKline plc )
5494-435: The personal lives of celebrities and sports stars, and junk food news . Celebrity gossip columns which appear in red top tabloids and focus on their sexual practices , misuse of narcotics , and the private aspects of their lives often border on, and sometimes cross the line of defamation . Red tops tend to be written with a simplistic, straightforward vocabulary and grammar; their layout usually gives greater prominence to
5576-460: The picture than to the word. The writing style of red top tabloids is often accused of sensationalism and extreme political bias; red tops have been accused of deliberately igniting controversy and selectively reporting on attention-grabbing stories, or those with shock value . In the extreme case, tabloids have been accused of lying or misrepresenting the truth to increase circulation. Examples of British red top newspapers include The Sun ,
5658-468: The term Berliner is generally used only to describe size, not to refer to other qualities of the publication. The biggest tabloid (and newspaper in general) in Europe, by circulation, is Germany's Bild , with around 2.5 million copies (down from above 5 million in the 1980s). Although its paper size is bigger, its style was copied from the British tabloids. In Denmark , tabloids in the British sense are known as 'formiddagsblade' (before-noon newspapers),
5740-445: The term compact was coined to avoid the connotation of the word tabloid , which implies a red top tabloid, and has lent its name to tabloid journalism , which is journalism after the fashion of red top reporters. Red top tabloids, named after their distinguishing red mastheads , employ a form of writing known as tabloid journalism ; this style emphasizes features such as sensational crime stories, astrology, gossip columns about
5822-421: The treatment of leukemia, allopurinol for gout , pyrimethamine for malaria , and the antibacterial trimethoprim . Among these, albendazole, amoxicillin, amoxicillin-clavulanate, allopurinol, mercaptopurine, mupirocin, pyrimethamine, ranitidine, thioguanine, trimethoprim, and zidovudine are on the World Health Organization's List of Essential Medicines . In 2014, GSK applied for regulatory approval for
5904-455: The treatment of migraine), salbutamol (Ventolin) (for the treatment of asthma), Zovirax (for the treatment of coldsores), and Retrovir and Epivir (for the treatment of AIDS). In 1999, the company was the world's largest manufacturer of drugs for the treatment of asthma and HIV/AIDS. It employed 59,000 people, including 13,400 in the UK, had 76 operating companies and 50 manufacturing facilities worldwide, and seven of its products were among
5986-503: The two biggest being BT and Ekstra Bladet . The old more serious newspaper Berlingske Tidende shifted from broadsheet to tabloid format in 2006, while keeping the news profile intact. In Finland , the biggest newspaper and biggest daily subscription newspaper in the Nordic countries Helsingin Sanomat changed its size from broadsheet to tabloid on 8 January 2013. In France ,
6068-487: The user, since they rely on ad revenue. Alternative weekly tabloids may concentrate on local and neighbourhood-level issues, and on entertainment in bars, theatres, or other such venues. Alternative tabloids can be positioned as upmarket (quality) newspapers, to appeal to the better-educated, higher-income sector of the market; as middle-market (popular); or as downmarket (sensational) newspapers, which emphasize sensational crime stories and celebrity gossip. In each case,
6150-562: The world's top 50 best-selling pharmaceuticals. The company had R&D facilities in Hertfordshire, Kent , London and Verona (Italy), and manufacturing plants in Scotland and the north of England. It had R&D centres in the US and Japan, and production facilities in the US, Europe and the Far East. In 1848, Thomas Beecham launched his Beecham's Pills laxative in England, giving birth to
6232-445: Was "too far gone". Despite ceasing to publish a print version of the website, the publication continued to update its website until May 2014. Tabloid (newspaper format) A tabloid is a newspaper with a compact page size smaller than broadsheet . There is no standard size for this newspaper format . The word tabloid comes from the name given by the London -based pharmaceutical company Burroughs Wellcome & Co. to
6314-523: Was 'a combustible mix of tycoon, journalist, do-gooder and chronic, falldown pisshead.' Norton was on hand on 24 June 1905 when the first copies of the 'Maoriland' edition rolled off the presses in Luke's Lane, an alley that still runs at right angles to Wellington's Courtenay Place . Inaugural editor, Australian Robert Merrick, claimed 40,000 readers by 1907, with circulation in 'every Miners', Gum Diggers' and Timber-Getter's camp'. Three years later Frederick Dawson,
6396-452: Was announced as the paper's new editor. He said in his new role he would be "kicking arse and sticking up for the little guy". His first issue was published that November. As a result of his appointment, the paper's left-wing columnist Martyn "Bomber" Bradbury quit. Within six months of Slater's appointment it was announced the publication would cease production in July 2013, with Slater claiming it
6478-569: Was appointed chairman of the board in 2005. GSK opened its first R&D centre in China in 2007, in Shanghai, initially focused on neurodegenerative diseases. Andrew Witty became the chief executive officer in 2008. Witty joined Glaxo in 1985, and had been president of GSK's Pharmaceuticals Europe since 2003. In 2009, GSK acquired Stiefel Laboratories , then the world's largest independent dermatology drug company, for US$ 3.6 billion . In November 2009,
6560-756: Was being examined in a Phase 3 trial in eight African countries. PATH reported that "[i]n the 12-month period following vaccination, RTS,S conferred approximately 50% protection from clinical Plasmodium falciparum disease in children aged 5-17 months, and approximately 30% protection in children aged 6-12 weeks when administered in conjunction with Expanded Program for Immunization (EPI) vaccines." In 2014, Glaxo said it had spent more than US$ 350 million and expected to spend an additional US$ 260 million before seeking regulatory approval. GSK's consumer healthcare division, which earned £5.2 billion in 2013, sells oral healthcare, including Aquafresh , Macleans and Sensodyne toothpastes. GSK also previously owned
6642-493: Was erected at a cost of £300 million and as of 2002 was home to 3,000 administrative staff. GSK completed the acquisition of New Jersey–based Block Drug in 2001, for US$ 1.24 billion . In 2006, GSK acquired the US-based consumer healthcare company CNS Inc., whose products included Breathe Right nasal strips and FiberChoice dietary supplements, for US$ 566 million in cash. Chris Gent , previously CEO of Vodafone ,
6724-441: Was first known as Defiance, then as Glaxo (from lacto ), and sold with the slogan "Glaxo builds bonnie babies." The Glaxo Laboratories sign is still visible on what is now a car repair shop on the main street of Bunnythorpe. The company's first pharmaceutical product, released in 1924, was vitamin D. Glaxo Laboratories was incorporated as a distinct subsidiary company in London in 1935. Joseph Nathan's shareholders reorganised
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