Misplaced Pages

Formulary (pharmacy)

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.

A formulary is a list of pharmaceutical drugs , often decided upon by a group of people, for various reasons such as insurance coverage or use at a medical facility. Traditionally, a formulary contained a collection of formulas for the compounding and testing of medication (a resource closer to what would be referred to as a pharmacopoeia today). Today, the main function of a prescription formulary is to specify particular medications that are approved to be prescribed at a particular hospital , in a particular health system , or under a particular health insurance policy. The development of prescription formularies is based on evaluations of efficacy, safety, and cost-effectiveness of drugs.

#471528

79-542: Depending on the individual formulary, it may also contain additional clinical information, such as side effects , contraindications , and doses . By the turn of the millennium, 156 countries had national or provincial essential medicines lists and 135 countries had national treatment. In Australia, where there is a public health care system, medications are subsidised under the Pharmaceutical Benefits Scheme (PBS) and medications that are available under

158-647: A Middle English quotation making this contrast, from as early as 1400: "O Lord, whi is it so greet difference betwixe a cirugian and a physician." Henry VIII granted a charter to the London Royal College of Physicians in 1518. It was not until 1540 that he granted the Company of Barber-Surgeons (ancestor of the Royal College of Surgeons ) its separate charter. In the same year, the English monarch established

237-407: A disease or procedure and negatively affect its prognosis . They may also lead to non-compliance with a treatment regimen. Adverse effects of medical treatment resulted in 142,000 deaths in 2013 up from 94,000 deaths in 1990 globally. The harmful outcome is usually indicated by some result such as morbidity , mortality , alteration in body weight , levels of enzymes , loss of function, or as

316-451: A pathological change detected at the microscopic, macroscopic or physiological level. It may also be indicated by symptoms reported by a patient. Adverse effects may cause a reversible or irreversible change, including an increase or decrease in the susceptibility of the individual to other chemicals, foods , or procedures, such as drug interactions . In terms of drugs, adverse events may be defined as: "Any untoward medical occurrence in

395-471: A "College of Physicians and Surgeons". All American states have an agency that is usually called the "Medical Board", although there are alternate names such as "Board of Medicine", "Board of Medical Examiners", "Board of Medical Licensure", "Board of Healing Arts" or some other variation. After graduating from a first-professional school, physicians who wish to practice in the US usually take standardized exams, such as

474-496: A DPM degree. After residency, one to two years of fellowship programs are available in plastic surgery, foot and ankle reconstructive surgery, sports medicine, and wound care. Podiatry residencies and/ or fellowships are not accredited by the ACGME . The overall scope of podiatric practice varies from state to state and is not similar to that of physicians holding an MD or DO degree. DPM is also available at one Canadian university, namely

553-451: A basic medical qualification, and up to another nine years to become a specialist. In most jurisdictions, physicians (in either sense of the word) need government permission to practice. Such permission is intended to promote public safety, and often to protect government spending, as medical care is commonly subsidized by national governments. In some jurisdictions such as in Singapore , it

632-714: A beneficial effect on their health and lifestyle. According to a study of male physicians in the United States, life expectancy is slightly higher for physicians (73 years for white and 69 years for black) than lawyers or many other highly educated professionals. Causes of death which are less likely to occur in physicians than the general population include respiratory disease (including pneumonia , pneumoconioses , COPD , but excluding emphysema and other chronic airway obstruction ), alcohol-related deaths, rectosigmoid and anal cancers , and bacterial diseases. Physicians do experience exposure to occupational hazards , and there

711-456: A collateral or side effect of many interventions, but they are particularly important in pharmacology , due to its wider, and sometimes uncontrollable, use by way of self-medication . Thus, responsible drug use becomes an important issue here. Adverse effects, like therapeutic effects of drugs, are a function of dosage or drug levels at the target organs , so they may be avoided or decreased by means of careful and precise pharmacokinetics ,

790-531: A compromise must be found by the physician and the patient between the beneficial or life-saving consequences of surgery versus its adverse effects. For example, a limb may be lost to amputation in case of untreatable gangrene , but the patient's life is saved. Presently, one of the greatest advantages of minimally invasive surgery, such as laparoscopic surgery , is the reduction of adverse effects. Other nonsurgical physical procedures, such as high-intensity radiation therapy , may cause burns and alterations in

869-570: A detailed knowledge of the academic disciplines , such as anatomy and physiology , underlying diseases , and their treatment, which is the science of medicine, and a decent competence in its applied practice, which is the art or craft of the profession. Both the role of the physician and the meaning of the word itself vary around the world. Degrees and other qualifications vary widely, but there are some common elements, such as medical ethics requiring that physicians show consideration, compassion, and benevolence for their patients . Around

SECTION 10

#1732852559472

948-542: A feeling of decreased personal achievement, and others. A study by the Agency for Healthcare Research and Quality reported that time pressure was the greatest cause of burnout; a survey from the American Medical Association reported that more than half of all respondents chose "too many bureaucratic tasks" as the leading cause of burnout. Medical education and career pathways for doctors vary considerably across

1027-582: A form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all. The Medication Appropriateness Tool for Comorbid Health Conditions in Dementia ( MATCH-D ) warns that people with dementia are more likely to experience adverse effects, and that they are less likely to be able to reliably report symptoms. Sometimes, putative medical adverse effects are regarded as controversial and generate heated discussions in society and lawsuits against drug manufacturers. One example

1106-464: A patient or clinical investigation subject administered a pharmaceutical product and which does not necessarily have to have a causal relationship with this treatment." In clinical trials , a distinction is made between an adverse event and a serious adverse event . Generally, any event which causes death, permanent damage, birth defects , or requires hospitalization is considered a serious adverse event. The results of trials are often included in

1185-418: A physician, in the broad sense). In Commonwealth countries, specialist pediatricians and geriatricians are also described as specialist physicians who have sub-specialized by age of patient rather than by organ system. Around the world, the combined term "physician and surgeon" is used to describe either a general practitioner or any medical practitioner irrespective of specialty. This usage still shows

1264-412: A reduction in blood levels of drugs they are taking for other purposes, such as cancer chemotherapeutic drugs, protease inhibitors for HIV and hormonal contraceptives . The scientific field of activity associated with drug safety is increasingly government-regulated, and is of major concern for the public, as well as to drug manufacturers . The distinction between adverse and nonadverse effects

1343-413: A severe nature, such as breast cancer , have led to public outcry and changes in medical therapy, although its benefits largely surpassed the statistical risks. Physicians A physician , medical practitioner ( British English ), medical doctor , or simply doctor is a health professional who practices medicine , which is concerned with promoting, maintaining or restoring health through

1422-430: A severe, sometimes fatal complication which may result in persons who have eczema or atopic dermatitis . Diagnostic procedures may also have adverse effects, depending much on whether they are invasive , minimally invasive or noninvasive . For example, allergic reactions to radiocontrast materials often occur, and a colonoscopy may cause the perforation of the intestinal wall. Adverse effects can occur as

1501-455: A significant cultural content, including conventional western medicine. Ayurveda , Unani medicine , and homeopathy are popular types of alternative medicine. Some commentators have argued that physicians have duties to serve as role models for the general public in matters of health, for example by not smoking cigarettes. Indeed, in most western nations relatively few physicians smoke, and their professional knowledge does appear to have

1580-435: A significant number of deaths, causing the forced or voluntary withdrawal of the drug from the market. Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects, which have a widely variable incidence according to individual sensitivity, include nausea , dizziness , diarrhea , malaise , vomiting , headache , dermatitis , dry mouth, etc. These can be considered

1659-465: A subset of the more comprehensive BNF. These formularies are not absolutely binding, and physicians may prescribe a non-formulary medicine if they consider it necessary and justifiable. Often, these local formularies are shared between a Primary Care Organisation (PCO) and hospitals within that PCO's jurisdiction, in order to facilitate the procedure of transferring a patient from primary care to secondary care , thus causing fewer "interfacing" issues in

SECTION 20

#1732852559472

1738-595: A therapy. Part of the difficulty is identifying the source of a complaint. A headache in a patient taking medication for influenza may be caused by the underlying disease or may be an adverse effect of the treatment. In patients with end-stage cancer , death is a very likely outcome and whether the drug is the cause or a bystander is often difficult to discern. Surgery may have a number of undesirable or harmful effects, such as infection , hemorrhage , inflammation , scarring , loss of function, or changes in local blood flow . They can be reversible or irreversible, and

1817-482: A three- or four-year degree, often in science) are usually four or five years in length. Hence, gaining a basic medical degree may typically take from five to eight years, depending on jurisdiction and university. Following the completion of entry-level training, newly graduated medical practitioners are often required to undertake a period of supervised practice before full registration is granted, typically one or two years. This may be referred to as an " internship ", as

1896-489: A tiered formulary provides financial incentives for patients to select lower-cost drugs. For example, under a 3-tier formulary, the first tier typically includes generic drugs with the lowest cost sharing (e.g., 10% coinsurance), the second includes preferred brand-name drugs with higher cost sharing (e.g., 25%), and the third includes non-preferred brand-name drugs with the highest cost-sharing (e.g., 40%). When used appropriately, formularies can help manage drug costs imposed on

1975-514: A variety of care and are therefore also referred to as general practitioners . Family medicine grew out of the general practitioner movement of the 1960s in response to the growing specialization in medicine that was seen as threatening to the doctor-patient relationship and continuity of care. In the United States, the American Podiatric Medical Association (APMA) defines podiatrists as physicians and surgeons who treat

2054-401: Is evidence-based medicine . Within conventional medicine, most physicians still pay heed to their ancient traditions: The critical sense and sceptical attitude of the citation of medicine from the shackles of priestcraft and of caste; secondly , the conception of medicine as an art based on accurate observation, and as a science, an integral part of the science of man and of nature; thirdly ,

2133-756: Is a major undertaking when a new drug is developed and tested before marketing it. This is done in toxicity studies to determine the nonadverse effect level (NOAEL). These studies are used to define the dosage to be used in human testing (phase I), as well as to calculate the maximum admissible daily intake. Imperfections in clinical trials, such as insufficient number of patients or short duration, sometimes lead to public health disasters, such as those of fenfluramine (the so-called fen-phen episode), thalidomide and, more recently, of cerivastatin (Baycol, Lipobay) and rofecoxib (Vioxx), where drastic adverse effects were observed, such as teratogenesis , pulmonary hypertension , stroke , heart disease , neuropathy , and

2212-467: Is a well-known aphorism that "doctors make the worst patients". Causes of death that are shown to be higher in the physician population include suicide among doctors and self-inflicted injury , drug-related causes, traffic accidents, and cerebrovascular and ischaemic heart disease. Physicians are also prone to occupational burnout . This manifests as a long-term stress reaction characterized by poorer quality of care towards patients, emotional exhaustion,

2291-812: Is an important component of New Zealand's pharmacovigilance activities. The Centre for Adverse Reactions Monitoring (CARM) in Dunedin is New Zealand's national monitoring centre for adverse reactions. It collects and evaluates spontaneous reports of adverse reactions to medicines, vaccines, herbal products and dietary supplements from health professionals in New Zealand. Currently the CARM database holds over 80,000 reports and provides New Zealand-specific information on adverse reactions to these products, and serves to support clinical decision making when unusual symptoms are thought to be therapy related In Canada, adverse reaction reporting

2370-663: Is an important component of the surveillance of marketed health products conducted by the Health Products and Food Branch (HPFB) of Health Canada. Within HPFB, the Marketed Health Products Directorate leads the coordination and implementation of consistent monitoring practices with regards to assessment of signals and safety trends, and risk communications concerning regulated marketed health products. MHPD also works closely with international organizations to facilitate

2449-477: Is an undesired harmful effect resulting from a medication or other intervention , such as surgery . An adverse effect may be termed a " side effect ", when judged to be secondary to a main or therapeutic effect . The term complication is similar to adverse effect, but the latter is typically used in pharmacological contexts, or when the negative effect is expected or common. If the negative effect results from an unsuitable or incorrect dosage or procedure, this

Formulary (pharmacy) - Misplaced Pages Continue

2528-469: Is begun immediately following completion of entry-level training, or even before. In other jurisdictions, junior medical doctors must undertake generalist (un-streamed) training for one or more years before commencing specialization. Hence, depending on the jurisdiction, a specialist physician (internist) often does not achieve recognition as a specialist until twelve or more years after commencing basic medical training—five to eight years at university to obtain

2607-415: Is called a medical error and not an adverse effect. Adverse effects are sometimes referred to as " iatrogenic " because they are generated by a physician /treatment. Some adverse effects occur only when starting, increasing or discontinuing a treatment. Using a drug or other medical intervention which is contraindicated may increase the risk of adverse effects. Adverse effects may cause complications of

2686-531: Is common for physicians to inflate their qualifications with the title "Dr" in correspondence or namecards, even if their qualifications are limited to a basic (e.g., bachelor level) degree. In other countries such as Germany , only physicians holding an academic doctorate may call themselves doctor – on the other hand, the European Research Council has decided that the German medical doctorate does not meet

2765-546: Is common in most of the world including the United Kingdom and other Commonwealth countries (such as Australia , Bangladesh , India , New Zealand , Pakistan , South Africa , Sri Lanka , and Zimbabwe ), as well as in places as diverse as Brazil , Hong Kong , Indonesia , Japan , Ireland , and Taiwan . In such places, the more general English terms doctor or medical practitioner are prevalent, describing any practitioner of medicine (whom an American would likely call

2844-457: Is often termed biomedicine by medical anthropologists . Biomedicine "formulates the human body and disease in a culturally distinctive pattern", and is a world view learnt by medical students. Within this tradition, the medical model is a term for the complete "set of procedures in which all doctors are trained", including mental attitudes. A particularly clear expression of this world view, currently dominant among conventional physicians,

2923-455: Is partly from their extensive training requirements, and also because of their occupation's special ethical and legal duties. The term traditionally used by physicians to describe a person seeking their help is the word patient (although one who visits a physician for a routine check-up may also be so described). This word patient is an ancient reminder of medical duty, as it originally meant 'one who suffers'. The English noun comes from

3002-547: Is the advisory body that evaluates new medical technologies and prescription medication. Based on recommendations the provincial and territorial governments decide whether or not to implement changes to their healthcare system and public drug formularies. Provincial and territorial government provide partial prescription drug coverage and the overall drug payment is a mix of public taxation, private insurance and out-of-pocket expenses. Insurance coverage differs regionally, although each public drug coverage plan must meet standards set by

3081-607: Is the potential adverse effects of silicone breast implants , which led to class actions brought by tens of thousands of plaintiffs against manufacturers of gel-based implants, due to allegations of damage to the immune system which have not yet been conclusively proven. In 1998, Dow Corning settled its remaining suits for $ 3.2 Billion and went into bankruptcy. Due to the exceedingly high impact on public health of widely used medications, such as hormonal contraception and hormone replacement therapy , which may affect millions of users, even marginal probabilities of adverse effects of

3160-479: Is the recent controversy as to whether autism was linked to the MMR vaccine (or to thiomersal , a mercury -based preservative used in some vaccines ). No link has been found in several large studies, and despite removal of thimerosal from most early childhood vaccines beginning with those manufactured in 2003, the rate of autism has not decreased as would be expected if it had been the causative agent. Another instance

3239-499: Is the result of history and is often confusing. These meanings and variations are explained below. In the United States and Canada, the term physician describes all medical practitioners holding a professional medical degree. The American Medical Association , established in 1847, as well as the American Osteopathic Association , founded in 1897, both currently use the term physician to describe members. However,

Formulary (pharmacy) - Misplaced Pages Continue

3318-529: Is voluntary, and ADRAC requests healthcare professionals to report all adverse reactions to its current drugs of interest, and serious adverse reactions to any drug. ADRAC publishes the Australian Adverse Drug Reactions Bulletin every two months. The Government's Quality Use of Medicines program is tasked with acting on this reporting to reduce and minimize the number of preventable adverse effects each year. Adverse reaction reporting

3397-511: The Université du Québec à Trois-Rivières ; students are typically required to complete an internship in New York prior to obtaining their professional degree. The World Directory of Medical Schools does not list US or Canadian schools of podiatric medicine as medical schools and only lists US-granted MD, DO, and Canadian MD programs as medical schools for the respective regions. Many countries in

3476-536: The American College of Physicians or the Royal College of Physicians in the United Kingdom, and such hard-won membership is itself a mark of status. While contemporary biomedicine has distanced itself from its ancient roots in religion and magic, many forms of traditional medicine and alternative medicine continue to espouse vitalism in various guises: "As long as life had its own secret properties, it

3555-492: The American College of Physicians , established in 1915, does not: its title uses physician in its original sense. The vast majority of physicians trained in the United States have a Doctor of Medicine degree, and use the initials M.D. A smaller number attend osteopathic medical schools and have a Doctor of Osteopathic Medicine degree and use the initials D.O. The World Directory of Medical Schools lists both MD and DO granting schools as medical schools located in

3634-517: The Latin word patiens , the present participle of the deponent verb , patior , meaning 'I am suffering', and akin to the Greek verb πάσχειν ( romanized : paschein , lit. to suffer) and its cognate noun πάθος ( pathos , suffering). Physicians in the original, narrow sense (specialist physicians or internists, see above) are commonly members or fellows of professional organizations, such as

3713-862: The Regius Professorship of Physic at the University of Cambridge . Newer universities would probably describe such an academic as a professor of internal medicine . Hence, in the 16th century, physic meant roughly what internal medicine does now. Currently, a specialist physician in the United States may be described as an internist . Another term, hospitalist , was introduced in 1996, to describe US specialists in internal medicine who work largely or exclusively in hospitals. Such 'hospitalists' now make up about 19% of all US general internists , who are often called general physicians in Commonwealth countries. This original use, as distinct from surgeon,

3792-730: The USMLE for a Doctor in Medicine. Most countries have some method of officially recognizing specialist qualifications in all branches of medicine, including internal medicine. Sometimes, this aims to promote public safety by restricting the use of hazardous treatments. Other reasons for regulating specialists may include standardization of recognition for hospital employment and restriction on which practitioners are entitled to receive higher insurance payments for specialist services. The issue of medical errors , drug abuse, and other issues in physician professional behavior received significant attention across

3871-437: The skin . In general, these therapies try to avoid damage to healthy tissues while maximizing the therapeutic effect. Vaccination may have adverse effects due to the nature of its biological preparation, sometimes using attenuated pathogens and toxins . Common adverse effects may be fever , malaise and local reactions in the vaccination site. Very rarely, there is a serious adverse effect, such as eczema vaccinatum ,

3950-464: The study , diagnosis , prognosis and treatment of disease , injury , and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities —or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice . Medical practice properly requires both

4029-548: The "foundation" years in the UK, or as "conditional registration". Some jurisdictions, including the United States, require residencies for practice. Medical practitioners hold a medical degree specific to the university from which they graduated. This degree qualifies the medical practitioner to become licensed or registered under the laws of that particular country, and sometimes of several countries, subject to requirements for an internship or conditional registration. Specialty training

SECTION 50

#1732852559472

4108-774: The Manufacturer and User Facility Device Experience Database (MAUDE) and the Special Nutritionals Adverse Event Monitoring System. MedWatch is the main reporting center, operated by the Food and Drug Administration . In Australia ,adverse effect reporting is administered by the Adverse Drug Reactions Advisory Committee (ADRAC), a subcommittee of the Australian Drug Evaluation Committee (ADEC). Reporting

4187-553: The NHS and must be paid for privately by the patient. Recommendations for additions to the NHS formulary are provided by the National Institute for Health and Care Excellence . In addition to this, local NHS hospital trusts and Primary Care ( General Practitioners ) Clinical Commissioning Groups (CCGs), produce their own lists of medicines deemed preferable for prescribing within their locality or organisation; such lists are usually

4266-544: The Order of Physicians to practice medicine. In some countries, including the United Kingdom and Ireland, the profession largely regulates itself, with the government affirming the regulating body's authority. The best-known example of this is probably the General Medical Council of Britain. In all countries, the regulating authorities will revoke permission to practice in cases of malpractice or serious misconduct. In

4345-688: The PBS and the indications for which they can be obtained under said scheme can be found in at least two places, the PBS webpage and the Australian Medicines Handbook . The Prescription Drug List is the national formulary that lists all medical ingredients for human and animal use available with a prescription with the exception of those under the Controlled Drugs and Substances Act . The Canadian Agency for Drugs and Technologies in Health (CADTH)

4424-713: The UK, the National Health Service (NHS) provides publicly funded universal health care , financed by national health insurance . Here, formularies exist to specify which drugs are available on the NHS. The two main reference sources providing this information are the British National Formulary ( BNF ) and the Drug Tariff . There is a section in the Drug Tariff, known unofficially as the " Blacklist ", detailing medicines which are not to be prescribed under

4503-502: The US state-level depend upon continuing education to maintain competence. Through the utilization of the National Practitioner Data Bank , Federation of State Medical Boards ' disciplinary report, and American Medical Association Physician Profile Service, the 67 State Medical Boards continually self-report any adverse/disciplinary actions taken against a licensed physician in order that the other Medical Boards in which

4582-595: The United States. After completion of medical school , physicians complete a residency in the specialty in which they will practice. Subspecialties require the completion of a fellowship after residency. Both MD and DO physicians participate in the National Resident Matching Program (NRMP) and attend ACGME -accredited residencies and fellowships across all medical specialties to obtain licensure. All boards of certification now require that physicians demonstrate, by examination, continuing mastery of

4661-480: The change of drug levels in the organism in function of time after administration. Adverse effects may also be caused by drug interaction . This often occurs when patients fail to inform their physician and pharmacist of all the medications they are taking, including herbal and dietary supplements. The new medication may interact agonistically or antagonistically (potentiate or decrease the intended therapeutic effect), causing significant morbidity and mortality around

4740-536: The core knowledge and skills for a chosen specialty. Recertification varies by particular specialty between every seven and every ten years. Primary care physicians guide patients in preventing disease and detecting health problems early while they are still treatable. They are divided into two types: family medicine doctors and internal medicine doctors. Family doctors, or family physicians, are trained to care for patients of any age, while internists are trained to care for adults. Family doctors receive training in

4819-564: The counter from a supermarket. The scheme also includes all herbal supplements and unlicensed medicines found in cosmetic treatments. Adverse drug reactions (ADRs) can be reported by a number of health care professionals including physicians , pharmacists and nurses , as well as patients . In the United States several reporting systems have been built, such as the Vaccine Adverse Event Reporting System (VAERS),

SECTION 60

#1732852559472

4898-517: The developing world have the problem of too few physicians. In 2015, the Association of American Medical Colleges warned that the US will face a doctor shortage of as many as 90,000 by 2025. Within Western culture and over recent centuries, medicine has become increasingly based on scientific reductionism and materialism . This style of medicine is now dominant throughout the industrialized world, and

4977-422: The federal government. Regional health authorities are in charge of regulating and providing its residents insurance while the federal government provides insurance for specifically eligible veterans, First Nations , Inuit , Canadian Forces, federal inmates and some refugees. In the US, where a system of quasi-private healthcare is in place, a formulary is a list of prescription drugs available to enrollees, and

5056-503: The foot, ankle, and associated structures of the leg. Podiatrists undergo training with the Doctor of Podiatric Medicine (DPM) degree. The American Medical Association (AMA), however, advocates for the definition of a physician as "an individual possessing degree of either a Doctor of Medicine or Doctor of Osteopathic Medicine ." In the US, podiatrists are required to complete three to four years of podiatry residency upon graduating with

5135-597: The high moral ideals, expressed in that most "memorable of human documents" (Gomperz), the Hippocratic oath ; and fourthly , the conception and realization of medicine as the profession of a cultivated gentleman. In this Western tradition, physicians are considered to be members of a learned profession , and enjoy high social status , often combined with expectations of a high and stable income and job security . However, medical practitioners often work long and inflexible hours, with shifts at unsociable times. Their high status

5214-541: The insurance policy. However, for drugs that are not on formulary, patients must pay a larger percentage of the cost of the drug, sometimes 100%. Formularies vary between drug plans and differ in the breadth of drugs covered and costs of co-pay and premiums . Most formularies cover at least one drug in each drug class, and encourage generic substitution (also known as a preferred drug list ). Formularies have shown to cause issues in hospitals when patients are discharged when not aligned with outpatient drug insurance plans. In

5293-808: The international standards of a PhD research degree. Among the English-speaking countries, this process is known either as licensure as in the United States, or as registration in the United Kingdom , other Commonwealth countries, and Ireland . Synonyms in use elsewhere include colegiación in Spain , ishi menkyo in Japan , autorisasjon in Norway , Approbation in Germany , and άδεια εργασίας in Greece. In France , Italy and Portugal , civilian physicians must be members of

5372-486: The labelling of the medication to provide information both for patients and the prescribing physicians. The term "life-threatening" in the context of a serious adverse event refers to an event in which the patient was at risk of death at the time of the event; it does not refer to an event which hypothetically might have caused death if it were more severe. In many countries, adverse effects are required by law to be reported, researched in clinical trials and included into

5451-496: The large English-speaking federations ( United States , Canada , Australia ), the licensing or registration of medical practitioners is done at a state or provincial level, or nationally as in New Zealand. Australian states usually have a "Medical Board", which has now been replaced by the Australian Health Practitioner Regulation Agency (AHPRA) in most states, while Canadian provinces usually have

5530-466: The original meaning of physician and preserves the old difference between a physician, as a practitioner of physic , and a surgeon. The term may be used by state medical boards in the United States, and by equivalent bodies in Canadian provinces, to describe any medical practitioner. In modern English, the term physician is used in two main ways, with relatively broad and narrow meanings respectively. This

5609-550: The overemphasis on benefit, scholars have called for more complete reporting of harm from clinical trials. The Yellow Card Scheme is a United Kingdom initiative run by the Medicines and Healthcare products Regulatory Agency (MHRA) and the Commission on Human Medicines (CHM) to gather information on adverse effects to medicines . This includes all licensed medicines, from medicines issued on prescription to medicines bought over

5688-534: The patient information accompanying medical devices and drugs for sale to the public. Investigators in human clinical trials are obligated to report these events in clinical study reports . Research suggests that these events are often inadequately reported in publicly available reports. Because of the lack of these data and uncertainty about methods for synthesising them, individuals conducting systematic reviews and meta-analyses of therapeutic interventions often unknowingly overemphasise health benefit. To balance

5767-686: The process. As in the United States, the NHS actively encourages prescribing of generic drugs, in order to save more of the budget allocated to them by the Department of Health . A national formulary contains a list of medicines that are approved for prescription throughout the country, indicating which products are interchangeable. It includes key information on the composition, description, selection, prescribing, dispensing and administration of medicines. Those drugs considered less suitable for prescribing are clearly identified. Examples of national formularies are: Adverse effect An adverse effect

5846-522: The sharing of information. Adverse reaction reporting is mandatory for the industry and voluntary for consumers and health professionals. In principle, medical professionals are required to report all adverse effects related to a specific form of therapy. In practice, it is at the discretion of the professional to determine whether a medical event is at all related to the therapy. As a result, routine adverse effects reporting often may not include long-term and subtle effects that may ultimately be attributed to

5925-418: The world, in particular following a critical 2000 report which "arguably launched" the patient-safety movement. In the US, as of 2006 there were few organizations that systematically monitored performance. In the US, only the Department of Veterans Affairs randomly drug tests physicians, in contrast to drug testing practices for other professions that have a major impact on public welfare. Licensing boards at

6004-576: The world, the term physician refers to a specialist in internal medicine or one of its many sub-specialties (especially as opposed to a specialist in surgery ). This meaning of physician conveys a sense of expertise in treatment by drugs or medications, rather than by the procedures of surgeons . This term is at least nine hundred years old in English: physicians and surgeons were once members of separate professions, and traditionally were rivals. The Shorter Oxford English Dictionary , third edition, gives

6083-439: The world. In all developed countries, entry-level medical education programs are tertiary -level courses , undertaken at a medical school attached to a university . Depending on jurisdiction and university, entry may follow directly from secondary school or require pre-requisite undergraduate education . The former commonly takes five or six years to complete. Programs that require previous undergraduate education (typically

6162-454: The world. Drug-drug and food-drug interactions may occur, and so-called "natural drugs" used in alternative medicine can have dangerous adverse effects. For example, extracts of St John's wort ( Hypericum perforatum ), a phytotherapic used for treating mild depression are known to cause an increase in the cytochrome P450 enzymes responsible for the metabolism and elimination of many drugs, so patients taking it are likely to experience

6241-757: Was possible to have sciences and medicines based on those properties". The US National Center for Complementary and Alternative Medicine (NCCAM) classifies complementary and alternative medicine therapies into five categories or domains, including: alternative medical systems, or complete systems of therapy and practice; mind-body interventions, or techniques designed to facilitate the mind's effect on bodily functions and symptoms; biologically based systems including herbalism ; and manipulative and body-based methods such as chiropractic and massage therapy. In considering these alternate traditions that differ from biomedicine (see above), medical anthropologists emphasize that all ways of thinking about health and disease have

#471528