3-2147: 1A00 , 1A01 , 1A0U , 1A0Z , 1A3N , 1A3O , 1A9W , 1ABW , 1ABY , 1AJ9 , 1B86 , 1BAB , 1BBB , 1BIJ , 1BUW , 1BZ0 , 1BZ1 , 1BZZ , 1C7B , 1C7C , 1C7D , 1CLS , 1CMY , 1COH , 1DKE , 1DXT , 1DXU , 1DXV , 1FDH , 1FN3 , 1G9V , 1GBU , 1GBV , 1GLI , 1GZX , 1HAB , 1HAC , 1HBA , 1HBB , 1HBS , 1HCO , 1HDB , 1HGA , 1HGB , 1HGC , 1HHO , 1IRD , 1J3Y , 1J3Z , 1J40 , 1J41 , 1J7S , 1J7W , 1J7Y , 1JY7 , 1K0Y , 1K1K , 1KD2 , 1LFL , 1LFQ , 1LFT , 1LFV , 1LFY , 1LFZ , 1LJW , 1M9P , 1MKO , 1NEJ , 1NIH , 1NQP , 1O1I , 1O1J , 1O1K , 1O1L , 1O1M , 1O1N , 1O1O , 1O1P , 1QI8 , 1QSH , 1QSI , 1QXD , 1QXE , 1R1X , 1R1Y , 1RPS , 1RQ3 , 1RQ4 , 1RQA , 1RVW , 1SDK , 1SDL , 1SHR , 1SI4 , 1THB , 1UIW , 1VWT , 1XXT , 1XY0 , 1XYE , 1XZ2 , 1XZ4 , 1XZ5 , 1XZ7 , 1XZU , 1XZV , 1Y01 , 1Y09 , 1Y0A , 1Y0C , 1Y0D , 1Y0T , 1Y0W , 1Y22 , 1Y2Z , 1Y31 , 1Y35 , 1Y45 , 1Y46 , 1Y4B , 1Y4F , 1Y4G , 1Y4P , 1Y4Q , 1Y4R , 1Y4V , 1Y5F , 1Y5J , 1Y5K , 1Y7C , 1Y7D , 1Y7G , 1Y7Z , 1Y83 , 1Y85 , 1Y8W , 1YDZ , 1YE0 , 1YE1 , 1YE2 , 1YEN , 1YEO , 1YEQ , 1YEU , 1YEV , 1YFF , 1YG5 , 1YGD , 1YGF , 1YH9 , 1YHE , 1YHR , 1YIE , 1YIH , 1YVQ , 1YVT , 1YZI , 1Z8U , 2D5Z , 2D60 , 2DN1 , 2DN2 , 2DN3 , 2DXM , 2H35 , 2HBC , 2HBD , 2HBE , 2HBF , 2HBS , 2HCO , 2HHD , 2HHE , 2M6Z , 2W6V , 2W72 , 2YRS , 3B75 , 3D17 , 3D7O , 3DUT , 3HXN , 3IA3 , 3IC0 , 3IC2 , 3KMF , 3NL7 , 3NMM , 3ODQ , 3ONZ , 3OO4 , 3OO5 , 3OVU , 3P5Q , 3QJB , 3QJC , 3QJD , 3QJE , 3R5I , 3S48 , 3S65 , 3S66 , 3SZK , 3WCP , 3WHM , 4FC3 , 4HHB , 4IJ2 , 4L7Y , 4M4A , 4M4B , 4MQC , 4MQG , 4MQH , 4MQI , 4MQJ , 4MQK , 4N7N , 4N7O , 4N7P , 4N8T , 4NI0 , 4NI1 , 4ROL , 4ROM , 4WJG , 4X0L , 4XS0 , 6HBW , 5E29 , 5E6E , 5EE4 , 5HU6 , 5JDO , 5KDQ , 5E83 ,%%s 1Y01 , 1Z8U , 1BZ1 3039 15122 ENSG00000206172 ENSMUSG00000069919 P69905 Q91VB8 NM_000558 NM_008218 NP_000508 NP_000508.1 NP_000549.1 NP_001077424 Hemoglobin subunit alpha , Hemoglobin, alpha 1,
6-456: Is a hemoglobin protein that in humans is encoded by the HBA1 gene . The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 ( HBA2 ) and alpha-1 (HBA1; this gene) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and
9-452: The introns , but they differ significantly over the 3' untranslated regions . Two alpha chains plus two beta chains constitute HbA , which in normal adult life accounts for about 97% of the total hemoglobin ; alpha chains combine with delta chains to constitute HbA-2 , which with fetal hemoglobin (HbF), composed of alpha and gamma chains, make up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of
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