75-499: (Redirected from C-5 ) C5 , C05 , C V or C-5 may refer to: Military use [ edit ] Lockheed C-5 Galaxy , a military transport aircraft C-5 North Star , a 1940s Canadian military aircraft HMS C5 , a 1906 Royal Navy C-class submarine USS C-5 (SS-16) , a 1908 United States Navy C-class submarine USS San Francisco (C-5) , an 1889 United States Navy protected cruiser Albatros C.V ,
150-563: A T-tail , while the designs by Boeing and Douglas had conventional tails. The Air Force considered Boeing's design to be better than that of Lockheed, but Lockheed's proposal was the lowest total-cost bid. Lockheed was selected as the winner in September 1965, then awarded a contract in December 1965. General Electric's TF39 engine was selected in August 1965 to power the new transport plane. At
225-466: A 2018 album by Lil Wayne Central 5 , an informal political cooperation between Austria, the Czech Republic, Hungary, Slovakia, and Slovenia C 5 , the cycle graph with 5 vertices See also [ edit ] CV (disambiguation) 5C (disambiguation) [REDACTED] Topics referred to by the same term This disambiguation page lists articles associated with the same title formed as
300-636: A 30% shorter takeoff, a 38% higher climb rate to initial altitude, an increased cargo load and a longer range. Upgraded C-5s are designated C-5M Super Galaxy . Lockheed also planned a civilian version of the C-5 Galaxy, the L-500 , the company designation also used for the C-5 itself. Both passenger and cargo versions of the L-500 were designed. The all-passenger version would have been able to carry up to 1,000 travelers, while
375-416: A World War I German military reconnaissance aircraft AEG C.V , a World War I prototype German two-seat biplane reconnaissance aircraft DFW C.V , a World War I German military reconnaissance aircraft Fokker C.V , a 1924 Dutch light reconnaissance and bomber biplane aircraft Halberstadt C.V , a World War I German single-engined reconnaissance biplane Fokker C-5 , an American military version of
450-516: A car manufactured by Citroën Omoda C5 , a car manufactured by Chery Sauber C5, a sportscar by Sauber Audi A6 (C5), the second generation of the Audi A6 built from 1997 to 2004 Sinclair C5 , an electric vehicle designed by Clive Sinclair Circumferential Road 5 or C-5, an arterial road of Manila, Philippines Air travel and aircraft vehicles [ edit ] Kinner C-5 , an American five cylinder radial engine for small aircraft of
525-548: A cargo load trainer at Lackland AFB, Texas, and one was sent to the Warner Robins Air Logistics Center (WR-ALC) for tear down and inspection to evaluate structural integrity and estimate the remaining life for the fleet. The U.S. Air Force began to receive refitted C-5M aircraft in December 2008. Full production of C-5Ms began in the summer of 2009. In 2009, the Congressional ban on the retirement of C-5s
600-720: A civilian jet liner, the Lockheed L-1011 . The U.S. government gave loans to Lockheed to keep the company operational. In the early 1970s, NASA considered the C-5 for the Shuttle Carrier Aircraft role, to transport the Space Shuttle to Kennedy Space Center . However, they rejected it in favor of the Boeing 747 , in part due to the 747's low-wing design. In contrast, the Soviet Union chose to transport its shuttles using
675-400: A ground stop for even the most routine long-distance flights. We spent a lot of money to make it capable of operating from unfinished airstrips near the front lines, when we never needed that capability or had any intention to use it. Robert F. Dorr, aviation historian Aircraft weight was a serious issue during design and development. At the time of the first flight, the weight was below
750-607: A higher expected operating cost. The plan was canceled in favor of the purchase of more C-17s. The specifications of the C-5D were later used in the C-5M upgrade program. Following a study showing that 80% of the C-5 airframe's service life was remaining, Air Mobility Command (AMC) began an aggressive program to modernize all remaining C-5Bs and C-5Cs and many of the C-5As. The C-5 Avionics Modernization Program (AMP) began in 1998 and includes upgrading
825-693: A larger cargo bay than the C-141, whose interior was too small to carry a variety of their outsized equipment . This need led to the CX-4 requirement of July 1962, for which Lockheed, Boeing, Convair, and Douglas proposed six-engined designs. When the US Army judged the CX-4 specification inadequate for its requirements, by late 1963 the CX-4 specification gave way to the CX-HLC requirement specified an airlifter with four engines, an equipped gross weight of 550,000 pounds (249,000 kg),
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#1732845376647900-506: A letter–number combination. If an internal link led you here, you may wish to change the link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=C5&oldid=1222862323 " Category : Letter–number combination disambiguation pages Hidden categories: Short description is different from Wikidata All article disambiguation pages All disambiguation pages Lockheed C-5 Galaxy The Lockheed C-5 Galaxy
975-414: A maximum payload of 180,000 lb (81,600 kg), and a speed of Mach 0.75 (500 mph or 805 km/h). The cargo compartment was 17.2 ft (5.24 m) wide by 13.5 feet (4.11 m) high and 100 ft (30.5 m) long with front and rear access doors. USAF studies showed that high-bypass turbofan engines were needed for thrust and fuel efficiency requirements. We started to build
1050-508: A mix of palletized cargo and vehicles. The nose and aft cargo-bay doors open the full width and height of the cargo bay to maximize efficient loading of oversized equipment. Full-width ramps enable loading double rows of vehicles from either end of the cargo hold. The C-5 Galaxy is capable of moving nearly every type of military combat equipment, including such bulky items as the Army armored vehicle launched bridge , at 74 short tons (67 t), from
1125-601: A new version of the C-5, the C-5B, in July 1982, to expand airlift capacity. The first C-5B was delivered to Altus Air Force Base in January 1986. In April 1989, the last of 50 C-5B aircraft was added to the 77 C-5As in the Air Force's airlift force structure. The C-5B includes all C-5A improvements and numerous additional system modifications to improve reliability and maintainability. In 1998,
1200-662: A polarised, three pole, mains voltage IEC appliance connector ChorusOS , a computer operating system C5, CommutAir IATA code C5 or Tenor C , a musical note c5, a square of the chessboard using algebraic chess notation Microsoft Dynamics C5 , enterprise resource planning software Channel 5 (disambiguation) Nokia C5 (disambiguation) , a series of smartphones Caldwell 5 ( IC 342 ), an intermediate spiral galaxy in Camelopardalis Concrete5 , an open source content management system A line of earphones from Bowers & Wilkins Tha Carter V ,
1275-551: A series of forklifts by the Crown Equipment Corporation Saturn C-5 , an American man-rated expendable rocket Biology [ edit ] Cervical vertebra 5 , one of the cervical vertebrae of the vertebral column Cervical spinal nerve 5 Complement component 5 , a protein of the complement system C5-convertase , an enzyme which splits C5 into C5b Complement component 5a , an inflammatory peptide ATC code C05 Vasoprotectives ,
1350-743: A similar climate as to their acquisition of F-14 Tomcat fighters. However, no C-5s were ordered by Iran, and the prospect was firmly halted by the Iranian Revolution in 1979 when the Imperial State of Iran was replaced by the Islamic State of Iran . As part of President Ronald Reagan 's military policy, funding was made available for expansion of the USAF's airlift capability. With the C-17 program still some years from completion, Congress approved funding for
1425-592: A smaller turning radius, and rotates 90° after takeoff before being retracted. "Kneeling" landing gear permits lowering the aircraft when parked, thereby presenting the cargo deck at truck-bed height to facilitate loading and unloading operations. The C-5 features a malfunction detection analysis and recording system to identify errors throughout the aircraft. The cargo compartment is 121 ft (37 m) long, 13.5 ft (4.1 m) high, and 19 ft (5.8 m) wide, or just over 31,000 cu ft (880 m ). It can accommodate up to 36 463L master pallets or
1500-514: A subgroup of the Anatomical Therapeutic Chemical Classification System C05, Malignant neoplasm of palate ICD-10 code Other uses [ edit ] C5 (classification) , a Paralympic cycling classification C5 Envelope size C5 , a decision tree learning algorithm C5 Generic Collection Library for C Sharp and CLI , a software library by Niels Kokholm and Peter Sestoft C5 line socket,
1575-489: A takeoff weight of 649,680 lb (294,690 kg) including payload, fuel, and other equipment. On 18 July 2017, C-5s based at Dover were ordered to stand down so maintenance crews could determine the cause for some nose landing gear failing. The last TF39-powered C-5 flew in late 2017. The C-5A is the original version of the C-5. From 1969 to 1973, 81 C-5As were delivered to the Military Airlift Command of
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#17328453766471650-493: Is a large military transport aircraft designed and built by Lockheed , and now maintained and upgraded by its successor, Lockheed Martin . It provides the United States Air Force (USAF) with a heavy intercontinental-range strategic airlift capability, one that can carry outsized and oversized loads, including all air-certifiable cargo. The Galaxy has many similarities to the smaller Lockheed C-141 Starlifter and
1725-462: Is a large, high-wing cargo aircraft with a distinctive high T-tail fin (vertical) stabilizer, with four TF39 turbofan engines mounted on pylons beneath wings that are swept 25°. (The C-5M uses newer GE CF6 engines.) Similar in layout to its smaller predecessor, the C-141 Starlifter, the C-5 has 12 internal wing tanks and is equipped for aerial refueling . Above the plane-length cargo deck
1800-525: Is a much less potent anaphylatoxin. Both C5a and C5a des-Arg can trigger mast cell degranulation, releasing proinflammatory molecules histamine and TNF-α . C5a is also an effective chemoattractant , initiating accumulation of complement and phagocytic cells at sites of infection or recruitment of antigen-presenting cells to lymph nodes. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. White blood cells are activated by upregulation of integrin avidity ,
1875-399: Is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system such as sepsis, rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythemotosis, psoriasis. The inhibitor of C5a that can block its effects would be helpful in medical applications. Another candidate is PMX53 or PMX205 that
1950-599: Is a protein fragment released from cleavage of complement component C5 by protease C5-convertase into C5a and C5b fragments. C5b is important in late events of the complement cascade, an orderly series of reactions which coordinates several basic defense mechanisms, including formation of the membrane attack complex (MAC), one of the most basic weapons of the innate immune system, formed as an automatic response to intrusions from foreign particles and microbial invaders. It essentially pokes microscopic pinholes in these foreign objects, causing loss of water and sometimes death. C5a,
2025-458: Is a short 1.5 turn helix on N-terminus but all agonist activity take place in the C-terminus . C5a is rapidly metabolised by a serum enzyme carboxypeptidase B to a 72 amino acid form C5a des-Arg without C terminal arginine. C5a is an anaphylatoxin , causing increased expression of adhesion molecules on endothelium, contraction of smooth muscle, and increased vascular permeability. C5a des-Arg
2100-579: Is an upper deck for flight operations and for seating 80 passengers in rear facing seats (unlike most commercial airplanes) and the embarked loadmaster crew in forward facing seats. Bay doors at both nose and tail open to enable "drive-through" loading and unloading of cargo. The cargo hold of the C-5 is one foot (30 cm) longer than the entire length of the first powered flight by the Wright brothers at Kitty Hawk, North Carolina . For its voracious consumption of fuel and its maintenance and reliability issues
2175-570: Is enhanced by lipopolysaccharides exposure. C5a, acting via C5aR1, is shown to differentially modulate lipopolysaccharides-induced inflammatory responses in primary human monocytes versus macrophages, yet this is not due to C5aR1 upregulation. C5L2 is another C5a receptor that is thought to regulate the C5a-C5aR1 effects. There is apparently contradictory evidence showing decoy receptor activity conferring anti-inflammatory properties and also signalling activity conferring pro-inflammatory properties. C5a
2250-400: Is essential in the innate immunity but it is also linked with the adaptive immunity. The increased production of C5a is connected with a number of inflammatory diseases. Human polypeptide C5a contains 74 amino acids and has 11kDa. NMR spectroscopy proved that the molecule is composed of four helices and connected by peptide loops with three disulphide bonds between helix IV and II, III. There
2325-512: Is highly specific for CD88 and effectively reduces inflammatory response. C5a has been identified as a key mediator of neutrophil dysfunction in sepsis , with antibody blockade of C5a improving outcomes in experimental models. This has also been shown in humans, with C5a-mediated neutrophil dysfunction predicting subsequent nosocomial infection and death from sepsis. Recent data demonstrates that C5a not only impairs phagocytosis by neutrophils but also impairs phagosomal maturation, inducing
C5 - Misplaced Pages Continue
2400-604: The American Ethical Union honored Durham with the Elliott-Black Award. The Deputy Assistant Secretary of the Air Force for Management Systems, Ernest Fitzgerald, was another person whose fostering of public accountability was unwelcome. Upon completion of testing in December 1969, the first C-5A was transferred to the Transitional Training Unit at Altus Air Force Base , Oklahoma. Lockheed delivered
2475-627: The Gulf War . The Galaxy has also distributed humanitarian aid, provided disaster relief, and supported the US space program. In 1961, several aircraft companies began studying heavy jet transport designs that would replace the Douglas C-133 Cargomaster and complement Lockheed C-141 Starlifters . In addition to higher overall performance, the United States Army wanted a transport aircraft with
2550-526: The National Aeronautic Association for formal recognition. The C-5M had carried a payload of 176,610 lb (80,110 kg) to over 41,100 ft (12,500 m) in 23 minutes, 59 seconds. Additionally, 33 time to climb records at various payload classes were set, and the world record for greatest payload to 6,562 ft (2,000 m) was broken. The aircraft was in the category of 551,200 to 661,400 lb (250,000 to 300,000 kg) with
2625-791: The lipoxygenase pathway and arachidonic acid metabolism. C5a also modulates the balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing the autoimmune response. C5a interact with receptor protein C5a Receptor 1 ( C5aR1 ) on the surface of target cells such as macrophages, neutrophils and endothelial cells. C5aR1 is a member of the G-protein-coupled receptor superfamily of proteins, predicted to have seven transmembrane helical domains of largely hydrophobic amino acid residues, forming three intra- and three extra-cellular loops, with an extracellular N-terminus and an intracellular C-terminus. C5a binding to
2700-501: The "Heavy Logistics System" (CX-HLS) (previously CX-HLC). In May 1964, proposals for aircraft were received from Boeing , Douglas , General Dynamics , Lockheed , and Martin Marietta . General Electric , Curtiss-Wright , and Pratt & Whitney submitted proposals for the engines. After a downselect, Boeing, Douglas, and Lockheed were given one-year study contracts for the airframe, along with General Electric and Pratt & Whitney for
2775-483: The 1930s Spartan C5 , a passenger and utility aircraft produced in the United States in the early 1930s Rail [ edit ] Bavarian C V , an 1899 German express train locomotive model WLWR Class C5, a Waterford, Limerick and Western Railway Irish steam locomotive Finnish Steam Locomotive Class C5 LNER Class C5 , a class of British steam locomotives Other [ edit ] Crown C-5,
2850-502: The 1990s Non-Developmental Airlift Aircraft (NDAA) program as an alternative to further purchases of the McDonnell Douglas C-17 Globemaster III as well as a replacement for older C-5As. The C-5D was to have General Electric F138-GE-100 (CF6-80C2) engines, improved avionics and significantly improved reliability and maintainability, although it could not use austere runways or conduct airdrop operations and had
2925-424: The 76 completed C-5As to restore full payload capability and service life began in 1976. After design and testing of the new wing design, the C-5As received their new wings from 1980 to 1987. In 1974, Imperial Iran , having good relations with the United States, offered $ 160 million (equivalent to $ 989 million today) to restart C-5 production to enable Iran to purchase aircraft for their own air force, in
3000-557: The Air Force Reserve Command's 433d Airlift Wing at Lackland AFB / Kelly Field, Texas, and 439th Airlift Wing at Westover ARB, Massachusetts. The last operational C-5A was retired on 7 September 2017. The C-5B is an improved version of the C-5A. It incorporated all modifications and improvements made to the C-5A with improved wings, simplified landing gear, upgraded TF-39-GE-1C turbofan engines and updated avionics. Fifty examples of
3075-585: The Avionics Modernization Program (AMP) began upgrading the C-5's avionics to include a glass cockpit , navigation equipment, and a new autopilot system. Another part of the C-5 modernization effort is the Reliability Enhancement and Re-engining Program (RERP). The program replaced the engines with newer, more powerful ones. A total of 52 C-5s were contracted to be modernized, consisting of 49 B-, two C- and one A-model aircraft through
C5 - Misplaced Pages Continue
3150-665: The British-led peacekeeper initiative in Zimbabwe in 1979. On 24 October 1974, the Space and Missile Systems Organization successfully conducted an air-launched ballistic missile test, where a C-5A Galaxy aircraft air dropped an 86,000-pound (39,000 kg) Minuteman ICBM from 20,000 feet (6,100 m) over the Pacific Ocean. The missile descended to 8,000 feet (2,400 m) before its rocket engine fired. The 10-second engine burn carried
3225-549: The C-5 and wanted to build the biggest thing we could … Quite frankly, the C-5 program was a great contribution to commercial aviation. We'll never get credit for it, but we incentivized that industry by developing [the TF39] engine. General Duane H. Cassidy , former MAC Commander in Chief The criteria were finalized and an official request for proposal was issued in April 1964 for
3300-592: The C-5, and later the L-1011 , which led to the governmental rescue of the company. Lockheed proposed a twin body C-5 as a Shuttle Carrier Aircraft to counter the Conroy Virtus , but the design was turned down in favor of the Boeing 747 . United States Air Force – 52 C-5Ms in service as of August 2018 Air Mobility Command Air Force Reserve Command Military Airlift Command / Air Mobility Command Air Force Reserve Complement component 5a C5a
3375-541: The Fokker F.VII aircraft SM UC-5 , a 1915 German Type UC I U-boat C-5 (blimp) , a United States Navy airship that attempted a trans-Atlantic flight in 1919 Transport, vehicles, roads, public transport routes [ edit ] Road [ edit ] C5 automatic , a successor to Ford C4 transmission Chevrolet Corvette C5 , the fifth generation of the Chevrolet Corvette sports car Citroën C5 ,
3450-492: The Galaxy's aircrews have nicknamed it "FRED", for Fucking Ridiculous Economic/Environmental Disaster. Takeoff and landing distance requirements for the plane at maximum-load gross weight are 8,300 ft (2,500 m) and 4,900 ft (1,500 m), respectively. Its high-flotation main landing gear provides 28 wheels to distribute gross weight on paved or earth surfaces. The rear main landing gear can be made to caster to make
3525-824: The RERP. The program featured over 70 changes and upgrades, including the newer General Electric engines. Three C-5s underwent RERP for testing purposes. Low-rate initial production started in August 2009 with Lockheed reaching full production in May 2011; 22 C-5M Super Galaxies have been completed as of August 2014. RERP upgrades were completed on 25 July 2018. The Air Force received the last modified aircraft on 1 August 2018. In 2014 Lockheed investigated drag reduction by plasma-heating of turbulent transonic airflow in critical points, saving overall weight by reducing fuel consumption. The Air Force Research Laboratory looked into shape-memory alloy for speed-dependent vortex generators . The C-5
3600-435: The U.S. Air Force. Due to cracks found in the wings in the mid-1970s, the cargo weight was restricted. To restore the C-5's full capability, the wing structure was redesigned. A program to install new strengthened wings on 77 C-5As was conducted from 1981 to 1987. The redesigned wing made use of a new aluminum alloy that did not exist during the original production. As of August 2016, there were ten A-models in service flown by
3675-493: The USAF decided to convert remaining C-5Bs and C-5Cs into C-5Ms with avionics upgrades and re-engining. The C-5As will receive only the avionics upgrades. The last of 52 C-5Ms was delivered to Air Mobility Command in August 2018. In response to Air Force plans to retire older C-5 aircraft, Congress implemented legislation that set limits on retirement plans for C-5As in 2003. As of November 2013, 45 C-5As have been retired, 11 have been scrapped, parts of one (A/C 66-8306) are now
3750-403: The United States to any location on the globe; and of accommodating up to six Boeing AH-64 Apache helicopters or five Bradley Fighting Vehicles at one time. The first C-5A was delivered to the USAF on 17 December 1969. Wings were built up in the early 1970s at Altus AFB , Oklahoma; Charleston AFB , South Carolina; Dover AFB , Delaware; and Travis AFB , California. The C-5's first mission
3825-466: The all-cargo version was predicted to be able to carry typical C-5 volume for as little as 2 cents per ton-mile (in 1967 dollars). Although some interest was expressed by carriers, no orders were placed for either L-500 version, due to operational costs caused by low fuel efficiency, a significant concern for a profit-making carrier, even before the oil crisis of the 1970s, keen competition from Boeing's 747, and high costs incurred by Lockheed in developing
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#17328453766473900-653: The avionics to comply with Global Air Traffic Management standards, improving communications, fitting new flat-panel displays, improving navigation and safety equipment, and installing a new autopilot system. The first flight of a C-5 with AMP (85-0004) occurred on 21 December 2002. The Reliability Enhancement and Re-engining Program (RERP) began in 2006. It includes fitting new General Electric F138-GE-100 (CF6-80C2) engines, pylons and auxiliary power units, and upgrades to aircraft skin and frame, landing gear, cockpit and pressurization systems. Each CF6 engine produces 22% more thrust (50,000 lbf or 220 kN), providing
3975-569: The dubious distinction of being the first development program with a $ 1‑billion (equivalent to $ 8.3 billion today) overrun. Due to the C-5's troubled development, the Department of Defense abandoned Total Package Procurement . In 1969, Henry Durham raised concerns about the C-5 production process with Lockheed, his employer. Subsequently, Durham was transferred and subjected to abuse until he resigned. The Government Accountability Office substantiated some of his charges against Lockheed. Later,
4050-585: The engines. All three of the designs shared a number of features. The cockpit was placed well above the cargo area to allow for cargo loading through a nose door. The Boeing and Douglas designs used a pod on the top of the fuselage containing the cockpit, while the Lockheed design extended the cockpit profile down the length of the fuselage, giving it an egg-shaped cross section. All of the designs had swept wings , as well as front and rear cargo doors, allowing simultaneous loading and unloading. Lockheed's design featured
4125-474: The first C-5B on 28 December 1985 and the final one in April 1989. The reliability of the C-5 fleet has been a continued issue throughout its lifetime, however the C-5M upgrade program seeks in part to address this issue. Their strategic airlift capacity has been a key logistical component of U.S. military operations in Afghanistan and Iraq . Following an incident during Operation Iraqi Freedom where one C-5
4200-479: The first operational Galaxy to the 437th Airlift Wing , Charleston Air Force Base , South Carolina, in June 1970. Due to higher than expected development costs, in 1970, public calls were made for the government to split the substantial losses that Lockheed was experiencing. Production was nearly brought to a halt in 1971 as Lockheed went through financial difficulties, due in part to the C-5 Galaxy's development, as well as
4275-402: The flaps deflected 40° was higher than predicted (2.60 vs. 2.38), but was lower than predicted with the flaps deflected 25° (2.31 vs. 2.38) and with the flaps retracted (1.45 vs. 1.52). After being one of the worst-run programs, ever, in its early years, it has evolved very slowly and with great difficulty into a nearly adequate strategic airlifter that unfortunately needs in-flight refueling or
4350-413: The guaranteed weight, but by the time of the delivery of the 9th aircraft, had exceeded guarantees. In July 1969, during a fuselage upbending test, the wing failed at 128% of limit load, which is below the requirement that it sustain 150% of limit load. Changes were made to the wing, but during a test in July 1970, it failed at 125% of limit load. A passive load-reduction system, involving uprigged ailerons,
4425-631: The high-winged An-225 , which derived from the An-124 , which is similar in design and function to the C-5. During static and fatigue testing , cracks were noticed in the wings of several aircraft, and as a consequence, the C-5A fleet was restricted to 80% of maximum design loads. To reduce wing loading, load alleviation systems were added to the aircraft. By 1980, payloads were restricted to as low as 50,000 lb (23,000 kg) for general cargo during peacetime operations. A $ 1.5 billion program (equivalent to $ 8 billion today), known as H-Mod, to re-wing
4500-404: The later Boeing C-17 Globemaster III . The C-5 is among the largest military aircraft in the world. The C-5 Galaxy's development was complicated, including significant cost overruns , and Lockheed suffered significant financial difficulties. Shortly after entering service, cracks in the wings of many aircraft were discovered and the C-5 fleet was restricted in capability until corrective work
4575-474: The missile to 20,000 feet (6,100 m) again before it dropped into the ocean. The test proved the feasibility of launching an intercontinental ballistic missile from the air. Operational deployment was discarded due to engineering and security difficulties, though the capability was used as a negotiating point in the Strategic Arms Limitation Talks . Aircraft 69–0014, "Zero-One-Four" used in
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#17328453766474650-401: The new variant were delivered to the U.S. Air Force from 1986 to 1989. The C-5C is a specially modified variant for transporting large cargo. Two C-5As (68-0213 and 68-0216) were modified following major accidents to have a larger internal cargo capacity to accommodate large payloads, such as satellites. The major modifications were the removal of the rear passenger compartment floor, splitting
4725-453: The other cleavage product of C5, acts as a highly inflammatory peptide, encouraging complement activation, formation of the MAC, attraction of innate immune cells, and histamine release involved in allergic responses. The origin of C5 is in the hepatocyte , but its synthesis can also be found in macrophages , where it may cause local increase of C5a. C5a is a chemotactic agent and an anaphylatoxin; it
4800-567: The rear cargo door in the middle, and installing a new movable aft bulkhead further to the rear. The official C-5 technical manual refers to the version as C-5A(SCM) Space Cargo Modified . Modifications also included adding a second inlet for ground power, which can feed any power-dependent equipment that may form part of the cargo. The two C-5Cs are operated by U.S. Air Force crews for DOD spacecraft programs and NASA , and are stationed at Travis AFB, California. Both C-5Cs #68-0213 and #68-0216 have been modified into C-5Ms as of 2017. Proposed during
4875-533: The receptor is a two-stage process: an interaction between basic residues in the helical core of C5a and acidic residues in the extracellular N-terminal domain allows the C-terminus of C5a to bind to residues in the receptor transmembrane domains. The latter interaction leads to receptor activation, and the transduction of the ligand binding signal across the cell plasma membrane to the cytoplasmic G protein G i type GNAI2 . Sensitivity of C5aR1 to C5a stimulation
4950-676: The test was retired to the Air Mobility Command Museum at Dover Air Force Base . The C-5 has been used for several unusual functions. During the development of the secretive stealth fighter, the Lockheed F-117 Nighthawk , Galaxies were often used to carry partly disassembled aircraft, leaving no exterior signs as to their cargo. The C-5 remains the largest aircraft to operate in the Antarctic, capable of operating from Williams Field near McMurdo Station . The C-5 Galaxy
5025-547: The time, GE's engine concept was revolutionary, as all engines before had a bypass ratio less than two-to-one, while the TF39 promised and would achieve a ratio of eight-to-one, which had the benefits of increased engine thrust and lower fuel consumption. Boeing lost the military contract but went on to develop the successful 747 civilian airliner with over 1,500 aircraft built when manufacturing ended in 2022 after 54 years of production. The first C-5A Galaxy ( serial number 66-8303 )
5100-569: The years. During the Yom Kippur War in 1973, multiple C-5s and C-141 Starlifters delivered critical supplies of ammunition, replacement weaponry and other forms of aid to Israel, the US effort was named as Operation Nickel Grass . The C-5 Galaxy's performance in Israel was such that the Pentagon began to consider further purchases. The C-5 was regularly made available to support American allies, such as
5175-452: Was a major supply asset in the international coalition operations in 1990–91 against Iraq in the Gulf War . C-5s have routinely delivered relief aid and humanitarian supplies to areas afflicted with natural disasters or crisis; multiple flights were made over Rwanda in 1994. The C-5 is also used to transport Marine One . The wings on the C-5As were replaced during the 1980s to restore full design capability. The USAF took delivery of
5250-436: Was completed. The C-5M Super Galaxy is an upgraded version with new engines and modernized avionics designed to extend its service life to 2040 and beyond. The USAF has operated the C-5 since 1969. In that time, the airlifter supported US military operations in all major conflicts including Vietnam , Iraq , Yugoslavia , and Afghanistan , as well as allied support, such as Israel during the Yom Kippur War and operations in
5325-441: Was damaged by a projectile, the installation of defensive systems has become a stated priority. The C-5 AMP and RERP modernization programs plan to raise mission-capable rate to a minimum goal of 75%. Over the next 40 years, the U.S. Air Force estimates the C-5M will save over $ 20 billion. The first C-5M conversion was completed on 16 May 2006 and C-5Ms began test flights at Dobbins Air Reserve Base in June 2006. In 2008,
5400-441: Was incorporated, but the maximum allowable payload was reduced from 220,000 to 190,000 lb (100,000 to 86,000 kg). At the time, a 90% probability was predicted that no more than 10% of the fleet of 79 airframes would reach their fatigue life of 19,000 hours without cracking of the wing. Cost overruns and technical problems of the C-5A were the subject of a congressional investigation in 1968 and 1969. The C-5 program has
5475-735: Was on 9 July 1970, in Southeast Asia during the Vietnam War . C-5s were used to transport equipment and troops, including Army tanks and even some small aircraft, throughout the later years of the US action in Vietnam. In the final weeks of the war, prior to the Fall of Saigon , several C-5s were involved in evacuation efforts. During one such mission , a C-5A crashed while transporting a large number of orphans, with over 140 killed. C-5s have also been used to deliver support and reinforce various US allies over
5550-402: Was overturned. The Air Force seeks to retire one C-5A for every 10 new C-17s ordered. In October 2011, the 445th Airlift Wing based at Wright-Patterson Air Force Base replaced all remaining C-5s with C-17s. The C-5M reached initial operating capability (IOC) on 24 February 2014 with 16 aircraft delivered. On 13 September 2009, a C-5M set 41 new records and flight data was submitted to
5625-460: Was rolled out of the manufacturing plant in Marietta, Georgia , on 2 March 1968. On 30 June 1968, flight testing of the C-5A began with the first flight, flown by Leo Sullivan, with the call sign "eight-three-oh-three heavy ". Flight tests revealed that the aircraft exhibited a higher drag divergence Mach number than predicted by wind tunnel data. The maximum lift coefficient measured in flight with
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