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Burroughs Wellcome Fund

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The Burroughs Wellcome Fund (BWF) is an American non-profit medical research organization that provides funding for biomedical research, STEM education, and areas of career development for scientists. Since 1970, it has been headquartered in North Carolina's Research Triangle Park .

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46-736: Founded in 1955 as an extension of the England-based Wellcome Trust , the Burroughs Wellcome Fund's two-part mission is “to help scientists early in their careers develop as independent investigators” and “to advance fields in the basic biomedical sciences that are undervalued or in need of particular encouragement”. The fund grants more than $ 40 million each year to research focusing on infectious disease, biomedical science, and other health-related fields. The Fund also supports STEM education efforts in North Carolina, including

92-620: A café and a bookshop. The galleries show a small sample of works from Sir Henry Wellcome's collection, and host a programme of events and exhibitions. The Wellcome Collection and exhibitions are open to the public free of charge six days a week. The Wellcome Collection and Wellcome Library are members of The London Museums of Health & Medicine . The Wellcome Trust runs an annual photography prize which aims to explore "the human side of three urgent health challenges". Judges in 2021 include Dr Dixon Chabanda, Sir Jeremy Farrar, Dr Katerina Srahulkova and Azu Nwagbogu. Winners in each category receive

138-510: A local currency that is pegged to the U.S. dollar or the New Zealand dollar . The Sovereign Base Areas of Akrotiri and Dhekelia (in Cyprus ) use the euro. Since decimalisation on Decimal Day in 1971, the pound has been divided into 100 pence (denoted on coinage, until 1981, as "new pence"). The symbol for the penny is "p"; hence an amount such as 50p (£0.50) properly pronounced "fifty pence"

184-554: A number of major biomedical research initiatives: Also known as SDDI, this five-year initiative started in October 2005 with the remit "to facilitate the development of drug-like small molecules that address unmet medical needs." SDDI was based in London and managed by Richard Davis. Through early 2010, SDDI had provided more than £80 million across 30 projects split between academic institutions and companies. To early 2010, all but one of

230-399: A penny", "two and a penny", etc. 5 shillings, for example, was written as "5 s ." or, more commonly, "5/–" (five shillings, no pence). Various coin denominations had, and in some cases continue to have, special names, such as florin (2/–), crown (5/–), half crown (2/6 d ), farthing ( 1 ⁄ 4 d ), sovereign (£1) and guinea (21s, 21/–, £1–1–0 or £1.05 in decimal notation). By

276-478: A prize of £10,000. The Wellcome Trust sponsors an annual book prize, the Wellcome Book Prize , which "aims to excite public interest and encourage debate" around medicine and health. In June 2019, Wellcome released the results of the 2018 global survey on public attitudes toward science and health. Topics include trust of scientists, doctors, and nurses; religion and science, and vaccines, among others. It

322-755: A richer research culture. In 2016, the Wellcome Trust partnered with the US National Institutes of Health (NIH) and the Howard Hughes Medical Institute to launch the Open Science Prize to "help develop services, tools and platforms that enable open content to be discovered, assessed and re-used in ways that will advance discovery and spark innovation." In 2016, Wellcome Trust announced that it would be launching Wellcome Open Research, an open access publication system running on

368-417: Is often pronounced "fifty pee" /fɪfti piː/. The old sign d was not reused for the new penny in order to avoid confusion between the two units. A decimal halfpenny ( ⁠ 1 / 2 ⁠ p, worth 1.2 old pennies) was issued until 1984 but was withdrawn due to inflation . Before decimalisation in 1971 , the pound was divided into 20 shillings , and each shilling into 12 pence , making 240 pence to

414-599: Is the central bank for sterling, issuing its own banknotes and regulating issuance of banknotes by private banks in Scotland and Northern Ireland. Sterling banknotes issued by other jurisdictions are not regulated by the Bank of England; their governments guarantee convertibility at par . Historically, sterling was also used to varying degrees by the colonies and territories of the British Empire . There are various theories regarding

460-561: Is the currency of the United Kingdom and nine of its associated territories. The pound ( sign: £ ) is the main unit of sterling, and the word pound is also used to refer to the British currency generally, often qualified in international contexts as the British pound or the pound sterling . Sterling is the world's oldest currency in continuous use since its inception. In 2022, it

506-894: The F1000 Research platform. Article processing charges will be covered directly by Wellcome Trust. Papers from the system are now indexed in PubMed Central . In the summer of 2015, the Wellcome Trust joined the Japanese government, 7 Japanese pharmaceutical and diagnostics companies, The Bill and Melinda Gates Foundation, and the United Nations Development Program as funding partner of the Global Health Innovative Technology Fund (GHIT) , which funds scientific research and development for anti-infectives and diagnostics for diseases that primarily affect

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552-647: The Wellcome Collection and the adjoining glass and steel building at 215 Euston Road is the Gibbs Building, by Hopkins Architects , which opened in 2004 as the administrative headquarters of the Wellcome Trust. In 2019, the Wellcome Trust also opened an office in Berlin. The trust was established to administer the fortune of the American-born British pharmaceutical magnate Sir Henry Wellcome . Its income

598-657: The 1950s, coins of Kings George III , George IV and William IV had disappeared from circulation, but coins (at least the penny) bearing the head of every British monarch from Queen Victoria onwards could be found in circulation. Silver coins were replaced by those in cupro-nickel in 1947, and by the 1960s the silver coins were rarely seen. Silver/cupro-nickel sixpences, shillings (from any period after 1816) and florins (2 shillings) remained legal tender after decimalisation (as 2½p, 5p and 10p respectively) until 1980, 1990 and 1993 respectively, but are now officially demonetised. The pound sterling emerged after

644-469: The Bank of England has exclusively used the single bar variant since 1975. Historically, a simple capital L (in the historic black-letter typeface, L {\displaystyle {\mathfrak {L}}} ) placed before the numerals, or an italic l. after them, was used in newspapers, books and letters. The Royal Mint was still using this style of notation as late as 1939. The glyphs Ł and Ⱡ may occasionally be encountered. Use of

690-530: The Burroughs Wellcome Fund. From 1955 to 1993, it operated as a corporate foundation to support scientific research. In 1993 a $ 400 million gift from the trustees allowed it to become an independent entity with no ties to the Wellcome Foundation or to GlaxoSmithKline , which by 2000 had purchased all shares of Wellcome Foundation. Since its founding, the BWF has funded medical and biological science research across

736-529: The COVID-19 Therapeutics Accelerator, launching in March 2020 with an initial $ 125 million in backing. In September 2019, Wellcome launched an initiative to reimagine research and improve the culture in which research is conducted. Current incentive structures and, as a result, culture and practices, prioritise publication outputs above all else. This is damaging people's wellbeing and undermining

782-453: The League's money was not frequently debased like that of England, English traders stipulated to be paid in pounds of the "Easterlings", which was contracted to "'sterling". The OED dismisses this theory as unlikely, since the stressed first syllable would not have been elided. Encyclopædia Britannica states that the (pre-Norman) Anglo-Saxon kingdoms had silver coins called sterlings and that

828-622: The North Carolina Science, Mathematics, and Technology Education Center. The Burroughs Wellcome Fund was founded in 1955 as an American extension of the Wellcome Trust in England. These foundations trace their origins to the American pharmaceutical magnates Henry Wellcome and Silas Burroughs , who founded Burroughs Wellcome and Co. in England in 1880. This pharmaceutical company was one of

874-498: The Roman libra , solidus , and denarius . Notable style guides recommend that the pound sign be used without any abbreviation or qualification to indicate sterling (e.g., £12,000). The ISO 4217 code "GBP" (e.g., GBP 12,000) may also be seen should disambiguation become necessary. The ISO 4217 currency code for sterling is "GBP", formed from the ISO 3166-1 alpha-2 code for

920-640: The United Kingdom ("GB") and the first letter of "pound". In historical sources and some specialist banking uses, the abbreviation stg (in various styles) has been used to indicate sterling. Many stocks on the London Stock Exchange are quoted in penny sterling, using the unofficial code "GBX". The exchange rate of sterling against the US dollar is referred to as "cable" in the wholesale foreign exchange markets . The origins of this term are attributed to

966-860: The United States and Canada. This has mainly consisted of individual recognition and funding like the Investigator in the Pathogenesis of Infectious Disease Award, the Physician-Scientist Institutional Award, and the Innovation in Regulatory Science Award. The BWF also supports larger research projects conducted by multiple teams, such as a report on "The Domestic and International Impacts of the 2009-H1N1 Influenza A Pandemic." One example of large-scale research supported in part by

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1012-590: The Year program through the North Carolina Department of Public Instruction. In 2013, BWF created the Innovation in Regulatory Science Award to fund regulatory science researchers in the U.S. and Canada. Wellcome Trust The Wellcome Trust is a charitable foundation focused on health research based in London, United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of Burroughs Wellcome , one of

1058-531: The adoption of the Carolingian monetary system in England c.  800 . Here is a summary of changes to its value in terms of silver or gold until 1816. The pound was a unit of account in Anglo-Saxon England . By the ninth century it was equal to 240 silver pence . The accounting system of dividing one pound into twenty shillings , a shilling into twelve pence, and a penny into four farthings

1104-465: The bounds of the pharmaceutical industry. In 1995, the trust divested itself of any interest in pharmaceuticals by selling all remaining stock to Glaxo plc , the company's historic British rival, creating GlaxoWellcome plc. In 2000, the Wellcome name disappeared from the drug business altogether when GlaxoWellcome merged with SmithKline Beecham, to form GlaxoSmithKline plc. The Trust funds or co-funds

1150-474: The common phrase "quids in"). Its origin is unknown: possible derivations include scudo , the name for a number of currency units used in Italy until the 19th century, introduced by Italian immigrants; or from Latin quid via the common phrase quid pro quo , literally, "what for what", or, figuratively, "An equal exchange or substitution". The term "nicker" (also both singular and plural) may also refer to

1196-553: The company recipients were either start-ups or spin-outs . In May 2010, an additional £110 million was added to the SDDI fund with the intent to extend the initiative for an additional five years. The Wellcome Trust announced the need for at least $ 8 billion of new funding for research, development, and supply of treatments related to COVID-19. Wellcome Trust collaborated with the Bill & Melinda Gates Foundation and Mastercard to fund

1242-464: The compound noun pound sterling was derived from a pound (weight) of these sterlings. The English word pound derives from the Latin expression lībra pondō , in which lībra is a noun meaning 'pound' and pondō is a noun, in the ablative case , meaning 'by weight'. The currency sign for the pound unit of sterling is £ , which (depending on typeface) may be drawn with one or two bars :

1288-459: The corporate shares in a new charity entity – the Wellcome Trust . The Trust's purpose was to use profits from the Wellcome Foundation to advance research in medicine and medical history. In 1955, Sir Henry Dale , one of the Trust's original trustees and its chair for 21 years, and William N. Creasy, president and chair of Burroughs Wellcome Co. USA, created a U.S. extension of the Wellcome Trust called

1334-756: The developing world. In June 2007, the Wellcome Building reopened after refurbishment as a public venue, housing the Wellcome Collection , the Wellcome Trust Centre for the History of Medicine at University College London and the Wellcome Library . The aim of the Wellcome Collection is to enhance public understanding of medical science and history. The building contains gallery spaces, conference facilities, space for debates, drama and workshops,

1380-430: The fact that from the mid-19th century, the sterling/dollar exchange rate was transmitted via transatlantic cable. Historically almost every British coin had a widely recognised nickname, such as "tanner" for the sixpence and "bob" for the shilling . Since decimalisation these have mostly fallen out of use except as parts of proverbs. A common slang term for the pound unit is " quid " (singular and plural, except in

1426-406: The four large organizations that eventually merged to become GlaxoSmithKline . After Silas Burroughs passed away in 1895, Henry Wellcome expanded the company into several continents and numerous countries, including the United States. In 1924, Wellcome consolidated all of the company's holdings under a corporate umbrella named The Wellcome Foundation Ltd. When he died in 1936, his will vested all of

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1472-691: The fund was the genetic sequencing of Plasmodium falciparum , the parasite behind most malaria deaths. The BWF partnered with the World Health Organization and the Department of Defense to fund this research at the University of Pennsylvania. In addition to financial support, the Fund facilitated collaboration among the research participants. The Fund is a sponsor of the North Carolina Teacher of

1518-617: The largest providers in the world. According to their annual report, the Wellcome Trust spent GBP £ 1.1 billion on charitable activities across their 2019/2020 financial year. According to the OECD , the Wellcome Trust's financing for 2019 development increased by 22% to US$ 327 million. The Wellcome Trust's operations are run from two buildings on Euston Road in London . The Wellcome Building, at 183 Euston Road, built in 1932 in Portland stone houses

1564-487: The letter ⟨L⟩ for pound derives from medieval Latin documents: "L" was the abbreviation for libra , the Roman pound (weight), which in time became an English unit of weight defined as the tower pound . A "pound sterling" was literally a tower pound (weight) of sterling silver . In the British pre-decimal ( duodecimal ) currency system, the term £sd (or Lsd) for pounds, shillings and pence referred to

1610-576: The origin of the word "sterling". The Oxford English Dictionary states that the "most plausible" etymology is a derivation from the Old English steorra for "star" with the added diminutive suffix -ling , to yield "little star". The reference is to the silver penny used in Norman England in the twelfth century, which bore a small star. Another theory holds that the Hanseatic League

1656-536: The pound. The currency of all the Crown Dependencies ( Guernsey , Jersey , Isle of Man ) and a third of British Overseas Territories ( British Antarctic Territory ; Falkland Islands and South Georgia and the South Sandwich Islands ; Gibraltar ; and Saint Helena, Ascension and Tristan da Cunha ) is either sterling or pegged to sterling at par. The other British Overseas Territories have

1702-594: The pound. The symbol for the shilling was " s ." – not from the first letter of "shilling", but from the Latin solidus . The symbol for the penny was " d .", from the French denier , from the Latin denarius (the solidus and denarius were Roman coins). A mixed sum of shillings and pence, such as 3 shillings and 6 pence, was written as "3/6" or "3 s . 6 d ." and spoken as "three and six" or "three and sixpence" except for "1/1", "2/1" etc., which were spoken as "one and

1748-548: The predecessors of GSK plc ) to fund research to improve human and animal health. The aim of the Trust is to "support science to solve the urgent health challenges facing everyone." It had a financial endowment of £ 29.1 billion in 2020, making it the fourth wealthiest charitable foundation in the world. In 2012, the Wellcome Trust was described by the Financial Times as the United Kingdom's largest provider of non-governmental funding for scientific research, and one of

1794-426: The quality of research itself. The Wellcome Trust plays an important role in encouraging publication of research in open access repositories such as Europe PubMed Central (EuropePMC) . The Wellcome Trust believes that maximising the distribution of these papers – by providing free, online access – is the most effective way of ensuring that the research can be accessed, read and built upon. In turn, this will foster

1840-513: The reign of King Offa of Mercia (757–796), who introduced a "sterling" coin made by physically dividing a Tower pound (5,400 grains, 349.9 grams) of silver into 240 parts. In practice, the weights of the coins were not consistent, 240 of them seldom added up to a full pound; there were no shilling or pound coins and these units were used only as an accounting convenience . Halfpennies and farthings worth 1 ⁄ 2 and 1 ⁄ 4 penny respectively were also minted, but small change

1886-1081: The trust bought the Premier Marinas group. It has been reported that the Wellcome Trust has billions of investments in companies related to the problems the philanthropy wants to solve. In the context of the COVID-19 pandemic , the trust has investments in pharmaceutical companies involved in the development and delivery of treatments for COVID-19, which means it has the potential to gain financially where those treatments are monetised. Pound sterling King Charles III [REDACTED] William, Prince of Wales [REDACTED] Charles III ( King-in-Council ) [REDACTED] Starmer ministry ( L ) Keir Starmer ( L ) Angela Rayner ( L ) ( King-in-Parliament ) [REDACTED] Charles III [REDACTED] [REDACTED] [REDACTED] The Lord Reed The Lord Hodge Andrew Bailey Monetary Policy Committee Sterling ( ISO code : GBP )

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1932-552: Was Wellcome's first Global Monitor and was intended to "provide robust evidence on how public attitudes vary across different demographic groups and countries." In August 2014, the Wellcome Trust bought the Co-operative Group's farm business (renamed Farmcare ) for £249 million. This comprised "15,997 hectares (39,533 acres) of freehold and third party owned land, 15 farms, including three pack houses, over 100 residential properties, and 27 commercial properties." In 2015,

1978-463: Was adopted from the livre carolingienne system introduced by Charlemagne to the Frankish Empire . The penny was abbreviated to "d", from denarius , the Roman equivalent of the penny; the shilling to "s" from solidus (written with a long s , ſ , later evolving into a simple slash , / ); and the pound to "L" (subsequently £ ) from Libra or Livre . The origins of sterling lie in

2024-522: Was derived from what was originally called Burroughs Wellcome , later renamed in the UK as the Wellcome Foundation Ltd. In 1986, the trust sold 25% of Wellcome plc stock to the public. Overseen by incoming Director of Finance Ian Macgregor , this marked the beginning of a period of financial growth that saw the trust's value increase by almost £14 billion in 14 years, as their interests moved beyond

2070-521: Was the fourth-most-traded currency in the foreign exchange market , after the United States dollar , the euro , and the Japanese yen . Together with those three currencies and the renminbi , it forms the basket of currencies that calculate the value of IMF special drawing rights . As of late 2022, sterling is also the fourth most-held reserve currency in global reserves . The Bank of England

2116-563: Was the origin of its definition, manufacture, and name: the German name for the Baltic is Ostsee ( ' East Sea ' ) and from this the Baltic merchants were called Osterlings ( ' Easterlings ' ). In 1260, Henry III granted them a charter of protection and land for their kontor , the Steelyard of London , which by the 1340s was also called Esterlingeshalle ( ' Easterlings Hall ' ). Because

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