6-1056: TGT may stand for: Chemistry [ edit ] Tagetitoxin TRNA-guanine15 transglycosylase , an enzyme Cysteine , an amino acid coded TGT Arts and media [ edit ] TGT (group) , R&B supergroup formed by Tyrese, Ginuwine, and Tank Thailand's Got Talent , Thai reality television series The Grand Tour , British motoring programme Businesses [ edit ] TGT Oil and Gas Services Target Corporation , NYSE stock ticker Tennessee Gas Transmission Company Other uses [ edit ] Tamangic languages (Tamang, Gurung, Thakali and others) Tanga Airport , by IATA code, in Tanga, Tanzania Target (disambiguation) Ticket Granting Ticket , in network security Transitional Government of Tigray , in Ethiopia Trained Graduate Teacher,
12-480: A bicyclic structure (shown at right) based on NMR and mass spectrometry . This structure, however, has been questioned. The absolute configuration remains undetermined, and attempts at confirming the structure by organic synthesis are underway. Recently Porter et al. published a revised structure of TGT based on extensive 2D NMR data. TGT interferes with development of chloroplasts in young plant leaves thereby causing chlorosis . The natural target of
18-478: A teacher who holds a degree for teaching students Topics referred to by the same term [REDACTED] This disambiguation page lists articles associated with the title TGT . If an internal link led you here, you may wish to change the link to point directly to the intended article. Retrieved from " https://en.wikipedia.org/w/index.php?title=TGT&oldid=1143401415 " Category : Disambiguation pages Hidden categories: Short description
24-464: Is different from Wikidata All article disambiguation pages All disambiguation pages Tagetitoxin Tagetitoxin (TGT) is a bacterial phytotoxin produced by Pseudomonas syringae pv. tagetis . When TGT was first isolated, it was only partially characterized. The first proposed chemical structure of TGT involved an eight-membered ring, but this was revised shortly afterward to
30-468: The compound. TGT binds in the RNAP active site and inhibits initiation and elongation phases of transcription as well as pyrophosphorolysis of the nascent RNA. However, the detailed mechanism of inhibition remains a subject of heated debate. It has been suggested that TGT forms a ternary RNAP-NTP-TGT complex and inhibits phosphodiester bond synthesis either by binding an inhibitory magnesium ion or by trapping
36-462: The toxin is chloroplast RNA polymerase. Chloroplast RNA polymerase belongs to ubiquitous family of multisubunit RNA polymerases (RNAP) and is most closely related to bacterial enzymes. In vitro , TGT inhibits bacterial RNAPs from Escherichia coli and Thermus thermophilus , and eukaryotic RNA polymerase III. In contrast, eukaryotic RNA polymerase I and II as well as single-subunit RNA polymerases of bacteriophage T7 and SP6 are relatively insensitive to
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