128-905: Reader's Digest is an American general-interest family magazine, published ten times a year. Formerly based in Chappaqua, New York , it is now headquartered in midtown Manhattan . The magazine was founded in 1922 by DeWitt Wallace and his wife Lila Bell Wallace . For many years, Reader's Digest was the best-selling consumer magazine in the United States; it lost that distinction in 2009 to Better Homes and Gardens . According to Media Mark Research (2006), Reader's Digest reached more readers with household incomes of over $ 100,000 than Fortune , The Wall Street Journal , Business Week , and Inc. combined. Global editions of Reader's Digest reach an additional 40 million people in more than 70 countries, via 49 editions in 21 languages. The periodical has
256-516: A Bank of America office, and various local hardware shops. South Greeley Avenue is also home to Robert E. Bell Middle school, the Chappaqua Library, and the local police station. As of the 2010 census, following a major revision to the delineation of its boundaries by the Census Bureau, the population was 1,436. At the 2000 census, with very different census-defined boundaries, Chappaqua had
384-437: A biopsy of the suspected tissue be histologically examined for cancer cells. Given the location of lung cancer tumors, biopsies can often be obtained by minimally invasive techniques: a fiberoptic bronchoscope that can retrieve tissue (sometimes guided by endobronchial ultrasound ), fine needle aspiration , or other imaging-guided biopsy through the skin. Those who cannot undergo a typical biopsy procedure may instead have
512-490: A biopsy of the suspected tumor be examined by a pathologist under a microscope . In addition to recognizing cancerous cells, a pathologist can classify the tumor according to the type of cells it originates from. Around 15% of cases are small-cell lung cancer (SCLC), and the remaining 85% (the non-small-cell lung cancers or NSCLC) are adenocarcinomas , squamous-cell carcinomas , and large-cell carcinomas . After diagnosis, further imaging and biopsies are done to determine
640-485: A conservative and anti-Communist perspective on political and social issues. The Wallaces initially hoped the journal could provide $ 5,000 of net income. Wallace's assessment of what the potential mass-market audience wanted to read led to rapid growth. By 1929, the magazine had 290,000 subscribers and had a gross income of $ 900,000 a year. The first international edition was published in the United Kingdom in 1938. By
768-420: A direct mail series of hardcover anthologies containing abridged novels and nonfiction. The series was originally called Reader's Digest Condensed Books and renamed in 1997 to Reader's Digest Select Editions . From the mid-1960s to early 1980s, full-length, original works of non-fiction were published under the imprint Reader's Digest Press and distributed by Thomas Y. Crowell Co. Beginning in 1982,
896-551: A liquid biopsy taken (that is, a sample of some body fluid) which may contain circulating tumor DNA that can be detected. Imaging is also used to assess the extent of cancer spread. Positron emission tomography (PET) scanning or combined PET-CT scanning is often used to locate metastases in the body. Since PET scanning is less sensitive in the brain, the National Comprehensive Cancer Network recommends magnetic resonance imaging (MRI) – or CT where MRI
1024-406: A chest radiograph or CT scan. In lung cancer screening studies as many as 30% of those screened have a lung nodule, the majority of which turn out to be benign. Besides lung cancer many other diseases can also give this appearance, including hamartomas , and infectious granulomas caused by tuberculosis , histoplasmosis , or coccidioidomycosis . At diagnosis, lung cancer is classified based on
1152-450: A disbarred attorney drove the body of his severely injured wife to Northern Westchester Hospital, claiming that the couple had been ambushed and shot in the nearby town of Millwood. She died soon after. For over a year, police expressed skepticism about the husband's account and did not rule him out as a suspect. In December 2007 the man was charged with his wife's murder after trying to collect on life insurance policies. Carlos Perez-Olivo
1280-464: A global circulation of 10.5 million, making it the largest paid-circulation magazine in the world. It is also published in Braille , digital, and audio editions, and in a large-type edition called "Reader's Digest Large Print." The magazine is compact: its pages are roughly half the size of most American magazines. With this in mind, in summer 2005, the company adopted the slogan "America in your pocket” for
1408-433: A high-volume surgery clinic improve chances of survival. Those who are unable or unwilling to undergo surgery can instead receive radiation therapy. Stereotactic body radiation therapy is best practice, typically administered several times over 1–2 weeks. Chemotherapy has little effect in those with stage I NSCLC, and may worsen disease outcomes in those with the earliest disease. In those with stage II disease, chemotherapy
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#17328763272311536-439: A mass inside the lung. The X-ray may reveal an obvious mass, the widening of the mediastinum (suggestive of spread to lymph nodes there), atelectasis (lung collapse), consolidation ( pneumonia ), or pleural effusion ; however, some lung tumors are not visible by X-ray. Next, many undergo computed tomography (CT) scanning , which can reveal the sizes and locations of tumors. A definitive diagnosis of lung cancer requires
1664-607: A new cough, or an increase in the frequency or strength of a pre-existing cough. Around one in four cough up blood , ranging from small streaks in the sputum to large amounts. Around half of those diagnosed with lung cancer experience shortness of breath, while 25–50% experience a dull, persistent chest pain that remains in the same location over time. In addition to respiratory symptoms, some experience systemic symptoms including loss of appetite , weight loss , general weakness, fever , and night sweats . Some less common symptoms suggest tumors in particular locations. Tumors in
1792-519: A page of "Amusing Anecdotes" and "Personal Glimpses", two features of funny stories entitled "Humor in Uniform" and "Life in these United States", and a lengthier article at the end, usually condensed from a published book . Other regular features were "My Most Unforgettable Character" (since discontinued), the "Drama in Real Life" survival stories, and more recently "That's Outrageous". These were all listed in
1920-571: A population of 9,468. Note the Chappaqua census-designated-place is different from the Hamlet of Chappaqua, which has a much higher population as part of the Town of New Castle. As of the census of 2010, there were 1,434 people residing in Chappaqua. According to the 2015-2019 American Community Survey 5-Year Estimates, there are 595 housing units and the median household income is $ 250,000+. The racial makeup of
2048-726: A readership of 1.354 million, and in the latest Survey (Quarter 1 of 2019), it is not in the Top 10 list of English-language magazines published in India. According to readership estimates by Roy Morgan , Reader's Digest Australia had an average readership per issue of 362,000 as at September 2023. Nonfiction books with the Reader's Digest brand and yearly collections of the magazine's content are currently published by Trusted Media Brands, sold through their website and distributed to retailers by Simon & Schuster . Since 1950, Reader's Digest has published
2176-497: A second time. The company was purchased for £1 by Mike Luckwell, a venture capitalist and once the biggest shareholder in WPP plc . RDA offers many mail-order products included with " sweepstakes " or contests. US Reader's Digest and the company's other US magazines do not use sweepstakes in their direct-mail promotions. A notable shift to electronic direct marketing has been undertaken by the company to adapt to shifting media landscape. In
2304-488: A series of classic novels was published as World's Best Reading and made available by mail order to magazine subscribers. In Germany, Reader's Digest runs its own book-publishing house called Verlag Das Beste which not only publishes the German edition of the Reader's Digest magazine. Since 1955, it has published Reader's Digest Auswahlbücher (a German edition of Reader's Digest Condensed Books ). Besides publishing
2432-506: A societal level, smoking cessation can be promoted by tobacco control policies that make tobacco products more difficult to obtain or use. Many such policies are mandated or recommended by the WHO Framework Convention on Tobacco Control , ratified by 182 countries, representing over 90% of the world's population. The WHO groups these policies into six intervention categories, each of which has been shown to be effective in reducing
2560-491: A symptom tend to have worse outcomes. Tumor mutations in KRAS are associated with reduced survival. The uncertainty of lung cancer prognosis often causes stress, and makes future planning difficult, for those with lung cancer and their families. Those whose cancer goes into remission often experience fear of their cancer returning or progressing, associated with poor quality of life, negative mood, and functional impairment. This fear
2688-724: A team of Arabic advisers counseled on what would be of interest to Arabic readers. The publication of Al-Mukhtar ceased in April 1993. The Canadian edition first appeared in July 1947 in French and in February 1948 in English; today, the vast majority of its content is Canadian. Nearly all major and minor articles are locally produced or selected from Canadian publications that match the Digest style. Usually, there
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#17328763272312816-547: A total area of 0.45 square miles (1.2 km ), all land. As delineated for the 2000 census, the CDP of Chappaqua covered a much greater area: 9.44 square miles (24.4 km ), of which 9.38 square miles (24.3 km ) was land and 0.06 square miles (0.16 km ), or 0.64%, was water. Parts of the Chappaqua ZIP Code area are located in the towns of Mount Kisco , New Castle , Mount Pleasant , Yorktown , and Bedford , and
2944-427: A tumor, and eventually spreading within and then beyond the lung. Rampant tumor growth and spread causes the symptoms of lung cancer. If unstopped, the spreading tumor will eventually cause the death of affected individuals. Tobacco smoking is by far the major contributor to lung cancer, causing 80% to 90% of cases. Lung cancer risk increases with quantity of cigarettes consumed. Tobacco smoking's carcinogenic effect
3072-520: A variety of other toxic chemicals – typically encountered in certain occupations – is associated with an increased risk of lung cancer. Occupational exposures to carcinogens cause 9–15% of lung cancer. A prominent example is asbestos , which causes lung cancer either directly or indirectly by inflaming the lung. Exposure to all commercially available forms of asbestos increases cancer risk, and cancer risk increases with time of exposure. Asbestos and cigarette smoking increase risk synergistically – that is,
3200-553: A vocabulary competition in schools throughout the US called Reader's Digest National Word Power Challenge . In 2007, the magazine said it would not have the competition for the 2007–08 school year: "...but rather to use the time to evaluate the program in every respect, including scope, mission, and model for implementation." In 2006, the magazine published three more local-language editions in Slovenia , Croatia , and Romania . In October 2007,
3328-502: A year rather than 12, and to increase digital offerings. It also cut its circulation guarantee for advertisers to 5.5 million copies from 8 million. In announcing that decision, in June 2009, the company said that it planned to reduce its number of celebrity profiles and how-to features, and increase the number of inspiring spiritual stories and stories about the military. Beginning in January 2013,
3456-513: A younger age, and in women compared to men. Most lung cancer cases are caused by tobacco smoking . The remainder are caused by exposure to hazardous substances like asbestos and radon gas, or by genetic mutations that arise by chance. Consequently, lung cancer prevention efforts encourage people to avoid hazardous chemicals and quit smoking. Quitting smoking both reduces one's chance of developing lung cancer and improves treatment outcomes in those already diagnosed with lung cancer. Lung cancer
3584-450: A £125 million pension fund deficit. Private equity fund Better Capital paid around £14 million for the brand and invested a further £9 million into the business. Better Capital sold Reader's Digest UK in 2013 for a nominal fee to venture capitalist Mike Luckwell. The brand was sold again in 2018 to its former chief executive Gary Hopkins. The magazine ceased publication after 86 years in April 2024. The first Reader's Digest publication in
3712-1202: Is hypercalcemia (high blood calcium) caused by over-production of parathyroid hormone-related protein or parathyroid hormone . Hypercalcemia can manifest as nausea, vomiting, abdominal pain, constipation, increased thirst , frequent urination , and altered mental status. Those with lung cancer also commonly experience hypokalemia (low potassium) due to inappropriate secretion of adrenocorticotropic hormone , as well as hyponatremia (low sodium) due to overproduction of antidiuretic hormone or atrial natriuretic peptide . About one of three people with lung cancer develop nail clubbing , while up to one in ten experience hypertrophic pulmonary osteoarthropathy (nail clubbing, joint soreness, and skin thickening). A variety of autoimmune disorders can arise as paraneoplastic syndromes in those with lung cancer, including Lambert–Eaton myasthenic syndrome (which causes muscle weakness), sensory neuropathies , muscle inflammation , brain swelling , and autoimmune deterioration of cerebellum , limbic system , or brainstem . Up to one in twelve people with lung cancer have paraneoplastic blood clotting, including migratory venous thrombophlebitis , clots in
3840-505: Is "What [people in various professions] won't tell you," with a different profession featured each time. The first "Word Power" column of the magazine was published in the January 1945 edition, written by Wilfred J. Funk . In December 1952, the magazine published "Cancer by the Carton", a series of articles that linked smoking with lung cancer , and this topic was later repeated in other articles. From 2002 to 2006, Reader's Digest conducted
3968-480: Is a malignant tumor that begins in the lung . Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor. Without treatment, tumors spread throughout the lung, damaging lung function. Eventually lung tumors metastasize , spreading to other parts of
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4096-641: Is also a risk of radiation-induced cancer . The United States Preventive Services Task Force recommends yearly screening using low-dose CT in people between 55 and 80 who have a smoking history of at least 30 pack-years . The European Commission recommends that cancer screening programs across the European Union be extended to include low-dose CT lung scans for current or previous smokers. Similarly, The Canadian Task Force for Preventative Health recommends that people who are current or former smokers (smoking history of more than 30 pack years) and who are between
4224-711: Is approximately 30 miles (50 km) north of New York City . The hamlet is served by the Chappaqua station of the Metro-North Railroad 's Harlem Line . In the New York State Legislature it is within the New York State Assembly 's 93rd district and the New York Senate 's 40th district. In Congress the village is in New York's 17th District . Chappaqua was founded by a group of Quakers in
4352-567: Is associated with the development of the rare lung cancer lymphoepithelioma-like carcinoma in people from Asia, but not in people from Western nations . A role for several other infectious agents – namely human papillomaviruses , BK virus , JC virus , human cytomegalovirus , SV40 , measles virus , and Torque teno virus – in lung cancer development has been studied but remains inconclusive as of 2020. Particular gene combinations may make some people more susceptible to lung cancer. Close family members of those with lung cancer have around twice
4480-413: Is due to various chemicals in tobacco smoke that cause DNA mutations, increasing the chance of cells becoming cancerous. The International Agency for Research on Cancer identifies at least 50 chemicals in tobacco smoke as carcinogenic , and the most potent is tobacco-specific nitrosamines . Exposure to these chemicals causes several kinds of DNA damage: DNA adducts , oxidative stress , and breaks in
4608-528: Is exacerbated by frequent or prolonged surveillance imaging, and other reminders of cancer risks. Lung cancer is caused by genetic damage to the DNA of lung cells. These changes are sometimes random, but are typically induced by breathing in toxic substances such as cigarette smoke. Cancer-causing genetic changes affect the cell's normal functions , including cell proliferation , programmed cell death ( apoptosis ), and DNA repair . Eventually, cells gain enough genetic changes to grow uncontrollably, forming
4736-497: Is impractical are treated with combination chemotherapy and radiotherapy along with the immunotherapy durvalumab . Combined chemotherapy and radiation enhances survival compared to chemotherapy followed by radiation, though the combination therapy comes with harsher side effects. Those with stage IV disease are treated with combinations of pain medication, radiotherapy, immunotherapy, and chemotherapy. Many cases of advanced disease can be treated with targeted therapies depending on
4864-485: Is necessary due to the length of time it can take for lung cancer to develop following an exposure to carcinogens. The smoking of non-tobacco products is not known to be associated with lung cancer development. Marijuana smoking does not seem to independently cause lung cancer – despite the relatively high levels of tar and known carcinogens in marijuana smoke. The relationship between smoking cocaine and developing lung cancer has not been studied as of 2020. Exposure to
4992-506: Is not targetable by current molecular therapies instead can be treated with combination chemotherapy plus immune checkpoint inhibitors, which prevent cancer cells from inactivating immune T cells . The chemotherapeutic agent of choice depends on the NSCLC subtype: cisplatin plus gemcitabine for squamous cell carcinoma, cisplatin plus pemetrexed for non-squamous cell carcinoma. Immune checkpoint inhibitors are most effective against tumors that express
5120-587: Is one American article in each issue. "Life's Like That" is the Canadian name of "Life in These United States". Most of the other rubrics are taken from the American publication. On December 6, 2023, it was announced that Reader's Digest Canada would cease publication in the spring of 2024. The Indian edition was first published in 1954. Its circulation then was 40,000 copies. It was published for many years by
5248-399: Is open during the spring, summer, and the rest of harvest season. The Chappaqua Central School District includes the village. In 2024, Chappaqua Central School District had around 3.5 thousand students from grades K-12, above the national average. Around 1928, Robert E. Bell Middle School, known at the time as Horace Greeley School, was built. The present day Horace Greeley High School
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5376-407: Is present in many lung cancers, but absent from squamous cell carcinomas. Lung cancer staging is an assessment of the degree of spread of the cancer from its original source. It is one of the factors affecting both the prognosis and the treatment of lung cancer. SCLC is typically staged with a relatively simple system: limited stage or extensive stage. Around a third of people are diagnosed at
5504-528: Is provided by Westchester EMS, a non-profit provider. The hamlet is protected by the New Castle Police Department, which also provides first-response services for medical emergencies. The volunteer-based Chappaqua Fire Department, established in 1910, provides firefighting services to the hamlet of Chappaqua. The fire department currently maintains two firehouses in Chappaqua. Lung cancer Lung cancer , also known as lung carcinoma ,
5632-619: Is sorted by year of first publication. Some countries had editions but no longer do; for example, the Danish version of Reader's Digest ( Det Bedste ) ceased publication in 2005 and was replaced by the Swedish version ( Det Bästa ); as a result, the Swedish edition covers stories about both countries (but written solely in Swedish). The United Kingdom edition first published in 1938. Decades later Reader's Digest UK went into administration in 2010 due
5760-402: Is stage IV. Each stage is further subdivided based on the combination of T, N, and M scores. Some countries recommend that people who are at a high risk of developing lung cancer be screened at different intervals using low-dose CT lung scans. Screening programs may result in early detection of lung tumors in people who are not yet experiencing symptoms of lung cancer, ideally, early enough that
5888-405: Is the most diagnosed and deadliest cancer worldwide, with 2.2 million cases in 2020 resulting in 1.8 million deaths. Lung cancer is rare in those younger than 40; the average age at diagnosis is 70 years, and the average age at death 72. Incidence and outcomes vary widely across the world, depending on patterns of tobacco use. Prior to the advent of cigarette smoking in the 20th century, lung cancer
6016-442: Is typically treated with a combination of chemotherapy and radiotherapy. For chemotherapy, the National Comprehensive Cancer Network and American College of Chest Physicians guidelines recommend four to six cycles of a platinum-based chemotherapeutic – cisplatin or carboplatin – combined with either etoposide or irinotecan . This is typically combined with thoracic radiation therapy – 45 Gray (Gy) twice-daily – alongside
6144-420: Is unavailable – to scan the brain for metastases in those with NSCLC and large tumors, or tumors that have spread to the nearby lymph nodes. When imaging suggests the tumor has spread, the suspected metastasis is often biopsied to confirm that it is cancerous. Lung cancer most commonly metastasizes to the brain, bones, liver, and adrenal glands . Lung cancer can often appear as a solitary pulmonary nodule on
6272-564: Is usually initiated six to twelve weeks after surgery, with up to four cycles of cisplatin – or carboplatin in those with kidney problems, neuropathy , or hearing impairment – combined with vinorelbine , pemetrexed , gemcitabine, or docetaxel . Treatment for those with stage III NSCLC depends on the nature of their disease. Those with more limited spread may undergo surgery to have the tumor and affected lymph nodes removed, followed by chemotherapy and potentially radiotherapy. Those with particularly large tumors (T4) and those for whom surgery
6400-454: The 1904 Chappaqua tornado . In 1846 when the New York and Harlem Railroad extended through Chappaqua, business became centered on the new train station . These businesses included a hotel, livery stables, a public library, and various stores and small factories. The railroad enabled commuters to travel to New York City and back each day. According to the 2020 U.S. census , Chappaqua has
6528-618: The Arab World was printed in Egypt in September 1943. The license was eventually withdrawn. The second effort and the first Reader's Digest franchise agreement was negotiated through the efforts of Frederick Pittera, in 1976, an American entrepreneur, who sold the idea to Lebanon 's former foreign minister, Lucien Dahdah , then son-in-law of Suleiman Frangieh , President of Lebanon . Dahdah partnered with Ghassan Tueni (former Lebanon ambassador to
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#17328763272316656-573: The Committee of Advertising Practice code. Reader's Digest was told not to use this mailing again. International editions have made Reader's Digest the best-selling monthly journal in the world. Its worldwide circulation including all editions has reached 17 million copies and 70 million readers. Reader's Digest is currently published in 49 editions and 21 languages and is available in over 70 countries, including Slovenia, Croatia, and Romania in 2008. Its international editions account for about 50% of
6784-624: The Digest expanded into Serbia . The magazine's licensee in Italy stopped publishing in December 2007. The magazine launched in the People's Republic of China in January 2008. It ceased publishing in China in 2012, due to a lack of sales caused by a relatively high price, a poorly defined audience and low-quality translated content. For 2010, the US edition of the magazine reduced its publishing schedule to 10 times
6912-557: The Tata Group of companies. Today, the magazine is published in India by Living Media India Ltd, and sold over 600,000. It prints Indian and international articles. According to the Indian Readership Survey Round II of 2009, the readership for Reader's Digest was 3.94 million , second only to India Today at 5.62 million. That has since declined. In the 2017 Survey, the India edition had fallen to ninth position with
7040-584: The cell division cycle , cellular stress responses , and chromatin remodeling . Some rare genetic disorders that increase the risk of various cancers also increase the risk of lung cancer, namely retinoblastoma and Li–Fraumeni syndrome . As with all cancers, lung cancer is triggered by mutations that allow tumor cells to endlessly multiply, stimulate blood vessel growth , avoid apoptosis (programmed cell death), generate pro-growth signalling molecules, ignore anti-growth signalling molecules, and eventually spread into surrounding tissue or metastasize throughout
7168-508: The spinal cord . Metastasis into the bone marrow can deplete blood cells and cause leukoerythroblastosis (immature cells in the blood). Liver metastases can cause liver enlargement , pain in the right upper quadrant of the abdomen , fever, and weight loss. Lung tumors often cause the release of body-altering hormones , which cause unusual symptoms, called paraneoplastic syndromes . Inappropriate hormone release can cause dramatic shifts in concentrations of blood minerals . Most common
7296-450: The thorax can cause breathing problems by obstructing the trachea or disrupting the nerve to the diaphragm ; difficulty swallowing by compressing the esophagus ; hoarseness by disrupting the nerves of the larynx ; and Horner's syndrome by disrupting the sympathetic nervous system . Horner's syndrome is also common in tumors at the top of the lung , known as Pancoast tumors , which also cause shoulder pain that radiates down
7424-500: The 1730s and was the home of Horace Greeley , New-York Tribune editor and U.S. congressman. He now names Chappaqua's high school. A few notable people have called Chappaqua home. Leo Esaki , a Japanese physicist, was living in town when he won the Nobel Prize for Physics in 1973. Since the late 1990s, the 42nd president of the United States , Bill Clinton , and the 67th secretary of State, Hillary Clinton , have lived there. In
7552-496: The 40th anniversary of Reader's Digest , it had 40 international editions, in 13 languages and Braille, and at one point, it was the largest-circulating journal in China , Mexico , Spain , Sweden , Peru , and other countries, with a total international circulation of 23 million. The magazine's format for several decades consisted of 30 articles per issue (one per day), along with an "It Pays to Increase your Word Power" vocabulary quiz,
7680-457: The CDP was 76.1% White alone, 0% Black or African American alone, 0% Native American alone, 22.6% Asian alone, 0% Native Hawaiian and other Pacific Islander alone, 0% some other race alone, and 1.3% from two or more races. According to the 2010 census], the median age was 39 years, with 3.8% of the population under 5, 81.6% 18 and older, and 10% 65 and older. Males had a median income of $ 207,083 versus $ 128,750 for females. 0% of families were below
7808-469: The DNA strands. Being around tobacco smoke – called passive smoking – can also cause lung cancer. Living with a tobacco smoker increases one's risk of developing lung cancer by 24%. An estimated 17% of lung cancer cases in those who do not smoke are caused by high levels of environmental tobacco smoke. Vaping may be a risk factor for lung cancer, but less than that of cigarettes, and further research as of 2021
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#17328763272317936-606: The U.S. edition. In January 2008, however, it changed the slogan to "Life well shared." In 1920, Dewitt Wallace married Lila Bell Wallace in Pleasantville, New York . Shortly thereafter, the two would launch Reader's Digest in the basement below a Greenwich Village speakeasy . The idea for Reader's Digest was to gather a sampling of favorite articles on many subjects from various monthly magazines, sometimes condensing and rewriting them, and to combine them into one magazine. Since its inception Reader's Digest has maintained
8064-554: The U.S. version of the magazine, but over time they became unique editions, providing material more germane to local readers. Local editions that still publish the bulk of the American Reader's Digest are usually titled with a qualifier, such as the Portuguese edition, Seleções do Reader's Digest ( Selections from Reader's Digest ), or the Swedish edition, Reader's Digest Det Bästa ( The Best of Reader's Digest ). The list
8192-416: The US edition was increased to 12 times a year. In 1990, the magazine's parent company, The Reader's Digest Association, Inc. (RDA), became a publicly traded corporation. From 2005 through 2010, RDA reported a net loss each year. In March 2007, Ripplewood Holdings LLC led a consortium of private-equity investors who bought the company through a leveraged buyout for US$ 2.8 billion, financed primarily by
8320-561: The US$ 2.2 billion debt undertaken by the leveraged buyout transaction. The company emerged from bankruptcy with the lenders exchanging debt for equity, and Ripplewood's entire equity investment was extinguished. In April 2010, the UK arm was sold to its management . It has a licensing deal with the US company to continue publishing the UK edition. The closure of the UK edition was announced in April 2024. On February 17, 2013, RDA Holding filed for bankruptcy
8448-579: The US, China, South Korea, Taiwan, Israel, Latvia, Iceland, Sweden, Austria, and Switzerland. SCLC is particularly aggressive. 10–15% of people survive five years after a SCLC diagnosis. As with other types of lung cancer, the extent of disease at diagnosis also influences prognosis. The average person diagnosed with limited-stage SCLC survives 12–20 months from diagnosis; with extensive-stage SCLC around 12 months. While SCLC often responds initially to treatment, most people eventually relapse with chemotherapy-resistant cancer, surviving an average 3–4 months from
8576-611: The United Nations , and publisher of Al Nahar newspaper, Beirut ) in publishing Reader's Digest in the Arabic language. It was printed in Cairo for distribution throughout the Arab world under title Al-Mukhtar . In format, Al-Mukhtar was the same as the U.S. edition with 75% of the editorial content. Philip Hitti , Chairman of Princeton University 's Department of Oriental Languages and
8704-426: The affected individual loses the ability to swallow. Coughing is also common, and can be managed with opioids or cough suppressants . Some experience terminal delirium – confused behavior, unexplained movements, or a reversal of the sleep-wake cycle – which can be managed by antipsychotic drugs, low-dose sedatives, and investigating other causes of discomfort such as low blood sugar , constipation , and sepsis . In
8832-593: The ages of 55–74 years be screened for lung cancer. Treatment for lung cancer depends on the cancer's specific cell type, how far it has spread , and the person's health. Common treatments for early stage cancer includes surgical removal of the tumor, chemotherapy , and radiation therapy . For later-stage cancer, chemotherapy and radiation therapy are combined with newer targeted molecular therapies and immune checkpoint inhibitors . All lung cancer treatment regimens are combined with lifestyle changes and palliative care to improve quality of life. Limited-stage SCLC
8960-515: The average person's lifespan by around 2 months. For stage I and stage II NSCLC the first line of treatment is often surgical removal of the affected lobe of the lung. For those not well enough to tolerate full lobe removal, a smaller chunk of lung tissue can be removed by wedge resection or segmentectomy surgery. Those with centrally located tumors and otherwise-healthy respiratory systems may have more extreme surgery to remove an entire lung ( pneumonectomy ). Experienced thoracic surgeons , and
9088-399: The blocking tissue by bronchoscopy, sometimes aided by thermal or laser ablation . Other causes of lung cancer-associated shortness of breath can be treated directly, such as antibiotics for a lung infection, diuretics for pulmonary edema , benzodiazepines for anxiety, and steroids for airway obstruction. Up to 92% of those with lung cancer report pain, either from tissue damage at
9216-473: The body. Early lung cancer often has no symptoms and can only be detected by medical imaging . As the cancer progresses, most people experience nonspecific respiratory problems: coughing , shortness of breath , or chest pain . Other symptoms depend on the location and size of the tumor. Those suspected of having lung cancer typically undergo a series of imaging tests to determine the location and extent of any tumors. Definitive diagnosis of lung cancer requires
9344-753: The body. Different tumors can acquire these abilities through different mutations, though generally cancer-contributing mutations activate oncogenes and inactivate tumor suppressors . Some mutations – called "driver mutations" – are particularly common in adenocarcinomas, and contribute disproportionately to tumor development. These typically occur in the receptor tyrosine kinases EGFR, BRAF, MET, KRAS , and PIK3CA . Similarly, some adenocarcinomas are driven by chromosomal rearrangements that result in overexpression of tyrosine kinases ALK, ROS1, NTRK, and RET. A given tumor will typically have just one driver mutation. In contrast, SCLCs rarely have these driver mutations, and instead often have mutations that have inactivated
9472-534: The cancer's stage based on how far it has spread. Treatment for early stage lung cancer includes surgery to remove the tumor, sometimes followed by radiation therapy and chemotherapy to kill any remaining cancer cells. Later stage cancer is treated with radiation therapy and chemotherapy alongside drug treatments that target specific cancer subtypes. Even with treatment, only around 20% of people survive five years on from their diagnosis. Survival rates are higher in those diagnosed at an earlier stage, diagnosed at
9600-739: The center of the lungs, in the major airways. Their cells appear small with ill-defined boundaries, not much cytoplasm , many mitochondria , and have distinctive nuclei with granular-looking chromatin and no visible nucleoli . NSCLCs comprise a group of three cancer types: adenocarcinoma , squamous-cell carcinoma , and large-cell carcinoma . Nearly 40% of lung cancers are adenocarcinomas. Their cells grow in three-dimensional clumps, resemble glandular cells, and may produce mucin . About 30% of lung cancers are squamous-cell carcinomas. They typically occur close to large airways. The tumors consist of sheets of cells, with layers of keratin . A hollow cavity and associated cell death are commonly found at
9728-438: The center of the tumor. Less than 10% of lung cancers are large-cell carcinomas, so named because the cells are large, with excess cytoplasm, large nuclei, and conspicuous nucleoli . Around 10% of lung cancers are rarer types. These include mixes of the above subtypes like adenosquamous carcinoma , and rare subtypes such as carcinoid tumors , and sarcomatoid carcinomas . Several lung cancer types are subclassified based on
9856-458: The early 1730s, a group of Quakers moved north from Purchase, New York , to settle in present-day Chappaqua. They built their homes on Quaker Road (more recently, Quaker Street; Quaker Road still exists but is no longer in the town center) and held their meetings at the home of Abel Weeks. Their meeting house was built in 1753 and still holds weekly meetings each Sunday. The area around the meeting house, known as Old Chappaqua Historic District ,
9984-491: The elderly into buying products because they were a "guaranteed winner" of a lottery. The settlement required the companies to expand the type size of notices in the packaging that no purchase is necessary to play the sweepstakes, and to: The UK edition of Reader's Digest has also been criticized by the Trading Standards Institute for preying on the elderly and vulnerable with misleading bulk mailings that claim
10112-405: The extent of local spread: with the cancer metastasized to no lymph nodes (N0), pulmonary or hilar nodes (along the bronchi) on the same side as the tumor (N1), mediastinal or subcarinal lymph nodes (in the middle of the lungs, N2), or lymph nodes on the opposite side of the lung from the tumor (N3). Metastases are staged as no metastases (M0), nearby metastases (M1a; the space around the lung or
10240-545: The first two chemotherapy cycles. First-line therapy causes remission in up to 80% of those who receive it; however most people relapse with chemotherapy-resistant disease. Those who relapse are given second-line chemotherapies. Topotecan and lurbinectedin are approved by the US FDA for this purpose. Irinotecan, paclitaxel , docetaxel , vinorelbine , etoposide, and gemcitabine are also sometimes used, and are similarly efficacious. Prophylactic cranial irradiation can reduce
10368-687: The genetic makeup of the cancerous cells. Up to 30% of tumors have mutations in the EGFR gene that result in an overactive EGFR protein; these can be treated with EGFR inhibitors osimertinib , erlotinib , gefitinib , afatinib , or dacomitinib – with osimertinib known to be superior to erlotinib and gefitinib, and all superior to chemotherapy alone. Up to 7% of those with NSCLC harbor mutations that result in hyperactive ALK protein, which can be treated with ALK inhibitors crizotinib , or its successors alectinib , brigatinib , and ceritinib . Those treated with ALK inhibitors who relapse can then be treated with
10496-410: The government of New York decided to split the overly large town of North Castle (jokingly called "the two saddlebags") into two smaller towns, one of which was named New Castle . The border was drawn from the southwest corner of Bedford to the northeast edge of Mount Pleasant . New Castle's borders have remained the same since 1791, except for a small piece of land received from Somers in 1846 and
10624-487: The growth characteristics of the cancer cells. Adenocarcinomas are classified as lepidic (growing along the surface of intact alveolar walls), acinar and papillary , or micropapillary and solid pattern. Lepidic adenocarcinomas tend to be least aggressive, while micropapillary and solid pattern adenocarcinomas are most aggressive. In addition to examining cell morphology, biopsies are often stained by immunohistochemistry to confirm lung cancer classification. SCLCs bear
10752-552: The hamlet of Millwood . Parts of the Chappaqua Central School District include homes in other zip codes, such as 10570, the Pleasantville zip code. Chappaqua is accessible from the Saw Mill River Parkway , which runs through Westchester County. Chappaqua has a vibrant downtown along King Street and South Greeley Avenue. It includes many commercial buildings such as Pizza Station, Little Thai Kitchen,
10880-465: The heart , arrhythmia (irregular heartbeat), and heart failure . About one in three people diagnosed with lung cancer have symptoms caused by metastases in sites other than the lungs. Lung cancer can metastasize anywhere in the body, with different symptoms depending on the location. Brain metastases can cause headache , nausea , vomiting , seizures , and neurological deficits . Bone metastases can cause pain, bone fractures , and compression of
11008-409: The heart, and disseminated intravascular coagulation (clots throughout the body). Paraneoplastic syndromes involving the skin and kidneys are rare, each occurring in up to 1% of those with lung cancer. A person suspected of having lung cancer will have imaging tests done to evaluate the presence, extent, and location of tumors. First, many primary care providers perform a chest X-ray to look for
11136-423: The heart, or the opposite lung), a single distant metastasis (M1b), or multiple metastases (M1c). These T, N, and M scores are combined to designate a stage grouping for the cancer. Cancer limited to smaller tumors is designated stage I. Disease with larger tumors or spread to the nearest lymph nodes is stage II. Cancer with the largest tumors or extensive lymph node spread is stage III. Cancer that has metastasized
11264-494: The issuance of US$ 2.2 billion of debt. Ripplewood invested $ 275 million of its own money, and had partners including Rothschild Bank of Zürich and GoldenTree Asset Management of New York. The private-equity deal tripled the association's interest payments, to $ 148 million a year. On August 24, 2009, RDA announced it had filed with the US Bankruptcy court an arranged Chapter 11 bankruptcy to continue operations, and to restructure
11392-473: The last few days of life, many develop terminal secretions – pooled fluid in the airways that can cause a rattling sound while breathing. This is thought not to cause respiratory problems, but can distress family members and caregivers. Terminal secretions can be reduced by anticholinergic medications . Even those who are non-communicative or have reduced consciousness may be able to experience cancer-related pain, so pain medications are typically continued until
11520-500: The limited stage, meaning cancer is confined to one side of the chest, within the scope of a single radiotherapy field. The other two thirds are diagnosed at the "extensive stage", with cancer spread to both sides of the chest, or to other parts of the body. NSCLC – and sometimes SCLC – is typically staged with the American Joint Committee on Cancer 's Tumor, Node, Metastasis (TNM) staging system . The size and extent of
11648-403: The little-finger side of the arm as well as destruction of the topmost ribs . Swollen lymph nodes above the collarbone can indicate a tumor that has spread within the chest. Tumors obstructing bloodflow to the heart can cause superior vena cava syndrome (swelling of the upper body and shortness of breath), while tumors infiltrating the area around the heart can cause fluid buildup around
11776-1057: The lower levels of radon that seep into residential spaces can increase occupants' risk of lung cancer. Like asbestos, cigarette smoking and radon exposure increase risk synergistically. Radon exposure is responsible for between 3% and 14% of lung cancer cases. Several other chemicals encountered in various occupations are also associated with increased lung cancer risk including arsenic used in wood preservation , pesticide application, and some ore smelting ; ionizing radiation encountered during uranium mining ; vinyl chloride in papermaking ; beryllium in jewelers , ceramics workers, missile technicians, and nuclear reactor workers; chromium in stainless steel production, welding , and hide tanning ; nickel in electroplaters , glass workers, metal workers, welders, and those who make batteries, ceramics, and jewelry; and diesel exhaust encountered by miners. Exposure to air pollution , especially particulate matter released by motor vehicle exhaust and fossil fuel -burning power plants, increases
11904-550: The lung increase one's risk of lung cancer. This association is strongest for chronic obstructive pulmonary disorder – the risk is highest in those with the most inflammation, and reduced in those whose inflammation is treated with inhaled corticosteroids . Other inflammatory lung and immune system diseases such as alpha-1 antitrypsin deficiency , interstitial fibrosis , scleroderma , Chlamydia pneumoniae infection, tuberculosis , and HIV infection are associated with increased risk of developing lung cancer. Epstein–Barr virus
12032-531: The magazine's trade volume. In each market, local editors commission or purchase articles for their own markets and share content with U.S. and other editions. The selected articles are then translated by local translators and the translations edited by the local editors to make them match the "well-educated informal" style of the American edition. Over the 90 years, the company has published editions in various languages in different countries, or for different regions. Often, these editions started out as translations of
12160-508: The magazine, the publisher is especially well known in Germany for the science fiction anthology Unterwegs in die Welt von Morgen ("The Road to Tomorrow"), consisting of 50 hardcover volumes of classic science fiction novels (such as Robert A. Heinlein 's Stranger in a Strange Land , Arthur C. Clarke 's 2001 , or Ray Bradbury 's Fahrenheit 451 , usually two novels per volume) published between 1986 and 1995. More recent book series by
12288-410: The markers of neuroendocrine cells , such as chromogranin , synaptophysin , and CD56 . Adenocarcinomas tend to express Napsin-A and TTF-1 ; squamous cell carcinomas lack Napsin-A and TTF-1 , but express p63 and its cancer-specific isoform p40. CK7 and CK20 are also commonly used to differentiate lung cancers. CK20 is found in several cancers, but typically absent from lung cancer. CK7
12416-421: The mid-20th century, phonograph record albums of popular classical and easy-listening music, bearing the magazine's name, were sold by mail. Reader's Digest also partnered with RCA to offer a mail-order music club which offered discount pricing on vinyl records. In 2001, 32 states' attorneys general reached agreements with the company and other sweepstakes operators to settle allegations that they tricked
12544-512: The most-advanced stage, IVB, have a two-year survival of 10% and a five-year survival of 0%. Five-year survival is higher in women (22%) than men (16%). Women tend to be diagnosed with less-advanced disease, and have better outcomes than men diagnosed at the same stage. Average five-year survival also varies across the world, with particularly high five-year survival in Japan (33%), and five-year survival above 20% in 12 other countries: Mauritius, Canada,
12672-498: The name they heard Native Americans use for their valley and hillside. It was an Algonquian word, shah-pah-ka , and it meant "the rustling land" or "the rattling land," or a place where nothing is heard but the rustling of the wind in the leaves. The Quakers spelled it Shapiqua, Shapaqua, Shapequa, Shappaqua, and, finally, Chappaqua. Their meeting was often referred to as the Shapequa Meeting as early as 1745. On March 18, 1791,
12800-431: The nicotine replacement varenicline as first-line therapies to aid in smoking cessation. Clonidine and nortriptyline are recommended second-line therapies. The majority of those diagnosed with lung cancer attempt to quit smoking; around half succeed. Even after lung cancer diagnosis, smoking cessation improves treatment outcomes, reducing cancer treatment toxicity and failure rates, and lengthening survival time. At
12928-498: The poverty line. 6.6% of people old enough had a high school or equivalent degree of education, 5.8 had some college but no degree, 4% had an associate degree, 37.3% had a bachelor's degree, and 46.3% had a graduate or professional degree. Nationwide, Chappaqua ranks 42nd among the 100 highest-income places in the United States (with at least 1,000 households). In 2008, CNNMoney listed Chappaqua fifth in their list of "25 top-earning towns." Chappaqua 2007 estimated median household income
13056-526: The protein PD-L1 , but are sometimes effective in those that do not. Treatment with pembrolizumab , atezolizumab , or combination nivolumab plus ipilimumab are all superior to chemotherapy alone against tumors expressing PD-L1. Those who relapse on the above are treated with second-line chemotherapeutics docetaxel and ramucirumab . Integrating palliative care (medical care focused on improving symptoms and lessening discomfort) into lung cancer treatment from
13184-465: The publisher include Im Spiegel der Zeit ("Reflections of the Times", a series of recent newspaper or magazine reports) and Klassiker der Weltliteratur ("World Literature Classics"). Chappaqua, New York Chappaqua ( / ˈ tʃ æ p ə k w ɑː / CHAP -ə-kwah ) is a hamlet and census-designated place in the town of New Castle , in northern Westchester County, New York . It
13312-479: The recipient is guaranteed a large cash prize and advising them not to discuss this with anyone else. Following their complaint, the Advertising Standards Authority said they would be launching an investigation. The ASA investigation upheld the complaint in 2008, ruling that the Reader's Digest mailing was irresponsible and misleading (particularly for the elderly) and had breached three clauses of
13440-412: The risk of brain metastases and improve survival in those with limited-stage disease. Extensive-stage SCLC is treated first with etoposide along with either cisplatin or carboplatin. Radiotherapy is used only to shrink tumors that are causing particularly severe symptoms. Combining standard chemotherapy with an immune checkpoint inhibitor can improve survival for a minority of those affected, extending
13568-400: The risk of developing lung cancer as an average person, even after controlling for occupational exposure and smoking habits. Genome-wide association studies have identified many gene variants associated with lung cancer risk, each of which contributes a small risk increase. Many of these genes participate in pathways known to be involved in carcinogenesis, namely DNA repair , inflammation ,
13696-420: The risk of lung cancer. Indoor air pollution from burning wood , charcoal , or crop residue for cooking and heating has also been linked to an increased risk of developing lung cancer. The International Agency for Research on Cancer has classified emission from household burning of coal and biomass as "carcinogenic" and "probably carcinogenic" respectively. Several other diseases that cause inflammation of
13824-455: The risk of someone who smokes and has asbestos exposure dying from lung cancer is much higher than would be expected from adding the two risks together. Similarly, exposure to radon , a naturally occurring breakdown product of the Earth's radioactive elements , is associated with increased lung cancer risk. Radon levels vary with geography. Underground miners have the greatest exposure; however even
13952-413: The same lobe of the lung, or invade the chest wall , diaphragm (or the nerve that controls it ), or area around the heart. Tumors that are larger than 7 cm, have nodules spread in different lobes of a lung, or invade the mediastinum (center of the chest cavity), heart, largest blood vessels that supply the heart, trachea , esophagus , or spine are designated T4. Lymph node staging depends on
14080-673: The secession of Mount Kisco in 1978. Chappaqua had great streams such as the Saw Mill River and Roaring Brook. These bodies of water powered mills to crush corn and press oil from beans. The eastern half of Chappaqua was very suitable for farming. The majority of the Quaker settlers of Chappaqua were farmers. The popular farming industry also helped give way to Chappaqua's high milk production. Other popular industries from Chappaqua included shoes, hardware, vinegar, pickles, eyeglasses, and furniture. Many early homes and businesses were demolished in
14208-480: The table of contents on the front cover. Each article was prefaced by a small, simple line drawing. In more recent times, the format evolved into flashy, colorful, eye-catching graphics throughout, and many short bits of data interspersed with full articles. The table of contents is now contained inside. From 2003 to 2007, the back cover featured "Our America", paintings of Rockwell -style whimsical situations by artist C. F. Payne . Another monthly consumer advice feature
14336-678: The third-generation ALK inhibitor lorlatinib . Up to 5% with NSCLC have overactive MET , which can be inhibited with MET inhibitors capmatinib or tepotinib . Targeted therapies are also available for some cancers with rare mutations. Cancers with hyperactive BRAF (around 2% of NSCLC) can be treated by dabrafenib combined with the MEK inhibitor trametinib ; those with activated ROS1 (around 1% of NSCLC) can be inhibited by crizotinib, lorlatinib, or entrectinib ; overactive NTRK (<1% of NSCLC) by entrectinib or larotrectinib ; active RET (around 1% of NSCLC) by selpercatinib . People whose NSCLC
14464-442: The time of death. Around 19% of people diagnosed with lung cancer survive five years from diagnosis , though prognosis varies based on the stage of the disease at diagnosis and the type of lung cancer. Prognosis is better for people with lung cancer diagnosed at an earlier stage; those diagnosed at the earliest TNM stage, IA1 (small tumor, no spread), have a two-year survival of 97% and five-year survival of 92%. Those diagnosed at
14592-419: The time of diagnosis improves the survival time and quality of life of those with lung cancer. Particularly common symptoms of lung cancer are shortness of breath and pain. Supplemental oxygen, improved airflow, re-orienting an affected person in bed, and low-dose morphine can all improve shortness of breath. In around 20 to 30% of those with lung cancer – particularly those with late-stage disease – growth of
14720-443: The time of relapse. Those with limited stage SCLC that go into complete remission after chemotherapy and radiotherapy have a 50% chance of brain metastases developing within the next two years – a chance reduced by prophylactic cranial irradiation. Several other personal and disease factors are associated with improved outcomes. Those diagnosed at a younger age tend to have better outcomes. Those who smoke or experience weight loss as
14848-531: The tumor (T), spread to regional lymph nodes (N), and distant metastases (M) are scored individually, and combined to form stage groups. Relatively small tumors are designated T1, which are subdivided by size: tumors ≤ 1 centimeter (cm) across are T1a; 1–2 cm T1b; 2–3 cm T1c. Tumors up to 5 cm across, or those that have spread to the visceral pleura (tissue covering the lung) or main bronchi , are designated T2. T2a designates 3–4 cm tumors; T2b 4–5 cm tumors. T3 tumors are up to 7 cm across, have multiple nodules in
14976-494: The tumor can narrow or block the airway , causing coughing and difficulty breathing. Obstructing tumors can be surgically removed where possible, though typically those with airway obstruction are not well enough for surgery. In such cases the American College of Chest Physicians recommends opening the airway by inserting a stent , attempting to shrink the tumor with localized radiation ( brachytherapy ), or physically removing
15104-1309: The tumor site(s) or nerve damage. The World Health Organization (WHO) has developed a three-tiered system for managing cancer pain. For those with mild pain (tier one), the WHO recommends acetominophen or a nonsteroidal anti-inflammatory drug . Around a third of people experience moderate (tier two) or severe (tier three) pain, for which the WHO recommends opioid painkillers. Opioids are typically effective at easing nociceptive pain (pain caused by damage to various body tissues). Opioids are occasionally effective at easing neuropathic pain (pain caused by nerve damage). Neuropathic agents such as anticonvulsants , tricyclic antidepressants , and serotonin–norepinephrine reuptake inhibitors , are often used to ease neuropathic pain, either alone or in combination with opioids. In many cases, targeted radiotherapy can be used to shrink tumors, reducing pain and other symptoms caused by tumor growth. Individuals who have advanced disease and are approaching end-of-life can benefit from dedicated end-of-life care to manage symptoms and ease suffering. As in earlier disease, pain and difficulty breathing are common, and can be managed with opioid pain medications, transitioning from oral medication to injected medication if
15232-529: The tumor suppressors p53 and RB . A cluster of tumor suppressor genes on the short arm of chromosome 3 are often lost early in the development of all lung cancers. Those who smoke can reduce their lung cancer risk by quitting smoking – the risk reduction is greater the longer a person goes without smoking. Self-help programs tend to have little influence on success of smoking cessation, whereas combined counseling and pharmacotherapy improve cessation rates. The US FDA has approved antidepressant therapies and
15360-478: The tumors can be successfully treated and result in decreased mortality. There is evidence that regular low-dose CT scans in people at high risk of developing lung cancer reduces total lung cancer deaths by as much as 20%. Despite evidence of benefit in these populations, potential harms of screening include the potential for a person to have a 'false positive' screening result that may lead to unnecessary testing, invasive procedures, and distress. Although rare, there
15488-417: The type of cells the tumor is derived from; tumors derived from different cells progress and respond to treatment differently. There are two main types of lung cancer, categorized by the size and appearance of the malignant cells seen by a histopathologist under a microscope : small cell lung cancer (SCLC; 15% of cases) and non-small-cell lung cancer (NSCLC; 85% of cases). SCLC tumors are often found near
15616-411: The year 1885 the school caught fire, and much refurbishing was done, with the addition of two new wings. It was sold in 1908 and the school's property is now owned by Children's Aid . Emergency medical services and fire protection are provided by volunteer agencies. The Chappaqua Volunteer Ambulance Corps provides basic life support services to most of New Castle, including Chappaqua. Paramedic service
15744-420: Was $ 198,000. Although Chappaqua's crime rate is far below the national average, the area has had a few high-profile murders. In 1996, a battle between a lottery winner and his former lover over custody of their 5-year-old child resulted in a gun battle; the winner was acquitted of the murder of his former lover on the basis of self-defense, and convicted of the shooting of the woman's father. In November 2006
15872-453: Was a rare disease. In the 1950s and 1960s, increasing evidence linked lung cancer and tobacco use, culminating in declarations by most large national health bodies discouraging tobacco use. Early lung cancer often has no symptoms. When symptoms do arise they are often nonspecific respiratory problems – coughing , shortness of breath , or chest pain – that can differ from person to person. Those who experience coughing tend to report either
16000-622: Was added to the National Register of Historic Places in 1974. Horace Greeley 's home, known as Rehoboth and built by Greeley himself, still stands in Chappaqua. It is also listed on the National Register of Historic Places along with Chappaqua Railroad Depot and Depot Plaza , Church of Saint Mary the Virgin and Greeley Grove , and the Greeley House . Various spellings were used for
16128-444: Was built in 1957. The three elementary schools in Chappaqua were completed over a twenty-year period: Roaring Brook School in 1951, Douglas G. Grafflin in 1962, and Westorchard in 1971. In 2003, after the opening of the new middle school, Seven Bridges, and the moving of the fifth grade from Chappaqua's elementary schools to the middle schools, the district added a full day kindergarten. In 2024, Chappaqua Central School District
16256-558: Was convicted October 4, 2008 for the murder of his wife, Peggy Perez-Olivo, who had been working as a teaching assistant at Douglas Grafflin Elementary School in Chappaqua. A Georgian-inspired mansion in Chappaqua served as the shooting location for the 2022 horror film Bodies Bodies Bodies . Chappaqua downtown includes a farmer's market near the Saw Mill River Pkwy. It boasts a variety of local vegetables and fruits and
16384-593: Was ranked as the 17th best public school district in New York State. Schools currently operating in Chappaqua include: Small, one-room schoolhouses devoid of windows were prevalent in the 1800s. In the Chappaqua region, there were eight such schoolhouses. These small schools prevailed until around 1870, when the Quakers built a large school called the Chappaqua Mountain Institute on Quaker Street. In
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