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Maoam is a brand of sweets produced by the German confectionery company Haribo . The product name is a century old. The product consists of chewy fruit-flavoured candy in various flavours. A packet of Maoam sweets usually includes five pieces of a particular flavour, and several of these packets are stacked into a stick which is then sold. The sweets are also available in larger packages. Maoam sweets contain gelatine.

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81-486: Edmund Münster took over the "Düsseldorfer Lakritzenwerk" in 1900. The company primarily produced liquorice candy until the 1930s; in 1930 or 1931 Münster acquired a licence from abroad to produce a chewy fruity candy under the name "Maoam". The name of the product is an invention, and the abbreviation of " Mundet allen ohne Ausnahme " ( They taste good to everyone, without exception , in German). In August 1930 Münster received

162-432: A healthy diet . If lifestyle changes are not sufficient, blood pressure medications are used. Up to three medications taken concurrently can control blood pressure in 90% of people. The treatment of moderately high arterial blood pressure (defined as >160/100 mmHg) with medications is associated with an improved life expectancy . The effect of treatment of blood pressure between 130/80 mmHg and 160/100 mmHg

243-412: A western diet and lifestyle, and the risk of becoming hypertensive in later life is substantial in most such societies. Several environmental or lifestyle factors influence blood pressure. Reducing dietary salt intake lowers blood pressure; as does weight loss, exercise training, vegetarian diets, increased dietary potassium intake and high dietary calcium supplementation. Increasing alcohol intake

324-561: A " utility model for the product Maoam, a chewy candy without chewing gum, made of sugar, syrup and other ingredients" from Düsseldorf. The model covers the name Maoam, the product, the package and any imitation made of liquorice, cocoa, sugar or bakery products. Edmund Münster GmbH & Co. started producing the candy, which was wrapped in wax paper. Maoam sales began on Easter 1931 in characteristic Maoam palindrome and ambigram logo . The packaging has only changed slightly to this day. Imitations of these chewy candies began to appear, which

405-469: A clearly identifiable cause, such as chronic kidney disease , narrowing of the kidney arteries , an endocrine disorder , or the use of birth control pills . Blood pressure is classified by two measurements, the systolic (first number) and diastolic (second number) pressures. For most adults, normal blood pressure at rest is within the range of 100–140 millimeters mercury (mmHg) systolic and 60–90 mmHg diastolic. For most adults, high blood pressure

486-511: A complex interaction of genes and environmental factors. More than 2000 common genetic variants with small effects on blood pressure have been identified in association with high blood pressure, as well as some rare genetic variants with large effects on blood pressure. There is also evidence that DNA methylation at multiple nearby CpG sites may link some sequence variation to blood pressure, possibly via effects on vascular or renal function. Blood pressure rises with aging in societies with

567-925: A decrease in SBP by 5-15mmHg, versus resistance training showing a decrease of only 3-5mmHg. Aerobic exercises such as jogging, rowing, dancing, or hiking can decrease SBP the greatest. The decrease in SBP can regulate the effect of hypertension ensuring the baby will not be harmed. Resistance training takes a toll on the cardiovascular system in untrained individuals, leading to a reluctance in prescription of resistance training for hypertensive reduction purposes. Failure to thrive , seizures , irritability , lack of energy , and difficulty in breathing can be associated with hypertension in newborns and young infants. In older infants and children, hypertension can cause headache, unexplained irritability, fatigue , failure to thrive, blurred vision , nosebleeds , and facial paralysis . Primary (also termed essential) hypertension results from

648-438: A decreased blood pressure in the lower extremities relative to the arms, or delayed or absent femoral arterial pulses . Pheochromocytoma may cause abrupt episodes of hypertension accompanied by headache, palpitations , pale appearance , and excessive sweating . Severely elevated blood pressure (equal to or greater than a systolic 180 mmHg or diastolic of 120 mmHg) is referred to as a hypertensive crisis. Hypertensive crisis

729-450: A distinctive flavour that blends readily with the natural and imitation flavouring components employed in the tobacco industry. Liquorice can also be added to cigarette rolling papers . As of 2009 , the US Food and Drug Administration banned the use of any "characterizing flavors" other than menthol from cigarettes, but not other manufactured tobacco products. Liquorice flavour is found in

810-551: A flat surface at the level of the heart. Blood pressure measurement should be done in a quiet room so the medical professional checking the blood pressure can hear the Korotkoff sounds while listening to the brachial artery with a stethoscope for accurate blood pressure measurements. The blood pressure cuff should be deflated slowly (2–3 mmHg per second) while listening for the Korotkoff sounds. The bladder should be emptied before

891-426: A guy dances bizarrely. Liquorice Liquorice ( Commonwealth English ) or licorice ( American English ; see spelling differences ; IPA : / ˈ l ɪ k ər ɪ ʃ , - ɪ s / LIK -ər-ish, -⁠iss ) is the common name of Glycyrrhiza glabra , a flowering plant of the bean family Fabaceae , from the root of which a sweet, aromatic flavouring is extracted . The liquorice plant

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972-416: A hump of fat behind the neck and shoulders (referred to as a buffalo hump), and purple abdominal stretch marks . Hyperthyroidism frequently causes weight loss with increased appetite, fast heart rate , bulging eyes , and tremor. Renal artery stenosis may be associated with a localized abdominal bruit to the left or right of the midline, or in both locations. Coarctation of the aorta frequently causes

1053-648: A key component of liquorice) can lead to undesirable consequences. Clinically, it is suspected that overindulgence in liquorice may manifest as unexplained hypertension , low blood potassium levels ( hypokalemia ), and muscle weakness in individuals. Consuming liquorice should be avoided during pregnancy. The word liquorice , or licorice , is derived via the Anglo-French lycorys , from Late Latin liquiritia , itself ultimately derived from Greek γλυκύρριζα , glykyrrhiza (the Modern Greek spelling of

1134-414: A person's blood pressure is measured since this can increase blood pressure by up to 15/10 mmHg. Multiple blood pressure readings (at least two) spaced 1–2 minutes apart should be obtained to ensure accuracy. Ambulatory blood pressure monitoring over 12 to 24 hours is the most accurate method to confirm the diagnosis. An exception to this is those with very high blood pressure readings especially when there

1215-439: A prior minor disturbance such as a silent heart attack. Blood pressure measurements can be influenced by circumstances of measurement. Guidelines use different thresholds for office (also known as clinic), home (when the patient measures their own blood pressure at home), and ambulatory blood pressure (using an automated device over a 24-hour period). Hypertension occurs in around 0.2 to 3% of newborns; however, blood pressure

1296-439: A related species G. uralensis (often translated as "liquorice") is known as gancao ( Chinese : 甘草 ; lit. 'sweet grass'), and is believed to "harmonize" the ingredients in a formula. although there is no high-quality clinical research to indicate it is safe or effective for any medicinal purpose. The European Medical Agency added liquorice to their list of herbal medicine. The essential oils inhibit

1377-616: A specific level of intake is safe or unsafe. The effects of excessive liquorice consumption on lowering potassium levels in the blood and increasing blood pressure are a particular concern for people with hypertension (high blood pressure) or heart or kidney disease. Some adverse effects of liquorice consumed in amounts of 50 to 200 g per day over four weeks appear to be caused by glycyrrhizic acid (75 to 540 mg per day glycyrrhetinic acid) causing increases in blood pressure. Consuming large amounts of liquorice during pregnancy has been associated with premature birth and health problems in

1458-458: A wide variety of candies or sweets . In most of these candies, the taste is reinforced by aniseed oil so the actual content of liquorice is low. In the Netherlands, liquorice confectionery ( drop ) is a common sweet sold in many forms. Mixing it with mint , menthol , aniseed , or laurel is common. It is also mixed with ammonium chloride ( salmiak ); salmiak liquorice in the Netherlands

1539-411: Is "Was wollt ihr denn?!" ( German for "What do you want?!"). In the advertisements, a group of people are asked what they want next, for example the audience at a football match or at a large television broadcast. The people are always given two options (for example "Do you want extra time?" - "Do you want a penalty shootout?") After both options have been answered with a loud "No!", the follow-up question

1620-448: Is "What do you want then?", which the audience answers with a loud cry of "Maoam, Maoam..." The football referee Walter Eschweiler used to star in these advertisements. The former volleyball Bundesliga champion VC Eintracht Mendig  [ de ] changed their name to Maoam Mendig per sponsorship from 2003 to 2005. In 2016 Maoam launched the "Full on till its gone" campaign in UK where

1701-435: Is a hypertensive emergency and has several serious complications including vision loss , brain swelling , seizures , kidney failure , pulmonary edema , and disseminated intravascular coagulation (a blood clotting disorder). In contrast, gestational hypertension is defined as new-onset hypertension during pregnancy without protein in the urine. There have been significant findings on how exercising can help reduce

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1782-464: Is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major risk factor for stroke , coronary artery disease , heart failure , atrial fibrillation , peripheral arterial disease , vision loss , chronic kidney disease , and dementia . Hypertension is a major cause of premature death worldwide. High blood pressure

1863-507: Is a component of syndrome X (or metabolic syndrome ), can cause hyperuricemia and gout and is also associated with elevated blood pressure. Events in early life, such as low birth weight , maternal smoking , and lack of breastfeeding may be risk factors for adult essential hypertension, although strength of the relationships is weak and the mechanisms linking these exposures to adult hypertension remain unclear. Secondary hypertension results from an identifiable cause. Kidney disease

1944-516: Is a form of salt -sensitive hypertension, where sodium intake does not modulate either adrenal or renal vascular responses to angiotensin II . They make up 25% of the hypertensive population. Hypertension is diagnosed on the basis of a persistently high resting blood pressure. Elevated blood pressure measurements on at least two separate occasions is required for a diagnosis of hypertension. For an accurate diagnosis of hypertension to be made, it

2025-493: Is abnormally high, but diastolic pressure may be normal or low, a condition termed isolated systolic hypertension . The high pulse pressure in elderly people with hypertension or isolated systolic hypertension is explained by increased arterial stiffness , which typically accompanies aging and may be exacerbated by high blood pressure. Many mechanisms have been proposed to account for the rise in peripheral resistance in hypertension. Most evidence implicates either disturbances in

2106-473: Is also associated with decreased peripheral venous compliance , which may increase venous return , increase cardiac preload and, ultimately, cause diastolic dysfunction . For patients having hypertension, higher heart rate variability (HRV) is a risk factor for atrial fibrillation . Pulse pressure (the difference between systolic and diastolic blood pressure) is frequently increased in older people with hypertension. This can mean that systolic pressure

2187-445: Is an herbaceous perennial legume native to West Asia , North Africa , and Southern Europe . Liquorice is used as a flavouring in confectionery, tobacco , beverages, and pharmaceuticals , and is marketed as a dietary supplement . Liquorice extracts have been used in herbalism and traditional medicine . Excessive consumption of liquorice (more than 2 mg/kg [0.91 mg/lb] per day of pure glycyrrhizinic acid ,

2268-421: Is an oblong pod , 20–30 mm ( 3 ⁄ 4 – 1 + 1 ⁄ 8  in) long, containing several seeds . The roots are stoloniferous . Liquorice root contains triterpenoids , polyphenols , and polysaccharides . Flavonoids account for the yellow root color. The principal glycoside , glycyrrhizin, exists in content of 7% to 10%, depending on cultivation practices. The isoflavene glabrene and

2349-403: Is associated with elevated blood pressure. Air pollution is associated with hypertension. Whether these associations are causal is unknown. Gout and elevated blood uric acid are associated with hypertension and evidence from genetic ( Mendelian Randomization) studies and clinical trials indicate this relationship is likely to be causal. Insulin resistance , which is common in obesity and

2430-424: Is associated with higher blood pressure, but the possible roles of other factors such as caffeine consumption, and vitamin D deficiency are less clear. Average blood pressure is higher in the winter than in the summer. Depression is associated with hypertension and loneliness is also a risk factor. Periodontal disease is also associated with high blood pressure. Arsenic exposure through drinking water

2511-419: Is being measured to sit quietly for at least five minutes which is then followed by application of a properly fitted blood pressure cuff to a bare upper arm. The person should be seated with their back supported, feet flat on the floor, and with their legs uncrossed. The person whose blood pressure is being measured should avoid talking or moving during this process. The arm being measured should be supported on

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2592-519: Is categorized as either hypertensive urgency or hypertensive emergency , according to the absence or presence of end organ damage, respectively. In hypertensive urgency, there is no evidence of end organ damage resulting from the elevated blood pressure. In these cases, oral medications are used to lower the BP gradually over 24 to 48 hours. In hypertensive emergency, there is evidence of direct damage to one or more organs. The most affected organs include

2673-462: Is classified as primary (essential) hypertension or secondary hypertension . About 90–95% of cases are primary, defined as high blood pressure due to nonspecific lifestyle and genetic factors. Lifestyle factors that increase the risk include excess salt in the diet, excess body weight , smoking , physical inactivity and alcohol use. The remaining 5–10% of cases are categorized as secondary hypertension, defined as high blood pressure due to

2754-446: Is considerable evidence that reducing dietary salt intake lowers blood pressure , but whether this translates into a reduction in mortality and cardiovascular disease remains uncertain. Estimated sodium intake ≥6 g/day and <3 g/day are both associated with high risk of death or major cardiovascular disease, but the association between high sodium intake and adverse outcomes is only observed in people with hypertension. Consequently, in

2835-418: Is considered safe as a food ingredient, glycyrrhizin can cause serious side effects if consumed in large amounts (above 0.2 mg per kg per day). One estimate is that a normal healthy person can consume 10 mg (0.15 grains) of glycyrrhizic acid per day. Because the composition of liquorice extracts in various products may exist in a broad range, there is not enough scientific information to determine that

2916-568: Is consumed as a cold beverage, especially in Ramadan. In southeastern Turkey, such as in Diyarbakır , licorice root is traditionally made into a chilled beverage that is most commonly consumed in summer. Properties of glycyrrhizin are under preliminary research, such as for hepatitis C or topical treatment of psoriasis , but the low quality of studies as of 2017 prevents conclusions about efficacy and safety. In traditional Chinese medicine ,

2997-435: Is defined as an average systolic or diastolic blood pressure on three or more occasions equal or higher than the 95th percentile appropriate for the sex, age and height of the child. High blood pressure must be confirmed on repeated visits however before characterizing a child as having hypertension. In adolescents, it has been proposed that hypertension is diagnosed and classified using the same criteria as in adults. Much of

3078-399: Is essential for proper blood pressure measurement technique to be used. Improper measurement of blood pressure is common and can change the blood pressure reading by up to 10 mmHg, which can lead to misdiagnosis and misclassification of hypertension. Correct blood pressure measurement technique involves several steps. Proper blood pressure measurement requires the person whose blood pressure

3159-408: Is harvested in the autumn two to three years after planting. Countries producing liquorice include Turkey, Greece, Iran, and Iraq. Liquorice is used as a flavouring agent for tobacco , for flavour-enhancing and moistening agents in the manufacture of American blend cigarettes , moist snuff , chewing tobacco , and pipe tobacco . Liquorice provides tobacco products with a natural sweetness and

3240-640: Is known as zoute drop (' salty liquorice '). Strong, salty sweets are also consumed in Nordic countries where liquorice flavoured alcohols are sold, particularly in Denmark and Finland. Dried sticks of the liquorice root are a traditional confectionery in the Netherlands as were they once in Britain. They were sold simply as sticks of zoethout ('sweet wood') to chew on as a candy. Pontefract in Yorkshire , England,

3321-479: Is less clear, with some reviews finding benefit and others finding unclear benefit. High blood pressure affects 33% of the population globally. About half of all people with high blood pressure do not know that they have it. In 2019, high blood pressure was believed to have been a factor in 19% of all deaths (10.4 million globally). Hypertension is rarely accompanied by symptoms . Half of all people with hypertension are unaware that they have it. Hypertension

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3402-434: Is lifestyle changes, including dietary changes, physical activity, and weight loss. Though these have all been recommended in scientific advisories, a Cochrane systematic review found no evidence (due to lack of data) for effects of weight loss diets on death, long-term complications or adverse events in persons with hypertension. The review did find a decrease in body weight and blood pressure. Their potential effectiveness

3483-407: Is more common in preadolescent children, with most cases caused by kidney disease . Primary or essential hypertension is more common in adolescents and adults and has multiple risk factors, including obesity and a family history of hypertension. Initial assessment upon diagnosis of hypertension should include a complete history and physical examination . The World Health Organization suggests

3564-521: Is not measured routinely in healthy newborns. Hypertension is more common in high risk newborns. A variety of factors, such as gestational age , postconceptional age and birth weight needs to be taken into account when deciding if a blood pressure is normal in a newborn. Hypertension defined as elevated blood pressure over several visits affects 1% to 5% of children and adolescents and is associated with long-term risks of ill-health. Blood pressure rises with age in childhood and, in children, hypertension

3645-485: Is poor organ function. With the availability of 24-hour ambulatory blood pressure monitors and home blood pressure machines, the importance of not wrongly diagnosing those who have white coat hypertension has led to a change in protocols. In the United Kingdom, current best practice is to follow up a single raised clinic reading with ambulatory measurement, or less ideally with home blood pressure monitoring over

3726-492: Is present if the resting blood pressure is persistently at or above 130/80 or 140/90 mmHg. Different numbers apply to children. Ambulatory blood pressure monitoring over a 24-hour period appears more accurate than office-based blood pressure measurement . Lifestyle changes and medications can lower blood pressure and decrease the risk of health complications. Lifestyle changes include weight loss , physical exercise , decreased salt intake , reducing alcohol intake , and

3807-557: Is similar to and at times exceeds a single medication. If hypertension is high enough to justify immediate use of medications, lifestyle changes are still recommended in conjunction with medication. Dietary changes shown to reduce blood pressure include diets with low sodium, the DASH diet (Dietary Approaches to Stop Hypertension), which was the best against 11 other diet in an umbrella review, and plant-based diets. A 2024 clinical guideline recommended an increase dietary fiber intake, with

3888-482: Is spelled 'liquorice' in most of the Commonwealth , but 'licorice' is also used in some countries. Liquorice is a herbaceous perennial , growing to 1 metre (40 in) in height, with pinnate leaves about 7–15 cm (3–6 in) long, with 9–17 leaflets. The flowers are 8–12 mm ( 5 ⁄ 16 – 1 ⁄ 2  in) long, purple to pale whitish blue, produced in a loose inflorescence . The fruit

3969-463: Is the most common secondary cause of hypertension. Hypertension can also be caused by endocrine conditions, such as Cushing's syndrome , hyperthyroidism , hypothyroidism , acromegaly , Conn's syndrome or hyperaldosteronism , renal artery stenosis (from atherosclerosis or fibromuscular dysplasia ), hyperparathyroidism , and pheochromocytoma . Other causes of secondary hypertension include obesity , sleep apnea , pregnancy , coarctation of

4050-429: Is typical of all people who ultimately develop hypertension is disputed. The increased peripheral resistance in established hypertension is mainly attributable to structural narrowing of small arteries and arterioles , although a reduction in the number or density of capillaries may also contribute. It is not clear whether or not vasoconstriction of arteriolar blood vessels plays a role in hypertension. Hypertension

4131-399: Is used as a secondary indicator of kidney disease. Lipid panel and glucose tests are done to identify comorbidities such as diabetes and hyperlipidemia and for cardiovascular risk stratification. Electrocardiogram (EKG/ECG) testing is done to check for evidence that the heart is under strain from high blood pressure, such as thickening of the heart muscle or whether the heart has experienced

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4212-492: Is usually identified as part of health screening or when seeking healthcare for an unrelated problem. Some people with high blood pressure report headaches , as well as lightheadedness , vertigo , tinnitus (buzzing or hissing in the ears), altered vision or fainting episodes . These symptoms, however, might be related to associated anxiety rather than the high blood pressure itself. Long-standing untreated hypertension can cause organ damage with signs such as changes in

4293-403: Is when blood pressure increases upon standing. Once the diagnosis of hypertension has been made, further testing may be performed to find secondary hypertension , identify comorbidities such as diabetes , identify hypertension-caused organ damage such as chronic kidney disease or thickening of the heart muscle , and for cardiovascular disease risk stratification. Secondary hypertension

4374-399: Is where liquorice mixed with sugar began to be used as a sweet in the contemporary way. Pontefract cakes were originally made there. In Cumbria, County Durham, Yorkshire and Lancashire, it is colloquially known as 'Spanish', supposedly because Spanish monks grew liquorice root at Rievaulx Abbey near Thirsk . In Italy, Spain and France, liquorice is used in its natural form. The root of

4455-725: The National Heart, Lung, and Blood Institute and American Academy of Pediatrics made a similar recommendation. However, the American Academy of Family Physicians supports the view of the U.S. Preventive Services Task Force that the available evidence is insufficient to determine the balance of benefits and harms of screening for hypertension in children and adolescents who do not have symptoms. The US Preventive Services Task Force recommends screening adults 18 years or older for hypertension with office blood pressure measurement. According to one review published in 2003, reduction of

4536-432: The blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischemic heart disease by 21%, and reduce the likelihood of dementia , heart failure , and mortality from cardiovascular disease . Various expert groups have produced guidelines regarding how low the blood pressure target should be when a person is treated for hypertension. These groups recommend a target below the range 140–160 / 90–100 mmHg for

4617-559: The optic fundus seen by ophthalmoscopy . The severity of hypertensive retinopathy correlates roughly with the duration or the severity of the hypertension. Other hypertension-caused organ damage include chronic kidney disease and thickening of the heart muscle . Secondary hypertension is hypertension due to an identifiable cause, and may result in certain specific additional signs and symptoms. For example, as well as causing high blood pressure, Cushing's syndrome frequently causes truncal obesity , glucose intolerance , moon face ,

4698-452: The 2017 American Heart Association guidelines recommend medications if the systolic blood pressure is >140 mmHg or if the diastolic BP is >90 mmHg. For people who have experienced cardiovascular disease or those who are at a 10-year risk of cardiovascular disease of greater than 10%, it recommends medications if the systolic blood pressure is >130 mmHg or if the diastolic BP is >80 mmHg. The first line of treatment for hypertension

4779-583: The absence of results from randomized controlled trials, the wisdom of reducing levels of dietary sodium intake below 3 g/day has been questioned. ESC guidelines mention periodontitis is associated with poor cardiovascular health status. The value of routine screening for hypertension is debated. In 2004, the National High Blood Pressure Education Program recommended that children aged 3 years and older have blood pressure measurement at least once at every health care visit and

4860-459: The aorta , excessive eating of liquorice , excessive drinking of alcohol, certain prescription medicines, herbal remedies, and stimulants such as cocaine and methamphetamine . A 2018 review found that any alcohol increased blood pressure in males while over one or two drinks increased the risk in females. In most people with established essential hypertension , increased resistance to blood flow ( total peripheral resistance ) accounts for

4941-464: The body. Through regular bouts of physical activity, blood pressure can reduce the incidence of hypertension. Aerobic exercise has been shown to regulate blood pressure more effectively than resistance training. It is recommended to see the effects of exercising, that a person should aim for 5-7 days/ week of aerobic exercise. This type of exercise should have an intensity of light to moderate, utilizing ~85% of max heart rate (220-age). Aerobic has shown

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5022-890: The brain, kidney, heart and lungs, producing symptoms which may include confusion , drowsiness, chest pain and breathlessness. In hypertensive emergency, the blood pressure must be reduced more rapidly to stop ongoing organ damage; however, there is a lack of randomized controlled trial evidence for this approach. Hypertension occurs in approximately 8–10% of pregnancies. Two blood pressure measurements six hours apart of greater than 140/90 mmHg are diagnostic of hypertension in pregnancy. High blood pressure in pregnancy can be classified as pre-existing hypertension, gestational hypertension , or pre-eclampsia . Women who have chronic hypertension before their pregnancy are at increased risk of complications such as premature birth , low birthweight or stillbirth . Women who have high blood pressure and had complications in their pregnancy have three times

5103-544: The child. Hyper- mineralocorticosteroid syndrome can occur when the body retains sodium, and loses potassium, altering biochemical and hormonal regulation. Some of these activities may include raised aldosterone levels, decline of the renin-angiotensin system and increased levels of the atrial natriuretic hormone in order to compensate the variations in homoeostasis. Other adverse effects may include electrolyte imbalance , edema , increased blood pressure , weight gain, heart problems, and weakness. Symptoms depend on

5184-499: The course of 7 days. The United States Preventive Services Task Force also recommends getting measurements outside of the healthcare environment. Pseudohypertension in the elderly or noncompressibility artery syndrome may also require consideration. This condition is believed to be due to calcification of the arteries resulting in abnormally high blood pressure readings with a blood pressure cuff while intra arterial measurements of blood pressure are normal. Orthostatic hypertension

5265-600: The disease burden of high blood pressure is experienced by people who are not labeled as hypertensive. Consequently, population strategies are required to reduce the consequences of high blood pressure and reduce the need for antihypertensive medications. Lifestyle changes are recommended to lower blood pressure. Recommended lifestyle changes for the prevention of hypertension include: Effective lifestyle modification may lower blood pressure as much as an individual antihypertensive medication. Combinations of two or more lifestyle modifications can achieve even better results. There

5346-565: The effects of hypertension just after one bout of exercise. Exercising can help reduce hypertension as well as pre-eclampsia and eclampsia. The acute physiological responses include an increase in cardiac output (CO) of the individual (increased heart rate and stroke volume). This increase in CO can inadvertently maintain the amount of blood going into the muscles, improving functionality of the muscle later. Exercising can also improve systolic and diastolic blood pressure making it easier for blood to pump to

5427-509: The following initial tests: serum electrolytes , serum creatinine , lipid panel , HbA1c or fasting glucose , urine dipstick and electrocardiogram (ECG/EKG). Serum creatinine is measured to assess for the presence of kidney disease, which can be either the cause or the result of hypertension. eGFR can also provide a baseline measurement of kidney function that can be used to monitor for side effects of certain anti-hypertensive drugs on kidney function. Testing of urine samples for protein

5508-422: The general population. Cochrane reviews recommend similar targets for subgroups such as people with diabetes and people with prior cardiovascular disease. Additionally, Cochrane reviews have found that for older individuals with moderate to high cardiovascular risk, the benefits of trying to achieve a lower than standard blood pressure target (at or below 140/90 mmHg) are outweighed by the risk associated with

5589-425: The genus is γλυκόριζα , glykoriza ) literally meaning 'sweet root' and referring to Glycyrrhiza glabra . The latter gives the plant binomial name with glabra meaning smooth and referring to the plant's smooth husks; the former came to being via the influence of liquere , 'to become fluid', reflecting the method of extracting the sweet component from the roots. As of 2021 , its English common name

5670-518: The growth of Aspergillus flavus . The United States Food and Drug Administration regards that foods containing liquorice and its derivatives (including glycyrrhizin) are generally recognized as safe for use as a food ingredient , if not consumed excessively. Other jurisdictions have suggested no more than 100–200 mg (1.5–3.1 grains) of glycyrrhizin per day, the equivalent of about 70–150 g ( 2 + 1 ⁄ 2 – 5 + 1 ⁄ 4  oz) of liquorice confectionery. Although liquorice

5751-478: The high pressure while cardiac output remains normal. There is evidence that some younger people with prehypertension or 'borderline hypertension' have high cardiac output, an elevated heart rate and normal peripheral resistance, termed hyperkinetic borderline hypertension. These individuals may develop the typical features of established essential hypertension in later life as their cardiac output falls and peripheral resistance rises with age. Whether this pattern

5832-540: The intervention. These findings may not be applicable to other populations. Many expert groups recommend a slightly higher target of 150/90 mmHg for those over somewhere between 60 and 80 years of age. The JNC 8 and American College of Physicians recommend the target of 150/90 mmHg for those over 60 years of age, but some experts within these groups disagree with this recommendation. Some expert groups have also recommended slightly lower targets in those with diabetes or chronic kidney disease , but others recommend

5913-501: The isoflavane glabridin , found in the roots of liquorice, are phytoestrogens . The scent of liquorice root comes from a complex and variable combination of compounds, of which anethole is some 3% of total volatiles. Much of the sweetness in liquorice comes from glycyrrhizin, which has 30–50 times the sweetness of sugar . The sweetness is different from sugar, being less instant, tart, and lasting longer. Liquorice grows best in well-drained soils in deep valleys with full sun. It

5994-550: The kidneys' salt and water handling (particularly abnormalities in the intrarenal renin–angiotensin system ) or abnormalities of the sympathetic nervous system . These mechanisms are not mutually exclusive and it is likely that both contribute to some extent in most cases of essential hypertension. It has also been suggested that endothelial dysfunction and vascular inflammation may also contribute to increased peripheral resistance and vascular damage in hypertension. Interleukin 17 has garnered interest for its role in increasing

6075-516: The plant is simply harvested, washed, dried, and chewed as a mouth freshener. Throughout Italy, unsweetened liquorice is consumed in the form of small black pieces made only from 100% pure liquorice extract. In Calabria , a liqueur is made from pure liquorice extract and in Reggio Emilia a soft drink called acqua d'orcio is made. In some parts of the Arab world, including Syria, Egypt, and Palestine, it

6156-436: The production of several other immune system chemical signals thought to be involved in hypertension such as tumor necrosis factor alpha , interleukin 1 , interleukin 6 , and interleukin 8 . Excessive sodium or insufficient potassium in the diet leads to excessive intracellular sodium, which contracts vascular smooth muscle, restricting blood flow and so increases blood pressure. Non-modulating essential hypertension

6237-406: The risk of death of the baby around the time of birth . Usually there are no symptoms in pre-eclampsia and it is detected by routine screening. When symptoms of pre-eclampsia occur the most common are headache, visual disturbance (often "flashing lights"), vomiting, pain over the stomach, and swelling . Pre-eclampsia can occasionally progress to a life-threatening condition called eclampsia , which

6318-457: The risk of developing cardiovascular disease compared to women with normal blood pressure who had no complications in pregnancy. Pre-eclampsia is a serious condition of the second half of pregnancy and following delivery characterised by increased blood pressure and the presence of protein in the urine . It occurs in about 5% of pregnancies and is responsible for approximately 16% of all maternal deaths globally. Pre-eclampsia also doubles

6399-399: The same target as for the general population. The issue of what is the best target and whether targets should differ for high risk individuals is unresolved, although some experts propose more intensive blood pressure lowering than advocated in some guidelines. For people who have never experienced cardiovascular disease who are at a 10-year risk of cardiovascular disease of less than 10%,

6480-501: The severity of toxicity. Some other complaints include fatigue, shortness of breath , kidney failure , and paralysis. The major dose-limiting toxicities of liquorice are corticosteroid in nature, because of the inhibitory effect that its chief active constituents, glycyrrhizin and enoxolone , have on cortisol degradation, and include edema , hypokalaemia , weight gain or loss, and hypertension . Hypertension Hypertension , also known as high blood pressure ,

6561-700: Was to be expected from the success of the product. After the war, Münster resumed production of the candies. In 1986 the confectionery company Haribo based in Bonn bought the production and rights to the Maoam candy. From 1930 to 1982 the candy was produced in a facility on Hildebrandtstraße of the Friedrichstadt district of Düsseldorf ; it now produced at the old Novesia  [ de ] factory on Jülicher Landstraße in Neuss . A popular slogan used in Maoam advertisements

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