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78-504: The Manalapan-Englishtown Regional School District is a regional public school district serving students in pre-kindergarten through eighth grade from the suburban communities of Englishtown and Manalapan Township in Monmouth County , in the U.S. state of New Jersey . As of the 2019–20 school year, the district, comprising eight schools, had an enrollment of 4,910 students and 408.4 classroom teachers (on an FTE basis), for

156-454: A school board ) may be elected, appointed by a political office holder, serve ex officio , or a combination of any of these. An independent school district is a legally separate body corporate and political . Most school districts operate as independent local governmental units with exclusive authority over K–12 public educational operations and policies. The extent of their control is set by state-level law. Litigation against school districts

234-494: A strain of coronavirus known as "severe acute respiratory syndrome coronavirus 2" ( SARS-CoV-2 ). COVID-19 is mainly transmitted when people breathe in air contaminated by droplets / aerosols and small airborne particles containing the virus. Infected people exhale those particles as they breathe, talk, cough, sneeze, or sing. Transmission is more likely the closer people are. However, infection can occur over longer distances, particularly indoors. The transmission of

312-564: A student–teacher ratio of 12.0:1. The district is classified by the New Jersey Department of Education as being in District Factor Group "GH", the third-highest of eight groupings. District Factor Groups organize districts statewide to allow comparison by common socioeconomic characteristics of the local districts. From lowest socioeconomic status to highest, the categories are A, B, CD, DE, FG, GH, I and J. Students from

390-481: A "board of trustees," "board of education," "school committee," etc.. This body usually appoints or hires an experienced public school administrator to function as the district's superintendent of schools – a district's chief executive . The superintendent oversees daily operations, decisions and implements the policies of the board. The school board may also exercise a quasi-judicial function in serious employee or student discipline matters. School districts in

468-419: A certain critical size, generally thought to be <100μm diameter, evaporate faster than they settle; due to that fact, they form respiratory aerosol particles that remain airborne for a long period of time over extensive distances. Infectivity can begin four to five days before the onset of symptoms. Infected people can spread the disease even if they are pre-symptomatic or asymptomatic . Most commonly,

546-603: A certain degree comparable to a school district. Other arrangements are possible: certain types of special schools in North Rhine-Westphalia are run by the Landschaftsverbände . There also exist private schools , mostly funded by the States, but run by private entities like churches or foundations. In Italy , school districts were established in 1974 by the " Provvedimenti Delegati sulla scuola " ("Assigned Laws [to

624-463: A consolidated to a regional district. The approval of the regionalization proposal meant that the district was eligible for increased state aid and would have property taxes allocated to the two municipalities based on the number of students enrolled from each community. Covering an area of 31 square miles (80 km), the district had 1,140 students in 1963. Population growth in the two constituent municipalities has led to enrollment growing to 3,200 by

702-561: A decline in property tax revenues during and after the Great Recession . By 2016 there were about 13,000 school districts, and the average student population was about 5,000. Although these terms can vary slightly between various states and regions, these are typical definitions for school district constitution: These terms may not appear in a district's name, even though the condition may apply. In England and Wales , school boards were established in 1870, and abolished in 1902, with

780-411: A decrease of 38,127 or 35%. Many states had passed laws facilitating school district consolidation. In 1951 the majority of the school districts in existence were rural school districts only providing elementary education, and some school districts did not operate schools but instead provided transportation to other schools. The Midwest had a large number of rural school districts. Previously areas of

858-418: A greater health concern than COVID. A group of such parents gathered during the board of education meeting in the evening of June 8, 2021, to protest, and persuaded the board of education to place Marciante on administrative leave through the end of the academic year, June 22. Immediately after, the board passed a motion to allow each individual parent to decide whether his or her child would attend school without

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936-422: A higher risk of developing severe symptoms. Some complications result in death. Some people continue to experience a range of effects ( long COVID ) for months or years after infection, and damage to organs has been observed. Multi-year studies are underway to further investigate the long-term effects of the disease. COVID‑19 transmission occurs when infectious particles are breathed in or come into contact with

1014-472: A mask against government policies. Core members of the district's administration are: The district's board of education , comprised of nine members, sets policy and oversees the fiscal and educational operation of the district through its administration. As a Type II school district, the board's trustees are elected directly by voters to serve three-year terms of office on a staggered basis, with three seats up for election each year held (since 2012) as part of

1092-632: A minority of secondary schools , a few primary schools, and much further education . (Most schools are neither organized geographically nor publicly managed, although the Department of Education inspects and funds them and pays teachers' salaries.) Each ETB area comprises one or more local authority areas , with city or county councilors forming the bulk of the ETB board. The ETBs was formed in 2005 by amalgamating Vocational Education Committees established in 1930, also based on local government areas. In Hong Kong ,

1170-423: A range of effects, such as fatigue , for prolonged periods after an initial COVID-19 infection. This is the result of a condition called long COVID , which can be described as a range of persistent symptoms that continue for months or years. Long-term damage to organs has been observed after the onset of COVID-19. Multi-year studies are underway to further investigate the protracted effects of long COVID. Reducing

1248-450: A school system that is separate but similar to a town's or a county's powers. These include the power to enter contacts, use eminent domain , and to issue binding rules and regulations affecting school policies and operations. The power of school districts to tax and spend is generally more limited. For example, many school districts in New York state require a majority of voters living in

1326-706: A single school district." Noting that most modern school districts were formed by consolidating one-room school districts in the first seven decades of the 20th century, Fischel argues that "outside the South, these consolidations were consented to by local voters" who "preferred districts whose boundaries conformed to their everyday interactions rather than formal units of government" and that "[t]he South ended up with county-based school districts because segregation imposed diseconomies of scale on district operations and required larger land-area districts." In New York , most school districts are separate governmental units with

1404-449: A state), most American school districts operate as independent local governmental units under a grant of authority and within geographic limits created by state law. The executive and legislative power over locally-controlled policies and operations of an independent school district are, in most cases, held by a school district's board of education. Depending on state law, members of a local board of education (often referred to informally as

1482-683: Is a contagious disease caused by the coronavirus SARS-CoV-2 . The first known case was identified in Wuhan , China, in December 2019. Most scientists believe the SARS-CoV-2 virus entered into human populations through natural zoonosis , similar to the SARS-CoV-1 and MERS-CoV outbreaks, and consistent with other pandemics in human history. Social and environmental factors including climate change , natural ecosystem destruction and wildlife trade increased

1560-686: Is a novel severe acute respiratory syndrome coronavirus. It was first isolated from three people with pneumonia connected to the cluster of acute respiratory illness cases in Wuhan. All structural features of the novel SARS-CoV-2 virus particle occur in related coronaviruses in nature, particularly in Rhinolophus sinicus (Chinese horseshoe bats). Outside the human body, the virus is destroyed by household soap which bursts its protective bubble . Hospital disinfectants, alcohols, heat, povidone-iodine , and ultraviolet -C (UV-C) irradiation are also effective disinfection methods for surfaces. SARS-CoV-2

1638-571: Is associated with COVID-19 and is reported in as many as 88% of symptomatic cases. Published data on the neuropathological changes related with COVID-19 have been limited and contentious, with neuropathological descriptions ranging from moderate to severe hemorrhagic and hypoxia phenotypes , thrombotic consequences, changes in acute disseminated encephalomyelitis (ADEM-type), encephalitis and meningitis . Many COVID-19 patients with co-morbidities have hypoxia and have been in intensive care for varying lengths of time, confounding interpretation of

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1716-433: Is available, guidelines and recommendations for hypertensive patients remain. The effect of the virus on ACE2 cell surfaces leads to leukocytic infiltration, increased blood vessel permeability, alveolar wall permeability, as well as decreased secretion of lung surfactants. These effects cause the majority of the respiratory symptoms. However, the aggravation of local inflammation causes a cytokine storm eventually leading to

1794-402: Is because pregnant women with COVID‑19 appear to be more likely to develop respiratory and obstetric complications that can lead to miscarriage , premature delivery and intrauterine growth restriction . Fungal infections such as aspergillosis , candidiasis , cryptococcosis and mucormycosis have been recorded in patients recovering from COVID‑19. COVID‑19 is caused by infection with

1872-522: Is closely related to the original SARS-CoV . It is thought to have an animal ( zoonotic ) origin. Genetic analysis has revealed that the coronavirus genetically clusters with the genus Betacoronavirus , in subgenus Sarbecovirus (lineage B) together with two bat-derived strains. It is 96% identical at the whole genome level to other bat coronavirus samples (BatCov RaTG13 ). The structural proteins of SARS-CoV-2 include membrane glycoprotein (M), envelope protein (E), nucleocapsid protein (N), and

1950-427: Is common and some law firms specialize in education law. Districts typically maintain professional liability insurance in order to pay its settlements and legal liabilities. As of 2023 in most U.S. states, public school districts may lay taxes to fund their operations. In others, such as Maine , some school districts are able to lay taxes and others are not. Independent school districts often exercise authority over

2028-595: Is the cause of the bud release and the formation of the viral envelope. The N and E protein are accessory proteins that interfere with the host's immune response. Human angiotensin converting enzyme 2 (hACE2) is the host factor that SARS-CoV-2 virus targets causing COVID‑19. Theoretically, the usage of angiotensin receptor blockers (ARB) and ACE inhibitors upregulating ACE2 expression might increase morbidity with COVID‑19, though animal data suggest some potential protective effect of ARB; however no clinical studies have proven susceptibility or outcomes. Until further data

2106-465: Is the viral component that attaches to the host receptor via the ACE2 receptors. It includes two subunits: S1 and S2. Studies have shown that S1 domain induced IgG and IgA antibody levels at a much higher capacity. It is the focus spike proteins expression that are involved in many effective COVID‑19 vaccines. The M protein is the viral protein responsible for the transmembrane transport of nutrients. It

2184-896: The Alpha variant (B.1.1.7, formerly called the UK variant), first found in London and Kent, the Beta variant (B.1.351, formerly called the South Africa variant), the Gamma variant (P.1, formerly called the Brazil variant), the Delta variant (B.1.617.2, formerly called the India variant), and the Omicron variant (B.1.1.529), which had spread to 57 countries as of 7 December. On December 19, 2023,

2262-665: The Education Bureau divides primary schools into 36 districts, known as school nets, for its Primary One Admission System . Of the 36 districts, districts 34 and 41 in Kowloon and districts 11 and 12 in Hong Kong Island are considered the most prestigious. In Iranian cities school kids normal registrations are limited by school districts, register is online at my.medu.ir and the parent sees schools within range online. COVID-19 Coronavirus disease 2019 ( COVID-19 )

2340-773: The Midwest and West tend to cross municipal boundaries, while school districts in New England and the Mid-Atlantic regions tend to adhere to city, township, and/or county boundaries. As of 1951 school districts were independent governmental units in 26 states, while in 17 states there were mixes of independent school districts and school districts subordinate to other local governments. In nine states there were only school districts subordinate to local governments. In most Southern states, school systems operate either as an arm of county government or at least share coextensive boundaries with

2418-572: The Spanish flu , Middle East respiratory syndrome , and Zika virus . In January 2020, the World Health Organization (WHO) recommended 2019-nCoV and 2019-nCoV acute respiratory disease as interim names for the virus and disease per 2015 guidance and international guidelines against using geographical locations or groups of people in disease and virus names to prevent social stigma . The official names COVID‑19 and SARS-CoV-2 were issued by

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2496-671: The Unorganized Borough of Alaska were not served by school districts but instead served by schools directly operated by the Alaska Department of Education and by Bureau of Indian Affairs (BIA) schools. The state schools were transferred to the Alaska State-Operated School System (SOS) after the Alaska Legislature created it in 1971; that agency was terminated in 1975, with its schools transferred to

2574-442: The county council and county borough councils becoming the local education authorities . In France, the system of the carte scolaire was dismantled by the beginning of the 2007 school year. More school choice has been given to French students; however, priority is given to those who meet the following criteria: In Germany , schools and teachers are predominately funded by the states of Germany , which also are in control of

2652-482: The small intestine . The virus can cause acute myocardial injury and chronic damage to the cardiovascular system . An acute cardiac injury was found in 12% of infected people admitted to the hospital in Wuhan, China, and is more frequent in severe disease. Rates of cardiovascular symptoms are high, owing to the systemic inflammatory response and immune system disorders during disease progression, but acute myocardial injuries may also be related to ACE2 receptors in

2730-705: The spike protein (S). The M protein of SARS-CoV-2 is about 98% similar to the M protein of bat SARS-CoV, maintains around 98% homology with pangolin SARS-CoV, and has 90% homology with the M protein of SARS-CoV; whereas, the similarity is only around 38% with the M protein of MERS-CoV . The many thousands of SARS-CoV-2 variants are grouped into either clades or lineages . The WHO, in collaboration with partners, expert networks, national authorities, institutions and researchers, have established nomenclature systems for naming and tracking SARS-CoV-2 genetic lineages by GISAID , Nextstrain and Pango . The expert group convened by

2808-409: The 2019–20 school year, the high school had an enrollment of 1,879 students and 122.8 classroom teachers (on an FTE basis), for a student–teacher ratio of 15.3:1 and Freehold Township High School had an enrollment of 2,029 students and 133.2 classroom teachers (on an FTE basis), for a student–teacher ratio of 15.2:1. In June 1963, voters approved a referendum by a more than 10-1 margin changing from

2886-538: The B.1 lineage. Several notable variants of SARS-CoV-2 emerged throughout 2020. Cluster 5 emerged among minks and mink farmers in Denmark . After strict quarantines and the slaughter of all the country's mink , the cluster was assessed to no longer be circulating among humans in Denmark as of 1 February 2021. As of December 2021 , there are five dominant variants of SARS-CoV-2 spreading among global populations:

2964-539: The CNS, possibly within an infected white blood cell. Research conducted when Alpha was the dominant variant has suggested COVID-19 may cause brain damage. Later research showed that all variants studied (including Omicron) killed brain cells, but the exact cells killed varied by variant. It is unknown if such damage is temporary or permanent. Observed individuals infected with COVID-19 (most with mild cases) experienced an additional 0.2% to 2% of brain tissue lost in regions of

3042-557: The COVID-19 infection may have different symptoms, and their symptoms may change over time. Three common clusters of symptoms have been identified: a respiratory symptom cluster with cough, sputum , shortness of breath , and fever; a musculoskeletal symptom cluster with muscle and joint pain, headache, and fatigue; and a cluster of digestive symptoms with abdominal pain, vomiting, and diarrhea. In people without prior ear, nose, or throat disorders, loss of taste combined with loss of smell

3120-546: The Government] about the school"). Each district must contain a minimum of 10,000 inhabitants. The national government attempted to link the local schools with local society and culture and local governments. The school districts were dissolved in 2003 by the "legge finanziaria" (law about the government budget) in an attempt to trim the national budget. In the Republic of Ireland, 16 Education and Training Boards (ETBs) administer

3198-725: The November general election. The board appoints a superintendent to oversee the district's day-to-day operations and a business administrator to supervise the business functions of the district. Seats on the nine-member board are allocated based on population, with eights seats assigned to Manalapan Township and one to Englishtown. School district In the U.S., most K–12 public schools function as units of local school districts. A school district usually operate several elementary , middle , and high schools . The largest urban and suburban districts operate hundreds of schools. While practice varies significantly by state (and in some cases, within

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3276-459: The United States tend to be different from the demographics of the students. This difference is "most pronounced in majority nonwhite jurisdictions and school districts with the largest racial achievement gaps ." There were 130,000 school districts in the country in 1930, with an average student population of 150. From 1942 to 1951 the number of school districts declined from 108,579 to 70,452,

3354-472: The WHO declared that another distinctive variant, JN.1, had emerged as a "variant of interest". Though the WHO expected an increase in cases globally, particularly for countries entering winter, the overall global health risk was considered low. The SARS-CoV-2 virus can infect a wide range of cells and systems of the body. COVID‑19 is most known for affecting the upper respiratory tract (sinuses, nose, and throat) and

3432-759: The WHO on 11 February 2020 with COVID-19 being shorthand for "coronavirus disease 2019". The WHO additionally uses "the COVID‑19 virus" and "the virus responsible for COVID‑19" in public communications. The symptoms of COVID-19 are variable depending on the type of variant contracted, ranging from mild symptoms to a potentially fatal illness. Common symptoms include coughing , fever , loss of smell (anosmia) and taste (ageusia), with less common ones including headaches , nasal congestion and runny nose , muscle pain , sore throat , diarrhea , eye irritation , and toes swelling or turning purple, and in moderate to severe cases, breathing difficulties . People with

3510-547: The WHO recommended the labelling of variants using letters of the Greek alphabet , for example, Alpha , Beta , Delta , and Gamma , giving the justification that they "will be easier and more practical to discussed by non-scientific audiences". Nextstrain divides the variants into five clades (19A, 19B, 20A, 20B, and 20C), while GISAID divides them into seven (L, O, V, S, G, GH, and GR). The Pango tool groups variants into lineages , with many circulating lineages being classed under

3588-515: The brain connected to the sense of smell compared with uninfected individuals, and the overall effect on the brain was equivalent on average to at least one extra year of normal ageing; infected individuals also scored lower on several cognitive tests. All effects were more pronounced among older ages. The virus also affects gastrointestinal organs as ACE2 is abundantly expressed in the glandular cells of gastric , duodenal and rectal epithelium as well as endothelial cells and enterocytes of

3666-591: The brain found as complications leading to death in people infected with COVID‑19. Infection may initiate a chain of vasoconstrictive responses within the body, including pulmonary vasoconstriction – a possible mechanism in which oxygenation decreases during pneumonia. Furthermore, damage of arterioles and capillaries was found in brain tissue samples of people who died from COVID‑19. COVID‑19 may also cause substantial structural changes to blood cells , sometimes persisting for months after hospital discharge. A low level of blood lymphocytess may result from

3744-428: The brains of those who have died from COVID‑19, but these results need to be confirmed. While virus has been detected in cerebrospinal fluid of autopsies, the exact mechanism by which it invades the CNS remains unclear and may first involve invasion of peripheral nerves given the low levels of ACE2 in the brain. The virus may also enter the bloodstream from the lungs and cross the blood–brain barrier to gain access to

3822-409: The clear jelly liquid found in lung autopsies of people who died of COVID-19. One possibility addressed in medical research is that hyuralonic acid (HA) could be the leading factor for this observation of the clear jelly liquid found in the lungs, in what could be hyuralonic storm, in conjunction with cytokine storm . One common symptom, loss of smell, results from infection of the support cells of

3900-406: The data. Of people who show symptoms, 81% develop only mild to moderate symptoms (up to mild pneumonia ), while 14% develop severe symptoms ( dyspnea , hypoxia , or more than 50% lung involvement on imaging) that require hospitalization, and 5% of patients develop critical symptoms ( respiratory failure , septic shock , or multiorgan dysfunction ) requiring ICU admission. At least a third of

3978-464: The district or the local government to approval their annual budget, but school districts in Virginia have no taxing authority and must depend on another local government (county, city, or town) for funding. A district's governing body, usually called a school board , is typically elected by direct popular vote but may be appointed by other governmental officials. The governing body might also be known as

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4056-604: The early 1980s to more than 5,000 in 2017. The student body is primarily from Manalapan Township, which accounts for about 95% of enrollment, with Englishtown students accounting for the remaining 5%. After the 1960 United States census , Manalapan Township accounted for 78% of the district's overall population, with 22% from Englishtown. The population in Englishtown increased from 1,143 in 1960 to 1,847 in 2010, an increase of more than 60%, while Manalapan Township grew almost tenfold, from 3,990 to 38,872, over that same period, so that

4134-405: The elementary and intermediate schools as the district's middle school building was not yet ready for use. Inspections had identified between 100 and 300 code violations, and the school could not be granted a certificate of occupancy . While the building was being completed, students attended school on the school's four-hour day schedule in cafeterias, gymnasiums, auditoriums, and empty classrooms in

4212-685: The elementary and intermediate schools. As of September 25, 2006, students resumed a full day schedule at the Manalapan-Englishtown Middle School. During the COVID-19 pandemic, the district superintendent John Marciante abided by the New Jersey state government's policies in regards to the wearing of face masks in order to protect the wider community against the spread of the virus. On June 8, 2021, amidst rising summer temperatures, some parents became concerned that wearing masks would become

4290-716: The expression of ACE-2, thereby facilitating the SARS-Cov2 virus to enter cells and to replicate. A competition of negative feedback loops (via protective effects of interferon alpha) and positive feedback loops (via upregulation of ACE-2) is assumed to determine the fate of patients suffering from COVID-19. Additionally, people with COVID‑19 and acute respiratory distress syndrome (ARDS) have classical serum biomarkers of CRS, including elevated C-reactive protein (CRP), lactate dehydrogenase (LDH), D-dimer , and ferritin . Systemic inflammation results in vasodilation , allowing inflammatory lymphocytic and monocytic infiltration of

4368-428: The eyes, nose, or mouth. The risk is highest when people are in close proximity, but small airborne particles containing the virus can remain suspended in the air and travel over longer distances, particularly indoors. Transmission can also occur when people touch their eyes, nose or mouth after touching surfaces or objects that have been contaminated by the virus. People remain contagious for up to 20 days and can spread

4446-521: The face. While drugs have been developed to inhibit the virus, the primary treatment is still symptomatic , managing the disease through supportive care , isolation , and experimental measures . During the initial outbreak in Wuhan , the virus and disease were commonly referred to as "coronavirus" and "Wuhan coronavirus", with the disease sometimes called "Wuhan pneumonia". In the past, many diseases have been named after geographical locations, such as

4524-523: The heart. ACE2 receptors are highly expressed in the heart and are involved in heart function. A high incidence of thrombosis and venous thromboembolism occurs in people transferred to intensive care units with COVID‑19 infections, and may be related to poor prognosis. Blood vessel dysfunction and clot formation (as suggested by high D-dimer levels caused by blood clots) may have a significant role in mortality, incidents of clots leading to pulmonary embolisms , and ischaemic events (strokes) within

4602-500: The host cell. Following viral entry, COVID‑19 infects the ciliated epithelium of the nasopharynx and upper airways. Autopsies of people who died of COVID‑19 have found diffuse alveolar damage , and lymphocyte-containing inflammatory infiltrates within the lung. From the CT scans of COVID-19 infected lungs, white patches were observed containing fluid known as ground-glass opacity (GGO) or simply ground glass. This tended to correlate with

4680-522: The infection, children may develop paediatric multisystem inflammatory syndrome , which has symptoms similar to Kawasaki disease , which can be fatal. In very rare cases, acute encephalopathy can occur, and it can be considered in those who have been diagnosed with COVID‑19 and have an altered mental status. According to the US Centers for Disease Control and Prevention , pregnant women are at increased risk of becoming seriously ill from COVID‑19. This

4758-800: The likelihood of such zoonotic spillover . The disease quickly spread worldwide, resulting in the COVID-19 pandemic . The symptoms of COVID‑19 are variable but often include fever, fatigue, cough, breathing difficulties , loss of smell , and loss of taste . Symptoms may begin one to fourteen days after exposure to the virus. At least a third of people who are infected do not develop noticeable symptoms . Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia ), while 14% develop severe symptoms ( dyspnea , hypoxia , or more than 50% lung involvement on imaging), and 5% develop critical symptoms ( respiratory failure , shock , or multiorgan dysfunction ). Older people are at

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4836-450: The lower respiratory tract (windpipe and lungs). The lungs are the organs most affected by COVID‑19 because the virus accesses host cells via the receptor for the enzyme angiotensin-converting enzyme 2 (ACE2), which is most abundant on the surface of type II alveolar cells of the lungs. The virus uses a special surface glycoprotein called a " spike " to connect to the ACE2 receptor and enter

4914-409: The lung and the heart. In particular, pathogenic GM-CSF-secreting T cells were shown to correlate with the recruitment of inflammatory IL-6-secreting monocytes and severe lung pathology in people with COVID‑19. Lymphocytic infiltrates have also been reported at autopsy. Multiple viral and host factors affect the pathogenesis of the virus. The S-protein , otherwise known as the spike protein,

4992-447: The moment a person first becomes infected and the appearance of the first symptoms. The median delay for COVID-19 is four to five days possibly being infectious on 1–4 of those days. Most symptomatic people experience symptoms within two to seven days after exposure, and almost all will experience at least one symptom within 12 days. Most people recover from the acute phase of the disease. However, some people continue to experience

5070-585: The newly created Alaska Unorganized Borough School District, which was broken apart into twenty-one school districts the following year. In the 2022 Census of Governments, the United States Census Bureau enumerated the following numbers of school systems in the United States: School districts in the US have reduced the number of their employees by 3.3%, or 270,000 between 2008 and 2012, owing to

5148-480: The olfactory epithelium , with subsequent damage to the olfactory neurons . The involvement of both the central and peripheral nervous system in COVID‑19 has been reported in many medical publications. It is clear that many people with COVID-19 exhibit neurological or mental health issues . The virus is not detected in the central nervous system (CNS) of the majority of COVID-19 patients with neurological issues . However, SARS-CoV-2 has been detected at low levels in

5226-504: The overall education policies. On the other hand, school buildings are mostly run and funded by municipal governments on different levels of the municipal system (municipalities proper, districts), depending on the size and specialization of a certain school or the population size of a certain municipality. As with other fields of government, for more specialized schools, special government bodies ("Zweckverband") can be established, where municipalities, and not voters, are members; these are to

5304-488: The peak viral load in upper respiratory tract samples occurs close to the time of symptom onset and declines after the first week after symptoms begin. Current evidence suggests a duration of viral shedding and the period of infectiousness of up to ten days following symptom onset for people with mild to moderate COVID-19, and up to 20 days for persons with severe COVID-19, including immunocompromised people. Severe acute respiratory syndrome coronavirus   2 (SARS-CoV-2)

5382-411: The people who are infected with the virus do not develop noticeable symptoms at any point in time. These asymptomatic carriers tend not to get tested and can still spread the disease. Other infected people will develop symptoms later (called "pre-symptomatic") or have very mild symptoms and can also spread the virus. As is common with infections, there is a delay, or incubation period , between

5460-608: The population ratio between Manalapan Township and Englishtown is nearly 20:1. Clarks Mills School was one of nine schools in New Jersey honored in 2020 by the National Blue Ribbon Schools Program , which recognizes high student achievement. Schools in the district (with 2019–20 enrollment from the National Center for Education Statistics ) are: Starting September 12, 2006, the approximately 1,400 students of Manalapan-Englishtown Middle School had to learn in

5538-441: The power to levy taxes and incur debt, except for the five cities with a population of over 125,000 ( Buffalo , Rochester , Syracuse , Yonkers , and New York City ), where the schools are operated directly by the municipalities. The Hawaii State Department of Education functions as a single statewide school district, unique among states. According to a 2021 study, the demographics of voters who elect local school boards in

5616-416: The respiratory tract, people with severe COVID‑19 have symptoms of systemic hyperinflammation. Clinical laboratory findings of elevated IL‑2 , IL‑6 , IL‑7 , as well as the following suggest an underlying immunopathology: Interferon alpha plays a complex, Janus-faced role in the pathogenesis of COVID-19. Although it promotes the elimination of virus-infected cells, it also upregulates

5694-859: The risk of long COVID includes staying up to date on the most recent COVID-19 vaccine, practicing good hygiene, maintaining clean indoor air, and physical distancing from people infected with a respiratory virus. Complications may include pneumonia , acute respiratory distress syndrome (ARDS), multi-organ failure , septic shock , and death. Cardiovascular complications may include heart failure, arrhythmias (including atrial fibrillation ), heart inflammation , thrombosis , particularly venous thromboembolism , and endothelial cell injury and dysfunction. Approximately 20–30% of people who present with COVID‑19 have elevated liver enzymes , reflecting liver injury. Neurologic manifestations include seizure , stroke, encephalitis , and Guillain–Barré syndrome (which includes loss of motor functions ). Following

5772-551: The state's counties. A 2010 study by economist William A. Fischel found that "two-thirds of medium-to-large American cities have boundaries that substantially overlap those of a single school district" with substantial regional and state variations in the degree of overlap, "ranging from nearly perfect congruence in New England , New Jersey, and Virginia, to hardly any in Illinois, Texas, and Florida." Older and more populous municipalities "tend to have boundaries that closely match those of

5850-577: The two communities in public school for ninth through twelfth grades attend either Manalapan High School (all students from Englishtown and some from Manalapan) or Freehold Township High School (which serves other Manalapan students), as part of the Freehold Regional High School District . The Freehold Regional High School District also serves students from Colts Neck Township , Farmingdale , Freehold Borough , Freehold Township , Howell Township and Marlboro Township . As of

5928-507: The virus acting through ACE2-related entry into lymphocytes. Another common cause of death is complications related to the kidneys . Early reports show that up to 30% of hospitalised patients both in China and in New York have experienced some injury to their kidneys, including some persons with no previous kidney problems. Although SARS-CoV-2 has a tropism for ACE2-expressing epithelial cells of

6006-752: The virus even if they do not develop symptoms. Testing methods for COVID-19 to detect the virus's nucleic acid include real-time reverse transcription polymerase chain reaction (RT‑PCR), transcription-mediated amplification , and reverse transcription loop-mediated isothermal amplification (RT‑LAMP) from a nasopharyngeal swab . Several COVID-19 vaccines have been approved and distributed in various countries, many of which have initiated mass vaccination campaigns . Other preventive measures include physical or social distancing , quarantining , ventilation of indoor spaces, use of face masks or coverings in public, covering coughs and sneezes, hand washing , and keeping unwashed hands away from

6084-509: The virus is carried out through virus-laden fluid particles, or droplets, which are created in the respiratory tract, and they are expelled by the mouth and the nose. There are three types of transmission: "droplet" and "contact", which are associated with large droplets, and "airborne", which is associated with small droplets. If the droplets are above a certain critical size, they settle faster than they evaporate , and therefore they contaminate surfaces surrounding them. Droplets that are below

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