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Marcello Malpighi

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116-454: Marcello Malpighi (10 March 1628 – 30 November 1694) was an Italian biologist and physician , who is referred to as the "Founder of microscopical anatomy, histology & Father of physiology and embryology". Malpighi's name is borne by several physiological features related to the biological excretory system , such as the Malpighian corpuscles and Malpighian pyramids of the kidneys and

232-448: A regional or minority language native to Italy, the existence of which predates the national language. Although there is disagreement on the total number, according to UNESCO , there are approximately 30 languages native to Italy , although many are often misleadingly referred to as "Italian dialects ". Since 2017, in addition to the approximately 55 million Italians in Italy (91% of

348-694: A worldwide famous cuisine . Due to comparatively late national unification, and the historical autonomy of the regions that comprise the Italian peninsula, many traditions and customs of the Italians can be identified by their regions of origin. Despite the political and social isolation of these regions, Italy's contributions to the cultural and historical heritage of the Western world remain immense. Famous elements of Italian culture are its opera and music, its iconic gastronomy and food, which are commonly regarded as amongst

464-566: A Napoleonic sister republic of Revolutionary France , took place, on the basis of the events following the French Revolution (1789–1799) which, among its ideals, advocated the national self-determination . This event is celebrated by the Tricolour Day . The Italian national colours appeared for the first time on a tricolour cockade in 1789, anticipating by seven years the first green, white and red Italian military war flag , which

580-475: A bovine tongue Malpighi dividing the tongue papillae into separate "patches" on the tongues length. When studying the brain, he was one of the first to try to map the grey and white tissue and hypothesized a connection between the brain and spinal cord through nerve endings. Malpighi's work on plant anatomy was inspired in Messina when visiting his patron Visconte Ruffo's garden where a chestnut tree's split branch had

696-414: A closed system of circulation in animals. Furthering his analysis of the lungs, Malpighi identified the airways branched into thin membraned spherical cavities which he likened to honeycomb holes surrounded by capillary vessels, in his 1661 work "De pulmonibus observationes anatomicae". These lung structures now known as alveoli he used to describe the air pathway as continuous inhalation and exhalation with

812-459: A defeat on the forces of Pope Urban VIII in 1643. The treasury was so empty that when the Castro mercenaries were paid for the state could no longer afford to pay interest on government bonds. The interest rate was lowered by 0.75%. The economy became so decrepit that barter trade became prevalent in rural market places. Ferdinando died on 23 May 1670 of apoplexy and dropsy . He was interred in

928-434: A family of tropical and subtropical flowering plants. Because Malpighi was concerned with teratology (the scientific study of the visible conditions caused by the interruption or alteration of normal development) he expressed grave misgivings about the view of his contemporaries that the galls of trees and herbs gave birth to insects. He conjectured (correctly) that the creatures in question arose from eggs previously laid in

1044-619: A full-fledged hearing and kept Galileo in Florence until December 1632, when the Roman Inquisitors finally threatened to bring Galileo to Rome in chains if he would not come voluntarily. In June 1633, the Roman Inquisition convicted the astronomer for "vehement suspicion of heresy" and sentenced him to imprisonment for life. After this was commuted to house arrest, Ferdinando came to visit the elderly scientist at his villa, where he lived out

1160-675: A key role in ushering the Age of Discovery and the European colonization of the Americas. The most notable among them were: Christopher Columbus (Italian: Cristoforo Colombo [kriˈstɔːforo koˈlombo] ), colonist in the name of Spain, who is credited with discovering the New World and the opening of the Americas for conquest and settlement by Europeans; John Cabot (Italian: Giovanni Caboto [dʒoˈvanni kaˈbɔːto] ), sailing for England, who

1276-571: A lesser extent in the Middle East ( Italians in the United Arab Emirates ). Italians have influenced and contributed to fields like arts and music , science , technology , fashion , cinema , cuisine , restaurants , sports , jurisprudence , banking and business . Furthermore, Italian people are generally known for their attachment to their locale, expressed in the form of either regionalism or municipalism . Hypotheses for

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1392-554: A marble monument to the scientist with an inscription in Latin remembering – among other things – his "SUMMUM INGENIUM / INTEGERRIMAM VITAM / FORTEM STRENUAMQUE MENTEM / AUDACEM SALUTARIS ARTIS AMOREM" (great genius, honest life, strong and tough mind, daring love for the medical art). Around the age of 38, and with a remarkable academic career behind him, Malpighi decided to dedicate his free time to anatomical studies. Although he conducted some of his studies using vivisection and others through

1508-615: A marriage with Vittoria della Rovere , a granddaughter of the last Duke of Urbino , in 1633, in hopes of acquiring the Duchy. However, their political weakness prevented them from securing Urbino, and it was subsequently conquered by the Papal States . In his seventeenth year, Ferdinando embarked on a tour of Europe, traveling to Rome , Bologna , Ferrara , Venice , and finally Austria and Prague . One year later, his regency ended and his personal rule began. The dowager Grand Duchess Christina

1624-519: A medical doctor at the age of 25. Subsequently, he was appointed as a teacher, whereupon he immediately dedicated himself to further study in anatomy and medicine. For most of his career, Malpighi combined an intense interest in scientific research with a fond love of teaching. He was invited to correspond with the Royal Society in 1667 by Henry Oldenburg , and became a fellow of the society the next year. In 1656, Ferdinand II of Tuscany invited him to

1740-441: A microscope, after Jan Swammerdam . His treatise De polypo cordis (1666) was important for understanding blood composition, as well as how blood clots. In it, Malpighi described how the form of a blood clot differed in the right against the left sides of the heart . The use of the microscope enabled Malpighi to discover that insects do not use lungs to breathe, but small holes in their skin called tracheae. Malpighi also studied

1856-781: A result of invasions by another Germanic tribe, the Lombards . Much of the peninsula was now politically dominated by the Kingdom of the Lombards ; however, remnants of Byzantine control remained, especially in Southern Italy , where the Byzantine Empire retained control into the 11th century until the Norman conquest of Southern Italy . In addition to the Normans , Arabs conquered parts of Southern Italy in

1972-591: A result, Malpighi was made a member of the Royal Society in 1669. In 1671, Malpighi's Anatomy of Plants was published in London by the Royal Society, and he simultaneously wrote to Mr. Oldenburg, telling him of his recent discoveries regarding the lungs , fibres of the spleen and testicles , and several other discoveries involving the brain and sensory organs . He also shared more information regarding his research on plants. At that time, he related his disputes with some younger physicians who were strenuous supporters of

2088-470: A ring-like portion of bark was removed on a trunk a swelling occurred in the tissues above the ring, and he correctly interpreted this as growth stimulated by food coming down from the leaves, and being blocked above the ring. Malpighi was born on 10 March 1628 at Crevalcore near Bologna , Italy . The son of well-to-do parents, Malpighi was educated in his native city, entering the University of Bologna at

2204-489: A structure that intrigued him, this structure in modern literature being xylem . He examined the structure in different plants and noted the arrangement of xylem was in either a ring shape or in scattered groupings in the stem. This distinction was later used by biologists to separate the two major families of plants. A talented sketch artist, Malpighi seems to have been the first author to have made detailed drawings of individual organs of flowers. In his Anatome plantarum

2320-462: A supplementary volume in 1697. In his autobiography, Malpighi speaks of his Anatome Plantarum , decorated with the engravings of Robert White , as "the most elegant format in the whole literate world." His study of plants led him to conclude that plants had tubules similar to those he saw in insects like the silkworm (using his microscope, he probably saw the stomata, through which plants exchange carbon dioxide with oxygen). Malpighi observed that when

2436-454: A volume containing a series of exquisitely drawn and engraved images of the stages of development of Leguminosae (beans) and Cucurbitaceae (squash, melons). Later, he published material depicting the development of the date palm. The great Swedish botanist Linnaeus named the genus Malpighia in honour of Malpighi's work with plants; Malpighia is the type genus for the Malpighiaceae ,

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2552-733: Is Marco Polo , explorer of the 13th century, who recorded his 24 years-long travels in the Book of the Marvels of the World , introducing Europeans to Central Asia and China. The country boasts several world-famous cities. Rome was the ancient capital of the Roman Empire, seat of the Pope of the Catholic Church, capital of reunified Italy and artistic, cultural and cinematographic centre of world relevance. Florence

2668-494: Is a longitudinal section of a flower of Nigella (his Melanthi, literally honey-flower) with details of the nectariferous organs. He adds that it is strange that nature has produced on the leaves of the flower shell-like organs in which honey is produced. Malpighi had success in tracing the ontogeny of plant organs, and the serial development of the shoot owing to his instinct shaped in the sphere of animal embryology. He specialized in seedling development, and in 1679, he published

2784-538: Is considered the "father of the Italian flag". After the Battle of Waterloo , the reaction set in with the Congress of Vienna allowed the restoration of many of the old rulers and systems under Austrian domination. The concept of nationalism continued strong, however, and sporadic outbreaks led by such inveterate reformers as Giuseppe Mazzini occurred in several parts of the peninsula down to 1848–49. In this context, in 1847,

2900-568: The Baroque , Neoclassicism , the Risorgimento , Fascism , and European integration . Italy also became a seat of great formal learning in 1088 with the establishment of the University of Bologna , the oldest university in continuous operation , and the first university in the sense of a higher-learning and degree-awarding institute, as the word universitas was coined at its foundation. Many other Italian universities soon followed. For example,

3016-633: The Basilica of San Lorenzo , the Medicis' crypt. Ferdinando was obsessed with new technology and had several hygrometers , barometers , thermometers and telescopes installed in the Palazzo Pitti . In 1654, influenced by Galileo Galilei , he is reported to have invented the sealed-glass thermometer by sealing the glass tip of a tube filled to a certain height with colored alcohol. Small glass bubbles filled with air at varying pressures hovered trapped within

3132-843: The Italian geographical region . Italians share a common culture , history , ancestry and language . Their predecessors differ regionally, but generally include native populations such as the Etruscans , the Rhaetians , the Ligurians , the Adriatic Veneti , and the Italic peoples , including the Latins , from which the Romans emerged and helped create and evolve the modern Italian identity. Foreign influences include

3248-470: The Kingdom of Sicily . From the 11th century on, Italian cities began to grow rapidly in independence and importance. They became centres of political life, banking , and foreign trade. Some became wealthy, and many, including Florence , Rome , Genoa , Milan , Pisa , Siena and Venice , grew into nearly independent city-states and maritime republics . Each had its own foreign policy and political life. They all resisted, with varying degrees of success,

3364-438: The Malpighian tubule system of insects . The splenic lymphoid nodules are often called the "Malpighian bodies of the spleen" or Malpighian corpuscles . The botanical family Malpighiaceae is also named after him. He was the first person to see capillaries in animals, and he discovered the link between arteries and veins that had eluded William Harvey . Malpighi was one of the earliest people to observe red blood cells under

3480-447: The Nation through emblems , metaphors , personifications , allegories , which are shared by the entire Italian people. Some of them are official, i.e. they are recognized by the Italian state authorities, while others are part of the identity of the country without being defined by law. Traditions of Italy are sets of traditions , beliefs , values , and customs that belongs within

3596-673: The Ostrogoths . Theodoric and Odoacer ruled jointly until 493, when Theodoric murdered Odoacer. Theodoric continued to rule Italy with an army of Ostrogoths and a government that was mostly Italian. After the death of Theodoric in 526, the kingdom began to grow weak. By 553, emperor Justinian I expelled the Ostrogoths, and Italy was included into the Byzantine Empire under the Justinian dynasty . Byzantine rule in much of Italy collapsed by 572 as

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3712-464: The Papal States in central Italy. The Lombards remained a threat to papal power, however, until they were crushed by Charlemagne in 774. Charlemagne added the Kingdom of the Lombards to his vast realm. In recognition of Charlemagne's power, and to cement the church's alliance with him, Charlemagne was crowned emperor of the Romans by Pope Leo III in 800. After Charlemagne's death in 814, his son Louis

3828-526: The Peripatetics and Galenists (those who followed the precepts of Galen and were spearheaded at the University Bologna by fellow physician but inveterate foe Giovanni Girolamo Sbaraglia ), which were destroyed when his house burned down. Weary of philosophical disputation, in 1660, Malpighi returned to Bologna and dedicated himself to the study of anatomy. He subsequently discovered a new structure of

3944-573: The Praetorian prefecture of Italy ( praefectura praetoria Italiae ), and was subdivided into two dioceses. Diocesis Italia annonaria (Italy of the annona , governed from Milan) and Diocesis Italia Suburbicaria (Italy "under the government of the urbs ", i.e. governed from Rome). Christianity became the Roman state religion in AD 380, under Emperor Theodosius I . The last Western emperor, Romulus Augustulus ,

4060-635: The Schola Medica Salernitana , in southern Italy, was the first medical school in Europe. These great centres of learning presaged the Rinascimento : the European Renaissance began in Italy and was fueled throughout Europe by Italian painters, sculptors, architects, scientists, literature masters and music composers. Italy continued its leading cultural role through the Baroque period and into

4176-554: The Uffizi Gallery . The Catholic Church openly condemned the Mafia, and two churches were bombed and an anti-Mafia priest shot dead in Rome. Giovanni Falcone and Paolo Borsellino were named as heroes of the last 60 years in 13 November 2006 issue of Time . Italy is considered one of the birthplaces of Western civilization and a cultural superpower . Italian culture is the culture of

4292-472: The University of Bologna while he was very young. He joined the school of anatomy under Bartolomeo Massari and was one of nine students who met at the home of the master to conduct dissections. He married Francesca the daughter of Massari but it was short-lived as she died shortly after. Despite opposition from the university authorities because he was non-Bolognese by birth, in 1653 he was granted doctorates in both medicine and philosophy. He later graduated as

4408-840: The culture of Italian people. These traditions have influenced life in Italy for centuries, and are still practiced in modern times. Italian traditions are directly connected to Italy's ancestors, which says even more about Italian history . Folklore of Italy refers to the folklore and urban legends of Italy . Within the Italian territory, various peoples have followed one another over time, each of which has left its mark on current culture. Some tales also come from Christianization , especially those concerning demons , which are sometimes recognized by Christian demonology . Italian folklore also includes Italian folk dance , Italian folk music and folk heroes . Ferdinand II of Tuscany Ferdinando II de' Medici (14 July 1610 – 23 May 1670)

4524-689: The four great powers after the victory of the Allies . In the decades following unification, Italy began creating colonies in Africa , and under Benito Mussolini 's fascist regime conquered Ethiopia , founding the Italian Empire in 1936. The population of Italy grew to 45 million in 1940 and the economy, which had been based upon agriculture until that time, started its industrial development, mainly in northern Italy. World War II soon severely damaged Italy and destroyed its colonial power. Between 1945 and 1948,

4640-796: The " Maxi Trial ", and of the new anti-mafia measures launched by the government. In 1992, two major dynamite attacks killed the judges Giovanni Falcone (23 May in the Capaci bombing ) and Paolo Borsellino (19 July in the Via D'Amelio bombing ). One year later (May–July 1993), tourist spots were attacked, such as the Via dei Georgofili in Florence, Via Palestro in Milan, and the Piazza San Giovanni in Laterano and Via San Teodoro in Rome, leaving 10 dead and 93 injured and causing severe damage to cultural heritage such as

4756-527: The 14th century, and led to an unparalleled flourishing of the arts, literature, music, and science. However, the city-states were often troubled by violent disagreements among their citizens. The most famous division was between the Guelphs and Ghibellines . The Guelphs supported supreme rule by the pope, and the Ghibellines favoured the emperor. City-states often took sides and waged war against each other. During

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4872-532: The 9th century, establishing an Emirate of Sicily that lasted until it was also eventually overtaken by the Normans in the 11th century. The subsequent interaction between Latin, Byzantine, Arab, and Norman cultures resulted in the formation of a Norman-Arab-Byzantine culture in Southern Italy. During the 5th and 6th centuries, the popes increased their influence in both religious and political matters in Italy. It

4988-764: The Elder 's Origines , the first work of history composed in Latin , described Italy as the entire peninsula south of the Alps . According to Cato and several Roman authors, the Alps formed the "walls of Italy". In 264 BC, Roman Italy extended from the Arno and Rubicon rivers of the centre-north to the entire south. The northern area of Cisalpine Gaul was occupied by Rome in the 220s BC and became considered geographically and de facto part of Italy, but remained politically and de jure separated. It

5104-625: The European kings who opposed France. After the French king was overthrown and France became a republic, secret clubs favouring an Italian republic were formed throughout Italy. The armies of the French Republic began to move across Europe. In 1796, Napoleon Bonaparte led a French army into northern Italy and drove out the Austrian rulers. Once again, Italy was the scene of battle between the Habsburgs and

5220-517: The French. Wherever France conquered, Italian republics were set up, with constitutions and legal reforms. Napoleon made himself emperor in 1804, and part of northern and central Italy was unified under the name of the Kingdom of Italy, with Napoleon as king. The rest of northern and central Italy was annexed by France. Only Sicily, where the Bourbon king had taken refuge upon the French invasion of Naples, and

5336-564: The Galenic principles and opposed all new discoveries. Following many other discoveries and publications, in 1691, Malpighi was invited to Rome by Pope Innocent XII to become a papal physician and professor of medicine at the Papal Medical School. He remained in Rome until his death. Marcello Malpighi is buried in the church of Santi Gregorio e Siro , in Bologna , where nowadays can be seen

5452-602: The Italian economy which, until the late 1960s, enjoyed a period of sustained economic growth commonly called the " Economic Miracle ". In 1957, Italy was a founding member of the European Economic Community (EEC), which became the European Union (EU) in 1993. Italy faced several terror attacks between 1992 and 1993 perpetrated by the Sicilian Mafia as a consequence of several life sentences pronounced during

5568-504: The Italian national population), Italian-speaking autonomous groups are found in neighboring nations; about a half million are in Switzerland , as well as in France , the entire population of San Marino . In addition, there are also clusters of Italian speakers in the former Yugoslavia , primarily in Istria , located between in modern Croatia and Slovenia (see: Istrian Italians ), and Dalmatia , located in present-day Croatia and Montenegro (see: Dalmatian Italians ). Due to

5684-452: The Italian peninsula without Italian citizenship. The Latin equivalent of the term Italian had been in use for natives of the geographical region since antiquity. The majority of Italian nationals are native speakers of the country's official language, Italian, a Romance language of the Indo-European language family that evolved from the Vulgar Latin , or a variety thereof, that is regional Italian . However, many of them also speak

5800-423: The Italians and is incredibly diverse spanning the entirety of the Italian peninsula and the islands of Sardinia and Sicily . Italy has been the starting point of phenomena of international impact such as the Roman Republic , Roman Empire , the Roman Catholic Church , the Maritime republics , Romanesque art , Scholasticism , the Renaissance , the Age of Discovery , Mannerism , the Scientific revolution ,

5916-503: The Italians, is medieval and was used alternatively with Italicus during the early modern period . After the fall of the Western Roman Empire , which was caused by the invasion of the Ostrogoths , the Kingdom of Italy was created. After the Lombard invasions, "Italia" was retained as the name for their kingdom , and for its successor kingdom within the Holy Roman Empire , which nominally lasted until 1806, although it had de facto disintegrated due to factional politics pitting

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6032-404: The Middle Ages to the early modern period, with its intricate canal system attracts tourists from all over the world especially during the Venetian Carnival and the Biennale . Naples , with the largest historic city centre in Europe and the oldest continuously active public opera house in the world ( Teatro di San Carlo ). Bologna is the main transport hub of the country, as well as the home of

6148-550: The Papal Medical School and wrote a long treatise about his studies which he donated to the Royal Society of London. Marcello Malpighi died of apoplexy (an old-fashioned term for a stroke or stroke-like symptoms) in Rome on 30 November 1694, at the age of 66. In accordance with his wishes, an autopsy was performed. The Royal Society published his studies in 1696. Asteroid 11121 Malpighi is named in his honour. Italians Italians ( Italian : italiani , pronounced [itaˈljaːni] ) are an ethnic group native to

6264-399: The Pious succeeded him. Louis divided the empire among his sons, and Frankish Italy became part of Middle Francia , extending as far south as Rome and Spoleto . This Kingdom of Italy became part of the Holy Roman Empire in the 10th century, while southern Italy was under the rule of the Lombard Principality of Benevento or of the Byzantine Empire , in the 12th century absorbed into

6380-400: The Renaissance, Italy became an even more attractive prize to foreign conquerors. After some city-states asked for outside help in settling disputes with their neighbours, King Charles VIII of France marched into Italy in 1494; he soon withdrew, showing that the Italian peninsula's delicate equilibrium could be taken advantage of. After the Italian Wars , Spain emerged as the dominant force in

6496-445: The Romantic period, when its dominance in painting and sculpture diminished but the Italians re-established a strong presence in music. Italian explorers and navigators in the 15th and 16th centuries left a perennial mark on human history with the modern "discovery of America", due to the Genoese explorer Christopher Columbus . In addition, the name of " America " derives from the geographer Amerigo Vespucci 's first name. Also noted

6612-428: The Royal Society, Nehemiah Grew and Antoine van Leeuwenhoek were fortunate to have a virtually untried tool in their hands as they began their investigations. In 1661, Malpighi observed capillary structures in frog lungs. Malpighi's first attempt at examining circulation in the lungs was in September 1660, with the dissection of sheep and other mammals where he would inject black ink into the pulmonary artery. Tracing

6728-520: The age of 17. In a posthumous work delivered and dedicated to the Royal Society in London in 1697, Malpighi says he completed his grammatical studies in 1645, at which point he began to apply himself to the study of peripatetic philosophy. He completed these studies in about 1649, where at the persuasion of his mother Frances Natalis, he began to study physics. When his parents and grandmother became ill, he returned to his family home near Bologna to care for them. Malpighi studied Aristotelian philosophy at

6844-424: The alveoli at the ends of the pathway acting as a "imperfect sponge" for the air to enter the body. Extrapolating to humans, he offered an explanation for how air and blood mix in the lungs. Malpighi also used the microscope for his studies of the skin, kidneys, and liver. For example, after he dissected a black male, Malpighi made some groundbreaking headway into the discovery of the origin of black skin. He found that

6960-493: The anatomy of the brain and concluded this organ is a gland. In terms of modern endocrinology , this deduction is correct because the hypothalamus of the brain has long been recognized for its hormone-secreting capacity. Because Malpighi had a wide knowledge of both plants and animals, he made contributions to the scientific study of both. The Royal Society of London published two volumes of his botanical and zoological works in 1675 and 1679. Another edition followed in 1687, and

7076-540: The ancient Greeks in Magna Graecia , and the Phoenicians , who had a presence in Sicily and Sardinia , the Celts , who settled in parts of the north, the Germanics and the Slavs. Legally, Italian nationals are citizens of Italy , regardless of ancestry or nation of residence (in effect, however, Italian nationality is largely based on jus sanguinis ) and may be distinguished from ethnic Italians in general or from people of Italian descent without Italian citizenship and ethnic Italians living in territories adjacent to

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7192-616: The associated Romanization , culminated in 88 BC, when, in the aftermath of the Social War , Rome granted its fellow Italian allies full rights in Roman society , extending Roman citizenship to all fellow Italic peoples . From its inception, Rome was a republican city-state, but four famous civil conflicts destroyed the Roman Republic : Lucius Cornelius Sulla against Gaius Marius and his son (88–82 BC), Julius Caesar against Pompey (49–45 BC), Marcus Junius Brutus and Gaius Cassius Longinus against Mark Antony and Octavian (43 BC), and Mark Antony against Octavian . Octavian,

7308-405: The beginning of the 14th century. During the 14th and 15th centuries, some Italian city-states ranked among the most important powers of Europe. Venice, in particular, had become a major maritime power, and the city-states as a group acted as a conduit for goods from the Byzantine and Islamic empires. In this capacity, they provided great impetus to the developing Renaissance , began in Florence in

7424-401: The black pigment was associated with a layer of mucus just beneath the skin. In the years 1663–1667, at the University of Messina where his research focus was on studying the human nervous system where he identified and described nerve endings in the body, structure of the brain, and optic nerve. All of his work in 1665 surrounding the nervous system he published in 3 separate works published in

7540-401: The body could not have attempted to expel any malignant matter, such as vomit. Cases in which this did occur, when healing could not be considered miraculous, were known as "crises." In 1668, Malpighi received a letter from Mr. Oldenburg of the Royal Society in London, inviting him to correspond. Malpighi wrote his history of the silkworm in 1668, and sent the manuscript to Mr. Oldenburg. As

7656-485: The capital of the kingdom. Pope Pius IX , a longtime rival of Italian kings, stated he had been made a "prisoner" inside the Vatican walls and refused to cooperate with the royal administration. Only in 1929 did the Roman Pope accept the unified Italy with Rome as capital. World War I has been interpreted as completing the process of Italian unification, with the annexation of Trieste, Istria , Trentino-Alto Adige and Zara . After World War I, Italy emerged as one of

7772-420: The city was far from the troubled frontiers. The seats of the Caesars became Augusta Treverorum (on the River Rhine frontier) for Constantius Chlorus and Sirmium (on the River Danube frontier) for Galerius , who also resided at Thessaloniki . Under Diocletian, Italy became the Dioecesis Italiciana , subdivided into thirteen provinces, now including Raetia . Under Constantine the Great , Italy became

7888-414: The compound lens and inserted it in a microscope around the turn of the 17th century, and Galileo had applied the principle of the compound lens to the making of his microscope patented in 1609, its possibilities as a microscope had remained unexploited for half a century, until Robert Hooke improved the instrument. Following this, Marcello Malpighi, Hooke, and two other early investigators associated with

8004-403: The day. Family responsibilities and poor health prompted Malpighi's return in 1659 to the University of Bologna, where he continued to teach and do research with his microscopes. In 1661 he identified and described the pulmonary and capillary network connecting small arteries with small veins. Malpighi's views evoked increasing controversy and dissent, mainly from envy and lack of understanding on

8120-425: The dissection of corpses, his most illustrative efforts appear to have been based on the use of the microscope. Because of this work, many microscopic anatomical structures are named after Malpighi, including a skin layer (Malpighi layer) and two different Malpighian corpuscles in the kidneys and the spleen, as well as the Malpighian tubules in the excretory system of insects. Although a Dutch spectacle maker created

8236-544: The efforts of noblemen, emperors, and larger foreign powers to control them. The emergence of identifiable Italian dialects from Vulgar Latin , and as such the possibility of a specifically "Italian" ethnic identity, has no clear-cut date, but began in roughly the 12th century. Modern standard Italian derives from the written vernacular of Tuscan writers of the 12th century. The recognition of Italian vernaculars as literary languages in their own right began with De vulgari eloquentia , an essay written by Dante Alighieri at

8352-491: The empire against the ascendant city republics in the 13th century. The Italian peninsula was divided into a multitude of tribal or ethnic territory prior to the Roman conquest of Italy in the 3rd century BC. After a series of wars between Greeks and Etruscans , the Latins , with Rome as their capital, gained the ascendancy by 272 BC, and completed the conquest of the Italian peninsula by 218 BC. This period of unification

8468-508: The end of 1666, Malpighi was invited to return to the public academy at Messina, which he did in 1667. Although he accepted temporary chairs at the universities of Pisa and Messina , throughout his life he continuously returned to Bologna to practice medicine, a city that repaid him by erecting a monument in his memory after his death. As a physician, Malpighi's medical consultations with his patients, which were mostly those belonging to social elite classes, proved useful in better understanding

8584-466: The etymology of the Latin name "Italia" are numerous. One is that it was borrowed via Greek from the Oscan Víteliú 'land of calves' ( cf. Lat vitulus "calf", Umb vitlo "calf"). Greek historian Dionysius of Halicarnassus states this account together with the legend that Italy was named after Italus , mentioned also by Aristotle and Thucydides . According to Antiochus of Syracuse ,

8700-682: The expansion of the Roman Republic , the name was used by Greeks to indicate the land between the Strait of Messina and the line connecting the Gulf of Salerno and Gulf of Taranto , corresponding roughly to the current region of Calabria . The Greeks gradually came to apply the name "Italia" to a larger region In addition to the "Greek Italy" in the south, historians have suggested the existence of an "Etruscan Italy" covering variable areas of central Italy. The borders of Roman Italy are better established. Cato

8816-593: The fact that he practised in various countries. However, long distances complicated consults for some of his patients. The manner in which Malpighi practised medicine also reveals that it was customary in his time for Italian patients to have multiple attending physicians as well as consulting physicians. One of Malpighi's principles of medical practice was that he did not rely on anecdotes or experiences concerning remedies for various illnesses. Rather, he used his knowledge of human anatomy and disease pathology to practice what he denoted as "rational" medicine ("rational" medicine

8932-447: The final victor (31 BC), was accorded the title of Augustus by the Senate and thereby became the first Roman Emperor. Augustus created for the first time an administrative region called Italia with inhabitants called "Italicus populus", stretching from the Alps to Sicily : for this reason historians like Emilio Gentile called him Father of Italians . In the 1st century BC, Italia

9048-455: The first public performance of the song Il Canto degli Italiani , the Italian national anthem since 1946, took place. Il Canto degli Italiani , written by Goffredo Mameli set to music by Michele Novaro , is also known as the Inno di Mameli , after the author of the lyrics, or Fratelli d'Italia , from its opening line . The unification of Italy was brought to a successful conclusion under

9164-412: The frog's lungs, Malpighi studied the movement of the blood in a contained system. This contrasted the previous view of an open circulatory system in which blood would come from the liver/spleen and pool into open spaces in the body. This discovery of capillaries also contributed to William Harvey 's theory of blood circulation, with capillaries acting as the connection from veins to arteries and confirming

9280-519: The guidance of Camillo Benso, conte di Cavour , prime minister of Piedmont. Cavour managed to unite most of Italy under the headship of Victor Emmanuel II of the house of Savoy, and on 17 March 1861, the Kingdom of Italy was proclaimed with Victor Emmanuel II as king. Giuseppe Garibaldi , the popular republican hero of Italy, contributed much to this achievement with the Expedition of the Thousand and to

9396-413: The inks distribution through the artery to the veins in the animal's lungs however, the chosen sheep/mammal's large size was limiting for his observation of capillaries as they were too small for magnification. Malpighi's frog dissection in 1661, proved to be a suitable size that could be magnified to display the capillary network not seen in the larger animals. In discovering and observing the capillaries in

9512-456: The island of Sardinia, which had been ceded to the Alpine House of Savoy in 1720 and had remained under their rule ever since, were not under French control. French domination lasted less than 20 years, and it differed from previous foreign control of the Italian peninsula. In spite of heavy taxation and frequent harshness, the French introduced representative assemblies and new laws that were

9628-715: The largest Italian community outside Italy), more than 18 million Italian Americans , and people in other parts of Europe (e.g. Italians in Germany , Italians in France and Italians in the United Kingdom ), the American Continent (such as Italian Venezuelans , Italian Canadians , Italian Colombians and Italians in Paraguay , among others), Australasia ( Italian Australians and Italian New Zealanders ), and to

9744-486: The links between the human anatomy, disease pathology, and treatments for said diseases. Furthermore, Malpighi conducted his consultations not only by bedside, but also by post, using letters to request and conduct them for various patients. These letters served as social connections for the medical practices he performed, allowing his ideas to reach the public even in the face of criticism. These connections that Malpighi created in his practice became even more widespread due to

9860-454: The liquid, changing positions as the temperature rose or fell. Marked off with 360 divisions, like the gradations or "degrees" of a circle, this type of device was called a "spirit thermometer", because it was filled with "spirit of wine" (distilled alcohol), or a "Florentine thermometer". In 1657, Leopoldo de' Medici , the grand duke's youngest brother, established the Accademia del Cimento . It

9976-503: The lungs which led him to several disputes with the learned medical men of the times. In 1662, he was made a professor of physics at the Academy of Messina. Retiring from university life to his villa in the country near Bologna in 1663, he worked as a physician while continuing to conduct experiments on the plants and insects he found on his estate. There he made discoveries of the structure of plants which he published in his Observations . At

10092-448: The most popular in the world, its cinema (with filmmakers such as Federico Fellini , Michelangelo Antonioni , Mario Monicelli , Sergio Leone , etc.), its collections of priceless works of art and its fashion (Milan and Florence are regarded as some of the few fashion capitals of the world). National symbols of Italy are the symbols that uniquely identify Italy reflecting its history and culture . They are used to represent

10208-407: The outlines of a new Italy began to appear. Victor Emmanuel III gave up the throne on 9 May 1946, and his son, Umberto II , became king. On 2 June Italy held its first free election after 20 years of Fascist rule (the so-called Ventennio ). Italians chose a republic to replace the monarchy , which had been closely associated with Fascism . They elected a Constituent Assembly , which was formed by

10324-441: The part of his colleagues. In 1653, his father, mother, and grandmother being dead, Malpighi left his family villa and returned to the University of Bologna to study anatomy. In 1656, he was made a reader at Bologna, and then a professor of physics at Pisa, where he began to abandon the disputative method of learning and apply himself to a more experimental method of research. Based on this research, he wrote some Dialogues against

10440-408: The plant tissue. Malpighi's investigations of the lifecycle of plants and animals led him to the topic of reproduction. He created detailed drawings of his studies of chick embryo development, starting from 2–3 days after fertilization with these drawings of embryos having a focus on the developmental timing of the limbs and organs. Additionally, seed development in plants (such as the lemon tree), and

10556-454: The professorship of theoretical medicine at the University of Pisa . There Malpighi began his lifelong friendship with Giovanni Borelli , mathematician and naturalist, who was a prominent supporter of the Accademia del Cimento , one of the first scientific societies. Malpighi questioned the prevailing medical teachings at Pisa, tried experiments on colour changes in blood, and attempted to recast anatomical, physiological, and medical problems of

10672-545: The region. Venice, Milan, and other city-states retained at least some of their former greatness during this period, as did Savoy -Piedmont, protected by the Alps and well defended by its vigorous rulers. Italian explorers and navigators from the dominant maritime republics, eager to find an alternative route to the Indies in order to bypass the Ottoman Empire , offered their services to monarchs of Atlantic countries and played

10788-637: The representatives of all the anti-fascist forces that contributed to the defeat of Nazi and Fascist forces during the Italian Civil War , to prepare a new democratic constitution. The Assembly approved the new Italian constitution in 1947, which came into force on 1 January 1948. Under the Treaty of Peace with Italy, 1947 , Istria , Kvarner , most of the Julian March as well as the Dalmatian city of Zara

10904-537: The same for all parts of the country. For the first time since the days of ancient Rome, Italians of different regions used the same money and served in the same army. Many Italians began to see the possibility of a united Italy free of foreign control. During the Napoleonic era , in 1797, the first official adoption of the Italian tricolour as a national flag by a sovereign Italian state, the Cispadane Republic ,

11020-411: The same year titled, De Lingua about taste and the tongue, De Cerebro about the brain and De Externo Tactus Organo about feeling/touch sensation. In regards to his work on the tongue he discovered small muscle bumps, taste buds, which he called "papillae" and when examining them he described a linked connection to nerve endings that gave the taste sensation when eating. Furthermore, in 1686 through studying

11136-492: The service of France, renowned as the first European to explore the Atlantic coast of North America between Florida and New Brunswick in 1524. The French Revolution and Napoleon influenced Italy more deeply than they affected any other outside country of Europe. The French Revolution began in 1789 and immediately found supporters among the Italian people. The local Italian rulers, sensing danger in their own country, drew closer to

11252-787: The subsequent incorporation of the Papal States under the Italian monarch. Cavour handed Savoy and Nice over to France at the Treaty of Turin , a decision that was the consequence of the Plombières Agreement , on 24 March 1860, an event that caused the Niçard exodus , which was the emigration of a quarter of the Niçard Italians to Italy, and the Niçard Vespers . Italian troops occupied Rome in 1870, and in July 1871, this formally became

11368-539: The term Italy was used by the Greeks to initially refer only to the southern portion of the Bruttium peninsula corresponding to the modern province of Reggio and part of the provinces of Catanzaro and Vibo Valentia in Southern Italy . Nevertheless, by his time the larger concept of Oenotria and "Italy" had become synonymous and the name also applied to most of Lucania as well. According to Strabo 's Geographica , before

11484-556: The transformation of caterpillars into insects. Malpighi also postulated about the embryotic growth of humans, written in a letter to Girolamo Correr, a patron of scientists, Malphighi suggested that all the components of the circulatory system would have been developed at the same time in embryo . His discoveries helped to illuminate philosophical arguments surrounding the topics of emboîtment , pre-existence, preformation, epigenesis, and metamorphosis. In 1691 Pope Innocent XII invited him to Rome as papal physician. He taught medicine in

11600-433: The whole Italian geographical region . All its inhabitants were considered Italic and Roman . The Latin term Italicus was used to describe "a man of Italy" as opposed to a provincial . For example, Pliny the Elder notably wrote in a letter Italicus es an provincialis ? meaning "are you an Italian or a provincial?". The adjective italianus , from which are derived the Italian (and also French and English) name of

11716-410: The wide-ranging diaspora following Italian unification in 1861, World War I and World War II , (with over 5 million Italian citizens that live outside of Italy) over 80 million people abroad claim full or partial Italian ancestry. This includes about 60% of Argentina 's population ( Italian Argentines ), 1/3 of Uruguayans ( Italian Uruguayans ), 15% of Brazilians ( Italian Brazilians ,

11832-446: Was grand duke of Tuscany from 1621 to 1670. He was the eldest son of Cosimo II de' Medici and Maria Maddalena of Austria . Remembered by his contemporaries as a man of culture and science, he actively participated in the Accademia del Cimento , the first official scientific society in Italy, formed by his younger brother, Leopoldo de' Medici . His 49-year rule was punctuated by the beginning of Tuscany's long economic decline, which

11948-566: Was adopted by the Lombard Legion in 1796. The first red, white and green national flag of a sovereign Italian state was adopted on 7 January 1797, when the Fourteenth Parliament of the Cispadane Republic (1797), on the proposal of deputy Giuseppe Compagnoni , decreed "to make universal the ... standard or flag of three colours, green, white, and red ...": For having proposed the green, white and red tricolour flag, Giuseppe Compagnoni

12064-521: Was an outbreak of the plague that swept through Florence in 1630 and took 10% of the population with it. Unlike the Tuscan nobility, Ferdinando and his brothers stayed in the city to try to ameliorate the general suffering, traveling through the city on foot to help and encourage his subjects. Tuscany participated in the Wars of Castro , the last time Medicean Tuscany was involved in a military conflict and inflicted

12180-466: Was annexed by Yugoslavia causing the Istrian-Dalmatian exodus , which led to the emigration of between 230,000 and 350,000 of local ethnic Italians ( Istrian Italians and Dalmatian Italians ), the others being ethnic Slovenians, ethnic Croatians, and ethnic Istro-Romanians , choosing to maintain Italian citizenship . In 1949 Italy became a member of NATO . The Marshall Plan helped to revive

12296-465: Was deposed in 476 by a Germanic foederati general in Italy, Odoacer . His defeat marked the end of the Western Roman Empire , and the end of the political unification of Italy until the establishment of the modern Kingdom of Italy in 1861. Odoacer ruled well for 13 years after gaining control of Italy in 476. Then he was attacked and defeated by Theodoric , the king of another Germanic tribe,

12412-616: Was followed by one of conquest in the Mediterranean, beginning with the First Punic War against Carthage . In the course of the century-long struggle against Carthage, the Romans conquered Sicily, Sardinia and Corsica. Finally, in 146 BC, at the conclusion of the Third Punic War , with Carthage completely destroyed and its inhabitants enslaved, Rome became the dominant power in the Mediterranean. The process of Italian unification, and

12528-521: Was further exacerbated by his successor, Cosimo III de' Medici . He married Vittoria della Rovere , a first cousin, with whom he had two children who reached adulthood: the aforementioned Cosimo III, and Francesco Maria de' Medici, Duke of Rovere and Montefeltro , a cardinal . Ferdinando was only 10 years of age when his father Cosimo II died. Because he had not yet reached maturity, his mother Maria Maddalena and paternal grandmother, Christina of Lorraine , acted as joint regents. His two regents arranged

12644-661: Was in contrast to "empirics"). Malpighi did not abandon traditional substances or treatments, but he did not employ their use simply based on past experiences that did not draw from the nature of the underlying anatomy and disease process. Specifically in his treatments, Malpighi's goal was to reset fluid imbalances by coaxing the body to correct them on its own. For example, fluid imbalances should be fixed over time by urination and not by artificial methods such as purgatives and vesicants. In addition to Malpighi's "rational" approaches, he also believed in so-called "miraculous," or "supernatural" healing. For this to occur, though, he argued that

12760-478: Was legally merged into the administrative unit of Italy in 42 BC by the triumvir Octavian as a ratification of Julius Caesar 's unpublished acts ( Acta Caesaris ). Under Emperor Diocletian the Roman region called "Italia" was further enlarged with the addition in 292 AD of the three big islands of the western Mediterranean Sea : Sicily (with the Maltese archipelago ), Sardinia and Corsica , coinciding with

12876-577: Was set up to attract scientists from all over Tuscany to Florence for mutual study. Ferdinand, like his father before him, was a patron, ally, and friend of Galileo Galilei. Galileo dedicated his Dialogue Concerning the Two Chief World Systems to him. This work led to Galileo's second set of hearings before the Inquisition . Ferdinand attempted to keep the concerns of the Holy See from leading to

12992-707: Was still a collection of territories with different political statuses. Some cities, called municipia , had some independence from Rome, while others, the coloniae , were founded by the Romans themselves. Around 7 BC, Augustus divided Italy into eleven regiones . During the Crisis of the Third Century , the Roman Empire nearly collapsed under the combined pressures of invasions, military anarchy and civil wars, and hyperinflation. In 284, emperor Diocletian restored political stability. The importance of Rome declined, because

13108-542: Was the first European to set foot in "New Found Land" and explore parts of the North American continent in 1497; Amerigo Vespucci , sailing for Portugal, who first demonstrated in about 1501 that the New World (in particular Brazil) was not Asia as initially conjectured, but a fourth continent previously unknown to people of the Old World (the name of " America " derives from his first name ); and Giovanni da Verrazzano , at

13224-541: Was the heart of the Renaissance , a period of great achievements in the arts at the end of the Middle Ages. Other important cities include Turin , which used to be the capital of Italy, and is now one of the world's great centers of automobile engineering. Milan is the industrial and financial capital of Italy and one of the world's fashion capitals . Venice , former capital of a major financial and maritime power from

13340-462: Was the power behind the throne until her death in 1636. With his wife, Vittoria, he had two surviving children: Cosimo , in 1642, and Francesco Maria de' Medici , in 1660. The latter was the fruit of a brief reconciliation, as after the birth of Cosimo, the two became estranged; Vittoria caught Ferdinando in bed with a page, Count Bruto della Molera. In fact, Ferdinando sexual preferences went largely to men. The first calamity of Ferdinando's reign

13456-480: Was usually the popes who led attempts to protect Italy from invasion or to soften foreign rule. For about 200 years the popes opposed attempts by the Lombards, who had captured most of Italy, to take over Rome as well. The popes finally defeated the Lombards with the aid of two Frankish kings, Pepin the Short and Charlemagne . Using land won for them by Pepin in 756, the popes established political rule in what were called

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