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118-713: It was originally founded in 1909, called the Louisiana State Library Association, after a call for a statewide library group from the New Orleans Library Club. An initial meeting of thirty people was held at Tulane University in 1909 with the goal of increasing the number of trained librarians in the state and drafting library legislation. The main speaker was Chalmers Hadley president of the American Library Association . The LLA fell into some disorder during and after World War I, and

236-671: A Level 2 alert (practice enhanced precautions.) A Bayesian analysis of genotypes I and II has shown that genotype I accounts for virtually all the current infections in Brazil , Colombia , Venezuela , and Trinidad and Tobago , while genotype II accounted for all cases in Peru . Genotype I originated in the northern Brazilian region around 1908 (95% highest posterior density interval [HPD]: 1870–1936). Genotype II originated in Peru in 1920 (95% HPD: 1867–1958). The estimated rate of mutation for both genotypes

354-413: A polyprotein . Host proteases cut this polyprotein into three structural (C, prM, E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5); the enumeration corresponds to the arrangement of the protein coding genes in the genome . Minimal YFV 3 ′ UTR region is required for stalling of the host 5 ′ -3 ′ exonuclease XRN1. The UTR contains PKS3 pseudoknot structure, which serves as

472-450: A 21 percent increase over the last five years. The acceptance rate for the class of 2026 was 8.4 percent. The yield rate was 52 percent. Among freshman students who committed to enroll in Fall 2022, the average converted SAT score was 1474. Composite ACT scores for the middle 50% ranged from 31 to 34. The most impressive incoming undergraduate students are invited to join the honors program by

590-572: A College of Commerce, the first business school in the South . In 1925, Tulane established the independent Graduate School. Two years later, the university set up a School of Social Work , also the first in the southern United States. Tulane was instrumental in promoting the arts in New Orleans and the South in establishing the Newcomb School of Art with William Woodward as director, thus establishing

708-758: A WHO-approved vaccination center is required. Although 32 of 44 countries where yellow fever occurs endemically do have vaccination programmes, in many of these countries, less than 50% of their population is vaccinated. Control of the yellow fever mosquito A. aegypti is of major importance, especially because the same mosquito can also transmit dengue fever and chikungunya disease. A. aegypti breeds preferentially in water, for example, in installations by inhabitants of areas with precarious drinking water supplies, or in domestic refuse, especially tires, cans, and plastic bottles. These conditions are common in urban areas in developing countries. Two main strategies are employed to reduce A. aegypti populations. One approach

826-570: A billion people live in an area of the world where the disease is common. It is common in tropical areas of the continents of South America and Africa, but not in Asia. Since the 1980s, the number of cases of yellow fever has been increasing. This is believed to be due to fewer people being immune, more people living in cities, people moving frequently, and changing climate increasing the habitat for mosquitoes. The disease originated in Africa and spread to

944-464: A biopsy is only advisable post mortem to confirm the cause of death. In a differential diagnosis , infections with yellow fever must be distinguished from other feverish illnesses such as malaria . Other viral hemorrhagic fevers , such as Ebola virus , Lassa virus , Marburg virus , and Junin virus , must be excluded as the cause. Personal prevention of yellow fever includes vaccination and avoidance of mosquito bites in areas where yellow fever

1062-479: A commitment to reduce greenhouse gas emissions by 10%, getting students involved by providing an Energy Smart Shopping Guide and electronics "greening" services from IT. In 2010 Tulane completed its renovation of 88-year-old Dinwiddie Hall, which was subsequently LEED Gold certified. A new residential college, Weatherhead Hall, opened in 2011 as housing for sophomore honors students. The residence has also applied for LEED Gold certification. Tulane received an "A−" on

1180-498: A course credit involving service learning became a requirement for an undergraduate degree. In 2006 Tulane became the first Carnegie ranked "high research activity" institution to have an undergraduate public service graduation requirement. In May 2006, graduation ceremonies included commencement speakers former Presidents George H. W. Bush and Bill Clinton , who commended the students for their desire to return to Tulane and serve New Orleans in its renewal. Tulane's primary campus

1298-442: A molecular signal to stall the exonuclease and is the only viral requirement for subgenomic flavivirus RNA (sfRNA) production. The sfRNAs are a result of incomplete degradation of the viral genome by the exonuclease and are important for viral pathogenicity. Yellow fever belongs to the group of hemorrhagic fevers . The viruses infect, amongst others, monocytes , macrophages , Schwann cells , and dendritic cells . They attach to

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1416-493: A rearrangement of the 90 homo dimers to 60 homo trimers . After entering the host cell, the viral genome is replicated in the rough endoplasmic reticulum (ER) and in the so-called vesicle packets. At first, an immature form of the virus particle is produced inside the ER, whose M-protein is not yet cleaved to its mature form, so is denoted as precursor M (prM) and forms a complex with protein E. The immature particles are processed in

1534-549: A reduced volume of vaccine dose, which has been reconstituted as per manufacturer recommendations. The first practical use of fractional dose yellow fever vaccination was in response to a large yellow fever outbreak in the Democratic Republic of the Congo in mid-2016. Available evidence shows that fractional dose yellow fever vaccination induces a level of immune response similar to that of the standard full dose. In March 2017,

1652-421: Is common in tropical and subtropical areas of South America and Africa. Worldwide, about 600 million people live in endemic areas. The WHO estimates 200,000 cases of yellow fever worldwide each year. About 15% of people infected with yellow fever progress to a severe form of the illness, and up to half of those will die, as there is no cure for yellow fever. An estimated 90% of yellow fever infections occur on

1770-431: Is caused by yellow fever virus (YFV), an enveloped RNA virus 40–50 nm in width, the type species and namesake of the family Flaviviridae . It was the first illness shown to be transmissible by filtered human serum and transmitted by mosquitoes, by American doctor Walter Reed around 1900. The positive- sense , single-stranded RNA is around 10,862 nucleotides long and has a single open reading frame encoding

1888-604: Is deemed a "Most Selective" university. Tulane is the only institution in Louisiana to have that distinction. The school accepts the Common Application for admission. Tulane has the second lowest percentage of Pell Grant recipients in the United States, only after Fairfield University . It is need-blind for domestic applicants. The Office of Undergraduate Admission received over 43,000 applications for fall 2022 — over

2006-524: Is directly adjacent to Tulane, on the downriver side. Audubon Place , where the President of Tulane resides, is on the upriver side. The President's residence is the former home of "banana king" Sam Zemurray , who donated it in his will. The centerpiece of the Gibson Quad is the first academic building built on campus, Gibson Hall , in 1894. The School of Architecture is also located on the oldest section of

2124-625: Is endemic. Institutional measures for prevention of yellow fever include vaccination programmes and measures to control mosquitoes. Programmes for distribution of mosquito nets for use in homes produce reductions in cases of both malaria and yellow fever. Use of EPA-registered insect repellent is recommended when outdoors. Exposure for even a short time is enough for a potential mosquito bite. Long-sleeved clothing, long pants, and socks are useful for prevention. The application of larvicides to water-storage containers can help eliminate potential mosquito breeding sites. EPA-registered insecticide spray decreases

2242-643: Is fatal in 60% of cases. It is probably due to the genetic morphology of the immune system. Another possible side effect is an infection of the nervous system, which occurs in one in 200,000 to 300,000 cases, causing yellow fever vaccine-associated neurotropic disease, which can lead to meningoencephalitis and is fatal in less than 5% of cases. The Yellow Fever Initiative, launched by the WHO in 2006, vaccinated more than 105 million people in 14 countries in West Africa. No outbreaks were reported during 2015. The campaign

2360-663: Is for students enrolled in full-time study toward a Master's Degree in Library Science at Louisiana State University School of Library and Information Science. The Mary Moore Mitchell Scholarship is for part-time study. Recipients of both scholarships are selected by the Scholarship Committee with advice of the faculty at the Louisiana State University School of Library and Information Science. Tulane University Tulane University , officially

2478-504: Is known as acquired immunity . The virus, as well as the vector A. aegypti, were probably transferred to North and South America with the trafficking of slaves from Africa, part of the Columbian exchange following European exploration and colonization. However, some researchers have argued that yellow fever might have existed in the Americas during the pre-Columbian period as mosquitoes of

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2596-571: Is located in Uptown New Orleans on St. Charles Avenue , directly opposite Audubon Park , and extends north to South Claiborne Avenue through Freret and Willow Street. The campus is known colloquially as the Uptown or St. Charles campus. It was established in the 1890s and occupies more than 110 acres (0.45 km ) of land. The campus is known both for its large live oak trees as well as its architecturally historic buildings. It has been listed on

2714-470: Is not recommended by the WHO. Insecticide-treated mosquito nets are effective, just as they are against the Anopheles mosquito that carries malaria. As with other Flavivirus infections, no cure is known for yellow fever. Hospitalization is advisable and intensive care may be necessary because of rapid deterioration in some cases. Certain acute treatment methods lack efficacy: passive immunization after

2832-410: Is recommended as a chemical larvicide, mainly because it is safe for humans and effective in small doses. The second strategy is to reduce populations of the adult yellow fever mosquito. Lethal ovitraps can reduce Aedes populations, using lesser amounts of pesticide because it targets the pest directly. Curtains and lids of water tanks can be sprayed with insecticides, but application inside houses

2950-536: Is spread primarily by Aedes aegypti , a type of mosquito found throughout the tropics and subtropics . The virus is an RNA virus of the genus Flavivirus . The disease may be difficult to tell apart from other illnesses, especially in the early stages. To confirm a suspected case, blood-sample testing with a polymerase chain reaction is required. A safe and effective vaccine against yellow fever exists, and some countries require vaccinations for travelers. Other efforts to prevent infection include reducing

3068-427: Is taken up by a female mosquito when it ingests the blood of an infected human or another primate. Viruses reach the stomach of the mosquito, and if the virus concentration is high enough, the virions can infect epithelial cells and replicate there. From there, they reach the haemocoel (the blood system of mosquitoes) and from there the salivary glands . When the mosquito next sucks blood, it injects its saliva into

3186-543: Is the absence of a slave trade to Asia on the scale of that to the Americas. The trans-Atlantic slave trade probably introduced yellow fever into the Western Hemisphere from Africa. The evolutionary origins of yellow fever most likely lie in Africa, with transmission of the disease from nonhuman primates to humans. The virus is thought to have originated in East or Central Africa and spread from there to West Africa. As it

3304-507: Is to kill the developing larvae. Measures are taken to reduce the water accumulations in which the larvae develop. Larvicides are used, along with larvae-eating fish and copepods , which reduce the number of larvae. For many years, copepods of the genus Mesocyclops have been used in Vietnam for preventing dengue fever. This eradicated the mosquito vector in several areas. Similar efforts may prove effective against yellow fever. Pyriproxyfen

3422-468: The Civil War . The closing affected the first semester of the school calendar year. The School of Public Health and Tropical Medicine's distance learning programs and courses stayed active. The School of Medicine relocated to Houston , Texas for a year. Aside from student-athletes attending college classes together on the same campuses, most undergraduate and graduate students dispersed to campuses throughout

3540-545: The Golgi apparatus by the host protein furin , which cleaves prM to M. This releases E from the complex, which can now take its place in the mature, infectious virion . Yellow fever virus is mainly transmitted through the bite of the yellow fever mosquito Aedes aegypti , but other mostly Aedes mosquitoes such as the tiger mosquito ( Aedes albopictus ) can also serve as a vector for this virus. Like other arboviruses , which are transmitted by mosquitoes, yellow fever virus

3658-684: The Napoleonic Wars , the West Indies were known as a particularly dangerous posting for soldiers due to yellow fever being endemic in the area. The mortality rate in British garrisons in Jamaica was seven times that of garrisons in Canada, mostly because of yellow fever and other tropical diseases. Both English and French forces posted there were seriously affected by the "yellow jack." Wanting to regain control of

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3776-604: The Tulane School of Professional Advancement . Tulane has several academic and research institutes and centers including The Murphy Institute , Newcomb College Center for Research on Women, The Roger Thayer Stone Center for Latin American Studies, the Middle American Research Institute, and the law school's Payson Center for International Development . As part of the post-Hurricane Katrina Renewal Plan,

3894-726: The Tulane University of Louisiana , is a private research university in New Orleans , Louisiana , United States. Founded as the Medical College of Louisiana in 1834 by a cohort of medical doctors, it became a comprehensive public university in the University of Louisiana in 1847. The institution became private under the endowments of Paul Tulane and Josephine Louise Newcomb in 1884 and 1887. The Tulane University Law School and Tulane University Medical School are, respectively,

4012-524: The V-12 Navy College Training Program which offered students a path to a Navy commission. In 1963, Tulane enrolled its first African American students. In 1990, Rhonda Goode-Douglas, alongside other black, female students, founded the first African American sorority in Tulane's history, AKA Omicron Psi. A detailed account of the history of Tulane University from its founding through 1965

4130-488: The 12th oldest law school and 15th oldest medical school in the United States. Tulane has been a member of the Association of American Universities since 1958 and is classified among "R1: Doctoral Universities – Very high research activity". Alumni include twelve governors of Louisiana ; one Chief Justice of the United States ; various members of Congress, including a Speaker of the U.S. House ; two Surgeons General of

4248-587: The 2011 College Sustainability Report Card , garnering an award as one of the top 52 most sustainable colleges in the country. Tulane University, as a private institution, has been governed since 1884 by the Board of Tulane (also known as the Board of Administrators of the Tulane Educational Fund) that was established in 1882. There have been 15 presidents of Tulane since then. The board comprises more than 30 regular members (plus several members emeriti) and

4366-653: The African continent. In 2016, a large outbreak originated in Angola and spread to neighboring countries before being contained by a massive vaccination campaign. In March and April 2016, 11 imported cases of the Angola genotype in unvaccinated Chinese nationals were reported in China, the first appearance of the disease in Asia in recorded history. Phylogenetic analysis has identified seven genotypes of yellow fever viruses, and they are assumed to be differently adapted to humans and to

4484-521: The Americas starting in the 17th century with the European trafficking of enslaved Africans from sub-Saharan Africa. Since the 17th century, several major outbreaks of the disease have occurred in the Americas, Africa, and Europe. In the 18th and 19th centuries, yellow fever was considered one of the most dangerous infectious diseases ; numerous epidemics swept through major cities of the US and in other parts of

4602-583: The COVID-19 pandemic. The Lavin-Bernick Center for University Life (LBC) was renovated to be a green, environmentally friendly building and opened for student use in January 2007. In 2009, the university altered McAlister Drive, a street that ran through the middle of the uptown campus into a pedestrian walkway renamed McAlister Place. The area was resurfaced, and the newly added green spaces were adorned with Japanese magnolias, irises and new lighting. In late November 2008

4720-625: The City of New Orleans announced plans to add bicycle lanes to the St. Charles Avenue corridor that runs in front of campus. In 2019, a new student space located in the middle of the uptown campus, The Malkin Sacks Commons, was opened by President Mike Fitts. The Commons is the central dining area on campus. Catering to most dietary restrictions, The Commons directly connects to the Lavin-Bernick Center on

4838-620: The College of Technology, the Tulane School of Architecture was separately formed as a school in 1953. The A.B. Freeman School of Business was named in honor of Alfred Bird Freeman, former chair of the Louisiana Coca-Cola Bottling Co. and a prominent New Orleans philanthropist and civic leader. The business school is ranked 44th nationally and 28th among programs at private universities by Forbes magazine. U.S. News & World Report' s Best Graduate Schools 2015 edition ranked

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4956-523: The Democratic Republic of Congo (2016), Uganda (2016), and more recently in Nigeria and Brazil in 2017 have further increased demand, while straining global vaccine supply. Therefore, to vaccinate susceptible populations in preventive mass immunization campaigns during outbreaks, fractional dosing of the vaccine is being considered as a dose-sparing strategy to maximize limited vaccine supplies. Fractional dose yellow fever vaccination refers to administration of

5074-790: The East African genotype, which had remained undetected in the previous 40 years. In South America, two genotypes have been identified (South American genotypes I and II). Based on phylogenetic analysis these two genotypes appear to have originated in West Africa and were first introduced into Brazil. The date of introduction of the predecessor African genotype which gave rise to the South American genotypes appears to be 1822 (95% confidence interval 1701 to 1911). The historical record shows an outbreak of yellow fever occurred in Recife, Brazil, between 1685 and 1690. The disease seems to have disappeared, with

5192-606: The Health Sciences campus are also involved in community-wide health promotion, such as community health fairs and distributing condoms to address the high rate of STIs in New Orleans. In 2014, the Tulane School of Social Work relocated from the Uptown campus to the Health Sciences campus, with facilities located in a renovated historic building on Elk Place. Tulane University Square consists of 80,000 square feet (7,400 m ) of space and 6 acres (24,000 m ) of surrounding land located on Broadway and Leake Avenue adjacent to

5310-504: The MBA program 63rd overall. The Tulane University Law School , established in 1847, is the 12th oldest law school in the United States. In 1990, it became the first law school in the United States to mandate pro bono work as a graduation requirement. U.S. News & World Report ' s 2015 edition ranked the School of Law 46th overall and 6th in environmental law, while the 2022 edition ranked

5428-654: The Mississippi River. Outside of New Orleans, the Tulane National Primate Research Center in Covington, Louisiana is one of eight such centers funded by the National Institutes of Health . The F. Edward Hebert Research Center near Belle Chasse, Louisiana provides facilities for graduate training and research in computer science , bioengineering , and biology . Satellite campuses of

5546-511: The National Register of Historic Places since 1978. The campus architecture consists of several styles, including Richardsonian Romanesque , Elizabethan, Italian Renaissance , Mid-Century Modern, and contemporary styles. The front campus buildings use Indiana White Limestone or orange brick for exteriors, while the middle campus buildings are mostly adorned in red St. Joe brick, the staple of Newcomb College Campus buildings. Loyola University

5664-484: The Newcomb-Tulane College (NTC) created programming for First Year Honors Scholars and phased out its honors program. Many of the components of the honors program have been incorporated into other NTC programs. Yellow fever Yellow fever is a viral disease of typically short duration . In most cases, symptoms include fever , chills , loss of appetite , nausea , muscle pains—particularly in

5782-513: The Office of Admission. Incoming freshmen who did not receive an invitation are allowed to apply for one after completing their first semester with at least a 3.8 cumulative GPA. To remain in good standing with the honors program, honors students are required to maintain at least a 3.8 cumulative GPA and enroll in honors classes their first year in the program. Honors students have access to special privileges and learning opportunities on campus. In 2021,

5900-979: The School of Continuing Studies, Tulane's open admissions school of continuing studies , are located in downtown New Orleans, in Elmwood, Louisiana , and in Biloxi, Mississippi . From 2010 to 2017, Tulane also operated a satellite campus in Madison, Mississippi . Tulane offers an executive MBA program in Cali, Colombia ; Santiago, Chile ; Shanghai, China ; and Taipei, Taiwan . Tulane hosted an Environmental Summit at its law school in April 2009, an event that all students could attend for free. Many students from Tulane's two active environmental groups, Green Club and Environmental Law Society, attended. These student groups push for global citizenship and environmental stewardship on campus. In 2007 Tulane made

6018-490: The School of Hygiene and Tropical Medicine was not established until 1912 as a separate entity from the College of Medicine. In 1919 the separate school ceased to be an independent unit and was merged with the College of Medicine. By 1967 the School of Public Health and Tropical Medicine reestablished as a separate academic unit of Tulane. In the fall of 2006, the School of Public Health began admitting undergraduate students. The Tulane University School of Science and Engineering

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6136-399: The School of Law 60th overall. "The Law School 100" ranks Tulane as 34th, relying on a qualitative (rather than quantitative) assessment. The 2010 Leiter law-school rankings put Tulane at 38th, based on student quality, using LSAT and GPA data. The Hylton law-school rankings , conducted in 2006, put Tulane at 39th. The school's maritime law program is widely considered to be the best in

6254-474: The TEF in 1884. This act created the Tulane University of Louisiana . The university was privatized, and is one of only a few American universities to be converted from a state public institution to a private one. Paul Tulane's endowment to the school specified that the institution could only admit white students, and Louisiana law passed in 1884 reiterated this condition. In 1884, William Preston Johnston became

6372-535: The U.S. The storm inflicted more than $ 650 million in damages to the university, with some of the greatest losses impacting the Howard-Tilton Memorial Library and its collections. Facing a budget shortfall, the Board of Administrators announced a "Renewal Plan" in December 2005 to reduce its annual operating budget and create a "student-centric" campus. Addressing the school's commitment to New Orleans,

6490-564: The US representative of Louisiana's 1st Congressional District. During the historic speech, Ford announced that the Vietnam War was "finished as far as America is concerned" one week before the fall of Saigon . Ford drew parallels to the Battle of New Orleans and said that such positive activity could do for America's morale what the battle did in 1815. During World War II , Tulane was one of 131 colleges and universities nationally that took part in

6608-408: The United States ; 23 Marshall Scholars ; 18 Rhodes Scholars ; 15 Truman Scholars ; 155 Fulbright Scholars ; four living billionaires; and a former President of Costa Rica . Two Nobel laureates have been affiliated with the university. The university was founded as the Medical College of Louisiana in 1834 partly as a response to the fears of smallpox , yellow fever , and cholera in

6726-524: The United States, with the Tulane Maritime Law Journal being the paramount admiralty law journal of the country. In May 2007, Tulane Law announced a Strategic Plan to increase student selectivity by gradually reducing the incoming JD class size from a historical average of 350 students per year to a target of 250 students per year within several years. The School of Liberal Arts encompasses 16 departments and 19 interdisciplinary programs in

6844-406: The United States. The university became the second medical school in the South, and the 15th in the United States at the time. In 1847, the state legislature established the school as the University of Louisiana , a public university , and the law department was added to the university. Subsequently, in 1851, the university established its first academic department. The first president chosen for

6962-514: The WHO launched a vaccination campaign in Brazil with 3.5 million doses from an emergency stockpile. In March 2017 the WHO recommended vaccination for travellers to certain parts of Brazil. In March 2018, Brazil shifted its policy and announced it planned to vaccinate all 77.5 million currently unvaccinated citizens by April 2019. Some countries in Asia are considered to be potentially in danger of yellow fever epidemics, as both mosquitoes with

7080-409: The WHO on 17 May 2013 advised that subsequent booster vaccinations are unnecessary, an older (than 10 years) certificate may not be acceptable at all border posts in all affected countries. A list of the countries that require yellow fever vaccination is published by the WHO. If the vaccination cannot be given for some reason, dispensation may be possible. In this case, an exemption certificate issued by

7198-486: The back—and headaches . Symptoms typically improve within five days. In about 15% of people, within a day of improving the fever comes back, abdominal pain occurs, and liver damage begins causing yellow skin . If this occurs, the risk of bleeding and kidney problems is increased. The disease is caused by the yellow fever virus and is spread by the bite of an infected mosquito . It infects humans, other primates , and several types of mosquitoes. In cities, it

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7316-530: The campus, occupying the Richardson Memorial Building. The middle of the campus, between Feret and Willow Streets, and bisected by McAlister Place and Newcomb Place, serves as the center of campus activities. The Lavin-Bernick Center for University Life, Devlin Fieldhouse , McAlister Auditorium, Howard-Tilton Memorial Library , and most of the student residence halls and academic buildings populate

7434-407: The capability to transmit yellow fever as well as susceptible monkeys are present. The disease does not yet occur in Asia. To prevent introduction of the virus, some countries demand previous vaccination of foreign visitors who have passed through yellow fever areas. Vaccination has to be proved by a vaccination certificate, which is valid 10 days after the vaccination and lasts for 10 years. Although

7552-399: The cell surfaces via specific receptors and are taken up by an endosomal vesicle . Inside the endosome , the decreased pH induces the fusion of the endosomal membrane with the virus envelope . The capsid enters the cytosol , decays, and releases the genome. Receptor binding, as well as membrane fusion, are catalyzed by the protein E, which changes its conformation at low pH, causing

7670-598: The center of campus. The Howard-Tilton Memorial Library is located on Freret Street . It was under construction from 2013 to 2016, but it now has two additional floors, as well as a Rare Books room. The facilities for the Freeman School of Business line McAlister Place and sit next to the Tulane University Law School . The center of campus is also home to the historic Newcomb College Campus, which sits between Newcomb Place and Broadway. The Newcomb campus

7788-645: The change. The history of the association under Jim Crow has been documented by Alma Dawson in "The Participation of African Americans in the Louisiana Library Association." Before 1965 the Louisiana Colored Teachers’ Association (later called the Louisiana Education Association) had a libraries section which counted public, school, and academic librarians among its members. In 1992 a joint conference

7906-601: The demolition of Phelps Hall and Irby Hall. Weatherhead Hall was completed in 2011, and it now houses sophomore students. Construction on Greenbaum House, a Residential College in the Newcomb Campus area, began in January 2013 and was completed by Summer 2014. The Lallage Feazel Wall Residential College was completed in August 2005 and took in its first students when Tulane re-opened in January 2006. Usually an honors dorm, Wall began accommodating students of all academic standings during

8024-426: The detection of IgM or a four-fold increase in IgG titer is considered sufficient indication for yellow fever. As these tests can cross-react with other flaviviruses, such as dengue virus , these indirect methods cannot conclusively prove yellow fever infection. Liver biopsy can verify inflammation and necrosis of hepatocytes and detect viral antigens . Because of the bleeding tendency of yellow fever patients,

8142-562: The disease by the name "yellow fever" occurred in 1744. However, Dr. Mitchell misdiagnosed the disease that he observed and treated, and the disease was probably Weil's disease or hepatitis. McNeill argues that the environmental and ecological disruption caused by the introduction of sugar plantations created the conditions for mosquito and viral reproduction, and subsequent outbreaks of yellow fever. Deforestation reduced populations of insectivorous birds and other creatures that fed on mosquitoes and their eggs. In Colonial times and during

8260-498: The disease can only be confirmed virologically. Since mild cases of yellow fever can also contribute significantly to regional outbreaks, every suspected case of yellow fever (involving symptoms of fever, pain, nausea, and vomiting 6–10 days after leaving the affected area) is treated seriously. If yellow fever is suspected, the virus cannot be confirmed until 6–10 days following the illness. A direct confirmation can be obtained by reverse transcription polymerase chain reaction , where

8378-417: The disease characterized by recurring fever, this time accompanied by jaundice due to liver damage , as well as abdominal pain . Bleeding in the mouth, nose, eyes, and the gastrointestinal tract cause vomit containing blood , hence one of the names in Spanish for yellow fever, vómito negro ("black vomit"). There may also be kidney failure, hiccups, and delirium. Among those who develop jaundice,

8496-561: The downtown New Orleans Central Business District between the Mercedes-Benz Superdome and Canal Street in 18 mid/high-rise buildings, which house the School of Medicine, the School of Public Health and Tropical Medicine, and the main campus of the Tulane Medical Center . In addition to medical and public health education, the Health Sciences campus is the central location for biomedical research. Students and faculty from

8614-493: The emergence of symptoms is probably without effect; ribavirin and other antiviral drugs , as well as treatment with interferons , are ineffective in yellow fever patients. Symptomatic treatment includes rehydration and pain relief with drugs such as paracetamol (acetaminophen). However, aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) are often avoided because of an increased risk of gastrointestinal bleeding due to their anticoagulant effects. Yellow fever

8732-579: The establishment of the H. Sophie Newcomb Memorial College within Tulane University. Newcomb was the first coordinate college for women in the United States and became a model for such institutions as Pembroke College and Barnard College . In 1894 the College of Technology formed, which would later become the School of Engineering. In the same year, the university moved to its present-day uptown campus on historic St. Charles Avenue , five miles (8 km) by streetcar from downtown New Orleans. With

8850-500: The fatality rate is 20 to 50%, while the overall fatality rate is about 3 to 7.5%. Severe cases may have a mortality rate greater than 50%. Surviving the infection provides lifelong immunity , and normally results in no permanent organ damage. Yellow fever can lead to death for 20% to 50% of those who develop severe disease. Jaundice, fatigue, heart rhythm problems, seizures and internal bleeding may also appear as complications of yellow fever during recovery time. Yellow fever

8968-421: The first major center in the U.S. to focus on research using adult stem cells . The school has highly selective admissions, accepting only 175 medical students from more than 10,000 applications. It comprises 20 academic departments. The Tulane University School of Public Health and Tropical Medicine is the first public health school established in the U.S. Although a program in hygiene was initiated in 1881,

9086-463: The first president of Tulane. He had succeeded Robert E. Lee as president of Washington and Lee University after Lee's death. He had moved to Louisiana and become president of Louisiana State University in 1880. In 1885, the university established its graduate division, later becoming the Graduate School. One year later, gifts from Josephine Louise Newcomb totaling over $ 3.6 million, led to

9204-441: The genome of the virus is amplified. Another direct approach is the isolation of the virus and its growth in cell culture using blood plasma ; this can take 1–4 weeks. Serologically, an enzyme-linked immunosorbent assay during the acute phase of the disease using specific IgM against yellow fever or an increase in specific IgG titer (compared to an earlier sample) can confirm yellow fever. Together with clinical symptoms,

9322-607: The genus Haemagogus , which is indigenous to the Americas, have been known to carry the disease. The first definitive outbreak of yellow fever in the New World was in 1647 on the island of Barbados . An outbreak was recorded by Spanish colonists in 1648 in the Yucatán Peninsula , where the indigenous Mayan people called the illness xekik ("blood vomit"). In 1685, Brazil suffered its first epidemic in Recife . The first mention of

9440-632: The improvements to Tulane University in the late 19th century, Tulane had a firm foundation to build upon as the premier university of the Deep South and continued the legacy with growth in the 20th century. During 1907, the school established a four-year professional curriculum in architecture through the College of Technology, growing eventually into the Tulane School of Architecture . One year later, Schools of Dentistry and Pharmacy were established, albeit temporarily. The School of Dentistry ended in 1928, and Pharmacy six years later. In 1914, Tulane established

9558-441: The jungle and urban cycles. Different mosquitoes of the genus Aedes are involved. In recent years, this has been the most common form of transmission of yellow fever in Africa. Concern exists about yellow fever spreading to southeast Asia, where its vector A. aegypti already occurs. After transmission from a mosquito, the viruses replicate in the lymph nodes and infect dendritic cells in particular. From there, they reach

9676-471: The leading research universities in North America. The School of Public Health and Tropical Medicine again became independent from the School of Medicine in 1967. It was established in 1912. Tulane's School of Tropical Medicine also remains the only one of its kind in the country. On April 23, 1975, US President Gerald Ford spoke at Tulane University's Fogelman Arena at the invitation of F. Edward Hebert ,

9794-468: The liver and infect hepatocytes (probably indirectly via Kupffer cells ), which leads to eosinophilic degradation of these cells and to the release of cytokines . Apoptotic masses known as Councilman bodies appear in the cytoplasm of hepatocytes. Fatality may occur when cytokine storm , shock , and multiple organ failure follow. Yellow fever is most frequently a clinical diagnosis , based on symptomatology and travel history. Mild cases of

9912-475: The lucrative sugar trade in Saint-Domingue (Hispaniola), and with an eye on regaining France's New World empire, Napoleon sent an army under the command of his brother-in-law General Charles Leclerc to Saint-Domingue to seize control after a slave revolt. The historian J. R. McNeill asserts that yellow fever accounted for about 35,000 to 45,000 casualties of these forces during the fighting. Only one-third of

10030-542: The new university was Francis Lister Hawks , an Episcopal priest and prominent citizen of New Orleans at the time. The university was closed from 1861 to 1865 during the American Civil War . After reopening, it went through a period of financial challenges because of an extended agricultural depression in the South which affected the nation's economy. Paul Tulane , owner of a prospering dry goods and clothing business, donated extensive real estate within New Orleans for

10148-469: The next outbreak occurring in 1849. It was likely introduced with the trafficking of slaves through the slave trade from Africa. Genotype I has been divided into five subclades, A through E. In late 2016, a large outbreak began in Minas Gerais state of Brazil that was characterized as a sylvatic or jungle epizootic . Real-time phylogenetic investigations at the epicentre of the outbreak revealed that

10266-481: The only way unvaccinated humans can become infected, which explains the low incidence of yellow fever cases on the continent. People who become infected in the jungle can carry the virus to urban areas, where A. aegypti acts as a vector. Because of this sylvatic cycle, yellow fever cannot be eradicated except by completely eradicating the mosquitoes that serve as vectors. In Africa, a third infectious cycle known as "savannah cycle" or intermediate cycle, occurs between

10384-478: The outbreak was caused by the introduction of a virus lineage from the Amazon region into the southeast region around July 2016, spreading rapidly across several neotropical monkey species, including brown howler monkeys, which serve as a sentinel species for yellow fever. No cases had been transmitted between humans by the A. aegypti mosquito, which can sustain urban outbreaks that can spread rapidly. In April 2017,

10502-588: The population of the transmitting mosquitoes. In areas where yellow fever is common, early diagnosis of cases and immunization of large parts of the population are important to prevent outbreaks . Once a person is infected, management is symptomatic; no specific measures are effective against the virus. Death occurs in up to half of those who get severe disease. In 2013, yellow fever was estimated to have caused 130,000 severe infections and 78,000 deaths in Africa. Approximately 90 percent of an estimated 200,000 cases of yellow fever per year occur in Africa. Nearly

10620-433: The remaining two weeks. In June 2024, non-tenure track faculty at Tulane voted to form Tulane Workers United, the first higher education faculty union in the state of Louisiana. The union is formally affiliated with Workers United and SEIU . As a result of Hurricane Katrina in August 2005 and its damaging effects on New Orleans, most of the university was closed for the second time in its history—the first being during

10738-414: The renowned Newcomb Pottery . The Middle American Research Institute was established in 1925 at Tulane "for the purpose of advanced research into the history (both Indian and colonial), archaeology, tropical botany (both economic and medical), the natural resources and products, of the countries facing New Orleans across the waters to the south; to gather, index and disseminate data thereupon; and to aid in

10856-517: The second floor, and on its third floor houses the Newcomb Institute. There is one graduate housing complex for Tulane University, Bertie M. and John W. Deming Pavilion, in the Downtown Campus. As of 2016 it is not operated by the university's Department of Housing and Residence Life. There were previously two other complexes: The Tulane University Health Sciences campus is located in

10974-630: The social sciences, humanities, and fine and performing arts—including 50 undergraduate majors and two dozen M.A., M.F.A., and Ph.D. programs—plus the Shakespeare Festival, Summer Lyric Theatre, Carroll Gallery, Tulane Marching Band, and the Middle America Research Institute. The School of Liberal Arts is the largest of Tulane's nine schools with the greatest number of enrolled students, faculty members, majors, minors, and graduate programs. The Tulane University School of Medicine

11092-468: The support of education. This donation led to the establishment of a Tulane Educational Fund (TEF), whose board of administrators sought to support the University of Louisiana instead of establishing a new university. In response, through the influence of former Confederate general Randall Lee Gibson , the Louisiana state legislature transferred control of the University of Louisiana to the administrators of

11210-562: The sylvatic outbreak continued moving toward the Brazilian coast, where most people were unvaccinated. By the end of May the outbreak appeared to be declining after more than 3,000 suspected cases, 758 confirmed and 264 deaths confirmed to be yellow fever. The Health Ministry launched a vaccination campaign and was concerned about spread during the Carnival season in February and March. The CDC issued

11328-505: The transmission of yellow fever. Vaccination is recommended for those traveling to affected areas, because non-native people tend to develop more severe illness when infected. Protection begins by the 10th day after vaccine administration in 95% of people, and had been reported to last for at least 10 years. The World Health Organization (WHO) now states that a single dose of vaccine is sufficient to confer lifelong immunity against yellow fever disease. The attenuated live vaccine stem 17D

11446-476: The university before course registration. Some schools' core requirements differ (e.g., students in the School of Science and Engineering are required to take fewer language classes than students in the School of Liberal Arts). Tulane was elected to the Association of American Universities in 1958. It is classified among "R1: Doctoral Universities – Very high research activity" and had research expenditure of $ 193.3 million in fiscal year 2018. In 2008, Tulane

11564-521: The university initiated an extensive university-wide core curriculum. Several major elements of the university core include freshman seminars called TIDES classes, a two-tier writing course sequence, and a two-tier course sequence for public service. Many other course requirements of the core curriculum can be certified through Advanced Placement (AP) or International Baccalaureate (IB) exam scores, or placement exams in English and foreign languages offered by

11682-760: The university president. In 2008, Tulane became one of 76 U.S. colleges and the only Louisiana college to maintain an endowment above $ 1 billion. Tulane is organized into 10 schools centered around liberal arts, sciences, and specialized professions. All undergraduate students are enrolled in the Newcomb-Tulane College . The graduate programs are governed by the individual schools. Newcomb-Tulane College serves as an administrative center for all aspects of undergraduate life at Tulane, while individual schools direct specific courses of study. The first architecture courses at Tulane leading to an architectural engineering degree were offered in 1894. After beginning as part of

11800-477: The university's total endowment to more than $ 1.1 billion; by March 2009, Yvette Jones, Tulane's Chief Operating Officer, told Tulane's Staff Advisory Council that the endowment "has lost close to 37%", affected by the Great Recession . In 2021, Tulane had to evacuate all students and close down for a month due to damage from Hurricane Ida . No classes took place for two weeks, then there were virtual classes for

11918-428: The upbuilding of the best commercial and friendly relations between these Trans-Caribbean peoples and the United States." University College was established in 1942 as Tulane's division of continuing education. By 1950, the School of Architecture had grown out of Engineering into an independent school. In 1958, the university was elected to the Association of American Universities , an organization consisting of 62 of

12036-516: The urban cycle, both in Africa and South America, a sylvatic cycle (forest or jungle cycle) is present, where Aedes africanus (in Africa) or mosquitoes of the genus Haemagogus and Sabethes (in South America) serve as vectors. In the jungle, the mosquitoes infect mainly nonhuman primates; the disease is mostly asymptomatic in African primates. In South America, the sylvatic cycle is currently

12154-587: The vector A. aegypti . Five genotypes (Angola, Central/East Africa, East Africa, West Africa I, and West Africa II) occur only in Africa. West Africa genotype I is found in Nigeria and the surrounding region. West Africa genotype I appears to be especially infectious, as it is often associated with major outbreaks. The three genotypes found outside of Nigeria and Angola occur in areas where outbreaks are rare. Two outbreaks, in Kenya (1992–1993) and Sudan (2003 and 2005), involved

12272-587: The virus is transmitted from mosquitoes to humans or other primates. In the "urban cycle", only the yellow fever mosquito A. aegypti is involved. It is well adapted to urban areas, and can also transmit other diseases, including Zika fever , dengue fever , and chikungunya . The urban cycle is responsible for the major outbreaks of yellow fever that occur in Africa. Except for an outbreak in Bolivia in 1999, this urban cycle no longer exists in South America. Besides

12390-423: The world. In 1927, yellow fever virus became the first human virus to be isolated. Yellow fever begins after an incubation period of three to six days. Most cases cause only mild infection with fever, headache, chills, back pain, fatigue, loss of appetite, muscle pain, nausea, and vomiting. In these cases, the infection lasts only three to six days. But in 15% of cases, people enter a second, toxic phase of

12508-461: The wound, and the virus reaches the bloodstream of the bitten person. Transovarial transmissionial and transstadial transmission of yellow fever virus within A. aegypti , that is, the transmission from a female mosquito to its eggs and then larvae, are indicated. This infection of vectors without a previous blood meal seems to play a role in single, sudden breakouts of the disease. Three epidemiologically different infectious cycles occur in which

12626-487: Was about 5 × 10  substitutions/site/year, similar to that of other RNA viruses. The main vector ( A. aegypti ) also occurs in tropical and subtropical regions of Asia, the Pacific, and Australia, but yellow fever had never occurred there until jet travel introduced 11 cases from the 2016 Angola and DR Congo yellow fever outbreak in Africa. Proposed explanations include: But none is considered satisfactory. Another proposal

12744-640: Was broken on Tulane's Yulman Stadium between Reily Recreation Center and Turchin Stadium. Tulane Green Wave football had played in the Mercedes-Benz Superdome since Tulane Stadium 's demolition in 1980. They now play in Yulman Stadium , which opened in September 2014. After Hurricane Katrina , Tulane has continued to build new facilities and renovate old spaces on its campus. The newest dorm buildings, Lake and River Residence Halls, were completed in 2023 following

12862-400: Was designed by New York architect James Gamble Rogers , noted for his work with Yale University 's campus. The Newcomb campus is home to Tulane's performing and fine arts venues. The back of campus, between Willow Street and South Claiborne, is home to two residence halls (Aron Residences and Décou-Labat Residences), Reily Recreation Center, and Turchin Stadium , and in January 2013, ground

12980-411: Was developed in 1937 by Max Theiler . The WHO recommends routine vaccination for people living in affected areas between the 9th and 12th month after birth. Up to one in four people experience fever, aches, and local soreness and redness at the site of injection. In rare cases (less than one in 200,000 to 300,000), the vaccination can cause yellow fever vaccine-associated viscerotropic disease, which

13098-407: Was endemic in Africa, local populations had developed some immunity to it. When an outbreak of yellow fever would occur in an African community where colonists resided, most Europeans died, while the indigenous Africans usually developed nonlethal symptoms resembling influenza . This phenomenon, in which certain populations develop immunity to yellow fever due to prolonged exposure in their childhood,

13216-580: Was established in 2005. In 1914 the Southern School of Social Sciences and Public Services was the first training program for social workers in the Deep South . By 1927 the school became a separate program with a two-year Master of Arts. The Tulane University School of Social Work has awarded the master of social work degrees to more than 4,700 students from all 50 of the United States and more than 30 other countries. Tulane offers continuing education courses and associate's and bachelor's degrees through

13334-457: Was founded in 1834 and is the 15th oldest medical school in the United States. Faculty have been noted for innovation. For example, in 1850 J. Lawrence Smith invented the inverted microscope . In the following year John Leonard Riddell invented the first practical microscope to allow binocular viewing through a single objective lens. In 2001 the Tulane Center for Gene Therapy started as

13452-626: Was held in New Orleans with the Southeastern Library Association . The first Black president of LLA was Idella Washington who was elected in 1998. In 1999 the LLA Bulletin was renamed Louisiana Libraries. The 2021 conference was held as a virtual conference during the COVID-19 pandemic. The Louisiana Library Association established its Awards program in 1944. The LLA offers multiple scholarships each year. The LLA Scholarship

13570-485: Was published by Dyer. In July 2004, Tulane received two $ 30 million donations to its endowment , the largest individual or combined gifts in the university's history. The donations came from James H. Clark , a member of the university's board of trustees and founder of Netscape , and David Filo , a graduate of its School of Engineering and co-founder of Yahoo! . A fund-raising campaign called "Promise & Distinction" raised $ 730.6 million by October 3, 2008, increasing

13688-537: Was ranked by the Ford Foundation as the major international studies research institution in the South and one of the top 15 nationally. The National Institutes of Health ranks funding to Tulane at 79th. The university is home to various research centers, including the Amistad Research Center . Overall university rankings and ratings include: According to U.S. News & World Report Tulane

13806-648: Was reorganized in 1925. The LLA Convention or Conference began in 1909 has been held annually (except for 1914-1924, 1933, and 1945). LLA became a chapter member of the American Library Association in 1939, and has been a member since then with the exception of a period from March 5, 1963 through mid-1965 when the Executive Board of LLA resigned from ALA because the organization was not integrated. LLA had voted in 1947 to admit Black members, but because of state segregation laws had not been able to implement

13924-657: Was supported by the GAVI alliance and governmental organizations in Europe and Africa. According to the WHO, mass vaccination cannot eliminate yellow fever because of the vast number of infected mosquitoes in urban areas of the target countries, but it will significantly reduce the number of people infected. Demand for yellow fever vaccine has continued to increase due to the growing number of countries implementing yellow fever vaccination as part of their routine immunization programmes. Recent upsurges in yellow fever outbreaks in Angola (2015),

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