122-520: The Tale of Johnny Town-Mouse is a children's book written and illustrated by Beatrix Potter and first published by Frederick Warne & Co . In December 1918 . The tale is based on the Aesop fable , " The Town Mouse and the Country Mouse ", with details taken from Horace's Satires 2.6.79-117 . It tells of a country mouse and a city mouse who visit each other in their respective homes. After sampling
244-482: A barrister in London. Rupert practiced law, specialising in equity law and conveyancing . He married Helen Leech (1839–1932) on 8 August 1863 at Hyde Unitarian Chapel, Gee Cross . Helen was the daughter of Jane Ashton (1806–1884) and John Leech, a wealthy cotton merchant and shipbuilder from Stalybridge . Helen's first cousins were siblings Harriet Lupton ( née Ashton) and Thomas Ashton, 1st Baron Ashton of Hyde . It
366-725: A decreased level of consciousness . Bacterial and viral cases of pneumonia usually result in similar symptoms. Some causes are associated with classic, but non-specific, clinical characteristics. Pneumonia caused by Legionella may occur with abdominal pain, diarrhea , or confusion. Pneumonia caused by Streptococcus pneumoniae is associated with rusty colored sputum. Pneumonia caused by Klebsiella may have bloody sputum often described as "currant jelly". Bloody sputum (known as hemoptysis ) may also occur with tuberculosis , Gram-negative pneumonia, lung abscesses and more commonly acute bronchitis . Pneumonia caused by Mycoplasma pneumoniae may occur in association with swelling of
488-516: A leading cause of death in developing countries, and also among the very old, the very young, and the chronically ill. Pneumonia often shortens the period of suffering among those already close to death and has thus been called "the old man's friend". People with infectious pneumonia often have a productive cough , fever accompanied by shaking chills , shortness of breath , sharp or stabbing chest pain during deep breaths, and an increased rate of breathing . In elderly people, confusion may be
610-401: A stethoscope or increased respiratory rate. Grunting and nasal flaring may be other useful signs in children less than five years old. Lack of wheezing is an indicator of Mycoplasma pneumoniae in children with pneumonia, but as an indicator it is not accurate enough to decide whether or not macrolide treatment should be used. The presence of chest pain in children with pneumonia doubles
732-704: A 70-years-after-death limit. Hill Top Farm was opened to the public by the National Trust in 1946; her artwork was displayed there until 1985 when it was moved to William Heelis's former law offices in Hawkshead , also owned by the National Trust as the Beatrix Potter Gallery . Potter gave her folios of mycological drawings to the Armitt Library and Museum in Ambleside before her death. The Tale of Peter Rabbit
854-628: A Victorian Genius (2008). In 1971, a ballet film was released, The Tales of Beatrix Potter , directed by Reginald Mills, set to music by John Lanchbery with choreography by Frederick Ashton , and performed in character costume by members of the Royal Ballet and the Royal Opera House orchestra. The ballet of the same name has been performed by other dance companies around the world. In 1992, Potter's children's book The Tale of Benjamin Bunny
976-582: A book. In 1997, the Linnean Society issued a posthumous apology to Potter for the sexism displayed in its handling of her research. Potter's artistic and literary interests were deeply influenced by fairy tales and fantasy. She was a student of the classic fairy tales of Western Europe as well as stories from the Old Testament , John Bunyan 's The Pilgrim's Progress and Harriet Beecher Stowe 's Uncle Tom's Cabin . She grew up with Aesop's Fables ,
1098-418: A chest radiograph is recommended. Findings do not always match the severity of disease and do not reliably separate between bacterial and viral infection. X-ray presentations of pneumonia may be classified as lobar pneumonia , bronchopneumonia , lobular pneumonia , and interstitial pneumonia . Bacterial, community-acquired pneumonia classically show lung consolidation of one lung segmental lobe , which
1220-493: A cough of longer duration, and pulmonary emboli present with acute onset sharp chest pain and shortness of breath. Mild pneumonia should be differentiated from upper respiratory tract infection (URTI). Severe pneumonia should be differentiated from acute heart failure . Pulmonary infiltrates that resolved after giving mechanical ventilation should point to heart failure and atelectasis rather than pneumonia. For recurrent pneumonia, underlying lung cancer, metastasis , tuberculosis,
1342-479: A cough or difficulty breathing and a rapid respiratory rate, chest indrawing, or a decreased level of consciousness. A rapid respiratory rate is defined as greater than 60 breaths per minute in children under 2 months old, greater than 50 breaths per minute in children 2 months to 1 year old, or greater than 40 breaths per minute in children 1 to 5 years old. In children, low oxygen levels and lower chest indrawing are more sensitive than hearing chest crackles with
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#17328770575061464-415: A day or two before other signs. Examination of the chest may be normal, but it may show decreased expansion on the affected side. Harsh breath sounds from the larger airways that are transmitted through the inflamed lung are termed bronchial breathing and are heard on auscultation with a stethoscope. Crackles (rales) may be heard over the affected area during inspiration . Percussion may be dulled over
1586-800: A foreign bodies, immunosuppression, and hypersensitivity should be suspected. Prevention includes vaccination , environmental measures, and appropriate treatment of other health problems. It is believed that, if appropriate preventive measures were instituted globally, mortality among children could be reduced by 400,000; and, if proper treatment were universally available, childhood deaths could be decreased by another 600,000. Vaccination prevents against certain bacterial and viral pneumonias both in children and adults. Influenza vaccines are modestly effective at preventing symptoms of influenza, The Centers for Disease Control and Prevention (CDC) recommends yearly influenza vaccination for every person 6 months and older. Immunizing health care workers decreases
1708-400: A higher dose of radiation, and cannot be done at bedside. Lung ultrasound may also be useful in helping to make the diagnosis. Ultrasound is radiation free and can be done at bedside. However, ultrasound requires specific skills to operate the machine and interpret the findings. It may be more accurate than chest X-ray. In people managed in the community, determining the causative agent
1830-462: A history of smoking, a poor ability to cough (such as following a stroke), and a weak immune system . Vaccines to prevent certain types of pneumonia (such as those caused by Streptococcus pneumoniae bacteria, linked to influenza , or linked to COVID-19 ) are available. Other methods of prevention include hand washing to prevent infection, and not smoking. Treatment depends on the underlying cause. Pneumonia believed to be due to bacteria
1952-813: A more independent process of reproduction. Rebuffed by William Thiselton-Dyer , the Director at Kew, because of her sex and amateur status, Potter wrote up her conclusions and submitted a paper, On the Germination of the Spores of the Agaricineae , to the Linnean Society in 1897. It was introduced by Massee because, as a woman, Potter could not attend proceedings nor read her paper. She subsequently withdrew it, realising that some of her samples were contaminated, but continued her microscopic studies for several more years. Her work
2074-534: A nursing trust for local villages and served on various committees and councils responsible for footpaths and other rural issues. Soon after acquiring Hill Top Farm, Potter became keenly interested in the breeding and raising of Herdwick sheep , the indigenous fell sheep. In 1923 she bought a large sheep farm in the Troutbeck Valley called Troutbeck Park Farm , formerly a deer park, restoring its land with thousands of Herdwick sheep. This established her as one of
2196-665: A pioneer of character merchandising. In 1903, Peter Rabbit was the first fictional character to be made into a patented stuffed toy , making him the oldest licensed character . Born into an upper-middle-class household, Potter was educated by governesses and grew up isolated from other children. She had numerous pets and spent holidays in Scotland and the Lake District , developing a love of landscape, flora and fauna, all of which she closely observed and painted. Potter's study and watercolours of fungi led to her being widely respected in
2318-475: A pleasant intelligent race, but I should think awkward to live with... the language is past description." Potter had been a disciple of the land conservation and preservation ideals of her long-time friend and mentor, Canon Hardwicke Rawnsley , the first secretary and founding member of the National Trust . According to the National Trust, "she supported the efforts of the National Trust to preserve not just
2440-514: A revered naturalist and amateur mycologist, during a summer holiday in Dunkeld in Perthshire in 1892. He helped improve the accuracy of her illustrations, taught her taxonomy , and supplied her with live specimens to paint during the winter. Curious as to how fungi reproduced, Potter began microscopic drawings of fungus spores (the agarics ) and in 1895 developed a theory of their germination . Through
2562-568: A village in the Lake District. Over the following decades, she purchased additional farms to preserve the unique hill country landscape. In 1913, at the age of 47, she married William Heelis (1871–1945), a respected local solicitor with an office in Hawkshead . Potter was also a prize-winning breeder of Herdwick sheep and a prosperous farmer keenly interested in land preservation. She continued to write, illustrate, and design merchandise based on her children's books for British publisher Warne until
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#17328770575062684-456: A way to earn money in the 1890s, Potter printed Christmas cards of her own design, as well as cards for special occasions. These were her first commercially successful works as an illustrator. Mice and rabbits were the most frequent subject of her fantasy paintings. In 1890, the firm of Hildesheimer and Faulkner bought several of the drawings of her rabbit Benjamin Bunny to illustrate verses by Frederic Weatherly titled A Happy Pair . In 1893,
2806-493: Is an invaluable source for understanding a vibrant part of British society in the late 19th century. It describes Potter's maturing artistic and intellectual interests, her often amusing insights into the places she visited, and her unusual ability to observe nature and to describe it. Started in 1881, her journal ends in 1897 when her artistic and intellectual energies were absorbed in scientific study and in efforts to publish her drawings. Precocious but reserved and often bored, she
2928-411: Is another rare cause due to lipids entering the lung. These lipids can either be inhaled or spread to the lungs from elsewhere in the body. Pneumonia frequently starts as an upper respiratory tract infection that moves into the lower respiratory tract. It is a type of pneumonitis (lung inflammation). The normal flora of the upper airway give protection by competing with pathogens for nutrients. In
3050-996: Is associated with Chlamydia psittaci ; farm animals with Coxiella burnetti ; aspiration of stomach contents with anaerobic organisms; and cystic fibrosis with Pseudomonas aeruginosa and Staphylococcus aureus . Streptococcus pneumoniae is more common in the winter, and it should be suspected in persons aspirating a large number of anaerobic organisms. In adults, viruses account for about one third of pneumonia cases, and in children for about 15% of them. Commonly implicated agents include rhinoviruses , coronaviruses , influenza virus , respiratory syncytial virus (RSV), adenovirus , and parainfluenza . Herpes simplex virus rarely causes pneumonia, except in groups such as newborns, persons with cancer, transplant recipients, and people with significant burns. After organ transplantation or in otherwise immunocompromised persons, there are high rates of cytomegalovirus pneumonia. Those with viral infections may be secondarily infected with
3172-448: Is associated with an increased risk of pneumonia. Approximately 10% of people who require mechanical ventilation develop ventilator-associated pneumonia , and people with a gastric feeding tube have an increased risk of developing aspiration pneumonia . Moreover, the misplacement of a feeding tube can lead to aspiration pneumonia. 28% of tube malposition results in pneumonia. As with Avanos Medical 's feeding tube placement system,
3294-506: Is available for adults, and has been found to decrease the risk of invasive pneumococcal disease by 74%, but there is insufficient evidence to suggest using the pneumococcal vaccine to prevent pneumonia or death in the general adult population. The CDC recommends that young children and adults over the age of 65 receive the pneumococcal vaccine, as well as older children or younger adults who have an increased risk of getting pneumococcal disease. The pneumococcal vaccine has been shown to reduce
3416-644: Is due primarily to cytokine -induced systemic inflammation . In the developed world , these infections are most common in people returning from travel or in immigrants. Around the world, parasitic pneumonia is most common in the immunodeficient. Idiopathic interstitial pneumonia or noninfectious pneumonia is a class of diffuse lung diseases . They include diffuse alveolar damage , organizing pneumonia , nonspecific interstitial pneumonia , lymphocytic interstitial pneumonia , desquamative interstitial pneumonia , respiratory bronchiolitis interstitial lung disease , and usual interstitial pneumonia . Lipoid pneumonia
3538-796: Is due to infections caused primarily by bacteria or viruses and less commonly by fungi and parasites . Although more than 100 strains of infectious agents have been identified, only a few are responsible for the majority of cases. Mixed infections with both viruses and bacteria may occur in roughly 45% of infections in children and 15% of infections in adults. A causative agent may not be isolated in about half of cases despite careful testing. In an active population-based surveillance for community-acquired pneumonia requiring hospitalization in five hospitals in Chicago and Nashville from January 2010 through June 2012, 2259 patients were identified who had radiographic evidence of pneumonia and specimens that could be tested for
3660-460: Is important to treatment, as it correlates to which pathogens are likely suspects, which mechanisms are likely, which antibiotics are likely to work or fail, and which complications can be expected based on the person's health status. Community-acquired pneumonia (CAP) is acquired in the community, outside of health care facilities. Compared with healthcare-associated pneumonia, it is less likely to involve multidrug-resistant bacteria. Although
3782-445: Is increased. Bacteria are the most common cause of community-acquired pneumonia (CAP), with Streptococcus pneumoniae isolated in nearly 50% of cases. Other commonly isolated bacteria include Haemophilus influenzae in 20%, Chlamydophila pneumoniae in 13%, and Mycoplasma pneumoniae in 3% of cases; Staphylococcus aureus ; Moraxella catarrhalis ; and Legionella pneumophila . A number of drug-resistant versions of
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3904-448: Is known as lobar pneumonia. However, findings may vary, and other patterns are common in other types of pneumonia. Aspiration pneumonia may present with bilateral opacities primarily in the bases of the lungs and on the right side. Radiographs of viral pneumonia may appear normal, appear hyper-inflated, have bilateral patchy areas, or present similar to bacterial pneumonia with lobar consolidation. Radiologic findings may not be present in
4026-576: Is most common in the Southwestern United States. The number of cases of fungal pneumonia has been increasing in the latter half of the 20th century due to increasing travel and rates of immunosuppression in the population. For people infected with HIV/AIDS , PCP is a common opportunistic infection . A variety of parasites can affect the lungs, including Toxoplasma gondii , Strongyloides stercoralis , Ascaris lumbricoides , and Plasmodium malariae . These organisms typically enter
4148-530: Is not cost-effective and typically does not alter management. For people who do not respond to treatment, sputum culture should be considered, and culture for Mycobacterium tuberculosis should be carried out in persons with a chronic productive cough. Microbiological evaluation is also indicated in severe pneumonia, alcoholism, asplenia , immunosuppression, HIV infection, and those being empirically treated for MRSA of pseudomonas. Although positive blood culture and pleural fluid culture definitively establish
4270-781: Is only now being properly evaluated. Potter later gave her other mycological and scientific drawings to the Armitt Museum and Library in Ambleside, where mycologists still refer to them to identify fungi. There is also a collection of her fungus paintings at the Perth Museum and Art Gallery in Perth, Scotland, donated by Charles McIntosh. In 1967, the mycologist W. P. K. Findlay included many of Potter's beautifully accurate fungus drawings in his Wayside & Woodland Fungi , thereby fulfilling her desire to one day have her fungus drawings published in
4392-604: Is owned by Warne , The Tailor of Gloucester by the Tate Gallery , and The Tale of the Flopsy Bunnies by the British Museum . Beatrix Potter was the first to recognise that content—as we now call the stuff that makes up a book or a film—was only the beginning. In 1903, Peter hopped outside his pages to become a patented soft toy, which gave him the distinction of being not only Mr. McGregor‘s mortal enemy, but also becoming
4514-465: Is sometimes called MCAP (medical care–associated pneumonia). People may become infected with pneumonia in a hospital; this is defined as pneumonia not present at the time of admission (symptoms must start at least 48 hours after admission). It is likely to involve hospital-acquired infections , with higher risk of multidrug-resistant pathogens. People in a hospital often have other medical conditions, which may make them more susceptible to pathogens in
4636-723: Is sometimes more broadly applied to any condition resulting in inflammation of the lungs (caused for example by autoimmune diseases , chemical burns or drug reactions); however, this inflammation is more accurately referred to as pneumonitis . Factors that predispose to pneumonia include smoking, immunodeficiency , alcoholism, chronic obstructive pulmonary disease , sickle cell disease (SCD), asthma , chronic kidney disease , liver disease , and biological aging . Additional risks in children include not being breastfed , exposure to cigarette smoke and other air pollution, malnutrition, and poverty. The use of acid-suppressing medications – such as proton-pump inhibitors or H2 blockers –
4758-432: Is treated with antibiotics . If the pneumonia is severe, the affected person is generally hospitalized. Oxygen therapy may be used if oxygen levels are low. Each year, pneumonia affects about 450 million people globally (7% of the population) and results in about 4 million deaths. With the introduction of antibiotics and vaccines in the 20th century, survival has greatly improved. Nevertheless, pneumonia remains
4880-490: Is uncommon, but occurs more commonly in individuals with weakened immune systems due to AIDS, immunosuppressive drugs , or other medical problems. It is most often caused by Histoplasma capsulatum , Blastomyces , Cryptococcus neoformans , Pneumocystis jiroveci ( pneumocystis pneumonia , or PCP), and Coccidioides immitis . Histoplasmosis is most common in the Mississippi River basin , and coccidioidomycosis
5002-563: Is worth $ 500 million today. In the process, she created a system that continues to benefit all licensed characters, from Mickey Mouse to Harry Potter." The largest public collection of her letters and drawings is the Leslie Linder Bequest and Leslie Linder Collection at the Victoria and Albert Museum in London. (Linder was the collector who—after five years of work—finally transcribed Potter's early journal, originally written in code.) In
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5124-645: The cat frightening and the food strange, he returns by the hamper. Sometime later, Johnny Town-Mouse pays him a visit, but finding such things as cows and lawnmowers frightening, returns to the city himself. An animated adaptation of the story, shown alongside The Tale of Two Bad Mice , was featured on The World of Peter Rabbit and Friends in 1995 with Johnny Town-Mouse voiced by British actor Hugh Laurie . Beatrix Potter Helen Beatrix Heelis ( née Potter ; 28 July 1866 – 22 December 1943), usually known as Beatrix Potter ( / ˈ b iː ə t r ɪ k s / BEE -ə-triks ),
5246-465: The 150th anniversary of Beatrix Potter's birth by showing that she was "far more than a 19th-century weekend painter. She was an artist of astonishing range." In December 2017, the asteroid 13975 Beatrixpotter , discovered by Belgian astronomer Eric Elst in 1992, was renamed in her memory. In 2022, an exhibition, Beatrix Potter: Drawn to Nature , was held at the Victoria and Albert Museum. Research for
5368-578: The 20 acres (8.1 ha) Castle Farm across the road from Hill Top Farm. She visited Hill Top at every opportunity, and her books written during this period (such as The Tale of Ginger and Pickles , about the local shop in Near Sawrey and The Tale of Mrs. Tittlemouse , a wood mouse) reflect her increasing participation in village life and her delight in country living. "Hill Top is to be presented to my visitors as if I had just gone out and they had just missed me." —Statement by Potter in her will to
5490-630: The CORTRAK* 2 EAS, which was recalled in May 2022 by the FDA due to adverse events reported, including pneumonia, caused a total of 60 injuries and 23 patient deaths, as communicated by the FDA. For people with certain variants of the FER gene , the risk of death is reduced in sepsis caused by pneumonia. However, for those with TLR6 variants, the risk of getting Legionnaires' disease
5612-644: The National Trust, including over 4,000 acres (16 km ) of land, sixteen farms, cottages and herds of cattle and Herdwick sheep. Hers was the largest gift at that time to the National Trust, and it enabled the preservation of the land now included in the Lake District National Park and the continuation of fell farming. The central office of the National Trust in Swindon was named "Heelis" in 2005 in her memory. William Heelis continued his stewardship of their properties and of her literary and artistic work for
5734-560: The National Trust. Owning and managing these working farms required routine collaboration with the widely respected William Heelis. By the summer of 1912, Heelis had proposed marriage and Potter had accepted; although she did not immediately tell her parents, who once again disapproved because Heelis was only a country solicitor. Potter and Heelis were married on 15 October 1913 in London at St Mary Abbots in Kensington . The couple moved immediately to Near Sawrey , residing at Castle Cottage,
5856-451: The Trust for seven years until the National Trust could afford to repurchase most of the property from her. Potter's stewardship of these farms earned her full regard, but she was not without her critics, not the least of which were her contemporaries who felt she used her wealth and the position of her husband to acquire properties in advance of their being made public. She was notable in observing
5978-785: The United States, the largest public collections are those in the Rare Book Department of the Free Library of Philadelphia , and the Cotsen Children's Library at Princeton University . In 2015, a manuscript for an unpublished book was discovered by Jo Hanks, a publisher at Penguin Random House Children's Books, in the Victoria and Albert Museum archive. The book The Tale of Kitty-in-Boots , with illustrations by Quentin Blake ,
6100-513: The above infections are becoming more common, including drug-resistant Streptococcus pneumoniae (DRSP) and methicillin-resistant Staphylococcus aureus (MRSA). The spreading of organisms is facilitated by certain risk factors. Alcoholism is associated with Streptococcus pneumoniae , anaerobic organisms , and Mycobacterium tuberculosis ; smoking facilitates the effects of Streptococcus pneumoniae , Haemophilus influenzae , Moraxella catarrhalis , and Legionella pneumophila . Exposure to birds
6222-560: The additional feature of pulmonary consolidation . Pneumonia is most commonly classified by where or how it was acquired: community-acquired, aspiration, healthcare-associated , hospital-acquired , and ventilator-associated pneumonia. It may also be classified by the area of the lung affected: lobar, bronchial pneumonia and acute interstitial pneumonia ; or by the causative organism. Pneumonia in children may additionally be classified based on signs and symptoms as non-severe, severe, or very severe. The setting in which pneumonia develops
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#17328770575066344-421: The affected lung, and increased, rather than decreased, vocal resonance distinguishes pneumonia from a pleural effusion . A chest radiograph is frequently used in diagnosis. In people with mild disease, imaging is needed only in those with potential complications, those not having improved with treatment, or those in which the cause is uncertain. If a person is sufficiently sick to require hospitalization,
6466-421: The alveoli, resulting in the consolidation seen on chest X-ray. Viruses may reach the lung by a number of different routes. Respiratory syncytial virus is typically contracted when people touch contaminated objects and then touch their eyes or nose. Other viral infections occur when contaminated airborne droplets are inhaled through the nose or mouth. Once in the upper airway, the viruses may make their way into
6588-517: The bacteria Streptococcus pneumoniae , Staphylococcus aureus , or Haemophilus influenzae , particularly when other health problems are present. Different viruses predominate at different times of the year; during flu season , for example, influenza may account for more than half of all viral cases. Outbreaks of other viruses also occur occasionally, including hantaviruses and coronaviruses. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can also result in pneumonia. Fungal pneumonia
6710-450: The basis of Potter's future career as a writer-artist-storyteller. In 1900, Potter revised her tale about the four little rabbits, and fashioned a dummy book of it – it has been suggested, in imitation of Helen Bannerman 's 1899 bestseller The Story of Little Black Sambo . Unable to find a buyer for the work, she published it for family and friends at her own expense in December 1901. It
6832-449: The blood. Once in the lungs, bacteria may invade the spaces between cells and between alveoli, where the macrophages and neutrophils (defensive white blood cells ) attempt to inactivate the bacteria. The neutrophils also release cytokines, causing a general activation of the immune system. This leads to the fever, chills, and fatigue common in bacterial pneumonia. The neutrophils, bacteria, and fluid from surrounding blood vessels fill
6954-511: The body through direct contact with the skin, ingestion, or via an insect vector. Except for Paragonimus westermani , most parasites do not specifically affect the lungs but involve the lungs secondarily to other sites. Some parasites, in particular those belonging to the Ascaris and Strongyloides genera, stimulate a strong eosinophilic reaction, which may result in eosinophilic pneumonia . In other infections, such as malaria, lung involvement
7076-546: The cause and support decisions about who should receive antibiotics. Antibiotics are encouraged if the procalcitonin level reaches 0.25 μg/L, strongly encouraged if it reaches 0.5 μg/L, and strongly discouraged if the level is below 0.10 μg/L. In people requiring hospitalization, pulse oximetry , chest radiography and blood tests – including a complete blood count , serum electrolytes , C-reactive protein level, and possibly liver function tests – are recommended. The diagnosis of influenza-like illness can be made based on
7198-466: The children of her former governess Annie Carter Moore, particularly to Moore's eldest son Noel, who was often ill. In September 1893, Potter was on holiday at Eastwood in Dunkeld , Perthshire. She had run out of things to say to Noel, and so she told him a story about "four little rabbits whose names were Flopsy, Mopsy, Cottontail, and Peter". It became one of the most famous children's letters ever written and
7320-427: The condition, but they are associated with side effects. Zanamivir or oseltamivir decrease the chance that people who are exposed to the virus will develop symptoms; however, it is recommended that potential side effects are taken into account. Smoking cessation and reducing indoor air pollution , such as that from cooking indoors with wood, crop residues or dung , are both recommended. Smoking appears to be
7442-515: The connections of her uncle Sir Henry Enfield Roscoe , a chemist and vice-chancellor of the University of London , she consulted with botanists at Kew Gardens , convincing George Massee of her ability to germinate spores and her theory of hybridisation . She did not believe in the theory of symbiosis proposed by Simon Schwendener , the German mycologist, as previously thought; instead, she proposed
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#17328770575067564-452: The country, and both children became adept students of natural history . In 1882, when Dalguise was no longer available, the Potters took their first summer holiday in the Lake District , at Wray Castle near Lake Windermere . Here Potter met Hardwicke Rawnsley , vicar of Wray and later the founding secretary of the National Trust , whose interest in the countryside and country life inspired
7686-437: The countryside. As children, Potter and Bertram had numerous small animals as pets which they observed closely and drew endlessly. In their schoolroom, Potter and Bertram kept a variety of small pets—mice, rabbits, a hedgehog and some bats, along with collections of butterflies and other insects—which they drew and studied. Potter was devoted to the care of her small animals, often taking them with her on long holidays. In most of
7808-404: The diagnosis is unlikely. However, the underlying cause can be difficult to confirm, as there is no definitive test able to distinguish between bacterial and non-bacterial cause. The overall impression of a physician appears to be at least as good as decision rules for making or excluding the diagnosis. The World Health Organization has defined pneumonia in children clinically based on either
7930-508: The diagnosis of the type of micro-organism involved, a positive sputum culture has to be interpreted with care for the possibility of colonisation of respiratory tract. Testing for other specific organisms may be recommended during outbreaks, for public health reasons. In those hospitalized for severe disease, both sputum and blood cultures are recommended, as well as testing the urine for antigens to Legionella and Streptococcus . Viral infections, can be confirmed via detection of either
8052-409: The duties of land management and her diminishing eyesight made it difficult to continue. Potter died of pneumonia and heart disease on 22 December 1943 at her home in Near Sawrey at the age of 77, leaving almost all her property to the National Trust . She is credited with preserving much of the land that now constitutes the Lake District National Park . Potter's books continue to sell throughout
8174-758: The early stages of the disease, especially in the presence of dehydration, or may be difficult to interpret in the obese or those with a history of lung disease. Complications such as pleural effusion may also be found on chest radiographs. Laterolateral chest radiographs can increase the diagnostic accuracy of lung consolidation and pleural effusion. A CT scan can give additional information in indeterminate cases and provide more details in those with an unclear chest radiograph (for example occult pneumonia in chronic obstructive pulmonary disease). They can be used to exclude pulmonary embolism and fungal pneumonia , and detect lung abscesses in those who are not responding to treatments. However, CT scans are more expensive, have
8296-524: The exhibition identified the man's court waistcoat c. 1780s, which inspired Potter's sketch in The Tailor of Gloucester . There are many interpretations of Potter's literary work, the sources of her art, and her life and times. These include critical evaluations of her corpus of children's literature and Modernist interpretations of Humphrey Carpenter and Katherine Chandler. Judy Taylor, That Naughty Rabbit: Beatrix Potter and Peter Rabbit (rev. 2002) tells
8418-712: The fairy tales of the Brothers Grimm and Hans Christian Andersen , Charles Kingsley 's The Water Babies , the folk tales and mythology of Scotland , the German Romantics , Shakespeare , and the romances of Sir Walter Scott . As a young child, before the age of eight, Edward Lear 's A Book of Nonsense , including the much-loved The Owl and the Pussycat , and Lewis Carroll 's Alice in Wonderland had made their impression, although she later said of Alice that she
8540-431: The farm for her while she made physical improvements and learned the techniques of fell farming and of raising livestock, including pigs, cows and chickens; the following year she added sheep. Realising she needed to protect her boundaries, she sought advice from W.H. Heelis & Son, a local firm of solicitors with offices in nearby Hawkshead . With William Heelis acting for her, she bought contiguous pasture, and in 1909
8662-478: The field of mycology . In her thirties, Potter self-published the highly successful children's book The Tale of Peter Rabbit . Following this, Potter began writing and illustrating children's books full-time. Potter wrote over sixty books, with the best known being her twenty-three children's tales . In 1905, using the proceeds from her books and a legacy from an aunt, Potter bought Hill Top Farm in Near Sawrey ,
8784-487: The first fifteen years of her life, Potter spent summer holidays at Dalguise , an estate on the River Tay in Perthshire, Scotland . There she sketched and explored an area that nourished her imagination and her observation. Her first sketchbook from those holidays, kept at age 8 and dated 1875, is held at and has been digitised by the Victoria & Albert Museum, London . Potter and her brother were allowed great freedom in
8906-666: The first licensed character. In 1903, Potter created the first Peter Rabbit soft toy and registered him at the Patent Office in London, making Peter the oldest licensed fictional character. Merchandise of Peter and other Potter characters have been sold at Harrods department store in London since at least 1910 when the range first appeared in their catalogues. Along with her writing Potter would continue to oversee merchandising and licensing opportunities for her characters. On her legacy, Nicholas Tucker in The Guardian writes, "she
9028-634: The hospital. Ventilator-associated pneumonia occurs in people breathing with the help of mechanical ventilation. Ventilator-associated pneumonia is specifically defined as pneumonia that arises more than 48 to 72 hours after endotracheal intubation . Several diseases can present with similar signs and symptoms to pneumonia, such as: chronic obstructive pulmonary disease, asthma, pulmonary edema , bronchiectasis , lung cancer, and pulmonary emboli . Unlike pneumonia, asthma and COPD typically present with wheezing, pulmonary edema presents with an abnormal electrocardiogram , cancer and bronchiectasis present with
9150-547: The last an illustrator whose work was later collected by her father, was a great influence. Her earliest illustrations focused on traditional rhymes and stories like Cinderella , Sleeping Beauty , Ali Baba and the Forty Thieves , Puss in Boots , and Little Red Riding Hood . However, most often her illustrations were fantasies featuring her own pets: mice, rabbits, kittens, and guinea pigs. In her teenage years, Potter
9272-562: The last of whom was Annie Moore ( née Carter), just three years older than Potter, who tutored Potter in German as well as acting as lady's companion . She and Potter remained friends throughout their lives, and Annie's eight children were the recipients of many of Potter's picture letters. It was Annie who later suggested that these letters might make good children's books. She and her younger brother Walter Bertram (1872–1918) grew up with few friends outside their large extended family. Her parents were artistic, interested in nature, and enjoyed
9394-582: The latter are no longer rare in CAP, they are still less likely. Prior stays in healthcare-related environments such as hospitals, nursing homes, or hemodialysis centers or a history of receiving domiciliary care can increase patients' risk for CAP caused by multidrug-resistant bacteria. Health care–associated pneumonia (HCAP) is an infection associated with recent exposure to the health care system, including hospitals, outpatient clinics, nursing homes , dialysis centers, chemotherapy treatment, or home care . HCAP
9516-554: The local agricultural shows, where Potter was often asked to serve as a judge. In 1942 she became President-elect of the Herdwick Sheepbreeders' Association, the first time a woman had been elected, but died before taking office. In one of her diary entries whilst travelling through Wales, Potter complained about the Welsh language . She wrote " Machynlleth , wretched town, hardly a person could speak English", continuing "Welsh seem
9638-431: The lower airways, reflexes of the glottis , actions of complement proteins and immunoglobulins are important for protection. Micro aspiration of contaminated secretions can infect the lower airways and cause pneumonia. The progress of pneumonia is determined by the virulence of the organism; the amount of organism required to start an infection; and the body's immune response against the infection. Most bacteria enter
9760-464: The lungs via small aspirations of organisms residing in the throat or nose. Half of normal people have these small aspirations during sleep. While the throat always contains bacteria, potentially infectious ones reside there only at certain times and under certain conditions. A minority of types of bacteria such as Mycobacterium tuberculosis and Legionella pneumophila reach the lungs via contaminated airborne droplets. Bacteria can also spread via
9882-418: The lungs, many viruses simultaneously affect other organs and thus disrupt other body functions. Viruses also make the body more susceptible to bacterial infections; in this way, bacterial pneumonia can occur at the same time as viral pneumonia. Pneumonia is typically diagnosed based on a combination of physical signs and often a chest X-ray . In adults with normal vital signs and a normal lung examination,
10004-433: The lungs, where they invade the cells lining the airways, alveoli, or lung parenchyma . Some viruses such as measles and herpes simplex may reach the lungs via the blood. The invasion of the lungs may lead to varying degrees of cell death. When the immune system responds to the infection, even more lung damage may occur. Primarily white blood cells, mainly mononuclear cells , generate the inflammation. As well as damaging
10126-400: The lymph nodes in the neck , joint pain , or a middle ear infection . Viral pneumonia presents more commonly with wheezing than bacterial pneumonia. Pneumonia was historically divided into "typical" and "atypical" based on the belief that the presentation predicted the underlying cause. However, evidence has not supported this distinction, therefore it is no longer emphasized. Pneumonia
10248-435: The major Herdwick sheep farmers in the county. She was admired by her shepherds and farm managers for her willingness to experiment with the latest biological remedies for the common diseases of sheep, and for her employment of the best shepherds, sheep breeders, and farm managers. By the late 1920s, Potter and her Hill Top farm manager Tom Storey had made a name for their prize-winning Herdwick flock, which took many prizes at
10370-727: The match because Warne was "in trade" and thus not socially suitable. The engagement lasted only one month—Warne died of pernicious anaemia at age 37. That same year, Potter used some of her income and a small inheritance from an aunt to buy Hill Top Farm in Near Sawrey , located 6 miles (9.7 km) west of Lake Windermere in the English Lake District . Potter and Warne may have hoped that Hill Top Farm would be their holiday home, but after Warne's death, Potter went ahead with its purchase as she had always wanted to own that farm and live in "that charming village". The tenant farmer John Cannon and his family agreed to stay on to manage
10492-524: The most prominent sign. The typical signs and symptoms in children under five are fever, cough, and fast or difficult breathing. Fever is not very specific, as it occurs in many other common illnesses and may be absent in those with severe disease, malnutrition or in the elderly. In addition, a cough is frequently absent in children less than 2 months old. More severe signs and symptoms in children may include blue-tinged skin , unwillingness to drink, convulsions, ongoing vomiting, extremes of temperature, or
10614-536: The new Hentschel three-colour process to reproduce her watercolours. On 2 October 1902, The Tale of Peter Rabbit was published and became an immediate success. It was followed the next year by The Tale of Squirrel Nutkin and The Tailor of Gloucester , which had also first been written as picture letters to the Moore children. Working with Norman Warne as her editor, Potter published two or three little books each year: 23 books in all. The last book in this format
10736-623: The oneness of God and that rejected the doctrine of the Trinity. Potter's paternal grandfather, Edmund Potter , from Glossop in Derbyshire , owned what was then the largest calico printing works in England, and later served as a Member of Parliament. Potter's father, Rupert William Potter (1832–1914), was educated at Manchester College by the Unitarian philosopher James Martineau . He then trained as
10858-431: The other's way of life, both express a decided preference for their own. The book was critically well received. The Johnny Town-Mouse character appeared in a 1971 ballet film, and the tale has been adapted to a BBC television animated series. The country mouse, Timmy Willie, falls asleep in a hamper , and is carried with the vegetables to the city, where the mice, including Johnny Town-Mouse, make him welcome, but finding
10980-552: The outbreak of World War I , Potter persuaded her mother to move to the Lake District, renting her a property in Sawrey. Finding life in Sawrey dull, Helen Potter soon moved to Lindeth Howe (now a 34-bedroomed hotel), a large house the Potters had previously rented for the summer in Bowness , on the other side of Lake Windermere. Potter continued to write stories for Frederick Warne & Co and fully participated in country life. She established
11102-407: The places of extraordinary beauty but also those heads of valleys and low grazing lands that would be irreparably ruined by development." Potter was also an authority on the traditional Lakeland crafts and period furniture, as well as local stonework. She restored and preserved the farms that she bought or managed, making sure that each farm house had in it a piece of antique Lakeland furniture. Potter
11224-421: The probability of Mycoplasma pneumoniae . In general, in adults, investigations are not needed in mild cases. There is a very low risk of pneumonia if all vital signs and auscultation are normal. C-reactive protein (CRP) may help support the diagnosis. For those with CRP less than 20 mg/L without convincing evidence of pneumonia, antibiotics are not recommended. Procalcitonin may help determine
11346-399: The problems of afforestation , preserving the intact grazing lands, and husbanding the quarries and timber on these farms. All her farms were stocked with Herdwick sheep and frequently with Galloway cattle . Potter continued to write stories and to draw, although mostly for her own pleasure. In 1922, Cecily Parsley's Nursery Rhymes , a collection of traditional English nursery rhymes ,
11468-654: The renovated farmhouse on Castle Farm, which was 34 acres (14 ha) large. Hill Top remained a working farm but was now remodelled to allow for the tenant family and Potter's private studio and workshop. At last her own woman, Potter settled into the partnerships that shaped the rest of her life: her country solicitor husband and his large family, her farms, the Sawrey community and the predictable rounds of country life. The Tale of Jemima Puddle-Duck and The Tale of Tom Kitten are representative of Hill Top Farm and her farming life and reflect her happiness with her country life. Her father, Rupert Potter, died in 1914, and with
11590-497: The responsible pathogen can be difficult. Diagnosis is often based on symptoms and physical examination . Chest X-rays , blood tests, and culture of the sputum may help confirm the diagnosis. The disease may be classified by where it was acquired, such as community- or hospital-acquired or healthcare-associated pneumonia. Risk factors for pneumonia include cystic fibrosis , chronic obstructive pulmonary disease (COPD), sickle cell disease , asthma , diabetes , heart failure,
11712-500: The responsible pathogen. Most patients (62%) had no detectable pathogens in their sample, and unexpectedly, respiratory viruses were detected more frequently than bacteria. Specifically, 23% had one or more viruses, 11% had one or more bacteria, 3% had both bacterial and viral pathogens, and 1% had a fungal or mycobacterial infection. "The most common pathogens were human rhinovirus (in 9% of patients), influenza virus (in 6%), and Streptococcus pneumoniae (in 5%)." The term pneumonia
11834-519: The risk of community acquired pneumonia in people with chronic obstructive pulmonary disease, but does not reduce mortality or the risk of hospitalization for people with this condition. People with COPD are recommended by a number of guidelines to have a pneumococcal vaccination. Other vaccines for which there is support for a protective effect against pneumonia include pertussis , varicella , and measles . When influenza outbreaks occur, medications such as amantadine or rimantadine may help prevent
11956-521: The risk of viral pneumonia among their patients. Vaccinations against Haemophilus influenzae and Streptococcus pneumoniae have good evidence to support their use. There is strong evidence for vaccinating children under the age of 2 against Streptococcus pneumoniae ( pneumococcal conjugate vaccine ). Vaccinating children against Streptococcus pneumoniae has led to a decreased rate of these infections in adults, because many adults acquire infections from children. A Streptococcus pneumoniae vaccine
12078-629: The same in Potter and who was to have a lasting impact on her life. At about the age of 14, Potter began to keep a diary, written in a simple substitution cipher of her own devising. Her Journal was important to the development of her creativity, serving as both sketchbook and literary experiment. In tiny handwriting, she reported on society, recorded her impressions of art and artists, recounted stories and observed life around her. The Journal , deciphered and transcribed by Leslie Linder in 1958, does not provide an intimate record of her personal life, but it
12200-545: The same printer bought several more drawings for Weatherly's Our Dear Relations , another book of rhymes, and the following year Potter sold a series of frog illustrations and verses for Changing Pictures , a popular annual offered by the art publisher Ernest Nister. Potter was pleased by this success and determined to publish her own illustrated stories. Whenever Potter went on holiday to the Lake District or Scotland , she sent letters to young friends, illustrating them with quick sketches. Many of these letters were written to
12322-527: The signs and symptoms; however, confirmation of an influenza infection requires testing. Thus, treatment is frequently based on the presence of influenza in the community or a rapid influenza test . Adults 65 years old or older, as well as cigarette smokers and people with ongoing medical conditions are at increased risk for pneumonia. Physical examination may sometimes reveal low blood pressure , high heart rate , or low oxygen saturation . The respiratory rate may be faster than normal, and this may occur
12444-468: The single biggest risk factor for pneumococcal pneumonia in otherwise-healthy adults. Hand hygiene and coughing into one's sleeve may also be effective preventative measures. Wearing surgical masks by the sick may also prevent illness. Appropriately treating underlying illnesses (such as HIV/AIDS, diabetes mellitus , and malnutrition) can decrease the risk of pneumonia. In children less than 6 months of age, exclusive breast feeding reduces both
12566-732: The story of the first publication and many editions. Potter's country life, her farming and role as a landscape preservationist are discussed in the work of Matthew Kelly, The Women Who Saved the English Countryside (2022). See also Susan Denyer and authors in the publications of The National Trust , such as Beatrix Potter at Home in the Lake District (2004). Potter's work as a scientific illustrator and her work in mycology are discussed in Linda Lear 's books Beatrix Potter: A Life in Nature (2006) and Beatrix Potter: The Extraordinary Life of
12688-565: The twenty months he survived her. When he died in August 1945, he left the remainder to the National Trust. Potter left almost all the original illustrations for her books to the National Trust. The copyright to her stories and merchandise was then given to her publisher Frederick Warne & Co, now a division of the Penguin Group . On 1 January 2014, the copyright expired in the UK and other countries with
12810-496: The virus or its antigens with culture or polymerase chain reaction (PCR), among other techniques. Mycoplasma , Legionella , Streptococcus , and Chlamydia can also be detected using PCR techniques on bronchoalveolar lavage and nasopharyngeal swab . The causative agent is determined in only 15% of cases with routine microbiological tests. Pneumonitis refers to lung inflammation; pneumonia refers to pneumonitis, usually due to infection but sometimes non-infectious, that has
12932-462: The world in many languages with her stories being retold in songs, films, ballet, and animations, and her life is depicted in two films – The Tales of Beatrix Potter (1983) and Miss Potter (2006). Potter's family on both sides were from the Manchester area. They were English Unitarians , associated with dissenting Protestant congregations, influential in 19th-century Britain, that affirmed
13054-473: Was Cecily Parsley's Nursery Rhymes in 1922, a collection of favourite rhymes. Although The Tale of Little Pig Robinson was not published until 1930, it had been written much earlier. Potter continued creating her little books until after the First World War when her energies were increasingly directed toward her farming, sheep-breeding, and land conservation. The immense popularity of Potter's books
13176-510: Was a regular visitor to the art galleries of London, particularly enjoying the summer and winter exhibitions at the Royal Academy in London. Her Journal reveals her growing sophistication as a critic as well as the influence of her father's friend, the artist Sir John Everett Millais , who recognised Potter's talent of observation. Although Potter was aware of art and artistic trends, her drawing and her prose style were uniquely her own. As
13298-399: Was an English writer, illustrator , natural scientist , and conservationist . She is best known for her children's books featuring animals, such as The Tale of Peter Rabbit , which was her first commercially published work in 1902. Her books, including The Tale of Jemima Puddle Duck and The Tale of Tom Kitten , have sold more than 250 million copies. An entrepreneur, Potter was
13420-684: Was based on the lively quality of her illustrations, the non-didactic nature of her stories, the depiction of the rural countryside, and the imaginative qualities she lent to her animal characters. Potter was also a canny businesswoman. As early as 1903, she made and patented a Peter Rabbit doll. It was followed by other merchandise over the years, including painting books, board games, wall-paper, figurines, baby blankets and china tea-sets. All were licensed by Frederick Warne & Co and earned Potter an independent income, as well as immense profits for her publisher. In 1905, Potter and Norman Warne became unofficially engaged. Potter's parents objected to
13542-460: Was destroyed in the Blitz . Bousfield Primary School now stands where the house once was. A blue plaque on the school building testifies to the former site of the Potter home. Both parents were artistically talented, and Rupert was an adept amateur photographer. Rupert had invested in the stock market, and by the early 1890s, he was extremely wealthy. Beatrix Potter was educated by three governesses,
13664-617: Was drawn in black and white with a coloured frontispiece. Rawnsley had great faith in Potter's tale, recast it in didactic verse, and made the rounds of the London publishing houses. Frederick Warne & Co had previously rejected the tale but, eager to compete in the booming small format children's book market, reconsidered and accepted the "bunny book" (as the firm called it) following the recommendation of their prominent children's book artist L. Leslie Brooke . The firm declined Rawnsley's verse in favour of Potter's original prose, and Potter agreed to colour her pen and ink illustrations, choosing
13786-481: Was featured in the film Lorenzo's Oil . Pneumonia Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli . Symptoms typically include some combination of productive or dry cough , chest pain , fever, and difficulty breathing . The severity of the condition is variable. Pneumonia is usually caused by infection with viruses or bacteria, and less commonly by other microorganisms . Identifying
13908-581: Was interested in every branch of natural science except astronomy . Botany was a passion for most Victorians , and nature study was a popular enthusiasm. She collected fossils, studied archaeological artefacts from London excavations, and was interested in entomology . In all these areas, she drew and painted her specimens with increasing skill. By the 1890s, her scientific interests centred on mycology . First drawn to fungi because of their colours and evanescence in nature and her delight in painting them, her interest deepened after meeting Charles McIntosh,
14030-562: Was interested in preserving not only the Herdwick sheep but also the way of life of fell farming. In 1930 the Heelises became partners with the National Trust in buying and managing the fell farms included in the large Monk Coniston Estate. The estate was composed of many farms spread over a wide area of north-western Lancashire, including the Tarn Hows . Potter was the de facto estate manager for
14152-463: Was more interested in Tenniel 's illustrations than what they were about. The Brer Rabbit stories of Joel Chandler Harris had been family favourites, and she later studied his Uncle Remus stories and illustrated them. She studied book illustration from a young age and developed her own tastes, but the work of the picture book triumvirate Walter Crane , Kate Greenaway and Randolph Caldecott ,
14274-511: Was published 1 September 2016, to mark the 150th anniversary of Potter's birth. Also in 2016, Peter Rabbit was depicted on the reverse of a British fifty pence coin , and Peter along with other Potter characters featured on a series of UK postage stamps issued by the Royal Mail . In 2017, The Art of Beatrix Potter: Sketches, Paintings, and Illustrations by Emily Zach was published after San Francisco publisher Chronicle Books decided to mark
14396-955: Was published posthumously by The Horn Book Magazine in 1944. Potter was a generous patron of the Girl Guides , whose troops she allowed to make their summer encampments on her land, and whose company she enjoyed as an older woman. Potter and William Heelis enjoyed a happy marriage of thirty years, continuing their farming and preservation efforts throughout the hard days of World War II . Although they were childless, Potter played an important role in William's large family, particularly enjoying her relationship with several nieces whom she helped educate, and giving comfort and aid to her husband's brothers and sisters. Potter died of complications from pneumonia and heart disease on 22 December 1943 at Castle Cottage, and her remains were cremated at Carleton Crematorium , Blackpool. She left nearly all her property to
14518-457: Was published. Her books in the late 1920s included the semi-autobiographical The Fairy Caravan , a fanciful tale set in her beloved Troutbeck fells . It was published only in the US during Potter's lifetime, and not until 1952 in the UK. Sister Anne , Potter's version of the story of Bluebeard , was written for her American readers, but illustrated by Katharine Sturges. A final folktale, Wag by Wall ,
14640-478: Was reported in July 2014 that Potter had personally given a number of her own original hand-painted illustrations to the two daughters of Arthur and Harriet Lupton, who were cousins to both Beatrix Potter and Catherine, Princess of Wales . Potter's parents lived comfortably at 2 Bolton Gardens, West Brompton , London, where Helen Beatrix was born on 28 July 1866 and her brother Walter Bertram on 14 March 1872. The house
14762-577: Was searching for more independent activities and wished to earn some money of her own while dutifully taking care of her parents, dealing with her especially demanding mother, and managing their various households. In the Victorian era , women of her class were privately educated and rarely went to university. Potter's parents encouraged her higher education, but the social norms of the time limited her academic career within Britain's institutions. Beatrix Potter
14884-460: Was the first author to license fictional characters to a range of toys and household objects still on sale today". In an article by the Smithsonian magazine titled, How Beatrix Potter Invented Character Merchandising , Joy Lanzendorfer writes, "Potter was also an entrepreneur and a pioneer in licensing and merchandising literary characters. Potter built a retail empire out of her “bunny book” that
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