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124-512: The origin of the Chabo is unknown. Mitochondrial DNA evidence suggests that it, and all other Japanese breeds of ornamental chicken, derived through selective breeding from fighting chickens , the ancestors of the modern Shamo breeds. The earliest recognisable depiction of a Chabo in Japanese art dates from the beginning of the seventeenth century; a short-legged chicken with tall upright tail shown in

248-499: A critical perspective. The kind of issues addressed and implications for the approach involve pondering why, if a key development goal is to alleviate poverty, is poverty increasing? Why is there such a gap between plans and outcomes? Why are those working in development so willing to disregard history and the lessons it might offer? Why is development so externally driven rather than having an internal basis? In short, why does so much planned development fail? Kinship can refer both to

372-605: A culture from an emic (conceptual, vs. etic , or technical) point of view. The study of kinship and social organization is a central focus of sociocultural anthropology, as kinship is a human universal . Sociocultural anthropology also covers economic and political organization , law and conflict resolution, patterns of consumption and exchange, material culture, technology, infrastructure, gender relations, ethnicity, childrearing and socialization, religion, myth, symbols, values, etiquette, worldview, sports, music, nutrition, recreation, games, food, festivals, and language (which

496-585: A database) to determine maternal lineage. Most often, the comparison is made with the revised Cambridge Reference Sequence . Vilà et al. have published studies tracing the matrilineal descent of domestic dogs from wolves. The concept of the Mitochondrial Eve is based on the same type of analysis, attempting to discover the origin of humanity by tracking the lineage back in time. Entities subject to uniparental inheritance and with little to no recombination may be expected to be subject to Muller's ratchet ,

620-411: A diffuse assemblage of ethnology, human biology, comparative linguistics, and prehistory, held together mainly by the vested interests, sunk costs, and administrative habits of academia, and by a romantic image of comprehensive scholarship. Sociocultural anthropology has been heavily influenced by structuralist and postmodern theories, as well as a shift toward the analysis of modern societies. During

744-500: A donor female, and nuclear DNA from the mother and father. In the spindle transfer procedure, the nucleus of an egg is inserted into the cytoplasm of an egg from a donor female which has had its nucleus removed, but still contains the donor female's mtDNA. The composite egg is then fertilized with the male's sperm. The procedure is used when a woman with genetically defective mitochondria wishes to procreate and produce offspring with healthy mitochondria. The first known child to be born as

868-669: A few major subdivisions to dozens more. Practical anthropology, the use of anthropological knowledge and technique to solve specific problems, has arrived; for example, the presence of buried victims might stimulate the use of a forensic archaeologist to recreate the final scene. The organization has also reached a global level. For example, the World Council of Anthropological Associations (WCAA), "a network of national, regional and international associations that aims to promote worldwide communication and cooperation in anthropology", currently contains members from about three dozen nations. Since

992-435: A finding that has been rejected by other scientists. In sexual reproduction , mitochondria are normally inherited exclusively from the mother; the mitochondria in mammalian sperm are usually destroyed by the egg cell after fertilization. Also, mitochondria are present solely in the midpiece, which is used for propelling the sperm cells, and sometimes the midpiece, along with the tail, is lost during fertilization. In 1999 it

1116-545: A healthy human sperm has been reported to contain on average 5 molecules), degradation of sperm mtDNA in the male genital tract and in the fertilized egg; and, at least in a few organisms, failure of sperm mtDNA to enter the egg. Whatever the mechanism, this single parent ( uniparental inheritance ) pattern of mtDNA inheritance is found in most animals, most plants and also in fungi. In a study published in 2018, human babies were reported to inherit mtDNA from both their fathers and their mothers resulting in mtDNA heteroplasmy ,

1240-542: A mutation in mtDNA has been used to help diagnose prostate cancer in patients with negative prostate biopsy . mtDNA alterations can be detected in the bio-fluids of patients with cancer. mtDNA is characterized by the high rate of polymorphisms and mutations. Some of which are increasingly recognized as an important cause of human pathology such as oxidative phosphorylation (OXPHOS) disorders, maternally inherited diabetes and deafness (MIDD), Type 2 diabetes mellitus, Neurodegenerative disease , heart failure and cancer. Though

1364-626: A mutational (contrary to the selective one) explanation for the observation that long-lived species have GC-rich mtDNA: long-lived species become GC-rich simply because of their biased process of mutagenesis. An association between mtDNA mutational spectrum and species-specific life-history traits in mammals opens a possibility to link these factors together discovering new life-history-specific mutagens in different groups of organisms. Deletion breakpoints frequently occur within or near regions showing non-canonical (non-B) conformations, namely hairpins, cruciforms and cloverleaf-like elements. Moreover, there

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1488-636: A number of types are recognised. These include the Okina Chabo, which is bearded; two varieties of Higo-Chabo, the Dorama and Taikan, both with an unusually large comb (the Taikan has a normal Chabo tail, that of the Dorama is shorter); and the Shinguro Chabo or black-skinned black, which is entirely black, with black skin like that of a Silkie. Mitochondrial DNA Mitochondrial DNA ( mtDNA and mDNA )

1612-410: A result of illness. On the other hand, there are fields that intersect with medical anthropology in terms of research methodology and theoretical production, such as cultural psychiatry and transcultural psychiatry or ethnopsychiatry . Nutritional anthropology is a synthetic concept that deals with the interplay between economic systems , nutritional status and food security , and how changes in

1736-521: A result of mitochondrial donation was a boy born to a Jordanian couple in Mexico on 6 April 2016. The concept that mtDNA is particularly susceptible to reactive oxygen species generated by the respiratory chain due to its proximity remains controversial. mtDNA does not accumulate any more oxidative base damage than nuclear DNA. It has been reported that at least some types of oxidative DNA damage are repaired more efficiently in mitochondria than they are in

1860-507: A role in the mitochondrial bottleneck, exploiting cell-to-cell variability to ameliorate the inheritance of damaging mutations. According to Justin St. John and colleagues, "At the blastocyst stage, the onset of mtDNA replication is specific to the cells of the trophectoderm . In contrast, the cells of the inner cell mass restrict mtDNA replication until they receive the signals to differentiate to specific cell types." The two strands of

1984-459: A significantly different form, in most non-Western contexts. To surmount this difficulty, anthropologists of art have focused on formal features in objects which, without exclusively being 'artistic', have certain evident 'aesthetic' qualities. Boas' Primitive Art , Claude Lévi-Strauss ' The Way of the Masks (1982) or Geertz's 'Art as Cultural System' (1983) are some examples in this trend to transform

2108-435: A species and also for identifying and quantifying the phylogeny (evolutionary relationships; see phylogenetics ) among different species. To do this, biologists determine and then compare the mtDNA sequences from different individuals or species. Data from the comparisons is used to construct a network of relationships among the sequences, which provides an estimate of the relationships among the individuals or species from which

2232-623: A stabilisation or reduction in mutant load between generations. The mechanism underlying the bottleneck is debated, with a recent mathematical and experimental metastudy providing evidence for a combination of the random partitioning of mtDNAs at cell divisions and the random turnover of mtDNA molecules within the cell. Male mitochondrial DNA inheritance has been discovered in Plymouth Rock chickens . Evidence supports rare instances of male mitochondrial inheritance in some mammals as well. Specifically, documented occurrences exist for mice, where

2356-463: A wide variety of fields, such as teaching, politics, cultural anthropology etc. While the origins of ethnomusicology date back to the 18th and 19th centuries, it was formally termed "ethnomusicology" by Dutch scholar Jaap Kunst c.  1950 . Later, the influence of study in this area spawned the creation of the periodical Ethnomusicology and the Society of Ethnomusicology . Visual anthropology

2480-532: Is a linear genome made up of homogeneous DNA molecules (type 5). Great variation in mtDNA gene content and size exists among fungi and plants, although there appears to be a core subset of genes present in all eukaryotes (except for the few that have no mitochondria at all). In Fungi, however, there is no single gene shared among all mitogenomes. Some plant species have enormous mitochondrial genomes, with Silene conica mtDNA containing as many as 11,300,000 base pairs. Surprisingly, even those huge mtDNAs contain

2604-521: Is a method of analysing social or cultural interaction. It often involves participant observation though an ethnographer may also draw from texts written by participants of in social interactions. Ethnography views first-hand experience and social context as important. Tim Ingold distinguishes ethnography from anthropology arguing that anthropology tries to construct general theories of human experience, applicable in general and novel settings, while ethnography concerns itself with fidelity. He argues that

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2728-447: Is a type of archaeology that studies the practices and material remains of living human groups in order to gain a better understanding of the evidence left behind by past human groups, who are presumed to have lived in similar ways. Linguistic anthropology (not to be confused with anthropological linguistics ) seeks to understand the processes of human communications, verbal and non-verbal, variation in language across time and space,

2852-467: Is a well-established marker of oxidative DNA damage. In persons with amyotrophic lateral sclerosis (ALS), the enzymes that normally repair 8-oxoG DNA damages in the mtDNA of spinal motor neurons are impaired. Thus oxidative damage to mtDNA of motor neurons may be a significant factor in the etiology of ALS. Over the past decade, an Israeli research group led by Professor Vadim Fraifeld has shown that strong and significant correlations exist between

2976-515: Is also the object of study in linguistic anthropology). Comparison across cultures is a key element of method in sociocultural anthropology, including the industrialized (and de-industrialized) West. The Standard Cross-Cultural Sample (SCCS) includes 186 such cultures. Biological anthropology and physical anthropology are synonymous terms to describe anthropological research focused on the study of humans and non-human primates in their biological, evolutionary, and demographic dimensions. It examines

3100-439: Is an interdisciplinary subfield of anthropology that studies the interaction of cultural and mental processes . This subfield tends to focus on ways in which humans' development and enculturation within a particular cultural group – with its own history, language, practices, and conceptual categories – shape processes of human cognition , emotion , perception , motivation , and mental health . It also examines how

3224-537: Is caused by the creeper gene , Cp , which displays the standard behaviour of recessive lethal alleles : when short-legged birds are bred, 25% of the embryos are homozygous for the lethal allele, and die in shell; 50% are heterozygous , and develop into short-legged birds; the remaining 25% are homozygous for the non-lethal allele, and develop longer legs, making them unsuitable for showing. Long-legged birds bred to each other can not produce short-legged offspring. In western countries there are many colour varieties of

3348-584: Is concerned, in part, with the study and production of ethnographic photography, film and, since the mid-1990s, new media . While the term is sometimes used interchangeably with ethnographic film , visual anthropology also encompasses the anthropological study of visual representation, including areas such as performance, museums, art, and the production and reception of mass media . Visual representations from all cultures, such as sandpaintings, tattoos, sculptures and reliefs, cave paintings, scrimshaw, jewelry, hieroglyphs, paintings, and photographs are included in

3472-487: Is data supporting the involvement of helix-distorting intrinsically curved regions and long G-tetrads in eliciting instability events. In addition, higher breakpoint densities were consistently observed within GC-skewed regions and in the close vicinity of the degenerate sequence motif YMMYMNNMMHM. Unlike nuclear DNA, which is inherited from both parents and in which genes are rearranged in the process of recombination , there

3596-456: Is more related to philosophy , literature and the arts (how one's culture affects the experience for self and group, contributing to a more complete understanding of the people's knowledge, customs, and institutions), while social anthropology is more related to sociology and history. In that, it helps develop an understanding of social structures, typically of others and other populations (such as minorities, subgroups, dissidents, etc.). There

3720-414: Is no hard-and-fast distinction between them, and these categories overlap to a considerable degree. Inquiry in sociocultural anthropology is guided in part by cultural relativism , the attempt to understand other societies in terms of their own cultural symbols and values. Accepting other cultures in their own terms moderates reductionism in cross-cultural comparison. This project is often accommodated in

3844-514: Is observed in bivalve mollusks. In those species, females have only one type of mtDNA (F), whereas males have F type mtDNA in their somatic cells, but M type of mtDNA (which can be as much as 30% divergent) in germline cells. Paternally inherited mitochondria have additionally been reported in some insects such as fruit flies , honeybees , and periodical cicadas . An IVF technique known as mitochondrial donation or mitochondrial replacement therapy (MRT) results in offspring containing mtDNA from

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3968-509: Is one hypothesis for why some genes are retained in mtDNA; colocalisation for redox regulation is another, citing the desirability of localised control over mitochondrial machinery. Recent analysis of a wide range of mtDNA genomes suggests that both these features may dictate mitochondrial gene retention. Across all organisms, there are six main mitochondrial genome types, classified by structure (i.e. circular versus linear), size, presence of introns or plasmid like structures , and whether

4092-934: Is one of its primary research designs as well as the text that is generated from anthropological fieldwork. In Great Britain and the Commonwealth countries, the British tradition of social anthropology tends to dominate. In the United States, anthropology has traditionally been divided into the four field approach developed by Franz Boas in the early 20th century: biological or physical anthropology ; social , cultural , or sociocultural anthropology ; archaeological anthropology ; and linguistic anthropology . These fields frequently overlap but tend to use different methodologies and techniques. European countries with overseas colonies tended to practice more ethnology (a term coined and defined by Adam F. Kollár in 1783). It

4216-540: Is severely degraded. Autosomal cells only have two copies of nuclear DNA, but can have hundreds of copies of mtDNA due to the multiple mitochondria present in each cell. This means highly degraded evidence that would not be beneficial for STR analysis could be used in mtDNA analysis. mtDNA may be present in bones, teeth, or hair, which could be the only remains left in the case of severe degradation. In contrast to STR analysis, mtDNA sequencing uses Sanger sequencing . The known sequence and questioned sequence are both compared to

4340-457: Is sometimes referred to as sociocultural anthropology in the parts of the world that were influenced by the European tradition. Anthropology is a global discipline involving humanities, social sciences and natural sciences. Anthropology builds upon knowledge from natural sciences , including the discoveries about the origin and evolution of Homo sapiens , human physical traits, human behavior ,

4464-518: Is the DNA located in the mitochondria organelles in a eukaryotic cell that converts chemical energy from food into adenosine triphosphate (ATP). Mitochondrial DNA is a small portion of the DNA contained in a eukaryotic cell; most of the DNA is in the cell nucleus , and, in plants and algae, the DNA also is found in plastids , such as chloroplasts . Human mitochondrial DNA was the first significant part of

4588-485: Is the first multicellular organism known to have this absence of aerobic respiration and live completely free of oxygen dependency. There are three different mitochondrial genome types in plants and fungi. The first type is a circular genome that has introns (type 2) and may range from 19 to 1000 kbp in length. The second genome type is a circular genome (about 20–1000 kbp) that also has a plasmid-like structure (1 kb) (type 3). The final genome type found in plants and fungi

4712-500: Is the people they share DNA with. This is called consanguinity or "blood ties". People can also have a chosen family in which they chose who they want to be a part of their family. In some cases, people are closer with their chosen family more than with their biological families. Feminist anthropology is a four field approach to anthropology ( archeological , biological , cultural , linguistic ) that seeks to reduce male bias in research findings, anthropological hiring practices, and

4836-452: Is used in an analogous way to determine the patrilineal history.) This is usually accomplished on human mitochondrial DNA by sequencing the hypervariable control regions (HVR1 or HVR2), and sometimes the complete molecule of the mitochondrial DNA, as a genealogical DNA test . HVR1, for example, consists of about 440 base pairs. These 440 base pairs are compared to the same regions of other individuals (either specific people or subjects in

4960-510: Is usually no change in mtDNA from parent to offspring. Although mtDNA also recombines, it does so with copies of itself within the same mitochondrion. Because of this and because the mutation rate of animal mtDNA is higher than that of nuclear DNA, mtDNA is a powerful tool for tracking ancestry through females ( matrilineage ) and has been used in this role to track the ancestry of many species back hundreds of generations. mtDNA testing can be used by forensic scientists in cases where nuclear DNA

5084-517: The POLG2 gene. The replisome machinery is formed by DNA polymerase, TWINKLE and mitochondrial SSB proteins . TWINKLE is a helicase , which unwinds short stretches of dsDNA in the 5' to 3' direction. All these polypeptides are encoded in the nuclear genome. During embryogenesis , replication of mtDNA is strictly down-regulated from the fertilized oocyte through the preimplantation embryo. The resulting reduction in per-cell copy number of mtDNA plays

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5208-606: The Islamic Golden Age . As such, anthropology has been central in the development of several new (late 20th century) interdisciplinary fields such as cognitive science , global studies , and various ethnic studies . According to Clifford Geertz , ...anthropology is perhaps the last of the great nineteenth-century conglomerate disciplines still for the most part organizationally intact. Long after natural history, moral philosophy, philology, and political economy have dissolved into their specialized successors, it has remained

5332-570: The Portrait of Jacoba Maria van Wassenaer by Jan Steen , painted in about 1660, is believed to be a Chabo. Japan was effectively closed to all foreign trade from 1636 until about the time of the Meiji Restoration in 1868. The first documented exports of the Chabo to Europe and the United States began at about this time. The Japanese Bantam apparently reached the United Kingdom in the 1860s; it

5456-461: The University of Copenhagen , defined l'anthropologie as follows: Anthropology, that is to say the science that treats of man, is divided ordinarily and with reason into Anatomy, which considers the body and the parts, and Psychology, which speaks of the soul. Sporadic use of the term for some of the subject matter occurred subsequently, such as the use by Étienne Serres in 1839 to describe

5580-413: The eukaryotic nucleus during evolution . The reasons mitochondria have retained some genes are debated. The existence in some species of mitochondrion-derived organelles lacking a genome suggests that complete gene loss is possible, and transferring mitochondrial genes to the nucleus has several advantages. The difficulty of targeting remotely-produced hydrophobic protein products to the mitochondrion

5704-492: The global financial system from an anthropological perspective. Political economy in anthropology is the application of the theories and methods of historical materialism to the traditional concerns of anthropology, including, but not limited to, non-capitalist societies. Political economy introduced questions of history and colonialism to ahistorical anthropological theories of social structure and culture. Three main areas of interest rapidly developed. The first of these areas

5828-586: The human genome to be sequenced. This sequencing revealed that human mtDNA has 16,569 base pairs and encodes 13 proteins . As in other vertebrates, the human mitochondrial genetic code differs slightly from nuclear DNA. Since animal mtDNA evolves faster than nuclear genetic markers, it represents a mainstay of phylogenetics and evolutionary biology . It also permits tracing the relationships of populations, and so has become important in anthropology and biogeography . Nuclear and mitochondrial DNA are thought to have separate evolutionary origins, with

5952-540: The 1960s", the only African American female anthropologist who was also a Caribbeanist . She studied ethnic and family relations in the Caribbean as well as the United States, and thereby tried to improve the way black life, experiences, and culture were studied. However, Zora Neale Hurston, although often primarily considered to be a literary author, was trained in anthropology by Franz Boas, and published Tell my Horse about her "anthropological observations" of voodoo in

6076-411: The 1970s and 1990s, there was an epistemological shift away from the positivist traditions that had largely informed the discipline. During this shift, enduring questions about the nature and production of knowledge came to occupy a central place in cultural and social anthropology. In contrast, archaeology and biological anthropology remained largely positivist. Due to this difference in epistemology,

6200-526: The 1998 United States court case of Commonwealth of Pennsylvania v. Patricia Lynne Rorrer, mitochondrial DNA was admitted into evidence in the State of Pennsylvania for the first time. The case was featured in episode 55 of season 5 of the true crime drama series Forensic Files (season 5) . Anthropology Anthropology is the scientific study of humanity, concerned with human behavior , human biology , cultures , societies , and linguistics , in both

6324-459: The 75 faculty members were under a department named anthropology. Anthropology as a specialized field of academic study developed much through the end of the 19th century. Then it rapidly expanded beginning in the early 20th century to the point where many of the world's higher educational institutions typically included anthropology departments. Thousands of anthropology departments have come into existence, and anthropology has also diversified from

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6448-467: The Caribbean (1938). Feminist anthropology is inclusive of the anthropology of birth as a specialization, which is the anthropological study of pregnancy and childbirth within cultures and societies. Medical anthropology is an interdisciplinary field which studies "human health and disease, health care systems, and biocultural adaptation". It is believed that William Caudell was the first to discover

6572-527: The Italian Society of Anthropology and Ethnology (1871), and many others subsequently. The majority of these were evolutionists. One notable exception was the Berlin Society for Anthropology, Ethnology, and Prehistory (1869) founded by Rudolph Virchow , known for his vituperative attacks on the evolutionists. Not religious himself, he insisted that Darwin's conclusions lacked empirical foundation. During

6696-649: The Japanese Bantam. The Entente Européenne lists forty-two, of which twenty-three are recognised, with standardised colours including birchen grey, black, black mottled, black-tailed buff, black-tailed white, blue, blue mottled, blue-red, brown-red, buff Columbian, cuckoo, dark grey, golden duckwing, grey, lavender, Miller's grey, partridge, red, red mottled, silver-grey, tri-coloured, wheaten and white. The American Poultry Association lists nine colours. There are also frizzle -feathered, Silkie -feathered and hen-feathered variations, though not in all colours. In Japan

6820-558: The Revised Cambridge Reference Sequence to generate their respective haplotypes. If the known sample sequence and questioned sequence originated from the same matriline, one would expect to see identical sequences and identical differences from the rCRS. Cases arise where there are no known samples to collect and the unknown sequence can be searched in a database such as EMPOP. The Scientific Working Group on DNA Analysis Methods recommends three conclusions for describing

6944-649: The Western world. Exploring and addressing that double bias against women from marginalized racial or ethnic groups is of particular interest in intersectional feminist anthropology. Feminist anthropologists have stated that their publications have contributed to anthropology, along the way correcting against the systemic biases beginning with the "patriarchal origins of anthropology (and (academia)" and note that from 1891 to 1930 doctorates in anthropology went to males more than 85%, more than 81% were under 35, and only 7.2% to anyone over 40 years old, thus reflecting an age gap in

7068-543: The accumulation of deleterious mutations until functionality is lost. Animal populations of mitochondria avoid this through a developmental process known as the mtDNA bottleneck . The bottleneck exploits random processes in the cell to increase the cell-to-cell variability in mutant load as an organism develops: a single egg cell with some proportion of mutant mtDNA thus produces an embryo in which different cells have different mutant loads. Cell-level selection may then act to remove those cells with more mutant mtDNA, leading to

7192-419: The accumulation of mtDNA damage in several organs of rats. For example, dietary restriction prevented age-related accumulation of mtDNA damage in the cortex and decreased it in the lung and testis. Increased mt DNA damage is a feature of several neurodegenerative diseases . The brains of individuals with Alzheimer's disease have elevated levels of oxidative DNA damage in both nuclear DNA and mtDNA, but

7316-505: The anthropologist must make his writing consistent with their understanding of literature and other theory but notes that ethnography may be of use to the anthropologists and the fields inform one another. One of the central problems in the anthropology of art concerns the universality of 'art' as a cultural phenomenon. Several anthropologists have noted that the Western categories of 'painting', 'sculpture', or 'literature', conceived as independent artistic activities, do not exist, or exist in

7440-446: The anthropology of 'art' into an anthropology of culturally specific 'aesthetics'. Media anthropology (also known as the anthropology of media or mass media) emphasizes ethnographic studies as a means of understanding producers, audiences, and other cultural and social aspects of mass media. The types of ethnographic contexts explored range from contexts of media production (e.g., ethnographies of newsrooms in newspapers, journalists in

7564-465: The area of research. Cultural anthropology, in particular, has emphasized cultural relativism , holism , and the use of findings to frame cultural critiques. This has been particularly prominent in the United States, from Boas' arguments against 19th-century racial ideology , through Margaret Mead 's advocacy for gender equality and sexual liberation, to current criticisms of post-colonial oppression and promotion of multiculturalism . Ethnography

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7688-517: The biological and social factors that have affected the evolution of humans and other primates, and that generate, maintain or change contemporary genetic and physiological variation. Archaeology is the study of the human past through its material remains. Artifacts, faunal remains, and human altered landscapes are evidence of the cultural and material lives of past societies. Archaeologists examine material remains in order to deduce patterns of past human behavior and cultural practices. Ethnoarchaeology

7812-456: The coding instructions for some proteins, which may have an effect on organism metabolism and/or fitness. Mutations of mitochondrial DNA can lead to a number of illnesses including exercise intolerance and Kearns–Sayre syndrome (KSS), which causes a person to lose full function of heart, eye, and muscle movements. Some evidence suggests that they might be major contributors to the aging process and age-associated pathologies . Particularly in

7936-547: The comparison. It is to be presumed fundamentally that the species, man, is a unity, and that "the same laws of thought are applicable to all men". Waitz was influential among British ethnologists. In 1863, the explorer Richard Francis Burton and the speech therapist James Hunt broke away from the Ethnological Society of London to form the Anthropological Society of London , which henceforward would follow

8060-714: The context of disease, the proportion of mutant mtDNA molecules in a cell is termed heteroplasmy . The within-cell and between-cell distributions of heteroplasmy dictate the onset and severity of disease and are influenced by complicated stochastic processes within the cell and during development. Mutations in mitochondrial tRNAs can be responsible for severe diseases like the MELAS and MERRF syndromes. Mutations in nuclear genes that encode proteins that mitochondria use can also contribute to mitochondrial diseases. These diseases do not follow mitochondrial inheritance patterns, but instead follow Mendelian inheritance patterns. Recently

8184-597: The death of its founder, William Frédéric Edwards , in 1842, it gradually declined in activity until it eventually dissolved in 1862. Meanwhile, the Ethnological Society of New York, currently the American Ethnological Society , was founded on its model in 1842, as well as the Ethnological Society of London in 1843, a break-away group of the Aborigines' Protection Society . These anthropologists of

8308-403: The differences between a known mtDNA sequence and a questioned mtDNA sequence: exclusion for two or more differences between the sequences, inconclusive if there is one nucleotide difference, or cannot exclude if there are no nucleotide differences between the two sequences. The rapid mutation rate (in animals) makes mtDNA useful for assessing genetic relationships of individuals or groups within

8432-626: The differences in animal species maximum life spans in a multiplicative manner (i.e., species maximum life span = their mtDNA GC% * metabolic rate). To support the scientific community in carrying out comparative analyses between mtDNA features and longevity across animals, a dedicated database was built named MitoAge . De novo mutations arise either due to mistakes during DNA replication or due to unrepaired damage caused in turn by endogenous and exogenous mutagens. It has been long believed that mtDNA can be particularly sensitive to damage caused by reactive oxygen species (ROS), however G>T substitutions,

8556-624: The ends of the linear DNA ) with different modes of replication, which have made them interesting objects of research because many of these unicellular organisms with linear mtDNA are known pathogens . Most ( bilaterian ) animals have a circular mitochondrial genome. Medusozoa and calcarea clades however include species with linear mitochondrial chromosomes. With a few exceptions, animals have 37 genes in their mitochondrial DNA: 13 for proteins , 22 for tRNAs , and 2 for rRNAs . Mitochondrial genomes for animals average about 16,000 base pairs in length. The anemone Isarachnanthus nocturnus has

8680-505: The field of ethnography . Ethnography can refer to both a methodology and the product of ethnographic research, i.e. an ethnographic monograph . As a methodology, ethnography is based upon long-term fieldwork within a community or other research site. Participant observation is one of the foundational methods of social and cultural anthropology. Ethnology involves the systematic comparison of different cultures. The process of participant-observation can be especially helpful to understanding

8804-441: The field of medical anthropology. Currently, research in medical anthropology is one of the main growth areas in the field of anthropology as a whole. It focuses on the following six basic fields: Other subjects that have become central to medical anthropology worldwide are violence and social suffering (Farmer, 1999, 2003; Beneduce, 2010) as well as other issues that involve physical and psychological harm and suffering that are not

8928-441: The field, film production) to contexts of media reception, following audiences in their everyday responses to media. Other types include cyber anthropology , a relatively new area of internet research , as well as ethnographies of other areas of research which happen to involve media, such as development work, social movements , or health education. This is in addition to many classic ethnographic contexts, where media such as radio,

9052-478: The focus of visual anthropology. Economic anthropology attempts to explain human economic behavior in its widest historic, geographic and cultural scope. It has a complex relationship with the discipline of economics, of which it is highly critical. Its origins as a sub-field of anthropology begin with the Polish-British founder of anthropology, Bronisław Malinowski , and his French compatriot, Marcel Mauss , on

9176-542: The former affect the latter. If economic and environmental changes in a community affect access to food, food security, and dietary health, then this interplay between culture and biology is in turn connected to broader historical and economic trends associated with globalization. Nutritional status affects overall health status, work performance potential, and the overall potential for economic development (either in terms of human development or traditional western models) for any given group of people. Psychological anthropology

9300-443: The four sub-fields of anthropology have lacked cohesion over the last several decades. Sociocultural anthropology draws together the principal axes of cultural anthropology and social anthropology . Cultural anthropology is the comparative study of the manifold ways in which people make sense of the world around them, while social anthropology is the study of the relationships among individuals and groups. Cultural anthropology

9424-403: The genetic distances of distantly related species. Statistical models that treat substitution rates among codon positions separately, can thus be used to simultaneously estimate phylogenies that contain both closely and distantly related species Mitochondrial DNA was admitted into evidence for the first time ever in a United States courtroom in 1996 during State of Tennessee v. Paul Ware . In

9548-422: The genetic material is a singular molecule or collection of homogeneous or heterogeneous molecules. In many unicellular organisms (e.g., the ciliate Tetrahymena and the green alga Chlamydomonas reinhardtii ), and in rare cases also in multicellular organisms (e.g. in some species of Cnidaria ), the mtDNA is linear DNA . Most of these linear mtDNAs possess telomerase -independent telomeres (i.e.,

9672-477: The hallmark of the oxidative damage in the nuclear genome, are very rare in mtDNA and do not increase with age. Comparing the mtDNA mutational spectra of hundreds of mammalian species, it has been recently demonstrated that species with extended lifespans have an increased rate of A>G substitutions on single-stranded heavy chain. This discovery led to the hypothesis that A>G is a mitochondria-specific marker of age-associated oxidative damage. This finding provides

9796-418: The human group, considered as a whole, in its details, and in relation to the rest of nature". Broca, being what today would be called a neurosurgeon , had taken an interest in the pathology of speech. He wanted to localize the difference between man and the other animals, which appeared to reside in speech. He discovered the speech center of the human brain, today called Broca's area after him. His interest

9920-421: The human mitochondrial DNA are distinguished as the heavy strand and the light strand. The heavy strand is rich in guanine and encodes 12 subunits of the oxidative phosphorylation system, two ribosomal RNAs (12S and 16S), and 14 transfer RNAs (tRNAs). The light strand encodes one subunit, and 8 tRNAs. So, altogether mtDNA encodes for two rRNAs, 22 tRNAs, and 13 protein subunits , all of which are involved in

10044-524: The idea is controversial, some evidence suggests a link between aging and mitochondrial genome dysfunction. In essence, mutations in mtDNA upset a careful balance of reactive oxygen species (ROS) production and enzymatic ROS scavenging (by enzymes like superoxide dismutase , catalase , glutathione peroxidase and others). However, some mutations that increase ROS production (e.g., by reducing antioxidant defenses) in worms increase, rather than decrease, their longevity. Also, naked mole rats , rodents about

10168-462: The initiation of the transcription of the heavy and light strands are located in the main non-coding region of the mtDNA called the displacement loop, the D-loop . There is evidence that the transcription of the mitochondrial rRNAs is regulated by the heavy-strand promoter 1 (HSP1), and the transcription of the polycistronic transcripts coding for the protein subunits are regulated by HSP2. Measurement of

10292-558: The largest mitochondrial genome of any animal at 80,923 bp. The smallest known mitochondrial genome in animals belongs to the comb jelly Vallicula multiformis , which consist of 9,961 bp. In February 2020, a jellyfish-related parasite – Henneguya salminicola – was discovered that lacks a mitochondrial genome but retains structures deemed mitochondrion-related organelles. Moreover, nuclear DNA genes involved in aerobic respiration and in mitochondrial DNA replication and transcription were either absent or present only as pseudogenes . This

10416-482: The last three decades of the 19th century, a proliferation of anthropological societies and associations occurred, most independent, most publishing their own journals, and all international in membership and association. The major theorists belonged to these organizations. They supported the gradual osmosis of anthropology curricula into the major institutions of higher learning. By 1898, 48 educational institutions in 13 countries had some curriculum in anthropology. None of

10540-415: The levels of the mtDNA-encoded RNAs in bovine tissues has shown that there are major differences in the expression of the mitochondrial RNAs relative to total tissue RNA. Among the 12 tissues examined the highest level of expression was observed in heart, followed by brain and steroidogenic tissue samples. As demonstrated by the effect of the trophic hormone ACTH on adrenal cortex cells, the expression of

10664-443: The longevity of species. The application of a mitochondrial-specific ROS scavenger, which lead to a significant longevity of the mice studied, suggests that mitochondria may still be well-implicated in ageing. Extensive research is being conducted to further investigate this link and methods to combat ageing. Presently, gene therapy and nutraceutical supplementation are popular areas of ongoing research. Bjelakovic et al. analyzed

10788-424: The male-inherited mitochondria were subsequently rejected. It has also been found in sheep, and in cloned cattle. Rare cases of male mitochondrial inheritance have been documented in humans. Although many of these cases involve cloned embryos or subsequent rejection of the paternal mitochondria, others document in vivo inheritance and persistence under lab conditions. Doubly uniparental inheritance of mtDNA

10912-525: The mitochondrial genes may be strongly regulated by external factors, apparently to enhance the synthesis of mitochondrial proteins necessary for energy production. Interestingly, while the expression of protein-encoding genes was stimulated by ACTH, the levels of the mitochondrial 16S rRNA showed no significant change. In most multicellular organisms , mtDNA is inherited from the mother (maternally inherited). Mechanisms for this include simple dilution (an egg contains on average 200,000 mtDNA molecules, whereas

11036-480: The mtDNA base composition and animal species-specific maximum life spans. As demonstrated in their work, higher mtDNA guanine + cytosine content ( GC% ) strongly associates with longer maximum life spans across animal species. An additional observation is that the mtDNA GC% correlation with the maximum life spans is independent of the well-known correlation between animal species metabolic rate and maximum life spans. The mtDNA GC% and resting metabolic rate explain

11160-448: The mtDNA derived from the circular genomes of bacteria engulfed by the ancestors of modern eukaryotic cells. This theory is called the endosymbiotic theory . In the cells of extant organisms, the vast majority of the proteins in the mitochondria (numbering approximately 1500 different types in mammals ) are coded by nuclear DNA , but the genes for some, if not most, of them are thought to be of bacterial origin, having been transferred to

11284-833: The mtDNA has approximately 10-fold higher levels than nuclear DNA. It has been proposed that aged mitochondria is the critical factor in the origin of neurodegeneration in Alzheimer's disease. Analysis of the brains of AD patients suggested an impaired function of the DNA repair pathway, which would cause reduce the overall quality of mtDNA. In Huntington's disease , mutant huntingtin protein causes mitochondrial dysfunction involving inhibition of mitochondrial electron transport , higher levels of reactive oxygen species and increased oxidative stress . Mutant huntingtin protein promotes oxidative damage to mtDNA, as well as nuclear DNA, that may contribute to Huntington's disease pathology . The DNA oxidation product 8-oxoguanine (8-oxoG)

11408-558: The mtDNAs were taken. mtDNA can be used to estimate the relationship between both closely related and distantly related species. Due to the high mutation rate of mtDNA in animals, the 3rd positions of the codons change relatively rapidly, and thus provide information about the genetic distances among closely related individuals or species. On the other hand, the substitution rate of mt-proteins is very low, thus amino acid changes accumulate slowly (with corresponding slow changes at 1st and 2nd codon positions) and thus they provide information about

11532-537: The natural history, or paleontology, of man, based on comparative anatomy, and the creation of a chair in anthropology and ethnography in 1850 at the French National Museum of Natural History by Jean Louis Armand de Quatrefages de Bréau . Various short-lived organizations of anthropologists had already been formed. The Société Ethnologique de Paris , the first to use the term ethnology , was formed in 1839 and focused on methodically studying human races. After

11656-428: The nature of gift-giving exchange (or reciprocity ) as an alternative to market exchange. Economic Anthropology remains, for the most part, focused upon exchange. The school of thought derived from Marx and known as Political Economy focuses on production, in contrast. Economic anthropologists have abandoned the primitivist niche they were relegated to by economists, and have now turned to examine corporations, banks, and

11780-449: The nature of man". Following Broca's lead, Waitz points out that anthropology is a new field, which would gather material from other fields, but would differ from them in the use of comparative anatomy, physiology, and psychology to differentiate man from "the animals nearest to him". He stresses that the data of comparison must be empirical, gathered by experimentation. The history of civilization, as well as ethnology, are to be brought into

11904-472: The nucleus. mtDNA is packaged with proteins which appear to be as protective as proteins of the nuclear chromatin. Moreover, mitochondria evolved a unique mechanism which maintains mtDNA integrity through degradation of excessively damaged genomes followed by replication of intact/repaired mtDNA. This mechanism is not present in the nucleus and is enabled by multiple copies of mtDNA present in mitochondria. The outcome of mutation in mtDNA may be an alteration in

12028-487: The oxidative phosphorylation process. Between most (but not all) protein-coding regions, tRNAs are present (see the human mitochondrial genome map ). During transcription, the tRNAs acquire their characteristic L-shape that gets recognized and cleaved by specific enzymes. With the mitochondrial RNA processing, individual mRNA, rRNA, and tRNA sequences are released from the primary transcript. Folded tRNAs therefore act as secondary structure punctuations. The promoters for

12152-610: The past," studies human activity through investigation of physical evidence. It is considered a branch of anthropology in North America and Asia, while in Europe, archaeology is viewed as a discipline in its own right or grouped under other related disciplines, such as history and palaeontology . The abstract noun anthropology is first attested in reference to history . Its present use first appeared in Renaissance Germany in

12276-474: The path of the new anthropology rather than just ethnology. It was the 2nd society dedicated to general anthropology in existence. Representatives from the French Société were present, though not Broca. In his keynote address, printed in the first volume of its new publication, The Anthropological Review , Hunt stressed the work of Waitz, adopting his definitions as a standard. Among the first associates were

12400-466: The plant and fungal genomes also exist in some protists, as do two unique genome types. One of these unique types is a heterogeneous collection of circular DNA molecules (type 4) while the other is a heterogeneous collection of linear molecules (type 6). Genome types 4 and 6 each range from 1–200 kbp in size. The smallest mitochondrial genome sequenced to date is the 5,967 bp mtDNA of the parasite Plasmodium falciparum . Endosymbiotic gene transfer,

12524-455: The present and past, including archaic humans . Social anthropology studies patterns of behavior, while cultural anthropology studies cultural meaning, including norms and values. The term sociocultural anthropology is commonly used today. Linguistic anthropology studies how language influences social life. Biological or physical anthropology studies the biological development of humans. Archaeology , often termed as "anthropology of

12648-441: The press , new media , and television have started to make their presences felt since the early 1990s. Ethnomusicology is an academic field encompassing various approaches to the study of music (broadly defined), that emphasize its cultural, social, material, cognitive, biological, and other dimensions or contexts instead of or in addition to its isolated sound component or any particular repertoire. Ethnomusicology can be used in

12772-495: The process by which genes that were coded in the mitochondrial genome are transferred to the cell's main genome, likely explains why more complex organisms such as humans have smaller mitochondrial genomes than simpler organisms such as protists. Mitochondrial DNA is replicated by the DNA polymerase gamma complex which is composed of a 140 kDa catalytic DNA polymerase encoded by the POLG gene and two 55 kDa accessory subunits encoded by

12896-422: The provision of data, initiation of direct action, and/or the formulation of policy". Applied anthropology is the practical side of anthropological research; it includes researcher involvement and activism within the participating community. It is closely related to development anthropology (distinct from the more critical anthropology of development ). Anthropology of development tends to view development from

13020-451: The pursuit of anthropology by first-wave feminists until later in life. This correction of systemic bias may include mainstream feminist theory , history , linguistics , archaeology , and anthropology. Feminist anthropologists are often concerned with the construction of gender across societies. Gender constructs are of particular interest when studying sexism . According to St. Clair Drake , Vera Mae Green was, until "[w]ell into

13144-457: The result of processes or laws unknown to them then. For them, the publication of Charles Darwin 's On the Origin of Species was the epiphany of everything they had begun to suspect. Darwin himself arrived at his conclusions through comparison of species he had seen in agronomy and in the wild. Darwin and Wallace unveiled evolution in the late 1850s. There was an immediate rush to bring it into

13268-409: The results of 78 studies between 1977 and 2012, involving a total of 296,707 participants, and concluded that antioxidant supplements do not reduce all-cause mortality nor extend lifespan, while some of them, such as beta carotene, vitamin E, and higher doses of vitamin A, may actually increase mortality. In a recent study, it was shown that dietary restriction can reverse ageing alterations by affecting

13392-442: The same number and kinds of genes as related plants with much smaller mtDNAs. The genome of the mitochondrion of the cucumber ( Cucumis sativus ) consists of three circular chromosomes (lengths 1556, 84 and 45 kilobases), which are entirely or largely autonomous with regard to their replication . Protists contain the most diverse mitochondrial genomes, with five different types found in this kingdom. Type 2, type 3 and type 5 of

13516-486: The scholarly production of knowledge. Anthropology engages often with feminists from non-Western traditions, whose perspectives and experiences can differ from those of white feminists of Europe, America, and elsewhere. From the perspective of the Western world , historically such 'peripheral' perspectives have been ignored, observed only from an outsider perspective, and regarded as less-valid or less-important than knowledge from

13640-500: The size of mice , live about eight times longer than mice despite having reduced, compared to mice, antioxidant defenses and increased oxidative damage to biomolecules. Once, there was thought to be a positive feedback loop at work (a 'Vicious Cycle'); as mitochondrial DNA accumulates genetic damage caused by free radicals, the mitochondria lose function and leak free radicals into the cytosol . A decrease in mitochondrial function reduces overall metabolic efficiency. However, this concept

13764-554: The social sciences. Paul Broca in Paris was in the process of breaking away from the Société de biologie to form the first of the explicitly anthropological societies, the Société d'Anthropologie de Paris , meeting for the first time in Paris in 1859. When he read Darwin, he became an immediate convert to Transformisme , as the French called evolutionism . His definition now became "the study of

13888-488: The social uses of language, and the relationship between language and culture. It is the branch of anthropology that brings linguistic methods to bear on anthropological problems, linking the analysis of linguistic forms and processes to the interpretation of sociocultural processes. Linguistic anthropologists often draw on related fields including sociolinguistics , pragmatics , cognitive linguistics , semiotics , discourse analysis , and narrative analysis. Ethnography

14012-604: The study of the patterns of social relationships in one or more human cultures, or it can refer to the patterns of social relationships themselves. Over its history, anthropology has developed a number of related concepts and terms, such as " descent ", " descent groups ", " lineages ", " affines ", " cognates ", and even " fictive kinship ". Broadly, kinship patterns may be considered to include people related both by descent (one's social relations during development), and also relatives by marriage. Within kinship you have two different families. People have their biological families and it

14136-500: The times were liberal, anti-slavery, and pro- human-rights activists. They maintained international connections. Anthropology and many other current fields are the intellectual results of the comparative methods developed in the earlier 19th century. Theorists in diverse fields such as anatomy , linguistics , and ethnology , started making feature-by-feature comparisons of their subject matters, and were beginning to suspect that similarities between animals, languages, and folkways were

14260-491: The variations among different groups of humans, how the evolutionary past of Homo sapiens has influenced its social organization and culture, and from social sciences , including the organization of human social and cultural relations, institutions, social conflicts, etc. Early anthropology originated in Classical Greece and Persia and studied and tried to understand observable cultural diversity, such as by Al-Biruni of

14384-507: The work of Franz Boas and Bronisław Malinowski in the late 19th and early 20th centuries, social anthropology in Great Britain and cultural anthropology in the US have been distinguished from other social sciences by their emphasis on cross-cultural comparisons , long-term in-depth examination of context, and the importance they place on participant-observation or experiential immersion in

14508-580: The works of Magnus Hundt and Otto Casmann . Their Neo-Latin anthropologia derived from the combining forms of the Greek words ánthrōpos ( ἄνθρωπος , " human ") and lógos ( λόγος , " study "). Its adjectival form appeared in the works of Aristotle . It began to be used in English, possibly via French Anthropologie , by the early 18th century. In 1647, the Bartholins , early scholars of

14632-552: The young Edward Burnett Tylor , inventor of cultural anthropology , and his brother Alfred Tylor , a geologist. Previously Edward had referred to himself as an ethnologist; subsequently, an anthropologist. Similar organizations in other countries followed: The Anthropological Society of Madrid (1865), the American Anthropological Association in 1902, the Anthropological Society of Vienna (1870),

14756-457: Was concerned with the "pre-capitalist" societies that were subject to evolutionary "tribal" stereotypes. Sahlin's work on hunter-gatherers as the "original affluent society" did much to dissipate that image. The second area was concerned with the vast majority of the world's population at the time, the peasantry, many of whom were involved in complex revolutionary wars such as in Vietnam. The third area

14880-410: Was conclusively disproved when it was demonstrated that mice, which were genetically altered to accumulate mtDNA mutations at accelerated rate do age prematurely, but their tissues do not produce more ROS as predicted by the 'Vicious Cycle' hypothesis. Supporting a link between longevity and mitochondrial DNA, some studies have found correlations between biochemical properties of the mitochondrial DNA and

15004-468: Was mainly in Biological anthropology , but a German philosopher specializing in psychology, Theodor Waitz , took up the theme of general and social anthropology in his six-volume work, entitled Die Anthropologie der Naturvölker , 1859–1864. The title was soon translated as "The Anthropology of Primitive Peoples". The last two volumes were published posthumously. Waitz defined anthropology as "the science of

15128-670: Was not included in the first British poultry standard of William Tegetmeier in 1865, but was described in his The Poultry Book in 1867. A breed society , the Japanese Bantam Club, was formed during the Crystal Palace Poultry Show of 1912. In 1937 an international breed club – the International Chabo Bantam Club – was formed at a meeting in Switzerland. The Chabo has very short legs. This trait

15252-506: Was on colonialism, imperialism, and the creation of the capitalist world-system . More recently, these political economists have more directly addressed issues of industrial (and post-industrial) capitalism around the world. Applied anthropology refers to the application of the method and theory of anthropology to the analysis and solution of practical problems. It is a "complex of related, research-based, instrumental methods which produce change or stability in specific cultural systems through

15376-460: Was reported that paternal sperm mitochondria (containing mtDNA) are marked with ubiquitin to select them for later destruction inside the embryo . Some in vitro fertilization techniques, particularly injecting a sperm into an oocyte , may interfere with this. The fact that mitochondrial DNA is mostly maternally inherited enables genealogical researchers to trace maternal lineage far back in time. ( Y-chromosomal DNA , paternally inherited,

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