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103-674: The Helodermatidae or beaded lizards are a small family of lizards endemic to North America today, mainly found in the Isthmus of Tehuantepec in Oaxaca, the central lowlands of Chiapas, on the border of Guatemala, and in the Nentón River Valley. But they were formerly more widespread in the ancient past. Traditionally, the Gila monster and the Mexican beaded lizard were the only species recognized, although

206-505: A compartment syndrome . Four potentially lethal toxins have been isolated from the Gila monster's venom, which cause hemorrhage in internal organs and exophthalmos (bulging of the eyes), and helothermine , which causes lethargy , partial paralysis of the limbs, and hypothermia in rats . Some are similar in action of the vasoactive intestinal peptide (VIP), which relaxes smooth muscle and regulates water and electrolyte secretion between

309-399: A 1 kiloton of TNT (4.2 TJ) nuclear bomb dropped on Frenchman Flat on January 27, 1951. The last atmospheric test was conducted on July 17, 1962, and the underground testing of weapons continued until September 23, 1992. The location is known for having the highest concentration of nuclear-detonated weapons in the U.S. Over 80% of the state's area is owned by the federal government. This

412-518: A Gila monster as an Old West outlaw named Bad Bill, voiced by Ray Winstone . The Gila monster has also seen usage as a mascot and state symbol . The official mascot of Eastern Arizona College located in Thatcher, Arizona , is Gila Hank, a gun-toting, cowboy hat-wearing Gila monster. In 2017, the Vegas Golden Knights selected a Gila monster named Chance as their official mascot. In 2019,

515-410: A Gila monster is normally not fatal to healthy adult humans. One fatality has been confirmed since 1930, on February 16, 2024, and the rare fatalities recorded before 1930 occurred in adults who were intoxicated by alcohol or had mismanaged the treatment of the bite. The Gila monster can bite quickly and may not release the victim without intervention. If bitten, the victim may attempt to fully submerge

618-511: A Gila monster. He tied it to his saddle and it bit the middle finger of his right hand and would not let go. A ranch hand pried open the lizard's mouth with a pocket knife, cut open his finger to stimulate bleeding, and then tied saddle strings around his finger and wrist. They summoned Dr. John C. Handy of Tucson, who took Vail back to Tucson for treatment, but Vail experienced swollen and bleeding glands in his throat for sometime afterward. Dr. Handy's friend, Dr. George Goodfellow of Tombstone,

721-402: A U.S. state, just behind Arizona's 128 °F (53 °C) reading and California's 134 °F (57 °C) reading. The vegetation of Nevada is diverse and differs by state area. Nevada contains six biotic zones : alpine , sub-alpine , ponderosa pine , pinion-juniper , sagebrush and creosotebush . Nevada is divided into political jurisdictions designated as counties . Carson City

824-467: A case of Gila monster bite, and I don't want to be. I think a man who is fool enough to get bitten by a Gila monster ought to die. The creature is so sluggish and slow of movement that the victim of its bite is compelled to help largely in order to get bitten." —Dr. Ward, Arizona Graphic , September 23, 1899 In the Old West , the pioneers believed a number of myths about the Gila monster, including that

927-580: A county in 1856 by Utah Territorial Legislature and again in 1861 by the new Nevada Legislature. Clark County is the most populous county in Nevada, accounting for nearly three-quarters of its residents. Las Vegas, Nevada's most populous city, has been the county seat since the county was created in 1909 from a portion of Lincoln County, Nevada . Before that, it was a part of Arizona Territory. Clark County attracts numerous tourists: An estimated 44   million people visited Clark County in 2014. Washoe County

1030-417: A determinate "wavelike" sequence. They change/replace their teeth during their entire life. The Gila monster's bright colors might be suitable to teach predators not to bother this "painful" creature. Because the Gila monster's prey consists mainly of eggs, small animals, and otherwise "helpless" prey, the Gila monster's venom is thought to have evolved for defensive rather than for hunting use. The venom of

1133-597: A dry environment is a slow metabolism, allowing them to use less than half the amount of energy expected for lizards of their size. Gila monsters, and possibly also the Mexican beaded lizard , store water in their urinary bladder and reabsorb it across the bladder epithelium. Their tail is used for energy storage in the form of fat. The Gila monster's diet consists of a variety of food items – small mammals (such as young rabbits , hares , mice , ground squirrels , and other rodents ), small birds , snakes , lizards, frogs , insects , other invertebrates , carrion , and

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1236-572: A favorable microclimate and adequate humidity. Gila monsters rely heavily on the use of shelters and spend much of their time dwelling there. Often times these shelters are in rocky areas in Navajo Sandstone and basaltic lava flows. Gila monsters depend on water resources and can be observed in puddles of water after a summer rain. They avoid living in open areas, such as flats and open grasslands. Gila monsters spend 90% of their lifetime underground in burrows or rocky shelters. They are active in

1339-460: A half hours. There is only a single record of attempted mating outside of a shelter. The female lays eggs at the end of May into June. A clutch may consist of up to eight (rarely more than six) eggs. The incubation in captivity lasts about 5 months, depending on the incubation temperature. The hatchlings are about 16 cm (6.3 in) long and can bite and inject venom as soon as they are hatched. The egg development and hatching time of young in

1442-408: A population of 3,104,614 at the 2020 U.S. census . In 2022, the estimated population of Nevada was 3,177,772, an increase of 73,158 residents (2.36%) since the 2020 census . Nevada had the highest percentage growth in population from 2017 to 2018. At the 2020 census, 6.0% of the state's population were reported as under 5, 22.5% were under 18, and 16.1% were 65 or older. Females made up about 49.8% of

1545-402: A sophisticated injection formula with sustained release of the drug, the lizard protein remains effective much longer than the human hormone. This helps diabetics keep their blood glucose levels under control for a week by a single injection. Exenatide also slows the emptying of the stomach and causes a decrease in appetite, contributing to weight loss. The antidiabetic exenatide (Byetta) from

1648-692: A state boundary at just over 400 miles (640 km). This line begins in Lake Tahoe nearly 4 miles (6.4 km) offshore (in the direction of the boundary), and continues to the Colorado River where the Nevada, California, and Arizona boundaries merge 12 miles (19 km) southwest of the Laughlin Bridge. The largest mountain range in the southern portion of the state is the Spring Mountain Range , just west of Las Vegas. The state's lowest point

1751-536: A stout snout, massive head, and "little"-appearing eyes, which can be protected by a nictitating membrane . The Gila monster has four close living relatives, all of which are beaded lizards. There are three species in Mexico: Heloderma exasperatum , Heloderma horridum and Heloderma alvarezi , as well as another species in Guatemala: Heloderma charlesbogerti . The evolutionary history of

1854-448: A uniform, simple, and less colorful pattern. This drastically changes within the first 6 months of their lives. Hatchlings from the northern area of the species' distribution have a tendency to retain most of their juvenile pattern. It has also been seen that Gila monsters in areas with darker rocks and substrate will have darker colorations. The heads of males are very often larger and more triangular-shaped than in females. The length of

1957-423: A vote. The Nevadan pronunciation is the one used by the state legislature. At one time, the state's official tourism organization, TravelNevada, stylized the name of the state as "Nevăda", with a breve over the a indicating the locally preferred pronunciation, which was also available as a license plate design until 2007. Before the arrival of Europeans, the earliest inhabitants were Indigenous tribes including

2060-574: Is a landlocked state in the Western region of the United States . It borders Oregon to the northwest, Idaho to the northeast, California to the west, Arizona to the southeast, and Utah to the east. Nevada is the seventh-most extensive , the 32nd-most populous , and the ninth-least densely populated U.S. state. Nearly three-quarters of Nevada's population live in Clark County , which contains

2163-549: Is a species of venomous lizard native to the Southwestern United States and the northwestern Mexican state of Sonora . It is a heavy, slow-moving reptile, up to 56 centimetres (22 in) long, and it is the only venomous lizard native to the United States. Its venomous close relatives, the four beaded lizards (all former subspecies of Heloderma horridum ) inhabit Mexico and Guatemala . The Gila monster

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2266-606: Is almost entirely within the Basin and Range Province and is broken up by many north–south mountain ranges. Most of these ranges have endorheic valleys between them. Much of the northern part of the state is within the Great Basin , a mild desert that experiences hot temperatures in the summer and cold temperatures in the winter. Occasionally, moisture from the Arizona Monsoon will cause summer thunderstorms; Pacific storms may blanket

2369-467: Is along the Colorado River, south of Laughlin. Nevada has 172 mountain summits with 2,000 feet (610 m) of prominence. Nevada ranks second, after Alaska, for the greatest number of mountains in the United States, followed by California, Montana, and Washington. Nevada is the driest state in the United States. It is made up of mostly desert and semi-arid climate regions, and, with the exception of

2472-540: Is commemorated by Nevada Historical Markers 57 and 58 in Lincoln and Nye counties. Eight days before the presidential election of 1864 , Nevada became the 36th state in the Union, despite lacking the minimum 60,000 residents that Congress typically required a potential state to have in order to become a state. At the time, Nevada's population was little more than 40,000. Governor Nye was frustrated that previous attempts to send

2575-488: Is known about the social behavior of Gila monster, but it has been observed engaging in male to male combat, in which the dominant male lies on top of the subordinate one and pins it with its front and hind limbs. While fighting, both lizards arch their bodies, pushing against each other and twisting around in an effort to gain the dominant position. A "wrestling match" ends when the pressure exerts their forces, although bouts may be repeated. These bouts are typically observed in

2678-400: Is mainly because homesteads were not permitted in large enough sizes to be viable in the arid conditions that prevail throughout desert Nevada. Instead, early settlers would homestead land surrounding a water source, and then graze livestock on the adjacent public land, which is useless for agriculture without access to water (this pattern of ranching still prevails). The COVID-19 pandemic

2781-454: Is not within the boundaries of any county). The tourism industry remains Nevada's largest employer, with mining continuing as a substantial sector of the economy: Nevada is the fourth-largest producer of gold in the world. Nevada is the driest state, and has been influenced by climate change , droughts in Nevada have been increasing in frequency and severity, putting a further strain on Nevada's water security . The name "Nevada" comes from

2884-442: Is officially a consolidated municipality, meaning it legally functions as both a city and a county. As of 1919, there were 17 counties in the state, ranging from 146 to 18,159 square miles (380 to 47,030 km ). Lake County , one of the original nine counties formed in 1861, was renamed Roop County in 1862. Part of the county became Lassen County, California , in 1864, resolving border uncertainty. In 1883, Washoe County annexed

2987-658: Is pigmented in black-blue colors, picks up scent molecules to be transferred to the opening of the Jacobson organ around the middle of the upper mouth cavern. Prey may be crushed to death if large, or eaten alive, most of the time head first, and helped down by muscular contractions and neck flexing. After food has been swallowed, the Gila monster may immediately resume tongue flicking and search behavior for identifying more prey such as eggs or young in nests. Gila monsters are able to climb trees, cacti , and even fairly straight, rough-surfaced walls. "I have never been called to attend

3090-518: Is sluggish in nature, so it is not generally dangerous and very rarely poses a real threat to humans. However, it has a fearsome reputation and is sometimes killed despite the species being protected by state law in Arizona . The name "Gila" refers to the Gila River Basin in the U.S. states of Arizona and New Mexico , where the Gila monster was once plentiful. Heloderma means "studded skin", from

3193-468: Is still very questionable. A more successful strategy would be, for example, if the new "settlers" were offered intensive education about this species (e.g., limited toxicity, lifestyle) with the aim of tolerating the reptile or even being proud of having this unique "roommate" in one's own neighborhood. In 1963, the San Diego Zoo became the first zoo to successfully breed Gila monsters in captivity. In

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3296-664: Is the second-most populous county of Nevada. Its county seat is Reno . Washoe County includes the Reno–Sparks metropolitan area . Lyon County is the third most populous county. It was one of the nine original counties created in 1861. It was named after Nathaniel Lyon , the first Union General to be killed in the Civil War . Its current county seat is Yerington . Its first county seat was established at Dayton on November 29, 1861. There are 68 designated wilderness areas in Nevada, protecting some 6,579,014 acres (2,662,433 ha) under

3399-422: Is true for animals relocated to appropriate habitats. Besides this, they also become more exposed to predators. Therefore, the process of simple relocation is "naïve" and potentially dangerous for both the relocated animals and existing populations and for the inhabitants of the region where the resettlement is taking place. If relocating the lizards further away, they might be totally disoriented, thus their survival

3502-523: The Ancient Greek words helos ( ἧλος ), "the head of a nail or stud", and derma ( δέρμα ), "skin". The species epithet suspectum comes from the describer, paleontologist Edward Drinker Cope . At first, this new specimen of Heloderma was misidentified and considered to be a northern variation of the beaded lizard already known to live in Mexico. He suspected that the lizard might be venomous due to

3605-733: The Goshute , Southern Paiute , Mohave , and Wašišiw ( Washoe people ). Francisco Garcés was the first European in the area. Nevada was annexed as a part of the Spanish Empire in the northwestern territory of New Spain . Administratively, the area of Nevada was part of the Commandancy General of the Provincias Internas in the Viceroyalty of New Spain. Nevada became a part of Alta California (Upper California) province in 1804 when

3708-801: The Humboldt Sink near Lovelock . Several rivers drain from the Sierra Nevada eastward, including the Walker , Truckee , and Carson rivers. All of these rivers are endorheic basins , ending in Walker Lake , Pyramid Lake , and the Carson Sink , respectively. However, not all of Nevada is within the Great Basin. Tributaries of the Snake River drain the far north, while the Colorado River , which also forms much of

3811-470: The IUCN . They are listed as "Apparently Secure" by NatureServe . In 1952, the Gila monster became the first venomous animal to be given legal protection. They are now protected in all states of their distribution. International trade in the species is regulated under Appendix II of CITES . "Possibly the greatest threat to the continued existence of helodermatids is the man-made destruction of their habitat as

3914-483: The Las Vegas Valley , the average summer diurnal temperature range approaches 40 °F (22 °C) in much of the state. While winters in northern Nevada are long and fairly cold, the winter season in the southern part of the state tends to be of short duration and mild. Most parts of Nevada receive scarce precipitation during the year. The most rain that falls in the state falls on the east and northeast slopes of

4017-486: The Las Vegas–Paradise metropolitan area , including three of the state's four largest incorporated cities. Nevada's capital is Carson City . Las Vegas is the largest city in the state. Nevada is officially known as the "Silver State" because of the importance of silver to its history and economy. It is also known as the "Battle Born State" because it campaigned during its relatively brief territorial status as

4120-526: The Nevada Territory (1861–1864), then quickly achieved statehood during the American Civil War (1861–1865), (the words "Battle Born" also appear on its state flag ); due to the 16th presidency of Abraham Lincoln (1809–1865, served 1861–1865). The federal Union benefited immensely economically translated into military necessity from the support of newly awarded statehood as the 36th state by

4223-503: The Sierra Nevada . The average annual rainfall per year is about 7 inches (180 mm); the wettest parts get around 40 inches (1,000 mm). Nevada's highest recorded temperature is 125 °F (52 °C) at Laughlin on June 29, 1994, and the lowest recorded temperature is −50 °F (−46 °C) at San Jacinto on January 8, 1937. Nevada's 125 °F (52 °C) reading is the third highest statewide record high temperature of

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4326-507: The Spanish language , referring to Nevada's small overlap with the Sierra Nevada mountain range on its western edge; however, the rest of Nevada is largely desert and semi-arid , much of it within the central Great Basin region. Areas south of the Great Basin are within the Mojave Desert shared with Southern California , while the high altitude of Lake Tahoe and the Sierra Nevada lie on

4429-694: The Utah Territory and New Mexico Territory , then the Nevada Territory (March 2, 1861; named for the Sierra Nevada ). The first discovery of a major U.S. deposit of silver ore occurred in Comstock Lode under Virginia City, Nevada , in 1859. On March 2, 1861, the Nevada Territory separated from the Utah Territory and adopted its current name, shortened from The Sierra Nevada (Spanish for "snow-covered mountain range"). The 1861 southern boundary

4532-567: The eggs of birds, lizards, snakes, and tortoises . Three to four extensive meals in spring are claimed to give them enough energy for a whole season. They can store fat in their tails and therefore do not need to eat often. Nevertheless, they feed whenever they come across suitable prey. Young Gila monsters can swallow up to 50% of their body weight in a single meal. Adults may eat up to one third of their body weight in one meal. The Gila monster uses its extremely acute sense of smell to locate prey. The strong, two-ended tipped tongue, which

4635-499: The quality , but not the length , of the latter pronunciation is closer to the Spanish pronunciation (Spanish /a/ is open central [ä] , whereas American English /ɑː/ varies from back [ɑː] to central [äː] ), it is not the pronunciation used by Nevadans. State Assemblyman Harry Mortenson proposed a bill to recognize the alternative pronunciation of Nevada, though the bill was not supported by most legislators and never received

4738-452: The small and large intestines . These bioactive peptides are able to bind to VIP receptors in many different human tissues. One of these, helodermin, has been shown to inhibit the growth of lung cancer . In February 2024, a Colorado man died after sustaining a 4 minute long bite from a pet Gila Monster. Autopsy reports determined cause of death to come from the animal bite/venom. The constituents of H. suspectum venom that have received

4841-686: The Californias were split. With the Mexican War of Independence won in 1821, the province of Alta California became a territory (state) of Mexico, with a small population. Jedediah Smith entered the Las Vegas Valley in 1827, Peter Skene Ogden traveled the Humboldt River in 1828, and in 1829 a merchant from Nuevo México named Antonio Armijo streamlined travel along the Old Spanish Trail . Chronicling Armijo's route his scout Raphael Rivera

4944-509: The Colorado River, essentially all of present-day Nevada south of the 37th parallel . The transfer was prompted by the discovery of gold in the area, and officials thought Nevada would be better able to oversee the expected population boom. This area includes most of what is now Clark County and the Las Vegas metropolitan area. Mining shaped Nevada's economy for many years (see Silver mining in Nevada ). When Mark Twain lived in Nevada during

5047-406: The Gila monster came to an abrupt and unexpected end on October 28, 2016, when a backhoe was digging at the outer walls of a house in a suburb of northern Tucson . The backhoe extracted a nest of a female Gila monster with five eggs in the process of hatching. The Gila monster is now known to hatch near the end of October and immediately proceed into hibernation without surfacing. They then appear on

5150-596: The Gila monster has a varied reputation. The Apache believed its breath could kill a man, and the Tohono O'Odham and the Pima believed it possessed a spiritual power that could cause sickness. In contrast, the Seri and the Yaqui believed the Gila monster's hide had healing properties. The Navajo/Dine believe the Gila monster was the first medicine man. The Gila monster starred as a monster in

5253-436: The Gila monster include that the animal's breath is toxic enough to kill humans, that it can spit venom like a spitting cobra , that it can leap several feet in the air to attack, and that the Gila monster did not have an anus and therefore expelled waste from its mouth, the source of its venom and "fetid breath" (perhaps stemming from the fact that its venom in fact has an intense, specific smell). Among Native American tribes,

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5356-621: The Helodermatidae may be traced back to the Cretaceous period (145 to 166 million years ago), when Gobiderma pulchrum and Estesia mongolensis were present. The genus Heloderma has existed since the Miocene , when H. texana lived. Fragments of osteoderms from the Gila monster have been found in Late Pleistocene (10,000 to 8,000 years ago) deposits near Las Vegas , Nevada . Because

5459-462: The Las Vegas area is situated, is within the Mojave Desert . The area receives less rain in the winter but is closer to the Arizona Monsoon in the summer. The terrain is also lower, mostly below 4,000 feet (1,200 m), creating conditions for hot summer days and cool to chilly winter nights. Nevada and California have by far the longest diagonal line (in respect to the cardinal directions) as

5562-419: The Spanish adjective nevada ( [neˈβaða] ), meaning "snow-covered" or "snowy". The state takes its name from the Nevada Territory , which in turn was named for the Sierra Nevada . Nevadans pronounce the second syllable with the "a" of "apple" ( / n ə ˈ v æ d ə / ) while some people from outside of the state pronounce it with the "a" of "palm" ( / n ə ˈ v ɑː d ə / ). Although

5665-565: The Union". Statehood was rushed to the date of October 31 to help ensure Abraham Lincoln 's reelection on November   8 and post-Civil War Republican dominance in Congress, as Nevada's mining-based economy tied it to the more industrialized Union . As it turned out, however, Lincoln and the Republicans won the election handily and did not need Nevada's help. Nevada is one of only two states to significantly expand its borders after admission to

5768-529: The Union, with the other being Missouri , which acquired additional territory in 1837 due to the Platte Purchase . In 1866 another part of the western Utah Territory was added to Nevada in the eastern part of the state, setting the current eastern boundary. Nevada achieved its current southern boundaries on January 18, 1867, when it absorbed the portion of Pah-Ute County in the Arizona Territory west of

5871-514: The area with snow. The state's highest recorded temperature was 125 °F (52 °C) in Laughlin (elevation of 605 feet or 184 meters) on June 29, 1994. The coldest recorded temperature was −52  °F (−47  °C ) set in San Jacinto in 1972, in the northeastern portion of the state. The Humboldt River crosses the state from east to west across the northern part of the state, draining into

5974-463: The beaded lizards from further south. The scales of the belly are free from osteoderms. Female Gila monsters go through a total shed lasting about 2 weeks before depositing their eggs. The dorsal part is often shed in one large piece. Adult males normally shed in smaller segments in August. The young seem to be in constant shed. Adults have more or less yellow to pink colors on a black surface. Hatchlings have

6077-413: The boundary with Arizona , drains much of southern Nevada. The mountain ranges, some of which have peaks above 13,000 feet (4,000 m), harbor lush forests high above desert plains, creating sky islands for endemic species. The valleys are often no lower in elevation than 3,000 feet (910 m), while some in central Nevada are above 6,000 feet (1,800 m). The southern third of the state, where

6180-749: The cloaca. One study investigating a population of Gila monsters in southwestern Utah noted that the lizard's activity peaked from late April to mid June. The average distance traveled during their bouts of activity was 210 metres (690 ft), but on occasion some lizards would travel distances greater than 1 kilometre (0.62 mi). During the Gila monster's active season of approximately 90 days, only ten days were spent active. Gila monsters are slow sprinters, but they have relatively high endurance and maximal aerobic capacity ( VO 2 max ) compared to other lizards. They are preyed upon by coyotes , badgers and raptors . Hatchlings are preyed on by snakes, such as kingsnakes ( Lampropeltis sp.). Among adaptations to

6283-409: The constitution via overland mail and by sea had failed by October 24, so on October 26 the full text was sent by telegraph at a cost of $ 4,303.27  – the most costly telegraph on file at the time for a single dispatch, equivalent to $ 83,831.36 in 2023. Finally, the response from Washington came on October 31, 1864: "the pain is over, the child is born, Nevada this day was admitted into

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6386-474: The creation of the Nevada Territory out of the western portion of the Utah Territory in 1861. Nevada became the 36th state on October 31, 1864, as the second of two states added to the Union during the Civil War (the first being West Virginia ). Nevada is known for its libertarian laws. In 1940, with a population of just over 110,000 people, Nevada was by far the least-populated state, with less than half

6489-555: The end of its lower jaws, unlike snakes, whose venom is produced in glands behind the eyes. The Gila monster lacks strong musculature in glands above the eyes; instead, in Heloderma , the venom is propelled from the gland via a tubing to the base of the lower teeth and then by capillary forces into two grooves of the tooth and then chewed into the victim. The teeth are tightly anchored to the jaw ( pleurodont ). Broken and regular replacement teeth have to wait every time to go into position in

6592-607: The fabric of Nevada's own cultural landscape. As a result of the Mexican–American War and the Treaty of Guadalupe Hidalgo , Mexico permanently lost Alta California in 1848. The new areas acquired by the United States continued to be administered as territories. As part of the Mexican Cession (1848) and the subsequent California Gold Rush that used Emigrant Trails through the area, the state's area evolved first as part of

6695-484: The federal government presented the $ 49   million construction contract for Boulder Dam (now Hoover Dam ). The Nevada Test Site , 65 miles (105 km) northwest of the city of Las Vegas, was founded on January 11, 1951, for the testing of nuclear weapons . The site consists of about 1,350 square miles (3,500 km ) of the desert and mountainous terrain. Nuclear testing at the Nevada Test Site began with

6798-472: The film The Giant Gila Monster (though the titular monster was actually portrayed by a Mexican beaded lizard). It played a minor role in the motion picture The Treasure of the Sierra Madre . In Brock Brower 's 1971 novel The Late Great Creature , fictional horror movie star Simon Moro is presented as famous for playing the reptilian werewolf -like Gila Man. The 2011 animated film Rango featured

6901-495: The first independent government of the First Mexican Empire ( Mexico ) in 1821. The westward expanding United States a quarter-century later annexed the area of the Mexican Cession in 1849 after its victory in the Mexican–American War (1846–1848), and it was incorporated into the U.S. as part of the newly-organized larger federal New Mexico Territory (1850–1863 split with Arizona Territory , then statehood 1912) in

7004-460: The first permanent settlement in what is now Nevada, called Mormon Station (now Genoa), in 1851. Additionally, in June 1855, William Bringhurst and 29 other Mormon missionaries built the first permanent structure, a 150-foot square adobe fort , northeast of downtown Las Vegas, converging on the Spanish and Mormon Roads . The fort remained under Salt Lake City 's control until the winter of 1858–1859, and

7107-421: The first phase of its reopening on May 9, 2020. Restaurants, retailers, outdoor malls, and hair salons were among the businesses allowed to reopen, but with precautions in place, such as limiting occupancy to 50 percent. A second phase went into effect on May 29, 2020. It allowed for the reopening of state parks and businesses such as bars, gyms, and movie theaters. Casinos began reopening on June 4, 2020. Nevada

7210-519: The grooves in the teeth. The Gila monster is the largest extant lizard species native to North America north of the Mexican border. Its snout-to-vent length ranges from 26 to 36 cm (10 to 14 in). The tail is about 20% of the body size, and the largest specimens may reach 51 to 56 cm (20 to 22 in) in total length. Body mass is typically in the range of 550 to 800 g (1.21 to 1.76 lb). They appear strong in their body structure with

7313-476: The helodermatids have remained relatively unchanged morphologically, they are occasionally regarded as living fossils . Although the Gila monster appears closely related to the monitor lizards (varanids) of Africa, Asia, and Australia, their wide geographical separation and distinct features indicate that Heloderma is better placed in a separate family. The scales of the head, back, and tail contain little pearl-shaped bones (osteoderms) similar to those found in

7416-603: The jurisdiction of the National Park Service , U.S. Forest Service , and Bureau of Land Management . The Nevada state parks comprise protected areas managed by the state of Nevada, including state parks , state historic sites , and state recreation areas . There are 24 state park units, including Van Sickle Bi-State Park which opened in July 2011 and is operated in partnership with the adjacent state of California . The United States Census Bureau determined Nevada had

7519-408: The land is developed for construction or to create more cultivable land." Gila monsters found in these situations and relocated – with best intentions – up to 1.2 km (0.75 mi)  away, return to where they were found within 2 months and at great effort. This is up to five times the normal energy use than if they had not been removed, which uses up their energy stores unnecessarily. The same

7622-406: The last two decades, experienced breeders have shared their knowledge and expertise to give advice to other herpetologists on overcoming the difficulties in Heloderma reproduction under human care. Though the Gila monster is venomous, it poses little threat to humans due to its sluggish nature. Nevertheless, it has a fearsome reputation and is often killed by humans. Myths that have formed about

7725-573: The latter has recently been split into several species. While the fossil record of this family may date back to as far as the Cretaceous with genera such as Primaderma and Paraderma of North America, the oldest definitive members of the Helodermatidae date to the Early Oligocene , with Lowesaurus matthewi from North America (Nebraska) and Eurheloderma gallicum from Europe (France). Gila monster The Gila monster ( Heloderma suspectum , / ˈ h iː l ə / HEE -lə )

7828-470: The lizard had foul or toxic breath and that its bite was fatal. The Tombstone Epitaph of Tombstone, Arizona , wrote about a Gila monster that a local person caught on May 14, 1881: This is a monster, and no baby at that, it being probably the largest specimen ever captured in Arizona. It is 27 inches long and weighs 35 lb. It was caught by H. C. Hiatt on the road between Tombstone and Grand Central Mill, and

7931-460: The lizard in water, pry the jaws open with a knife or stick, or physically yank the lizard free. While pulling the lizard directly increases risk of severe lacerations from the lizard's sharp teeth, it may also mitigate envenomation. Symptoms of the bite include excruciating pain, edema, and weakness associated with a rapid drop in blood pressure. YouTuber Coyote Peterson described the bite as "like hot lava coursing through your veins" and claimed it

8034-450: The management of type 2 diabetes. It is a synthetic blueprint of the protein exendin-4, isolated from the Gila monster's venom. In a 3-year study with people with type 2 diabetes, exenatide showed healthy sustained glucose levels. The effectiveness is because the lizard protein is 53% identical to glucagon-like peptide-1 analog (GLP-1), a hormone released from the human digestive tract that helps to regulate insulin and glucagon . Using

8137-449: The massive infusion of the monetary support it provided of nearly $ 400 million dollars in rich underground geological layers of veins of silver ore generated at the time by the 1859 discovery of the legendary Comstock Lode , mined beneath and around Virginia City up to about 1874 / 1920s ). It is also known as the " Sagebrush State", for the native plant of the same name; and as the " Sage-hen State". The state's name means "snowy" in

8240-475: The mating season. Males with greater strength and endurance are thought to enjoy greater reproductive success. Although the Gila monster has a low metabolism and one of the lowest lizard sprint speeds, it has one of the highest aerobic scope values (the increase in oxygen consumption from rest to maximum metabolic exertion) among lizards, allowing it to engage in intense aerobic activity for a sustained period of time. Gila monsters are listed as near threatened by

8343-530: The morning during the dry season (spring and early summer). The lizards move to different shelters every 4–5 days up to the beginning of the summer season. By doing so, they optimize for a suitable microhabitat. Later in the summer, they may be active on warm nights or after a thunderstorm . They maintain a surface body temperature of about 30 °C (86 °F). Close to 37 °C (99 °F), they are able to decrease their body temperature by up to 2 °C (3.6 °F) by an activated, limited evaporation via

8446-403: The most attention from researchers are the bioactive peptides, including helodermin, helospectin, exendin-3, and exendin-4. Exendin-4, which is specific for H. suspectum , has formed the basis of a class of medications for the treatment of type 2 diabetes , known as GLP-1 receptor agonists . In 2005, the U.S. Food and Drug Administration approved the drug exenatide (marketed as Byetta) for

8549-401: The next five days in bed, but he completely recovered. When Scientific American ran another ill-founded report on the lizard's ability to kill people, he wrote in reply and described his own studies and personal experience. He wrote that he knew several people who had been bitten by Gila monsters, but had not died from the bite. The Gila monster produces venom in modified salivary glands at

8652-578: The period described in Roughing It , mining had led to an industry of speculation and immense wealth. Both mining and population temporarily declined in the late 19th century. However, the rich silver strike at Tonopah in 1900, followed by strikes in Goldfield and Rhyolite , created a second mining boom in Nevada and Nevada's population. Unregulated gambling was commonplace in the early Nevada mining towns but

8755-431: The population of the next least-populous state, Wyoming . However, legalized gambling and lenient marriage and divorce laws transformed Nevada into a major tourist destination in the 20th century. Nevada is the only U.S. state where prostitution is legal, though it is illegal in its most populated regions – Clark County (Las Vegas), Washoe County (Reno) and Carson City (which, as an independent city,

8858-430: The population. 19.1% of the population was reported as foreign-born. Since the 2020 census, the population of Nevada had a natural increase of 2,374 (the net difference between 42,076 births and 39,702 deaths); and an increase due to net migration of 36,605 (of which 34,280 was due to domestic and 2,325 was due to international migration). The center of population of Nevada is in southern Nye County . In this county,

8961-531: The portion that remained in Nevada. In 1969, Ormsby County was dissolved and the Consolidated Municipality of Carson City was created by the Legislature in its place coterminous with the old boundaries of Ormsby County. Bullfrog County was formed in 1987 from part of Nye County. After the creation was declared unconstitutional, the county was abolished in 1989. Humboldt County was designated as

9064-480: The region Nevada (snowy) because of the snow which covered the mountains in winter, similar to the Sierra Nevada mountains in European Spain . The area formed from mostly Alta California (Upper California) to the west and to the east as part of Nuevo México ( New Mexico )'s colonial province and territory to the northern portion within the larger colonial era Viceroyalty of New Spain , which gained freedom as

9167-599: The route remained largely under the control of Salt Lake City and Santa Fe tradespersons. As such, these pioneers laid the foundation for the emergence of the initial settlements between the Sierra Nevadas and Mojave Desert and within the Las Vegas Valley. The enduring influence of New Mexico and Utah culture has since profoundly impacted Nevada's identity, manifesting through New Mexican cuisine and Mormon foodways or New Mexican and Mormon folk musics , into

9270-489: The southern portion. To the north of the newly acquired Mexican / Spanish lands was the similarly larger Utah Territory (1850–1896) along with the far-western new 31st state of California on the Pacific Ocean coast also in 1850. The discovery of mineral wealth at the Comstock Lode silver bonanza in 1859 led to a population boom similar to that of earlier California Gold Rush in 1848–1852, that became an impetus to

9373-551: The state of Utah made the Gila monster its official state reptile . In 2023, Australian band King Gizzard and the Lizard Wizard released a single titled " Gila Monster " from their album PetroDragonic Apocalypse , with the album's artwork featuring a Gila monster on its cover art and heavily within the album's concept narrative. Nevada Nevada ( / n ə ˈ v æ d ə , - v ɑː -/ nə- VAD -ə, -⁠ VAH - , Spanish: [neˈβaða] )

9476-536: The surface from May through June the following year when prey should be abundant. In summer, Gila monsters gradually spend less time on the surface to avoid the hottest part of the season; occasionally, they may be active at night. Females that have laid eggs are exhausted and thin, fighting for survival, and have to spend extra effort to "reconstitute". The brumation of Gila monsters begins in October. Gila monsters can live up to 40 years in captivity, though rarely. Little

9579-620: The tail of the two sexes is statistically very similar, so it does not help in differentiation of the sexes. Individuals with stout tail ends occur in both nature and under human breeding. The Gila monster is found in the Southwestern United States and Mexico, across a range including Sonora, Arizona, and parts of California , Nevada, Utah , and New Mexico. No records have been given from Baja California . They inhabit scrubland , succulent desert, and oak woodland, seeking shelter in burrows, thickets, and under rocks in locations with

9682-464: The unincorporated town of Pahrump , 60 miles (97 km) west of Las Vegas on the California state line, has grown very rapidly from 1980 to 2020. At the 2020 census, the town had 44,738 residents. Las Vegas grew from a gulch of 100 people in 1900 to 10,000 by 1950 to 100,000 by 1970, and was America's fastest-growing city and metropolitan area from 1960 to 2000. From about the 1940s until 2003, Nevada

9785-570: The venomous Gila monster is also an example of a medical value of venom peptides, targeting G protein-coupled receptors (GPCRs). The Gila monster emerges from brumation in early March. Gila monsters sexually mature at 4–5 years old. It mates in April and May. The male initiates courtship by flicking his tongue to search for the female's scent. If the female rejects his advances, she will bite him and chase him away. When successful, copulation has been observed in captivity to last from 15 minutes to two and

9888-457: The western edge. In 2020, 80.1% of the state's land was managed by various jurisdictions of the U.S. federal government , both civilian and military. Native Americans of mostly the Paiute , Shoshone , and Washoe tribes inhabited what is now Nevada. The first Europeans to explore the region were tho Spanish and explorers from their worldwide Spanish Empire in the 16th century . They called

9991-402: The wild has been a subject of ongoing speculation. The first model stated that youngsters hatch in fall and stay underground. The second theory postulated a nearly developed embryo remains inside the egg over winter and hatches in spring. Hatchlings (weight about 35 g (1.2 oz)) are observed at the end of April to early June. Discussions of the exact egg development and hatching cycle of

10094-410: Was "the worst pain [he] had ever experienced". It is generally regarded as the most painful venom produced by any vertebrate. More than a dozen peptides and other substances have been isolated from the Gila monster's venom, including hyaluronidase , serotonin , phospholipase A 2 , and several kallikrein -like glycoproteins responsible for the pain and edema caused by a bite, without producing

10197-641: Was among the first to research the actual effects of Gila monster venom. Scientific American reported in 1890, "The breath is very fetid, and its odor can be detected at some little distance from the lizard. It is supposed that this is one way in which the monster catches the insects and small animals which form a part of its food supply – the foul gas overcoming them." Goodfellow offered to pay local residents $ 5.00 for Gila monster specimens. He bought several and collected more on his own. In 1891, he purposely provoked one of his captive lizards into biting him on his finger. The bite made him ill and he spent

10300-477: Was confirmed in Nevada on March 5, 2020. Because of concerns about coronavirus disease 2019 (COVID-19), Nevada governor Steve Sisolak declared a state of emergency on March 12, 2020. Four days later, Nevada reported its first death. On March 17, 2020, Sisolak ordered the closure of non-essential businesses in the state to help prevent the spread of the coronavirus. Various protests were held against Sisolak's shutdown order beginning in April 2020. Nevada launched

10403-483: Was outlawed in 1909 as part of a nationwide anti-gambling crusade. Because of subsequent declines in mining output and the decline of the agricultural sector during the Great Depression , Nevada again legalized gambling on March 19, 1931, with approval from the legislature. Governor Fred B. Balzar 's signature enacted the most liberal divorce laws in the country and open gambling. The reforms came just eight days after

10506-493: Was purchased by Messrs. Ed Baker and Charles Eastman, who now have it on exhibition at Kelley's Wine House, next door above Grand Hotel, Allen Street. Eastern people who have never seen one of these monsters should not fail to inspect his Aztecship, for they might accidentally stumble upon one some fine day and get badly frightened, except they know what it is. On May 8, 1890, southeast of Tucson , Arizona Territory , Empire Ranch owner Walter Vail captured and thought he had killed

10609-556: Was the first to name Las Vegas, in an 1830 report to governor José Antonio Chaves . Following the suggestions by Rivera of a spring, on the published expedition's map, located in the Las Vegas area John C. Frémont set up camp in Las Vegas Springs in 1844. In 1847, Mormons established the State of Deseret , claiming all of Nevada within the Great Basin and the Colorado watershed. They built

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