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74-611: The HVTN is the only HIV vaccine research network sponsored by the American government. It also manages the only large-scale HIV vaccine research trial network in Africa. The HVTN collaborates with the Division of Acquired Immunodeficiency Syndrome (DAIDS). Funding comes from the National Institute of Allergy and Infectious Diseases and National Institutes of Health , which oversee DAIDS. HVTN

148-410: A research question is identified. A gap in the current literature, as identified by a researcher, then engenders a research question. The research question may be parallel to the hypothesis . The hypothesis is the supposition to be tested. The researcher(s) collects data to test the hypothesis. The researcher(s) then analyzes and interprets the data via a variety of statistical methods, engaging in what

222-564: A "public domain", that of "humanity". This idea gained prevalence as a result of Western colonial history and ignores alternative conceptions of knowledge circulation. For instance, most indigenous communities consider that access to certain information proper to the group should be determined by relationships. There is alleged to be a double standard in the Western knowledge system. On the one hand, "digital right management" used to restrict access to personal information on social networking platforms

296-485: A dramatic impact on HIV mortality in this country. Nonetheless, treatment failures occur as a result of the development of resistance and/or noncompliance with complicated and often toxic regimens. Moreover, damage to the immune system is incompletely reversed. Thus, there is an ongoing, urgent need for new therapeutic agents and new ways to boost the immunity and rebuild and replace immunity lost to HIV infection. In addition, strategies to address critical questions regarding

370-504: A dramatic impact on our understanding of the pathogenesis and clinical management of HIV infection over the last decade. Studies conducted by DAIDS-funded clinical trials research networks have: More recent studies have shown that highly active antiretroviral therapy-regimens including reverse transcriptase and potent protease inhibitors -are capable of suppressing HIV viral load to undetectable levels in many infected individuals and partially restoring immune function. Such regimens have had

444-467: A non-empirical task is the prototyping of a new drug using a differentiated application of existing knowledge; another is the development of a business process in the form of a flow chart and texts where all the ingredients are from established knowledge. Much of cosmological research is theoretical in nature. Mathematics research does not rely on externally available data; rather, it seeks to prove theorems about mathematical objects . Research ethics

518-408: A novel interpretation of previous results. In analytical work, there are typically some new (for example) mathematical results produced or a new way of approaching an existing problem. In some subjects which do not typically carry out experimentation or analysis of this kind, the originality is in the particular way existing understanding is changed or re-interpreted based on the outcome of the work of

592-446: A number of approaches beginning with basic research on the structure and function of viral and cellular proteins critical to the virus life cycle. In order to foster drug development of new HIV therapies, DAIDS supports research on potential new cellular and viral therapeutic targets and new approaches to validate targets; molecules that could effectively block HIV replication; improved formulation of existing agents; approaches to restore

666-769: A potent anti-HIV immune response. Studies in animal models are aimed at defining how a vaccine could protect the host. For now, clinical evaluations in humans provide the only way of determining whether a vaccine candidate could trigger a safe and effective anti-HIV response in people. NIAID also supports comprehensive research on other biomedical/behavioral prevention approaches, including drugs and/or vaccines that prevent mother to infant HIV transmission, including during breastfeeding, microbicides for preventing sexual transmission of HIV, interventions that reduce behaviors that expose people to HIV, programs to reduce intravenous drug abuse, measures to control other sexually transmitted diseases (STDs), and antiretroviral therapies that may reduce

740-468: A research approach. Neither one is less effective than the other since they have their particular purpose in science. Typically empirical research produces observations that need to be explained; then theoretical research tries to explain them, and in so doing generates empirically testable hypotheses; these hypotheses are then tested empirically, giving more observations that may need further explanation; and so on. See Scientific method . A simple example of

814-493: A single, all-encompassing definition that is embraced by all who engage in it. Research, in its simplest terms, is searching for knowledge and searching for truth. In a formal sense, it is a systematic study of a problem attacked by a deliberately chosen strategy, which starts with choosing an approach to preparing a blueprint (design) and acting upon it in terms of designing research hypotheses, choosing methods and techniques, selecting or developing data collection tools, processing

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888-455: A variety of approaches, such as queer theory or feminist theory. Artistic research , also seen as 'practice-based research', can take form when creative works are considered both the research and the object of research itself. It is the debatable body of thought which offers an alternative to purely scientific methods in research in its search for knowledge and truth. The controversial trend of artistic teaching becoming more academics-oriented

962-418: Is " creative and systematic work undertaken to increase the stock of knowledge ". It involves the collection, organization, and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error . These activities are characterized by accounting and controlling for biases. A research project may be an expansion of past work in

1036-521: Is a discipline within the study of applied ethics . Its scope ranges from general scientific integrity and misconduct to the treatment of human and animal subjects. The social responsibilities of scientists and researchers are not traditionally included and are less well defined. The discipline is most developed in medical research . Beyond the issues of falsification, fabrication, and plagiarism that arise in every scientific field, research design in human subject research and animal testing are

1110-462: Is an approach that involves the development of theory as opposed to using observation and experimentation. As such, non-empirical research seeks solutions to problems using existing knowledge as its source. This, however, does not mean that new ideas and innovations cannot be found within the pool of existing and established knowledge. Non-empirical research is not an absolute alternative to empirical research because they may be used together to strengthen

1184-457: Is an important function of DAIDS. By surveying developments in key scientific areas, DAIDS assesses ongoing needs in biomedical research as well as requirements for outreach activities and for training scientific investigators. As part of this process, DAIDS works with advisory groups and community and health professional organizations, evaluating and redirecting program emphases to respond to changing research needs. Researcher Research

1258-590: Is becoming more common. This method has benefits that using one method alone cannot offer. For example, a researcher may choose to conduct a qualitative study and follow it up with a quantitative study to gain additional insights. Big data has brought big impacts on research methods so that now many researchers do not put much effort into data collection; furthermore, methods to analyze easily available huge amounts of data have also been developed. Types of Research Method 1. Observatory Research Method 2. Correlation Research Method Non-empirical ( theoretical ) research

1332-408: Is data collected specifically for the research, such as through interviews or questionnaires. Secondary data is data that already exists, such as census data, which can be re-used for the research. It is good ethical research practice to use secondary data wherever possible. Mixed-method research, i.e. research that includes qualitative and quantitative elements, using both primary and secondary data,

1406-612: Is headquartered at the Fred Hutchinson Cancer Research Center in Seattle . The vaccines being tested come from various producers, both commercial and non-profit. Typically, researchers conduct clinical research on human subjects by asking volunteers to give informed consent to participate in an experiment by taking drugs that have not always been proven safe or effective in humans, though their safety has been tested (usually in animals) prior to any human trials. At

1480-415: Is known as empirical research . The results of the data analysis in rejecting or failing to reject the null hypothesis are then reported and evaluated. At the end, the researcher may discuss avenues for further research . However, some researchers advocate for the reverse approach: starting with articulating findings and discussion of them, moving "up" to identification of a research problem that emerges in

1554-583: Is known as meta-research . A researcher is a person who conducts research, especially in order to discover new information or to reach a new understanding. In order to be a social researcher or a social scientist , one should have enormous knowledge of subjects related to social science that they are specialized in. Similarly, in order to be a natural science researcher, the person should have knowledge of fields related to natural science ( physics , chemistry , biology , astronomy , zoology and so on). Professional associations provide one pathway to mature in

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1628-454: Is leading to artistic research being accepted as the primary mode of enquiry in art as in the case of other disciplines. One of the characteristics of artistic research is that it must accept subjectivity as opposed to the classical scientific methods. As such, it is similar to the social sciences in using qualitative research and intersubjectivity as tools to apply measurement and critical analysis. Artistic research has been defined by

1702-460: Is not feasible, the researcher may collect data on participant and situational characteristics to statistically control for their influence on the dependent, or outcome, variable. If the intent is to generalize from the research participants to a larger population, the researcher will employ probability sampling to select participants. In either qualitative or quantitative research, the researcher(s) may collect primary or secondary data. Primary data

1776-946: Is often biased in the languages that are preferred ( linguicism ) and the geographic locations where research occurs. Periphery scholars face the challenges of exclusion and linguicism in research and academic publication. As the great majority of mainstream academic journals are written in English, multilingual periphery scholars often must translate their work to be accepted to elite Western-dominated journals. Multilingual scholars' influences from their native communicative styles can be assumed to be incompetence instead of difference. For comparative politics, Western countries are over-represented in single-country studies, with heavy emphasis on Western Europe, Canada, Australia, and New Zealand. Since 2000, Latin American countries have become more popular in single-country studies. In contrast, countries in Oceania and

1850-511: Is only when a range of tests are consistent over many kinds of data, researchers, and methods can one have confidence in the results." Plato in Meno talks about an inherent difficulty, if not a paradox, of doing research that can be paraphrased in the following way, "If you know what you're searching for, why do you search for it?! [i.e., you have already found it] If you don't know what you're searching for, what are you searching for?!" The goal of

1924-736: Is very powerful strategy for demonstrating methodology to health professions education as well as best suited for exploring challenging problems in health professions educations. In addition, PMP researcher Mandy Sha argued that a project management approach is necessary to control the scope, schedule, and cost related to qualitative research design, participant recruitment, data collection, reporting, as well as stakeholder engagement . The quantitative data collection methods rely on random sampling and structured data collection instruments that fit diverse experiences into predetermined response categories. These methods produce results that can be summarized, compared, and generalized to larger populations if

1998-482: The Caribbean are the focus of very few studies. Patterns of geographic bias also show a relationship with linguicism: countries whose official languages are French or Arabic are far less likely to be the focus of single-country studies than countries with different official languages. Within Africa, English-speaking countries are more represented than other countries. Generalization is the process of more broadly applying

2072-863: The European League of Institutes of the Arts launched The Florence Principles' on the Doctorate in the Arts . The Florence Principles relating to the Salzburg Principles and the Salzburg Recommendations of the European University Association name seven points of attention to specify the Doctorate / PhD in the Arts compared to a scientific doctorate / PhD. The Florence Principles have been endorsed and are supported also by AEC , CILECT , CUMULUS and SAR . The historical method comprises

2146-506: The School of Dance and Circus (Dans och Cirkushögskolan, DOCH), Stockholm in the following manner – "Artistic research is to investigate and test with the purpose of gaining knowledge within and for our artistic disciplines. It is based on artistic practices, methods, and criticality. Through presented documentation, the insights gained shall be placed in a context." Artistic research aims to enhance knowledge and understanding with presentation of

2220-451: The researcher . The degree of originality of the research is among the major criteria for articles to be published in academic journals and usually established by means of peer review . Graduate students are commonly required to perform original research as part of a dissertation . Scientific research is a systematic way of gathering data and harnessing curiosity . This research provides scientific information and theories for

2294-642: The scientific lacuna in culturally sensitive methods of data collection. Western methods of data collection may not be the most accurate or relevant for research on non-Western societies. For example, " Hua Oranga " was created as a criterion for psychological evaluation in Māori populations, and is based on dimensions of mental health important to the Māori people – "taha wairua (the spiritual dimension), taha hinengaro (the mental dimension), taha tinana (the physical dimension), and taha whanau (the family dimension)". Research

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2368-525: The 1978 Belmont Report . Today, research ethics committees , such as those of the US , UK , and EU , govern and oversee the responsible conduct of research. Meta-research is the study of research through the use of research methods. Also known as "research on research", it aims to reduce waste and increase the quality of research in all fields. Meta-research concerns itself with the detection of bias, methodological flaws, and other errors and inefficiencies. Among

2442-517: The HVTN simply could not educate people to the required level to make such a fast-moving, expensive, inherently non-commercial research project possible. Division of Acquired Immunodeficiency Syndrome The Division of Acquired Immunodeficiency Syndrome (DAIDS) is a division of the National Institute of Allergy and Infectious Diseases , which is part of the National Institutes of Health . It

2516-539: The HVTN, many current vaccine studies are using products with a safety record that has been established in previous human trials. The Nuremberg Code , the Declaration of Helsinki , and the Belmont Report are legal documents written in layman's terms which local governments use to model their laws for establishing rules for conducting clinical trials, and all contemporary clinical trials of international worth follow all

2590-458: The accuracy of observation of the time, the prediction will be verified. As the accuracy of observation improves with time, the hypothesis may no longer provide an accurate prediction. In this case, a new hypothesis will arise to challenge the old, and to the extent that the new hypothesis makes more accurate predictions than the old, the new will supplant it. Researchers can also use a null hypothesis, which states no relationship or difference between

2664-465: The areas that raise ethical questions most often. The list of historic cases includes many large-scale violations and crimes against humanity such as Nazi human experimentation and the Tuskegee syphilis experiment which led to international codes of research ethics. No approach has been universally accepted, but typically-cited codes are the 1947 Nuremberg Code , the 1964 Declaration of Helsinki , and

2738-756: The arts. A simpler understanding by Julian Klein defines artistic research as any kind of research employing the artistic mode of perception. For a survey of the central problematics of today's artistic research, see Giaco Schiesser . According to artist Hakan Topal , in artistic research, "perhaps more so than other disciplines, intuition is utilized as a method to identify a wide range of new and unexpected productive modalities". Most writers, whether of fiction or non-fiction books, also have to do research to support their creative work. This may be factual, historical, or background research. Background research could include, for example, geographical or procedural research. The Society for Artistic Research (SAR) publishes

2812-501: The biology of HIV by studying the virus' life cycle, virus-host interactions, and mechanisms of disease progression and transmission. HIV pathogenesis research also supports studies of how the immune system responds to the virus. Knowledge gained from these studies enhances the ability of researchers to create new agents and vaccines to combat HIV infection. The Division supports a large portfolio of investigator-initiated grants that are pursuing research focused on, but not limited to,

2886-422: The data are collected using proper sampling and data collection strategies. Quantitative research is concerned with testing hypotheses derived from theory or being able to estimate the size of a phenomenon of interest. If the research question is about people, participants may be randomly assigned to different treatments (this is the only way that a quantitative study can be considered a true experiment). If this

2960-623: The data, interpretation, and ending with presenting solution(s) of the problem. Another definition of research is given by John W. Creswell , who states that "research is a process of steps used to collect and analyze information to increase our understanding of a topic or issue". It consists of three steps: pose a question, collect data to answer the question, and present an answer to the question. The Merriam-Webster Online Dictionary defines research more generally to also include studying already existing knowledge: "studious inquiry or examination; especially : investigation or experimentation aimed at

3034-665: The difference is that the IRB consists of a professional ethics committee and the CAB consists of any community member who wants to supervise the safety, ethics, efficacy, or any other aspect of the research. The researchers of the HVTN deemed the creation of the CAB necessary for HIV vaccine research when it has not been necessary for other clinical research because the HIV epidemic is especially urgent, new research techniques are available now that did not exist before recent major advances in genetic engineering ,

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3108-424: The discovery and interpretation of facts, revision of accepted theories or laws in the light of new facts, or practical application of such new or revised theories or laws". Original research , also called primary research , is research that is not exclusively based on a summary, review, or synthesis of earlier publications on the subject of research. This material is of a primary-source character. The purpose of

3182-559: The existence of multiple, persistent HIV reservoirs even with the use of highly active antiretroviral therapy (HAART). Despite these advances, questions still remain about the molecular interactions involved in the regulation of HIV expression and replication. More information is also needed about how the virus evades the immune system in order to identify additional targets against which therapeutic interventions and vaccines can be directed. Therapeutics for treating HIV-1 and its associated opportunistic infections (OIs) are discovered through

3256-425: The explanation of the nature and the properties of the world. It makes practical applications possible. Scientific research may be funded by public authorities, charitable organizations, and private organizations. Scientific research can be subdivided by discipline . Generally, research is understood to follow a certain structural process . Though the order may vary depending on the subject matter and researcher,

3330-730: The field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research ) are documentation , discovery , interpretation , and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies , which vary considerably both within and between humanities and sciences. There are several forms of research: scientific , humanities , artistic , economic, social , business, marketing , practitioner research , life, technological , etc. The scientific study of research practices

3404-460: The finding of meta-research is a low rates of reproducibility across a large number of fields. This widespread difficulty in reproducing research has been termed the " replication crisis ." In many disciplines, Western methods of conducting research are predominant. Researchers are overwhelmingly taught Western methods of data collection and study. The increasing participation of indigenous peoples as researchers has brought increased attention to

3478-400: The findings and literature review. The reverse approach is justified by the transactional nature of the research endeavor where research inquiry, research questions, research method, relevant research literature, and so on are not fully known until the findings have fully emerged and been interpreted. Rudolph Rummel says, "... no researcher should accept any one or two tests as definitive. It

3552-439: The following areas: mechanisms of viral entry and infection, including the role of co-receptors and other cellular accessory molecules; the structure, function, and mechanism of action of viral genes and proteins ; development of in vitro and ex vivo assays to monitor virus growth and immune responses against HIV, and animal models for research on the regulation and function of viral proteins and genetic regulatory sequences;

3626-461: The following concepts are part of most formal historical research: Research is often conducted using the hourglass model structure of research. The hourglass model starts with a broad spectrum for research, focusing in on the required information through the method of the project (like the neck of the hourglass), then expands the research in the form of discussion and results. The major steps in conducting research are: The steps generally represent

3700-414: The following steps are usually part of most formal research, both basic and applied: A common misconception is that a hypothesis will be proven (see, rather, null hypothesis ). Generally, a hypothesis is used to make predictions that can be tested by observing the outcome of an experiment. If the outcome is inconsistent with the hypothesis, then the hypothesis is rejected (see falsifiability ). However, if

3774-469: The humanities is historical research, which is embodied in historical method . Historians use primary sources and other evidence to systematically investigate a topic, and then to write histories in the form of accounts of the past. Other studies aim to merely examine the occurrence of behaviours in societies and communities, without particularly looking for reasons or motivations to explain these. These studies may be qualitative or quantitative, and can use

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3848-571: The immune system of HIV-infected individuals; molecular and genetic approaches to protect susceptible, uninfected cells; combination regimens that impede the emergence of viral resistance; and assays to measure restored immunity of HIV-infected individuals. The evaluation of new drugs and therapeutic agents in people is another critical aspect of therapeutic research. These clinical studies define which new agents are effective against HIV and its associated OIs and also clarify how best to use these drugs. DAIDS-sponsored therapeutics research has already had

3922-447: The immunological and virological events controlling primary infection; factors affecting latent reservoirs of HIV; and host factors that modulate viral infection and/or disease progression. The Division's basic research efforts have yielded significant scientific information about HIV. For example, in recent years, DAIDS-funded investigators have identified new structures for viral components of HIV, additional chemokine co-receptors, and

3996-426: The independent or dependent variables. Research in the humanities involves different methods such as for example hermeneutics and semiotics . Humanities scholars usually do not search for the ultimate correct answer to a question, but instead, explore the issues and details that surround it. Context is always important, and context can be social, historical, political, cultural, or ethnic. An example of research in

4070-404: The late 2000s. Peer review is a form of self-regulation by qualified members of a profession within the relevant field. Peer review methods are employed to maintain standards of quality, improve performance, and provide credibility. In academia, scholarly peer review is often used to determine an academic paper's suitability for publication. Usually, the peer review process involves experts in

4144-646: The long-term effects of antiretroviral therapy and the best approaches to medical management are being developed. The discovery and development of an HIV/AIDS vaccine for the prevention of HIV infection and AIDS is a high priority of the NIAID. Through a balanced HIV program that integrates both basic research and empiric testing of candidate vaccines, NIAID supports a broad spectrum of research and development on HIV/AIDS vaccines. Preclinical vaccine research and development examines new vaccine concepts or approaches and new ways to deliver HIV antigens to people and to safely induce

4218-536: The majority of new infections are occurring in the developing world, NIAID's vaccine and prevention research activities are conducted on a global scale. These research programs are designed to define global research priorities, ensure the clinical relevance of future vaccine and prevention strategies to human populations most in need, strengthen collaborations with local investigators worldwide, and support training and infrastructure development in developing countries. The coordination of this complex program of AIDS research

4292-480: The original research is to produce new knowledge rather than present the existing knowledge in a new form (e.g., summarized or classified). Original research can take various forms, depending on the discipline it pertains to. In experimental work, it typically involves direct or indirect observation of the researched subject(s), e.g., in the laboratory or in the field, documents the methodology , results, and conclusions of an experiment or set of experiments, or offers

4366-451: The outcome is consistent with the hypothesis, the experiment is said to support the hypothesis. This careful language is used because researchers recognize that alternative hypotheses may also be consistent with the observations. In this sense, a hypothesis can never be proven, but rather only supported by surviving rounds of scientific testing and, eventually, becoming widely thought of as true. A useful hypothesis allows prediction and within

4440-423: The overall process; however, they should be viewed as an ever-changing iterative process rather than a fixed set of steps. Most research begins with a general statement of the problem, or rather, the purpose for engaging in the study. The literature review identifies flaws or holes in previous research which provides justification for the study. Often, a literature review is conducted in a given subject area before

4514-456: The public is generally overly-willing to volunteer to receive experimental vaccines for this cause, and yet the educational infrastructure already in place to disseminate information about the inherent risk in participating in vaccine research is lacking in society. For too many reasons, there is no precedent for research of this sort on this scale, and without integrating educational programs about this research into existing community institutions,

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4588-446: The research process is to produce new knowledge or deepen understanding of a topic or issue. This process takes three main forms (although, as previously discussed, the boundaries between them may be obscure): There are two major types of empirical research design: qualitative research and quantitative research. Researchers choose qualitative or quantitative methods according to the nature of the research topic they want to investigate and

4662-558: The research profession. The word research is derived from the Middle French " recherche ", which means "to go about seeking", the term itself being derived from the Old French term "recerchier," a compound word from "re-" + "cerchier", or "sercher", meaning 'search'. The earliest recorded use of the term was in 1577. Research has been defined in a number of different ways, and while there are similarities, there does not appear to be

4736-697: The research questions they aim to answer: Qualitative research refers to much more subjective non-quantitative, use different methods of collecting data, analyzing data, interpreting data for meanings, definitions, characteristics, symbols metaphors of things. Qualitative research further classified into the following types: Ethnography: This research mainly focus on culture of group of people which includes share attributes, language, practices, structure, value, norms and material things, evaluate human lifestyle. Ethno: people, Grapho: to write, this disciple may include ethnic groups, ethno genesis, composition, resettlement and social welfare characteristics. Phenomenology : It

4810-414: The rules set by these precedents. However, HIV vaccine research requires more than just these protections, and because of this, from the inception of their research the HVTN has instituted a "community advisory board" (CAB) system in addition to the usual controls. The CAB is similar to an Institutional Review Board (IRB) in that the researchers facilitate the granting of public data to both entities, but

4884-439: The same elite status as those of North America and Europe, because limitations on the availability of resources including high-quality paper and sophisticated image-rendering software and printing tools render these publications less able to satisfy standards currently carrying formal or informal authority in the publishing industry. These limitations in turn result in the under-representation of scholars from periphery nations among

4958-452: The same field who are consulted by editors to give a review of the scholarly works produced by a colleague of theirs from an unbiased and impartial point of view, and this is usually done free of charge. The tradition of peer reviews being done for free has however brought many pitfalls which are also indicative of why most peer reviewers decline many invitations to review. It was observed that publications from periphery countries rarely rise to

5032-413: The set of publications holding prestige status relative to the quantity and quality of those scholars' research efforts, and this under-representation in turn results in disproportionately reduced acceptance of the results of their efforts as contributions to the body of knowledge available worldwide. The open access movement assumes that all information generally deemed useful should be free and belongs to

5106-553: The significance of latently infected resting T cells , immune responses induced by current vaccine candidates, and the impact of HIV and human leukocyte antigen diversity. In addition, the relevance of SIV / SHIV models and the utility of novel vaccine designs must be explored. With regard to prevention research, new microbicides need to be developed and tested and new regimens for preventing maternal-infant transmission during breastfeeding, which are effective and practical for developing countries, need to be explored. Lastly, because

5180-757: The spread of HIV from infected people to their partners. This comprehensive vaccine and prevention program has led to a number of significant scientific advances in vaccine and prevention research. In the past, NIAID supported researchers have improved antigenicity through modifications to the envelope protein, elucidated the envelope structure of HIV, advanced our understanding of the role of cellular responses in controlling HIV, developed improved assays for measuring cytotoxic T lymphocytes (CTLs), developed new and better animal models for testing candidate vaccines, and evaluated promising candidates in animal and clinical studies. In order to accelerate identification of effective vaccine candidates, future studies will need to address

5254-421: The techniques and guidelines by which historians use historical sources and other evidence to research and then to write history. There are various history guidelines that are commonly used by historians in their work, under the headings of external criticism, internal criticism, and synthesis. This includes lower criticism and sensual criticism. Though items may vary depending on the subject matter and researcher,

5328-626: The triannual Journal for Artistic Research ( JAR ), an international, online, open access , and peer-reviewed journal for the identification, publication, and dissemination of artistic research and its methodologies, from all arts disciplines and it runs the Research Catalogue (RC), a searchable, documentary database of artistic research, to which anyone can contribute. Patricia Leavy addresses eight arts-based research (ABR) genres: narrative inquiry, fiction-based research, poetry, music, dance, theatre, film, and visual art. In 2016,

5402-418: The valid results of one study. Studies with a narrow scope can result in a lack of generalizability, meaning that the results may not be applicable to other populations or regions. In comparative politics, this can result from using a single-country study, rather than a study design that uses data from multiple countries. Despite the issue of generalizability, single-country studies have risen in prevalence since

5476-822: Was formed in 1986 as a part of the initiative to address the national research needs created by the advent and spread of the HIV / AIDS epidemic. Specifically, the Division's mission is to increase basic knowledge of the pathogenesis, natural history, and transmission of HIV disease and to support research that promotes progress in its detection, treatment, and prevention. DAIDS accomplishes this through planning, implementing, managing, and evaluating programs in (1) fundamental basic research, (2) discovery and development of therapies for HIV infection and its complications, and (3) discovery and development of vaccines and other prevention strategies. HIV pathogenesis research increases our understanding of

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