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Dunedin Multidisciplinary Health and Development Study

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Leukoaraiosis is a particular abnormal change in appearance of white matter near the lateral ventricles . It is often seen in aged individuals, but sometimes in young adults. On MRI , leukoaraiosis changes appear as white matter hyperintensities (WMHs) in T2 FLAIR images. On CT scans , leukoaraiosis appears as hypodense periventricular white-matter lesions .

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60-724: The Dunedin Multidisciplinary Health and Development Study (also known as the Dunedin Study ) is a detailed study of human health, development and behaviour. Based at the University of Otago in New Zealand, the Dunedin Study has followed the lives of 1037 babies born between 1 April 1972 and 31 March 1973 at Dunedin 's former Queen Mary Maternity Centre since their birth. Teams of national and international collaborators work on

120-549: A comedy night, hypnotist plus bigger events at Forsyth Barr Stadium . Typically there is a Highlanders rugby game scheduled during the week. Local bars organise events also with a range of live music and promotional deals. Historically events have included the Cookathon and a Miss O-Week competition hosted by The Outback. The Cookathon was held by a local pub (the Cook) with the premise that your first drink costs you about $ 20 which gives you

180-431: A festival like event taking place at the stadium. 2012 Toga Party saw an unofficial world record. A clocktower race also occurs, in the style of Chariots of Fire . Students must race round the tower and attached building, beginning on the first chime of the clock at noon and completing before the chimes cease. Unlike Chariots of Fire , the task is possible with a couple of students completing each year. Student behaviour

240-558: A former politician due to his non-academic background and record as Finance Minister. Several alumni also withheld donations and funding to Otago University following Robertson's appointment. In mid May 2024, the Otago Daily Times reported that donations to the University's Foundation Trust had declined from NZ$ 12.25 million in 2022 to NZ$ 7.09m in 2023. University development and alumni relations office director Shelagh Murray attributed

300-711: A link between IQ and brain size; the correspondence of brain structure with poor mental state, cardiovascular fitness, lead exposure, difficult childhoods, childhood self-control, and cannabis use. They have also found that children experiencing social isolation between the ages of 5 and 11 were more likely to have poor cardiovascular health, and increased age-related cognitive decline compared to those who were not socially isolated. The Dunedin Study has also suggested that poor mental health can cause poor physical health, and increased rates of ageing. University of Otago The University of Otago ( Māori : Ōtākou Whakaihu Waka )

360-480: A new role, namely, leading the Division of External Engagement to attend to alumni relations and liaising with secondary schools, among other matters. In December 2020, eight graduation ceremonies scheduled for that month were disrupted following threats to carry out a firearms and explosives attack on students attending graduation ceremonies scheduled for 7 and 8 December. On 18 December, a 22-year-old woman appeared in

420-473: A regular injection of government funding, the university subsequently incurred more debt in 2023 due to its capital programme of refurbishing existing buildings and building new buildings. In response, students staged a protest against the proposed cuts. Otago University Students Association president Quintin Jane also called on Education Minister Jan Tinetti to increase funding for universities. In late May 2023,

480-602: A sizable number of second and higher year undergraduates, as well as occasionally a significant postgraduate population. While some teaching is normally undertaken at a college, this generally represents a small percentage of a resident's formal tuition. Most colleges actively seek to foster a sense of community and academic achievement amongst their members through, variously, intercollegiate competitions , communal dining, apartment groups, traditionalism, independent students' clubs, college events and internal sporting and cultural societies. The colleges are geographically spread over

540-508: A t-shirt, three meal vouchers and reduced price on drinks then you spend the rest of the day binge drinking and 'telephoning' the occasional jug with mates. Each year the first years are encouraged to attend the toga parade and party dressed in white sheets wrapped as togas. Retailers called for an end of the parade after property damage and disorder during the 2009 event. However, the OUSA took it upon themselves to reintroduce this tradition, with

600-563: Is a public research collegiate university based in Dunedin , Otago , New Zealand. Founded in 1869, Otago is New Zealand's oldest university and one of the oldest universities in Oceania . The university was created by a committee led by Thomas Burns , and officially established by an ordinance of the Otago Provincial Council in 1869. Between 1874 and 1961 the University of Otago

660-743: Is a list of vice-chancellors of the university: White matter hyperintensity The term "leukoaraiosis" was coined in 1986 by Hachinski , Potter, and Merskey as a descriptive term for rarefaction ("araiosis") of the white matter, showing up as decreased density on CT and increased signal intensity on T2/FLAIR sequences (white matter hyperintensities) performed as part of MRI brain scans. These white matter changes are also commonly referred to as periventricular white matter disease, or white matter hyperintensities (WMH), due to their bright white appearance on T2 MRI scans. Many patients can have leukoaraiosis without any associated clinical abnormality. However, underlying vascular mechanisms are suspected to be

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720-449: Is a major concern for both the university administration and Dunedin residents in general. Concerns over student behaviour prompted the university to introduce a Code of Conduct (CoC) which its students must abide by in 2007. The introduction of the CoC was accompanied by the establishment of the dedicated 'Campus Watch' security force to keep tabs on crime and anti-social behaviour on campus and in

780-540: Is consistently ranked in the top 1% of universities in the world. The university has also been rated 5-Stars Plus by QS Stars in the QS World University Rankings . This is the maximum rating achievable under the QS Stars System, which takes into account the quality of Otago's facilities, teaching, graduate employability, internationalisation, and inclusiveness. Besides having 5 subjects in the top 50 in

840-583: Is now based on the college site, and includes the college's campuses in Invercargill and Alexandra . Staff of the university's Faculty of Education relocated to the college site. A merger had been considered before, however the present talks progressed further, and more amicably, than previously. The University of Otago owns, or is in affiliation with, fourteen residential colleges , which provide food, accommodation, social and welfare services. Most of these cater primarily for first year students, though some have

900-662: Is part of the Information Services Building and has over 2000 study spaces, 130 computer terminals, and laptop connections at 500 desks. It has Te Aka a Tāwhaki, a collection of Māori resources, and the Special Collections consisting of about 9,000 books printed before 1801. In total, the Central Library has over 800,000 print and electronic materials relating to the arts and humanities, commerce, education, physical education, social sciences, and technology. It

960-692: Is the Otago equivalent of Freshers' Week . New students are most commonly known by their seniors as 'freshers' or simply as 'first-years'. O-week is organised by the Otago University Students' Association and involves competitions such as 'Fresher of the Year' whereby several students volunteer to carry out a series of tasks throughout the week before being voted to win. Other competitions include that of different faculties facing off with each other. The OUSA also organises events each night including various concerts,

1020-543: The Otago Daily Times reported that the university had declined to inform staff of its NZ$ 60 million budget shortfall in November 2022. In late June 2023, the Government announced a NZ$ 128 million funding injection for degree-level and postgraduate programmes for New Zealand universities and other tertiary institutions. In response, acting Vice-Chancellor Nicholson stated that the university would still proceed with job cuts since

1080-711: The Clocktower complex , a striking group of Gothic revival buildings at the heart of the campus. These buildings were inspired by the then-new main building at the University of Glasgow in Scotland. Otago was the first university in Australasia to permit women to take a law degree. Ethel Benjamin graduated LLB in 1897. Later that year she became the first woman in the British Empire to appear as counsel in court. The University of Otago helped train medical personnel as part of

1140-502: The Auckland District Court on charges of threatening harm to people or property. Court documents have described the threat as being of a "magnitude surpassing the 15 March Christchurch mosque massacres ." On 14 July 2021, the woman, who has interim name suppression, admitted to threatening to carry out a firearms and explosives attack against Otago students. Her lawyer applied for a discharge without conviction. On 12 May 2022,

1200-555: The Dunedin Study, including a team at Duke University in the United States. The research is constantly evolving to encompass research made possible by new technology and seeks to answer questions about how people's early years have an impact on mental and physical health as they age. The study is now in its fifth decade and has produced over 1300 publications and reports, many of which have influenced or helped inform policy makers in New Zealand and overseas; many of these can be found on

1260-588: The Dunedin Study. The original pool of study members was selected from children born at the Queen Mary Maternity Centre in Dunedin who were still living in the wider Otago region three years later. In early years the study was not well funded and the local community helped collect data. The study members include 535 males and 502 females, 1013 singletons and 12 sets of twins. At the age 38 assessment, only one-third of members still resided in Dunedin; most of

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1320-399: The Dunedin urban area: In mid October 2019, the University of Otago announced that it would be building a new 450-room residential college called Te Rangi Hiroa, which will replace the current Te Rangi Hiroa College along Cumberland Street. The new college is estimated to cost NZ$ 90 million and is located on the corner of Albany and Forth Streets near the Dunedin campus. In mid-March 2023,

1380-677: The Otago University Medical Corps. They supplied or trained most of the New Zealand Army 's doctors and dentists during the First World War . Professor Robert Jack made the first radio broadcast in New Zealand from the physics department on 17 November 1921. Queen Elizabeth II visited the university library with the Duke of Edinburgh on 18 March 1970. This was the first time the royals completed informal "walkabouts" to meet

1440-454: The cause of the imaging findings. Hypertension , smoking, diabetes , hyperhomocysteinemia , and heart diseases are all risk factors for leukoaraiosis. Leukoaraiosis has been reported to be an initial stage of Binswanger's disease but this evolution does not always happen. White matter hyperintensities can be caused by a variety of factors, including ischemia , micro- hemorrhages , gliosis , damage to small blood vessel walls, breaches of

1500-531: The coat of arms with the O-shaped symbol while two thirds voted to change the Māori name from Te Whare Wānanga o Otāgo to Ōtākou Whakaihu Waka ("A Place of Many Firsts"). The new logo will be rolled out from March 2024 over a 12-month period at a cost of NZ$ 1.3 million. Many Fellowships add to the diversity of the people associated with "Otago". They include: In 1998, the physics department gained some fame for making

1560-536: The country), fee increases were limited to 17%. Since 2004, the Otago University NORML club, led by Abe Gray , met weekly on the Otago campus to protest by smoking cannabis in defiance of New Zealand's cannabis laws. In 2008, several members were arrested and issued with trespass notices banning them from the Union Lawn. The following is a list of chancellors of the University of Otago. The following

1620-512: The current Māori name from Te Whare Wānanga o Otāgo to Ōtākou Whakaihu Waka ("A Place of Many Firsts"). Acting Vice-Chancellor Professor Helen Nicholson stated that the proposed logo and name change was intended to create a visual identity that reflected modern Aotearoa New Zealand. The university also launched a consultation process for staff, students and alumni that will conclude on 16 April 2023. On 17 March 2023, an Otago Daily Times survey found that 77% (1,908) of 2,479 respondents opposed

1680-511: The decline in donor funding to the ongoing impact of Covid-19 , the economic recession and the cost-of-living crisis on individuals and businesses. The University of Otago's main campus is in Dunedin, which hosts the Central Administration as well as its Health Sciences, Humanities, Business School, and Sciences divisions. The architectural grandeur and accompanying gardens of the main campus in Dunedin led to its being ranked as one of

1740-538: The first Bose–Einstein condensate in the Southern Hemisphere . The 2006 Government investigation into research quality (to serve as a basis for future funding) ranked Otago the top University in New Zealand overall, taking into account the quality of its staff and research produced. It was also ranked first in the categories of Clinical Medicine, Biomedical Science, Law, English Literature and Language, History and Earth Science. The Department of Philosophy received

1800-472: The funding would only come into effect from 2024 onwards. In March 2024, Grant Robertson was designated as the next Vice-Chancellor, commencing July 2024. This announcement was accompanied by a 'major' 'almost wholesale' replacement of the university leadership. While University Chancellor Stephen Higgs and the university council supported Robertson's appointment, there was mixed reception from donors. While some were supportive, several objected to appointing

1860-604: The health of family members (2003–2006); the Parenting Study which focuses on the Dunedin Study member and their first three-year-old child; and the Next Generation Study which involved the offspring of Dunedin Study members as they turned 15 and looked at the lifestyles, behaviours, attitudes, and health of today's teenagers. It aims to see how these have changed from when the original Study Members were 15 (in 1987–88). This means that information across three generations of

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1920-543: The highest score for any nominated academic unit. Otago had been ranked fourth in the 2004 assessment. In 2006, a report released by the Ministry of Research, Science and Technology found that Otago was the most research intensive university in New Zealand, with 40% of staff time devoted to research and development. Journal "Science" has recommended worldwide study of Otago's Biochemistry database " Transterm ", which has genomic data on 40,000 species. The University of Otago

1980-551: The history of New Zealand and the Pacific, with specific emphasis on the Otago and Southland regions. The Hocken Collections was established in 1910 when Dunedin philanthropist Thomas Hocken donated his entire private collection to the University of Otago. It currently houses over 8,000 linear metres of archives and manuscripts. It is currently situated at the site of the former Otago Co-operative Dairy Company factory on Anzac Avenue, east of

2040-524: The last 10 years of content, but does have over 150,000 volumes, the vast majority of which are in storage. There is seating for over 400. The Science Library is at the north end of the campus in the Science III building, with seating for approximately 500. The Hocken Collections is a research library, archive, and art gallery of national significance which is administered by the University of Otago. The library's specialist areas include items relating to

2100-633: The later findings. This study was awarded the 2016 Prime Minister's Science Prize . In 2022 it was awarded the Royal Society Te Apārangi's Rutherford Medal . The Dunedin Study has found that walking speed is related to small brain differences, that the speed of ageing of one's brain relates to their general speed of ageing, a link between the amount of white matter hyperintensities and a person's rate of cognitive decline, that there are differences in brain structure of people with and without antisocial behaviour in their teenage/young adult years,

2160-603: The local District Health Boards. The university's Southland Campus also has a library. The university is divided into four academic divisions: For external and marketing purposes, the Division of Commerce is known as the Otago Business School, as that is the term commonly used for its equivalent in North America. Historically, there were a number of schools and faculties, which have now been grouped with stand alone departments to form these divisions. In addition to

2220-473: The main campus. The Robertson Library is the university's education library and is jointly run by the University of Otago's College of Education and Otago Polytechnic , which is also located near the university's Dunedin campus. The Wellington Medical and Health Sciences Library and the Canterbury Medical Library provide services to University of Otago students and staff, and the staff of

2280-505: The nickname "Breather" in recent years. The university's graduation song, Gaudeamus igitur, iuvenes dum sumus ("Let us rejoice, while we are young"), acknowledges students will continue to live up to the challenge, if not always in the way intended. The university's student magazine, Critic , is New Zealand's longest running student magazine. The Otago Association 's plan for the European settlement of southern New Zealand, conceived under

2340-491: The principles of Edward Gibbon Wakefield in the 1840s, envisaged a university. Dunedin leaders Thomas Burns and James Macandrew urged the Otago Provincial Council during the 1860s to set aside a land endowment for an institute of higher education . An ordinance of the council established the university in 1869, giving it 100,000 acres (400 km ) of land and the power to grant degrees in Arts, Medicine, Law and Music. Burns

2400-405: The proposed logo change. The process was also criticised for costing about $ 700,000 whilst large numbers of academic staff were made redundant on the grounds of budgetary shortfalls. On 11 July 2023, the University council voted to proceed with the logo and alternate Māori name change following a consultation process with staff, students, and alumni. Three quarters of respondents voted to replace

2460-726: The public, and it was the first visit of Prince Charles (then 21 years old) and Princess Anne (19 years) to this country. In May 2010 the university joined the Matariki Network of Universities (MNU) together with Dartmouth College (US), Durham University (UK), Queen's University (Canada), University of Tübingen (Germany), University of Western Australia (Australia) and Uppsala University (Sweden). Beginning in 2015 university Vice-Chancellor Harlene Hayne and Pro-Vice-Chancellor Tony Ballantyne implemented cuts in academic and support staff which generated enduring controversy. In this context The New Zealand Herald characterised

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2520-416: The publications section of their website. The Dunedin Study was the idea of psychology student Phil Silva , who worked on a neonatology survey involving 250 children with learning and behavioural issues. He identified that 10% had significant problems that had previously been undiagnosed, a topic that he researched in his 1978 doctoral thesis. He realised that a larger sample size was needed; this resulted in

2580-414: The remainder lived elsewhere in New Zealand and Australia. Study members were assessed at age three, and then at ages 5, 7, 9, 11, 13, 15, 18, 21, 26, 32, 38, 45 and, most recently, at age 52 (2024–present). Silva directed the study until he retired from the role in 2000. Professor Richie Poulton was the study's director from 2000 to 2023, and was succeeded by Professor Moana Theodore . She first worked for

2640-560: The same families will be available. Great emphasis is placed on retention of study members. At the most recent (age 45) completed assessment, 94% of all living eligible study members, or 938 people, participated. This is unprecedented for a longitudinal study, with many others worldwide experiencing more than 40% drop-out rates. The resulting database has produced a wealth of information on many aspects of human health and development. As of 2015 over 1,200 papers, reports, book chapters and other publications have been produced using findings from

2700-717: The scale of the Undie riots. In 2012 there were 80 people treated by emergency services and 15 arrests by police after the Hyde Street party went out of control. Otago students are notable for protesting over contentious political issues in nearly every decade. In the 1960s students at Otago who were involved with the Progressive Youth Movement led protests against the Vietnam War . In the 1960s mixed flatting (males and females were prohibited from sharing housing up to that time)

2760-569: The student neighbourhoods nearby. Campus Watch reports directly to the university's Proctor. Riots took place in 2006, 2007, 2008 and 2009 related to events surrounding the Undie 500 car rally organised by students from Canterbury University. Other student social events during the year such as the Toga Parade and the Hyde Street Keg Race are also notable for attracting police attention, but not to

2820-523: The study as an assistant in 1998, and returned in 2010 to work with Poulton. During an assessment, study members are brought back to Dunedin from wherever in the world they live. They participate in a day of interviews, physical tests, dental examinations, blood tests, computer questionnaires, and surveys. Sub-studies of the Dunedin Study include the Family Health History Study which involved the parents of Dunedin Study members to find out about

2880-459: The study. The multidisciplinary aspect of the study has always been a central focus, with information ranging across: A book, From Child to Adult: Dunedin Multidisciplinary Health and Development Study , was published in 1996 and aimed at presenting the major findings in a form accessible to the non-specialist. It includes information up to the age-21 assessment. A more recent book, The Origins of You: How Childhood Shapes Later Life , covers many of

2940-537: The university unveiled a new proposed logo replacing the traditional coat of arms with a symbol and a new Māori name for the institution as part of its Vision 2040 strategy. The process was spearheaded by Tony Ballantyne and the university's Division of External Engagement. The proposed symbol is intended to symbolise the Otakou channel in Otago harbour while the coat of arms will be retained for ceremonial settings such as graduation events. The proposal also involves changing

3000-473: The university was considering laying off several hundred staff members including academics. This marked the first time since its founding in 1878 that the university has faced a major debt crisis. According to the Otago Daily Times , the university had only started borrowing in mid-December 2022, incurring a year-end debt of NZ$ 30 million. While the university was able to come out of debt in January 2023 following

3060-430: The university's 'climate' as one of top-down 'suppression and fear' for its employees. The Otago Daily Times reported on 'demoralised teachers and researchers' who were 'locked in pain and anger at what their institution had become' and later opined that 'the university desperately needs a reset'. In 2020 the University of Otago announced that Hayne would be leaving the university and that Ballantyne would be given

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3120-525: The usual university disciplines, the University of Otago Medical School (founded 1875) is one of only two medical schools in New Zealand (with component schools in Dunedin , Christchurch and Wellington ); and Otago is the only university in the country to offer training in Dentistry. Other professional schools and faculties not found in all New Zealand universities include Pharmacy, Physical Education, Physiotherapy, Medical Laboratory Science, and Surveying. It

3180-615: The woman was sentenced to five months community detention and nine months intensive supervision. According to the University Chancellor, the bomb threat and subsequent cancellation of eight graduation ceremonies caused the University NZ$ 1.3 million. In mid-April 2023, Otago University reported that it was facing a NZ$ 60 million deficit due to declining student enrollments and a shortfall in government funding. In response, Acting Vice-Chancellor Professor Helen Nicholson stated that

3240-735: The world's most beautiful university campuses by the British newspaper The Daily Telegraph and American online news website The Huffington Post . In addition, the university has four satellite campuses in Auckland , Wellington , Christchurch , and Invercargill . The University of Otago has nine libraries: six based in Dunedin on the main university campus, the education library in Southland, plus two medical libraries in Wellington and Christchurch. All libraries have wireless access. The Central Library

3300-450: The world, the University of Otago has 10 subjects ranked between 51st and 100th in QS World University Rankings . As well as having 15 subjects in the top 100 in the world, Otago has another 7 subjects in the top 101 to 150 band, and 6 subjects in the top 151 to 200 band. In 2015, the University of Otago became the first New Zealand university to have a course in a QS Top 10 list, being ranked 8th in Dentistry. 'O-Week' or Orientation Week

3360-426: Was a part of the federal University of New Zealand , and issued degrees in its name. Otago is known for its vibrant student life, particularly its flatting , which is often in old houses. Otago students have a long-standing tradition of naming their flats. The nickname for Otago students, "Scarfie," comes from the habit of wearing a scarf during the cold southern winters. The nickname "Scarfie" has morphed into

3420-634: Was also home to the School of Mines, until this was transferred to the University of Auckland in 1987. Theology is also offered, traditionally in conjunction with the School of Ministry, Knox College , and Holy Cross College, Mosgiel . There are also a number of service divisions including: The University of Otago and the Dunedin College of Education (a specialist teacher training institution) merged on 1 January 2007. The University of Otago College of Education

3480-507: Was contested in various creative ways by Otago students. On 28 September 1993 Otago students protested against a fee increase at the University Registry (Clocktower Building), which ended in a violent clash with police. In the lead up to the 1996 general election students trying to stop a 25% fee increase occupied the University Registry (Clocktower Building) for over a week (which was followed by similar occupations at campuses around

3540-648: Was designed by the American architecture firm Hardy Holzman Pfeiffer and opened in 2001, replacing what was previously a 1960s-era modernist building. The Robert Stout Law Library is the university's law library and is based in the Richardson Building. The Health Sciences Library is in the Sayers Building, opposite the main entrance to Dunedin Hospital . The Health Sciences Library book collection only includes

3600-622: Was named Chancellor but he did not live to see the university open on 5 July 1871. The university conferred just one degree, to Alexander Watt Williamson , before becoming an affiliated college of the federal University of New Zealand in 1874. With the dissolution of the University of New Zealand in 1961 and the passage of the University of Otago Amendment Act 1961, the university resumed its power to confer degrees. Originally operating from William Mason 's Post Office building on Princes Street , it relocated to Maxwell Bury 's Clocktower and Geology buildings in 1878 and 1879. This evolved into

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