106-523: Dorothy Mary Crowfoot Hodgkin OM FRS HonFRSC (née Crowfoot ; 12 May 1910 – 29 July 1994) was a Nobel Prize -winning English chemist who advanced the technique of X-ray crystallography to determine the structure of biomolecules , which became essential for structural biology . Among her most influential discoveries are the confirmation of the structure of penicillin as previously surmised by Edward Abraham and Ernst Boris Chain ; and mapping
212-521: A chapter she contributed to The Chemistry of Penicillin . By then she had been married for 12 years, given birth to three children and been elected a Fellow of the Royal Society (FRS). Thereafter she would publish as "Dorothy Crowfoot Hodgkin", and this was the name used by the Nobel Foundation in its award to her and the biography it included among other Nobel Prize recipients; it is also what
318-498: A clinic in Buxton for thermal baths and gold treatments. After some treatment, Hodgkin returned to the lab, where she struggled to use the main switch on the x-ray equipment due to the condition of her hands. She had to create a lever on her own in order to utilize the switch. Her condition would become progressively worse and debilitating over time, with deformities in both her hands and feet, and prolonged periods of pain. While Hodgkin spent
424-806: A distinguished family of archaeologists. Her parents were John Winter Crowfoot (1873–1959), working for the country's Ministry of Education, and his wife Grace Mary (née Hood) (1877–1957), known to friends and family as Molly. The family lived in Cairo during the winter months, returning to England each year to avoid the hotter part of the season in Egypt. In 1914, Hodgkin's mother left her (age 4) and her two younger sisters Joan (age 2) and Elisabeth (age 7 months) with their Crowfoot grandparents near Worthing , and returned to her husband in Egypt. They spent much of their childhood apart from their parents, yet they were supportive from afar. Her mother would encourage Dorothy to pursue
530-526: A faster pace. It is characterised by greater use of prepositions, and word order that is closer to modern Romance languages, for example, while grammatically retaining more or less the same formal rules as Classical Latin. Ultimately, Latin diverged into a distinct written form, where the commonly spoken form was perceived as a separate language, for instance early French or Italian dialects, that could be transcribed differently. It took some time for these to be viewed as wholly different from Latin however. After
636-718: A few in German , Dutch , Norwegian , Danish and Swedish . Latin is still spoken in Vatican City, a city-state situated in Rome that is the seat of the Catholic Church . The works of several hundred ancient authors who wrote in Latin have survived in whole or in part, in substantial works or in fragments to be analyzed in philology . They are in part the subject matter of the field of classics . Their works were published in manuscript form before
742-404: A few. Famous and well regarded writers included Petrarch, Erasmus, Salutati , Celtis , George Buchanan and Thomas More . Non fiction works were long produced in many subjects, including the sciences, law, philosophy, historiography and theology. Famous examples include Isaac Newton 's Principia . Latin was also used as a convenient medium for translations of important works first written in
848-587: A great deal of time in a wheelchair in her later years, she remained scientifically active in her career. In 1937, Dorothy Crowfoot married Thomas Lionel Hodgkin, an historian's son, who was then teaching an adult-education class in mining and industrial communities in the north of England after he resigned from the Colonial Office . He was an intermittent member of the Communist Party and later wrote several major works on African politics and history, becoming
954-460: A means to acknowledge "exceptionally meritorious service in Our Navy and Our Army, or who may have rendered exceptionally meritorious service towards the advancement of Art, Literature and Science". All modern aspects of the order were established under his direction, including the division for military figures. From the outset, prime ministers attempted to propose candidates or lobbied to influence
1060-548: A native language, Medieval Latin was used across Western and Catholic Europe during the Middle Ages as a working and literary language from the 9th century to the Renaissance , which then developed a classicizing form, called Renaissance Latin . This was the basis for Neo-Latin which evolved during the early modern period . In these periods Latin was used productively and generally taught to be written and spoken, at least until
1166-723: A neck ribbon (as a necklet ), while women wear theirs on a ribbon bow pinned to the left shoulder, and aides-de-camp may wear the insignia on their aiguillettes . Since 1991, the insignia must be returned upon the recipient's death. number appointment There have been no honorary members of the Order of Merit since the death of the last such member, Nelson Mandela , in December 2013. Secretary and Registrar : Robin Janvrin, Baron Janvrin GCB , GCVO , QSO , PC As
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#17329057936851272-574: A portrait of Dorothy Crowfoot Hodgkin in 1978. One sketch is in the collection of the Science History Institute and another at the Royal Society in London. The portrait was never finished. A portrait of Dorothy Hodgkin by Bryan Organ was commissioned by private subscription to become part of the collection of the Royal Society. Accepted by the president of the society on 25 March 1982, it
1378-414: A post which she held until 1977. In the 1940s, one of her students was Margaret Roberts (later Margaret Thatcher ) who, while Prime Minister , hung a portrait of Hodgkin in her office at Downing Street out of respect for her former teacher. Hodgkin was, however a life-long Labour Party supporter. In April 1953, together with Sydney Brenner , Jack Dunitz , Leslie Orgel , and Beryl M. Oughton, Hodgkin
1484-551: A result, the list has variants, as well as alternative names. In addition to the historical phases, Ecclesiastical Latin refers to the styles used by the writers of the Roman Catholic Church from late antiquity onward, as well as by Protestant scholars. The earliest known form of Latin is Old Latin, also called Archaic or Early Latin, which was spoken from the Roman Kingdom , traditionally founded in 753 BC, through
1590-407: A separate language, existing more or less in parallel with the literary or educated Latin, but this is now widely dismissed. The term 'Vulgar Latin' remains difficult to define, referring both to informal speech at any time within the history of Latin, and the kind of informal Latin that had begun to move away from the written language significantly in the post-Imperial period, that led ultimately to
1696-695: A small number of Latin services held in the Anglican church. These include an annual service in Oxford, delivered with a Latin sermon; a relic from the period when Latin was the normal spoken language of the university. In the Western world, many organizations, governments and schools use Latin for their mottos due to its association with formality, tradition, and the roots of Western culture . Canada's motto A mari usque ad mare ("from sea to sea") and most provincial mottos are also in Latin. The Canadian Victoria Cross
1802-429: A sort of informal language academy dedicated to maintaining and perpetuating educated speech. Philological analysis of Archaic Latin works, such as those of Plautus , which contain fragments of everyday speech, gives evidence of an informal register of the language, Vulgar Latin (termed sermo vulgi , "the speech of the masses", by Cicero ). Some linguists, particularly in the nineteenth century, believed this to be
1908-565: A spoken and written language by the scholarship by the Renaissance humanists . Petrarch and others began to change their usage of Latin as they explored the texts of the Classical Latin world. Skills of textual criticism evolved to create much more accurate versions of extant texts through the fifteenth and sixteenth centuries, and some important texts were rediscovered. Comprehensive versions of authors' works were published by Isaac Casaubon , Joseph Scaliger and others. Nevertheless, despite
2014-593: A steely determination to achieve her ends, whatever obstacles might stand in her way. She inspired devotion in her students and colleagues, even the most junior of whom knew her simply as Dorothy. Her structural studies of biologically important molecules set standards for a field that was very much in development during her work life. She made fundamental contributions to the understanding of how these molecules carry out their tasks in living system. Hodgkin's mentor Professor John Desmond Bernal greatly influenced her life: scientifically, politically, and personally. Bernal
2120-432: A strictly left-to-right script. During the late republic and into the first years of the empire, from about 75 BC to AD 200, a new Classical Latin arose, a conscious creation of the orators, poets, historians and other literate men, who wrote the great works of classical literature , which were taught in grammar and rhetoric schools. Today's instructional grammars trace their roots to such schools , which served as
2226-689: A vernacular, such as those of Descartes . Latin education underwent a process of reform to classicise written and spoken Latin. Schooling remained largely Latin medium until approximately 1700. Until the end of the 17th century, the majority of books and almost all diplomatic documents were written in Latin. Afterwards, most diplomatic documents were written in French (a Romance language ) and later native or other languages. Education methods gradually shifted towards written Latin, and eventually concentrating solely on reading skills. The decline of Latin education took several centuries and proceeded much more slowly than
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#17329057936852332-400: A well-known lecturer at Balliol College in Oxford. As his health was too poor for active military service, he continued working throughout World War II, returning to Oxford on the weekends, where his wife remained working on penicillin . The couple had three children: Luke (b. 1938. d. Oct. 2020), Elizabeth (b. 1941) and Toby (b. 1946). The oldest son, Luke, became a mathematics instructor at
2438-411: Is Veritas ("truth"). Veritas was the goddess of truth, a daughter of Saturn, and the mother of Virtue. Switzerland has adopted the country's Latin short name Helvetia on coins and stamps, since there is no room to use all of the nation's four official languages . For a similar reason, it adopted the international vehicle and internet code CH , which stands for Confoederatio Helvetica ,
2544-781: Is "Dorothy Crowfoot Hodgkin". In 2022, the Department of Biochemistry in Oxford renamed its much expanded building after Hodgkin, calling it the "Dorothy Crowfoot Hodgkin Building". Between the 1950s and the 1970s, Hodgkin established and maintained lasting contacts with scientists in her field abroad—at the Institute of Crystallography in Moscow ; in India; and with the Chinese group working in Beijing and Shanghai on
2650-626: Is a reversal of the original phrase Non terrae plus ultra ("No land further beyond", "No further!"). According to legend , this phrase was inscribed as a warning on the Pillars of Hercules , the rocks on both sides of the Strait of Gibraltar and the western end of the known, Mediterranean world. Charles adopted the motto following the discovery of the New World by Columbus, and it also has metaphorical suggestions of taking risks and striving for excellence. In
2756-548: Is found in any widespread language, the languages of Spain, France, Portugal, and Italy have retained a remarkable unity in phonological forms and developments, bolstered by the stabilising influence of their common Christian (Roman Catholic) culture. It was not until the Muslim conquest of Spain in 711, cutting off communications between the major Romance regions, that the languages began to diverge seriously. The spoken Latin that would later become Romanian diverged somewhat more from
2862-661: Is modelled after the British Victoria Cross which has the inscription "For Valour". Because Canada is officially bilingual, the Canadian medal has replaced the English inscription with the Latin Pro Valore . Spain's motto Plus ultra , meaning "even further", or figuratively "Further!", is also Latin in origin. It is taken from the personal motto of Charles V , Holy Roman Emperor and King of Spain (as Charles I), and
2968-958: Is taught at many high schools, especially in Europe and the Americas. It is most common in British public schools and grammar schools, the Italian liceo classico and liceo scientifico , the German Humanistisches Gymnasium and the Dutch gymnasium . Occasionally, some media outlets, targeting enthusiasts, broadcast in Latin. Notable examples include Radio Bremen in Germany, YLE radio in Finland (the Nuntii Latini broadcast from 1989 until it
3074-531: The Corpus Inscriptionum Latinarum (CIL). Authors and publishers vary, but the format is about the same: volumes detailing inscriptions with a critical apparatus stating the provenance and relevant information. The reading and interpretation of these inscriptions is the subject matter of the field of epigraphy . About 270,000 inscriptions are known. The Latin influence in English has been significant at all stages of its insular development. In
3180-605: The Battle of Trafalgar in 1805, First Lord of the Admiralty Charles Middleton, 1st Baron Barham and William Pitt exchanged correspondence concerning the possible creation of an order of merit, though nothing came of the idea. Later, Queen Victoria , her courtiers , and politicians alike, thought that a new order, based on the Prussian order Pour le Mérite , would make up for the insufficient recognition offered by
3286-562: The Holy See , the primary language of its public journal , the Acta Apostolicae Sedis , and the working language of the Roman Rota . Vatican City is also home to the world's only automatic teller machine that gives instructions in Latin. In the pontifical universities postgraduate courses of Canon law are taught in Latin, and papers are written in the same language. There are
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3392-747: The Indo-European languages . Latin was originally spoken by the Latins in Latium (now known as Lazio ), the lower Tiber area around Rome , Italy. Through the expansion of the Roman Republic it became the dominant language in the Italian Peninsula and subsequently throughout the Roman Empire . By the late Roman Republic , Old Latin had evolved into standardized Classical Latin . Vulgar Latin refers to
3498-557: The Lieutenant Governor of Nova Scotia , stated that the Order of Merit was the highest civilian award for merit a Canadian could receive. Some orders of precedence are as follows: Order of wear Latin Latin ( lingua Latina , pronounced [ˈlɪŋɡʷa ɫaˈtiːna] , or Latinum [ɫaˈtiːnʊ̃] ) is a classical language belonging to the Italic branch of
3604-561: The Middle Ages , borrowing from Latin occurred from ecclesiastical usage established by Saint Augustine of Canterbury in the 6th century or indirectly after the Norman Conquest , through the Anglo-Norman language . From the 16th to the 18th centuries, English writers cobbled together huge numbers of new words from Latin and Greek words, dubbed " inkhorn terms ", as if they had spilled from a pot of ink. Many of these words were used once by
3710-559: The Roman Rite of the Catholic Church at the Vatican City . The church continues to adapt concepts from modern languages to Ecclesiastical Latin of the Latin language. Contemporary Latin is more often studied to be read rather than spoken or actively used. Latin has greatly influenced the English language , along with a large number of others, and historically contributed many words to
3816-553: The Romance languages . During the Classical period, informal language was rarely written, so philologists have been left with only individual words and phrases cited by classical authors, inscriptions such as Curse tablets and those found as graffiti . In the Late Latin period, language changes reflecting spoken (non-classical) norms tend to be found in greater quantities in texts. As it
3922-575: The Royal Air Force and, in 1969, the definition of honorary recipients was expanded to include members of the Commonwealth of Nations that are not realms. The order has always been open to women, Florence Nightingale being the first woman to receive the honour, in 1907. Several individuals have refused admission into the Order of Merit, including Rudyard Kipling , A. E. Housman , and George Bernard Shaw . Prince Philip, Duke of Edinburgh , remains
4028-606: The Science History Institute calls her. For simplicity's sake, Hodgkin is referred to as "Dorothy Hodgkin" by the Royal Society, when referring to its sponsorship of the Dorothy Hodgkin fellowship, and by Somerville College, after it inaugurated the annual lectures in her honour. The National Archives of the United Kingdom refer to her as "Dorothy Mary Crowfoot Hodgkin"; on a variety of plaques commemorating places where she worked or lived, e.g. 94 Woodstock Road, Oxford , she
4134-622: The Western Roman Empire fell in 476 and Germanic kingdoms took its place, the Germanic people adopted Latin as a language more suitable for legal and other, more formal uses. While the written form of Latin was increasingly standardized into a fixed form, the spoken forms began to diverge more greatly. Currently, the five most widely spoken Romance languages by number of native speakers are Spanish , Portuguese , French , Italian , and Romanian . Despite dialectal variation, which
4240-493: The "Order of Minerva " with membership restricted to 24 distinguished artists and authors. Knights would be entitled to the post-nominal letters KM , and would wear a silver nine-pointed breast star with the image of Minerva at its centre, along with a "straw-coloured" sash worn across the chest from the right shoulder. The motto of the Order would be "Omnia posthabita scientiae" (in Latin , 'Everything comes after science'). Once
4346-477: The 1993 Congress, where she was welcomed by all. She died in July 1994 after a stroke, at her husband's home in the village of Ilmington , near Shipston-on-Stour , Warwickshire . The National Portrait Gallery, London lists 17 portraits of Dorothy Hodgkin including an oil painting of her at her desk by Maggi Hambling and a photograph portrait by David Montgomery . Graham Sutherland made preliminary sketches for
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4452-617: The British Crown. The motto is featured on all presently minted coinage and has been featured in most coinage throughout the nation's history. Several states of the United States have Latin mottos , such as: Many military organizations today have Latin mottos, such as: Some law governing bodies in the Philippines have Latin mottos, such as: Some colleges and universities have adopted Latin mottos, for example Harvard University 's motto
4558-599: The English lexicon , particularly after the Christianization of the Anglo-Saxons and the Norman Conquest . Latin and Ancient Greek roots are heavily used in English vocabulary in theology , the sciences , medicine , and law . A number of phases of the language have been recognized, each distinguished by subtle differences in vocabulary, usage, spelling, and syntax. There are no hard and fast rules of classification; different scholars emphasize different features. As
4664-580: The Grinch Stole Christmas! , The Cat in the Hat , and a book of fairy tales, " fabulae mirabiles ", are intended to garner popular interest in the language. Additional resources include phrasebooks and resources for rendering everyday phrases and concepts into Latin, such as Meissner's Latin Phrasebook . Some inscriptions have been published in an internationally agreed, monumental, multivolume series,
4770-517: The King's proposal was made public, however, arguments within intellectual circles over who would be most deserving of the new order grew so heated that George ultimately dropped the idea, though he briefly reconsidered it in 1789; on 6 February of that year, he revised the design of the order, with the breast star to have sixteen points, the motto to be the Latin for "Learning improves character" and with membership to include distinguished scientists. Following
4876-572: The Nature of Things ", which helped her decide her future. She was further encouraged by the chemist A.F. Joseph, a family friend who also worked in Sudan. Her state school education did not include Latin , then required for entrance to Oxbridge . Her Leman School headmaster, George Watson, gave her personal tuition in the subject, enabling her to pass the University of Oxford entrance examination. When Hodgkin
4982-520: The Order of Merit is open to the citizens of 15 countries, each with their own system of orders, decorations, and medals, the order's place of precedence varies from country to country. While, in the United Kingdom, the order's postnominal letters follow those of Knights and Dames Grand Cross of the Order of the Bath , membership in the Order of Merit itself gives members no place in any of the orders of precedence in
5088-425: The Order of Merit, members are entitled to use the post-nominal letters OM and are entrusted with the badge of the order. The insignia consists of a badge, which consists of a golden crown from which is suspended a red enamelled cross pattée , itself centred by a disk of blue enamel, surrounded by a laurel wreath . The obverse of the badge's central disk bears the words FOR MERIT in gold lettering, while
5194-432: The Royal Society (when referring to its sponsorship of the Dorothy Hodgkin fellowship), and by Somerville College. The National Archives of the United Kingdom refer to her as "Dorothy Mary Crowfoot Hodgkin". Dorothy Mary Crowfoot was born in Cairo , Egypt , the oldest of the four daughters whose parents worked in North Africa and the middle East in the colonial administration and later as archaeologists. Dorothy came from
5300-406: The United Kingdom . However, Stanley Martin says in his book The Order of Merit 1902–2002: One Hundred Years of Matchless Honour , that the Order of Merit is the pinnacle of the British honours system. Similarly, though it was not listed in the Canadian order of precedence for honours, decorations, and medals until December 2010, Christopher McCreery, an expert on Canadian honours and secretary to
5406-409: The United States the unofficial national motto until 1956 was E pluribus unum meaning "Out of many, one". The motto continues to be featured on the Great Seal . It also appears on the flags and seals of both houses of congress and the flags of the states of Michigan, North Dakota, New York, and Wisconsin. The motto's 13 letters symbolically represent the original Thirteen Colonies which revolted from
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#17329057936855512-447: The University of Kentucky, the University of Oxford and also Princeton University. There are many websites and forums maintained in Latin by enthusiasts. The Latin Misplaced Pages has more than 130,000 articles. Italian , French , Portuguese , Spanish , Romanian , Catalan , Romansh , Sardinian and other Romance languages are direct descendants of Latin. There are also many Latin borrowings in English and Albanian , as well as
5618-527: The archaeological site of Jerash , in present-day Jordan, where she documented the patterns of mosaics from multiple Byzantine-era Churches dated to the 5th–6th centuries. She spent more than a year finishing the drawings as she started her studies in Oxford, while also conducting chemical analyses of glass tesserae from the same site. Her attention to detail through the creation of precise scale drawings of these mosaics mirrors her subsequent work in recognising and documenting patterns in chemistry. Hodgkin enjoyed
5724-467: The autumn of that year, she began studying for a PhD at Newnham College, Cambridge , under the supervision of John Desmond Bernal . It was then that she became aware of the potential of X-ray crystallography to determine the structure of proteins . She was working with Bernal on the technique's first application to the analysis of a biological substance, pepsin . The pepsin experiment is largely credited to Hodgkin, however she always made it clear that it
5830-425: The benefit of those who do not understand Latin. There are also songs written with Latin lyrics . The libretto for the opera-oratorio Oedipus rex by Igor Stravinsky is in Latin. Parts of Carl Orff 's Carmina Burana are written in Latin. Enya has recorded several tracks with Latin lyrics. The continued instruction of Latin is seen by some as a highly valuable component of a liberal arts education. Latin
5936-409: The careful work of Petrarch, Politian and others, first the demand for manuscripts, and then the rush to bring works into print, led to the circulation of inaccurate copies for several centuries following. Neo-Latin literature was extensive and prolific, but less well known or understood today. Works covered poetry, prose stories and early novels, occasional pieces and collections of letters, to name
6042-503: The chemist Charles Harington (later Sir Charles), recommended D. S. Parsons' Fundamentals of Biochemistry . Resuming the pre-war pattern, her parents lived and worked abroad for part of the year, returning to England and their children for several months every summer. In 1926, on his retirement from the Sudan Civil Service, her father took the post of Director of the British School of Archaeology in Jerusalem, where he and her mother remained until 1935. In 1928, Hodgkin joined her parents at
6148-415: The classicised Latin that followed through to the present are often grouped together as Neo-Latin , or New Latin, which have in recent decades become a focus of renewed study , given their importance for the development of European culture, religion and science. The vast majority of written Latin belongs to this period, but its full extent is unknown. The Renaissance reinforced the position of Latin as
6254-412: The country's full Latin name. Some film and television in ancient settings, such as Sebastiane , The Passion of the Christ and Barbarians (2020 TV series) , have been made with dialogue in Latin. Occasionally, Latin dialogue is used because of its association with religion or philosophy, in such film/television series as The Exorcist and Lost (" Jughead "). Subtitles are usually shown for
6360-429: The decline in written Latin output. Despite having no native speakers, Latin is still used for a variety of purposes in the contemporary world. The largest organisation that retains Latin in official and quasi-official contexts is the Catholic Church . The Catholic Church required that Mass be carried out in Latin until the Second Vatican Council of 1962–1965 , which permitted the use of the vernacular . Latin remains
6466-405: The educated and official world, Latin continued without its natural spoken base. Moreover, this Latin spread into lands that had never spoken Latin, such as the Germanic and Slavic nations. It became useful for international communication between the member states of the Holy Roman Empire and its allies. Without the institutions of the Roman Empire that had supported its uniformity, Medieval Latin
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#17329057936856572-409: The established honours system to achievement outside public service, in fields such as art, music, literature, industry and science. Victoria's husband, Albert, Prince Consort , took an interest in the matter; it was recorded in his diary that he met Sir Robert Peel on 16 January 1844 to discuss the "idea of institution of a civil Order of Merit" and, three days later, he conferred with the Queen on
6678-399: The experience of field archaeology so much that she considered giving up chemistry in favour of archaeology. Her drawings are archived by Yale University. Hodgkin developed a passion for chemistry from a young age, and her mother, a proficient botanist, fostered her interest in the sciences. On her 16th birthday her mother gave her a book by W. H. Bragg on X-ray crystallography , " Concerning
6784-451: The first X-ray diffraction studies of pepsin and crystalline protein . Hodgkin always referred to him as "Sage". They were lovers before she met Thomas Hodgkin. The marriages of both Dorothy and Bernal were unconventional by the standards of the present and of those days. In 1934, at the age of 24, Dorothy began experiencing pain in her hands causing them to become swollen and distorted. She was diagnosed with rheumatoid arthritis, and went to
6890-403: The interest in crystals first displayed at the age of 10. In 1923, Dorothy and her sister would study pebbles that they had found in nearby streams using portable mineral analysis kit. Their parents then moved south to Sudan where, until 1926, her father was in charge of education and archaeology. Her mother's four brothers were killed in World War I and as a result she became an ardent supporter of
6996-504: The invention of printing and are now published in carefully annotated printed editions, such as the Loeb Classical Library , published by Harvard University Press , or the Oxford Classical Texts , published by Oxford University Press . Latin translations of modern literature such as: The Hobbit , Treasure Island , Robinson Crusoe , Paddington Bear , Winnie the Pooh , The Adventures of Tintin , Asterix , Harry Potter , Le Petit Prince , Max and Moritz , How
7102-412: The language of the Roman Rite . The Tridentine Mass (also known as the Extraordinary Form or Traditional Latin Mass) is celebrated in Latin. Although the Mass of Paul VI (also known as the Ordinary Form or the Novus Ordo) is usually celebrated in the local vernacular language, it can be and often is said in Latin, in part or in whole, especially at multilingual gatherings. It is the official language of
7208-440: The large areas where it had come to be natively spoken. However, even after the fall of Western Rome , Latin remained the common language of international communication , science, scholarship and academia in Europe until well into the early 19th century, by which time modern languages had supplanted it in common academic and political usage. Late Latin is the literary language from the 3rd century AD onward. No longer spoken as
7314-414: The last person so honoured. Honorary members form another group, to which there is no numerical limit, though such appointments are rare; individuals from countries in the Commonwealth of Nations that are not headed by King Charles are therefore considered foreigners, and thus are granted only honorary admissions, such as Nelson Mandela (South Africa) and Mother Teresa (India). Upon admission into
7420-412: The late seventeenth century, when spoken skills began to erode. It then became increasingly taught only to be read. Latin grammar is highly fusional , with classes of inflections for case , number , person , gender , tense , mood , voice , and aspect . The Latin alphabet is directly derived from the Etruscan and Greek alphabets . Latin remains the official language of the Holy See and
7526-431: The later part of the Roman Republic , up to 75 BC, i.e. before the age of Classical Latin . It is attested both in inscriptions and in some of the earliest extant Latin literary works, such as the comedies of Plautus and Terence . The Latin alphabet was devised from the Etruscan alphabet . The writing later changed from what was initially either a right-to-left or a boustrophedon script to what ultimately became
7632-421: The less prestigious colloquial registers , attested in inscriptions and some literary works such as those of the comic playwrights Plautus and Terence and the author Petronius . While often called a "dead language", Latin did not undergo language death . By the 6th to 9th centuries, natural language change eventually resulted in Latin as a vernacular language evolving into distinct Romance languages in
7738-455: The model of the structure of DNA. Hodgkin became a reader at Oxford in 1957 and she was given a fully modern laboratory the following year. In 1960, Hodgkin was appointed the Royal Society 's Wolfson Research Professor, a position she held until 1970. This provided her salary, research expenses and research assistance to continue her work at the University of Oxford . She was a fellow of Wolfson College, Oxford , from 1977 to 1983. Hodgkin
7844-772: The monarch's decision on appointments. But, the Royal Household adamantly guarded information about potential names. After 1931, when the Statute of Westminster came into effect and the Dominions of the British Empire became independent countries within the empire, equal in status to the UK, the Order of Merit continued as an honour open to all these realms and, in many, became a part of their newly developing national honours systems. The order's statutes were amended in 1935 to include members of
7950-573: The new League of Nations . In 1921 Hodgkin's father entered her in the Sir John Leman Grammar School in Beccles , England , where she was one of two girls allowed to study chemistry. Only once, when she was 13, did she make an extended visit to her parents, then living in Khartoum , the capital of Sudan, where her father was Principal of Gordon College . When she was 14, her distant cousin,
8056-508: The new University of Warwick. Their daughter, Elizabeth, followed her father's career as a historian. Their younger son, Toby, studied botany and agriculture. Overall, Thomas Hodgkin spent extended periods of time in West Africa, where he was an enthusiastic supporter and chronicler of the emerging postcolonial states. Hodgkin published as "Dorothy Crowfoot" until 1949, when she was persuaded by Hans Clarke's secretary to use her married name on
8162-462: The other varieties, as it was largely separated from the unifying influences in the western part of the Empire. Spoken Latin began to diverge into distinct languages by the 9th century at the latest, when the earliest extant Romance writings begin to appear. They were, throughout the period, confined to everyday speech, as Medieval Latin was used for writing. For many Italians using Latin, though, there
8268-544: The personal gift of its Sovereign—currently Edward VII's great-great-grandson Charles III —and is restricted to a maximum of 24 living recipients from the Commonwealth realms, plus honorary members. While all members are awarded the right to use the post-nominal letters OM and wear the badge of the order, the Order of Merit's precedence among other honours differs between countries. In around 1773, George III considered establishing an order of knighthood to be called
8374-545: The post-nominal letters KMS , and the Order of Artistic Merit, for Knights of Merit in Art, with the post-nominal letters KMA . However, Frederic Leighton , President of the Royal Academy of Arts , advised against the new order, primarily because of its selection process. It was Victoria's son Edward VII who eventually founded the Order of Merit on 26 June 1902 (the date for which his coronation had been originally scheduled ) as
8480-447: The reigning monarch of the realms, currently Charles III , with the assistance of his private secretaries; the order has thus been described as "quite possibly, the most prestigious honour one can receive on planet Earth." Within the limited membership is a designated military division, with its own unique insignia; though it has not been abolished, it is currently unpopulated, Louis Mountbatten, 1st Earl Mountbatten of Burma having been
8586-414: The reverse bears the royal cypher of the reigning monarch in gold. The insignia for the military grouping is distinguished by a pair of crossed swords behind the central disk. The ribbon of the Order of Merit is divided into two stripes of red and blue. The neck ribbon is 50mm in width, while the ribbon bar width is the standard British 32mm size for military or civilian wear. Men wear their badges on
8692-482: The structure actualization could be determined by X-ray crystallography analysis. The large size of the molecule, and the fact that the atoms were largely unaccounted for—aside from cobalt—posed a challenge in structure analysis that had not been previously explored. From these crystals, she deduced the presence of a ring structure because the crystals were pleochroic , a finding which she later confirmed using X-ray crystallography. The B 12 study published by Hodgkin
8798-505: The structure of vitamin B 12 , for which in 1964 she became the third woman to win the Nobel Prize in Chemistry . Hodgkin also elucidated the structure of insulin in 1969 after 35 years of work. Hodgkin used the name "Dorothy Crowfoot" until twelve years after marrying Thomas Lionel Hodgkin , when she began using "Dorothy Crowfoot Hodgkin". Hodgkin is referred to as "Dorothy Hodgkin" by
8904-460: The structure of insulin was put on hold until 1969 when she was finally able to work with her team of young, international scientists to uncover the structure for the first time. Hodgkin's work with insulin was instrumental in paving the way for insulin to be mass-produced and used on a large scale for treatment of both type one and type two diabetes. She went on to cooperate with other laboratories active in insulin research, giving advice, and traveling
9010-410: The structure of insulin. Her first visit to China was in 1959. Over the next quarter century, she travelled there seven more times, the last visit a year before her death. Particularly memorable was the visit in 1971 after the Chinese group themselves independently solved the structure of insulin, later than Hodgkin's team but to a higher resolution. During the subsequent three years, 1972–1975, when she
9116-492: The subject. Though nothing came of the idea at the time, the concept did not wither and, more than 40 years later, on 5 January 1888, Prime Minister Robert Gascoyne-Cecil, 3rd Marquess of Salisbury submitted to the by then long-widowed Queen a draft constitution for an Order of Merit in Science and Art, consisting of one grade split into two branches of knighthood: the Order of Scientific Merit, for Knights of Merit in Science, with
9222-418: The time, that it contains a β-lactam ring. The work was not published until 1949. In 1948, Hodgkin first encountered vitamin B 12 , one of the most structurally complex vitamins known, and created new crystals. Vitamin B 12 had first been discovered at Merck earlier that year. It had a structure at the time that was almost completely unknown, and when Hodgkin discovered it contained cobalt, she realized
9328-465: The work of Elena Ceaușescu , wife of Romania's communist dictator. Hodgkin wrote of the author's "outstanding achievements" and "impressive" career. Following the overthrow of Ceausescu during the Romanian Revolution of 1989 , it was revealed that Elena Ceausescu had neither finished secondary school nor attended university. Her scientific credentials were a hoax , and the publication in question
9434-405: The world giving talks about insulin and its importance for the future of diabetes . Solving the structure of insulin had two important implications for the treatment of diabetes, both making mass production of insulin possible and allowing scientists to alter the structure of insulin to create even better drug options for patients going forward. Hodgkin's soft-spoken, gentle and modest demeanor hid
9540-836: The year after the Intermediate-Range Nuclear Forces Treaty imposed "a global ban on short- and long-range nuclear weapons systems, as well as an intrusive verification regime". She accepted the Lenin Peace Prize from the Soviet government in 1987 in recognition of her work for peace and disarmament. Due to distance, Hodgkin decided not to attend the 1987 Congress of the International Union of Crystallography in Australia. However, despite increasing frailty, she astounded close friends and family by going to Beijing for
9646-549: The youngest person ever inducted into the Order, having been admitted by Queen Elizabeth II in 1968, when he was 47 years old. Robin Eames , Baron Eames represented the order at the coronation of Charles III and Camilla on 6 May 2023. All citizens of the Commonwealth realms are eligible for appointment to the Order of Merit. There may be, however, only 24 living individuals in the order at any given time, not including honorary appointees, and new members are personally selected by
9752-432: Was Bernal who initially took the photographs and gave her additional key insights. Her PhD was awarded in 1937 for research on X-ray crystallography and the chemistry of sterols . In 1933 Hodgkin was awarded a research fellowship by Somerville College, and in 1934, she moved back to Oxford. She started teaching chemistry with her own lab equipment. The college appointed her its first fellow and tutor in chemistry in 1936,
9858-567: Was President of the International Union of Crystallography she was unable to persuade the Chinese authorities, however, to permit the country's scientists to become members of the Union and attend its meetings. Her relations with a supposed scientist in another "People's Democracy" had less happy results. At the age of 73, Hodgkin wrote a foreword to the English edition of Stereospecific Polymerization of Isoprene , published by Robert Maxwell as
9964-519: Was a key scientific adviser to the UK government during the Second World War. He was also an open and vocal member of the Communist Party and a faithful supporter of the Soviet regime until its invasion of Hungary in 1956. He was a chemist who believed in equal opportunity for women. In his laboratory, Hodgkin extended work that he began on biological molecules including sterols. She helped him to make
10070-488: Was asked in later life to name her childhood heroes, she named three women: first and foremost, her mother, Molly ; the medical missionary Mary Slessor ; and Margery Fry , the Principal of Somerville College . In 1928 at age 18 Hodgkin entered Somerville College, Oxford , where she studied chemistry. She graduated in 1932 with a first-class honours degree, the third woman at this institution to achieve this distinction. In
10176-477: Was described by Lawrence Bragg as being as significant "as breaking the sound barrier". Scientists from Merck had previously crystallised B 12 , but had published only refractive indices of the substance. The final structure of B 12 , for which Hodgkin was later awarded the Nobel Prize, was published in 1955 and 1956. Insulin was one of Hodgkin's most extraordinary research projects. It began in 1934 when she
10282-413: Was free to develop on its own, there is no reason to suppose that the speech was uniform either diachronically or geographically. On the contrary, Romanised European populations developed their own dialects of the language, which eventually led to the differentiation of Romance languages . Late Latin is a kind of written Latin used in the 3rd to 6th centuries. This began to diverge from Classical forms at
10388-579: Was in Ghana with her husband when they received the news that she had been awarded the Nobel Prize. She acquired from her mother, Molly, a concern about social inequalities and a determination to do what she could to prevent armed conflict. Dorothy became particularly concerned about the threat of nuclear war. In 1976, she became president of the Pugwash Conference and served longer than any who preceded or succeeded her in this post. She stepped down in 1988,
10494-496: Was much more liberal in its linguistic cohesion: for example, in classical Latin sum and eram are used as auxiliary verbs in the perfect and pluperfect passive, which are compound tenses. Medieval Latin might use fui and fueram instead. Furthermore, the meanings of many words were changed and new words were introduced, often under influence from the vernacular. Identifiable individual styles of classically incorrect Latin prevail. Renaissance Latin, 1300 to 1500, and
10600-441: Was no complete separation between Italian and Latin, even into the beginning of the Renaissance . Petrarch for example saw Latin as a literary version of the spoken language. Medieval Latin is the written Latin in use during that portion of the post-classical period when no corresponding Latin vernacular existed, that is from around 700 to 1500 AD. The spoken language had developed into the various Romance languages; however, in
10706-592: Was offered a small sample of crystalline insulin by Robert Robinson . The hormone captured her imagination because of the intricate and wide-ranging effect it has in the body. However, at this stage X-ray crystallography had not been developed far enough to cope with the complexity of the insulin molecule. She and others spent many years improving the technique. It took 35 years after taking her first photograph of an insulin crystal for X-ray crystallography and computing techniques to be able to tackle larger and more complex molecules like insulin. Hodgkin's dream of unlocking
10812-414: Was one of the first people to travel from Oxford to Cambridge to see the model of the double helix structure of DNA , constructed by Francis Crick and James Watson , which was based on data and technique acquired by Maurice Wilkins and Rosalind Franklin . According to the late Dr Beryl Oughton (married name, Rimmer), they drove to Cambridge in two cars after Hodgkin announced that they were off to see
10918-438: Was particularly noted for discovering three-dimensional biomolecular structures . In 1945, working with C.H. (Harry) Carlisle, she published the first such structure of a steroid , cholesteryl iodide (having worked with cholesteryls since the days of her doctoral studies). In 1945, Hodgkin and her colleagues, including biochemist Barbara Low , solved the structure of penicillin , demonstrating, contrary to scientific opinion at
11024-478: Was shut down in June 2019), and Vatican Radio & Television, all of which broadcast news segments and other material in Latin. A variety of organisations, as well as informal Latin 'circuli' ('circles'), have been founded in more recent times to support the use of spoken Latin. Moreover, a number of university classics departments have begun incorporating communicative pedagogies in their Latin courses. These include
11130-461: Was the first portrait of a woman Fellow to be included in the Society's collection. Member of the Order of Merit The Order of Merit (French: Ordre du Mérite ) is an order of merit for the Commonwealth realms , recognising distinguished service in the armed forces, science, art, literature, or the promotion of culture. Established in 1902 by Edward VII , admission into the order remains
11236-559: Was written for her by a team of scientists to obtain a fraudulent doctorate. Because of Hodgkin's political activities, and her husband's association with the Communist Party, she was banned from entering the US in 1953 and subsequently not allowed to visit the country except by CIA waiver. In 1961 Thomas became an advisor to Kwame Nkrumah , President of Ghana , a country he visited for extended periods before Nkrumah's ouster in 1966. Hodgkin
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