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137-478: Augustus Henry Julian Le Plongeon (4 May 1825 – 13 December 1908) was a British-American antiquarian and photographer who studied the pre-Columbian ruins of America, particularly those of the Maya civilization on the northern Yucatán Peninsula . While his writings contain many notions that were not well received by his contemporaries and were later disproven, Le Plongeon left a lasting legacy in his photographs documenting

274-671: A Level 2 alert (practice enhanced precautions.) A Bayesian analysis of genotypes I and II has shown that genotype I accounts for virtually all the current infections in Brazil , Colombia , Venezuela , and Trinidad and Tobago , while genotype II accounted for all cases in Peru . Genotype I originated in the northern Brazilian region around 1908 (95% highest posterior density interval [HPD]: 1870–1936). Genotype II originated in Peru in 1920 (95% HPD: 1867–1958). The estimated rate of mutation for both genotypes

411-413: A polyprotein . Host proteases cut this polyprotein into three structural (C, prM, E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5); the enumeration corresponds to the arrangement of the protein coding genes in the genome . Minimal YFV 3 ′ UTR region is required for stalling of the host 5 ′ -3 ′ exonuclease XRN1. The UTR contains PKS3 pseudoknot structure, which serves as

548-758: A WHO-approved vaccination center is required. Although 32 of 44 countries where yellow fever occurs endemically do have vaccination programmes, in many of these countries, less than 50% of their population is vaccinated. Control of the yellow fever mosquito A. aegypti is of major importance, especially because the same mosquito can also transmit dengue fever and chikungunya disease. A. aegypti breeds preferentially in water, for example, in installations by inhabitants of areas with precarious drinking water supplies, or in domestic refuse, especially tires, cans, and plastic bottles. These conditions are common in urban areas in developing countries. Two main strategies are employed to reduce A. aegypti populations. One approach

685-570: A billion people live in an area of the world where the disease is common. It is common in tropical areas of the continents of South America and Africa, but not in Asia. Since the 1980s, the number of cases of yellow fever has been increasing. This is believed to be due to fewer people being immune, more people living in cities, people moving frequently, and changing climate increasing the habitat for mosquitoes. The disease originated in Africa and spread to

822-464: A biopsy is only advisable post mortem to confirm the cause of death. In a differential diagnosis , infections with yellow fever must be distinguished from other feverish illnesses such as malaria . Other viral hemorrhagic fevers , such as Ebola virus , Lassa virus , Marburg virus , and Junin virus , must be excluded as the cause. Personal prevention of yellow fever includes vaccination and avoidance of mosquito bites in areas where yellow fever

959-424: A day of improving the fever comes back, abdominal pain occurs, and liver damage begins causing yellow skin . If this occurs, the risk of bleeding and kidney problems is increased. The disease is caused by the yellow fever virus and is spread by the bite of an infected mosquito . It infects humans, other primates , and several types of mosquitoes. In cities, it is spread primarily by Aedes aegypti ,

1096-591: A different social structure. Until the accurate dating of Watson Brake and similar sites, the oldest mound complex was thought to be Poverty Point , also located in the Lower Mississippi Valley . Built about 1500 BCE, it is the centerpiece of a culture extending over 100 sites on both sides of the Mississippi . The Poverty Point site has earthworks in the form of six concentric half-circles, divided by radial aisles, together with some mounds. The entire complex

1233-860: A doctor of medicine. One of his accomplishments as a surveyor included drawing a plan for the layout of the town of Marysville, California in the Central Valley in 1851. Augustus was paid for his services as a surveyor with land deeds. He profited from the sale of these plots and this income would fund the majority of his archaeological expeditions. Le Plongeon traveled to England and saw a demonstration for new photographic processes at The Great Exhibition . He then stayed in England to study photography under William Fox Talbot . Augustus wanted to test these methods in tropical climates so he spent time traveling to St. Thomas, Virgin Islands as well as Mexico, Australia, China, and

1370-461: A few trips back to New York to attempt to sell bas-relief molds to museums, give lectures, and solicit financial backing for their studies. By the 1880s, while most Mayanists accepted that the Maya civilization postdated Ancient Egypt , Le Plongeon stood by his theories. He cited his years of fieldwork and studies of archival sources, and challenged those he considered "armchair" archaeologists to debate

1507-442: A molecular signal to stall the exonuclease and is the only viral requirement for subgenomic flavivirus RNA (sfRNA) production. The sfRNAs are a result of incomplete degradation of the viral genome by the exonuclease and are important for viral pathogenicity. Yellow fever belongs to the group of hemorrhagic fevers . The viruses infect, amongst others, monocytes , macrophages , Schwann cells , and dendritic cells . They attach to

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1644-627: A much later date, probably no more than 2,000 years ago, moving across the ice from Siberia into Alaska. The North American climate was unstable as the ice age receded during the Lithic stage . It finally stabilized about 10,000 years ago; climatic conditions were then very similar to today's. Within this time frame, roughly about the Archaic Period , numerous archaeological cultures have been identified. The unstable climate led to widespread migration, with early Paleo-Indians soon spreading throughout

1781-510: A number of E. G. Squier 's expeditions and took photographs out in the field. Le Plongeon was influenced by the work of Charles Étienne Brasseur de Bourbourg , John Lloyd Stephens , and Frederick Catherwood . These works, in combination with his own explorations in Peru, led Le Plongeon to believe that civilization had its origins in the New World. While in Peru Augustus became interested in

1918-595: A number of illustrated lectures at the California Academy of Sciences on Peruvian archaeology and the causes of earthquakes. His travels then continued on to New York City, and by 1871 he was at the British Museum in London studying Mesoamerican manuscripts. While in London he met Alice Dixon , the woman with whom he would collaborate for the rest of his life. Alice was born in London in 1851. Her father, Henry Dixon,

2055-730: A population of over 20,000. Other chiefdoms were constructed throughout the Southeast, and its trade networks reached to the Great Lakes and the Gulf of Mexico. At its peak, between the 12th and 13th centuries, Cahokia was the most populous city in North America. (Larger cities did exist in Mesoamerica and the Andes.) Monks Mound , the major ceremonial center of Cahokia, remains the largest earthen construction of

2192-493: A rearrangement of the 90 homo dimers to 60 homo trimers . After entering the host cell, the viral genome is replicated in the rough endoplasmic reticulum (ER) and in the so-called vesicle packets. At first, an immature form of the virus particle is produced inside the ER, whose M-protein is not yet cleaved to its mature form, so is denoted as precursor M (prM) and forms a complex with protein E. The immature particles are processed in

2329-549: A reduced volume of vaccine dose, which has been reconstituted as per manufacturer recommendations. The first practical use of fractional dose yellow fever vaccination was in response to a large yellow fever outbreak in the Democratic Republic of the Congo in mid-2016. Available evidence shows that fractional dose yellow fever vaccination induces a level of immune response similar to that of the standard full dose. In March 2017,

2466-570: A single unified empire. The Mixtecs would eventually be conquered by the Aztecs until the Spanish conquest. The Mixtecs saw the Spanish conquest as an opportunity for liberation and established agreements with the conquistadors that allowed them to preserve their cultural traditions, though relatively few sections resisted Spanish rule. The Totonac civilization was concentrated in the present-day states of Veracruz and Puebla . The Totonacs were responsible for

2603-530: A structure known as the Platform of the Eagles and Jaguars and unearthed a large statue or altar figurine. They coined the name "Chaacmol" (later " Chac Mool " or chacmool ) for it. Although their derivation of the name is known now to have had no association with figures of this type, the name has remained in general use among later archaeologists. This statue would later be used as a demonstration of Toltec influences at

2740-494: A type of mosquito found throughout the tropics and subtropics . The virus is an RNA virus of the genus Flavivirus . The disease may be difficult to tell apart from other illnesses, especially in the early stages. To confirm a suspected case, blood-sample testing with a polymerase chain reaction is required. A safe and effective vaccine against yellow fever exists, and some countries require vaccinations for travelers. Other efforts to prevent infection include reducing

2877-456: A variety of tools, including distinctive projectile points and knives, as well as less distinctive butchering and hide-scraping implements. The vastness of the North American continent, and the variety of its climates, ecology , vegetation , fauna , and landforms, led ancient peoples to coalesce into many distinct linguistic and cultural groups. This is reflected in the oral histories of

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3014-614: Is Y-chromosome haplogroup Q1a3a . Researchers have found genetic evidence that the Q1a3a haplogroup has been in South America since at least 18,000 BCE. Y-chromosome DNA , like mtDNA , differs from other nuclear chromosomes in that the majority of the Y-chromosome is unique and does not recombine during meiosis . This has the effect that the historical pattern of mutations can easily be studied. The pattern indicates Indigenous peoples of

3151-421: Is common in tropical and subtropical areas of South America and Africa. Worldwide, about 600 million people live in endemic areas. The WHO estimates 200,000 cases of yellow fever worldwide each year. About 15% of people infected with yellow fever progress to a severe form of the illness, and up to half of those will die, as there is no cure for yellow fever. An estimated 90% of yellow fever infections occur on

3288-431: Is caused by yellow fever virus (YFV), an enveloped RNA virus 40–50 nm in width, the type species and namesake of the family Flaviviridae . It was the first illness shown to be transmissible by filtered human serum and transmitted by mosquitoes, by American doctor Walter Reed around 1900. The positive- sense , single-stranded RNA is around 10,862 nucleotides long and has a single open reading frame encoding

3425-625: Is endemic. Institutional measures for prevention of yellow fever include vaccination programmes and measures to control mosquitoes. Programmes for distribution of mosquito nets for use in homes produce reductions in cases of both malaria and yellow fever. Use of EPA-registered insect repellent is recommended when outdoors. Exposure for even a short time is enough for a potential mosquito bite. Long-sleeved clothing, long pants, and socks are useful for prevention. The application of larvicides to water-storage containers can help eliminate potential mosquito breeding sites. EPA-registered insecticide spray decreases

3562-643: Is fatal in 60% of cases. It is probably due to the genetic morphology of the immune system. Another possible side effect is an infection of the nervous system, which occurs in one in 200,000 to 300,000 cases, causing yellow fever vaccine-associated neurotropic disease, which can lead to meningoencephalitis and is fatal in less than 5% of cases. The Yellow Fever Initiative, launched by the WHO in 2006, vaccinated more than 105 million people in 14 countries in West Africa. No outbreaks were reported during 2015. The campaign

3699-504: Is known as acquired immunity . The virus, as well as the vector A. aegypti, were probably transferred to North and South America with the trafficking of slaves from Africa, part of the Columbian exchange following European exploration and colonization. However, some researchers have argued that yellow fever might have existed in the Americas during the pre-Columbian period as mosquitoes of

3836-411: Is nearly a mile across. Mound building was continued by succeeding cultures, who built numerous sites in the middle Mississippi and Ohio River valleys as well, adding effigy mounds , conical and ridge mounds, and other shapes. The Woodland period of North American pre-Columbian cultures lasted from roughly 1000 BCE to 1000 CE. The term was coined in the 1930s and refers to prehistoric sites between

3973-470: Is not recommended by the WHO. Insecticide-treated mosquito nets are effective, just as they are against the Anopheles mosquito that carries malaria. As with other Flavivirus infections, no cure is known for yellow fever. Hospitalization is advisable and intensive care may be necessary because of rapid deterioration in some cases. Certain acute treatment methods lack efficacy: passive immunization after

4110-410: Is recommended as a chemical larvicide, mainly because it is safe for humans and effective in small doses. The second strategy is to reduce populations of the adult yellow fever mosquito. Lethal ovitraps can reduce Aedes populations, using lesser amounts of pesticide because it targets the pest directly. Curtains and lids of water tanks can be sprayed with insecticides, but application inside houses

4247-427: Is taken up by a female mosquito when it ingests the blood of an infected human or another primate. Viruses reach the stomach of the mosquito, and if the virus concentration is high enough, the virions can infect epithelial cells and replicate there. From there, they reach the haemocoel (the blood system of mosquitoes) and from there the salivary glands . When the mosquito next sucks blood, it injects its saliva into

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4384-578: Is the Olmec. This civilization established the cultural blueprint by which all succeeding indigenous civilizations would follow in Mexico. Pre-Olmec civilization began with the production of pottery in abundance, around 2300 BCE in the Grijalva River delta. Between 1600 and 1500 BCE, the Olmec civilization had begun, with the consolidation of power at their capital, a site today known as San Lorenzo Tenochtitlán near

4521-543: Is the absence of a slave trade to Asia on the scale of that to the Americas. The trans-Atlantic slave trade probably introduced yellow fever into the Western Hemisphere from Africa. The evolutionary origins of yellow fever most likely lie in Africa, with transmission of the disease from nonhuman primates to humans. The virus is thought to have originated in East or Central Africa and spread from there to West Africa. As it

4658-507: Is to kill the developing larvae. Measures are taken to reduce the water accumulations in which the larvae develop. Larvicides are used, along with larvae-eating fish and copepods , which reduce the number of larvae. For many years, copepods of the genus Mesocyclops have been used in Vietnam for preventing dengue fever. This eradicated the mosquito vector in several areas. Similar efforts may prove effective against yellow fever. Pyriproxyfen

4795-658: The Archaic period and the Mississippian cultures . The Adena culture and the ensuing Hopewell tradition during this period built monumental earthwork architecture and established continent-spanning trade and exchange networks. This period is considered a developmental stage without any massive changes in a short period but instead has a continuous development in stone and bone tools, leatherworking, textile manufacture, tool production, cultivation, and shelter construction. Some Woodland people continued to use spears and atlatls until

4932-672: The Cliff Palace of Mesa Verde National Park in Colorado and the Great Houses in Chaco Canyon , New Mexico . The Puebloans also constructed a road system that stretched from Chaco Canyon to Kutz Canyon in the San Juan Basin . The Ancestral Puebloans are also known as "Anasazi", though the term is controversial, as the present-day Pueblo peoples consider the term to be derogatory, due to

5069-545: The Golgi apparatus by the host protein furin , which cleaves prM to M. This releases E from the complex, which can now take its place in the mature, infectious virion . Yellow fever virus is mainly transmitted through the bite of the yellow fever mosquito Aedes aegypti , but other mostly Aedes mosquitoes such as the tiger mosquito ( Aedes albopictus ) can also serve as a vector for this virus. Like other arboviruses , which are transmitted by mosquitoes, yellow fever virus

5206-624: The Maya script . Other accounts also suggest that the Huastecs migrated as a result of the Classic Maya collapse around the year 900 CE. The Zapotecs were a civilization that thrived in the Oaxaca Valley from the late 6th century BCE until their downfall at the hands of the Spanish conquistadors. The city of Monte Albán was an important religious center for the Zapotecs and served as the capital of

5343-684: The Napoleonic Wars , the West Indies were known as a particularly dangerous posting for soldiers due to yellow fever being endemic in the area. The mortality rate in British garrisons in Jamaica was seven times that of garrisons in Canada, mostly because of yellow fever and other tropical diseases. Both English and French forces posted there were seriously affected by the "yellow jack." Wanting to regain control of

5480-651: The Olmec , Teotihuacan , Mayas , Zapotecs , Mixtecs , Huastecs , Purepecha , Toltecs , and Mexica / Aztecs . The Mexica civilization is also known as the Aztec Triple Alliance since they were three smaller kingdoms loosely united together. These Indigenous civilizations are credited with many inventions: building pyramid temples, mathematics , astronomy , medicine, writing, highly accurate calendars , fine arts , intensive agriculture, engineering , an abacus calculator, and complex theology . They also invented

5617-477: The Spanish conquest of El Salvador , Cuzcatlan was forced to surrender to conquistador Pedro de Alvarado in 1528. Yellow fever Yellow fever is a viral disease of typically short duration . In most cases, symptoms include fever , chills , loss of appetite , nausea , muscle pains—particularly in the back—and headaches . Symptoms typically improve within five days. In about 15% of people, within

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5754-458: The Tlingit , Haida , Chumash , Mandan , Hidatsa , and others, and some established large settlements, even cities, such as Cahokia , in what is now Illinois . Mesoamerica is the region extending from central Mexico south to the northwestern border of Costa Rica that gave rise to a group of stratified, culturally related agrarian civilizations spanning an approximately 3,000-year period before

5891-500: The founding population . The microsatellite diversity and distributions of the Y lineage specific to South America indicate that certain Amerindian populations have been isolated since the initial colonization of the region. The Na-Dené , Inuit , and Indigenous Alaskan populations exhibit haplogroup Q-M242 (Y-DNA) mutations, however, and are distinct from other Indigenous peoples with various mtDNA mutations. This suggests that

6028-653: The African continent. In 2016, a large outbreak originated in Angola and spread to neighboring countries before being contained by a massive vaccination campaign. In March and April 2016, 11 imported cases of the Angola genotype in unvaccinated Chinese nationals were reported in China, the first appearance of the disease in Asia in recorded history. Phylogenetic analysis has identified seven genotypes of yellow fever viruses, and they are assumed to be differently adapted to humans and to

6165-507: The Americas experienced two very distinctive genetic episodes: first with the initial peopling of the Americas and second with European colonization of the Americas . The former is the determinant factor for the number of gene lineages and founding haplotypes present in today's Indigenous populations . Human settlement of the Americas occurred in stages from the Bering Sea coastline , with an initial 20,000-year layover on Beringia for

6302-521: The Americas starting in the 17th century with the European trafficking of enslaved Africans from sub-Saharan Africa. Since the 17th century, several major outbreaks of the disease have occurred in the Americas, Africa, and Europe. In the 18th and 19th centuries, yellow fever was considered one of the most dangerous infectious diseases ; numerous epidemics swept through major cities of the US and in other parts of

6439-598: The Americas, diversifying into many hundreds of culturally distinct tribes. The Paleo-Indians were hunter-gatherers , likely characterized by small, mobile bands consisting of approximately 20 to 50 members of an extended family. These groups moved from place to place as preferred resources were depleted and new supplies were sought. During much of the Paleo-Indian period, bands are thought to have subsisted primarily through hunting now-extinct giant land animals such as mastodon and ancient bison . Paleo-Indian groups carried

6576-523: The Democratic Republic of Congo (2016), Uganda (2016), and more recently in Nigeria and Brazil in 2017 have further increased demand, while straining global vaccine supply. Therefore, to vaccinate susceptible populations in preventive mass immunization campaigns during outbreaks, fractional dosing of the vaccine is being considered as a dose-sparing strategy to maximize limited vaccine supplies. Fractional dose yellow fever vaccination refers to administration of

6713-790: The East African genotype, which had remained undetected in the previous 40 years. In South America, two genotypes have been identified (South American genotypes I and II). Based on phylogenetic analysis these two genotypes appear to have originated in West Africa and were first introduced into Brazil. The date of introduction of the predecessor African genotype which gave rise to the South American genotypes appears to be 1822 (95% confidence interval 1701 to 1911). The historical record shows an outbreak of yellow fever occurred in Recife, Brazil, between 1685 and 1690. The disease seems to have disappeared, with

6850-472: The Europeans arrived, Indigenous peoples of North America had a wide range of lifeways from sedentary, agrarian societies to semi-nomadic hunter-gatherer societies. Many formed new tribes or confederations in response to European colonization. These are often classified by cultural regions , loosely based on geography. These can include the following: Numerous pre-Columbian societies were sedentary, such as

6987-648: The Hohokam, they constructed kivas and great houses as well as ballcourts . Several of the Sinagua ruins include Montezuma Castle , Wupatki , and Tuzigoot . The Salado resided in the Tonto Basin in southeastern Arizona from 1150 CE to the 15th century. Archaeological evidence suggests that they traded with far-away cultures, as evidenced by the presence of seashells from the Gulf of California and macaw feathers from Mexico. Most of

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7124-635: The Le Plongeons made a short excursion to Uxmal . The Le Plongeons were in Yucatán during the Caste War , a conflict between the Maya, called the Chan Santa Cruz, and the army of Yucatán. When they traveled to Chichen Itza in 1875, they were accompanied by a military escort. When they arrived at the site, local Maya men were hired to clear the vegetation and help with excavations. The Le Plongeons were some of

7261-660: The Maya city of Chichen Itza . The Toltecs established vast trading relations with other Mesoamerican civilizations in Central America and the Puebloans in present-day New Mexico . During the Post-Classic era, the Toltecs suffered a subsequent collapse in the early 12th century, due to famine and civil war. The Toltec civilization was so influential to the point where many groups such as the Aztecs claimed to be descended from. With

7398-450: The Maya civilization cannot be overstated: it transformed political power, artistic depictions, and the nature of economics. Within the city of Teotihuacan was a diverse and cosmopolitan population. Most of the regional ethnicities of Mexico were represented in the city, such as Zapotecs from the Oaxaca region. They lived in apartment communities where they worked their trades and contributed to

7535-514: The Maya sites in Yucatán being the cradle of civilization , with civilization then traveling east first to Atlantis and later to Ancient Egypt . The Le Plongeons named kings and queens of these dynasties and said that various artworks were portraits of such ancient royalty (such as the famous Chacmool , which the couple excavated at Chichén Itzá). The Le Plongeons reconstructed a detailed but fanciful story of Queen Moo and Prince Coh (also known as "Chac Mool") in which Prince Coh's death resulted in

7672-802: The Mississippian groups had vanished, and vast swaths of their territory were virtually uninhabited. The Ancestral Puebloans thrived in what is now the Four Corners region in the United States. It is commonly suggested that the culture of the Ancestral Puebloans emerged during the Early Basketmaker II Era during the 12th century BCE. The Ancestral Puebloans were a complex Oasisamerican society that constructed kivas , multi-story houses, and apartment blocks made from stone and adobe, such as

7809-483: The Olmec resulted in a power vacuum in Mexico. Emerging from that vacuum was Teotihuacan, first settled in 300 BCE. By 150 CE, Teotihuacan had risen to become the first true metropolis of what is now called North America. Teotihuacan established a new economic and political order never before seen in Mexico. Its influence stretched across Mexico into Central America, founding new dynasties in the Maya cities of Tikal , Copan , and Kaminaljuyú . Teotihuacan's influence over

7946-732: The Olmecs, Teotihuacan, the Toltecs, the Mexica, and the Mayas. These civilizations (except for the politically fragmented Maya) extended their reach across Mesoamerica—and beyond—like no others. They consolidated power and distributed influence in matters of trade, art, politics, technology, and theology. Other regional power players made economic and political alliances with these civilizations over 4,000 years. Many made war with them, but almost all peoples found themselves within one of their spheres of influence. Regional communications in ancient Mesoamerica have been

8083-610: The Pacific Islands. He returned to San Francisco to open a daguerreotype portrait studio on Clay Street. In 1862, he traveled to Lima, Peru and opened another photography studio and an "electro-hydropathic" medical clinic based on an early form of alternative medicine. Le Plongeon pioneered the use of photography as a tool for his studies. He began using the wet collodion glass-plate negative process he used for studio portraits to record his explorations. He traveled extensively all over Peru for eight years visiting and photographing ancient ruins, including Tiahuanaco . Augustus also joined

8220-459: The Spanish colonists. The Wichita people were a loose confederation that consisted of sedentary agriculturalists and hunter-gatherers who resided in the eastern Great Plains . They lived in permanent settlements and even established a city called Etzanoa , which had a population of 20,000 people. The city was eventually abandoned around the 18th century after it was encountered by Spanish conquistadors Jusepe Gutierrez and Juan de Oñate . When

8357-445: The Tlaxcalans for preserving their culture and for their assistance in defeating the Aztecs. The Tlaxcalans would once again assist to the Spaniards during the Mixtón War and the conquest of Guatemala . Cuzcatlan was a Pipil confederacy of kingdoms and city-states located in present-day El Salvador . According to legend, Cuzcatlan was established by Toltec migrants during the Classic Maya collapse in approximately 1200 CE. During

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8494-465: The WHO launched a vaccination campaign in Brazil with 3.5 million doses from an emergency stockpile. In March 2017 the WHO recommended vaccination for travellers to certain parts of Brazil. In March 2018, Brazil shifted its policy and announced it planned to vaccinate all 77.5 million currently unvaccinated citizens by April 2019. Some countries in Asia are considered to be potentially in danger of yellow fever epidemics, as both mosquitoes with

8631-409: The WHO on 17 May 2013 advised that subsequent booster vaccinations are unnecessary, an older (than 10 years) certificate may not be acceptable at all border posts in all affected countries. A list of the countries that require yellow fever vaccination is published by the WHO. If the vaccination cannot be given for some reason, dispensation may be possible. In this case, an exemption certificate issued by

8768-504: The age of eighty-three; Alice followed in 1910 at the age of fifty-nine. A collection of the works of the Le Plongeons currently resides at the Getty Research Institute in Los Angeles . The archive contains original records covering their travels from the 1860s through the early 1900s, including diaries, unpublished scholarly manuscripts and notes, correspondence, and extensive photographic documentation of ancient architecture and sculpture, city views, and ethnographic studies. Le Plongeon

8905-442: The ancient ruins. He was one of the earliest proponents of Mayanism . Le Plongeon was born on the island of Jersey on 4 May 1825. At 19, he sailed to South America and shipwrecked off the coast of Chile . While there he settled in Valparaiso and taught mathematics, drawing, and languages at a local college. In 1849 he sailed to San Francisco during the California gold rush to work as a surveyor , and also apprenticed to become

9042-443: The calendar, were bequest from the former inhabitants of Tula, the Toltecs. The Mexica-Aztecs were the rulers of much of central Mexico by about 1400 (while Yaquis , Coras, and Apaches commanded sizable regions of northern desert), having subjugated most of the other regional states by the 1470s. At their peak, the Valley of Mexico where the Aztec Empire presided, saw a population growth that included nearly one million people during

9179-407: The capability to transmit yellow fever as well as susceptible monkeys are present. The disease does not yet occur in Asia. To prevent introduction of the virus, some countries demand previous vaccination of foreign visitors who have passed through yellow fever areas. Vaccination has to be proved by a vaccination certificate, which is valid 10 days after the vaccination and lasts for 10 years. Although

9316-510: The causes of earthquakes. He was able to observe the 1868 Arica earthquake and he studied the resulting damage and interviewed people about what they experienced. During this time Le Plongeon began to speak out against abuses by Jesuit priests and the Catholic Church in Peru. He published two anti-Jesuit books, La religion de Jesus comparada con las ensenanzas de la Iglesia (1867), and Los Jesuitas y el Peru (1869). In 1870, he left Peru and traveled back once again to San Francisco where he gave

9453-399: The cell surfaces via specific receptors and are taken up by an endosomal vesicle . Inside the endosome , the decreased pH induces the fusion of the endosomal membrane with the virus envelope . The capsid enters the cytosol , decays, and releases the genome. Receptor binding, as well as membrane fusion, are catalyzed by the protein E, which changes its conformation at low pH, causing

9590-457: The city's economic and cultural prowess. Teotihuacan's economic pull impacted areas in northern Mexico as well. It was a city whose monumental architecture reflected a monumental new era in Mexican civilization, declining in political power about 650 CE—but lasting in cultural influence for the better part of a millennium, to around 950 CE. Contemporary to Teotihuacan's greatness was that of the Maya civilization. The period between 250 CE and 650 CE

9727-406: The civilizations in its area, the Tarascan Empire was the most prominent in metallurgy, harnessing copper, silver, and gold to create items such as tools, decorations, and even weapons and armor. Bronze was also used. The great victories over the Aztecs by the Tarascans cannot be understated. Nearly every war they fought in resulted in a Tarascan victory. Because the Tarascan Empire had little links to

9864-712: The cliff dwellings constructed by the Salado are primarily located in Tonto National Monument . The Iroquois League of Nations or "People of the Long House" was a politically advanced, democratic society, which is thought by some historians to have influenced the United States Constitution , with the Senate passing a resolution to this effect in 1988. Other historians have contested this interpretation and believe

10001-404: The coast in southeast Veracruz . The Olmec influence extended across Mexico, into Central America , and along the Gulf of Mexico . They transformed many peoples' thinking toward a new way of government, pyramid temples, writing, astronomy, art, mathematics, economics, and religion. Their achievements paved the way for the Maya civilization and the civilizations in central Mexico. The decline of

10138-489: The colonization of the Americas dates from between 40,000 and 13,000 years ago. The chronology of migration models is currently divided into two general approaches. The first is the short chronology theory with the first movement beyond Alaska into the Americas occurring no earlier than 14,000–17,000 years ago, followed by successive waves of immigrants. The second belief is the long chronology theory , which proposes that

10275-541: The de Soto expedition wandered the American Southeast for four years, becoming more bedraggled, losing more men and equipment, and eventually arriving in Mexico as a fraction of its original size. The local people fared much worse though, as the fatalities of diseases introduced by the expedition devastated the populations and produced much social disruption. By the time Europeans returned a hundred years later, nearly all of

10412-656: The decline of the Toltec civilization came political fragmentation in the Valley of Mexico . Into this new political game of contenders to the Toltec throne stepped outsiders: the Mexica . They were also a desert people, one of seven groups who formerly called themselves "Azteca", in memory of Aztlán , but they changed their name after years of migrating. Since they were not from the Valley of Mexico , they were initially seen as crude and unrefined in

10549-423: The destruction, a few original documents have survived, and others were transcribed or translated into Spanish, providing modern historians with valuable insights into ancient cultures and knowledge. Before the development of archaeology in the 19th century, historians of the pre-Columbian period mainly interpreted the records of the European conquerors and the accounts of early European travelers and antiquaries. It

10686-472: The detection of IgM or a four-fold increase in IgG titer is considered sufficient indication for yellow fever. As these tests can cross-react with other flaviviruses, such as dengue virus , these indirect methods cannot conclusively prove yellow fever infection. Liver biopsy can verify inflammation and necrosis of hepatocytes and detect viral antigens . Because of the bleeding tendency of yellow fever patients,

10823-562: The disease by the name "yellow fever" occurred in 1744. However, Dr. Mitchell misdiagnosed the disease that he observed and treated, and the disease was probably Weil's disease or hepatitis. McNeill argues that the environmental and ecological disruption caused by the introduction of sugar plantations created the conditions for mosquito and viral reproduction, and subsequent outbreaks of yellow fever. Deforestation reduced populations of insectivorous birds and other creatures that fed on mosquitoes and their eggs. In Colonial times and during

10960-498: The disease can only be confirmed virologically. Since mild cases of yellow fever can also contribute significantly to regional outbreaks, every suspected case of yellow fever (involving symptoms of fever, pain, nausea, and vomiting 6–10 days after leaving the affected area) is treated seriously. If yellow fever is suspected, the virus cannot be confirmed until 6–10 days following the illness. A direct confirmation can be obtained by reverse transcription polymerase chain reaction , where

11097-417: The disease characterized by recurring fever, this time accompanied by jaundice due to liver damage , as well as abdominal pain . Bleeding in the mouth, nose, eyes, and the gastrointestinal tract cause vomit containing blood , hence one of the names in Spanish for yellow fever, vómito negro ("black vomit"). There may also be kidney failure, hiccups, and delirium. Among those who develop jaundice,

11234-638: The earliest migrants into the northern extremes of North America and Greenland derived from later populations. Asian nomadic Paleo-Indians are thought to have entered the Americas via the Bering Land Bridge (Beringia), now the Bering Strait , and possibly along the coast. Genetic evidence found in Indigenous peoples ' maternally inherited mitochondrial DNA (mtDNA) supports the theory of multiple genetic populations migrating from Asia. After crossing

11371-493: The emergence of symptoms is probably without effect; ribavirin and other antiviral drugs , as well as treatment with interferons , are ineffective in yellow fever patients. Symptomatic treatment includes rehydration and pain relief with drugs such as paracetamol (acetaminophen). However, aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) are often avoided because of an increased risk of gastrointestinal bleeding due to their anticoagulant effects. Yellow fever

11508-591: The empire from 700 BCE to 700 CE. The Zapotecs resisted the expansion of the Aztecs until they were subjugated in 1502 under Aztec emperor Ahuitzotl . After the Spanish conquest of the Aztec Empire , the Zapotecs resisted Spanish rule until King Cosijopii I surrendered in 1563. Like the Zapotecs, the Mixtecs thrived in the Oaxaca Valley. The Mixtecs consisted of separate independent kingdoms and city-states, rather than

11645-575: The end of the period when they were replaced by bows and arrows . The Mississippian culture was spread across the Southeast and Midwest of what is today the United States, from the Atlantic coast to the edge of the plains, from the Gulf of Mexico to the Upper Midwest, although most intensively in the area along the Mississippi River and Ohio River . One of the distinguishing features of this culture

11782-612: The erection of monuments in his honor (similar to the commemoration of Prince Albert by Queen Victoria ). While most of Le Plongeon's contemporaries dismissed his theories, individuals such as Ignatius L. Donnelly and Helena Blavatsky drew upon Le Plongeon's research for their own theories. Augustus spent the remainder of his life in Brooklyn, New York , writing about the connections between Maya and Egypt and defending himself against detractors. Augustus le Plongeon died in Brooklyn in 1908 at

11919-457: The establishment of cities, such as El Tajín as important commercial trading centers. The Totonacs would later assist in the Spanish conquest of the Aztec Empire as an opportunity to liberate themselves from Aztec military imperialism. The Toltec civilization was established in the 8th century CE. The Toltec Empire expanded its political borders to as far south as the Yucatán peninsula , including

12056-500: The fatality rate is 20 to 50%, while the overall fatality rate is about 3 to 7.5%. Severe cases may have a mortality rate greater than 50%. Surviving the infection provides lifelong immunity , and normally results in no permanent organ damage. Yellow fever can lead to death for 20% to 50% of those who develop severe disease. Jaundice, fatigue, heart rhythm problems, seizures and internal bleeding may also appear as complications of yellow fever during recovery time. Yellow fever

12193-403: The first Cazonci, Tariacuri, united these communities and built them into one of the most advanced civilizations in Mesoamerica. Their capital at Tzintzuntzan was just one of the many cities—there were ninety more under its control. The Tarascan Empire was among the largest in Central America, so it is no surprise that they routinely came into conflict with the neighboring Aztec Empire . Out of all

12330-458: The first group of people entered the hemisphere at a much earlier date, possibly 50,000–40,000 years ago or earlier. Artifacts have been found in both North and South America which have been dated to 14,000 years ago, and accordingly humans have been proposed to have reached Cape Horn at the southern tip of South America by this time. In that case, the Inuit would have arrived separately and at

12467-708: The first people to photograph and study Chichen Itza. Their photographic work was methodical and systematic, and they took hundreds of 3-D photos . They documented entire Maya buildings, such as the "Governor's Palace" at Uxmal , in overlapping photos by placing the camera on a tall tripod or scaffold to correct for perspective and then processed the plates in the unlit rooms of Maya buildings. In addition to entire facades of buildings, they also photographed small artifacts , and architectural details such as bas-reliefs , Maya hieroglyphic inscriptions, and sculptures . They excavated buildings, drew maps and copied murals, and made molds of bas-reliefs. At Chichen Itza they excavated

12604-400: The former Toltec Empire , they were also quite independent in culture from their neighbors. The Aztecs, Tlaxcaltec , Olmec, Mixtec, Maya, and others were very similar to each other, however. This is because they were all directly preceded by the Toltecs, and they therefore shared almost identical cultures. The Tarascans, however, possessed a unique religion, as well as other things. Tlaxcala

12741-441: The genome of the virus is amplified. Another direct approach is the isolation of the virus and its growth in cell culture using blood plasma ; this can take 1–4 weeks. Serologically, an enzyme-linked immunosorbent assay during the acute phase of the disease using specific IgM against yellow fever or an increase in specific IgG titer (compared to an earlier sample) can confirm yellow fever. Together with clinical symptoms,

12878-555: The genus Haemagogus , which is indigenous to the Americas, have been known to carry the disease. The first definitive outbreak of yellow fever in the New World was in 1647 on the island of Barbados . An outbreak was recorded by Spanish colonists in 1648 in the Yucatán Peninsula , where the indigenous Mayan people called the illness xekik ("blood vomit"). In 1685, Brazil suffered its first epidemic in Recife . The first mention of

13015-592: The impact was minimal or did not exist, pointing to numerous differences between the two systems and the ample precedents for the constitution in European political thought. The Calusa were a complex paramountcy/kingdom that resided in southern Florida . Instead of agriculture, the Calusa economy relied on abundant fishing. According to Spanish sources, the "king's house" at Mound Key was large enough to house 2,000 people. The Calusa ultimately collapsed into extinction at around 1750 after succumbing to diseases introduced by

13152-484: The indigenous peoples, described by a wide range of traditional creation stories which often say that a given people have been living in a certain territory since the creation of the world. Throughout thousands of years, paleo-Indian people domesticated, bred, and cultivated many plant species, including crops that now constitute 50–60% of worldwide agriculture. In general, Arctic, Subarctic, and coastal peoples continued to live as hunters and gatherers, while agriculture

13289-687: The influence that astronomical activities had upon Mesoamerican people before the arrival of Europeans. Many of the later Mesoamerican civilizations carefully built their cities and ceremonial centers according to specific astronomical events. The biggest Mesoamerican cities, such as Teotihuacan , Tenochtitlan , and Cholula , were among the largest in the world. These cities grew as centers of commerce, ideas, ceremonies, and theology, and they radiated influence outwards onto neighboring cultures in central Mexico. While many city-states, kingdoms, and empires competed with one another for power and prestige, Mesoamerica can be said to have had five major civilizations:

13426-432: The issues. However, as evidence mounted against cultural diffusion , Le Plongeon became marginalized and his theories fell further outside the growing mainstream of Maya archaeology. Le Plongeon insisted that the symbols of Freemasonry could be traced to the ancient Maya and that the ancient knowledge had come to ancient Egypt from the ancient Maya by way of Atlantis. He and Alice constructed an imaginative "history," with

13563-441: The jungle and urban cycles. Different mosquitoes of the genus Aedes are involved. In recent years, this has been the most common form of transmission of yellow fever in Africa. Concern exists about yellow fever spreading to southeast Asia, where its vector A. aegypti already occurs. After transmission from a mosquito, the viruses replicate in the lymph nodes and infect dendritic cells in particular. From there, they reach

13700-607: The land bridge, they moved southward along the Pacific coast and through an interior ice-free corridor. Throughout millennia, Paleo-Indians spread throughout the rest of North and South America. Exactly when the first people migrated into the Americas is the subject of much debate. One of the earliest identifiable cultures was the Clovis culture , with sites dating from some 13,000 years ago. However, older sites dating back to 20,000 years ago have been claimed. Some genetic studies estimate

13837-472: The late Aztec period (1350–1519). Their capital, Tenochtitlan , is the site of modern-day Mexico City . At its peak, it was one of the largest cities in the world with population estimates of 200,000–300,000. The market established there was the largest ever seen by the conquistadores on arrival. Initially, the lands that would someday comprise the lands of the powerful Tarascan Empire were inhabited by several independent communities. Around 1300, however,

13974-607: The late twentieth century, archeologists have studied, analyzed, and dated these sites, realizing that the earliest complexes were built by hunter-gatherer societies, whose people occupied the sites on a seasonal basis. Watson Brake , a large complex of eleven platform mounds, was constructed beginning in 3400 BCE and added to over 500 years. This has changed earlier assumptions that complex construction arose only after societies had adopted agriculture, and become sedentary, with stratified hierarchy and usually ceramics. These ancient people had organized to build complex mound projects under

14111-468: The liver and infect hepatocytes (probably indirectly via Kupffer cells ), which leads to eosinophilic degradation of these cells and to the release of cytokines . Apoptotic masses known as Councilman bodies appear in the cytoplasm of hepatocytes. Fatality may occur when cytokine storm , shock , and multiple organ failure follow. Yellow fever is most frequently a clinical diagnosis , based on symptomatology and travel history. Mild cases of

14248-475: The lucrative sugar trade in Saint-Domingue (Hispaniola), and with an eye on regaining France's New World empire, Napoleon sent an army under the command of his brother-in-law General Charles Leclerc to Saint-Domingue to seize control after a slave revolt. The historian J. R. McNeill asserts that yellow fever accounted for about 35,000 to 45,000 casualties of these forces during the fighting. Only one-third of

14385-469: The next outbreak occurring in 1849. It was likely introduced with the trafficking of slaves through the slave trade from Africa. Genotype I has been divided into five subclades, A through E. In late 2016, a large outbreak began in Minas Gerais state of Brazil that was characterized as a sylvatic or jungle epizootic . Real-time phylogenetic investigations at the epicentre of the outbreak revealed that

14522-510: The only true writing system native to the Americas using pictographs and syllabic elements in the form of texts and codices inscribed on stone, pottery, wood, or perishable books made from bark paper. The Huastecs were a Maya ethnic group that migrated northwards to the Gulf Coast of Mexico. The Huastecs are considered to be distinct from the Maya civilization, as they separated from the main Maya branch at around 2000 BCE and did not possess

14659-481: The only way unvaccinated humans can become infected, which explains the low incidence of yellow fever cases on the continent. People who become infected in the jungle can carry the virus to urban areas, where A. aegypti acts as a vector. Because of this sylvatic cycle, yellow fever cannot be eradicated except by completely eradicating the mosquitoes that serve as vectors. In Africa, a third infectious cycle known as "savannah cycle" or intermediate cycle, occurs between

14796-478: The outbreak was caused by the introduction of a virus lineage from the Amazon region into the southeast region around July 2016, spreading rapidly across several neotropical monkey species, including brown howler monkeys, which serve as a sentinel species for yellow fever. No cases had been transmitted between humans by the A. aegypti mosquito, which can sustain urban outbreaks that can spread rapidly. In April 2017,

14933-646: The people abandoned their settlements, likely due to drought. The Mogollon resided in the present-day states of Arizona , New Mexico, and Texas as well as Sonora and Chihuahua . Like most other cultures in Oasisamerica, the Mogollon constructed sophisticated kivas and cliff dwellings. In the village of Paquimé , the Mogollon are revealed to have housed pens for scarlet macaws , which were introduced from Mesoamerica through trade. The Sinagua were hunter-gatherers and agriculturalists who lived in central Arizona. Like

15070-588: The population of the transmitting mosquitoes. In areas where yellow fever is common, early diagnosis of cases and immunization of large parts of the population are important to prevent outbreaks . Once a person is infected, management is symptomatic; no specific measures are effective against the virus. Death occurs in up to half of those who get severe disease. In 2013, yellow fever was estimated to have caused 130,000 severe infections and 78,000 deaths in Africa. Approximately 90 percent of an estimated 200,000 cases of yellow fever per year occur in Africa. Nearly

15207-416: The prehistoric Americas . The culture reached its peak in about 1200–1400 CE, and in most places, it seems to have been in decline before the arrival of Europeans. Many Mississippian peoples were encountered by the expedition of Hernando de Soto in the 1540s, mostly with disastrous results for both sides. Unlike the Spanish expeditions in Mesoamerica, which conquered vast empires with relatively few men,

15344-403: The site, with other examples found at the Toltec capital, Tula . They also documented their excavation of the Platform of Venus with photos as well as plan and cross-section drawings. From 1873 to 1884, the Le Plongeons visited and photographed other Maya sites such as Izamal , Isla Mujeres , Cozumel , Cancún , and Ake , and traveled to Belize (British Honduras). During this time they made

15481-545: The subject of considerable research. There is evidence of trade routes starting as far north as the Mexico Central Plateau , and going down to the Pacific coast. These trade routes and cultural contacts then went on as far as Central America . These networks operated with various interruptions from pre-Olmec times and up to the Late Classical Period (600–900 CE). The earliest known civilization in Mesoamerica

15618-562: The sylvatic outbreak continued moving toward the Brazilian coast, where most people were unvaccinated. By the end of May the outbreak appeared to be declining after more than 3,000 suspected cases, 758 confirmed and 264 deaths confirmed to be yellow fever. The Health Ministry launched a vaccination campaign and was concerned about spread during the Carnival season in February and March. The CDC issued

15755-543: The time of the establishment of the first permanent European colonies, around the late 16th to early 17th centuries, and are known primarily through archaeological research of the Americas and oral histories. Other civilizations, contemporaneous with the colonial period, were documented in European accounts of the time. For instance, the Maya civilization maintained written records, which were often destroyed by Christian Europeans such as Diego de Landa , who viewed them as pagan but sought to preserve native histories. Despite

15892-505: The transmission of yellow fever. Vaccination is recommended for those traveling to affected areas, because non-native people tend to develop more severe illness when infected. Protection begins by the 10th day after vaccine administration in 95% of people, and had been reported to last for at least 10 years. The World Health Organization (WHO) now states that a single dose of vaccine is sufficient to confer lifelong immunity against yellow fever disease. The attenuated live vaccine stem 17D

16029-626: The trip. They married in New York before traveling to Mexico in 1873. In 1873, the Le Plongeons traveled to Yucatán to study ancient Maya sites. Their goal was to explore the possibility of links between the Maya and the civilizations of ancient Egypt and Atlantis. Their first stop was in Mérida and they stayed there while Alice recovered from yellow fever . During her recuperation, the couple made connections with local scholars and both Augustus and Alice learned to speak Yucatec Maya. After Alice had recovered,

16166-516: The urban cycle, both in Africa and South America, a sylvatic cycle (forest or jungle cycle) is present, where Aedes africanus (in Africa) or mosquitoes of the genus Haemagogus and Sabethes (in South America) serve as vectors. In the jungle, the mosquitoes infect mainly nonhuman primates; the disease is mostly asymptomatic in African primates. In South America, the sylvatic cycle is currently

16303-587: The vector A. aegypti . Five genotypes (Angola, Central/East Africa, East Africa, West Africa I, and West Africa II) occur only in Africa. West Africa genotype I is found in Nigeria and the surrounding region. West Africa genotype I appears to be especially infectious, as it is often associated with major outbreaks. The three genotypes found outside of Nigeria and Angola occur in areas where outbreaks are rare. Two outbreaks, in Kenya (1992–1993) and Sudan (2003 and 2005), involved

16440-531: The virus is transmitted from mosquitoes to humans or other primates. In the "urban cycle", only the yellow fever mosquito A. aegypti is involved. It is well adapted to urban areas, and can also transmit other diseases, including Zika fever , dengue fever , and chikungunya . The urban cycle is responsible for the major outbreaks of yellow fever that occur in Africa. Except for an outbreak in Bolivia in 1999, this urban cycle no longer exists in South America. Besides

16577-550: The visits to the Caribbean by Christopher Columbus. Mesoamerican is the adjective generally used to refer to that group of pre-Columbian cultures. This refers to an environmental area occupied by an assortment of ancient cultures that shared religious beliefs, art, architecture, and technology in the Americas for more than three thousand years. Between 2000 and 300 BCE, complex cultures began to form in Mesoamerica. Some matured into advanced pre-Columbian Mesoamerican civilizations such as

16714-496: The ways of the Nahua civilization. Through political maneuvers and ferocious martial skills, they managed to rule Mexico as the head of the 'Triple Alliance' which included two other Aztec cities, Tetxcoco and Tlacopan . Latecomers to Mexico's central plateau , the Mexica thought of themselves, nevertheless, as heirs of the civilizations that had preceded them. For them, arts, sculpture, architecture, engraving, feather-mosaic work, and

16851-420: The wheel, but it was used solely as a toy. In addition, they used native copper , silver , and gold for metalworking. Archaic inscriptions on rocks and rock walls all over northern Mexico (especially in the state of Nuevo León ) demonstrate an early propensity for counting. Their number system was base 20 and included zero . These early count markings were associated with astronomical events and underscore

16988-704: The word tracing its origins to a Navajo word meaning "ancestor enemies". The Hohokam thrived in the Sonoran desert in what is now the U.S. state of Arizona and the Mexican state of Sonora . The Hohokam were responsible for the construction of a series of irrigation canals that led to the successful establishment of Phoenix, Arizona via the Salt River Project . The Hohokam also established complex settlements such as Snaketown , which served as an important commercial trading center. After 1375 CE, Hohokam society collapsed and

17125-423: The world. In 1927, yellow fever virus became the first human virus to be isolated. Yellow fever begins after an incubation period of three to six days. Most cases cause only mild infection with fever, headache, chills, back pain, fatigue, loss of appetite, muscle pain, nausea, and vomiting. In these cases, the infection lasts only three to six days. But in 15% of cases, people enter a second, toxic phase of

17262-461: The wound, and the virus reaches the bloodstream of the bitten person. Transovarial transmissionial and transstadial transmission of yellow fever virus within A. aegypti , that is, the transmission from a female mosquito to its eggs and then larvae, are indicated. This infection of vectors without a previous blood meal seems to play a role in single, sudden breakouts of the disease. Three epidemiologically different infectious cycles occur in which

17399-487: Was a Nahua republic and confederation in central Mexico. The Tlaxcalans fiercely resisted Aztec expansion during the Flower Wars ever since the Aztecs expelled them from Lake Texcoco . The Tlaxcalans would later ally with the Spanish conquistadors under Hernán Cortés as an opportunity to liberate them from the Aztecs and managed to successfully conquer the Aztecs with the help of the conquistadors. The Spaniards would reward

17536-416: Was a time of intense flourishing of Maya civilized accomplishments. While the many Maya city-states never achieved political unity on the order of the central Mexican civilizations, they exerted tremendous intellectual influence upon Mexico and Central America. The Maya built some of the most elaborate cities on the continent and made innovations in mathematics, astronomy, and calendrics. The Maya also developed

17673-437: Was about 5 × 10  substitutions/site/year, similar to that of other RNA viruses. The main vector ( A. aegypti ) also occurs in tropical and subtropical regions of Asia, the Pacific, and Australia, but yellow fever had never occurred there until jet travel introduced 11 cases from the 2016 Angola and DR Congo yellow fever outbreak in Africa. Proposed explanations include: But none is considered satisfactory. Another proposal

17810-573: Was adopted in more temperate and sheltered regions, permitting a dramatic rise in population. After the migration or migrations, it was several thousand years before the first complex societies arose, the earliest emerging about seven to eight thousand years ago. As early as 5500 BCE, people in the Lower Mississippi Valley at Monte Sano and other sites in present-day Louisiana , Mississippi , and Florida were building complex earthwork mounds , probably for religious purposes. Beginning in

17947-411: Was developed in 1937 by Max Theiler . The WHO recommends routine vaccination for people living in affected areas between the 9th and 12th month after birth. Up to one in four people experience fever, aches, and local soreness and redness at the site of injection. In rare cases (less than one in 200,000 to 300,000), the vaccination can cause yellow fever vaccine-associated viscerotropic disease, which

18084-579: Was elected a member of the American Antiquarian Society in 1878. Desmond, Lawrence G. (2009) Yucatan through her eyes: Alice Dixon Le Plongeon, writer and expeditionary photographer. Albuquerque: University of New Mexico Press. Pre-Columbian During the pre-Columbian era, many civilizations developed permanent settlements, cities, agricultural practices, civic and monumental architecture, major earthworks , and complex societal hierarchies. Some of these civilizations had declined by

18221-407: Was endemic in Africa, local populations had developed some immunity to it. When an outbreak of yellow fever would occur in an African community where colonists resided, most Europeans died, while the indigenous Africans usually developed nonlethal symptoms resembling influenza . This phenomenon, in which certain populations develop immunity to yellow fever due to prolonged exposure in their childhood,

18358-562: Was not until the nineteenth century that the work of people such as John Lloyd Stephens , Eduard Seler , and Alfred Maudslay , and institutions such as the Peabody Museum of Archaeology and Ethnology of Harvard University , led to the reconsideration and criticism of the early European sources. Now, the scholarly study of pre-Columbian cultures is most often based on scientific and multidisciplinary methodologies. The haplogroup most commonly associated with Indigenous Amerindian genetics

18495-716: Was recognized in the late nineteenth century for his contribution to the development of panchromatic photography, and for his photos of London architecture taken for the Society for Photographing Relics of Old London . Alice learned the techniques of photography from her father and worked as an assistant in his studio. After meeting Augustus, she became interested in ancient American civilizations and studied John L. Stephen's Incidents of Travel in Yucatan. She agreed to accompany Augustus on an archaeology expedition to study Maya ruins in Mexico. The pair left for New York to finalize preparations for

18632-657: Was supported by the GAVI alliance and governmental organizations in Europe and Africa. According to the WHO, mass vaccination cannot eliminate yellow fever because of the vast number of infected mosquitoes in urban areas of the target countries, but it will significantly reduce the number of people infected. Demand for yellow fever vaccine has continued to increase due to the growing number of countries implementing yellow fever vaccination as part of their routine immunization programmes. Recent upsurges in yellow fever outbreaks in Angola (2015),

18769-538: Was the construction of complexes of large earthen mounds and grand plazas, continuing the mound-building traditions of earlier cultures. They grew maize and other crops intensively, participated in an extensive trade network, and had a complex stratified society. The Mississippians first appeared around 1000 CE, following and developing out of the less agriculturally intensive and less centralized Woodland period. The largest urban site of these people, Cahokia —located near modern East St. Louis, Illinois —may have reached

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